Gentiana scabra bunge anti-allergy soothing repairing agent and preparation method

By preparing gentian anti-allergic soothing and repairing agents containing a variety of medicinal extracts, the problems of insufficient active ingredients and insufficient repair of damaged skin are solved, and the effect of effectively allergic symptoms and repairing skin is achieved. It is suitable for sensitive skin, and the safety and effectiveness of the product is ensured through strict quality testing.

CN119606813AInactive Publication Date: 2025-03-14GUANGZHOU JINGPITANG COSMETICS CO LTD
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Patent Information

Application Number
CN202411847071.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-16
Publication Date
2025-03-14
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing skin anti-allergic products have problems such as low content of active ingredients, poor biological activity, and limited efficacy. At the same time, long-term use of traditional products may cause burden on the skin and neglect the repair effect on damaged skin.

Method used

Gentian anti-allergic soothing repair agents, including white fresh peel extract, scutellaria baicalensis extract, dandelion extract, honeysuckle extract, water Ganoderma lucidum extract and gentian extract, combined with propylene glycol, water, preservatives and emulsifiers, a stable emulsion is prepared through extraction, heating, stirring and emulsification steps.

Benefits of technology

This repair agent can not only effectively relieve allergic symptoms, reduce skin redness, swelling and itching, but also repair damaged skin, improve skin resistance, keep skin moisturized, and is suitable for sensitive skin. It also ensures the safety and effectiveness of the product through strict quality testing.

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Abstract

The invention discloses a radix gentianae anti-allergy soothing repairing agent and a preparation method thereof. In the invention, the cortex dictamni extract has an anti-allergic reaction effect, and can effectively inhibit mast cell degranulation and reduce release of inflammatory mediators such as histamine, so that symptoms such as pruritus, red and swollen, pain and the like caused by allergic reaction are relieved. The fructus kochiae extract, the radix scutellariae extract, the dandelion extract and the honeysuckle flower extract also have the effects of resisting inflammation, resisting allergy and the like, and allergy symptoms can be further relieved. The radix gentianae extract has the effects of clearing heat, drying dampness, purging fire and removing toxin and can improve the damp-heat state of skin and relieve allergy symptoms, and the multiple medicinal material extracts in the repairing agent all have a good relieving effect and can effectively relieve discomfort such as red and swollen skin and pruritus, so that the skin feels fresh, cool and comfortable. Meanwhile, the repairing agent also has the effect of repairing damaged skin, and can promote skin cell regeneration, repair damaged skin barrier, improve skin resistance and prevent repeated attack of allergic symptoms.
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Description

Technical Field

[0001] The present invention belongs to the technical field of biological medicines, and specifically relates to a gentian anti-allergic soothing repair agent and a preparation method thereof. Background Art

[0002] With the accelerated pace of life and the intensification of environmental pollution, more and more people are suffering from skin allergies. Skin allergies not only cause discomfort to patients, but may also affect their daily life and work. Traditional skin allergy products mostly rely on chemical synthetic ingredients. Although they can relieve allergic symptoms to a certain extent, long-term use may cause additional burden on the skin and even cause other skin problems.

[0003] Although the existing anti-allergic products made from plant extracts are relatively mild, they often have problems such as low content of active ingredients, weak biological activity, and limited efficacy. In addition, during the preparation process of these products, the control over the extraction process and the preservative system is not strict enough, which may lead to unstable product quality and questionable safety of use. In addition, anti-allergic products on the market often ignore the product's repairing effect on damaged skin, as well as its mildness and safety during use. People with sensitive skin have higher requirements for the ingredients and preparation process of the product. They need an anti-allergic product that can effectively relieve allergic symptoms, repair damaged skin, and is safe, gentle, and non-irritating. Summary of the invention

[0004] The purpose of the present invention is to provide a gentian anti-allergic soothing repair agent and a preparation method thereof in order to solve the above-mentioned problems.

