A purification device and purification method for nicotinamide riboside

Abstract

The present invention relates to the technical field of purification of nicotinamide riboside, and specifically to a purification device and a purification method for nicotinamide riboside, comprising a purification component, a filtering component is fixedly installed at the lower end of the purification component, an adjusting component is fixedly installed on the purification component, the purification component comprises a purification barrel, a nicotinamide riboside feed port is fixedly installed on the purification barrel, a methanol feed port is fixedly installed on the upper end of the purification barrel, a motor is fixedly installed on the upper end of the purification barrel, a stirring rod is fixedly installed at the output end of the motor, and a stirring blade is fixedly installed on the stirring rod. The purpose of the present invention is to cool and crystallize nicotinamide riboside through the purification component, and then drive a piston block through the adjusting component alone by pushing and pulling a piston rod, adjust the size of a feed port, change the cold air transmission rate, make the purification reaction more sufficient, and then filter the nicotinamide riboside crystals through the filter component.

Description

Technical Field

[0001] The present invention relates to the technical field of nicotinamide riboside purification, and specifically to a nicotinamide riboside purification device and a nicotinamide riboside purification method. Background Art

[0002] Nicotinamide riboside is a compound with multiple biological activities. It is a derivative of vitamin B3 and a precursor of nicotinamide adenine dinucleotide (NAD+, also known as coenzyme I). The solubility of nicotinamide riboside in methanol usually decreases with decreasing temperature. When the solution is cooled to a certain temperature, the solubility will drop below a critical value, at which point nicotinamide riboside will precipitate from the solution to form crystals.

[0003] At present, when nicotinamide riboside is purified, cold air circulation is usually used to cool the solution to crystallize nicotinamide riboside. During the purification process, if the temperature does not reach the critical value, the cold air transmission rate remains unchanged, and the temperature control of the cold air circulation is inaccurate, it may cause the crystallization rate of nicotinamide riboside to be too slow or incomplete, thereby affecting the purification efficiency. Summary of the invention

[0004] The object of the present invention is to provide a purification device and a purification method for nicotinamide riboside, wherein nicotinamide riboside is cooled and crystallized by a purification component, and then a piston block is driven by a regulating component by pushing and pulling a piston rod, and the size of the opening of a piston pipe is adjusted to change the cold air transmission rate, so that the purification reaction is more sufficient, and then the nicotinamide riboside crystals are filtered through a filter component.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: a purification method for a nicotinamide riboside purification device, comprising a purification component, a filtering component is fixedly installed at the lower end of the purification component, an adjusting component is fixedly installed on the purification component, the purification component comprises a purification barrel, a nicotinamide riboose feed port is fixedly installed on the purification barrel, a methanol feed port is fixedly installed on the upper end of the purification barrel, a motor is fixedly installed on the upper end of the purification barrel, a stirring rod is fixedly installed on the output end of the motor, a stirring blade is fixedly installed on the stirring rod, a condenser is fixedly installed on the outer surface of the purification component, a thermometer is fixedly installed inside the purification component, the filtering component comprises a protective barrel, the A filter box is installed inside the protective barrel, a drainage pipe is fixedly installed inside the filter box, a switch door is fixedly installed on the filter box, the adjustment component includes a push-pull rod, a piston rod 1 is installed on one side of the push-pull rod, a piston block 1 is fixedly installed on one side of the piston rod, a piston pipe 1 is installed on the outer surface of the piston block 1, a discharge port 1 is provided at a lower end of the piston pipe, and a discharge port 4 is provided at an upper end of the piston pipe, a piston rod 2 is fixedly installed on the other side of the push-pull rod, a piston block 2 is fixedly installed on one side of the piston rod 2, a piston pipe 2 is installed on the outer surface of the piston block 2, a discharge port 2 is provided at the upper end of the piston pipe 2, and a discharge port 3 is provided at the lower end of the piston pipe 2.

[0006] Preferably, a protective shell is fixedly installed on the outer surface of the condenser, an air inlet is provided on one side of the condenser, and an air outlet is also provided on the other side of the condenser.

[0007] Preferably, one side of the air inlet extends through the protective shell installation, and one side of the air outlet extends through the protective shell installation.

