Plasma separation device

Abstract

The application discloses a plasma separation device, which comprises a shell, a cavity arranged in the shell, an opening arranged on the cavity, a sealing mechanism hinged at the opening, a support platform arranged in the cavity, a plurality of slidingly connected limiting pieces arranged on the support platform, a magnetic attraction fixing piece arranged in the cavity, one end of the magnetic attraction fixing piece being insertedly fixed with the sealing mechanism, the magnetic attraction fixing piece facing the plurality of limiting pieces respectively, a plurality of color sensors fixed on the bottoms of the corresponding limiting pieces respectively, a plurality of pushing components arranged on the support platform and arranged in one-to-one correspondence with the plurality of limiting pieces respectively, the driving end of the pushing component being detachably connected with the corresponding limiting piece, and a driving mechanism arranged in the cavity. Therefore, the separation time of different plasma can be reasonably controlled, the separation effect of the plasma is improved, and unnecessary sample loss is avoided.

Description

Technical Field

[0001] This invention relates to the field of medical technology, and in particular to a plasma separation device. Background Technology

[0002] Currently, centrifuges are commonly used to process multiple containers of plasma simultaneously, enabling the separation of multiple plasma samples in a single centrifugation. However, maintaining specific temperature and humidity conditions is crucial during plasma storage and transportation. Different storage environments directly affect the stability and activity of the various components in the plasma, leading to variations in the required centrifugation time. Therefore, due to the differing stability and activity of individual plasma samples, the optimal separation time also varies.

[0003] The existing method of using a uniform separation time for multiple plasma samples is insufficient to achieve ideal separation results. If the time is too short, serum and blood cells may not be completely separated; if the time is too long, not only will the separation quality not be further improved, but unnecessary sample loss may also occur. Summary of the Invention

[0004] The present invention aims to at least partially solve one of the technical problems in the related art.

[0005] Therefore, one objective of this invention is to provide a plasma separation device that can reasonably control the separation time of different plasmas, thereby improving the plasma separation effect and avoiding unnecessary sample loss.

[0006] To achieve the above objectives, the present invention proposes a plasma separation device, comprising: a shell, wherein a cavity is provided inside the shell and an opening is provided on the cavity, and a sealing mechanism is hinged to the opening; a support platform, disposed in the cavity, wherein multiple slidingly connected limiting members are provided on the support platform for limiting and fixing plasma tubes; a magnetic suction fixing member, disposed in the cavity, one end of the magnetic suction fixing member being inserted and fixed to the sealing mechanism, the magnetic suction fixing member facing the multiple limiting members respectively, for adsorbing and detaching plasma tubes within a preset distance from the limiting members; and multiple color sensors, respectively fixed on the bottom of the corresponding limiting members, for acquiring... The system includes: separation data and position of the upper plasma tube; multiple pushing components, each disposed on the support platform and corresponding to multiple limiting components, with the driving end of each pushing component detachably connected to the corresponding limiting component for driving the limiting component to move; a driving mechanism disposed in the cavity and fixed to the support platform by a magnetic fastener, for driving the support platform to rotate; and a controller disposed on the housing and connected to the color sensor, pushing components, and driving mechanism for controlling the pushing components and driving mechanism based on the received separation data.

[0007] The plasma separation device of this invention activates a drive mechanism, which drives a support platform to rotate, causing the plasma tubes to separate plasma due to centrifugal force. During the separation process, a color sensor continuously monitors the separation degree of the corresponding plasma tubes above and sends the generated separation data to a controller. When the controller determines that the separation color of the plasma tube reaches a preset standard, it controls the drive mechanism to stop operating and records the angle position after the drive mechanism stops rotating to prevent subsequent tubes from colliding due to the same angle after rotation stops. Simultaneously, the controller controls the pushing component to drive the limiting component to move towards the magnetic fixing component by a preset distance. When the distance between the limiting component and the magnetic fixing component shortens to a certain range, the plasma tube is attracted to the magnetic fixing component. Furthermore, if the color sensor does not detect a color change during the separation process, it sends data to the controller. The controller determines based on this data that the tube has detached from the support and controls the drive mechanism to continue operating. The above steps are repeated to achieve the separation of multiple plasma tubes. This allows for reasonable control of the separation time of different plasmas, thereby improving the plasma separation effect and avoiding unnecessary sample loss.

