Compositions comprising self-tanning agent and certain sphingolipids and / or certain sphingosine bases

Abstract

The present invention relates to compositions comprising at least one self-tanning agent and certain sphingolipids and / or certain sphingosine bases.

Description

Field of the Invention

[0001] The present invention relates to compositions comprising at least one self-tanning agent and certain sphingolipids and / or certain sphingoid bases. Prior art

[0002] Substances such as ceramides have been used in cosmetics for decades.

[0003] There are products on the market that contain ceramide NP (ceramide III, N-oleoyl-phytosphingosine) and self-tanning agents.

[0004] However, so far, ceramides have not been found to have any special effects in the field of skin tanning.

[0005] It was an object of the present invention to provide substances which enhance the self-tanning effect in cosmetics.

[0006] Description of the invention

[0007] Surprisingly, it has been found that certain sphingolipids and certain sphingoid bases can enhance the tanning effect of self-tanning agents.

[0008] The present invention therefore provides a composition as claimed in claim 1 .

[0009] The present invention further provides the novel sphingolipid as claimed in claim 8.

[0010] One advantage of the present invention is that sphingolipids can improve the tanning effect of self-tanning agents without inducing the well-known UV damaging response that occurs through exposure of the skin to sunlight.

[0011] As an added benefit, the application of sphingolipids strengthens the barrier.

[0012] Another advantage of the present invention is that the addition of sphingolipids in self-tanning agents will reduce the negative effects of these molecular classes. For example, DHA is known to form formaldehyde in the skin after application. By adding sphingolipids, the concentration of self-tanning molecules such as DHA can be significantly reduced and side effects can be minimized.

[0013] Another advantage is that by adding sphingolipids, the skin tone will be more even and will not be as yellow as the classic self-tanning molecules are known for.

[0014] In addition, the self-tanning effect will last longer. Sphingolipids are highly effective active ingredients which already work at low concentrations.

[0015] Another advantage is better formulation stability, since sphingolipids build up a lamellar phase, which can help stabilize classic self-tanning molecules.

[0016] Another advantage of the present invention is that sphingolipids, especially the structures described in claim 8, will strengthen, regulate and balance the skin microbiota, which in turn contributes to a strong skin barrier and overall healthy skin that tans for a long time.

[0017] The present invention therefore provides a composition comprising

[0018] A) at least one self-tanning agent

[0019] B) At least one

[0020] Sphingolipids of Formula I

[0021]

[0022] in

[0023] R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H,

[0024] X is CH=CH, CH2-CH2 or CH2-HCOH, preferably CH2-HCOH, and

[0025] n is an integer selected from 3 to 8, preferably 6 to 7, most preferably 6,

[0026] and / or at least one

[0027] A sphingoid base selected from the group consisting of N-acetylphytosphingosine, phytosphingosine, sphingosine and dihydrosphingosine.

[0028] The sphingolipids of Formula I have multiple stereogenic centers, all of which are encompassed by Formula I.

[0029] Unless otherwise stated, all percentages (%) given are by mass.

[0030] Preferred compositions according to the invention are characterized in that at least one self-tanning agent is chosen from dihydroxyacetone and erythrulose.

[0031] Preferred compositions according to the invention are characterized in that the sphingolipids of the general formula I are selected from those wherein

[0032] R 1 It is H.

[0033] X is CH2-HCOH, and

[0034] n is selected from an integer of 6 to 7, most preferably 6.

[0035] Preferred compositions according to the invention are characterized in that A) is contained in an amount of 0.02 to 1.50 wt. %, preferably 0.03 to 1.00 wt. %, more preferably 0.05 to 0.50 wt. %, the weight percentages being based on the total composition.

[0036] Preferred compositions according to the invention are characterized in that B) is contained in an amount of 0.5 to 15.0 wt. %, preferably 1.0 to 10.0 wt. %, more preferably 3.0 to 6.0 wt. %, the weight percentages being based on the total composition.

[0037] The compositions according to the invention are preferably cosmetic preparations.

[0038] Cosmetic preparations containing self-tanning agents are frequently used by people who wish to avoid direct exposure of their skin to the UV rays of the sun, but who nevertheless wish to benefit from the advantages of a tan.

[0039] Preferred cosmetic preparations according to the invention therefore comprise at least one UV protection filter substance.

[0040] The UV protection filters used may be, for example, organic substances which are able to absorb UV radiation and then re-emit the absorbed energy in the form of longer-wave radiation, for example heat.

[0041] UVB filters can be oil-soluble or water-soluble. Examples of oil-soluble UVB photoprotective filters include:

[0042] 3-Benzalcamphor and its derivatives, for example 3-(4-methylbenzylidene)camphor,

[0043] 4-aminobenzoic acid derivatives, such as 2-ethylhexyl 4-(dimethylamino)benzoate and pentyl 4-(dimethylamino)benzoate,

[0044] Esters of cinnamic acid, for example 2-ethylhexyl 4-methoxycinnamate, isoamyl 4-methoxycinnamate, 2-ethylhexyl 2-cyano-3-phenylcinnamate (octocrylene),

[0045] Esters of salicylic acid, such as 2-ethylhexyl salicylate, 4-isopropylbenzyl salicylate, trimethylcyclohexyl salicylate,

[0046] Derivatives of benzophenone, for example 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone,

[0047] Esters of benzylidenemalonic acid, for example di-2-ethylhexyl 4-methoxybenzylidenemalonate,

[0048] triazine derivatives, for example 2,4,6-trianilino-(p-carbo-2'-ethyl-1'-hexyloxy)-1,3,5-triazine (octyl triazone) and those described in EP 1180359 and DE 2004 / 027475,

[0049] Propane-1,3-diones, for example 1-(4-tert-butylphenyl)-3-(4'-methoxyphenyl)propane-1,3-dione.

[0050] Suitable water-soluble UVB photoprotective filters include:

[0051] 2-Phenylbenzimidazole-5-sulfonic acid and its alkali metal, alkaline earth metal, ammonium, alkylammonium, alkanolammonium and glucose ammonium salts,

[0052] Sulfonic acid derivatives of benzophenone, for example 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid and its salts,

[0053] Sulfonic acid derivatives of 3-benzylidenecamphor, for example 4-(2-oxo-3-bornylidenemethyl)benzenesulfonic acid and 2-methyl-5-(2-oxo-3-bornylidene)sulfonic acid and salts thereof.

[0054] Suitable typical UVA photoprotective filters include, in particular, derivatives of benzoylmethane, such as 1-(4'-tert-butylphenyl)-3-(4'-methoxyphenyl)propane-1,3-dione or 1-phenyl-3-(4'-isopropylphenyl)propane-1,3-dione. Of course, mixtures of UV-A and UV-B filters can also be used.

[0055] In addition to the above-mentioned soluble substances, insoluble pigments are also suitable for this purpose, i.e. finely dispersed metal oxides or salts, for example titanium dioxide, zinc oxide, iron oxide, aluminum oxide, cerium oxide, zirconium oxide, silicates (talc), barium sulfate and zinc stearate. The particles here should have an average diameter of less than 100 nm, for example between 5 and 50 nm and in particular between 15 and 30 nm. They can be spherical in shape, but it is also possible to use particles with ellipsoidal shapes or particles with shapes that deviate from spherical shapes in other ways. A relatively new class of light protection filters is micronized organic pigments, for example 2,2'-methylenebis{6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol}, which has a particle size of <200 nm, which is available as, for example, a 50% aqueous dispersion.

[0056] Further suitable UV protection filters can be found in P. Finkel in -Journal 122, 543 (1996) was found in the review.

[0057] In conjunction with the preparations according to the invention, the preparations preferably comprise lipophilic, hydrophobic UV protection filter substances, in particular triazine derivatives.

[0058] Particular preference is given to using the following UV protection filter substances as UV-B filters: 2-ethylhexyl 2-cyano-3-phenylcinnamate, 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine, dioctylbutyramidotriazine, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, di-2-ethylhexyl 4-methoxybenzoate, 2,4, 6-tris-[anilino-(p-2'-ethyl-1'-hexyloxy)]-1,3,5-triazine, 2,4-bis[5,1(dimethylpropyl)benzoxazol-2-yl-(4-phenyl)imino]-6-(2-ethylhexyl)imino-1,3,5-triazine, 2,4-bis-{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine and 2-[4,6-bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl]-5-(octyloxy)phenol.

[0059] The UV-A filters used are preferably 1-(4'-tert-butylphenyl)-3-(4'-methoxyphenyl)propane-1,3-dione, 1-phenyl-3-(4'-isopropylphenyl)propane-1,3-dione.