[0008] Preferably, slide grooves are provided on both sides of the protection barrel, and sliding blocks are slidably connected to both sides of the upper end of the filter box, and the filter box is located inside the protection barrel, and the filter box is slidably connected to the protection barrel.

[0009] Preferably, a second handle is fixedly mounted on one side of the filter box, and a second handle is fixedly mounted on the switch door.

[0010] Preferably, one side of the piston rod extends through the push-pull rod for installation, and a nut is rotatably connected to the push-pull rod, and one side of the nut passes through the piston rod and the push-pull rod.

[0011] Preferably, the feed port 1 is connected to the air inlet of the condenser, and the feed port 1 and the air inlet are externally connected to a cold air transmission device.

[0012] Preferably, a feed discharge port is provided at the lower end of the purification barrel, and a feed feed port is provided at the lower end of the protection barrel.

[0013] Preferably, the second feed port is connected to the feed port at the lower end of the purification barrel, and the third feed port is connected to the feed port at the lower end of the protection barrel.

[0014] A method for purifying nicotinamide riboside comprises the following steps:

[0015] Step 1: Workers pour nicotinamide riboside and methanol into the purification barrel through the nicotinamide riboside feed port and the methanol feed port respectively, and start the motor at the same time. The stirring blade slowly stirs to dissolve the nicotinamide riboside in the methanol, and then transports cold air into the condenser to cool the mixed solution of nicotinamide riboside and methanol inside the purification barrel. At the same time, the stirring blade slowly stirs to make the mixed solution more evenly and fully cooled;

[0016] Step 2: The worker judges the temperature based on the thermometer inside the purification barrel. If the temperature is too high or too low, the worker pushes and pulls the push-pull rod to drive the piston rod 1 and the piston rod 2 on one side to move, thereby driving the piston block 1 and the piston block 2 to move. The piston block 1 opens the discharge port 1, and the cold air is connected. At the same time, the piston block 2 closes the discharge port 2 to prevent the mixed liquid from falling during the cold air crystallization process. The worker rotates the nut to separate the nut from the piston rod 1. The worker can push and pull the piston rod 1 to drive the piston block 1 alone to adjust the size of the discharge port 1, change the cold air transmission rate, and make the purification reaction more sufficient.

[0017] Step 3: When the reaction of the mixed solution is completed, nicotinamide riboside cools and crystallizes. By pulling the push-pull rod, the first discharge port is closed and the third discharge port is opened. The mixed solution and the nicotinamide riboside crystals fall into the filter box together. The mixed solution is filtered out through the filter box, and the drainage pipe discharges the mixed solution. Then the worker opens the switch door through the first handle, and then pulls the second handle to slide through the slide groove and the slider to pull out the filter box and take out the purified nicotinamide riboside crystals.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] 1. The worker pours nicotinamide riboside and methanol into the purification barrel through the nicotinamide riboside feed port and the methanol feed port respectively, and starts the motor at the same time. The stirring blade slowly stirs along with the stirring rod to dissolve the nicotinamide riboside in the methanol, and then transports cold air into the condenser to cool the mixed solution of nicotinamide riboside and methanol in the purification barrel. At the same time, the stirring blade slowly stirs the mixed solution so that the mixed solution is cooled more evenly and fully;

[0020] 2. The worker judges the temperature based on the thermometer inside the purification barrel. If the temperature is too high or too low, the worker rotates the nut to separate the nut from the piston rod. The worker can push and pull the piston rod to drive the piston block to adjust the size of the discharge port, change the cold air transmission rate, and change the temperature.

[0021] 3. When the reaction of the mixed solution is completed, the nicotinamide riboside cools and crystallizes, and the mixed solution and the nicotinamide riboside crystals fall into the filter box together. The mixed solution is filtered out through the filter box, and the drainage pipe discharges the mixed solution. Then the worker pulls out the filter box and takes out the purified nicotinamide riboside crystals. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0023] Figure 2 It is a schematic diagram of the overall rear view structure of the present invention;

[0024] Figure 3 It is a schematic diagram of the overall structure analysis of the present invention;

[0025] Figure 4 It is a schematic diagram of the structure of the purification component of the present invention;

[0026] Figure 5 It is a schematic diagram of the structure of the stirring assembly of the present invention;

[0027] Figure 6 It is a schematic diagram of the structure of the filter assembly of the present invention;

[0028] Figure 7 It is a schematic diagram of the structure of the regulating component of the present invention.