[0008] In addition, the plasma separation device proposed in the application may also have the following additional technical features:

[0009] Specifically, the limiting component includes a clamp, a bracket, a sleeve, and an adsorption component. The supporting platform has multiple through slots arranged at equal angles, and the inner wall of each through slot has two sliding grooves. The two ends of the clamp are fixedly connected to sliders in their respective sliding grooves. The bracket is L-shaped and fixedly connected to the clamp, and the bracket is detachably connected to the driving end of the pushing component. The sleeve is fitted into the clamp, and one end of the sleeve is attached to the bracket; the sleeve is used to accommodate the plasma tube. The adsorption component is disposed on the sleeve, and the adsorption component is adsorbed and connected to the magnetic fixing component.

[0010] Specifically, the through groove gradually widens from the direction of the pushing component toward the magnetic fastener, and the opening of the clamp faces toward the magnetic fastener.

[0011] Specifically, the drive mechanism includes a motor, a mounting bracket, and multiple shock-absorbing legs, wherein the motor is mounted on the mounting bracket; one end of each of the multiple shock-absorbing legs is respectively mounted on the bottom wall of the cavity, and the other end of each of the multiple shock-absorbing legs is respectively fixedly connected to the mounting bracket.

[0012] Specifically, the support platform includes a collar, multiple support rods, and a support platform. The collar is sleeved on the output shaft of the motor. One end of each support rod is fixed to the collar, and the other end is fixed to the support platform. A central hollow area is formed on the support platform, and multiple through slots are arranged around the central hollow area.

[0013] Specifically, the magnetic fastener includes a threaded fastener, a one-way bearing, and a magnetic element. One end of the threaded fastener is threaded into a threaded hole on the motor output shaft, and the other end of the threaded fastener abuts against the collar to fix the collar to the motor output shaft. The one-way bearing is fixed to the threaded fastener. The magnetic element passes through the central hollow area of ​​the support platform, with one end of the magnetic element's shaft connected to the one-way bearing, and the other end of the magnetic element being engaged in the sealing mechanism.

[0014] Specifically, it also includes an inner liner and a second sealing ring. The inner liner has a folded edge, which is engaged at the opening, and the inner liner extends into the cavity. The support platform and the magnetic fastener are both disposed in the inner liner. The bottom of the inner liner has a through hole, the second sealing ring is installed at the through hole, and the second sealing ring is sleeved on the upper end cover of the motor.

[0015] Specifically, a circular second groove is provided on the outer wall of the upper end cover of the motor, and the end of the second sealing ring away from the inner liner is fitted in the second groove, and the second groove is higher than the bottom wall of the inner liner; the end of the collar near the upper end cover of the motor covers the upper end cover and the second sealing ring, and there is a gap between the collar and the upper end cover of the motor.

[0016] Specifically, the sealing mechanism includes an upper cover, a sealing plate, and a first sealing ring, wherein the upper cover is hinged to the opening, the first sealing ring is fixed on the folded edge, and the first sealing ring is in contact with the upper cover;

[0017] The first sealing ring has a first groove, and the sealing plate is snapped and fitted between the first groove and the upper cover.

[0018] Specifically, the sealing plate has a spline groove at one end near the magnetic fastener, and the magnetic fastener has a spline rod at one end near the spline groove, with the spline rod inserted into the spline groove. Attached Figure Description

[0019] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with the invention and, together with the description, serve to explain the principles of the invention.

