Pipetting replacement structure for chemiluminescence tester

Abstract

The invention discloses a pipetting replacement structure for a chemiluminescence determinator, and relates to the technical field of chemiluminescence determination.The pipetting replacement structure comprises a pipetting cylinder and further comprises a cleaning mechanism arranged on the pipetting cylinder through a connecting base and used for cleaning waste liquid generated after pipetting in the pipetting cylinder; the cleaning mechanism comprises a reagent box for storing cleaning liquid, a connecting pipe is arranged on the reagent box, a conveying pump is arranged between the reagent box and the connecting pipe, and a reciprocating assembly, a driving assembly for driving the reciprocating assembly to move and a resetting assembly capable of resetting the reciprocating assembly are installed on the conveying pump. After the liquid is replaced and moved, the cleaning solution is accurately sprayed into the liquid moving cylinder, and is driven by the water wheel blades, so that the rotary wiping of the wiping assembly is realized, residues on the inner wall of the liquid moving cylinder are ensured to be thoroughly removed, the potential influence of the last liquid moving on the subsequent determination is avoided, the error of the chemiluminescence tester caused by solution pollution is obviously reduced, and the accuracy of the chemiluminescence tester is improved. Therefore, the accuracy and the reliability of measurement are improved.

Description

Technical Field

[0001] The invention belongs to the technical field of chemiluminescence determination, in particular to a liquid transfer replacement structure for a chemiluminescence determination instrument. Background Art

[0002] In the use of chemiluminescence analyzers, the pipette cylinder is a key component. Its internal cleanliness is directly related to the accuracy and reliability of the measurement results, and it is often used in conjunction with machinery.

[0003] However, the existing pipetting replacement structure will leave residual solution from the previous pipetting after changing the pipetting, causing the residue from the previous pipetting to have a potential impact on subsequent measurements, thereby causing measurement errors. It lacks automation and has poor continuity, which affects the measurement operation of the chemiluminescence analyzer. Therefore, a pipetting replacement structure for a chemiluminescence analyzer is proposed. Summary of the invention

[0004] In order to solve the problems raised by the above background technology, the present invention proposes a liquid transfer replacement structure for a chemiluminescence measuring instrument.

[0005] The purpose of the present invention can be achieved through the following technical solutions:

[0006] A liquid transfer replacement structure for a chemiluminescence measuring instrument, comprising a liquid transfer cylinder and a cleaning mechanism, which is arranged on the liquid transfer cylinder through a connecting seat and is used to clean the waste liquid after liquid transfer in the liquid transfer cylinder;

[0007] The cleaning mechanism comprises a reagent box for storing cleaning liquid, a connecting pipe is arranged on the reagent box, a delivery pump is arranged between the reagent box and the connecting pipe, a reciprocating component and a driving component for driving the reciprocating component to move and a resetting component capable of resetting the reciprocating component are installed on the delivery pump, and a wiping component for wiping the inner wall of the pipette tube is installed on the reciprocating component;

[0008] The replacement mechanism is arranged on the pipette and is used to replace the wiping component inside the pipette after it has been used.

[0009] As a further preferred embodiment of the present technical solution: the reciprocating assembly includes a No. 1 connecting rod, the No. 1 connecting rod is rotatably connected to a No. 2 connecting rod, the No. 2 connecting rod is rotatably connected to a connecting block, and the lower end of the connecting block is rotatably connected to a screw rod.

[0010] As a further preferred embodiment of the present technical solution: the driving assembly includes a transmission shaft, and the interior of the connecting pipe is fixedly connected to a No. 1 fixing frame, and the transmission shaft is rotatably connected to the No. 1 fixing frame, one end of the transmission shaft is fixedly connected to a water wheel blade, and the other end of the transmission shaft is fixedly connected to a No. 1 bevel gear, the No. 1 bevel gear is meshed with a No. 2 bevel gear, the interior of the No. 2 bevel gear is fixedly connected to a rotating shaft, the rotating shaft is rotatably connected to the connecting pipe, and the rotating shaft is fixedly connected to a No. 1 connecting rod.

[0011] As a further preferred embodiment of the present technical solution: the lower end of the screw rod is fixedly connected to an electric suction cup, a suction head is provided on the electric suction cup, and a No. 1 connecting frame is fixedly connected to the outer shell of the electric suction cup, and a T-shaped limit block is fixedly connected to the lower end of the No. 1 connecting frame.

