Pathological cooling platform device based on Laval nozzle and use method thereof

Abstract

The invention discloses a pathological cooling platform device based on a Laval nozzle and a using method thereof, and the platform device comprises a pathological cooling storage platform and outer-layer heat insulation partition plates arranged on the front side, the rear side and the bottom side of the pathological cooling storage platform, a supersonic spray pipe and a heat conduction inner cavity are arranged between the pathological cooling storage platform and the outer-layer heat insulation partition plate, a high-pressure gas chamber is arranged on the upstream of the supersonic spray pipe, a front chamber pressure sensor is arranged in the high-pressure gas chamber, and a central wedge surface body is arranged in the middle of the high-pressure gas chamber and penetrates through a contraction section and a throat of the spray pipe. A supersonic velocity area pressure sensor is mounted on the wall surface of the expansion section at the downstream of the supersonic velocity spray pipe; and a temperature sensor is mounted in the heat conduction inner cavity. The cooling temperature of the pathological cooling storage platform can be accurately controlled, the cooling requirements of different pathological tissue samples are met, meanwhile, the Laval spray pipe is relatively simple in structure and easy to clean and maintain, and the use cost is reduced.

Description

Technical Field

[0001] The invention relates to a pathological cooling platform device based on a Rafale nozzle and a use method thereof. Background Art

[0002] Pathological diagnosis is an important part of medical diagnosis. It observes and analyzes tissue or cell samples obtained from the human body with the help of a microscope to determine the nature, cause, and pathogenesis of the disease. It first requires the human tissue or cell samples to be prepared into frozen pathological sections or paraffin pathological sections. The preparation process requires rapid freezing, and the prepared pathological sections are handed over to pathologists for diagnosis.

[0003] The present invention relates to a pathology cooling platform used in the preparation of pathology sections. It is a cooling device specially used for the preparation of pathology sections. Its main function is to quickly freeze tissue samples to a certain hardness, so as to facilitate the preparation of pathology microscopic sections after slicing, and to be read and diagnosed by a specialized pathologist under a microscope. This device is usually equipped with a refrigeration system and a temperature control system, which can accurately adjust the temperature to meet the freezing requirements of different tissue samples.

[0004] The working principle of the pathology cooling slice table mainly depends on its refrigeration system. The refrigeration system circulates the refrigerant through the compressor, condenser, evaporator and other components, thereby absorbing and releasing heat to achieve the purpose of lowering the temperature. In the process of making pathology slices, the tissue sample is placed on the cooling slice table, and the temperature control system is adjusted to quickly freeze the tissue sample to a suitable hardness. Then, the frozen tissue sample is sliced ​​using a slicer to obtain the required pathology slices. Summary of the invention

[0005] In order to overcome the shortcomings of the prior art such as complex system and slow refrigeration process, the present invention proposes a pathological cooling platform device based on a Lafayette nozzle and a method of using the same.

[0006] The technical solution adopted by the present invention to solve its technical problems is: a pathological cooling platform device based on a Rafale nozzle, including a pathological cooling storage platform and outer insulating baffles arranged on the front side, rear side and bottom side of the pathological cooling storage platform, a supersonic nozzle and a heat-conducting inner cavity are arranged between the pathological cooling storage platform and the outer insulating baffle, a high-pressure gas chamber is arranged upstream of the supersonic nozzle, a front chamber pressure sensor is arranged in the high-pressure gas chamber, a central wedge is arranged in the middle of the high-pressure gas chamber, the central wedge passes through the contraction section and throat of the nozzle, a supersonic zone pressure sensor is installed on the wall surface of the expansion section downstream of the supersonic nozzle, and a temperature sensor is installed in the heat-conducting inner cavity.

