Miniature handheld detection equipment

Abstract

The invention discloses a miniature handheld detection device which comprises an upper shell, a lower shell, a left cover plate and a right cover plate, a touch display screen is arranged on the upper shell, a mounting plate is mounted on the upper portion in the upper shell, an imaging mechanism, a code scanning head, an MCU control panel and an ARM plate are connected to the lower portion of the mounting plate, and a bottom plate is arranged in the lower shell. The bottom plate is provided with a micro servo direct-drive device which is in left-right transmission, a moving tray is arranged above the micro servo direct-drive device, a chip is inserted into the moving tray, and the bottom plate is provided with an electrode controller, a micro ultrasonic device and a light supplementing structure; the chip comprises a chip main body, and a microfluidic channel and an electrode are arranged on the chip main body. The miniature handheld detection equipment has the beneficial effects that the miniaturization of the miniature handheld detection equipment is realized, and the problem that the existing detection equipment is huge in size and can only be placed in a laboratory is effectively solved; the device can be used as portable equipment in clinic, can also be used in clinics, drugstores and other scenes, is low in production cost, and can be produced and popularized on a large scale.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, in particular to a miniature handheld detection device. Background Art

[0002] Biochemical analysis is one of the important means commonly used in clinical diagnosis. It measures various biochemical indicators by analyzing blood or other body fluids. Biochemical analyzers are instruments that use the principle of photoelectric colorimetry to measure a specific chemical component in body fluids. Due to their fast measurement speed, high accuracy, and low reagent consumption, they are now widely used in hospitals and epidemic prevention stations at all levels.

[0003] At present, the commonly used biochemical analysis instruments on the market are generally fully automatic wet biochemical analyzers, which drive the sample flow through the detection module through a pump, detect and count blood cells, etc. through a specific detection module, and then complete the sample detection. However, these biochemical analysis instruments for blood testing are currently huge in size and can only be placed in laboratories for use. They cannot be used as portable devices in clinical use or placed in clinics, pharmacies and other scenarios. At the same time, due to its huge structure and high cost, it can only be used in hospitals. It brings certain difficulties to people's medical treatment. Although many small analyzers have been produced, their structure still cannot be miniaturized, which is not convenient to carry and use, and their detection accuracy also needs to be considered. For example, a miniaturized medical detector and a miniaturized medical detection system disclosed in patent publication number CN205539015U. Summary of the invention

[0004] The object of the present invention is to provide a miniature handheld detection device to solve the problems raised in the above background technology.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a miniature handheld detection device, comprising an upper shell, a lower shell, a left cover plate and a right cover plate, wherein the upper shell, the lower shell, the left cover plate and the right cover plate are assembled into a rectangular box structure, the upper shell is provided with a touch display screen, a mounting plate is installed at the upper part of the upper shell, an imaging mechanism, a scanning terminal, an MCU control board and an ARM board are connected below the mounting plate, a bottom plate is provided in the lower shell, a micro servo direct drive device for left and right transmission is provided on the bottom plate, a moving tray is provided above the micro servo direct drive device, a chip is inserted on the moving tray, an electrode controller, a micro ultrasonic device and a fill light structure are installed on the bottom plate; the chip comprises a chip body, a microfluidic channel and an electrode are provided on the chip body, and the electrode controller is connected to the electrode.

[0006] Further preferably, the microfluidic channel comprises a sample loading hole, a capillary channel, a detection channel and a waste liquid channel connected in sequence from right to left, the detection channel is wider than the capillary channel, and the opening of the sample loading hole passes through the chip body upward. The sample loading hole is used for adding blood, and the capillary channel can absorb the blood in the sample loading hole into the capillary channel, so as to facilitate the control of blood flow through electrodes; the detection channel is used for the displacement and deformation of blood in it, so as to facilitate the imaging mechanism to capture the image information of blood cells in the blood; the waste liquid channel is used for collecting blood after detection.