[0020] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0021] Figure 1 A cross-sectional view of a plasma separation apparatus according to an embodiment of the present invention;

[0022] Figure 2 This is a schematic diagram of a plasma separation device according to an embodiment of the present invention;

[0023] Figure 3 This is a partial structural schematic diagram of a plasma separation device according to an embodiment of the present invention;

[0024] Figure 4 This is a schematic diagram of the structure of a limiting member according to an embodiment of the present invention;

[0025] Figure 5 This is a partial structural schematic diagram of a plasma separation device according to another embodiment of the present invention;

[0026] Figure 6 According to an embodiment of the present invention Figure 1 Enlarged structural diagram of area A in the middle;

[0027] Figure 7 According to an embodiment of the present invention Figure 1 A magnified structural diagram of region B in the middle.

[0028] As shown in the figure:

[0029] 1. Housing; 10. Cavity; 11. Sealing mechanism; 110. Top cover; 111. Sealing plate; 112. First sealing ring; 1120. First groove; 2. Support platform; 20. Collar; 21. Support rod; 22. Support platform; 23. Limiting component; 220. Central hollow area; 221. Through groove; 2210. Slide groove; 230. Clamp; 231. Bracket; 232. Sleeve; 233. Adsorption component; 3. Magnetic fixing component; 30. Threaded fastener; 31. One-way bearing; 32. Magnetic component; 330. Spline rod; 4. Color sensor; 5. Pushing component; 6. Drive mechanism; 60. Motor; 61. Mounting bracket; 62. Shock-absorbing support leg; 600. Second groove; 7. Controller; 8. Liner; 80. Folded edge; 9. Second sealing ring. Detailed Implementation

[0030] To better understand the above-mentioned objectives, features, and advantages of the present invention, the solutions of the present invention will be further described below. It should be noted that, unless otherwise specified, the embodiments of the present invention and the features thereof can be combined with each other.

[0031] Many specific details are set forth in the following description in order to provide a full understanding of the invention, but the invention may also be practiced in other ways different from those described herein; obviously, the embodiments in the specification are only some embodiments of the invention, and not all embodiments.

[0032] The plasma separation apparatus of the present invention will now be described with reference to the accompanying drawings.

[0033] like Figure 1 , Figure 2 and Figure 3 As shown, the plasma separation device of this invention may include a housing 1, a support platform 2, a magnetic fixing component 3, a color sensor 4, a pushing component 5, a driving mechanism 6, and a controller 7.

[0034] Among them, refer to Figure 1 and Figure 2 The housing 1 has a cavity 10 inside, and the cavity 10 has an opening. A sealing mechanism 11 is hinged to the opening. The sealing mechanism 11 is used to seal the opening, which can maintain the cleanliness of the cavity 10. In addition, the tight closure of the sealing mechanism 11 can prevent blood from leaking out during the separation process, thereby avoiding pollution to the operator or the surrounding environment.

[0035] Furthermore, such as Figure 2 As shown, the sealing mechanism 11 includes an upper cover 110, a sealing plate 111, and a first sealing ring 112. The upper cover 110 is hinged at the opening, and the first sealing ring 112 is fixed on the folded edge 80. The first sealing ring 112 fits against the upper cover 110. This design ensures that the sealing mechanism 11 can form an effective sealing barrier when closed to prevent leakage of blood or other fluids.

[0036] The first sealing ring 112 has a first groove 1120. The sealing plate 111 snaps into place between the first groove 1120 and the upper cover 110. The snap-fit ​​between the first groove 1120 on the first sealing ring 112 and the sealing plate 111 further enhances the sealing effect. When the sealing plate 111 is snapped into place between the first groove 1120 and the upper cover 110, it forms an additional sealing layer, which helps prevent fluid leakage through tiny gaps.

[0037] As a possible alternative, observation holes can be provided at corresponding positions on the top cover 110 and the sealing plate 111. These holes allow for observation of the rotation within the plasma separator and also serve as ventilation and heat dissipation vents. Furthermore, the observation holes on the sealing plate 111 can also function as handles for easy and convenient removal, greatly improving operational convenience. The observation holes can also be fitted with sealing caps to prevent external impurities or air from entering the device. When observation or operation is required, the operator simply needs to open the sealing caps.