[0029] In the figure: 1. Purification component; 101. Purification barrel; 102. Nicotinamide riboside feed port; 103. Methanol feed port; 104. Motor; 105. Stirring rod; 106. Stirring blade; 107. Condenser; 108. Thermometer; 109. Protective shell; 2. Filter component; 201. Protective barrel; 202. Filter box; 203. Second handle; 204. Drain pipe; 205. Switch door; 206. First handle; 3. Adjustment component; 301. Push-pull rod; 302. Piston rod one; 303. Nut; 304. Piston block one; 305. Piston pipe one; 306. Feed port one; 307. Feed port four; 308. Piston rod two; 309. Piston block two; 311. Piston pipe two; 312. Feed port two; 313. Feed port three. DETAILED DESCRIPTION

[0030] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0031] The present invention provides a purification device and a purification method for nicotinamide riboside, comprising a purification component 1, a filtering component 2 having a filtering function for filtering nicotinamide riboside crystals is fixedly installed at the lower end of the purification component 1, and a regulating component 3 having a cooling air rate regulating function is fixedly installed on the purification component 1;

[0032] See also Figures 1 to 5 As shown, the purification component 1 includes a purification barrel 101, which provides a place for chemical reaction of nicotinamide ribose and methanol. A nicotinamide ribose feed port 102 is fixedly installed on the purification barrel 101, and the nicotinamide ribose feed port 102 is convenient for workers to pour nicotinamide ribose for purification. A methanol feed port 103 is fixedly installed on the upper end of the purification barrel 101, and the methanol feed port 103 is convenient for workers to pour methanol and nicotinamide ribose to react. A motor 104 is fixedly installed on the upper end of the purification barrel 101. The worker starts the motor to start working. A stirring rod 105 is fixedly installed on the output end of the motor 104, and the motor 104 drives the stirring rod 105 The stirring rod 105 is rotated, and a stirring blade 106 is fixedly installed on the stirring rod 105. The stirring rod 105 drives the stirring blade 106 to stir slowly to dissolve nicotinamide riboside in methanol. A condenser 107 is fixedly installed on the outer surface of the purification component 1. Cold air is transported into the condenser 107 to cool the mixed solution of nicotinamide riboside and methanol in the purification barrel 101. At the same time, the stirring blade 106 stirs slowly to make the mixed solution more uniform and fully cooled. A thermometer 108 is fixedly installed inside the purification component 1. Workers judge the temperature based on the thermometer 108 inside the purification barrel 101.

[0033] See also Figures 1 to 6 As shown, the filtering assembly 2 includes a protective barrel 201, which prevents the mixed liquid from splashing during filtration. A filtering box 202 is installed inside the protective barrel 201, and the filtering box 202 filters the purified nicotinamide riboside crystals. A drainage pipe 204 is fixedly installed inside the filtering box 202 to discharge the filtered mixed liquid. A switch door 205 is fixedly installed on the filtering box 202 to facilitate workers to take materials.

[0034] See also Figure 7As shown, the adjustment component 3 includes a push-pull rod 301, which is convenient for workers to adjust and drive other devices to operate. A piston rod 302 is installed on one side of the push-pull rod 301, and the piston rod 302 moves with the push-pull rod 301, or moves independently. A piston block 304 is fixedly installed on one side of the piston rod 302, and the piston block 304 moves with the piston rod 302 to adjust the cooling air rate. A piston pipe 305 is installed on the outer surface of the piston block 304, and the piston pipe 305 provides a movement place for the piston block. A discharge port 306 is arranged at the lower end of the piston pipe 305, and the discharge port 306 is used to transmit cold air. A discharge port 4 307 is provided at the upper end of the piston pipe 1 305 for connecting and transmitting cold air. A piston rod 2 308 is fixedly installed on the other side of the push-pull rod 301, and the piston rod 2 308 moves with the push-pull rod 301. A piston block 2 309 is fixedly installed on one side of the piston rod 2 308, and the piston block 2 309 moves with the piston rod 2 308 to open and close the opening of the filter component 2. A piston pipe 2 311 is installed on the outer surface of the piston block 2 to provide a movement place for the piston block 2. A discharge port 2 312 is provided at the upper end of the piston pipe 2 311 for discharge, and a discharge port 3 313 is provided at the lower end of the piston pipe 2 311 for discharge.