[0060] A particularly preferred UV-A filter is 4-(tert-butyl)-4'-methoxydibenzoylmethane (CAS No. 70356-09-1), which is marketed by DSM under the brand name 1789 Sold and marketed by Merck under the trade name 9020, and hydroxybenzophenones according to DE 102004027475, particularly preferably 2-(4'-diethylamino-2'-hydroxybenzoyl)benzoic acid hexyl ester (also known as aminobenzophenone), which is available under the name Uvinul A Plus from BASF.

[0061] Further preferred UV filters are other so-called broadband filters, ie filters which absorb both UV-A and UV-B radiation. From this group, preference is given to using 2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol), which is marketed under the trade name M is available from Ciba Chemikalien GmbH, and 2-(2H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]phenol (CAS No. 155633-54-8), which has the INCI name Drometrizole Trisiloxane.

[0062] In addition to the two groups of primary UV protection filters mentioned above, secondary photostabilizers of the antioxidant type can also be used to block the photochemical reaction chain initiated when UV radiation penetrates the skin.

[0063] The cosmetic preparations according to the invention comprise UV protection filters in an amount of preferably 0.01 to 15% by weight, preferably 0.05 to 10% by weight, more preferably 0.1 to 5% by weight, based on the total preparation.

[0064] Preferably, the cosmetic preparations according to the invention comprise a combination of two or more different UV protection filters.

[0065] When both UVA and UVB photoprotective filters are used in the preparations according to the invention, the weight ratio of these filters is preferably from 1:2 to 1:4.

[0066] The formulation of the present invention may further comprise at least one additional component selected from the following group:

[0067] Emollients,

[0068] Emulsifiers,

[0069] Thickener / Viscosity Modifier / Stabilizer,

[0070] Antioxidants,

[0071] Hydrotropes (or polyols),

[0072] Solids and fillers,

[0073] Film formers,

[0074] Pearlescent additives,

[0075] Deodorant and antiperspirant actives,

[0076] Insect repellent,

[0077] preservative,

[0078] Conditioning agents,

[0079] essence,

[0080] dye,

[0081] Odor absorbers,

[0082] Cosmetic active substances,

[0083] Care additives,

[0084] Fat-enhancing agent,

[0085] Solvent.

[0086] Substances which can be used as exemplary representatives of the individual groups are known to the person skilled in the art and can be found, for example, in the German patent application DE 102008001788.4, which is hereby incorporated by reference and thus constitutes part of the present disclosure.

[0087] With regard to further optional components and the amounts of these components to be used, reference is expressly made to the relevant handbooks known to the person skilled in the art, for example K. Schrader, “Grundlagen und Rezepturen der Kosmetika” [Fundamentals and formulations of cosmetics], 2nd edition, pages 329 to 341, Hüthig Buch Verlag Heidelberg.

[0088] The amount of each additive is guided by the intended use.

[0089] Typical framework formulations for specific applications are known in the prior art and are contained, for example, in the manufacturer's manuals for specific base materials and active ingredients. These existing formulations can usually be adopted intact. However, if necessary, for the purpose of adjustment and optimization, the required modifications can be carried out in a straightforward manner by simple experiments.

[0090] The present invention further provides a sphingolipid of formula Ib

[0091]

[0092] in

[0093] R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H,

[0094] X is CH2-HCOH, and

[0095] n 6,

[0096] or among them

[0097] R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H,

[0098] X is CH=CH or CH2-HCOH, preferably CH2-HCOH, and

[0099] n 5.

[0100] It has been found that the sphingolipids of formula Ib are the most effective in enhancing the self-tanning effect.

[0101] The present invention further provides a composition, preferably a cosmetic preparation comprising a sphingolipid of the general formula Ib. These cosmetic preparations according to the invention comprise a sphingolipid of the general formula Ib in the preferred manner as described above for component A) of the composition according to the invention.

[0102] The invention further provides a sphingolipid of the general formula Ib for use as a medicament.

[0103]

[0104] in

[0105] R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H,

[0106] X is CH2-HCOH, and

[0107] n 6,

[0108] or among them

[0109] R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H,

[0110] X is CH=CH or CH2-HCOH, preferably CH2-HCOH, and

[0111] n 5,

[0112] The present invention further provides the use of the sphingolipids of formula Ib for treating acne, atopic dermatitis, psoriasis, herpes, warts, rosacea, skin cancer, pemphigus, alopecia, epidermolysis bullosa, scleroderma, ichthyosis, vitiligo and / or Raynaud's phenomenon.

[0113]

[0114] in

[0115] R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H,

[0116] X is CH2-HCOH, and

[0117] n 6,

[0118] or among them

[0119] R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H,

[0120] X is CH=CH or CH2-HCOH, preferably CH2-HCOH, and

[0121] n 5,

[0122] The present invention further provides the use of at least one sphingolipid of the general formula I and / or at least one sphingosine base selected from N-acetylphytosphingosine, phytosphingosine, sphingosine and dihydrosphingosine for enhancing the self-tanning effect of a self-tanning agent

[0123]

[0124] in

[0125] R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H,

[0126] X is CH=CH, CH2-CH2 or CH2-HCOH, preferably CH2-HCOH, and

[0127] n is an integer selected from 3 to 8, preferably 6 to 7, most preferably 6,

[0128] The invention further provides the use of at least one composition according to the invention for tanning human skin.

[0129] Preferably, in the use according to the invention, the same preferred components A) and B) are used in the same preferred embodiments as described above for the compositions according to the invention.

[0130] The use of the invention is cosmetic use, not medical use.

[0131] The examples given below illustrate the invention by way of example without any intention of limiting the invention to the embodiments specified in the examples, the scope of application of the invention being apparent from the entire description and claims. Example

[0132] Example 1: Enhanced Self-Tanning DHA

[0133] Experiments according to the present invention are marked with *.

[0134] The following test was conducted on 8 groups of 10 people each.

[0135] The formulation containing DHA was applied to the left forearm, while the formulation containing DHA and a potential enhancer compound was applied to the right forearm.

[0136]

[0137] Ceramide NP C13: Formula I, wherein R 1 =H, X=CH=CH, n=5

[0138] Ceramide NP C15: Formula I, wherein R 1 =H, X = CH2-HCOH, n = 6

[0139] Ceramide NP C17: Formula I, wherein R 1 =H, X = CH2-HCOH, n = 7

[0140] Repeat the treatment daily for one week (2.5 ml per side).

[0141] The degree of tanning was assessed on a scale of 0 (no effect) to 5 (very strong tanning).

[0142] The average values ​​are given in the table below.

[0143] group 1 2 3 4 5 6 7 8 Preparation 1 1.9 2.1 2.1 2.0 2.1 2.1 1.9 1.9 Preparation 2 1.9 Preparation 3 2.1 Preparation 4 2.0 Preparation 5* 2.9 Preparation 6* 2.6 Preparation 7* 2.3 Preparation 8* 2.4 Preparation 9* 2.8

[0144] As can be seen above, only ceramides and spingoid bases with odd numbers of carbon atoms can enhance the self-tanning effect.

[0145] Example 2: Enhanced Self-Tanning Erythrulose

[0146] The data was generated similarly to Example 1, but using erythrulose instead of DHA:

[0147]

[0148]

[0149] The average values ​​are given in the table below.

[0150] group 8 9 10 Preparation 9 1.2 1.3 1.2 Preparation 10 1.3 Preparation 11* 2.1 Preparation 12* 1.9

[0151] As can be seen above, only ceramides with an odd number of carbon atoms can enhance the self-tanning effect.

[0152] Example 3: Example Formulation

[0153] Facial Cream I

[0154]

[0155]

[0156] Preparation: Heat phases A and B to 85°C. Add phase A to B while stirring. Homogenize. Cool to 40°C while stirring. Add phases C and D. Cool to 30°C while stirring.

[0157] Face Cream II

[0158]

[0159]

[0160] Preparation: Heat phases A and B to 85°C. Add phase A to B while stirring. Homogenize. Cool to 40°C while stirring. Add phases C and D. Cool to 30°C while stirring.

[0161] Face Cream III

[0162]

[0163]

[0164] Preparation: Heat phases A and B to 85°C. Add phase A to B while stirring. Homogenize. Cool to 40°C while stirring. Add phases C and D. Cool to 30°C while stirring.

[0165] O / W lotion, skin care lotion

[0166]

[0167]

[0168] preparation:

[0169] Heat phases A and B to 85°C. Add phase A to phase B while stirring. Homogenize. Cool to about 40°C while stirring gently and add phase C. Homogenize briefly. Add phases D and E gradually.

[0170] Enjoy Sunscreen Lotion, SPF 50

[0171]

[0172]

[0173] preparation:

[0174] Heat phases A and B separately to about 85°C. Add phase A to B. Homogenize. Cool to about 50°C with gentle stirring, then add phase C. Homogenize. Cool to about 35°C with gentle stirring, then add phases D, E and F. Homogenize. Adjust the pH to 6.5-7.0 with phase E.