[0038] As another possibility, the sealing cap can be made of a transparent material, so that when it is necessary to observe the internal situation, there is no need to open the sealing cap, thus providing a more convenient way of observation.

[0039] The support platform 2 is set in the cavity 10, and the support platform 2 is provided with multiple slidingly connected limiting members 23 for limiting and fixing the plasma tube.

[0040] Furthermore, it can be referred to Figure 4 and Figure 5 The limiting component 23 includes a clamp 230, a bracket 231, a sleeve 232 and an adsorption component 233. The support platform 2 has multiple through slots 221 arranged at equal angles, and the inner wall of the through slots 221 has two sliding grooves 2210.

[0041] Both ends of the clamp 230 are fixedly connected to the sliders in the corresponding slide grooves 2210. The bracket 231 is L-shaped and fixedly connected to the clamp 230. The bracket 231 is detachably connected to the driving end of the pushing component 5. The sleeve 232 is clamped in the clamp 230, and one end of the sleeve 232 is attached to the bracket 231. The sleeve 232 is used to accommodate the plasma tube. The adsorption component 233 is set on the sleeve 232, and the adsorption component 233 can be adsorbed and connected to the magnetic fixing component 3.

[0042] It should be noted that the support 231, sleeve 232, and plasma tube are all made of transparent material. The use of transparent plastic allows the color sensor to easily detect the color inside the plasma tube through the support 231 and sleeve 232. Meanwhile, the clamp 230 is made of elastic material, such as a steel sheet, which can easily and firmly limit and fix the sleeve 232, ensuring its stability and reliability during operation. The sleeve 232 is adapted to the size of the plasma tube, thereby improving the stability of the plasma tube in the sleeve 232. The adsorption element 233 can be made of magnet or iron.

[0043] Specifically, when installing the plasma tube, simply insert the plasma tube into the sleeve 232 to secure it.

[0044] Furthermore, such as Figure 5 As shown, the opening of the through groove 221 gradually widens from the pushing component 5 toward the magnetic fixing component 3, while the opening of the clamp 230 faces the magnetic fixing component 3. This ingenious arrangement ensures that when the pushing component 5 pushes the sleeve 232 through the bracket 231, thereby moving the plasma tube toward the magnetic fixing component 3, the gradual expansion of the opening of the through groove 221 causes the movement of the slider in the inclined slide groove 2210 to cause the opening of the clamp 230 toward the magnetic fixing component 3 to gradually increase as well, reducing the binding force of the clamp 230 on the sleeve 232. This dynamic change greatly facilitates the adsorption process of the magnetic fixing component 3 onto the adsorption component 233, allowing the sleeve 232 to quickly and smoothly detach from the clamp 230.

[0045] Conversely, if the pushing component 5 pushes the sleeve 232 through the bracket 231 to move the plasma tube away from the magnetic fixing component 3, the clamp 230 will gradually tighten due to the gradually decreasing opening of the through groove 221. This design significantly enhances the stability of the clamp 230 on the plasma tube during the rotation of the support platform 2, ensuring the stability and safety of the plasma tube during operation.

[0046] The magnetic fastener 3 is located in the cavity 10. One end of the magnetic fastener 3 is inserted and fixed to the sealing mechanism 11. The magnetic fastener 3 faces multiple limiting members 23 respectively and is used to attract the plasma tube within a preset distance away from the limiting members 23.

[0047] Multiple color sensors 4 are fixed to the bottom of corresponding limiting members 23 to acquire the separation data and position of the plasma tube above. Specifically, the color sensors determine the color of an object by measuring the color and intensity of light reflected from its surface. During plasma separation, different components (such as plasma and red blood cells) will exhibit different colors. The color sensors 4 can identify these color differences, thereby determining the separation status of the plasma tube.