[0005] The technical solution adopted by the present invention is as follows: a gentian anti-allergic soothing repair agent, the repair agent comprising a medicinal material extract, a matrix, a preservative and an emulsifier;

[0006] The medicinal material extracts include: 50-60 parts by weight of Dictamni cortex extract, 30-50 parts by weight of Kochia scoparia extract, 20-50 parts by weight of Scutellaria baicalensis extract, 20-50 parts by weight of Taraxacum officinale extract, 20-50 parts by weight of Honeysuckle extract, 10-50 parts by weight of Ganoderma lucidum extract and 25-50 parts by weight of Gentiana scabra extract:

[0007] The matrix comprises 200 parts by mass of propylene glycol and 400 parts by mass of water;

[0008] The preservatives include: 5 parts by mass of 1,2-hexanediol, 1 part by mass of phenoxyethanol, and 1 part by mass of ethylhexylglycerin;

[0009] The emulsifier was Tween-80: 20 parts by weight.

[0010] In a preferred embodiment, the preparation method comprises the following steps:

[0011] S1: Weigh: 50 parts by weight of Dictamni cortex extract, 30 parts by weight of Kochia scoparia extract, 20 parts by weight of Scutellaria baicalensis extract, 20 parts by weight of Taraxacum officinale extract, 20 parts by weight of Honeysuckle extract, 10 parts by weight of Ganoderma lucidum extract and 25 parts by weight of Gentiana scabra extract, mix the medicinal materials according to the proportion, perform reflux extraction with ethanol or water for multiple times, combine the extracts and concentrate under reduced pressure to the desired concentration;

[0012] S2: Prepare the matrix by heating propylene glycol and water to 70° C. and stirring evenly;

[0013] S3: adding the antiseptic system to the matrix and stirring evenly;

[0014] S4: adding the medicinal material extract to the matrix and stirring evenly;

[0015] S5: mixing the water phase and the oil phase, and emulsifying them with an emulsifier to form a stable emulsion;

[0016] S6: Cool the product to room temperature and stir evenly;

[0017] S7: Fill the product into a suitable container and seal it;

[0018] S8: Test the product, such as pH value, viscosity, microbial limit, etc., to ensure that the product quality meets the requirements;

[0019] S9: Package the product and attach a label with the product name, ingredients, instructions for use, production date and other information.

[0020] In a preferred embodiment, in step S2, propylene glycol: water is mixed in a ratio of 1:2, that is, 50 g propylene glycol and 100 g water. The mixture is heated to 70° C. to completely dissolve and stir evenly to obtain a transparent matrix solution.

[0021] In a preferred embodiment, in step S3, a magnetic stirrer is used for stirring, and the stirring speed is controlled at 300-500 rpm to ensure that the matrix solution is uniform. When adding the preservative system, a dropper or pipette can be used for quantitative addition to ensure the accuracy of the added amount.

[0022] In a preferred embodiment, in step S4, a magnetic stirrer is used for stirring, and the stirring speed is controlled at 600-700 rpm to ensure that the matrix solution is uniform. When adding the preservative system, a dropper or pipette is used for quantitative addition to ensure the accuracy of the added amount.

[0023] In a preferred embodiment, in step S5, the aqueous phase (herbal extract and preservative system) and the oil phase (propylene glycol and water) are mixed and emulsified using an emulsifier (Tween-80). The aqueous phase and the oil phase are heated to 70° C. respectively, and then slowly mixed and stirred continuously to form a stable emulsion. The emulsification process lasts for 10-20 minutes until the emulsion has a uniform and fine texture and drips in a pearly shape.

[0024] In a preferred embodiment, in step S6, the cooling process can last for 30-60 minutes, and a cooling water bath can be used to accelerate the cooling speed, and the cooling water temperature is controlled at 10-20° C. During the cooling process, ice cubes or ice water can be used to lower the cooling water temperature and accelerate the cooling speed.