[0175] Microemulsion

[0176]

[0177] preparation:

[0178] Heat phase B to about 85°C until ceramide NP C15 and ceramide NP C17 are visibly dissolved, respectively. Slowly add phase B to phase A (20-22°C) while stirring. Add phases C, D and E. Adjust pH to pH 5-5.5 with phase F.

[0179] Facial Oil

[0180]

[0181] preparation

[0182] Mix the ingredients in the order given and heat to 85°C. Stir slowly until a clear solution is obtained. Cool.

[0183] Facial Cleanser

[0184]

[0185] preparation

[0186] Heat phase B to a maximum of 85°C with stirring. Cool to room temperature. Add phase A to phase B with gentle stirring. Disperse xanthan gum in water to prepare phase C. Add phase C gradually and slowly with stirring. Adjust pH to between 5.0 and 5.5 with phase D.

[0187] Shampoo

[0188]

[0189] preparation:

[0190] Heat sodium laureth sulfate, dermofeel sensolv MB, dermofeel G10 LW 70MB, ceramide NP C15, and ceramide NP C17 to 85°C until the solution is clear. Add the other ingredients stepwise in the given order. Cool to 30°C while stirring.

[0191] Oral care (mouthwash)

[0192]

[0193] preparation

[0194] Heat RHEANCE One and Ceramide NP C15 and Ceramide NP C17 to 85°C. Cool to 40°C. Dissolve flavor. Slowly add water while stirring, then add the remaining ingredients in the order given.

[0195] Deodorant preparations (natural emulsion deodorant roll-on

[0196]

[0197] preparation

[0198] Heat phase A up to 80°C and disperse phase B in A. Heat phase C separately up to 85°C. Add phase C to phase A / B. Cool to 35°C and add phase D in the given order with slow stirring. Add phase E to adjust the pH.

[0199] body wash

[0200]

[0201]

[0202] preparation

[0203] Heat sodium laureth sulfate, Verstatil PC, ANTIL SOFT SC MB, ceramide NPC15, and ceramide NP C17 to 85°C. While stirring, gradually add other ingredients.

[0204] Facial mask

[0205]

[0206] preparation

[0207] Heat phases A and B to 85°C. Add phase A to B while stirring. Homogenize. Cool to 50°C while stirring gently. Add phase C at about 50°C. Homogenize again briefly. Cool to about 35°C while stirring gently. Prepare phase D. Add phase D while stirring. Adjust the pH to 4.0-5.0 with phase E.

[0208] Conditioner

[0209]

[0210] preparation

[0211] Heat phases A and B to 85°C. Add phase B to phase A without stirring. Homogenize. Cool to 30°C while stirring.

[0212] W / O Emulsion

[0213]

[0214] preparation

[0215] Heat phase A to about 85°C. Slowly add phase B (80°C or room temperature) while stirring. Homogenize briefly. Cool to below 30°C with gentle stirring and homogenize again.

[0216] 20.1 Sensitive Skin Care Cream

[0217] A 1.50 wt% Care 450MB (Polyglyceryl-3 Methylglucose Distearate)

[0218] 0.50% by weight Care XL 80MB (Bis-PEG / PPG-20 / 5PEG / PPG-20 / 5 Dimethicone; Methoxy PEG / PPG-25 / 4 Dimethicone; Caprylic / Capric Triglyceride)

[0219] 1.50 wt% stearyl alcohol

[0220] 2.50 wt% M Pellets MB (Glyceryl Stearate)

[0221] 6.50 wt% M(Isopropyl myristate)

[0222] 4.80 wt% APM (PPG-3 Myristyl Ether)

[0223] 0.50% by weight MM MB (Myristyl Myristate)

[0224] 0.10 wt% Ceramide NP 15

[0225] 0.10 wt% SPHINGOKINE NP (hexanoyl phytosphingosine)

[0226] B 1.00 wt% Natural Betaine (Betaine)

[0227] 3.00 wt% glycerol

[0228] Add to 100 wt% water

[0229] C 0.20 wt% Carbomer

[0230] 0.10 wt% xanthan gum

[0231] 0.80 wt% M(Isopropyl myristate)

[0232] D qs Sodium hydroxide (10% in water)

[0233] 1.00 wt% PC (phenoxyethanol; caprylyl glycol)

[0234] QS Fragrance

[0235] 20.2 Masks for reactive skin

[0236] A 0.50wt% Care XL 80MB (Bis-PEG / PPG-20 / 5PEG / PPG-20 / 5 Dimethicone; Methoxy PEG / PPG-25 / 4 Dimethicone; Caprylic / Capric Triglyceride)

[0237] 1.50 wt% 350(Polydimethylsiloxane)

[0238] 4.00 wt% OS(Ethylhexyl Stearate)

[0239] 4.00 wt% CT MB (Caprylic / Capric Triglyceride)

[0240] 0.10 wt% Ceramide NP 15

[0241] B 0.60 wt% Carbomer 341ER (Acrylates / C10-30 Alkyl Acrylate Crosspolymer)

[0242] 0.10 wt% (Sodium Hyaluronate)

[0243] 0.10 wt% 50(Hydrolyzed Hyaluronic Acid)

[0244] 5.00 wt% glycerol

[0245] Add to 100 wt% water

[0246] C 1.00wt% PC (phenoxyethanol; caprylyl glycol)

[0247] D qs Sodium hydroxide (10% in water)

[0248] 20.3 Microbial Balance Essence

[0249] A 0.30 wt% Carbomer 341ER (Acrylates / C10-30 Alkyl Acrylate Crosspolymer)

[0250] Add to 100 wt% water

[0251] B qs Sodium hydroxide (10% in water)

[0252] C 1.00wt% SML 20MB (Polysorbate 20)

[0253] 0.10 wt% Ceramide NP 15

[0254] D 3.00 wt% InuMax Advanced Retinol (Water; Caprylic / Capric Triglyceride; Glycerin;

[0255] Polysorbate 20; Retinol; Inulin Lauryl Carbamate; Behentrimonium Chloride; Sucrose Laurate; BHT; BHA; Phenoxyethanol; Benzoic Acid; Dehydroacetic Acid; Ethylhexylglycerin; Disodium EDTA)

[0256] E 2.00 wt% PC (phenoxyethanol; caprylyl glycol)

[0257] 20.4 Skin Balancing Cream

[0258] A added to 100 wt% deionized water

[0259] 2.00 wt% Glycerol 99.5%, European Pharmacopoeia (Glycerol)

[0260] 0.10 wt% PA-3 (sodium phytate; water; alcohol)

[0261] A1 0.30 wt% Xanthan Gum FEDCS-PC (Xanthan Gum)

[0262] B 1.00 wt% Feel C 10 (cellulose)

[0263] 6.00 wt% muls GC MB (Glyceryl Stearate Citrate; Cetearyl Alcohol; Glyceryl Caprylate)

[0264] 6.00 wt% DC MB (Deca Cocoate)

[0265] 2.00 wt% decalact sebum MB (polyglyceryl-10 laurate; sodium caproyl / lauroyl lactylate; glycerin, saw palmetto (Serenoa Serrulata) fruit extract; juniper (Juniperus Communis) fruit extract)

[0266] 0.10 wt% Toco 70 non GMO (tocopherol; sunflower seed oil)

[0267] 0.05 wt% Ceramide NP 15

[0268] 0.05 wt% SPHINOX Defenda (Hydroxybutyrylphytosphingosine)

[0269] 0.1% TEGO Sterol 7-DHC (7-dehydrocholesterol)

[0270] C 3.00 wt% 1388eco(glycerin; water; sodium levulinate; sodium anisate)

[0271] 0.15 wt% flavor

[0272] 20.5 Moisturizing Lip Mask

[0273] A 0.02 wt% (Sodium Hyaluronate)

[0274] 9.96 wt% glycerol

[0275] Add to 100 wt% water

[0276] 0.02 wt% Rouge Covarine W 3799 (CI12490; water; glycerin)

[0277] 0.02 wt% Rouge Covarine W 3799 (CI12490; water; glycerin)

[0278] B 8.00 wt% DC MB (Deca Cocoate)

[0279] 2.00 wt% OER MB (Oleyl Erucate)

[0280] 3.00 wt% MM MB (Myristyl Myristate)

[0281] 7.00 wt% P(Isopropyl Palmitate)

[0282] 3.00 wt% GPS (Polyglyceryl-4 diisostearate / polyhydroxystearate / sebacate)

[0283] 6.00 wt% SH MB (Stearyl Heptanoate)

[0284] 1.00 wt% white beeswax

[0285] 10.00 wt% Candelilla wax (Candelilla Cera)