[0048] For example, blood plasma is usually pale yellow, while red blood cells are dark red. When a color sensor detects a color change in the blood plasma tube, such as a gradual change from dark red to pale yellow, it indicates that the separation of red blood cells from blood plasma has been completed.

[0049] If the sleeve 232 detaches from the bracket 231, the color sensor 4 will be unable to detect the change in color above or will be unable to detect the color data above, indicating that the sleeve 232 has detached from the bracket 231.

[0050] Multiple pushing components 5 are respectively arranged on the support platform 2, and are respectively arranged in correspondence with multiple limiting components 23. The driving end of the pushing component 5 is detachably connected to the corresponding limiting component 23, and is used to drive the limiting component 23 to move.

[0051] It should be noted that the pushing component 5 described in this embodiment is an electric cylinder, or a hydraulic rod, linear motor, or other components, which can be selected according to the actual situation.

[0052] The drive mechanism 6 is disposed in the cavity 10 and is fixed to the support platform 2 by the magnetic fastener 3. The drive mechanism 6 is used to drive the support platform 2 to rotate.

[0053] The controller 7 is mounted on the housing 1 and is connected to the color sensor 4, the pushing component 5 and the driving mechanism 6 respectively. It is used to control the pushing component 5 and the driving mechanism 6 according to the received separation data.

[0054] It should be noted that the controller 7 described in this embodiment is equipped with a display screen and control buttons. The display screen allows the operator to clearly understand the working status of the plasma separation device. The control buttons provide the operator with the ability to directly control and edit the program of the controller 7, facilitating flexible adjustments according to actual needs. Furthermore, the controller 7 can be wirelessly connected to the color sensor 4, the pushing component 5, and the drive mechanism 6. The wireless communication technology includes protocols such as Wi-Fi, Bluetooth, and ZigBee, thereby enabling remote control of the color sensor 4, the pushing component 5, and the drive mechanism 6 by remotely sending protocol commands through the controller 7.

[0055] Specifically, in the actual plasma separation process, initially, the limiting member 23 is positioned close to the magnetic fixing member 3. The operator inserts the plasma tube into the sleeve 232, using the sleeve 232 to initially limit and fix the plasma tube. Subsequently, by manipulating the pushing component 5, the limiting member 23 is driven to move the plasma tube away from the magnetic fixing member 3. During this process, the clamp 230 gradually tightens, providing secondary fixation for the plasma tube to ensure its stability during rotation. Multiple plasma tubes are then installed one by one using the same method.

[0056] After installing multiple plasma tubes, the sealing mechanism 11 is closed, and the drive mechanism 6 is activated. The drive mechanism 6 drives the support platform 2 to rotate, causing the centrifugal force generated by the plasma tubes to separate the plasma. It is worth noting that because the quality of the plasma in the multiple plasma tubes varies, the required separation time will also differ. Therefore, during the separation process, the color sensor 4 will detect the degree of separation of the corresponding plasma tube above in real time and send the generated separation data to the controller 7.

[0057] When the controller 7 determines that the separated color of the plasma tube reaches the preset standard, it indicates that the plasma separation in the plasma tube is complete. At this time, the controller 7 will control the drive mechanism 6 to stop running and record the angular position of the drive mechanism 6 after it stops rotating, to prevent the sleeves 232 from colliding with each other due to the same angle after subsequent rotation stops. At the same time, the controller 7 will control the push component 5 to drive the limiting component 23 to move towards the magnetic fixing component 3 according to a preset distance. When the distance between the limiting component 23 and the magnetic fixing component 3 is shortened to a certain range, the magnetic fixing component 3 can attract the sleeves 232 and the plasma tube on the limiting component 23, and at the same time, the adsorption component 233 will be attracted to the magnetic fixing component 3 to fix the sleeves 232.

[0058] Furthermore, if the color sensor 4 does not detect a color change during the separation process, it will send data to the controller 7. The controller 7 will then determine from this data that the sleeve 232 has detached from the support 231 and control the drive mechanism 6 to continue operating. This process is repeated to separate multiple plasma tubes. In this way, the separation time of different plasmas can be precisely controlled, improving the plasma separation effect and effectively avoiding unnecessary sample loss.