[0035] In an optional embodiment, a protective shell 109 is fixedly installed on the outer surface of the condenser 107, and the protective shell 109 protects the internal device. An air inlet is provided on one side of the condenser 107 for connecting and transmitting cold air, and an air outlet is also provided on the other side of the condenser 107 for discharging the circulating cold air.

[0036] In an optional embodiment, one side of the air inlet extends through the protective shell 109 for installation, and one side of the air outlet extends through the protective shell 109 for installation.

[0037] In an optional embodiment, slide grooves are opened on both sides of the protective barrel 201 to provide a sliding place. Slide blocks are slidably connected on both sides of the upper end of the filter box 202 to assist the sliding of the filter box 202. The filter box 202 is located inside the protective barrel 201, and the filter box 202 is slidably connected to the protective barrel 201.

[0038] In an optional embodiment, a second handle 203 is fixedly installed on one side of the filter box 202, and a second handle 203 is fixedly installed on the switch door 205. The second handle 203 facilitates workers to take out the purified nicotinamide riboside crystals.

[0039] In an optional embodiment, one side of the piston rod 302 extends through the push-pull rod 301 for installation, and a nut 303 is rotatably connected to the push-pull rod 301. One side of the nut 303 passes through the piston rod 302 and the push-pull rod 301. The worker judges the temperature based on the thermometer 108 inside the purification barrel 101. When the temperature is too high or too low, the worker rotates the nut 303 to separate the nut 303 from the piston rod 302. The piston block 304 can be driven by pushing and pulling the piston rod 302 alone to adjust the size of the discharge port 306, change the cold air transmission rate, and change the temperature.

[0040] In an optional embodiment, the feed port 306 is connected to the air inlet of the condenser 107, and the air inlet of the feed port 306 is externally connected to a cold air transmission device, which transmits cold air through a piston pipe 305, and then adjusts the cold air transmission rate through a piston block 304.

[0041] In an optional embodiment, a discharge port is provided at the lower end of the purification barrel 101 for circulating and transferring the mixed liquid, and a feed port is provided at the lower end of the protection barrel 201 for circulating and transferring the mixed liquid.

[0042] In an optional embodiment, the second feed port 312 is connected to the feed port at the lower end of the purification barrel 101 for circulating and transferring the mixed liquid, and the third feed port 313 is connected to the feed port at the lower end of the protection barrel 201 for circulating and transferring the mixed liquid.

[0043] A method for purifying nicotinamide riboside comprises the following steps:

[0044] Step 1: The worker pours nicotinamide riboside and methanol into the purification barrel 101 through the nicotinamide riboside feed port 102 and the methanol feed port 103, respectively, and starts the motor 104 at the same time, and the stirring blade 106 slowly stirs to dissolve the nicotinamide riboside in the methanol, and then delivers cold air through the condenser 107 to cool the nicotinamide riboside and methanol mixed solution inside the purification barrel 101, and at the same time, slowly stirs through the stirring blade 106 to make the mixed solution more uniform and fully cooled;

[0045] Step 2: The worker judges the temperature according to the thermometer 108 inside the purification barrel 101. If the temperature is too high or too low, the worker pushes and pulls the push-pull rod 301 to drive the piston rod 1 302 and the piston rod 2 308 on one side to move, thereby driving the piston block 1 304 and the piston block 2 309 to move. The piston block 1 304 opens the discharge port 1 306, and the cold air is connected. At the same time, the piston block 2 309 closes the discharge port 2 312 to prevent the mixed liquid from falling during the cold air crystallization process. The worker rotates the nut 303 to separate the nut 303 from the piston rod 1 302. The worker can drive the piston block 1 304 by pushing and pulling the piston rod 1 302 alone to adjust the size of the discharge port 1 306, change the cold air transmission rate, and make the purification reaction more sufficient.