[0007] Further preferably, the electrode comprises two electrodes a and two electrodes b, the two electrodes a and the two electrodes b are symmetrically arranged on the front and rear sides of the microfluidic channel, the electrodes a and the electrodes b are respectively connected to a plurality of contact wires with contact angles, the plurality of contact wires are arranged in an array on both sides of the capillary channel and the detection channel, and the chip body is provided with a wire groove for installing the contact wires. The electrodes a and the electrodes b can provide an alternating voltage to drive the blood to move through the current change, the contact angle is used to contact the microfluidic channel to achieve the driving of the blood in the microfluidic channel; the wire groove is used for the orderly arrangement of the contact wires.

[0008] Further preferably, the imaging mechanism comprises a first mounting structure, wherein a dichroic mirror a and a dichroic mirror b are arranged front and back in the first mounting structure, wherein the dichroic mirror a and the dichroic mirror b are arranged in an eight-shaped shape, wherein an upper light source is arranged above the dichroic mirror a, an objective lens is arranged below the dichroic mirror a, and an imaging CCD is arranged below the dichroic mirror b. The first mounting structure is used for mounting the dichroic mirror a, the dichroic mirror b, the upper light source, the objective lens, and the imaging CCD, and a reflective light path is formed by the dichroic mirror a and the dichroic mirror b, so that the detected fluorescent signal can be imaged through the objective lens and transmitted to the imaging CCD, and the dichroic mirror a and the dichroic mirror b can effectively separate the excitation light and the emission light, so as to prevent the emission light from interfering with the detection of the fluorescent signal.

[0009] Further preferably, the fill light structure includes a second mounting structure, wherein a lens group and a lower light source are disposed up and down in the second mounting structure, and the lens group is located directly below the objective lens. The second mounting structure is used for mounting the lens group and the lower light source, and the lower light source and the lens group form a fill light system, which can be turned on or off according to the requirements of the light and dark fields in accordance with different reagent detection items, so as to realize the capture of cell image information of blood cells in the blood.

[0010] Further preferably, the moving tray includes a substrate, on which two limit blocks are symmetrically arranged front and back, a limit plate is installed above each of the two limit blocks, and a through hole is provided on the substrate and located between the two limit blocks, and the through hole passes through the substrate from top to bottom. The substrate is used to support the chip, the limit blocks are used to limit the front and back positions of the chip, and the limit plate is used to limit the upper position of the chip, and the through hole facilitates the light emitted by the lower light source in the fill light structure to pass through and illuminate the blood in the chip.

[0011] Further preferably, at least one of the limit blocks is provided with a top block on the side close to the through hole, the top block is hemispherical, a spring is connected between the top block and the limit block, the top block is used to fix the position of the chip, and the spring provides an elastic force to the top block so that the top block can press the side of the chip to fix the position of the chip after insertion.

[0012] Further preferably, a plurality of limit posts are provided at the left end of the substrate for limiting the insertion of the chip on the moving tray; the micro servo direct drive device is a direct drive motor, which is connected to the substrate to drive the moving tray to move linearly left and right.

[0013] Further preferably, an interface adapter plate is connected below the mounting plate for installing various interfaces; an expansion interface and several USB interfaces are provided at the left end of the interface adapter plate, which can realize connection with other devices, import and export of data, fast charging, and connection to a power source, etc.

[0014] Further preferably, the left cover is provided with a battery compartment, in which a battery is installed, so that the miniature handheld detection device can work without a power source and can work as a portable device; the right cover is provided with a chip socket for inserting the chip into the moving tray.

[0015] Beneficial effects: The micro handheld detection device of the present invention realizes the miniaturization of the micro handheld detection device through a micro servo direct drive device, a micro ultrasonic device and a reflective imaging mechanism, and effectively solves the problem that the existing detection equipment is huge in size and can only be placed in the laboratory;

[0016] The micro-servo direct drive device can drive the chip and the blood inside it to move, and cooperate with the arrayed electrode structure and microfluidic channels on the chip to achieve accurate detection of blood cells in the blood; the scanning terminal is convenient for sample numbering and label entry;

