Multifunctional full-automatic solid target dissolving device

Abstract

The invention provides a multifunctional full-automatic solid target dissolving device. The multifunctional full-automatic solid target dissolving device comprises a cabinet body, an operation platform positioned above the cabinet body and an equipment mounting table adjacent to the operation platform, a rabbit pre-placing station, a rabbit receiving and dispatching port, a dissolving station and a reagent bottle seat are arranged on the operating platform; the dissolving station comprises a heating device mounted in the cabinet body; a sliding rail is arranged at the top of the equipment mounting table, a receiving and sending device is mounted on the sliding rail, a grabbing mechanism is mounted at the bottom of the receiving and sending device, a lifting air cylinder is further mounted on the sliding rail, a dissolving tank matched with the dissolving station is mounted below the lifting air cylinder, and a plurality of pipeline connecting ports are formed in the top of the dissolving tank; and a peristaltic pump is further mounted in the equipment mounting table. The multifunctional full-automatic solid target dissolving device is suitable for automatic operation of solid target material dissolving, dissolving and transmission after dissolving are carried out in a closed environment, and the efficiency and safety of the target material dissolving process are improved.

Description

Technical Field

[0001] The invention belongs to the field of radionuclide manufacturing, and in particular relates to a multifunctional fully automatic solid target dissolving device. Background Art

[0002] Cyclotron is one of the important ways to produce radionuclides. The principle is to generate high-speed charged particles through the accelerator to bombard the selected stable elements on the target, thereby inducing nuclear reactions to produce radionuclides for nuclear medicine diagnosis and treatment, industry and agriculture. Commonly used radionuclides include 18F, 64Cu, 67Ga, 89Zr, 123I, etc. These radionuclides have a wide range of applications in the medical field, such as diagnosis and treatment of cancer.

[0003] The target is the core component for producing radioactive nuclides. According to its different forms, it can be divided into three types: solid target, liquid target and gas target. Among them, the solid target is the most commonly used form for producing radioactive nuclides. After the solid target completes the nuclear reaction in the accelerator, the target nuclides need to be produced on the target. The target nuclides on the target need to be dissolved and separated and purified to remove impurities, and finally obtain a target nuclide product with higher purity. Since the chemical properties of most target products are not active, they usually need to be heated and properly stirred to achieve complete dissolution.

[0004] Traditional solid target dissolution methods are usually performed manually in a relatively open environment, which has many limitations: first, manual operation requires operators to be exposed to radioactive materials for a long time, increasing the risk of radiation; second, the open operating environment easily leads to the leakage of waste gas and waste liquid, causing environmental pollution. In addition, the dissolution efficiency of manual operation is relatively low, and the waste gas generated during the dissolution process is difficult to effectively collect and treat. Summary of the invention

[0005] In order to overcome the defects of the prior art, the present invention discloses a multifunctional fully automatic solid target dissolving device.

[0006] The multifunctional fully automatic solid target dissolution device of the present invention comprises a cabinet, an operating platform located above the cabinet, and an equipment installation platform adjacent to the operating platform; the operating platform is provided with a rabbit pre-placement station, a rabbit transceiver, a dissolution station, and a reagent bottle holder; the rabbit transceiver is connected to a rabbit accommodating cavity arranged inside the cabinet; the dissolution station comprises a heating device installed in the cabinet; A slide rail is provided on the top of the equipment mounting platform, a transceiver is installed on the slide rail, a grabbing mechanism is installed at the bottom of the transceiver, a lifting cylinder is also installed on the slide rail, a dissolving tank cooperating with the dissolving station is installed below the lifting cylinder, a plurality of pipe connection ports are provided on the top of the dissolving tank, and a peristaltic pump is also installed in the equipment mounting platform.

[0007] Preferably, the gripping mechanism is a negative pressure suction cup.

[0008] Preferably, the multifunctional fully automatic solid target dissolution device further comprises an air pump installed in the cabinet.

[0009] Preferably, a stirring device is installed on the top of the dissolving tank.

[0010] Preferably, a waste target accommodating chamber is provided inside the cabinet, and the waste target accommodating chamber is connected to a waste target collecting port on the operating platform.

[0011] Preferably, the dissolving tank is a sealed container with an opening at the lower end, and the dissolving station has an annular groove corresponding to the shape of the opening of the dissolving tank.