[0012] As a further preferred embodiment of the present technical solution: a wiping assembly is arranged below the suction head, a symmetrically arranged guide groove is arranged on the wiping assembly, a sliding groove is arranged on the upper surface of the wiping assembly, and the sliding groove and the T-shaped limit block are slidably arranged.

[0013] As a further preferred embodiment of the present technical solution: the reset assembly includes a No. 2 fixed frame fixedly connected to the connecting seat, two sliding shafts are fixedly connected to the No. 2 fixed frame, an iron block is slidably connected to the sliding shaft, and a reset spring is sleeved on the outer side of the sliding shaft, the reset spring is arranged between the connecting seat and the iron block, an electromagnet is arranged on the No. 2 fixed frame, and the electromagnet is magnetically connected to the iron block, and the iron block is fixedly connected to the connecting block.

[0014] As a further preferred embodiment of the technical solution: a No. 2 connecting frame is fixedly connected to the connecting seat, a threaded sleeve is fixedly connected to the No. 2 connecting frame, and the threaded sleeve is threadedly connected to the screw rod.

[0015] As a further preferred embodiment of the present technical solution: the replacement mechanism includes a replacement groove fixedly connected to the pipette cylinder, the replacement groove is provided with a guide rod, and the guide rod is slidably connected to the guide groove on the wiping assembly, the replacement groove is provided with a replacement inlet for delivering the wiping assembly into the pipette cylinder, the replacement groove is fixedly connected to a No. 3 fixing frame, the No. 3 fixing frame is fixedly connected to a cylinder, the output end of the cylinder is fixedly connected to a push block, and the push block is slidably connected to a slide groove on the wiping assembly.

[0016] As a further preferred embodiment of the technical solution: a liquid inlet tube is provided through the pipette cylinder, and a replacement outlet is provided on the pipette cylinder.

[0017] As a further preferred embodiment of the technical solution: a sensor is provided on the second fixing bracket, and a controller is provided on the connecting seat.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] 1. In the present invention, after changing the pipette, the cleaning solution is accurately sprayed into the interior of the pipette tube, and the water wheel blades drive the wiping component to realize the rotational wiping, ensuring that the residue on the inner wall of the pipette tube is completely removed, avoiding the potential impact of the previous pipetting on subsequent measurements, and significantly reducing the error caused by solution contamination in the chemiluminescence analyzer, thereby improving the accuracy and reliability of the measurement.

[0020] 2. In the present invention, the connection block is reset by the reset component, creating conditions for loading a new wiping component into the interior of the pipette, ensuring that the pipette can be replaced with a clean wiping component in time after each use, thereby avoiding measurement errors caused by aging or contamination of the wiping component.

[0021] 3. In the present invention, the replacement mechanism is used to ensure stable loading and positioning of the wiping assembly. The cylinder pushes the wiping assembly at the bottom layer in the replacement groove into the interior of the pipette tube. At the same time, the T-shaped limit block ensures that the wiping assembly will not fall during replacement. The setting of the guide rod ensures that the sliding groove and the T-shaped limit block of the wiping assembly are aligned during the loading process, thereby avoiding the problem of misalignment of the wiping assembly. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0023] Figure 2 It is a partial structural cross-sectional view of the present invention;

[0024] Figure 3 for Figure 2 The enlarged schematic diagram at A in the middle;

[0025] Figure 4 It is a schematic diagram of the local three-dimensional structure of the present invention Figure 1 ;

[0026] Figure 5 It is a schematic diagram of the local three-dimensional structure of the present invention Figure 2 ;

[0027] Figure 6 It is a schematic diagram of the local three-dimensional structure of the present invention Figure 3 ;

[0028] Figure 7 It is a schematic diagram of the local three-dimensional structure of the present invention Figure 4 .

[0029] Legend: 1. Pipette; 11. Liquid inlet tube; 12. Replacement outlet; 2. Connecting seat; 3. Cleaning mechanism; 31. Reagent box; 32. Connecting pipe; 33. Delivery pump; 34. No. 1 fixing frame; 35. Water wheel blade; 351. Transmission shaft; 352. No. 1 bevel gear; 353. No. 2 bevel gear; 354. Rotating shaft; 36. No. 1 connecting rod; 361. No. 2 connecting rod; 362. Connecting block; 363. Screw rod; 37. Electric suction cup; 38. Suction head; 39. No. 1 No. 1 connecting frame; 310, T-shaped limit block; 311, No. 2 fixing frame; 3111, sliding shaft; 3112, return spring; 3113, electromagnet; 3114, iron block; 312, sensor; 313, controller; 314, No. 2 connecting frame; 315, threaded sleeve; 316, liquid filling port; 4, wiping assembly; 41, slide groove; 42, guide groove; 5, replacement groove; 51, guide rod; 52, replacement entrance; 53, No. 3 fixing frame; 54, cylinder; 55, push block. DETAILED DESCRIPTION

