Anti-dandruff shampoo containing selenium disulfide and preparation method of anti-dandruff shampoo

Abstract

The invention provides anti-dandruff shampoo containing selenium disulfide and a preparation method of the anti-dandruff shampoo, and relates to the field of shampoo products. The anti-dandruff shampoo is prepared from the following components in parts by mass: 0.05 to 2.0 parts of selenium disulfide, 10 to 40 parts of a surfactant, 0.05 to 5 parts of a plant composition 1, 0.05 to 5 parts of a plant composition 2, 0.05 to 5 parts of a plant composition 3, 0.05 to 1 part of a preservative and 30 to 80 parts of water, the plant composition 1 comprises a bacillus fermentation product and a myrothamnus flabellifolia leaf or stem extract; the plant composition 2 comprises centella asiatica extract; and the plant composition 3 comprises a carob fruit extract, hydrolyzed lupin protein and a glorybower extract. Selenium disulfide is compounded with the plant composition 1-the plant composition 3, so that the effects of effectively removing dandruff, soothing, moisturizing and relieving itching are achieved, and the technical defect that selenium disulfide is used as an anti-dandruff component is overcome.

Description

Technical Field

[0001] The invention relates to the technical field of shampoo products, and in particular to an anti-dandruff shampoo containing selenium disulfide and a preparation method thereof. Background Art

[0002] Dandruff is a massive desquamation phenomenon caused by excessive proliferation of keratinocytes on the scalp, which affects the lives of many people. Most researchers believe that dandruff is a mild seborrheic dermatitis that occurs on the scalp, manifested by the shedding of clumps of dead skin cells from the scalp. The obvious presence of dandruff may cause social embarrassment to individuals. Long-term dandruff problems may have a negative impact on individuals' psychology. In addition to affecting appearance, dandruff may also be accompanied by uncomfortable symptoms such as itching, tingling or tightness of the scalp. These symptoms may affect the individual's sleep quality and daily quality of life.

[0003] It is currently recognized that the mechanism of seborrheic dermatitis is the uninhibited proliferation of Malassezia yeast. After Malassezia infects the scalp, it may cause abnormal differentiation of keratinocytes, produce proinflammatory cytokines, and damage the skin barrier through a series of mechanisms, thereby leading to increased dandruff. Under the action of lipase, Malassezia degrades triglycerides in fat into free fatty acids, which further stimulate the skin to produce inflammatory reactions and can also cause the appearance of dandruff. Treatment is mainly based on symptomatic treatments such as degreasing, anti-inflammatory, sterilization, and antipruritic. Commonly used topical therapeutic drugs are bifonazole, ciclopirox, ketoconazole, selenium disulfide, zinc pyrithione, tar shampoo, terbinafine and topical glucocorticoids.

[0004] Selenium disulfide has the pharmacological effects of resisting seborrhea, inhibiting the reproduction of Malassezia, and resisting epidermal hyperplasia, and has a good therapeutic effect on dandruff and seborrheic dermatitis of the scalp. However, selenium disulfide lotion has the technical defects of being highly irritating, easily making hair dry and difficult to comb after use. There are existing records in the prior art about preparing shampoo with selenium disulfide.

[0005] Chinese patent CN113648266A discloses a shampoo with hair care function based on selenium disulfide, which is composed of the following raw materials: Chinese herbal extract, Polyporus umbellatus extract, Gleditsia sinensis extract, plant ash, trimethylammonium chloride chitosan, pimaricin, plant essential oil, selenium disulfide, surfactant, rice water, and the Chinese herbal extract is composed of the following raw materials: Vitex rotundifolia, Aconite, Mulberry leaf, Chuanxiong, Polygonum multiflorum, Platycladus orientalis leaf, Gastrodia elata, walnut shell, and the invention uses Chinese herbal extract and plant composition as main ingredients, which is less irritating, has no toxic side effects, is rich in vitamins, proteins and trace elements, and the plant composition can regulate oil secretion and reduce dandruff, and long-term use will not cause damage to hair and scalp. However, the shampoo prepared by the invention focuses on hair care, and the anti-dandruff effect and antibacterial effect are not ideal.