[0059] In one embodiment of the present invention, such as Figure 1 As shown, the drive mechanism 6 may include a motor 60, a mounting bracket 61, and multiple shock-absorbing legs 62.

[0060] The motor 60 is mounted on the mounting bracket 61.

[0061] It should be noted that the motor 60 is a geared motor with an encoder. The encoder can detect the rotation angle of the output shaft of the motor 60. That is, the motor 60 detects the rotation angle of its own output shaft through its own encoder, generates a first angle signal, and sends it to the controller 7 for recording. This is to avoid multiple sleeves 232 being attracted at the same position, which could cause potential collisions or interference.

[0062] Multiple shock-absorbing legs 62 have one end mounted on the bottom wall of the cavity 10, and the other end fixedly connected to the mounting bracket 61. The design of the multiple shock-absorbing legs 62 helps reduce vibration and noise generated during the operation of the motor 60. These shock-absorbing legs 62 effectively absorb and disperse vibration energy, preventing vibration from being transmitted to the bottom wall of the cavity 10 or other components. This not only improves the stability and durability of the device but also reduces the noise level during operation.

[0063] As a possible scenario, if the motor 60 wears out during long-term operation, and one plasma tube finishes centrifugation while the other plasma tubes continue to separate and rotate, if the rotor of the motor 60 becomes unbalanced, causing the device to shake, a balancing tube can be manually placed at the plasma tube after centrifugation to balance the device and reduce shaking.

[0064] In one embodiment of the present invention, such as Figure 1 As shown, the support platform 2 includes a collar 20, multiple support rods 21, and a support platform 22.

[0065] Among them, the collar 20 is sleeved on the output shaft of the motor 60, one end of the support rod 21 is fixed on the collar 20, and the other end of the support rod 21 is fixed on the support platform 22. The support platform 22 has a central hollow area 220, which is located in the central area of ​​the support platform 22, and multiple through slots 221 are arranged around the central hollow area 220.

[0066] Specifically, the above design allows the magnetic fastener 3 to be located among multiple adsorption components 233, and the adsorption components 233 can be adsorbed onto the magnetic fastener 3 from any angle. The motor 60 can drive the collar 20 to rotate through the locking force of the magnetic fastener 3, thereby driving the support platform 22 to rotate via the support rod 21 to generate centrifugal force.

[0067] In one embodiment of the present invention, such as Figure 1 As shown, the magnetic fastener 3 includes a threaded fastener 30, a one-way bearing 31, and a magnetic fastener 32.

[0068] One end of the threaded fastener 30 is threadedly connected to a threaded hole on the output shaft of the motor 60, and the other end of the threaded fastener 30 is fitted against the collar 20 to fix the collar 20 on the output shaft of the motor 60. The one-way bearing 31 is fixed on the threaded fastener 30. The magnetic suction member 32 passes through the central hollow area 220 of the support platform 2. One end of the magnetic suction member 32 is connected to the one-way bearing 31, and the other end of the magnetic suction member 32 is locked in the sealing mechanism 11.

[0069] It should be noted that the one-way bearing 31 is a type of bearing that can rotate freely in one direction and is locked in the other. During the rotation of the collar 20 driven by the motor 60, the one-way bearing 31 can rotate relative to the shaft of the magnetic attractor 32. The magnetic attractor 32 is restricted by the upper sealing mechanism 11, so only the one-way bearing 31 rotates and the magnetic attractor 32 does not rotate, thus ensuring the stability of the magnetic attractor 32 and preventing it from rotating. This ensures the stability of the adsorption component 233 when it is adsorbed onto the magnetic attractor 32. When the sealing plate 111 is lifted, the restriction on the magnetic attractor 32 is released, allowing the magnetic attractor 32 to rotate in the opposite direction. At this time, the magnetic attractor 32 and the one-way bearing 31 are locked, which can drive the threaded fastener 30 to rotate and release the restriction on the collar 20. The magnetic attractor 32 can be an electromagnet or a strong magnetic attractant.