[0012] The multifunctional fully automatic solid target dissolving device of the present invention is suitable for the automated operation of solid target material dissolution. The dissolution and the transmission after dissolution are carried out in a closed environment, thereby improving the efficiency and safety of the target material dissolution process. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 This is a schematic diagram of a specific embodiment of the multifunctional fully automatic solid target dissolution device of the present invention; The names of the reference numerals in the figure are: 1. cabinet; 2. operating platform; 3. equipment installation table; 4. rabbit pre-placement station; 5. rabbit sending and receiving port; 6. dissolution station; 7. reagent bottle holder; 8. sending and receiving device; 9. lifting cylinder; 10. dissolution tank; 11. peristaltic pump; 12. waste target collection port. DETAILED DESCRIPTION

[0014] The specific implementation modes of the present invention are further described in detail below.

[0015] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely explained below in combination with the specific implementation methods of the present invention and the corresponding drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0016] like Figure 1 As shown, the multifunctional fully automatic solid target dissolution device of the present invention comprises a cabinet 1, an operating platform 2 located above the cabinet, and an equipment installation platform 3 adjacent to the operating platform; the operating platform is provided with a rabbit pre-placement station 4, a rabbit transceiver port 5, a dissolution station 6 and a reagent bottle seat 7; the rabbit transceiver port 5 is connected to a rabbit accommodating cavity arranged inside the cabinet; the dissolution station comprises a heating device installed in the cabinet; A slide rail is provided on the top of the equipment installation platform, a transceiver device 8 is installed on the slide rail, a grabbing mechanism is installed at the bottom of the transceiver device, a lifting cylinder 9 is also installed on the slide rail, a dissolving tank 10 cooperating with the dissolving station is installed below the lifting cylinder, a plurality of pipe connection ports are provided on the top of the dissolving tank, and a peristaltic pump 11 is also installed in the equipment installation platform.

[0017] The reagent bottle holder can generally accommodate multiple reagent bottles, such as Figure 1 As shown, there are two groups of reagent bottle holders 7, each group can accommodate two reagent bottles, each of which can accommodate different reagents. When in use, the pipe connecting port on the reagent bottle cap is connected to the pipe connecting port on the top of the dissolution tank; when the multifunctional fully automatic solid target dissolution device is used, an air pump is required as the sample conveying power. An external air pump can be used, or the air pump can be installed inside the cabinet and connected to the pipe connecting port on the top of the dissolution tank through a pipe.

[0018] When in use, first connect the reagent bottles to be used to the pipe connection port on the top of the dissolution tank 10 through the pipe, and the air pump and the peristaltic pump 11 are also connected to the pipe connection port on the top of the dissolution tank 10 through the pipe and the switchable pipe joint, and the pipe joints on the unused pipe connection ports are all sealed; then the solid target piece that has completed the target shooting is placed in the rabbit pre-placement station through the rabbit running device; the rabbit running device refers to a device that is driven by air pressure or hydraulic pressure to transport the small container containing the irradiated sample through the pipe in a sealed manner. The transported sample is called a rabbit or rabbit.

[0019] The transceiver 8 grabs the solid target piece through the grabbing structure. The grabbing mechanism can use a negative pressure suction cup. After the transceiver grabs the target piece, it moves horizontally on the slide rail to above the running rabbit receiving and sending port 5, and temporarily stores the target piece in the running rabbit accommodating cavity inside the cabinet.

[0020] Since waste targets may appear during the shooting process, a waste target accommodating chamber can be provided inside the cabinet 1, the waste target accommodating chamber is connected to the waste target collecting port 12 on the operating platform 2, and the transceiver places the waste targets in the waste target accommodating chamber.

[0021] When the dissolving operation is required, the transceiver will grab the target piece temporarily stored in the rabbit holding cavity and place it in the dissolving station. Then the lifting cylinder 9 moves on the slide rail to align the corresponding dissolving tank 10 with the dissolving station 6 and control the dissolving tank 10 to descend. The dissolving tank is a sealed container with an opening at the lower end. The dissolving station has an annular groove corresponding to the shape of the opening of the dissolving tank. After the dissolving tank descends, it is inserted into the annular groove to form a sealed space with the target piece together with the dissolving station.