[0006] Chinese patent CN116019739A discloses an anti-dandruff agent, a method for preparing the anti-dandruff agent, and a daily chemical product, wherein the anti-dandruff agent is a water-soluble cyclodextrin; the hydrophobic inner cavity of the water-soluble cyclodextrin is loaded with selenium disulfide; the surface of the water-soluble cyclodextrin is grafted with a quaternary ammonium salt; the content of the anti-dandruff agent in the daily chemical product is 0.5-2%; the daily chemical product is one or more of shampoo, shampoo, shampoo cream, conditioner, water-free shampoo gel, and water-free shampoo spray. However, the product focuses on dandruff removal, and does not consider the technical defects of selenium disulfide lotion, such as high irritation and dry and itchy scalp.

[0007] Based on this, developing a shampoo with both anti-dandruff and soothing effects to solve the defects of selenium disulfide lotion, which is highly irritating and easily causes dry and itchy scalp after use, is the research focus of researchers in this field. Summary of the invention

[0008] In view of the above problems, the present invention provides an anti-dandruff shampoo containing selenium disulfide. The shampoo has both anti-dandruff and soothing and moisturizing effects by compounding selenium disulfide with a plant composition.

[0009] To achieve the above purpose, the technical solution adopted by the present invention is as follows: In one aspect, the present invention provides an anti-dandruff shampoo containing selenium disulfide, which comprises the following components in parts by mass: 0.05-2.0 parts of selenium disulfide, 10-40 parts of surfactant, 0.05-5 parts of plant composition 1, 0.05-5 parts of plant composition 2, 0.05-5 parts of plant composition 3, 0.05-1 part of preservative and 30-80 parts of water; The plant composition 1 comprises a Bacillus fermentation product and a Milo leaf or stem extract; The plant composition 2 comprises a Centella asiatica extract; The plant composition 3 comprises Ceratonia suffruticosa fruit extract, hydrolyzed lupin protein and Psoralea corylifolia flower extract.

[0010] Preferably, the following components are included by weight: 0.5 parts to 1.5 parts of selenium disulfide, 15 parts to 30 parts of surfactant, 1 part to 4 parts of plant composition 1, 1 part to 4 parts of plant composition 2, 1 part to 4 parts of plant composition 3, 0.1 parts to 0.8 parts of preservative and 50 parts to 70 parts of water.

[0011] Further preferably, the following components are included by weight: 0.8-1 parts of selenium disulfide, 20-30 parts of surfactant, 1-3 parts of plant composition 1, 1-3 parts of plant composition 2, 1-3 parts of plant composition 3, 0.1-0.5 parts of preservative and 60-70 parts of water.

[0012] Preferably, the water is selected from at least one of deionized water, ultrapure water and pure water; further preferably, the water is deionized water.

[0013] Preferably, the plant composition 1 is a mixture of a Bacillus fermentation product, an extract of Milostachys chinensis leaves or stems, p-hydroxyacetophenone and 1,2-pentanediol; Preferably, the mass ratio of the Bacillus fermentation product, the Milo leaf or stem extract, p-hydroxyacetophenone and 1,2-pentanediol is 0.8-1.2:0.1-0.5:0.1-0.5:0.05-0.2.

[0014] Further preferably, the mass ratio of the Bacillus fermentation product, the Milo leaf or stem extract, p-hydroxyacetophenone and 1,2-pentanediol is 1:0.3:0.3:0.1.