[0007] The present invention also provides a method for using a pathological cooling platform device based on a Rafale nozzle, comprising the following steps:

[0008] Step 1, connecting the supersonic pressure sensor, the inner cavity temperature sensor, the inner cavity liquid agitator, the front chamber pressure sensor, the high-pressure gas source and the motor to the computer respectively, connecting the high-pressure gas source to the high-pressure gas inlet of the high-pressure gas chamber, and connecting the motor to the central wedge-shaped body;

[0009] Step 2: Set the required cooling temperature of the storage platform on the computer, turn on the high-pressure gas source and the inner cavity liquid agitator through the computer, and the computer drives the motor to adjust the horizontal position of the central wedge according to the pressure signal fed back by the supersonic zone pressure sensor and the front chamber pressure sensor, thereby adjusting the throat area A of the Rafale nozzle. th , thereby changing the wall temperature T w ;

[0010] Step 3: The computer determines whether the storage platform has reached the set cooling temperature based on the temperature signal fed back by the inner cavity temperature sensor: if it has reached it, the relevant temperature value will be displayed and the operator will be instructed to place the pathological tissue on the storage platform for slicing; if it has not reached it, the computer will adjust the horizontal position of the central wedge in real time until the storage platform reaches the set cooling temperature.

[0011] Compared with the prior art, the present invention has the following positive effects:

[0012] The present invention uses the principle of aerodynamics to design a pathology cooling platform based on a Rafael nozzle, which is used to quickly freeze the wax blocks that have just been embedded, so that the paraffin and tissues solidify and are not easy to change their positions, so as to make the wax blocks faster and meet the needs of pathology sections. The specific advantages are as follows:

[0013] 1. Efficient cooling: The pathology cooling platform based on the Rafale nozzle can achieve fast and efficient cooling effect, which is suitable for rapid freezing and sectioning of pathological tissue samples.

[0014] 2. Precise temperature control: By changing the position of the central wedge, the working state of the Rafale nozzle can be adjusted, and the pressure of the upstream high-pressure gas source and other parameters can also be adjusted, ultimately achieving precise control of the cooling temperature to meet the cooling requirements of different pathological tissue samples.

[0015] 3. Energy saving and environmental protection: Compared with traditional cooling methods, the pathological cooling platform based on Rafale nozzle has higher energy efficiency ratio and lower energy consumption, while reducing pollution to the environment.

[0016] 4. Easy to maintain: The structure of the Rafale nozzle is relatively simple, easy to clean and maintain, and reduces the cost of use. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The present invention will be described by way of example with reference to the accompanying drawings, in which:

[0018] Figure 1 It is a schematic diagram of the structure of the platform device of the present invention;

[0019] Figure 2 is a side panel cross-sectional view of the platform device of the present invention;

[0020] Figure 3 is a three-dimensional exploded schematic diagram of the platform device of the present invention;

[0021] Figure 4 is a control schematic diagram of the platform device of the present invention;

[0022] Figure 5 It is a schematic diagram of the working principle of the platform device of the present invention;

[0023] Reference numerals in the figures include:

[0024] Pathological cooling storage platform 1, heat-conducting inner cavity 2, pathological tissue 3, outer insulation baffle 4, inner cavity insulation baffle 5, metal foam 6, supersonic airflow area 7, nozzle expansion section 8, supersonic area pressure sensor 9, inner cavity temperature sensor 10, inner cavity liquid agitator 11, high-pressure gas chamber 12, high-pressure gas inlet 13, front chamber pressure sensor 14, nozzle throat 15, central wedge 16, nozzle contraction section 17, flow direction of inner cavity heat-conducting liquid 18, flow direction of airflow in nozzle 19, computer 20, high-pressure gas source 21, and motor 22. DETAILED DESCRIPTION

[0025] A pathological cooling platform device based on a Rafale nozzle comprises: a pathological cooling storage platform 1, a heat-conducting inner cavity 2, a pathological tissue 3, an outer insulating baffle 4, an inner cavity insulating baffle 5, a metal foam 6, a supersonic airflow area 7, a nozzle expansion section 8, a supersonic area pressure sensor 9, an inner cavity temperature sensor 10, an inner cavity liquid agitator 11, a high-pressure gas chamber 12, a high-pressure gas inlet 13, a front chamber pressure sensor 14, a nozzle throat 15, a central wedge 16, a nozzle contraction section 17, a flow direction of the inner cavity heat-conducting liquid 18, a flow direction of the airflow in the nozzle 19, a computer 20, a high-pressure gas source 21, and a motor 22.