[0046] Step 3: When the reaction of the mixed solution is completed, the nicotinamide riboside is cooled and crystallized, and by pulling the push-pull rod 301, the discharge port 1 306 is closed, and the discharge port 3 313 is opened, and the mixed solution and the nicotinamide riboside crystals fall into the filter box 202 together, and the mixed solution is filtered out through the filter box 202, and the drainage pipe 204 discharges the mixed solution. Then the worker opens the switch door 205 through the first handle 206, and then pulls the second handle 203 to slide through the slide groove and the slider, pulls out the filter box 202, and takes out the purified nicotinamide riboside crystals.

[0047] Working principle: workers pour nicotinamide riboside and methanol into the purification barrel 101 through the nicotinamide riboside feed port 102 and the methanol feed port 103 respectively, and start the motor 104 at the same time. The motor 104 drives the stirring rod 105 to rotate, and the stirring blade 106 follows the stirring rod 105 to slowly stir, so that the nicotinamide riboside is dissolved in the methanol, and then the cold air is transported into the condenser 107 to cool the nicotinamide riboside and methanol mixed solution inside the purification barrel 101. At the same time, the stirring blade 106 stirs slowly to make the mixed solution more uniform and fully cooled. The worker judges the temperature according to the thermometer 108 inside the purification barrel 101. If the temperature is too high or too low, the push-pull rod 301 is pushed to drive the piston rod 1 302 and the piston rod 2 308 on one side to move, thereby driving the piston block 1 304 and the piston block 2 309 to move, and the piston block 1 304 opens the discharge port 1 306 , the cold air is turned on, and at the same time, the piston block 309 closes the discharge port 312 to prevent the mixed solution from falling during the cold air crystallization process. The worker rotates the nut 303 to separate the nut 303 from the piston rod 302, and can drive the piston block 304 by pushing and pulling the piston rod 302 alone to adjust the size of the discharge port 306, change the cold air transmission rate, and make the purification reaction more sufficient. When the mixed solution reacts, the nicotinamide riboside cools and crystallizes, by pulling the push-pull rod 301, the discharge port 306 is closed, and the discharge port 313 is opened, and the mixed solution and the nicotinamide riboside crystals fall into the filter box 202 together. The mixed solution is filtered out through the filter box 202, and the drainage pipe 204 discharges the mixed solution. Then the worker opens the switch door 205 through the first handle 206, and then pulls the second handle 203 to slide through the slide groove and the slider, pulls out the filter box 202, and takes out the purified nicotinamide riboside crystals.

[0048] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A purification device for nicotinamide riboside, comprising a purification component (1), characterized in that: A filtering component (2) is fixedly mounted on the lower end of the purification component (1), and an adjusting component (3) is fixedly mounted on the purification component (1); The purification component (1) comprises a purification barrel (101), a nicotinamide ribose feed port (102) is fixedly mounted on the purification barrel (101), a methanol feed port (103) is fixedly mounted on the upper end of the purification barrel (101), a motor (104) is fixedly mounted on the upper end of the purification barrel (101), a stirring rod (105) is fixedly mounted on the output end of the motor (104), a stirring blade (106) is fixedly mounted on the stirring rod (105), a condenser (107) is fixedly mounted on the outer surface of the purification component (1), and a thermometer (108) is fixedly mounted inside the purification component (1); The filter assembly (2) comprises a protective barrel (201), a filter box (202) is installed inside the protective barrel (201), a liquid discharge pipe (204) is fixedly installed inside the filter box (202), and a switch door (205) is fixedly installed on the filter box (202); The adjusting assembly (3) comprises a push-pull rod (301), a piston rod 1 (302) is installed on one side of the push-pull rod (301), a piston block 1 (304) is fixedly installed on one side of the piston rod 1 (302), a piston pipe 1 (305) is installed on the outer surface of the piston block 1 (304), a discharge port 1 (306) is provided at the lower end of the piston pipe 1 (305), a discharge port 4 (307) is provided at the upper end of the piston pipe 1 (305), a piston rod 2 (308) is fixedly installed on the other side of the push-pull rod (301), and A piston block 2 (309) is fixedly installed on one side of the piston rod 2 (308), a piston pipe 2 (311) is installed on the outer surface of the piston block 2 (309), a discharge port 2 is arranged at the upper end of the piston pipe 2 (311), and a discharge port 3 (313) is arranged at the lower end of the piston pipe 2 (311), one side of the piston rod 1 (302) extends through the push-pull rod (301) for installation, a nut (303) is rotatably connected to the push-pull rod (301), and one side of the nut (303) passes through the piston rod 1 (302) and the push-pull rod (301).