[0025] In a preferred embodiment, in step S7, the cooled emulsion is filled into a clean container and sealed using a capping machine or a capping machine, and the sealing pressure is controlled at 0.5-1.0 MPa. During the filling process, a filling machine is used for automatic filling to ensure the accuracy of the filling amount.

[0026] In a preferred embodiment, in step S8, the pH value should be between 5.5 and 7.0, and can be measured using pH test paper or a pH meter. Viscosity can be measured using a viscometer and adjusted according to the product texture. Microbial limits should comply with relevant standards and can be tested using aseptic techniques, including plate counting, membrane filter, etc. During the test, attention should be paid to aseptic operation to avoid contamination.

[0027] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are:

[0028] 1. In the present invention, the Dictamni extract has an anti-allergic effect, can effectively inhibit mast cell degranulation, reduce the release of inflammatory mediators such as histamine, thereby alleviating symptoms such as itching, redness, and pain caused by allergic reactions. Kochia scoparia extract, Scutellaria baicalensis extract, Taraxacum extract and Honeysuckle extract also have anti-inflammatory and anti-allergic effects, which can further alleviate allergic symptoms. Gentiana scabra extract has the effects of clearing away heat and dampness, purging fire and detoxifying, can improve the damp and hot state of the skin, and alleviate allergic symptoms.

[0029] 2. In the present invention, the various medicinal extracts in the repair agent have good soothing effects, which can effectively relieve discomfort such as skin redness, swelling, itching, etc., and make the skin feel refreshed and comfortable. At the same time, the repair agent also has the effect of repairing damaged skin, which can promote skin cell regeneration, repair damaged skin barriers, improve skin resistance, and prevent recurrence of allergic symptoms. In addition, the moisturizing ingredients such as propylene glycol in the repair agent can replenish skin moisture, keep the skin moisturized, and improve problems such as dry and rough skin.

[0030] 3. In the present invention, the repair agent uses natural plant extracts, does not add irritating ingredients, has high safety, is suitable for all skin types, and is especially suitable for sensitive skin. At the same time, the repair agent has undergone strict quality testing and meets relevant standards, so it can be used with confidence. The repair agent uses the preparation method of biological drugs, with advanced extraction and purification processes, high content of effective ingredients, strong biological activity, and better efficacy. At the same time, the preparation method of biological drugs is adopted to ensure the effectiveness and safety of the product, providing more reliable protection and repair for sensitive skin. DETAILED DESCRIPTION

[0031] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0032] Embodiment 1:

[0033] Gentian anti-allergic soothing repair agent, the repair agent includes medicinal material extract, matrix, preservative and emulsifier;

[0034] The medicinal material extracts include: 50 parts by weight of Dictamni cortex extract, 30 parts by weight of Kochia scoparia extract, 20 parts by weight of Scutellaria baicalensis extract, 20 parts by weight of Taraxacum officinale extract, 20 parts by weight of Honeysuckle extract, 10 parts by weight of Ganoderma lucidum extract and 25 parts by weight of Gentiana scabra extract:

[0035] The matrix comprises 200 parts by mass of propylene glycol and 400 parts by mass of water;

[0036] The preservatives include: 5 parts by mass of 1,2-hexanediol, 1 part by mass of phenoxyethanol, and 1 part by mass of ethylhexylglycerin;

[0037] The emulsifier is Tween-80: 20 parts by weight;

[0038] The method comprises the following steps:

[0039] S1: Weigh: 50 parts by weight of Dictamni cortex extract, 30 parts by weight of Kochia scoparia extract, 20 parts by weight of Scutellaria baicalensis extract, 20 parts by weight of Taraxacum officinale extract, 20 parts by weight of Honeysuckle extract, 10 parts by weight of Ganoderma lucidum extract and 25 parts by weight of Gentiana scabra extract, mix the medicinal materials according to the proportion, perform reflux extraction with ethanol or water for multiple times, combine the extracts and concentrate under reduced pressure to the desired concentration;