[0026] like Figure 1 to Figure 3As shown, the device is a rectangular parallelepiped, the upper layer is a pathological cooling and placing platform 1 made of metal with good thermal conductivity, on which the pathological tissue 3 to be operated is placed, and there are outer insulating baffles 4 on the front, back and bottom sides, which surround the supersonic nozzle and the heat-conducting inner cavity 2 in the middle. The upstream of the supersonic nozzle is a high-pressure gas chamber 12 and its inlet 13, and there is a front chamber pressure sensor 14 in the high-pressure gas chamber 12; the middle of the high-pressure gas chamber 12 is the central wedge 16 in the nozzle, which passes through the contraction section 17 and throat 15 of the nozzle, and the downstream is the expansion section 8 of the nozzle, on the wall of which a supersonic zone pressure sensor 9 is installed to measure the static pressure of the supersonic airflow area 7. The expansion section 8 is a low-temperature supersonic airflow area 7, which is surrounded by the heat-conducting inner cavity 2 on all sides. The heat-conducting inner cavity 2 itself is closed and filled with a liquid with good thermal conductivity, and a temperature sensor 10 and a stirrer 11 are installed therein. There are heat-insulating baffles 5 of the inner cavity on both the upstream and downstream sides of the heat-conducting inner cavity 2. Metal foam 6 is installed downstream of the supersonic airflow area 7, from which the airflow is discharged to the surrounding environment.

[0027] Working principle of cooling the Rafale nozzle of the present invention

[0028] The variable throat Rafale nozzle based on the center wedge of the present invention changes the cross section of the throat 15 of the nozzle by the translation of the center wedge body 16, thereby adjusting the downstream supersonic outlet cross section and the throat area ratio, and finally adjusting the Mach number of the downstream ultrasonic flow field, and then changing the downstream wall temperature by changing the Mach number. The wall temperature is rapidly reduced to below the freezing point, and the cold energy is transferred to the storage platform 1 through the surrounding heat-conducting inner cavity 2, so that the pathological tissue 3 is rapidly frozen.

[0029] like Figure 5 As shown, for the Lafayette nozzle, its upstream is the contraction section 17 curve, and the downstream is the expansion section 8 curve. The place with the smallest cross-sectional area in the middle is called the nozzle throat 15. According to the relevant knowledge of aerodynamics, when the high-pressure gas with the upstream total pressure P0 and total temperature T0 flows through the nozzle, the throat reaches the speed of sound, and the flow is supersonic when the downstream continues to expand. The flow Mach number M is calculated according to the local area A and the throat area A. th , satisfying the following relationship:

[0030]

[0031] Furthermore, the local static temperature T and the total temperature of the incoming flow T0 satisfy the following isentropic relationship:

[0032]

[0033] At this time, the wall temperature T w It can be calculated according to the following empirical formula:

[0034]

[0035] Where Pr t is the Prandtl number of the turbulent boundary layer of the nozzle, usually 0.6 to 0.8.

[0036] When the wedge 16 in the upstream convergence section of the nozzle moves to the right, the throat area A th Under the condition of isentropic and no shock wave, according to formula (1), the Mach number M of the downstream will increase significantly. Since the total temperature T0 of the high-pressure gas source is usually about room temperature 300K, according to formula (2), the static temperature T in the supersonic airflow area 7 will drop rapidly. At this time, the temperature T of the supersonic wall w It can be estimated by formula (3).

[0037] Working process of the platform device of the present invention

[0038] like Figure 4 As shown, first, the cooling temperature of the platform is set on the computer 20, and the high-pressure gas source 21 and the stirrer 11 are turned on by the computer 20. The computer will drive the motor 22 to adjust the horizontal position of the central wedge body and the working state of the Rafale nozzle according to the feedback pressure signal of the supersonic zone pressure sensor 9 and the front chamber pressure sensor 14, thereby changing the wall temperature. The computer determines whether the storage platform 1 has reached the specified temperature according to the feedback signal of the temperature sensor 10 of the inner cavity.