[0015] Preferably, the plant composition 2 is a mixture of Centella asiatica extract and propylene glycol; Preferably, the mass ratio of the Centella asiatica extract to propylene glycol is 1:5-10; Further preferably, the mass ratio of the Centella asiatica extract to propylene glycol is 1:9; Preferably, the plant composition 3 is a mixture of Ceratonia suffruticosa fruit extract, hydrolyzed lupine protein, Scutellaria baicalensis flower extract, ethylhexylglycerin, 1,2-hexanediol, glycerin and water; Preferably, the mass ratio of the carob fruit extract, hydrolyzed lupine protein, euphorbia cerifera extract, ethylhexylglycerin, 1,2-hexanediol, glycerol and water is 0.8-1.2:0.5-1.2:0.05-0.2:0.5-1.5:20-30:15-25.

[0016] Further preferably, the mass ratio of the carob fruit extract, hydrolyzed lupine protein, safflower flower extract, ethylhexylglycerin, 1,2-hexanediol, glycerol and water is 1:0.9:1:0.1:1:25:21.

[0017] Preferably, the mass ratio of the plant composition 1, the plant composition 2 and the plant composition 3 is 0.1-4:0.1-4:0.1-4; further preferably, the mass ratio of the plant composition 1, the plant composition 2 and the plant composition 3 is 1-3:1-3:1-3.

[0018] Preferably, the surfactant is selected from at least two of sodium laureth sulfate, ammonium lauryl sulfate, cocamidopropyl betaine, sodium methyl cocoyl taurate, disodium cocoyl glutamate and sodium lauroyl sarcosinate.

[0019] Further preferably, the surfactant is sodium laureth sulfate, ammonium lauryl sulfate and cocamidopropyl betaine.

[0020] Preferably, the mass ratio of the surfactants sodium laureth sulfate, ammonium lauryl sulfate and cocamidopropyl betaine is 10-15:1-6:2-5.

[0021] Further preferably, the mass ratio of the surfactants sodium laureth sulfate, ammonium lauryl sulfate, and cocamidopropyl betaine is 10-12:1-3:3-5.

[0022] Preferably, the preservative is selected from at least one of phenoxyethanol, potassium sorbate, kasone, iodopropynyl butylcarbamate, ethylhexylglycerin, glyceryl laurate, glyceryl caprylate, sodium benzoate, benzyl alcohol, and sodium salicylate.

[0023] In addition, the selenium disulfide shampoo of the present invention may further include at least one of the following ingredients: (1) Hair conditioning agents: for example, at least one of guar hydroxypropyltrimonium chloride, polyquaternium-7, polyquaternium-10, polyquaternium-67, polyquaternium-47, polyquaternium-22, stearamidopropyl dimethylamine, glycerin, salicylic acid, menthol and emulsified silicone oil; (2) Suspending agent: for example, at least one of acrylic acid (ester) copolymer, acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, bentonite, microcrystalline cellulose, distearyl phthalamide, hydroxypropyl starch phosphate, and hydrogenated castor oil; (3) pH adjuster: for example, at least one of citric acid, lactic acid, sodium hydroxide, sodium citrate and arginine; (4) Chelating agent: for example, at least one of disodium EDTA, sodium dihydrogen phosphate, HEPES buffer and disodium hydrogen phosphate; (5) Flavors and pigments.

[0024] Preferably, the anti-dandruff shampoo containing selenium disulfide comprises the following components in parts by mass: 0.05-2.0 parts of selenium disulfide, 10-40 parts of surfactants, 0.05-5 parts of plant composition 1, 0.05-5 parts of plant composition 2, 0.05-5 parts of plant composition 3, 0.1-0.5 parts of hair conditioners, 1-4 parts of suspending agents, 0.1-0.3 parts of pH regulators, 0.05-0.15 parts of chelating agents, 0.1-1 parts of fragrances, 0.05-1 parts of preservatives, and 30-80 parts of water; On the other hand, the present invention provides a method for preparing the above-mentioned anti-dandruff shampoo containing selenium disulfide, comprising the following steps: Step 1: Mix water and surfactant, raise the temperature to 83-85°C, and keep the temperature for 30 minutes to obtain mixture 1.