[0030] The technical solution of the present invention will be clearly and completely described below in conjunction with the embodiments. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] Embodiment 1:

[0032] See also Figure 1-Figure 7 The present application provides a pipetting replacement structure for a chemiluminescence measuring instrument, comprising a pipetting cylinder 1, and also comprising a cleaning mechanism 3, which is arranged on the pipetting cylinder 1 through a connecting seat 2 and is used to clean the waste liquid after pipetting inside the pipetting cylinder 1; the cleaning mechanism 3 comprises a reagent box 31 for storing cleaning liquid, and the reagent box 31 is provided with a liquid injection port 316, wherein the liquid injection port 316 is used to supplement the cleaning solution, and a connecting tube 32 is provided on the reagent box 31, and a delivery pump 33 is provided between the reagent box 31 and the connecting tube 32, and a reciprocating component and a driving component for driving the reciprocating component to move and a resetting component capable of resetting the reciprocating component are installed on the delivery pump 33, and a wiping component 4 for wiping the inner wall of the pipetting cylinder 1 is installed on the reciprocating component; wherein the wiping component 4 comprises a shell and a wiping block that can be adsorbed by a suction head 38, and a replacement mechanism is provided on the pipetting cylinder 1, for replacing the wiping component 4 inside the pipetting cylinder 1 after use.

[0033] In this embodiment, the reciprocating assembly includes a No. 1 connecting rod 36 , which is rotatably connected to a No. 2 connecting rod 361 , which is rotatably connected to a connecting block 362 , and a screw rod 363 is rotatably connected to the lower end of the connecting block 362 .

[0034] Specifically, connecting rod No. 1 36 drives connecting rod No. 2 361 to rotate, connecting rod No. 2 361 drives screw rod 363 to move up and down, screw rod 363 is rotated by threaded sleeve 315, screw rod 363 drives electric suction cup 37 to rotate, electric suction cup 37 drives wiping component 4 sucked by suction head 38 to rotate and cooperate with the cleaning solution sprayed from reagent box 31 to wipe the inner wall of pipette tube 1, so that the pipette tube 1 after replacement of pipetting is wiped, avoiding the problem that the pipette tube 1 after replacement of pipetting is affected by the previous pipetting, resulting in the solution detected by the chemiluminescence analyzer being contaminated.

[0035] In this embodiment, the driving assembly includes a transmission shaft 351, and the interior of the connecting tube 32 is fixedly connected to a No. 1 fixing frame 34, and the transmission shaft 351 is rotatably connected to the No. 1 fixing frame 34, one end of the transmission shaft 351 is fixedly connected to a water wheel blade 35, and the other end of the transmission shaft 351 is fixedly connected to a No. 1 bevel gear 352, the No. 1 bevel gear 352 is meshed with a No. 2 bevel gear 353, and the interior of the No. 2 bevel gear 353 is fixedly connected to a rotating shaft 354, the rotating shaft 354 is rotatably connected to the connecting tube 32, and the rotating shaft 354 is fixedly connected to a No. 1 connecting rod 36.

[0036] Specifically, by starting the delivery pump 33, the cleaning solution inside the reagent box 31 is sprayed from the inside of the reagent box 31 into the inside of the pipette tube 1. When the cleaning solution flows through the inside of the connecting tube 32, the liquid impacts the water wheel blades 35 to rotate, the water wheel blades 35 drive the transmission shaft 351 to rotate, the transmission shaft 351 drives the first bevel gear 352 to rotate, the first bevel gear 352 drives the second bevel gear 353 to rotate, the second bevel gear 353 drives the rotating shaft 354 to rotate, and the rotating shaft 354 drives the first connecting rod 36 to rotate.

[0037] In this embodiment, a second connecting frame 314 is fixedly connected to the connecting seat 2 , a threaded sleeve 315 is fixedly connected to the second connecting frame 314 , and the threaded sleeve 315 is threadedly connected to the screw rod 363 .

[0038] During the up and down reciprocating motion of the screw rod 363 , the screw rod 363 drives the wiping assembly 4 sucked by the suction head 38 below to rotate through the threaded sleeve 315 to clean the inner wall of the pipette tube 1 .

[0039] The pipette 1 is provided with a liquid inlet tube 11 for connecting with an external liquid suction pump to suck liquid into the interior of the pipette 1 , and the pipette 1 is provided with a replacement outlet 12 to facilitate taking out the replaced wiping component 4 from the interior of 1 .