[0286] 3.00 wt% Carnauba wax

[0287] 3.50 wt% Shea (Butyrospermum Parkii) Oil

[0288] 33.49 wt% SAT-Y-338073 (yellow iron oxide)

[0289] 33.49 wt% Schercemol PTID Ester (Triisostearyl Polyglyceryl-3 Dimer Dilinoleate)

[0290] 0.10 wt% Ceramide NP 15

[0291] 2.00 wt% Filler CL MB (Water; Ethylhexyl Stearate; Sodium Hyaluronate Crosspolymer; Polyglyceryl-4 Diisostearate / Polyhydroxystearate / Sebacate; Sodium Isostearate)

[0292] 20.6. Sleeping mask for treating photoaged skin

[0293] A 0.50wt% Care XL 80MB (Bis-PEG / PPG-20 / 5PEG / PPG-20 / 5 Dimethicone; Methoxy PEG / PPG-25 / 4 Dimethicone; Caprylic / Capric Triglyceride)

[0294] 1.50 wt% Wax 9840 (Cetyl Dimethicone)

[0295] 4.00 wt% OS(Ethylhexyl Stearate)

[0296] 4.00 wt% CT MB (Caprylic / Capric Triglyceride)

[0297] 0.10 wt% Ceramide NP 15

[0298] 3.00 wt% CBD Revitalize (Amaranthus Caudatus Seed Extract (and) Cholesterol (and) Glyceryl Caprylate)

[0299] B added to 100 wt% water

[0300] 5.00 wt% glycerol

[0301] 0.05 wt% KELCOGEL CG-HA (gellan gum)

[0302] 0.40 wt% Carbomer (Carbomer Homopolymer C)

[0303] C 2.00 wt% Natural Betaine (Betaine)

[0304] 0.50% by weight Turmerone (Turmeric Root Extract)

[0305] D qs Sodium hydroxide (10% in water)

[0306] E 0.80 wt% PC (phenoxyethanol; caprylyl glycol)

[0307] 20.7 Anti-Cellulite Body Mask

[0308] B added to 100 wt% deionized water

[0309] 4.50% by weight Glycerol 99.5%, European Pharmacopoeia (Glycerol)

[0310] 0.10 wt% PA-3 (sodium phytate; water; alcohol)

[0311] 0.80 wt% Xanthan Gum FEDCS-PC (xanthan gum)

[0312] B 5.00 wt% Vegetable Squalane, Refined, Olive-Based (Squalane)

[0313] B1 8.00 wt% muls GC MB (Glyceryl Stearate Citrate; Cetearyl Alcohol; Glyceryl Caprylate)

[0314] 2.00 wt% M Pellets MB (Glyceryl Stearate)

[0315] 2.00 wt% KahlWax 8104 (white beeswax)

[0316] 2.00 wt% KahlWax 6614 (Camellia oleifera leaf extract)

[0317] 2.00 wt% Shea Butter, Refined, Organic (Shea Butter) (Butyrospermum Parkii Butter)

[0318] 5.00 wt% almond oil, refined (sweet almond oil)

[0319] 3.00 wt% Avocado oil, refined (Persea Gratissima oil)

[0320] 2.00 wt% Apricot kernel oil, refined (Apricot kernel oil)

[0321] 0.20 wt% Toco 70 non GMO (tocopherol; sunflower seed oil)

[0322] 0.10 wt% Ceramide NP 15

[0323] 1.00 wt% TocoSkin (tocopherol; sunflower seed oil)

[0324] C 0.50wt% Turmerone (Turmeric Root Extract)

[0325] 0.50 wt% Pumpkin Seed (Kürbiskern) Organic Extract P-00025487 (Sunflower Hybrid Oil; Pumpkin Seed Extract; Rosemary Leaf Extract)

[0326] 3.5 wt% 1388eco NaL (glycerol, water, sodium levulinate, p-anisic acid, sodium hydroxide)

[0327] D 1.00 wt% MB (ceramide NP; ceramide NG; ceramide EOS; ceramide EOP; ceramide AP; hexanoyl phytosphingosine; hexanoyl sphingosine; behenic acid; cholesterol; ceteareth-25; glycerin; cetyl alcohol; phenoxyethanol; ethylhexylglycerin; tocopherol; ascorbyl palmitate; lecithin; glyceryl stearate; glyceryl oleate; citric acid; water)

[0328] 20.8 Aftershave Soothing Essence

[0329] A added to 100 wt% deionized water

[0330] 0.10 wt% PA-3 (sodium phytate; water; alcohol)

[0331] 3.00 wt% OM (Methylpropanediol; Caprylyl Glycol)

[0332] 5.00 wt% Glycerol 99.5%, European Pharmacopoeia (Glycerol)

[0333] B 2.50 wt% prot V MB (hydrolyzed vegetable protein; sodium citrate; magnesium stearate; xanthan gum)

[0334] 0.50% by weight M Pellets MB (Glyceryl Stearate)

[0335] 4.00 wt% DC MB (Deca Cocoate)

[0336] 0.50 wt% vegetable squalane (squalane)

[0337] 1.00 wt% Feel C 10 (cellulose)

[0338] 0.20 wt% Toco 70 non GMO (tocopherol; sunflower seed oil)

[0339] 2.00 wt% decalact sebum MB (polyglyceryl-10 laurate; sodium caproyl / lauroyl lactylate; glycerin, saw palmetto fruit extract; juniper berry extract)

[0340] 0.10 wt% Ceramide NP 15

[0341] 0.10 wt% Phytosphingosine

[0342] C 3.00 wt% Denatured ethanol (denatured alcohol)

[0343] 20.9 Hair and Scalp Serum

[0344] A 2.00 wt% Care LTP MB (Sorbitan Laurate; Polyglyceryl-4 Laurate; Dilauryl Citrate)

[0345] 2.67 wt% CT MB (Caprylic / Capric Triglyceride)

[0346] 1.33 wt% sensolv MB (isoamyl laurate)

[0347] 1.00 wt% (Ceramide NG; Olea europaea (olive) fruit oil; Ricinus communis (castor) seed oil)

[0348] 0.10 wt% Ceramide NP 15

[0349] 0.05% (Sphingosine)

[0350] B added to 100 wt% water

[0351] 3.00 wt% glycerol

[0352] C 2.00 wt% sensolv MB (isoamyl laurate)

[0353] 0.10 wt% Carbomer (Carbomer Homopolymer A)

[0354] 0.10 wt% Acrylates / C10-C30 Alkyl Acrylate Crosspolymer (Carbomer Copolymer C)

[0355] D 2.00 wt% water

[0356] 0.005 wt% Pep 3-Boost (Copper Tripeptide 34)

[0357] E 1.00 wt% PC (phenoxyethanol; caprylyl glycol)

[0358] qs Sodium hydroxide (10% in water)

[0359] 20.10 Anti-Aging Low Viscosity Facial Serum

[0360] A 3.00 wt% Care PBS 6MB (Polyglyceryl-6 Stearate (and) Polyglyceryl-6 Behenate)

[0361] 0.50% by weight M Pellets MB (Glyceryl Stearate)

[0362] 4.00 wt% DEC (Diethylhexyl carbonate)

[0363] 5.00 wt% XC MB (phenoxyethyl caprylate)

[0364] 3.00 wt% sensolv MB (isoamyl laurate)

[0365] 3.00 wt% SP 13-1MB (Poly C10-30 Alkyl Acrylate)

[0366] 0.10 wt% Ceramide NP 15

[0367] 0.05 wt% Salicyloyl phytosphingosine SLC (Salicyloyl phytosphingosine)

[0368] B added to 100 wt% water

[0369] 3.00 wt% glycerol

[0370] 0.20 wt% Carbomer (Carbomer Homopolymer A)

[0371] 0.10 wt% 50(Hydrolyzed Hyaluronic Acid)

[0372] C qs Sodium hydroxide (10% in water)

[0373] D 0.50 wt% BeautiFerm Healerine (water; Ganoderma lucidum extract; glycerin; propylene glycol; xanthan gum; 1,2-hexanediol; caprylyl glycol)

[0374] E 1.00 wt% PC (phenoxyethanol; caprylyl glycol)

[0375] Z qs flavor

[0376] 20.11 Anti-Acne Essence

[0377] A 2.00 wt% AC MB (Isoamyl Cocoate)

[0378] 2.00 wt% OER MB (Oleyl Erucate)

[0379] 1.00 wt% Octyldodecanol

[0380] 1.00 wt% APM (PPG-3 Myristyl Ether)

[0381] 0.50% by weight Turmerone (Turmeric Root Extract)

[0382] 0.05 wt% Ceramide NP 15

[0383] 0.07 wt% (Sphingosine)

[0384] B 0.50 wt% Carbomer 341ER (Acrylates / C10-30 Alkyl Acrylate Crosspolymer)