[0070] Specifically, when the adsorption member 233 approaches the magnetic member 32, the two are attracted by magnetic force, and the magnetic member 32 can adsorb the adsorption member 233 onto itself.

[0071] Furthermore, such as Figure 5 As shown, a spline groove is provided at one end of the sealing plate 111 near the magnetic fastener 3, and a spline rod 330 is provided at one end of the magnetic fastener 3 near the spline groove. The spline rod 330 is inserted into the spline groove. That is, the spline rod 330 and the spline groove can limit the magnetic fastener 32, thereby preventing the magnetic fastener 32 from rotating when the support platform 2 rotates, thus ensuring the stability of the adsorption component 233 adsorbing onto the magnetic fastener 32.

[0072] In one embodiment of the present invention, such as Figure 1 , Figure 6 As shown, the plasma separation device also includes an inner liner 8 and a second sealing ring 9. The inner liner 8 has a folded edge 80, which is snapped onto the opening. The inner liner 8 extends into the cavity 10. The support platform 2 and the magnetic fixing member 3 are both disposed in the inner liner 8. A through hole is provided at the bottom of the inner liner 8. The second sealing ring 9 is installed at the through hole and is sleeved on the upper end cover of the motor 60.

[0073] It is understandable that by setting the inner liner 8 to cover the support platform 2 and the magnetic fastener 3, a clean and sterile environment can be ensured. Moreover, when the support platform 2 is removed, the inner liner 8 can be removed, which facilitates the thorough cleaning and disinfection of the inner liner 8, thereby maintaining the hygiene of the plasma separation device.

[0074] Meanwhile, the design of the folded edge 80, in conjunction with the first sealing ring 112, can increase the sealing between the top cover 110 and the shell 1. At the same time, the extrusion force can also be used to fix and limit the folded edge 80, and the folded edge 80 can also limit the position and height of the inner liner 8, thereby improving the stability of the inner liner 8 in the cavity 10.

[0075] In one embodiment of the present invention, such as Figure 7 As shown, a circular second groove 600 is provided on the outer wall of the upper end cover of the motor 60. The end of the second sealing ring 9 away from the inner liner 8 is fitted in the second groove 600, and the second groove 600 is higher than the bottom wall of the inner liner 8. The end of the collar 20 near the upper end cover of the motor 60 covers the upper end cover and the second sealing ring 9, and there is a gap between the collar 20 and the upper end cover of the motor 60. The second sealing ring 9 can increase the sealing between the upper end cover of the motor 60 and the inner liner 8. The fact that the second groove 600 is higher than the bottom wall of the inner liner 8 and that the end of the upper end cover of the motor 60 covers the upper end cover and the second sealing ring 9 are all for the purpose of allowing the blood plasma to collect on the inner liner 8 when blood plasma leaks, preventing blood plasma from flowing into the upper end cover of the motor 60 and reducing the service life of the motor 60.

[0076] In summary, the plasma separation device of this application embodiment can reasonably control the separation time of different plasmas, thereby improving the plasma separation effect and avoiding unnecessary sample loss.