[0025] Step 2: Stir the mixture 1 and cool it to below 40° C., add selenium disulfide, plant composition 1, plant composition 2, plant composition 3 and a preservative, and stir evenly to obtain an anti-dandruff shampoo containing selenium disulfide.

[0026] Preferably, the preparation method comprises the following steps: S1: Mix water, chelating agent, hair conditioning agent and suspending agent, raise the temperature to 80-85° C., and keep the temperature for 20-40 minutes to obtain mixture 1; S2: Cooling the mixture 1 to below 40° C., adding selenium disulfide and mixing, to obtain a mixture 2; S3: Mix the mixture 2 with the plant composition 1, the plant composition 2, the plant composition 3, the pH regulator, the essence and the pigment, and stir evenly to obtain an anti-dandruff shampoo containing selenium disulfide.

[0027] Compared with the prior art, the present invention has the following beneficial effects: The present invention compounds selenium disulfide with plant composition 1, plant composition 2 and plant composition 3, and achieves soothing and moisturizing effects on the basis of effective dandruff removal through specific components and specific ratios, thereby solving the technical defects of selenium disulfide being used as an anti-dandruff ingredient. DETAILED DESCRIPTION

[0028] In order to make the technical means, creative features, purpose and effect of the present invention easy to understand, the present invention is further explained below in conjunction with specific embodiments, but the following embodiments are only preferred embodiments of the present invention, not all. Based on the embodiments in the implementation mode, other embodiments obtained by those skilled in the art without making creative work all belong to the protection scope of the present invention. It is worth noting that the raw materials used in the present invention are all common commercial products, and their sources are not specifically limited. The technology and scientific terms used in the embodiments have the meanings commonly understood by those of ordinary skill in the art to which the present invention belongs.

[0029] Purchase information of raw materials used in this invention: Sodium laureth sulfate was purchased from BASF (China) Co., Ltd., model number Texapon® N 70; Ammonium lauryl sulfate was purchased from BASF (China) Co., Ltd., model number Texapon® ALS 1470; Cocamidopropyl betaine was purchased from Guangzhou Xingye Technology Co., Ltd., model Ucefactant BE-35F; Plant composition 1 was purchased from Guangdong Xuanjia Medical Health Technology Co., Ltd., model SHINE+ resurrection grass fermentation liquid; Plant composition 2 was purchased from Beijing Sanyou Huizhi Biotechnology Co., Ltd., model SH-525; The plant composition 3 was purchased from Guizhou Keyichuang Biotechnology Co., Ltd., model number: Soothing Essence YD.

[0030] Example 1 This embodiment provides an anti-dandruff shampoo containing selenium disulfide, comprising the following components: Selenium disulfide; Surfactant: a mixture of sodium laureth sulfate, ammonium lauryl sulfate and cocamidopropyl betaine, with a mass ratio of 12:3:5; Plant composition 1: a mixture of Bacillus fermentation product, Milo leaf or stem extract, p-hydroxyacetophenone and 1,2-pentanediol in a mass ratio of 1:0.3:0.3:0.1; Plant composition 2: a mixture of Centella asiatica extract and propylene glycol, with a mass ratio of 1:9; Plant composition 3: a mixture of Ceratonia suffruticosa fruit extract, hydrolyzed lupine protein, Sophora japonica flower extract, ethylhexylglycerin, 1,2-hexanediol, glycerol and water in a mass ratio of 1:0.9:1:0.1:1:25:21; essence; Preservative: Phenoxyethanol; Hair Conditioning Agent: Guar Hydroxypropyltrimonium Chloride; Chelating agent: disodium EDTA; pH adjuster: citric acid; Suspending agent: microcrystalline cellulose; Deionized water.

