Traditional Chinese medicine preparation for treating diabetes and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for treating diabetes mellitus and a preparation method thereof.The preparation method comprises the following steps that biond magnolia flower, borneol, sandalwood, asarum, rhizoma atractylodis, astragalus membranaceus, Chinese yam and radix trichosanthis are weighed based on a preset proportion; pretreating the medicinal materials; the pretreated medicinal materials are treated; uniformly mixing the treated medicinal materials, putting into a decocting pot, adding a proper amount of clear water, boiling with big fire, and decocting with small fire; the decocted liquid medicine is filtered through a gauze net, and the traditional Chinese medicine preparation is obtained. Compared with side effects possibly accompanied by taking western medicines for a long time, the traditional Chinese medicine preparation possibly has lower side effect risk. The traditional Chinese medicines are generally known by natural components and mild action modes of the traditional Chinese medicines, so that adverse reactions such as hypoglycemia risk, weight gain and gastrointestinal discomfort are reduced, the compliance and life quality of patients are improved, and the problem of poor effect of an existing medicament treatment method is solved.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicines, and in particular to a traditional Chinese medicine preparation for treating diabetes and a preparation method thereof. Background Art

[0002] Diabetes is a common clinical endocrine metabolic disorder, characterized by high blood sugar, abnormal insulin secretion, and is easily accompanied by a variety of complications, which seriously hinder the daily life of diabetic patients. There are many types of diabetes. According to different pathogenesis, diabetes is divided into type 1 diabetes (Type 1 Diabetes Mellitus, T1DM), type 2 diabetes (Type 2 Mellitus, T2DM), gestational diabetes and special types of diabetes. Among them, type 2 diabetes (T2DM) patients account for 90% to 95%. The threat of diabetes is huge, therefore, the development of accurate and reliable diabetes detection reagents is crucial for the early detection and treatment of the disease.

[0003] At present, although Western medicine dominates the management and treatment strategies of diabetes, its treatment effect is often unsatisfactory in actual application. Even if many patients follow the doctor's advice and take hypoglycemic drugs on time, it is still difficult to achieve the ideal blood sugar control level. This limitation may be due to the complex pathophysiological mechanism of diabetes, including insulin secretion disorders, insulin resistance, and the resulting systemic metabolic disorders. Although Western medicine can regulate blood sugar to a certain extent, it is often difficult to fully cover the multiple pathogenesis of the disease, and long-term medication may be accompanied by side effects, such as the risk of hypoglycemia, weight gain, gastrointestinal discomfort, etc., which further affects the patient's compliance and quality of life. Summary of the invention

[0004] The purpose of the present invention is to provide a Chinese medicine preparation for treating diabetes and a preparation method thereof, aiming to solve the problem that the existing pharmaceutical treatment methods are not effective.

[0005] To achieve the above object, in a first aspect, the present invention provides a method for preparing a Chinese medicine preparation for treating diabetes, comprising the following steps:

[0006] Weigh magnolia, borneol, santalin, asarum, atractylodes, astragalus, yam and trichosanthes based on a preset ratio;

[0007] Pre-process the medicinal materials;

[0008] Processing the pre-treated medicinal materials;

[0009] Mix the processed herbs evenly and put them into the medicine decoction pot, add appropriate amount of water, boil over high heat and then simmer over low heat;

[0010] The decocted medicinal liquid is filtered through a gauze mesh to obtain a traditional Chinese medicine preparation.

[0011] Among them, in “weigh magnolia, borneol, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes based on the preset ratio”, the ratio is 10:9:8:7:11:30:20:15.

[0012] Among them, in "pre-processing medicinal materials", the following steps are included:

[0013] Clean and remove impurities from the symmetrically taken medicinal materials;

[0014] The cleaned medicinal materials are dried.

[0015] Among them, in "processing the pre-treated medicinal materials", the following steps are included:

[0016] Slice the dried medicinal materials;

[0017] The sliced ​​medicinal materials are crushed and ground.

[0018] Among them, in the step of "mixing the processed medicinal materials evenly and putting them into a decoction pot, adding an appropriate amount of clean water, boiling over high heat and then simmering over low heat", the ratio of water to medicinal materials is 1:5-10, and the simmering time over low heat is 0.5h-1.5h.

[0019] 6. The method for preparing a Chinese medicine preparation for treating diabetes as claimed in claim 5, characterized in that: in "filtering the decocted medicinal liquid through a gauze net to obtain a Chinese medicine preparation", the following steps are included:

[0020] Filter the decocted medicinal liquid through a gauze mesh to obtain a semi-finished medicinal liquid;

[0021] Concentrating the semi-finished liquid medicine to obtain a concentrated liquid;

[0022] The concentrated liquid is packaged to obtain a traditional Chinese medicine preparation.