[0385] 5.00 wt% glycerol

[0386] 3.00 wt% alcohol

[0387] Add to 100 wt% water

[0388] C qs Sodium hydroxide (10% in water)

[0389] Z qs preservatives

[0390] 20.12 O / W Aftershave cream for irritated skin

[0391] A 1.5 wt% C 62 Pellets MB (Citrate Glycerides)

[0392] 2.0 wt% M Pellets MB (Glyceryl Stearate)

[0393] 3.0 wt% Cetearyl alcohol 1618MB

[0394] 3.5 wt% TN(C12-15 Alkyl Benzoate)

[0395] 2.0 wt% CR MB (Cetyl Ricinoleate)

[0396] 1.0 wt% triisostearin

[0397] 0.5 wt% MM MB (Myristyl Myristate)

[0398] 4.0 wt% Cyclopentasiloxane

[0399] 2.0 wt% Macadamia ternifolia seed oil

[0400] 0.5 wt% Tocopheryl Acetate

[0401] 0.10 wt% Ceramide NP 15

[0402] 0.10 wt% Olive(Ceramide NP)

[0403] B 4.0 wt% glycerol

[0404] 0.5 wt% Panthenol

[0405] 0.2 wt% Allantoin

[0406] Add to 100 wt% water

[0407] C 0.3 wt% Carbomer (Carbomer Homopolymer B)

[0408] 1.2 wt% TN(C12-15 Alkyl Benzoate)

[0409] D 0.5 wt% Bisabolol

[0410] E qs Sodium hydroxide (10% in water)

[0411] F 7.0 wt% alcohol

[0412] G 0.7 wt% Euxyl PE 9010 (phenoxyethanol, ethylhexylglycerin) Z qs fragrance

[0413] 20.13 After Sun Gel

[0414] A 1.5 wt% Liquid (Cetearyl Ethylhexanoate)

[0415] 0.6 wt% B 8832 (Bis-PEG / PPG-20 / 20 Polydimethylsiloxane)

[0416] 0.10 wt% Ceramide NP 15

[0417] B 0.3 wt% GMCY MB (Glyceryl Caprylate)

[0418] 0.5 wt% Cosmo C 250(1-methylhydantoin-2-imide)

[0419] 0.03 wt% (Sodium Hyaluronate)

[0420] 3.00 wt% glycerol

[0421] 3.00 wt% butanediol

[0422] 100 wt% demineralized water

[0423] 0.2 wt% Carbomer (Carbomer Homopolymer C)

[0424] 0.7 wt% HMB (Ammonium Acryloyldimethyltaurate, Behnenth-25 Methacrylate Crosspolymer)

[0425] C 1.00wt% Hexiol(1,2-Hexanediol)

[0426] Qs Sodium Hydroxide

[0427] 0.25 wt% Red 28 (0.02% in water)

[0428] D Sensitive NG (Water / Aqua; Glycerin; Lecithin; Dipotassium Glycyrrhizate; Calendula Officinalis Flower Extract; Lonicera Japonica Extract; Honeysuckle Flower Extract; Benzyl Alcohol; Benzoic Acid; Dehydroacetic Acid)

[0429] 20.14 Sunscreen SPF 15

[0430] A 3.00 wt% Care PBS 6MB (Polyglyceryl-6 Stearate (and) Polyglyceryl-6 Behenate)

[0431] 8.00 wt% XC MB (phenoxyethyl caprylate)

[0432] 5.00 wt% DEC (Diethylhexyl carbonate)

[0433] 3.00 wt% M Pellets MB (Glyceryl Stearate)

[0434] 2.00 wt% Alkanol 1618MB (cetearyl alcohol)

[0435] 1.00 wt% MM MB (Myristyl Myristate)

[0436] 0.50% by weight 350(Polydimethylsiloxane)

[0437] 0.50% by weight Feel C 10 (cellulose)

[0438] 2.50% by weight Diethylamino Hydroxybenzoyl Hexyl Benzoate

[0439] 6.00 wt% Homosalate

[0440] 0.50 wt% Tocopheryl acetate

[0441] 0.10 wt% Ceramide NP 15

[0442] B 11.58 wt% water

[0443] 0.42 wt% sodium hydroxide

[0444] 3.00 wt% Eusolex 232 (phenylbenzimidazole sulfonic acid)

[0445] C added to 100 wt% water

[0446] 3.00 wt% glycerol

[0447] 1.00 wt% Pep 4-17MB (Tetrapeptide-21; Glycerin; Butylene Glycol; Water)

[0448] 1.00 wt% Pep 4-Even MB (Tetrapeptide-30; Glycerin; Water)

[0449] 0.50% by weight Cosmo C 100 (creatine)

[0450] D 0.70 wt% Keltrol CG-SFT (xanthan gum)

[0451] E 1.10 wt% PC (phenoxyethanol; caprylyl glycol)

[0452] 0.50 wt% flavor

[0453] 20.15 UV Protection Hand Cream SPF20

[0454] A 1.50 wt% Care PBS 6MB (Polyglyceryl-6 Stearate (and) Polyglyceryl-6 Behenate)

[0455] 2.50 wt% TA 100 (Distearyl dimethyl ammonium chloride)

[0456] 2.00 wt% stearyl alcohol

[0457] 2.00 wt% M Pellets MB (Glyceryl Stearate)

[0458] 1.00 wt% SH MB (Stearyl Heptanoate)

[0459] 5.00 wt% TN(C12-15 Alkyl Benzoate)

[0460] 3.00 wt% Diethylamino Hydroxybenzoyl Hexyl Benzoate

[0461] 3.00 wt% Ethylhexyl salicylate

[0462] 5.00 wt% Ethylhexyl methoxycinnamate

[0463] 0.50 wt% Tocopheryl acetate

[0464] 0.10 wt% Ceramide NP 15

[0465] 0.05% Sterol KCS (Cholesterol Potassium Sulfate)

[0466] B added to 100 wt% water

[0467] 3.00 wt% glycerol

[0468] C 1.50 wt% Nylon-12

[0469] D 2.00 wt% Natural Betaine (Betaine)

[0470] 2.00 wt% (Sodium Lactate; Sodium PCA; Glycine; Fructose; Urea; Niacinamide; Inositol: Sodium Benzoate; Lactic Acid)

[0471] 2.00 wt% water

[0472] E qs preservatives

[0473] 0.50% by weight flavor "Azura 231517"

[0474] 20.16 Sunscreen SPF 30 with insect repellent activity

[0475] A 3.50 wt% Care PBS 6MB (Polyglyceryl-6 Stearate (and) Polyglyceryl-6 Behenate)

[0476] 2.00 wt% DC MB (Deca Cocoate)

[0477] 1.00 wt% TN(C12-15 Alkyl Benzoate)

[0478] 0.50% by weight PIB 1000 (Polyisobutylene)

[0479] 0.50% by weight M Pellets MB (Glyceryl Stearate)

[0480] 0.50 wt% stearyl alcohol

[0481] 15.00 wt% Insect repellent 3535 (ethyl butyl acetylaminopropionate)

[0482] 3.00 wt% Tinosorb S (bis-ethylhexyloxyphenol methoxyphenyl triazine)

[0483] 3.00 wt% Ethylhexyl salicylate

[0484] 6.00 wt% Homosalate

[0485] 8.00 wt% Octocrylene

[0486] 2.00 wt% Butyl Methoxydibenzoylmethane

[0487] 2.00 wt% Ethylhexyl methoxycinnamate

[0488] 0.10 wt% Ceramide NP 15

[0489] B added to 100 wt% water

[0490] 3.00 wt% glycerol

[0491] C 0.60 wt% Sepigel 305 (polyacrylamide (and) C13-14 isoparaffin (and) laureth-7)

[0492] D 0.70 wt% EUXYL PE 9010 (phenoxyethanol; ethylhexylglycerin)

[0493] Z qs flavor

[0494] 20.17 O / W Liquid Foundation for Even Skin Tone

[0495] A 4.00 wt% Care PBS 6MB (Polyglyceryl-6 Stearate (and) Polyglyceryl-6 Behenate)

[0496] 1.50 wt% Alkanol 1618MB (cetearyl alcohol)

[0497] 1.00 wt% M Pellets MB (Glyceryl Stearate)

[0498] 1.00 wt% MM MB (Myristyl Myristate)

[0499] 3.00 wt% TN(C12-15 Alkyl Benzoate)

[0500] 2.00 wt% DEC (Diethylhexyl carbonate)

[0501] 2.00 wt% 9045 Silicone Elastomer Blend (Cyclopentasiloxane (and) Dimethicone Crosspolymer)