[0017] The imaging mechanism realizes two light path reflections before reaching the imaging CCD, which can greatly shorten the imaging distance, realize the miniaturization setting of the imaging mechanism, and further reduce the size of the miniature handheld detection device;

[0018] By setting up the fill light structure, it can be used in conjunction with different reagent detection items, and can be turned on or off according to the requirements of the light and dark fields to capture the cell image information of blood cells in the blood;

[0019] This miniature handheld detection device can be used as a portable device in clinical practice, and can also be used in clinics, pharmacies and other scenarios. It has a low production cost and can be mass-produced and promoted. It can speed up the time people spend waiting for test results, improve the medical experience, and solve the problem of difficulty in seeking medical treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 A schematic diagram of the exploded structure of a miniature handheld detection device disclosed in an embodiment of the present invention;

[0021] Figure 2 This is a schematic diagram of the axial structure of a miniature handheld detection device disclosed in an embodiment of the present invention;

[0022] Figure 3 It is a schematic diagram of the main structure of the miniature handheld detection device disclosed in an embodiment of the present invention;

[0023] Figure 4 It is a schematic cross-sectional structural diagram of a miniature handheld detection device disclosed in an embodiment of the present invention;

[0024] Figure 5 A schematic diagram of the structure of a moving tray disclosed in an embodiment of the present invention;

[0025] Figure 6 A schematic diagram of the structure of a chip disclosed in an embodiment of the present invention;

[0026] Figure 7 Schematic diagram of the optical path of the imaging mechanism disclosed in the embodiment of the present invention.

[0027] Figure numerals: 1-upper shell, 2-lower shell, 3-left cover, 31-battery compartment, 4-right cover, 41-chip socket, 5-touch display screen, 6-mounting plate, 7-imaging mechanism, 71-first mounting structure, 72-dichroic mirror a, 73-dichroic mirror b, 74-upper light source, 75-objective lens, 76-imaging CCD, 8-scanning terminal, 9-MCU control board, 10-ARM board, 11-interface adapter board, 111-expansion interface, 112-USB interface, 12-bottom plate, 13-micro servo direct drive device, 14-motion tray, 141-base plate, 142-limiting block, 143-limiting plate, 144-through hole, 145-top block, 146-spring, 147-limiting column, 15-electrode controller, 16-micro ultrasonic device, 17-filling light structure, 171-second mounting structure, 172-lens group, 173-lower light source, 18-chip, 181-chip body, 182-microfluidic channel, 1821-sample loading hole, 1822-capillary channel, 1823-detection channel, 1824-waste liquid channel, 183-electrode, 1831-electrode a, 1832-electrode b, 184-wire slot. DETAILED DESCRIPTION

[0028] The following are specific embodiments of the present invention and the accompanying drawings to further describe the technical solution of the present invention, but the present invention is not limited to these embodiments.

[0029] like Figure 1-7 As shown, a miniature handheld detection device is used for detecting and counting blood cells in the blood. The miniature handheld detection device has a compact structure and small size. Its front-to-back width is 100mm, its height is 70mm, and its left-right length is 195mm. It is easy to hold and carry, and can be used as a portable device in clinical use, as well as in clinics, pharmacies and other scenarios. The miniature handheld detection device includes an upper shell 1, a lower shell 2, a left cover plate 3 and a right cover plate 4. The upper shell 1, the lower shell 2, the left cover plate 3 and the right cover plate 4 are assembled into a rectangular box structure for the installation and protection of various components. A touch screen 5 is provided on the upper shell 1 to facilitate the manual operation of the miniature handheld detection device at any time, parameter entry and detection data display. A mounting plate 6 is installed at the top of the upper shell 1, and an imaging mechanism 7, a scanning terminal 8, an MCU control board 9 and an ARM board 10 are connected below the mounting plate 6. A base plate 12 is provided in the lower shell 2, and a micro-servo direct-drive device 13 for left and right transmission is provided on the base plate 12. A moving tray 14 is provided above the micro-servo direct-drive device 13, and a chip 18 is inserted into the moving tray 14. An electrode controller 15, a micro-ultrasonic device 16 and a fill light structure 17 are installed on the base plate 12.