[0023] In the second aspect, a Chinese medicine preparation for treating diabetes is prepared by the method for preparing a Chinese medicine preparation for treating diabetes as described in any one of claims 1-6, characterized in that it comprises magnolia, borneol, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes in a ratio of 10:9:8:7:11:30:20:15.

[0024] A method for preparing a Chinese medicine preparation for treating diabetes of the present invention comprises the following steps: weighing magnolia, borneol, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes root based on a preset ratio; pre-treating the medicinal materials; treating the pre-treated medicinal materials; mixing the treated medicinal materials evenly and putting them into a decoction pot, adding an appropriate amount of clean water, boiling over high heat and then decocting over low heat; filtering the decocted medicinal liquid through a gauze net to obtain a Chinese medicine preparation. Compared with the side effects that may be associated with long-term use of Western medicine, the Chinese medicine preparation of the present invention may have a lower risk of side effects. Chinese medicine is generally known for its natural ingredients and mild mode of action, which helps to reduce adverse reactions such as hypoglycemia risk, weight gain and gastrointestinal discomfort, thereby improving the compliance and quality of life of patients. This Chinese medicine preparation can comprehensively regulate the problems of insulin secretion disorders, insulin resistance and systemic metabolic disorders in diabetic patients through the synergistic effect of multiple medicinal materials. This comprehensive regulation method helps to improve the overall health of patients and may reduce the occurrence of complications. Thereby solving the problem of poor effect of existing pharmaceutical treatment methods. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0026] Figure 1 The present invention provides a flow chart of a method for preparing a traditional Chinese medicine preparation for treating diabetes.

[0027] Figure 2 It is a flow chart for pre-processing medicinal materials.

[0028] Figure 3 It is a flow chart for processing the pre-treated medicinal materials. DETAILED DESCRIPTION

[0029] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0030] See also Figures 1 to 3 In a first aspect, the present invention provides a method for preparing a Chinese medicine preparation for treating diabetes, comprising the following steps:

[0031] S1 weighs magnolia, borneol, santalin, asarum, atractylodes, astragalus, yam and trichosanthes based on a preset ratio;

[0032] The ratio is 10:9:8:7:11:30:20:15.

[0033] Specifically, first, accurately weigh each medicinal material according to the preset ratio of 10:9:8:7:11:30:20:15. This requires the use of precise weighing tools to ensure that the weight of each medicinal material is accurate. At the same time, attention should be paid to the storage method of volatile medicinal materials such as borneol to avoid losses during the weighing process.

[0034] S2 pre-treats the medicinal materials;

[0035] S21 washes and removes impurities from the symmetrically taken medicinal materials;

[0036] Specifically, the weighed magnolia, sandalwood, asarum, atractylodes, astragalus, yam and radix trichosanthis are placed in a cleaning tank and cleaned with clean water to remove dust, impurities and residual pesticides on the surface. The cleaning process should be gentle to avoid damaging the integrity of the medicinal materials. After cleaning, the medicinal materials are fished out and drained.

[0037] S22 dries the washed medicinal materials.

[0038] Specifically, put the cleaned medicinal materials into the dryer and set the appropriate temperature and time for drying. The drying temperature should not be too high to avoid destroying the effective ingredients of the medicinal materials. The drying time should be determined according to the water content of the medicinal materials and the performance of the dryer to ensure that the medicinal materials are completely dry for subsequent slicing and grinding.

[0039] S3 processes the pretreated medicinal materials;

[0040] S31 slices the dried medicinal materials;

[0041] Specifically, put the dried medicinal materials into the slicer, and adjust the blade spacing and slicing speed of the slicer according to the hardness and thickness requirements of the medicinal materials. The slicing process should be kept at a uniform speed to avoid the medicinal materials from breaking or uneven slicing. The sliced ​​medicinal materials should be neat and of uniform thickness to facilitate subsequent grinding.

[0042] S32 crushes and grinds the sliced ​​medicinal materials.

[0043] Specifically, the sliced ​​medicinal materials are placed in a grinder for crushing and grinding. During the grinding process, attention should be paid to controlling the speed and time of the grinder to avoid overheating or over-grinding of the medicinal materials. The ground medicinal materials should be in a fine powder form without a granular feel to ensure that the active ingredients are fully released when decocting the medicine.

[0044] S4: Mix the processed medicinal materials evenly and put them into a decoction pot, add an appropriate amount of water, boil them over high heat and then turn to low heat for decoction;

[0045] The ratio of water to medicinal materials is 1:5-10, and the decocting time on low heat is 0.5h-1.5h.