[0040] S2: Prepare the matrix by heating propylene glycol and water to 70° C. and stirring evenly;

[0041] S3: adding the antiseptic system to the matrix and stirring evenly;

[0042] S4: adding the medicinal material extract to the matrix and stirring evenly;

[0043] S5: mixing the water phase and the oil phase, and emulsifying them with an emulsifier to form a stable emulsion;

[0044] S6: Cool the product to room temperature and stir evenly;

[0045] S7: Fill the product into a suitable container and seal it;

[0046] S8: Test the product, such as pH value, viscosity, microbial limit, etc., to ensure that the product quality meets the requirements;

[0047] S9: Package the product and attach a label with the product name, ingredients, instructions for use, production date and other information.

[0048] In step S1, a reflux extraction method is used to add the medicinal material extract and the solvent into an extraction device, heat to boiling, and maintain a slightly boiling state for a period of time to allow the active ingredients to be fully dissolved in the solvent. The extraction time can be adjusted according to the properties of the medicinal material and the content of the active ingredient, and generally 2-3 extractions are required.

[0049] In step S2, propylene glycol: water = 1:2, that is, 50 g propylene glycol and 100 g water, are mixed, and the mixture is heated to 70° C. to completely dissolve and stir evenly to obtain a transparent matrix solution.

[0050] In step S3, a magnetic stirrer is used for stirring, and the stirring speed is controlled at 300-500 rpm to ensure that the matrix solution is uniform. When adding the preservative system, a dropper or pipette can be used for quantitative addition to ensure the accuracy of the added amount.

[0051] In step S4, a magnetic stirrer is used for stirring, and the stirring speed is controlled at 600-700 rpm to ensure that the matrix solution is uniform. When adding the preservative system, a dropper or pipette is used for quantitative addition to ensure the accuracy of the added amount.

[0052] In step S5, the aqueous phase (herbal extract and preservative system) and the oil phase (propylene glycol and water) are mixed and emulsified using an emulsifier (Tween-80). The aqueous phase and the oil phase are heated to 70°C, then slowly mixed and stirred continuously to form a stable emulsion. The emulsification process lasts for 10-20 minutes until the emulsion has a uniform and fine texture and drips in a pearly shape.

[0053] In step S6, the cooling process can last for 30-60 minutes, and a cooling water bath can be used to accelerate the cooling speed, and the cooling water temperature is controlled at 10-20° C. During the cooling process, ice cubes or ice water can be used to reduce the cooling water temperature and accelerate the cooling speed.

[0054] In step S7, the cooled emulsion is filled into a clean container and sealed using a capping machine or a capping machine, and the sealing pressure is controlled at 0.5-1.0 MPa. During the filling process, a filling machine is used for automatic filling to ensure the accuracy of the filling amount.

[0055] In step S8, the pH value should be between 5.5-7.0 and can be measured using pH test paper or a pH meter. Viscosity can be measured using a viscometer and adjusted according to the product texture. Microbial limits should comply with relevant standards and can be tested using aseptic techniques, including plate counts, membrane filters, etc. During the test, attention should be paid to aseptic operation to avoid contamination.

[0056] In the present invention, the Dictamni extract has an anti-allergic effect, can effectively inhibit mast cell degranulation, reduce the release of inflammatory mediators such as histamine, and thus relieve symptoms such as itching, redness, and pain caused by allergic reactions. Kochia scoparia extract, Scutellaria baicalensis extract, Taraxacum extract, and Lonicera japonica extract also have anti-inflammatory and anti-allergic effects, and can further alleviate allergic symptoms. Gentiana scabra extract has the effects of clearing away heat and dampness, purging fire and detoxifying, and can improve the damp-heat state of the skin and alleviate allergic symptoms. .