[0030] Among them, the mounting plate 6 is used for the installation of the imaging mechanism 7, the scanning terminal 8, the MCU control board 9 and the ARM board 10 in the rectangular box structure. The imaging mechanism 7 is used to capture the image information of the blood cells in the blood, and the imaging mechanism 7 can shorten the imaging distance and reduce the overall volume, so as to achieve the miniaturization of the handheld detection device. The scanning terminal 8 is used for barcode scanning. There is an NFC tag on the chip 18, which stores the chip serial number and the traceability code. The scanning terminal 8 scans the chip 18 being tested to realize the corresponding storage of the blood cell information of the tested blood, and displays it on the touch display screen 5 together with the test results, which is convenient for later reading and tracing. The MCU control board 9 is a micro control unit, which is used for the data processing of the automatic control box of each internal structure of the miniature handheld detection device; the ARM board 10 is suitable for the application of the MCU control board 9. As a core processor, it has the characteristics of high processing power and low power consumption, and can ensure the data display, processing and command input and output of the touch display screen 5. The micro-servo direct drive device 13 is used to drive the moving tray 14 to move horizontally left and right, and then move the chip 18 inserted on the moving tray 14 left and right, and move the blood on the chip 18 to the bottom of the imaging mechanism 7, so as to realize the blood detection on the chip 18. It is connected with the chip 18 through the electrode controller 15, drives the flow of blood through voltage changes, and cooperates with the imaging mechanism 7 to analyze the blood cells in the flowing blood, and finally obtains the detection results of the blood cells in the blood. The micro-ultrasonic device 16 is used to emit ultrasonic waves, which can emit high-frequency vibration sound waves to break up the blood, promote the movement of particles in the blood, separate some particles in the blood, effectively improve the detection effect of blood cells in the blood, and make the detection more accurate. The fill light structure 17 is used to fill the detection light of the imaging mechanism 7, and can cooperate with different reagent detection items, and choose to turn on or off according to the requirements of light and dark fields.

[0031] In the present application, the chip 18 includes a chip body 181, on which a microfluidic channel 182 and an electrode 183 are provided, and an electrode controller 15 is connected to the electrode 183. The chip body 181 is made of an insulating acrylic plate, which can facilitate the penetration of light, and facilitate the light from the upper and lower light sources to irradiate the microfluidic channel 182, thereby ensuring the capture of blood cell image information; the microfluidic channel 182 is used for the flow and detection of blood, and the electrode controller 15 controls the voltage change of the electrode 183, thereby controlling the movement of blood in the microfluidic channel 182, and through different combinations of blood movement, the deformation and displacement of blood can be controlled, thereby ensuring accurate analysis and detection of blood cells in the blood.

[0032] In the scheme of the present application, the microfluidic channel 182 includes a sample loading hole 1821, a capillary channel 1822, a detection channel 1823 and a waste liquid channel 1824 which are connected in sequence from right to left. The opening of the sample loading hole 1821 passes through the chip body 181 upward, wherein the sample loading hole 1821 is used for adding reagent particles and blood. The reagent particles can combine with specific cell components. After the combination, the illumination of a specific wavelength will have a fluorescence effect and stimulate light of another specific wavelength; the diameter of the capillary channel 1822 is very thin, and the blood can be sucked into it, so that the alternately powered electrode 183 can push the blood into the detection channel 1823. The width of the detection channel 1823 is greater than the capillary channel 1822, so that all the blood can enter the detection channel 1823 and deform and displace in the detection channel 1823, so that the imaging mechanism 7 can detect blood cells in the blood; the waste liquid channel 1824 is used for collecting blood after detection.