[0046] Specifically, mix the ground herbs evenly and put them into a decoction pot. According to the total amount of herbs and the capacity of the decoction pot, add an appropriate amount of water, and control the ratio between 1:5-10. Then, boil the liquid medicine over high heat, and then turn to low heat for decoction. The decoction time should be determined according to the ingredients and efficacy requirements of the herbs, generally between 0.5h-1.5h. Stir constantly during the decoction process to prevent the herbs from sticking to the pot or burning.

[0047] S5 filters the decocted medicinal liquid through a gauze mesh to obtain a Chinese medicine preparation.

[0048] Specifically, pour the decocted medicinal liquid into a filtering device and filter it using a gauze net. During the filtering process, gently squeeze the gauze net to allow the medicinal liquid to fully flow out, while preventing the medicinal material residue from entering the medicinal liquid. The filtered medicinal liquid should be clear and transparent, without impurities and sediments. Finally, the filtered medicinal liquid is placed in a clean container and sealed for storage to obtain a traditional Chinese medicine preparation.

[0049] First, accurately weigh each medicinal material according to the preset ratio of 10:9:8:7:11:30:20:15. This requires the use of precise weighing tools to ensure that the weight of each medicinal material is accurate. At the same time, attention should be paid to the storage method of volatile medicinal materials such as borneol to avoid losses during the weighing process. Put the weighed magnolia, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes into the cleaning tank and wash them with clean water to remove dust, impurities and residual pesticides on the surface. Be gentle during the cleaning process to avoid damaging the integrity of the medicinal materials. After cleaning, remove the medicinal materials and drain the water. Put the cleaned medicinal materials into the dryer and set the appropriate temperature and time for drying. The drying temperature should not be too high to avoid destroying the active ingredients of the medicinal materials. The drying time should be determined according to the water content of the medicinal materials and the performance of the dryer to ensure that the medicinal materials are completely dry for subsequent slicing and grinding. Put the dried medicinal materials into the slicer and adjust the blade spacing and slicing speed of the slicer according to the hardness and thickness requirements of the medicinal materials. The slicing process should be kept at a constant speed to avoid the crushing of medicinal materials or uneven slicing. The sliced ​​medicinal materials should be neat and of uniform thickness to facilitate subsequent grinding. Put the sliced ​​medicinal materials into the grinder for crushing and grinding. During the grinding process, pay attention to controlling the speed and time of the grinder to avoid overheating or over-grinding of the medicinal materials. The ground medicinal materials should be in a fine powder form without granularity to ensure the full release of the effective ingredients during decoction. Mix the ground medicinal materials evenly and put them into the decoction pot. According to the total amount of medicinal materials and the capacity of the decoction pot, add an appropriate amount of water, and control the ratio between 1:5-10. Then, boil the medicinal liquid over high heat, and then turn to low heat for decoction. The decoction time should be determined according to the composition and efficacy requirements of the medicinal materials, generally between 0.5h-1.5h. Stir constantly during the decoction process to avoid the medicinal materials sticking to the pot or burning. Pour the decoction into the filter device and filter it with a gauze net. During the filtration process, the gauze mesh should be gently squeezed to allow the liquid medicine to flow out fully, while preventing the residue of the medicinal materials from entering the liquid medicine. The filtered liquid medicine should be clear and transparent, without impurities and sediments. Finally, the filtered liquid medicine is placed in a clean container and sealed for storage to obtain a Chinese medicine preparation.

[0050] Example 1: Preparation of a Chinese medicine preparation for diabetes mellitus

[0051] Weighing medicinal materials: Use an electronic scale to accurately weigh magnolia, borneol, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes in the ratio of 10:9:8:7:11:30:20:15.

[0052] Washing of medicinal materials: Put the weighed magnolia, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes into the washing tank and wash gently with clean water to remove dust, impurities and pesticide residues. After washing, remove and drain.

[0053] Drying of medicinal materials: Put the cleaned medicinal materials into the dryer, set the temperature to 50℃, and the drying time to 4 hours to ensure that the medicinal materials are completely dry.

[0054] Medicinal material slicing: Put the dried medicinal materials into the slicer, adjust the blade spacing and slicing speed, and the medicinal materials will be neat and of uniform thickness after slicing.

[0055] Grinding of medicinal materials: Put the sliced ​​medicinal materials into the grinder, control the speed and time, and grind them into fine powder.

[0056] Decoction of medicinal liquid: Mix the ground medicinal materials evenly, put them into the decoction pot, and add 5 times the amount of water as the total amount of medicinal materials. Bring to a boil over high heat, then turn to low heat and simmer for 1 hour, stirring constantly.