[0502] 8.00 wt% Ethylhexyl methoxycinnamate

[0503] 5.00 wt% Ethylhexyl salicylate

[0504] 3.00 wt% Diethylamino Hydroxybenzoyl Hexyl Benzoate

[0505] 3.00 wt% Bis-ethylhexyloxyphenol methoxyphenyl triazine

[0506] (Bis-ethylhexyloxyphenol methoxyphenyl triazine)

[0507] 0.10 wt% Ceramide NP 15

[0508] B added to 100 wt% deionized water

[0509] 1.00 wt% glycerol

[0510] 0.15 wt% xanthan gum

[0511] C 8.00 wt% Titanium Dioxide; CI 77891

[0512] 1.70 wt% Covarine Yellow WN 1792GZ (CI 77492, water, glycerin, xanthan gum, sodium citrate)

[0513] 0.40 wt% Covarine Red WN 3798GZ (CI 77491, water, glycerin, xanthan gum, sodium citrate)

[0514] 0.10 wt% Covarine Black WN 9798GZ (CI 77499, water, glycerin, xanthan gum, sodium citrate)

[0515] 2.00 wt% glycerol

[0516] 3.00 wt% propylene glycol

[0517] D 2.00 wt% Nylon-12

[0518] E 2.00 wt% Q10NG (water; glycerin; lecithin; ubiquinone; tocopherol; benzyl alcohol; benzoic acid; dehydroacetic acid)

[0519] F 0.70 wt% Euxyl PE 9010 (phenoxyethanol, ethylhexylglycerin)

[0520] 20.18 Facial Mousse

[0521] A 2.50 wt% Care XL 80MB (Bis-PEG / PPG-20 / 5PEG / PPG-20 / 5 Dimethicone; Methoxy PEG / PPG-25 / 4 Dimethicone; Caprylic / Capric Triglyceride)

[0522] 5.00 wt% polydimethylsiloxane (5 mPas)

[0523] 4.00 wt% DEC (Diethylhexyl carbonate)

[0524] 3.00 wt% CT MB (Caprylic / Capric Triglyceride)

[0525] 1.00 wt% CR MB (Cetyl Ricinoleate)

[0526] 0.10 wt% Ceramide NP 15

[0527] 0.10 wt% Lift(Ceramide NP)

[0528] B 4.00 wt% Pep UP (Tetrapeptide-4; Glycerin)

[0529] 0.50% by weight Cosmo C 100 (creatine)

[0530] 0.50 wt% Panthenol

[0531] 0.20 wt% Allantoin

[0532] Add to 100 wt% water

[0533] C 1.60 wt% OS(Ethylhexyl Stearate)

[0534] 0.15 wt% Carbomer (Carbomer Homopolymer A)

[0535] 0.15 wt% Carbomer (Carbomer Homopolymer C)

[0536] 0.10 wt% Keltrol CG-SFT (xanthan gum)

[0537] D qs Sodium hydroxide (10% in water)

[0538] E 1.00 wt% Betain 810MB (Capryl / Caprylamidopropyl Betaine)

[0539] 1.00 wt% AM C MB (Sodium Cocoamphoacetate)

[0540] 0.70 wt% Euxyl PE 9010 (phenoxyethanol, ethylhexylglycerin)

[0541] Z qs flavor

[0542] 20.19 Mask

[0543] A 1.00 wt% PC 41MB (Polyglyceryl-4 Caprate)

[0544] 1.30 wt% Betain 810MB (Capryl / Capramidopropyl Betaine)

[0545] 1.00 wt% Solve 61MB (Polyglyceryl-6 Caprylate; Polyglyceryl-3 Cocoate; Polyglyceryl-4 Caprate; Polyglyceryl-6 Ricinoleate)

[0546] 1.00 wt% glycerol

[0547] 1.40 wt% hexanediol

[0548] 0.10 wt% Ceramide NP 15

[0549] B 0.50 wt% Carbomer 140

[0550] 2.00 wt% Natural Betaine (Betaine)

[0551] Add to 100 wt% water

[0552] 0.10 wt% xanthan gum

[0553] C 2.50 wt% Feel C 10 (cellulose)

[0554] 0.50% by weight Turmerone (Turmeric Root Extract)

[0555] 3.00 wt% BOB (Benzyl Alcohol, Caprylyl Glycol, Benzoic Acid)

[0556] qs wt% sodium hydroxide (10% in water)

[0557] D ACENG (glycerin, water, lecithin, tocopheryl acetate, 3-o-ethyl ascorbic acid, retinyl palmitate, tocopherol, benzyl alcohol, benzoic acid, dehydroacetic acid)

[0558] 20.20 Aftershave Cream

[0559] A 2.00 wt% C 62 Pellets MB (Citrate Glycerides)

[0560] 2.00 wt% M Pellets MB (Glyceryl Stearate)

[0561] 3.00 wt% Alkanol 1618MB (cetearyl alcohol)

[0562] 4.00 wt% DEC (Diethylhexyl carbonate)

[0563] 3.50 wt% DC MB (Deca Cocoate)

[0564] 2.00 wt% CR MB (Cetyl Ricinoleate)

[0565] 1.00 wt% OER MB (Oleyl Erucate)

[0566] 0.50% by weight MM MB (Myristyl Myristate)

[0567] 2.00 wt% Macadamia ternifolia seed oil

[0568] 0.50 wt% Tocopheryl acetate

[0569] 0.50 wt% Bisabolol

[0570] 0.50% by weight GMCY MB (Glyceryl Caprylate)

[0571] 0.10 wt% Ceramide NP 15

[0572] B added to 100 wt% water

[0573] 4.0 wt% glycerol

[0574] 0.50 wt% Panthenol

[0575] 0.20 wt% Allantoin

[0576] C 0.40 wt% Keltrol CG-SFT (xanthan gum)

[0577] D 7.00 wt% alcohol

[0578] E 0.01 wt% Natural citrus (citrus peel extract)

[0579] 0.02 wt% Natural Matricaria (Matricaria extract)

[0580] E 1.50 wt% SL non GMO (water; sodium levulinate; potassium sorbate)

[0581] 20.21 Skin Toner

[0582] A added to 100 wt% deionized water

[0583] 4.00 wt% Glycerol 99.5%, European Pharmacopoeia (Glycerol)

[0584] 0.20 wt% TEGO Natural Madecassoside (madecassoside)

[0585] 0.50 wt% Ajidew NL-50N (sodium PCA; water)

[0586] 0.10 wt% PA-3 (sodium phytate; water; alcohol)

[0587] B 1.50 wt% Solv Clearplus MB (caprylyl / decyl glucoside; water; sodium cocoyl glutamate; glyceryl caprylate; citric acid; polyglyceryl-6 oleate; sodium succinate)

[0588] 1.00 wt% decalact liquid MB (sodium caproyl / lauroyl lactylate; triethyl citrate)

[0589] 0.10 wt% Ceramide NP 15

[0590] 25.00 wt% Denatured ethanol (denatured alcohol)

[0591] 0.30 wt% flavor

[0592] 2.00 wt% TEC eco(Triethyl citrate)

[0593] 20.22 Shampoo and Body Wash

[0594] A 2.25 wt% One(Glycolipid)

[0595] 0.50% by weight sensolv MB (isoamyl laurate)

[0596] 9.70 wt% Lauryl Glucoside, 50%

[0597] 20.00 wt% Coco-Glucoside (50%)

[0598] 5.50% by weight Sodium Coco Sulfate, 91%

[0599] 0.10 wt% Ceramide NP 15

[0600] Add up to 100.00 wt% water

[0601] 6.80 wt% glycerol

[0602] 3.50 wt% 1388eco (glycerin, water, sodium levulinate, sodium anisate)

[0603] 1.05 wt% Remo 95MB (sorbitan caprate, glyceryl oleate)

[0604] Adjust pH with citric acid

[0605] 20.23 Micellar Water for Facial Cleansing

[0606] 2.00 wt% Solve 55MB (polyglyceryl-3 caprylate / caprate / succinate; propylene glycol)

[0607] 1.30 wt% Betain 810MB (Capryl / Caprylamidopropyl Betaine)

[0608] 0.10 wt% Ceramide NP 15

[0609] 0.05 wt% flavor

[0610] Add to 100.0 wt% water

[0611] 2.00 wt% Natural Betaine (Betaine)

[0612] 2.00 wt% TEGO Cosmo EPL (Polyepsilon Lysine Hydrochloride)

[0613] 1.40 wt% hexanediol

[0614] 1.00 wt% glycerol

[0615] QS preservatives

[0616] 20.24 No-rinse Dry Hair Conditioner

[0617] A 5.00 wt% Sulfosuccinate DO 75 (Sodium diethylhexyl sulfosuccinate)

[0618] 10.00 wt% sensolv MB (isoamyl laurate)

[0619] 48.00% by weight TN(C12-15 Alkyl Benzoate)