[0031] The above components are calculated by weight, specifically: 1.0 part of selenium disulfide; Surfactant: 20 parts; Plant composition 1: 3 parts; Plant composition 2: 2 parts; Plant composition 3: 1 part; Flavor: 0.5 parts; Preservatives: 0.5 parts; Hair conditioner: 0.4 parts; Chelating agent: 0.1 part; pH regulator: 0.2 parts; Suspension: 3 parts; 68.3 parts of deionized water.

[0032] The anti-dandruff shampoo containing selenium disulfide is specifically prepared in the following steps: S1: Add disodium EDTA, guar hydroxypropyltrimonium chloride, microcrystalline cellulose and deionized water into a stirring pot and stir well.

[0033] S2: Add sodium laureth sulfate, ammonium lauryl sulfate and cocamidopropyl betaine into a stirring pot, heat to 83-85℃ and stir to dissolve evenly.

[0034] S3: Cool down to below 40°C, add selenium disulfide and mix, stir and mix evenly.

[0035] S4: adding plant composition 1, plant composition 2, plant composition 3, essence, citric acid and preservative into a pot, stirring evenly, and discharging the materials to obtain the anti-dandruff shampoo containing selenium disulfide.

[0036] Example 2 Compared with Example 1, only the number of portions of each plant composition was changed, and the other components were the same as those in Example 1, specifically: Plant composition 1: 2 parts; Plant composition 2: 2 parts; Plant composition 3: 2 parts; The specific preparation steps of the anti-dandruff shampoo containing selenium disulfide are the same as those in Example 1.

[0037] Example 3 Compared with Example 1, only the number of portions of each plant composition was changed, and the other components were the same as those in Example 1, specifically: Plant composition 1: 1 part; Plant composition 2: 3 parts; Plant composition 3: 2 parts; The specific preparation steps of the anti-dandruff shampoo containing selenium disulfide are the same as those in Example 1.

[0038] Example 4 Compared with Example 1, only the number of portions of each plant composition was changed, and the other components were the same as those in Example 1, specifically: Plant composition 1: 1 part; Plant composition 2: 2 parts; Plant composition 3: 3 parts; The specific preparation steps of the anti-dandruff shampoo containing selenium disulfide are the same as those in Example 1.

[0039] Example 5 Compared with Example 1, only the number of portions of each plant composition was changed, and the other components were the same as those in Example 1, specifically: Plant composition 1: 2 parts; Plant composition 2: 1 part; Plant composition 3: 3 parts; The specific preparation steps of the anti-dandruff shampoo containing selenium disulfide are the same as those in Example 1.

[0040] Example 6 Compared with Example 1, only the number of portions of each plant composition was changed, and the other components were the same as those in Example 1, specifically: Plant composition 1: 3 parts; Plant composition 2: 1 part; Plant composition 3: 2 parts; The specific preparation steps of the anti-dandruff shampoo containing selenium disulfide are the same as those in Example 1.

[0041] Comparative Example 1 Compared with Example 2, plant composition 1 was removed, the number of portions of plant composition 2 was increased to 3 portions, the number of portions of plant composition 3 was increased to 3 portions, and the rest was the same as Example 2.

[0042] Comparative Example 2 Compared with Example 2, plant composition 2 was removed, the number of portions of plant composition 1 was increased to 3 portions, the number of portions of plant composition 3 was increased to 3 portions, and the rest was the same as Example 2.

[0043] Comparative Example 3 Compared with Example 2, plant composition 3 was removed, the number of portions of plant composition 1 was changed to 3 portions, the number of portions of plant composition 2 was changed to 3 portions, and the rest was the same as Example 2.

[0044] Comparative Example 4 Compared with Example 2, plant composition 1 was removed, and plant composition 2 was increased to 4 parts. The rest was the same as Example 2.

[0045] Comparative Example 5 Compared with Example 2, plant composition 2 was removed, and plant composition 1 was increased to 4 parts. The rest was the same as Example 2.

