Imidazolone compound as well as preparation method and application thereof

By developing a new structure of imidazolone compounds, the problem of fewer target compounds for DNA damage repair in the prior art was solved, and the DNA damage repair ability and potential anti-tumor activity were achieved.

CN119661531AInactive Publication Date: 2025-03-21FORELAND PHARM CO LTD
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Patent Information

Application Number
CN202411849478.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-16
Publication Date
2025-03-21
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In the prior art, there are few target compounds for DNA damage repair, and it is difficult to effectively treat a variety of diseases.

Method used

A new structure of imidazolone compound was developed, and it was proved to have good DNA damage repair capabilities through in vitro activity experiments and is used for the treatment of various diseases.

Benefits of technology

This compound significantly enhances DNA damage repair capabilities, has potential anti-tumor activity, and can be used to treat a variety of diseases.

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Abstract

The invention discloses a heterocycloalkyl carboxylic acid compound, an intermediate and a preparation method and application thereof, and relates to the technical field of medicinal chemistry. The imidazolone compound provided by the invention has a structure as shown in a formula I or a formula II, and in-vitro activity experiments prove that the imidazolone compound has good DNA damage repair and can be used for treating various diseases. # imgabs0 #
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