[0040] Embodiment 2:

[0041] On the basis of embodiment one, the reset assembly includes a No. 2 fixed frame 311 fixedly connected to the connecting seat 2, two sliding shafts 3111 are fixedly connected to the No. 2 fixed frame 311, an iron block 3114 is slidably connected to the sliding shaft 3111, and a reset spring 3112 is sleeved on the outer side of the sliding shaft 3111, the reset spring 3112 is arranged between the connecting seat 2 and the iron block 3114, an electromagnet 3113 is arranged on the No. 2 fixed frame 311, and the electromagnet 3113 is magnetically connected to the iron block 3114, and the iron block 3114 is fixedly connected to the connecting block 362.

[0042] Specifically, the iron block 3114 rises under the action of magnetic force, so that the iron block 3114 drives the connecting block 362 to reset. The setting of the reset spring 3112 can reduce the resistance of the connecting block 362 to rise. The reset of 362 facilitates the loading of the new wiping component 4 inside the replacement slot 5 into the interior of the pipette cylinder 1.

[0043] In this embodiment, a sensor 312 is provided on the second fixing frame 311, and a controller 313 is provided on the connecting seat 2. It should be noted that the controller 313 controls the electromagnet 3113 to be energized through the sensor 312, which is a prior art technology and is only used without describing its control process.

[0044] Embodiment three:

[0045] On the basis of embodiment one, the replacement mechanism includes a replacement groove 5 fixedly connected to the pipette cylinder 1, and a guide rod 51 is provided on the replacement groove 5, wherein the guide rod 51 is provided for the purpose of being used in conjunction with the guide groove 42, so that when filling the wiping assembly 4, the slide groove 41 on the wiping assembly 4 is always aligned with the T-shaped limit block 310, and the guide rod 51 is slidably connected to the guide groove 42 on the wiping assembly 4, and a replacement entrance 52 for sending the wiping assembly 4 into the pipette cylinder 1 is provided on the replacement groove 5, a No. 3 fixing frame 53 is fixedly connected to the replacement groove 5, and a cylinder 54 is fixedly connected to the No. 3 fixing frame 53, and a push block 55 is fixedly connected to the output end of the cylinder 54, and the push block 55 is slidably connected to the slide groove 41 on the wiping assembly 4.

[0046] Specifically, the air cylinder 54 is started to drive the push block 55 to push the wiping assembly 4 at the bottom layer inside the replacement groove 5 from the replacement groove 5 into the interior of the pipette cartridge 1 through the replacement inlet 52 .

[0047] In this embodiment, the lower end of the screw rod 363 is fixedly connected to an electric suction cup 37. The electric suction cup 37 is a prior art and is used by powering on. A suction head 38 is provided on the electric suction cup 37, and a connecting frame No. 1 39 is fixedly connected to the outer shell of the electric suction cup 37. The lower end of the connecting frame No. 1 39 is fixedly connected to a T-shaped limit block 310.

[0048] Specifically, during the replacement process of the used wiping component 4, the electric suction cup 37 is first turned off so that the suction head 38 no longer has an adsorption force on the wiping component 4. After the new wiping component 4 pushes the used wiping component 4 inside the pipette tube 1 out from the replacement outlet 12 along the T-shaped limit block 310, the new wiping component 4 slides onto the T-shaped limit block 310 again, and the electric suction cup 37 is started again to make the suction head 38 adsorb the new wiping component 4.

[0049] In this embodiment, a wiping assembly 4 is disposed below the suction head 38 , a guide groove 42 is disposed on the wiping assembly 4 , a slide groove 41 is disposed on the upper surface of the wiping assembly 4 , and the slide groove 41 is slidably disposed with the T-shaped limit block 310 .

[0050] The above embodiments are only used to illustrate the technical method of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical method of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical method of the present invention.

Claims

1. A liquid transfer structure for a chemiluminescence measuring instrument, comprising a liquid transfer cartridge (1), characterized in that: It also includes a cleaning mechanism (3) which is arranged on the pipette tube (1) through the connecting seat (2) and is used to clean the waste liquid after pipetting inside the pipette tube (1); The cleaning mechanism (3) comprises a reagent box (31) for storing a cleaning liquid, a connecting pipe (32) being arranged on the reagent box (31), a delivery pump (33) being arranged between the reagent box (31) and the connecting pipe (32), a reciprocating assembly and a driving assembly for driving the reciprocating assembly to move and a resetting assembly capable of resetting the reciprocating assembly being installed on the delivery pump (33), and a wiping assembly (4) for wiping the inner wall of the pipette tube (1) being installed on the reciprocating assembly; The replacement mechanism is arranged on the pipette cartridge (1) and is used to replace the wiping component (4) inside the pipette cartridge (1) after use.