[0046] Comparative Example 6 Compared with Example 2, plant composition 3 was removed, plant composition 1 was increased to 4 parts, and the rest was the same as Example 2.

[0047] Comparative Example 7 Compared with Example 2, plant composition 3 was removed, and plant composition 2 was increased to 4 parts. The rest was the same as Example 2.

[0048] Comparative Example 8 Compared with Example 2, only the number of components is changed, as shown in Table 1.

[0049] The specific preparation steps of the anti-dandruff shampoo containing selenium disulfide are the same as those in Example 2.

[0050] Comparative Example 9 Compared with Example 2, only the number of components is changed, as shown in Table 1.

[0051] The specific preparation steps of the anti-dandruff shampoo containing selenium disulfide are the same as those in Example 2.

[0052] Table 1. Formulas of components of Examples 1 to 6 and Comparative Examples 1 to 7

[0053] Physical and chemical value testing (1) pH test Samples of the shampoos described in Examples 1 to 6 and Comparative Examples 1 to 9 were taken and measured with a pH meter, and the pH values ​​were found to be between 4 and 6.

[0054] (2) Viscosity test Samples of the shampoos described in Examples 1 to 6 and Comparative Examples 1 to 9 were taken, the sample temperature was adjusted to 25° C., and the samples were tested using a viscometer, and the viscosity values ​​were measured to be 6000-10000 mPa•s.

[0055] Stability test Samples of the shampoos described in Examples 1 to 6 and Comparative Examples 1 to 9 were packaged in transparent cosmetic bottles and placed at -15°C, 4°C, 25°C, and 45°C, respectively. The color, odor, and texture of the shampoos were examined for three months. The test results showed that no adverse conditions occurred during the test, indicating that the shampoos had good stability.

[0056] Efficacy test 1: in vitro antibacterial test Experimental object: An anti-dandruff shampoo containing selenium disulfide prepared in Examples 1 to 6 and Comparative Examples 1 to 9 was used as a test sample to conduct an antibacterial effect test.

[0057] Experimental method: The antibacterial effect was detected by the inhibition ring method: the culture medium used was agar culture medium, and the test strain was the standard strain of Malassezia furfur.

[0058] Experimental content: 1. Prepare Malassezia furfur into 10 5 CFU bacterial suspension. Apply evenly on Leeming & Notman medium plate, and then place it in a sterile operating table to dry the bacterial liquid on the plate.

[0059] 2. Add each shampoo sample to the above plate in a constant temperature incubator at 30°C. Observe the results after 5-7 days of cultivation and record the measurement of the inhibition rings.

[0060] Experimental results: The results are recorded as the diameter of the inhibition ring, unit: mm.

[0061] The results were determined according to the National Committee for Clinical Trials Standards (NCCLS) standard: the diameter of the inhibition zone <8 mm was insensitive, 8-13 mm was low sensitivity, 13-19 mm was moderate sensitivity, and >19 mm was highly sensitive. The test results are shown in Table 2.

[0062] Table 2. In vitro antibacterial test results

[0063] As can be seen from Table 2, the diameters of the antibacterial rings of Examples 1 to 6 and Comparative Examples 1 to 9 are all greater than 19 mm, indicating that the tested samples have significant antibacterial efficacy.

[0064] Efficacy Test 2: Human Patch Test Test object: The selenium disulfide-containing shampoos prepared in Examples 1 to 6 and Comparative Examples 1 to 9 were used as test samples for human body patch tests.

[0065] Subjects: 20 subjects, half male and half female, aged 20-55 years old, who met the voluntary selection criteria for subjects, were tested in the blank control group, embodiment group and comparative example group respectively.

[0066] Experimental method: Using a closed patch test, place an equal amount (0.020mL-0.025mL) of shampoo on the In a specific patch tester, apply it to the volunteer's arm with hypoallergenic tape and press lightly to make it evenly distributed. Apply the patch on the skin and leave it on for 24 hours; the blank control group is volunteers who do not use the product. After 24 hours, remove the patch Test the device, observe the skin reaction after 0.5h, 24h, and 48h, and record the results. The level of skin adverse reactions is as follows Table 3.