[0620] 30.00 wt% sunflower seed oil

[0621] 0.10 wt% Ceramide NP 15

[0622] B 5.00 wt% PC 31MB (Polyglyceryl-3 Caprate)

[0623] 1.00 wt% EQ 100 (Bis(isostearoyl / oleoyl isopropyl) dimethyl ammonium methosulfate)

[0624] 20.25W / O emulsion

[0625] A 2.5 wt% GPS (Polyglyceryl-4 diisostearate / polyhydroxystearate / sebacate)

[0626] 10.0 wt% DEC (Diethylhexyl carbonate)

[0627] 9.0 wt% OP(Ethylhexyl Palmitate)

[0628] 0.5 wt% zinc stearate

[0629] 0.10 wt% Ceramide NP 15

[0630] B added to 100.0 wt% water

[0631] 3.0 wt% glycerol

[0632] 1.5 wt% magnesium sulfate heptahydrate

[0633] Z qsPreservatives, flavors

[0634] 20.26 Natural Hair Oil for Thinning Hair

[0635] A 92.78 wt% sensolv MB (isoamyl laurate)

[0636] 1.00 wt% DC(Decyl Cocoate)

[0637] 1.00 wt% Argania spinosa kernel oil

[0638] 1.00 wt% Broccoli Seed Oil (Broccoli Seed Oil)

[0639] 0.5% weight% carrot juice; sesame seed oil (carrot oil

[0640] 1.00 wt% (Olea europaea (olive) fruit oil; Ricinus communis (castor seed oil; Ceramide NG))

[0641] 1.00 wt% coconut oil

[0642] 0.02% by weight sea buckthorn fruit oil

[0643] 0.50% by weight GMCY MB (Glyceryl Caprylate)

[0644] 0.20 wt% Toco 70 non GMO (tocopherol; sunflower seed oil)

[0645] 0.02 wt% Ceramide NP 15

[0646] 0.10 wt% Natural Coleus (Coleus forskohlii extract)

[0647] B 1.00 wt% flavor

[0648] 20.27 Waterless Hand Sanitizer – Solid Hand Cream for Improving Sustainability

[0649] A 45.80 wt% KahlJelly 7235MB Natural (Castor Seed Oil; Beeswax; Carnauba Wax; Sunflower Seed Oil; Tocopherol; Ascorbyl Palmitate)

[0650] 20.00 wt% KahlComplex 6422 Veggisoft (Rhus serrata peel wax; Simmondsia chinensis (Jojoba) seed oil; Cetearyl alcohol; Myristyl alcohol; Caprylic / capric triglyceride; Carnauba wax; Sunflower seed oil)

[0651] 10.00 wt% Kahlwax 2225 Phyto (Helianthus annuus (Sunflower Seed Wax; Olea europaea (Olive Oil); Sumac Wax; Shorea Robusta Resin)

[0652] 5.00 wt% Kahlwax 660 / H hydrolyzed sunflower seed wax (hydrolyzed sunflower seed wax)

[0653] 6.00 wt% OER MB (Oleyl Erucate)

[0654] 5.00 wt% DC MB (Deca Cocoate)

[0655] 2.00 wt% CR MB (Cetyl Ricinoleate)

[0656] 2.70 wt% Olea europaea (olive) fruit oil

[0657] 2.00 wt% Viscolid MB (Hydrogenated Palm Oil; Hydrogenated Rapeseed Oil)

[0658] 0.50% by weight GMCY MB (Glyceryl Caprylate)

[0659] 0.20 wt% TocoSkin (tocopherol; sunflower seed oil)

[0660] 0.20 wt% Toco 70 non GMO (tocopherol; Helianthus annuus (sunflower oil)

[0661] 0.10 wt% Ceramide NP 15

[0662] 0.50 wt% flavor

[0663] 20.28 Body Slimming Cream

[0664] A 43.20 wt% Kahlwax 6237 Rapeseed Oil (Hydrogenated Rapeseed Oil)

[0665] 8.90 wt% Kahlwax 6607L (sunflower seed wax; tocopherol; ascorbyl palmitate)

[0666] 3.00 wt% Kahlwax 2811 Rice (Oryza Sativa Bran Cera).

[0667] 12.50 wt% Prunus Amygdalus Dulcis (Sweet Almond) Oil

[0668] 11.50% by weight DC MB (Deca Cocoate)

[0669] 5.00 wt% OER MB (Oleyl Erucate)

[0670] 3.00 wt% CR MB (Cetyl Ricinoleate).

[0671] 2.00 wt% MM MB (Myristyl Myristate)

[0672] 2.00 wt% Viscolid MB (hydrogenated palm oil; hydrogenated rapeseed oil).

[0673] 1.30 wt% Argan oil

[0674] 5.00 wt% Persea Gratissima (Avocado) Oil

[0675] 0.50% by weight GMCY MB (Glyceryl Caprylate)

[0676] 0.20 wt% TocoSkin (tocopherol; sunflower seed oil)

[0677] 0.20 wt% Toco 70 non GMO (Tocopherol; Helianthus annuus (sunflower oil)).

[0678] 0.10 wt% Ceramide NP 15

[0679] 0.10 wt% Sterol KCS (Cholesterol Potassium Sulfate)

[0680] 1.00 wt% Covapate Uniwhite LC 9781 (Castor Seed Oil; CI 77891; Polyhydroxystearic Acid)

[0681] 0.50 wt% flavor

[0682] 20.29 Hair Care Shampoo Soap

[0683] A 45.90 wt% Pureact I-78, 80% (sodium cocoyl isethionate, 80%)

[0684] 2.50 wt% Feel C10(cellulose)

[0685] 0.30 wt% Jaguar C-162 (Hydroxypropyl Guar (and) Hydroxypropyl Guar Hydroxypropyltrimonium Chloride)

[0686] 30.40% by weight Oryza Sativa Starch (Resista Natural)

[0687] 8.00 wt% Betain 810MB (Capryl / Caprylamidopropyl Betaine)

[0688] 1.80 wt% ONE(Glycolipid)

[0689] 4.20 wt% LA-A (glycolipid; sodium lactate)

[0690] 1.00 wt% OER MB (Oleyl Erucate)

[0691] 3.00 wt% EQ 90 (Dioleoylethyl Hydroxyethyl Ammonium Methyl Sulfate)

[0692] 2.00 wt% Remo 95MB (sorbitan caprylate; glyceryl oleate)

[0693] 0.50% by weight GMCY (Glyceryl Caprylate)

[0694] 0.10 wt% Ceramide NP 15

[0695] 0.30 wt% flavor

[0696] 20.30 Sebum Skin Cleansing Foam

[0697] 6.00 wt% ONE(Glycolipid)

[0698] 11.00 wt% Betain 810MB (Capryl / Caprylamidopropyl Betaine)

[0699] 0.50% by weight Remo 95MB (sorbitan caprylate; glyceryl oleate)

[0700] 2.00 wt% decalact sebum MB (polyglyceryl-10 laurate; sodium caproyl / lauroyl lactylate; glycerin; saw palmetto fruit extract; juniper berry extract)

[0701] 4.00 wt% Pentiol eco(pentylene glycol)

[0702] 0.02 wt% Ceramide NP 15

[0703] 76.40% by weight Water (Aqua)

[0704] 20.31AP / Deodorant Spray

[0705] A 4.00 wt% 17MB (Polyglyceryl-4 Diisostearate / Polyhydroxystearate / Sebacate; Caprylic / Capric Triglyceride; Polyglyceryl-3 Oleate; Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate)

[0706] 0.25 wt% hydrogenated castor oil

[0707] 0.25 wt% microcrystalline wax

[0708] 20.50% by weight CT (Caprylic / Capric Triglyceride)

[0709] 10.00 wt% DEC (Diethylhexyl Carbonate)

[0710] 0.03 wt% Ceramide NP 15

[0711] B 31.97 wt% Water (Aqua)

[0712] 2.00 wt% glycerol

[0713] 30.00 wt% Locron LIC (aluminum chlorohydrate (50% aqueous solution))

[0714] C 1.00wt% Fragrance

[0715] 20.32 Deodorant Deodorant Stick

[0716] A 2.50 wt% dermofeel NC MB (polyglyceryl-3 distearate; glyceryl stearate citrate)

[0717] 20.00 wt% Alkanol 1618MB (cetearyl alcohol)

[0718] 2.00 wt% MM (Myristyl Myristate)

[0719] 10.00 wt% CR (Cetyl Ricinoleate)

[0720] 1.00 wt% PY 88G (zinc ricinoleate)

[0721] 10.00 wt% Viscolid MB (Hydrogenated Palm Oil; Hydrogenated Rapeseed Oil)

[0722] 33.70% by weight sunflower seed oil

[0723] 10.00 wt% OER MB (Oleyl Erucate)