2. The liquid transfer replacement structure for a chemiluminescence measuring instrument according to claim 1, characterized in that: The reciprocating assembly comprises a first connecting rod (36), the first connecting rod (36) is rotatably connected to a second connecting rod (361), the second connecting rod (361) is rotatably connected to a connecting block (362), and the lower end of the connecting block (362) is rotatably connected to a screw rod (363).

3. The liquid transfer replacement structure for a chemiluminescence measuring instrument according to claim 2, characterized in that: The driving assembly comprises a transmission shaft (351), and the interior of the connecting pipe (32) is fixedly connected to a first fixing frame (34), and the transmission shaft (351) is rotatably connected to the first fixing frame (34), one end of the transmission shaft (351) is fixedly connected to a water wheel blade (35), and the other end of the transmission shaft (351) is fixedly connected to a first bevel gear (352), the first bevel gear (352) is meshed with a second bevel gear (353), and the interior of the second bevel gear (353) is fixedly connected to a rotating shaft (354), the rotating shaft (354) is rotatably connected to the connecting pipe (32), and the rotating shaft (354) is fixedly connected to a first connecting rod (36).

4. The liquid transfer replacement structure for a chemiluminescence measuring instrument according to claim 2, characterized in that: The lower end of the screw rod (363) is fixedly connected to an electric suction cup (37), a suction head (38) is provided on the electric suction cup (37), and a first connecting frame (39) is fixedly connected to the outer shell of the electric suction cup (37), and a T-shaped limit block (310) is fixedly connected to the lower end of the first connecting frame (39).

5. The liquid transfer replacement structure for a chemiluminescence measuring instrument according to claim 4, characterized in that: A wiping assembly (4) is arranged below the suction head (38), and a symmetrically arranged guide groove (42) is arranged on the wiping assembly (4). A sliding groove (41) is arranged on the upper surface of the wiping assembly (4), and the sliding groove (41) and the T-shaped limit block (310) are slidably arranged.

6. The liquid transfer replacement structure for a chemiluminescence measuring instrument according to claim 2, characterized in that: The reset component comprises a second fixing frame (311) fixedly connected to the connecting seat (2), two sliding shafts (3111) fixedly connected to the second fixing frame (311), an iron block (3114) slidably connected to the sliding shaft (3111), and a reset spring (3112) is sleeved on the outer side of the sliding shaft (3111), the reset spring (3112) is arranged between the connecting seat (2) and the iron block (3114), an electromagnet (3113) is arranged on the second fixing frame (311), and the electromagnet (3113) is magnetically connected to the iron block (3114), and the iron block (3114) is fixedly connected to the connecting block (362).

7. The liquid transfer replacement structure for a chemiluminescence measuring instrument according to claim 2, characterized in that: A second connecting frame (314) is fixedly connected to the connecting seat (2), a threaded sleeve (315) is fixedly connected to the second connecting frame (314), and the threaded sleeve (315) is threadedly connected to the screw rod (363).

8. The liquid transfer and replacement structure for a chemiluminescence measuring instrument according to claim 5, characterized in that: The replacement mechanism comprises a replacement groove (5) fixedly connected to the pipette cylinder (1); a guide rod (51) is provided on the replacement groove (5), and the guide rod (51) is slidably connected to the guide groove (42) on the wiping assembly (4); a replacement inlet (52) for delivering the wiping assembly (4) into the pipette cylinder (1) is provided on the replacement groove (5); a No. 3 fixing frame (53) is fixedly connected to the replacement groove (55); a cylinder (54) is fixedly connected to the No. 3 fixing frame (53); a push block (55) is fixedly connected to the output end of the cylinder (54); and the push block (55) is slidably connected to the slide groove (41) on the wiping assembly (4).

9. The liquid transfer and replacement structure for a chemiluminescence measuring instrument according to claim 1, characterized in that: The pipette cylinder (1) is provided with a liquid inlet tube (11) extending therethrough, and the pipette cylinder (1) is provided with a replacement outlet (12).

10. The liquid transfer and replacement structure for a chemiluminescence measuring instrument according to claim 6, characterized in that: The second fixing frame (311) is provided with a sensor (312), and the connecting seat (2) is provided with a controller (313).

Images