[0067] Table 3. Grades of skin adverse reactions

[0068] The results of the human patch test are shown in Table 4: Table 4. Human patch test results

[0069] It can be seen from Table 4 above that among the 20 subjects, there were no cases of adverse skin reactions in Examples 1 to 6, Comparative Examples 8 and 9, and there were several cases of Grade 1 adverse reactions in Comparative Examples 1 to 7. Comparative Examples 1 to 3 were based on Example 2 without a certain plant composition, and Comparative Examples 4 to 7 were based on Example 2 without a certain plant composition, while the content of another plant composition was increased, indicating that the three plant compositions are indispensable and have a synergistic soothing effect. The absence of any component will lead to a significant decrease in the effect.

[0070] Efficacy test 3: human sensory evaluation, transepidermal water loss rate test Test object: The selenium disulfide-containing shampoos prepared in Examples 1 to 6 and Comparative Examples 1 to 9 were used as test samples for human body patch tests.

[0071] Subjects: People with obvious dandruff were randomly selected as subjects, aged 18-45 years old, a total of 20 people, according to their personal washing habits, and the shampoo prepared in the embodiments of the present invention and the comparative example was used for testing after 14 days, and the test results were statistically taken as the average value of the subjects. The evaluation level was set as: 6-excellent, 5-good, 4-better, 3-average, 2-poor, 1-poor, a total of 6 levels, and the results are shown in Table 5.

[0072] Transepidermal water loss rate test method: On the first day, the subjects waited for 20 minutes at a temperature of 25±1℃ and a humidity of 40±10%, and then measured the transepidermal water loss rate of the arm about 10cm away from the palm (left and right hands are required to be random). After the test, the subjects took the samples home and used them every night. 14 days after use, the temperature was 25±1℃ and the humidity was 40±10%, and then waited for 20 minutes to measure the transepidermal water loss rate of the arm about 10cm away from the palm. German CK transepidermal water loss probe Tewameter TM300.

[0073] Table 5. Comprehensive table of user experience

[0074] It can be seen from Table 5 that, in general, Examples 1 to 6 have outstanding performance in terms of foam volume, fluffiness, soothing, antipruritic and anti-dandruff effects.

[0075] The transepidermal water loss rate of Example 1 to Example 6, Comparative Example 8 and Comparative Example 9 is significantly reduced, and the reduction rate of Comparative Example 1 to Comparative Example 7 is relatively small. Comparative Examples 1 to Comparative Examples 3 are based on Example 2 but one of the plant compositions is removed. Comparative Examples 4 to Comparative Examples 7 are based on Example 2 but one of the plant compositions is removed, and the content of another plant composition is increased, indicating that the three compositions have a good scalp moisturizing effect.

[0076] Example 1 to Example 6, Comparative Example 8 and Comparative Example 9 have relatively high soothing and antipruritic scores, while Comparative Example 1 to Comparative Example 7 have poor soothing and antipruritic effects. Comparative Examples 1 to Comparative Example 3 are based on Example 2 but one of the plant compositions is removed, and Comparative Examples 4 to Comparative Example 7 are based on Example 2 but one of the plant compositions is removed while increasing the content of another plant composition, indicating that the addition of the three plant compositions is helpful in soothing and antipruritic, and none of them can be missing.

[0077] The anti-dandruff scores of Examples 1 to 6 and Comparative Examples 1 to 7 are relatively high, while those of Comparative Examples 8 and 9 are relatively low. The amount of selenium sulfide used in Comparative Examples 8 and 9 is relatively low, indicating that selenium sulfide has a very good anti-dandruff effect. The larger the amount used, the more obvious the effect.