2. A purification device for nicotinamide riboside according to claim 1, characterized in that: A protective shell (109) is fixedly mounted on the outer surface of the condenser tube (107); an air inlet is provided on one side of the condenser tube (107); and an air outlet is also provided on the other side of the condenser tube (107).

3. A purification device for nicotinamide riboside according to claim 2, characterized in that: One side of the air inlet extends through the protective shell (109) for installation, and one side of the air outlet extends through the protective shell (109) for installation.

4. A purification device for nicotinamide riboside according to claim 3, characterized in that: Slide grooves are provided on both sides of the protection barrel (201), and sliding blocks are slidably connected to both sides of the upper end of the filter box (202). The filter box (202) is located inside the protection barrel (201), and the filter box (202) is slidably connected to the protection barrel (201).

5. The device for purifying nicotinamide riboside according to claim 4, characterized in that: A second handle (203) is fixedly mounted on one side of the filter box (202), and a second handle (203) is fixedly mounted on the switch door (205).

6. The device for purifying nicotinamide riboside according to claim 5, characterized in that: The feed inlet 1 (306) is connected to the air inlet of the condenser (107), and the air inlet of the feed inlet 1 (306) is externally connected to a cold air transmission device.

7. The device for purifying nicotinamide riboside according to claim 6, characterized in that: A material discharge port is provided at the lower end of the purification barrel (101), and a material feed port is provided at the lower end of the protection barrel (201).

8. The device for purifying nicotinamide riboside according to claim 7, characterized in that: The second feed opening (312) is connected to the feed opening at the lower end of the purification barrel (101), and the third feed opening (313) is connected to the feed opening at the lower end of the protection barrel (201).

9. A method for purifying nicotinamide riboside, using the nicotinamide riboside purification device of claim 8, characterized in that: The method comprises the following steps: Step 1: A worker pours nicotinamide riboside and methanol into the purification barrel (101) through the nicotinamide riboside feed port (102) and the methanol feed port (103), respectively, and starts the motor (104) at the same time. The stirring blade (106) slowly stirs to dissolve the nicotinamide riboside in the methanol, and then cold air is transported into the purification barrel (101) through the condenser (107) to cool the nicotinamide riboside and methanol mixed solution inside the purification barrel (101). At the same time, the stirring blade (106) slowly stirs to make the mixed solution more uniform and fully cooled; Step 2: The worker judges the temperature based on the thermometer (108) inside the purification barrel (101). If the temperature is too high or too low, the worker pushes and pulls the push-pull rod (301) to drive the piston rod 1 (302) and the piston rod 2 (308) on one side to move, thereby driving the piston block 1 (304) and the piston block 2 (309) to move. The piston block 1 (304) opens the discharge port 1 (306) to connect the cold air. At the same time, the piston block 2 (309) closes the discharge port 2 (312) to prevent the mixed liquid from falling during the cold air crystallization process. The worker rotates the nut (303) to separate the nut (303) from the piston rod 1 (302). The worker can drive the piston block 1 (304) by pushing and pulling the piston rod 1 (302) alone to adjust the size of the discharge port 1 (306) and change the cold air transmission rate to make the purification reaction more complete. Step 3: When the reaction of the mixed solution is completed, the nicotinamide riboside is cooled and crystallized. By pulling the push-pull rod (301), the discharge port 1 (306) is closed and the discharge port 3 (313) is opened. The mixed solution and the nicotinamide riboside crystals fall together into the filter box (202). The mixed solution is filtered out through the filter box (202), and the discharge pipe (204) discharges the mixed solution. The switch door (205) is opened, and then the second handle (203) is pulled to slide through the slide groove and the slider to pull out the filter box (202) and take out the purified nicotinamide riboside crystals.

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