[0033] Based on the above scheme, the electrode 183 includes two electrodes a1831 and two electrodes b1832, and the two electrodes a1831 and the two electrodes b1832 are symmetrically arranged on the front and back sides of the microfluidic channel 182, and the electrodes a1831 and the electrodes b1832 are respectively connected to multiple contact wires with contact angles, and the multiple contact wires are arranged in an array on both sides of the capillary channel 1822 and the detection channel 1823. Among them, the electrode a1831 and the electrode b1832 can provide an alternating voltage, which is transmitted to the contact angle through the contact wire, and the blood droplets are attracted to move toward the electrode through the change of current, so as to realize the manipulation of blood, and facilitate the imaging mechanism 7 to accurately detect blood cells in the blood. A wire groove 184 for installing the contact wire is provided on the chip body 181, which is convenient for the arrangement of the contact wire and ensures that the arrangement of the contact wire is orderly.

[0034] In the solution of the present application, the imaging mechanism 7 includes a first mounting structure 71, a dichroic mirror a72, a dichroic mirror b73, an upper light source 74, an objective lens 75 and an imaging CCD76, wherein the first mounting structure 71 is a box structure, which is convenient for the installation of the dichroic mirror a72, the dichroic mirror b73, the upper light source 74, the objective lens 75 and the imaging CCD76; the dichroic mirror a72, the dichroic mirror b73, the upper light source 74, the objective lens 75 and the imaging CCD76 constitute the blood cell imaging optical path, which can greatly shorten the imaging distance, thereby reducing the overall volume of the miniature handheld detection device. The dichroic mirror can have the characteristics of selectively reflecting and transmitting light of a specific wavelength, can effectively separate the excitation light and the emission light, and prevent the emission light from interfering with the detection of the fluorescence signal. The dichroic mirror can project the excitation light onto the sample, while allowing the emitted fluorescence to pass smoothly, thereby improving the accuracy and sensitivity of the detection, and the dichroic mirror helps to improve the efficiency of the optical system. In the present application, the dichroic mirror a72 can accurately guide the excitation light from the upper light source 74 to the blood on the chip 18, and at the same time separate the weaker fluorescence emitted by the blood from the excitation light, so that the fluorescence signal can be clearly detected, and imaged by the objective lens 75, projected onto the imaging CCD 76 through the dichroic mirror a72 and the dichroic mirror b73 arranged in an eight-shaped shape, and captured as an electrical signal and transmitted to the touch display screen 5. Figure 7 As shown in FIG. 1 , the imaging optical path of the imaging mechanism 7 is shown. The working principle is as follows: an upper light source 74 is provided above the dichroic mirror a72, an objective lens 75 is provided below the dichroic mirror a72, and an imaging CCD 76 is provided below the dichroic mirror b73. Light a of a specific wavelength emitted by the upper light source 74 passes through the dichroic mirror a72 and the objective lens 75 and irradiates the chip 18. Reagent particles are pre-made on the chip 18, which are combined with blood. When irradiated by light a, there will be a fluorescence effect, which excites light b of another specific wavelength. Light b is imaged by the objective lens 75, and then projected onto the imaging CCD 76 through the dichroic mirror a72 and the dichroic mirror b73, and is captured as an electrical signal and transmitted to the touch screen 5.

[0035] Based on the above scheme, the fill light structure 17 includes a second mounting structure 171, and a lens group 172 and a lower light source 173 are arranged in the second mounting structure 171, and the lens group 172 is located directly below the objective lens 75. The second mounting structure 171 is used for installing the lens group 172 and the lower light source 173, and the lower light source 173 is used to emit specific light, and the lens group 172 is used to irradiate the light emitted by the lower light source 173 onto the blood on the chip 18. The lower light source 173 and the lens group 172 together constitute a fill light system, which is matched with different reagent detection items, and is selected to be turned on or off according to the requirements of the light field and the dark field. It is arranged in conjunction with the upper light source 74 of the imaging mechanism 7 to realize the capture of cell image information of blood cells in the blood.

[0036] In the solution of the present application, the moving tray 14 includes a substrate 141, a limit block 142, a limit plate 143 and a via 144, wherein two limit blocks 142 are symmetrically arranged on the substrate 141 for inserting and limiting the chip 18. The two limit blocks 142 can limit the front and rear positions of the chip 18, and the limit plate 143 can limit the upper position of the chip 18, so as to ensure that the chip 18 can be located at a specific position after insertion, and ensure that the blood in the chip 18 can be accurately detected. The via 144 runs through the substrate 141 from top to bottom, so that the light of the lower light source 173 can be irradiated on the blood in the chip 18.