[0077] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0078] The above description is merely a specific embodiment of the present invention, enabling those skilled in the art to understand or implement the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the present invention is not to be limited to the embodiments described herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A plasma separation device, characterized in that, include: A housing, wherein a cavity is provided inside the housing and an opening is provided on the cavity, and a sealing mechanism is hinged at the opening; A support platform is disposed in the cavity, and the support platform is provided with multiple slidingly connected limiting members for limiting and fixing the plasma tube; A magnetic fastener is disposed in the cavity. One end of the magnetic fastener is inserted and fixed to the sealing mechanism. The magnetic fastener faces multiple limiting members respectively and is used to attract and detach the plasma tube from the limiting members within a preset distance. Multiple color sensors are fixed to the bottom of the corresponding limiting member to obtain the separation data and position of the plasma tube above; Multiple pushing components are respectively disposed on the support platform and are arranged in a one-to-one correspondence with multiple limiting components. The driving end of each pushing component is detachably connected to the corresponding limiting component and is used to drive the limiting component to move. A drive mechanism is disposed in the cavity, and the drive mechanism is fixed to the support platform by a magnetic fastener. The drive mechanism is used to drive the support platform to rotate. A controller is disposed on the housing and is connected to the color sensor, the pushing component and the driving mechanism respectively, for controlling the pushing component and the driving mechanism according to the received separation data; The limiting component includes a clamp, a bracket, a sleeve, and an adsorption component, wherein, The support platform has multiple through slots arranged at equal angles, and the inner wall of each through slot has two sliding grooves. Both ends of the clamp are fixedly connected to the sliders in the corresponding grooves; The bracket is L-shaped and fixedly connected to the clamp; the bracket is detachably connected to the drive end of the pushing component. The cannula is secured in the clamp, and one end of the cannula is attached to the support. The cannula is used to accommodate the plasma tube. The adsorption element is disposed on the sleeve, and the adsorption element and the magnetic fixing element can be adsorbed and connected. The drive mechanism includes a motor, a mounting bracket, and multiple shock-absorbing legs, wherein, The motor is mounted on the mounting bracket; One end of each of the plurality of shock-absorbing legs is respectively installed on the bottom wall of the cavity, and the other end of each of the plurality of shock-absorbing legs is respectively fixedly connected to the mounting bracket; The support platform includes a collar, multiple support rods, and a support base, wherein, The collar is sleeved on the output shaft of the motor; One end of the support rod is fixed to the collar, and the other end of the support rod is fixed to the support platform; The support platform has a central hollow area, which is located in the central region of the support platform, and a plurality of through slots are arranged around the central hollow area. The magnetic fastener includes a threaded fastener, a one-way bearing, and a magnetic component. One end of the threaded fastener is threaded into a threaded hole on the motor output shaft, and the other end of the threaded fastener abuts against the collar to fix the collar on the motor output shaft. The one-way bearing is fixed to the threaded fastener; The magnetic suction component is inserted through the central hollow area of ​​the support platform. One end of the magnetic suction component is connected to a one-way bearing, and the other end of the magnetic suction component is locked in the sealing mechanism.

2. The plasma separation device according to claim 1, characterized in that, The through groove gradually widens from the direction of the pushing component toward the magnetic fastener, and the opening of the clamp faces toward the magnetic fastener.

3. The plasma separation device according to claim 1 or 2, characterized in that, It also includes an inner liner and a second sealing ring. The inner liner has a folded edge that is engaged at the opening, and the inner liner extends into the cavity. The support platform and the magnetic fastener are both disposed in the inner liner. The bottom of the liner has a through hole, the second sealing ring is installed in the through hole, and the second sealing ring is sleeved on the upper end cover of the motor.

4. The plasma separation device according to claim 3, characterized in that, A circular second groove is provided on the outer wall of the upper end cover of the motor. The end of the second sealing ring away from the inner liner is fitted in the second groove, and the second groove is higher than the bottom wall of the inner liner. The end of the collar near the upper cover of the motor covers the upper cover and the second sealing ring, and there is a gap between the collar and the upper cover of the motor.

5. The plasma separation device according to claim 3, characterized in that, The sealing mechanism includes an upper cover, a sealing plate, and a first sealing ring, wherein the upper cover is hinged to the opening, the first sealing ring is fixed on the folded edge, and the first sealing ring is in contact with the upper cover; The first sealing ring has a first groove, and the sealing plate is snapped and fitted between the first groove and the upper cover.

6. The plasma separation apparatus according to claim 5, characterized in that, The sealing plate has a spline groove at one end near the magnetic fastener, and the magnetic fastener has a spline rod at one end near the spline groove, with the spline rod inserted into the spline groove.

Images