[0057] In the present invention, the various medicinal extracts in the repair agent have good soothing effects, which can effectively relieve discomfort such as skin redness, swelling, itching, etc., and make the skin feel refreshed and comfortable. At the same time, the repair agent also has the effect of repairing damaged skin, which can promote skin cell regeneration, repair damaged skin barriers, improve skin resistance, and prevent allergic symptoms from recurring. In addition, moisturizing ingredients such as propylene glycol in the repair agent can replenish skin moisture, keep the skin moisturized, and improve problems such as dry and rough skin.

[0058] In the present invention, the repair agent adopts natural plant extracts, does not add irritating ingredients, has high safety, is suitable for various skin types, and is particularly suitable for sensitive skin. At the same time, the repair agent has undergone strict quality testing and meets relevant standards, and can be used with confidence. The repair agent adopts the preparation method of biological drugs, has advanced extraction and purification processes, high content of effective ingredients, strong biological activity, and better efficacy. At the same time, the preparation method of biological drugs is adopted to ensure the effectiveness and safety of the product, providing more reliable protection and repair for sensitive skin.

[0059] Embodiment 2:

[0060] Gentian anti-allergic soothing repair agent, the repair agent includes medicinal material extract, matrix, preservative and emulsifier;

[0061] The medicinal material extracts include: 60 parts by weight of Dictamni cortex extract, 50 parts by weight of Kochia scoparia extract, 50 parts by weight of Scutellaria baicalensis extract, 50 parts by weight of Taraxacum officinale extract, 50 parts by weight of Honeysuckle extract, 50 parts by weight of Ganoderma lucidum extract and 50 parts by weight of Gentiana scabra extract:

[0062] The matrix comprises 200 parts by mass of propylene glycol and 400 parts by mass of water;

[0063] The preservatives include: 5 parts by mass of 1,2-hexanediol, 1 part by mass of phenoxyethanol, and 1 part by mass of ethylhexylglycerin;

[0064] The emulsifier is Tween-80: 20 parts by weight;

[0065] The method comprises the following steps:

[0066] S1: Weigh: 50 parts by weight of Dictamni cortex extract, 30 parts by weight of Kochia scoparia extract, 20 parts by weight of Scutellaria baicalensis extract, 20 parts by weight of Taraxacum officinale extract, 20 parts by weight of Honeysuckle extract, 10 parts by weight of Ganoderma lucidum extract and 25 parts by weight of Gentiana scabra extract, mix the medicinal materials according to the proportion, perform reflux extraction with ethanol or water for multiple times, combine the extracts and concentrate under reduced pressure to the desired concentration;

[0067] S2: Prepare the matrix by heating propylene glycol and water to 70° C. and stirring evenly;

[0068] S3: adding the antiseptic system to the matrix and stirring evenly;

[0069] S4: adding the medicinal material extract to the matrix and stirring evenly;

[0070] S5: mixing the water phase and the oil phase, and emulsifying them with an emulsifier to form a stable emulsion;

[0071] S6: Cool the product to room temperature and stir evenly;

[0072] S7: Fill the product into a suitable container and seal it;

[0073] S8: Test the product, such as pH value, viscosity, microbial limit, etc., to ensure that the product quality meets the requirements;

[0074] S9: Package the product and attach a label with the product name, ingredients, instructions for use, production date and other information.

[0075] In step S1, a reflux extraction method is used to add the medicinal material extract and the solvent into an extraction device, heat to boiling, and maintain a slightly boiling state for a period of time to allow the active ingredients to be fully dissolved in the solvent. The extraction time can be adjusted according to the properties of the medicinal material and the content of the active ingredient, and generally 2-3 extractions are required.

[0076] In step S2, propylene glycol: water = 1:2, that is, 50 g propylene glycol and 100 g water, are mixed, and the mixture is heated to 70° C. to completely dissolve and stir evenly to obtain a transparent matrix solution.

[0077] In step S3, a magnetic stirrer is used for stirring, and the stirring speed is controlled at 300-500 rpm to ensure that the matrix solution is uniform. When adding the preservative system, a dropper or pipette can be used for quantitative addition to ensure the accuracy of the added amount.