[0039] If the temperature reaches the specified value, the relevant temperature signal will be fed back to the computer and instruct the operator to place the pathological tissue on the cooling table for slicing. If the temperature deviates from the specified temperature, the computer will adjust the position of the high-pressure gas source 21 and the central wedge 16 in real time to adjust the working state of the Rafale nozzle.

Claims

1. A pathological cooling platform device based on a Rafale nozzle, characterized in that: The invention comprises a pathological cooling storage platform and outer insulating baffles arranged on the front side, the rear side and the bottom side of the pathological cooling storage platform, a supersonic nozzle and a heat-conducting inner cavity are arranged between the pathological cooling storage platform and the outer insulating baffle, a high-pressure gas chamber is arranged upstream of the supersonic nozzle, a front chamber pressure sensor is arranged in the high-pressure gas chamber, a central wedge is arranged in the middle of the high-pressure gas chamber, the central wedge passes through the contraction section and the throat of the nozzle, a supersonic zone pressure sensor is installed on the wall surface of the expansion section downstream of the supersonic nozzle, and a temperature sensor is installed in the heat-conducting inner cavity.

2. A pathological cooling platform device based on a Rafale nozzle according to claim 1, characterized in that: Inner cavity heat insulation baffles are arranged on both upstream and downstream sides of the heat-conducting inner cavity.

3. A pathological cooling platform device based on a Rafale nozzle according to claim 1, characterized in that: The heat-conducting inner cavity is a closed cavity.

4. A pathological cooling platform device based on a Rafale nozzle according to claim 3, characterized in that: The heat-conducting inner cavity is filled with liquid with good heat-conducting performance.

5. A pathological cooling platform device based on a Rafale nozzle according to claim 4, characterized in that: A stirrer is installed in the heat-conducting inner cavity.

6. The pathological cooling platform device based on the Rafale nozzle according to claim 1, characterized in that: The expansion section downstream of the supersonic nozzle is the supersonic airflow zone.

7. A pathological cooling platform device based on a Rafale nozzle according to claim 6, characterized in that: Metal foam is installed downstream of the supersonic flow region.

8. The pathological cooling platform device based on the Rafale nozzle according to claim 7, characterized in that: The heat-conducting inner cavity surrounds the supersonic airflow area.

9. The pathological cooling platform device based on the Rafale nozzle according to claim 1, characterized in that: The supersonic zone pressure sensor, the inner cavity temperature sensor and the front chamber pressure sensor are respectively connected to the computer, the computer is respectively connected to the high-pressure gas source and the motor, the high-pressure gas source is connected to the high-pressure gas inlet of the high-pressure gas chamber, and the motor is connected to the central wedge.

10. A method for using the pathological cooling platform device according to claim 1, characterized in that: The steps include: Step 1, connecting the supersonic pressure sensor, the inner cavity temperature sensor, the inner cavity liquid agitator, the front chamber pressure sensor, the high-pressure gas source and the motor to the computer respectively, connecting the high-pressure gas source to the high-pressure gas inlet of the high-pressure gas chamber, and connecting the motor to the central wedge-shaped body; Step 2: Set the required cooling temperature of the storage platform on the computer, turn on the high-pressure gas source and the inner cavity liquid agitator through the computer, and the computer drives the motor to adjust the horizontal position of the central wedge according to the pressure signal fed back by the supersonic zone pressure sensor and the front chamber pressure sensor, thereby adjusting the throat area A of the Rafale nozzle. th , thereby changing the wall temperature T w ; Step 3: The computer determines whether the storage platform has reached the set cooling temperature based on the temperature signal fed back by the inner cavity temperature sensor: if it has reached it, the relevant temperature value will be displayed and the operator will be instructed to place the pathological tissue on the storage platform for slicing; if it has not reached it, the computer will adjust the horizontal position of the central wedge in real time until the storage platform reaches the set cooling temperature.

Images