Eutectic crystal of L-lysine and plant essential oil active ingredients as well as preparation method and application of eutectic crystal

Through eutectic technology, eugenol and cinnamaldehyde are combined with L-lysine, which solves the poor stability of the active ingredients of plant essential oils and the moisture absorption of L-lysine, achieving higher stability and antibacterial effects, and expanding the application field.

CN119661391AActive Publication Date: 2025-03-21TIANJIN UNIVERSITY OF TECHNOLOGY
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Patent Information

Application Number
CN202411607529.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-12
Publication Date
2025-03-21
Estimated Expiration
2044-11-12

AI Technical Summary

Technical Problem

The low melting point and high volatility of plant essential oil active ingredients such as eugenol and cinnamaldehyde lead to poor stability and difficulty in preservation, and L-lysine is prone to moisture absorption, resulting in inconvenience in processing and storage.

Method used

Through eutectic technology, the active ingredients of plant essential oils such as eugenol and cinnamaldehyde form stable eutectics with L-lysine, which changes the interaction between molecules and crystal accumulation methods, reduces hygroscopicity and volatility, and enhances stability.

Benefits of technology

The stability of the active ingredients of plant essential oils and the hygroscopicity of L-lysine is achieved, making eutectics more stable and effective in application, broadening its application field, and significantly improving the antibacterial effect on a variety of bacteria.

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Abstract

The invention relates to the technical field of compound eutectic crystals, and discloses an L-lysine and plant essential oil active component eutectic crystal and a preparation method and application thereof. The eutectic crystal is prepared from the following raw materials: L-lysine and plant essential oil active ingredients, the molar ratio of the L-lysine to the active ingredients of the plant essential oil is 1: 1; the active ingredient of the plant essential oil is at least one of eugenol and cinnamyl aldehyde. The eutectic crystal provided by the invention is formed by at least one of eugenol and cinnamyl aldehyde and L-lysine, is low in hygroscopicity and volatility and good in stability, and overcomes the defects that single L-lysine is strong in hygroscopicity and inconvenient to process and store, and single eugenol or cinnamyl aldehyde is strong in volatility and poor in stability; compared with single eugenol or cinnamyl aldehyde, the eugenol / cinnamyl aldehyde co-crystal shows lower minimum inhibitory concentration on various bacteria such as escherichia coli, staphylococcus aureus, salmonella enteritidis, candida albicans, nigmycin, aspergillus flavus and the like, and has a good antibacterial effect.
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