[0078] The above results show that the selenium disulfide shampoo with three plant compositions of the present invention not only effectively removes dandruff, but also has the effects of soothing, moisturizing and relieving itching, and solves the technical defects of using selenium disulfide as an anti-dandruff ingredient. The overall user satisfaction is high.

[0079] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present invention, rather than to limit the scope of protection of the present invention. Simple modifications or equivalent substitutions of the technical solution of the present invention by ordinary technicians in this field do not deviate from the essence and scope of the technical solution of the present invention.

Claims

1. An anti-dandruff shampoo containing selenium disulfide, characterized in that: By mass, it contains the following components: 0.05-2 parts of selenium disulfide, 10-40 parts of surfactant, 0.05-5 parts of plant composition 1, 0.05-5 parts of plant composition 2, 0.05-5 parts of plant composition 3, 0.05-1 part of preservative and 30-80 parts of water; The plant composition 1 comprises a Bacillus fermentation product and a Milo leaf or stem extract; The plant composition 2 comprises a Centella asiatica extract; The plant composition 3 comprises Ceratonia suffruticosa fruit extract, hydrolyzed lupin protein and Psoralea corylifolia flower extract.

2. The anti-dandruff shampoo according to claim 1, characterized in that By mass, it contains the following components: 0.5 parts to 1.5 parts of selenium disulfide, 15 parts to 30 parts of surfactant, 1 part to 4 parts of plant composition 1, 1 part to 4 parts of plant composition 2, 1 part to 4 parts of plant composition 3, 0.1 parts to 0.8 parts of preservative and 50 parts to 70 parts of water.

3. The anti-dandruff shampoo according to claim 2, characterized in that By mass, it contains the following components: 0.8-1 parts of selenium disulfide, 20-30 parts of surfactant, 1-3 parts of plant composition 1, 1-3 parts of plant composition 2, 1-3 parts of plant composition 3, 0.1-0.5 parts of preservative and 60-70 parts of water.

4. The anti-dandruff shampoo according to claim 1, characterized in that The plant composition 1 is a mixture of bacillus fermentation products, Milo leaf or stem extract, p-hydroxyacetophenone and 1,2-pentanediol.

5. The anti-dandruff shampoo according to claim 1, characterized in that The plant composition 2 is a mixture of Centella asiatica extract and propylene glycol.

6. The anti-dandruff shampoo according to claim 1, characterized in that The plant composition 3 is a mixture of carob fruit extract, hydrolyzed lupine protein, safflower flower extract, ethylhexylglycerin, 1,2-hexanediol, glycerin and water.

7. The anti-dandruff shampoo according to claim 1, characterized in that The mass ratio of the plant composition 1, the plant composition 2 and the plant composition 3 is 0.1-4:0.1-4:0.1-4.

8. The anti-dandruff shampoo according to claim 1, characterized in that The surfactant is selected from at least two of sodium laureth sulfate, ammonium lauryl sulfate, cocamidopropyl betaine, sodium methyl cocoyl taurate, disodium cocoyl glutamate and sodium lauroyl sarcosinate.

9. The anti-dandruff shampoo according to claim 1, characterized in that The preservative is selected from at least two of phenoxyethanol, potassium sorbate, kasone, iodopropynyl butylcarbamate, ethylhexylglycerin, glyceryl laurate, glyceryl caprylate, sodium benzoate, benzyl alcohol, and sodium salicylate.

10. The method for preparing an anti-dandruff shampoo containing selenium disulfide according to any one of claims 1 to 9, characterized in that: The following steps are involved: Step 1: Mix water and surfactant, raise the temperature to 80-85°C, and keep the temperature for 20-40 minutes to obtain mixture 1; Step 2: Stir the mixture 1 and cool it to below 40° C., add selenium disulfide, plant composition 1, plant composition 2, plant composition 3 and a preservative, and stir evenly to obtain an anti-dandruff shampoo containing selenium disulfide.

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