[0724] 0.10 wt% Ceramide NP 15

[0725] 4.00 wt% 200(Silicon dioxide)

[0726] 6.00 wt% Feel C 10 (cellulose)

[0727] 0.30 wt% Cosmo P 813MB (Polyglyceryl-3 Caprylate)

[0728] 0.30 wt% 250eco(phenylpropanol)

[0729] B 0.10 wt% Bambus tetilis stem extract

[0730] 20.33 Deodorant Wipes

[0731] A 4.00 wt% A30eco (propylene glycol, zinc ricinoleate, water, arginine, citric acid)

[0732] 7.00 wt% Solve 90MB (Polyglyceryl-6 Caprylate; Polyglyceryl-4 Caprate)

[0733] 0.50% by weight Cosmo P 813MB (Polyglyceryl-3 Caprylate)

[0734] 0.25 wt% Texapon K12 G (sodium lauryl sulfate)

[0735] 0.05 wt% Ceramide NP 15

[0736] 1.20 wt% TBG (Triethyl Citrate, Caprylic Glyceryl, Benzoic Acid)

[0737] 0.30 wt% flavor

[0738] 2.00 wt% tec eco (triethyl citrate)

[0739] 0.30 wt% decalact MB (sodium caproyl / lauroyl lactylate; triethyl citrate; clary sage oil)

[0740] B 82.15 wt% Water (Aqua)

[0741] C 2.25 wt% citric acid, 20% solution in water

[0742] 20.34 Cationic Body Cream

[0743] A 4.50 wt% TA 100 (Distearyl dimethyl ammonium chloride)

[0744] 4.00 wt% stearyl alcohol

[0745] 3.00 wt% M Pellets MB (Glyceryl Stearate)

[0746] 5.00 wt% CT MB (Caprylic / Capric Triglyceride)

[0747] 5.00 wt% AC MB (Isoamyl Cocoate)

[0748] 5.00 wt% SH(Stearyl Heptanoate)

[0749] 0.50% by weight 350(Polydimethylsiloxane)

[0750] 0.10 wt% Ceramide NP 15

[0751] B 64.20 wt% Water (Aqua)

[0752] 5.00 wt% glycerol

[0753] C 2.00 wt% ProContour (water, alcohol, lecithin, caffeine, carnitine, Centella asiatica leaf extract, potassium phosphate, Coleus Barbatus root extract, tocopherol)

[0754] D 1.00 wt% Verstatil PC (phenoxyethanol; caprylyl glycol)

[0755] 20.35 Hand Cream

[0756] A 2.00 wt% C Pellets MB (Ceteareth-25

[0757] 3.50 wt% M Pellets MB (Glyceryl Stearate)

[0758] 2.00 wt% Alkanol 1618MB (cetearyl alcohol)

[0759] 7.50 wt% Isopropyl myristate

[0760] 2.00 wt% DC(Decyl Cocoate)

[0761] 1.00 wt% 350(Polydimethylsiloxane)

[0762] 2.00 wt% Wax 9840 (Cetyl Dimethicone)

[0763] 1.50 wt% white beeswax

[0764] 0.08 wt% Ceramide NP

[0765] B 3.00 wt% glycerol

[0766] 0.50 wt% Panthenol

[0767] 71.90% by weight water (Aqua)

[0768] C 2.00 wt% TEGO enlight (Mulberry fruit extract; sodium phytate; water; glycerin; alcohol)

[0769] C 1.00 wt% Euxyl PE 9010 (phenoxyethanol; ethylhexylglycerin)

[0770] 20.36 Refreshing Foot Cream

[0771] A 6.00 wt% Pellets MB (Glyceryl Stearate SE)

[0772] 2.00 wt% Alkanol 1618MB (cetearyl alcohol)

[0773] 1.00 wt% stearic acid

[0774] 1.00 wt% 350(Polydimethylsiloxane)

[0775] 5.00 wt% CT MB (Caprylic / Capric Triglyceride)

[0776] 5.00 wt% OS(Ethylhexyl Stearate)

[0777] 4.00 wt% mineral oil

[0778] 1.00 wt% TEGO Natural Amaranth (Amaranth Seed Extract)

[0779] 0.10 wt% Ceramide NP

[0780] B 7.00 wt% glycerol

[0781] 64.40% by weight Water (Aqua)

[0782] 3.00 wt% Sorbitol

[0783] C 0.50wt%SK- V MB (ceramide NP; ceramide AP; ceramide EOP; phytosphingosine; cholesterol; sodium lauroyl lactylate; carbomer; xanthan gum)

[0784] D PC (phenoxyethanol; caprylyl glycol)

[0785] 20.37 Anti-wrinkle Eye Cream

[0786] A 3.00 wt% TEGO Care 450MB (Polyglyceryl-3 Methylglucose Distearate)

[0787] 1.50 wt% TEGIN M Pellets MB (glyceryl stearate)

[0788] 1.50 wt% TEGO Alkanol 1618MB (cetearyl alcohol)

[0789] 2.00 wt% TEGOSOFT CT MB (caprylic / capric triglyceride)

[0790] 4.00 wt% TEGOSOFT OP MB (ethylhexyl palmitate)

[0791] 9.50 wt% TEGOSOFT DC MB (decyl cocoate)

[0792] 4.00 wt% Prunus Amygdalus Dulcis (Sweet Almond) Oil

[0793] 0.10 wt% Ceramide NP 15

[0794] 0.35 wt% dermosoft GMCY MB (Glyceryl Caprylate)

[0795] B 65.35 wt% Water (Aqua)

[0796] 3.00 wt% glycerol

[0797] C 0.20 wt% Keltrol CG-SFT (xanthan gum)

[0798] D 2.00 wt% TEGO Pep 4-17MB (Tetrapeptide-21; Glycerin; Butylene Glycol; Water)

[0799] E 2.00 wt% ROVISOMEFEC (water; alcohol; lecithin; aescin; Ascophyllum nodosum extract; caffeine; potassium phosphate; tocopherol)

[0800] F 1.50 wt% Verstatil SL non GMO (water; sodium levulinate; potassium sorbate)

Claims

1. A composition comprising A) at least one self-tanning agent B) at least one sphingolipid of the general formula I in R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H, X is CH=CH, CH2-CH2 or CH2-HCOH, preferably CH2-HCOH, and n is an integer selected from 3 to 8, preferably 6 to 7, most preferably 6, and / or at least one A sphingoid base selected from the group consisting of N-acetylphytosphingosine, phytosphingosine, sphingosine and dihydrosphingosine.

2. The composition according to claim 1, characterized in that The at least one self-tanning agent is selected from dihydroxyacetone and erythrulose.

3. The composition according to claim 1 or 2, characterized in that The sphingolipids of formula I are selected from those wherein R 1 It is H. X is CH2-HCOH, and n is an integer selected from 6 to 7, most preferably 6.

4. A composition according to any one of the preceding claims, characterized in that A) is contained in an amount of 0.02 to 1.50 wt %, preferably 0.03 to 1.00 wt %, more preferably 0.05 to 0.50 wt %, the weight percentages being based on the total composition.

5. A composition according to any one of the preceding claims, characterized in that B) is contained in an amount of 0.5 to 15.0 wt %, preferably 1.0 to 10.0 wt %, more preferably 3.0 to 6.0 wt %, the weight percentages being based on the total composition.

6. The composition according to any one of the preceding claims, which is a cosmetic preparation.

7. The composition according to claim 6, further comprising At least one UV protection filter substance.

8. The sphingolipid of formula Ib in R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H, X is CH2-HCOH, and n 6， or among them R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H, X is CH=CH or CH2-HCOH, preferably CH2-HCOH, and n 5。 9. Use of the sphingolipid according to claim 8 as a medicine.

10. Use of the sphingolipid of claim 8 for treating acne, atopic dermatitis, psoriasis, herpes, warts, rosacea, skin cancer, pemphigus, alopecia, epidermolysis bullosa, scleroderma, ichthyosis, vitiligo and / or Raynaud's phenomenon.

11. A composition, preferably a cosmetic preparation, comprising a sphingolipid of the general formula Ib according to claim 8.

12. Use of at least one sphingolipid of the general formula I and / or at least one sphingoid base selected from N-acetylphytosphingosine, phytosphingosine, sphingosine and dihydrosphingosine for enhancing the self-tanning effect of a self-tanning agent, in R 1 is H, phosphorylcholine, serine, ethanolamine or sugar, preferably sugar or H, more preferably H, X is CH=CH, CH2-CH2 or CH2-HCOH, preferably CH2-HCOH, and n is an integer selected from 3 to 8, preferably 6 to 7, most preferably 6.

13. Cosmetic use of at least one composition according to any one of claims 1 to 7 and 11 for tanning human skin.

Images