[0078] In step S4, a magnetic stirrer is used for stirring, and the stirring speed is controlled at 600-700 rpm to ensure that the matrix solution is uniform. When adding the preservative system, a dropper or pipette is used for quantitative addition to ensure the accuracy of the added amount.

[0079] In step S5, the aqueous phase (herbal extract and preservative system) and the oil phase (propylene glycol and water) are mixed and emulsified using an emulsifier (Tween-80). The aqueous phase and the oil phase are heated to 70°C, then slowly mixed and stirred continuously to form a stable emulsion. The emulsification process lasts for 10-20 minutes until the emulsion has a uniform and fine texture and drips in a pearly shape.

[0080] In step S6, the cooling process can last for 30-60 minutes, and a cooling water bath can be used to accelerate the cooling speed, and the cooling water temperature is controlled at 10-20° C. During the cooling process, ice cubes or ice water can be used to reduce the cooling water temperature and accelerate the cooling speed.

[0081] In step S7, the cooled emulsion is filled into a clean container and sealed using a capping machine or a capping machine, and the sealing pressure is controlled at 0.5-1.0 MPa. During the filling process, a filling machine is used for automatic filling to ensure the accuracy of the filling amount.

[0082] In step S8, the pH value should be between 5.5-7.0 and can be measured using pH test paper or a pH meter. Viscosity can be measured using a viscometer and adjusted according to the product texture. Microbial limits should comply with relevant standards and can be tested using aseptic techniques, including plate counts, membrane filters, etc. During the test, attention should be paid to aseptic operation to avoid contamination.

[0083] In the present invention, the Dictamni extract has an anti-allergic effect, can effectively inhibit mast cell degranulation, reduce the release of inflammatory mediators such as histamine, and thus relieve symptoms such as itching, redness, and pain caused by allergic reactions. Kochia scoparia extract, Scutellaria baicalensis extract, Taraxacum extract, and Lonicera japonica extract also have anti-inflammatory and anti-allergic effects, and can further alleviate allergic symptoms. Gentiana scabra extract has the effects of clearing away heat and dampness, purging fire and detoxifying, and can improve the damp-heat state of the skin and alleviate allergic symptoms. .

[0084] In the present invention, the various medicinal extracts in the repair agent have good soothing effects, which can effectively relieve discomfort such as skin redness, swelling, itching, etc., and make the skin feel refreshed and comfortable. At the same time, the repair agent also has the effect of repairing damaged skin, which can promote skin cell regeneration, repair damaged skin barriers, improve skin resistance, and prevent allergic symptoms from recurring. In addition, moisturizing ingredients such as propylene glycol in the repair agent can replenish skin moisture, keep the skin moisturized, and improve problems such as dry and rough skin.

[0085] In the present invention, the repair agent adopts natural plant extracts, does not add irritating ingredients, has high safety, is suitable for various skin types, and is particularly suitable for sensitive skin. At the same time, the repair agent has undergone strict quality testing and meets relevant standards, and can be used with confidence. The repair agent adopts the preparation method of biological drugs, has advanced extraction and purification processes, high content of effective ingredients, strong biological activity, and better efficacy. At the same time, the preparation method of biological drugs is adopted to ensure the effectiveness and safety of the product, providing more reliable protection and repair for sensitive skin.

[0086] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0087] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. Gentian anti-allergic soothing repair agent, characterized by: The repair agent includes a medicinal material extract, a matrix, a preservative and an emulsifier; The medicinal material extracts include: 50-60 parts by weight of Dictamni cortex extract, 30-50 parts by weight of Kochia scoparia extract, 20-50 parts by weight of Scutellaria baicalensis extract, 20-50 parts by weight of Taraxacum officinale extract, 20-50 parts by weight of Honeysuckle extract, 10-50 parts by weight of Ganoderma lucidum extract and 25-50 parts by weight of Gentiana scabra extract: The matrix comprises 200 parts by mass of propylene glycol and 400 parts by mass of water; The preservatives include: 5 parts by mass of 1,2-hexanediol, 1 part by mass of phenoxyethanol, and 1 part by mass of ethylhexylglycerin; The emulsifier was Tween-80: 20 parts by weight.

2. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: The preparation method comprises the following steps: S1: Weigh: 50 parts by weight of Dictamni cortex extract, 30 parts by weight of Kochia scoparia extract, 20 parts by weight of Scutellaria baicalensis extract, 20 parts by weight of Taraxacum officinale extract, 20 parts by weight of Honeysuckle extract, 10 parts by weight of Ganoderma lucidum extract and 25 parts by weight of Gentiana scabra extract, mix the medicinal materials according to the proportion, perform reflux extraction with ethanol or water for multiple times, combine the extracts and concentrate under reduced pressure to the desired concentration; S2: Prepare the matrix by heating propylene glycol and water to 70° C. and stirring evenly; S3: adding the antiseptic system to the matrix and stirring evenly; S4: adding the medicinal material extract to the matrix and stirring evenly; S5: mixing the water phase and the oil phase, and emulsifying them with an emulsifier to form a stable emulsion; S6: Cool the product to room temperature and stir evenly; S7: Fill the product into a suitable container and seal it; S8: Test the product, including pH value, viscosity, and microbial limit, to ensure that the product quality meets the requirements; S9: Package the product and attach a label with the product name, ingredients, instructions for use, and production date.

3. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: In step S1, a reflux extraction method is used, wherein the medicinal material extract and a solvent are added to an extraction device, heated to boiling, and kept in a slightly boiling state for a period of time to allow the active ingredients to be fully dissolved in the solvent; the extraction time is adjusted according to the properties of the medicinal material and the content of the active ingredients, and generally 2-3 extractions are required.

4. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: In the step S2, propylene glycol: water is mixed in a ratio of 1:2, that is, 50 g of propylene glycol and 100 g of water; the mixture is heated to 70° C. to completely dissolve and stir evenly to obtain a transparent matrix solution.

5. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: In step S3, a magnetic stirrer is used for stirring, and the stirring speed is controlled at 300-500 rpm to ensure that the matrix solution is uniform. When adding the preservative system, a dropper or pipette is used for quantitative addition to ensure the accuracy of the added amount.

6. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: In step S4, a magnetic stirrer is used for stirring, and the stirring speed is controlled at 600-700 rpm to ensure that the matrix solution is uniform. When the preservative system is added, a dropper or pipette is used for quantitative addition to ensure the accuracy of the added amount.

7. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: In step S5, the aqueous phase medicinal material extract and the preservative system and the oil phase propylene glycol and water are mixed, and emulsified using an emulsifier Tween-80; the aqueous phase and the oil phase are heated to 70° C. respectively, and then slowly mixed and continuously stirred to form a stable emulsion; the emulsification process is continued for 10-20 minutes until the emulsion has a uniform and fine texture and drips in a pearl-like shape.

8. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: In step S6, the cooling process lasts for 30-60 minutes, and a cooling water bath is used to accelerate the cooling speed, and the cooling water temperature is controlled at 10-20° C. During the cooling process, ice cubes or ice water are used to lower the cooling water temperature and accelerate the cooling speed.

9. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: In step S7, the cooled emulsion is filled into a clean container and sealed using a capping machine or a capping machine, and the sealing pressure is controlled at 0.5-1.0 MPa; during the filling process, a filling machine is used for automatic filling to ensure the accuracy of the filling amount.

10. The method for preparing the gentian anti-allergic soothing repair agent according to claim 1, characterized in that: In step S8, the pH value should be between 5.5 and 7.0, and is measured using pH test paper or a pH meter; The viscosity is measured by a viscometer and adjusted according to the product texture; the microbial limit should comply with relevant standards and be tested using aseptic techniques, including plate counting method and membrane filter method; During the testing process, attention should be paid to aseptic operation to avoid contamination.