[0037] Based on the above scheme, a top block 145 is provided on the side of at least one limit block 142 close to the through hole 144. The top block 145 is hemispherical. The top block 145 is used to auxiliary position and fix the chip 18 without hindering the insertion and removal of the chip 18. A spring 146 is connected between the top block 145 and the limit block 142. The spring 146 can always provide a rebound force to the top block 145, so that the top block 145 can always abut against the side of the chip 18, thereby ensuring the stability of the chip 18 when it is inserted into the moving tray 14 and ensuring the accurate detection of blood cells in the blood.

[0038] Based on the above scheme, a plurality of limit posts 147 are provided at the left end of the substrate 141 for limiting the insertion of the chip 18; the micro-servo direct-drive device 13 is a direct-drive motor, which is connected to the substrate 141 to drive the motion tray 14 to move left and right, so as to facilitate the insertion and transportation of the chip 18 to the set position. At the same time, the micro-servo direct-drive device 13 has a small structural volume and can effectively reduce the volume of the micro handheld detection equipment. The present application generates driving force through a magnetic field to realize the linear transportation of the direct-drive motor.

[0039] In the solution of the present application, an interface adapter board 11 is connected to the bottom of the mounting plate 6, and the interface adapter board 11 is used to realize the setting of the expansion interface 111 and the USB interface 112. The expansion interface 111 is used to transfer other devices, and the USB interface 112 is used for data import and export, connecting power supply and fast charging, etc.

[0040] In the present application, a battery compartment 31 is provided on the left cover plate 3 , in which a battery is installed, so as to facilitate the removal and replacement of the battery; a chip socket 41 is provided on the right cover plate 4 , so as to facilitate the insertion of the chip 18 into the moving tray 14 .

[0041] In this application, the workflow of the miniature handheld detection device is:

[0042] The blood to be tested is dripped into the microfluidic channel 182 through the sample injection hole 1821. The microfluidic channel 182 of the chip 18 contains pre-made reagent particles, and specific cells in the blood will combine with the actual particles;

[0043] The chip 18 is inserted into the limiting groove formed by the limiting block 142 and the limiting plate 13 of the moving tray 14. The micro-servo direct drive device 13 drives the moving tray 14 to move to the left to the set position, and acts as the electrode controller 15 to drive the blood in the microfluidic channel 182 to move from the capillary channel 1822 to the detection channel 1823. The blood cell image information in the blood is captured by the imaging mechanism 7 to detect the flowing blood.

[0044] The micro ultrasonic device 16 is started to break up the blood cells in the blood, and the image information of the blood cells in the blood in this state is captured by the imaging mechanism 7, and finally the captured new information is converted into an electrical signal by the MCU control board 9 and the ARM board 10 and transmitted to the touch screen 5, so as to realize the detection of the blood cells in the blood;

[0045] After the detection is completed, the blood in the microfluidic channel 182 is collected in the waste liquid channel 1824, and the micro-servo direct drive device 13 drives the moving tray 14 to move rightward to the set position, and the chip 18 is pulled out for unified processing.

[0046] In this application, the micro handheld detection device has a compact structure design. Through the close cooperation of various mechanisms and components, the purpose of miniaturization of the device is achieved, which effectively solves the problem that the existing detection equipment is huge in size and can only be placed in the laboratory. The micro handheld detection device can be used as a portable device in clinical practice, and can also be used in clinics, pharmacies and other scenarios. The production cost of the micro handheld detection device is low, and it can be mass-produced and promoted. It can speed up the time people wait for test results when seeing a doctor, improve the medical experience, and solve the problem of difficulty in seeking medical treatment.

[0047] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein with equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the invention content within the protection scope of the present invention.