[0057] Filtration of medicinal liquid: Pour the decocted medicinal liquid into the filtration device, filter it using a gauze mesh, and gently squeeze the gauze mesh to obtain a clear and transparent medicinal liquid.

[0058] Preservation of medicinal solution: put the filtered medicinal solution into a clean container, seal it and preserve it to obtain the Chinese medicine preparation.

[0059] Beneficial effects:

[0060] 1. The present invention accurately weighs magnolia, borneol, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes and prepares them according to a specific ratio of 10:9:8:7:11:30:20:15. The Chinese medicine preparation is intended to perform multi-dimensional regulation on the complex pathological mechanism of diabetes. This customized ratio helps to improve the treatment effect and better meet the personalized needs of patients.

[0061] Second, the medicinal materials of the present invention are subjected to pretreatment steps such as cleaning, drying, slicing and grinding, which not only removes impurities, but also makes the medicinal materials more delicate, which is conducive to the full release of effective ingredients during the decoction process. This refinement process can enhance the absorption efficiency of the drug and improve the therapeutic effect.

[0062] 3. The present invention controls the temperature and time during the decoction process and adds an appropriate amount of water, so that the preparation method can ensure that the active ingredients of the medicinal materials are stably released during the decoction process. This optimization process helps to reduce the loss of efficacy and improve the stability and reliability of traditional Chinese medicine preparations.

[0063] Fourth, the present invention filters the decocted liquid medicine through a gauze net to remove the residue and impurities of the medicinal materials, making the liquid medicine clearer and more transparent. This treatment method of improving the quality of the liquid medicine helps to enhance the patient's medication experience and also helps to improve the treatment effect.

[0064] In the second aspect, a Chinese medicine preparation for treating diabetes is prepared by the method for preparing a Chinese medicine preparation for treating diabetes as described in any one of claims 1-6, characterized in that it comprises magnolia, borneol, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes in a ratio of 10:9:8:7:11:30:20:15.

[0065] The above disclosure is only a preferred embodiment of a Chinese medicine preparation for treating diabetes and a preparation method of the present invention. Of course, this cannot be used to limit the scope of rights of the present invention. Ordinary technicians in this field can understand that all or part of the processes of the above embodiments and equivalent changes made according to the claims of the present invention still fall within the scope of the invention.

Claims

1. A method for preparing a Chinese medicine preparation for treating diabetes, characterized in that : Includes the following steps: Weigh magnolia, borneol, santalin, asarum, atractylodes, astragalus, yam and trichosanthes based on a preset ratio; Pre-process the medicinal materials; Processing the pre-treated medicinal materials; Mix the processed herbs evenly and put them into the medicine decoction pot, add appropriate amount of water, boil over high heat and then simmer over low heat; The decocted medicinal liquid is filtered through a gauze mesh to obtain a traditional Chinese medicine preparation.

2. The method for preparing a Chinese medicine preparation for treating diabetes as claimed in claim 1, characterized in that :In "weighing magnolia, borneol, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes based on the preset ratio", the ratio is 10:9:8:7:11:30:20:

15.

3. The method for preparing a Chinese medicine preparation for treating diabetes as claimed in claim 1, characterized in that : In "pre-processing medicinal materials", the following steps are included: Clean and remove impurities from the symmetrically taken medicinal materials; The cleaned medicinal materials are dried.

4. The method for preparing a Chinese medicine preparation for treating diabetes as claimed in claim 1, characterized in that : In "processing the pre-treated medicinal materials", the following steps are included: Slice the dried medicinal materials; The sliced ​​medicinal materials are crushed and ground.

5. The method for preparing a Chinese medicine preparation for treating diabetes as claimed in claim 1, characterized in that : In "mixing the processed medicinal materials evenly and putting them into a decoction pot, adding an appropriate amount of clean water, boiling over high heat and then decocting over low heat", the ratio of water to medicinal materials is 1:5-10, and the decocting time over low heat is 0.5h-1.5h.

6. The method for preparing a Chinese medicine preparation for treating diabetes as claimed in claim 1, characterized in that : In "filtering the decocted medicinal liquid through a gauze net to obtain a Chinese medicine preparation", the following steps are included: Filter the decocted medicinal liquid through a gauze mesh to obtain a semi-finished medicinal liquid; Concentrating the semi-finished liquid medicine to obtain a concentrated liquid; The concentrated liquid is packaged to obtain a traditional Chinese medicine preparation.

7. A Chinese medicine preparation for treating diabetes, prepared by the method for preparing a Chinese medicine preparation for treating diabetes according to any one of claims 1 to 6, characterized in that :Including magnolia, borneol, sandalwood, asarum, atractylodes, astragalus, yam and trichosanthes, in the ratio of 10:9:8:7:11:30:20:15.

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