Claims

1. A miniature handheld detection device, comprising an upper shell (1), a lower shell (2), a left cover plate (3) and a right cover plate (4), wherein the upper shell (1), the lower shell (2), the left cover plate (3) and the right cover plate (4) are assembled into a rectangular box structure, characterized in that: The upper shell (1) is provided with a touch screen (5), a mounting plate (6) is installed at the top of the upper shell (1), and an imaging mechanism (7), a scanning terminal (8), an MCU control board (9) and an ARM board (10) are connected below the mounting plate (6); a bottom plate (12) is provided inside the lower shell (2), and a left-right transmission micro-servo direct drive device (13) is provided on the bottom plate (12); a motion tray (14) is provided above the micro-servo direct drive device (13), and a chip (18) is inserted on the motion tray (14); an electrode controller (15), a micro-ultrasonic device (16) and a fill light structure (17) are installed on the bottom plate (12); the chip (18) comprises a chip body (181), and a microfluidic channel (182) and an electrode (183) are provided on the chip body (181), and the electrode controller (15) is connected to the electrode (183).

2. A miniature handheld detection device according to claim 1, characterized in that: The microfluidic channel (182) comprises a sample loading hole (1821), a capillary channel (1822), a detection channel (1823) and a waste liquid channel (1824) which are connected in sequence from right to left. The width of the detection channel (1823) is greater than that of the capillary channel (1822), and the opening of the sample loading hole (1821) passes through the chip body (181) upward.

3. A miniature handheld detection device according to claim 2, characterized in that: The electrode (183) comprises two electrodes a (1831) and two electrodes b (1832), the two electrodes a (1831) and the two electrodes b (1832) are symmetrically arranged on the front and back sides of the microfluidic channel (182), the electrode a (1831) and the electrode b (1832) are respectively connected to a plurality of contact wires with contact angles, the plurality of contact wires are arranged in an array on both sides of the capillary channel (1822) and the detection channel (1823), and a wire groove (184) for installing the contact wires is provided on the chip body (181).

4. A miniature handheld detection device according to claim 1, characterized in that: The imaging mechanism (7) comprises a first mounting structure (71), wherein a dichroic mirror a (72) and a dichroic mirror b (73) are arranged in a front-to-rear arrangement in the first mounting structure (71), wherein the dichroic mirror a (72) and the dichroic mirror b (73) are arranged in an eight-shaped arrangement, wherein an upper light source (74) is arranged above the dichroic mirror a (72), an objective lens (75) is arranged below the dichroic mirror a (72), and an imaging CCD (76) is arranged below the dichroic mirror b (73).

5. A miniature handheld detection device according to claim 4, characterized in that: The fill light structure (17) comprises a second mounting structure (171), wherein a lens group (172) and a lower light source (173) are arranged in the second mounting structure (171), and the lens group (172) is located directly below the objective lens (75).

6. A miniature handheld detection device according to claim 1, characterized in that: The moving tray (14) comprises a base plate (141), on which two limit blocks (142) are symmetrically arranged front and back, a limit plate (143) is installed above each of the two limit blocks (142), and a through hole (144) is provided on the base plate (141) and located between the two limit blocks (142), and the through hole (144) passes through the base plate (141) from top to bottom.

7. A miniature handheld detection device according to claim 6, characterized in that: A top block (145) is provided on the side of at least one of the limit blocks (142) close to the through hole (144); the top block (145) is hemispherical; a spring (146) is connected between the top block (145) and the limit block (142).

8. A miniature handheld detection device according to claim 6, characterized in that: A plurality of limiting columns (147) are provided at the left end of the base plate (141), and the micro servo direct drive device (13) is a direct drive motor connected to the base plate (141).

9. A miniature handheld detection device according to claim 1, characterized in that: An interface adapter plate (11) is connected below the mounting plate (6), and an expansion interface (111) and a plurality of USB interfaces (112) are provided at the left end of the interface adapter plate (11).

10. A miniature handheld detection device according to claim 1, characterized in that: The left cover plate (3) is provided with a battery compartment (31) in which a battery is installed, and the right cover plate (4) is provided with a chip socket (41).

Images