[0022] Then, the air pump is turned on, and the reagent in the reagent bottle connected to the dissolving tank is sucked into the dissolving tank by vacuuming the inside of the dissolving tank 10. After the air pump is turned off, the heating device of the dissolving station in the dissolving tank can be turned on to heat the dissolving reaction, clean and other operations. The heating device is usually an electric heating wire. In a preferred embodiment, a stirring device can be installed on the top of the dissolving tank. After the dissolving tank and the dissolving station form a sealed space and the reagent is sucked in, turning on the stirring device can accelerate the dissolution.

[0023] During the dissolution process, when new reagents need to be added, the pipe joint used to connect the reagent bottle to the dissolution tank 10 is closed, and the joint connected to the new reagent bottle is opened. After the dissolution is completed, the peristaltic pump is turned on to suck the liquid in the dissolution tank out to the purification device connected to the peristaltic pump 11 for the next purification operation.

[0024] Specific embodiment: a target piece for dissolving copper element Cu (64); A 3mm silicone hose is used to connect the reagent bottle, peristaltic pump and dissolution tank, and a 2mm polytetrafluoroethylene (PTFE) tube is used to connect the reagent bottle and the dissolution tank through an inverted cone joint. The connection between the polytetrafluoroethylene tube and the silicone hose can be achieved by extrusion so that the polytetrafluoroethylene tube is directly embedded in the silicone hose connection.

[0025] The target piece containing the copper element Cu(64) has been pre-placed in the holding cavity of the running rabbit. The transceiver grabs the target piece through the grabbing structure and places it in the dissolution station. The dissolution tank is lowered and closed to form a closed space. Then the air pump is turned on to vacuum and 2ml of 6M (mol / L) HCl is drawn from the reagent bottle. The air pump is turned off and the dissolution tank is heated to 140 degrees Celsius for 1.5 hours of dissolution. The dissolved liquid is transferred to the nuclide bottle of the purification module by a peristaltic pump. Then 2ml of 6M HCl is injected to clean the dissolution tank, and the cleaning liquid is transferred to the nuclide bottle of the purification module by a peristaltic pump. Finally, the reagent bottle is switched, and 5ml of water is sucked into the dissolution tank by an air pump to clean the pipeline and dissolution tank, and then transferred to the waste liquid bottle of the purification device.

[0026] The multifunctional fully automatic solid target dissolving device of the present invention is suitable for the automated operation of solid target material dissolution. The dissolution and the transmission after dissolution are carried out in a closed environment, thereby improving the efficiency and safety of the target material dissolution process.

[0027] The foregoing describes various preferred embodiments of the present invention. Unless the preferred implementation modes in various preferred embodiments are obviously self-contradictory or based on a certain preferred implementation mode, various preferred implementation modes can be arbitrarily superimposed and used in combination. The embodiments and specific parameters in the embodiments are only for clearly describing the invention verification process of the inventor, and are not used to limit the patent protection scope of the present invention. The patent protection scope of the present invention shall still be based on its claims. All equivalent structural changes made using the contents of the description and drawings of the present invention should be included in the protection scope of the present invention.

Claims

1. A multifunctional fully automatic solid target dissolution device, characterized in that: The invention comprises a cabinet (1), an operating platform (2) located above the cabinet, and an equipment installation platform (3) adjacent to the operating platform; the operating platform is provided with a rabbit pre-placement station (4), a rabbit transceiver (5), a dissolution station (6), and a reagent bottle holder (7); the rabbit transceiver (5) is connected to a rabbit accommodating cavity arranged inside the cabinet (1); the dissolution station (6) comprises a heating device installed inside the cabinet (1); A slide rail is provided on the top of the equipment installation platform, a transceiver (8) is installed on the slide rail, a gripping mechanism is installed at the bottom of the transceiver, a lifting cylinder (9) is also installed on the slide rail, a dissolving tank (10) cooperating with the dissolving station is installed below the lifting cylinder (9), the top of the dissolving tank (10) has a plurality of pipe connection ports, and a peristaltic pump (11) is also installed in the equipment installation platform.

2. The multifunctional fully automatic solid target dissolution device according to claim 1, characterized in that: The grabbing mechanism is a negative pressure suction cup.

3. The multifunctional fully automatic solid target dissolution device according to claim 1, characterized in that: The multifunctional fully automatic solid target dissolving device also includes an air pump installed in the cabinet.

4. The multifunctional fully automatic solid target dissolution device according to claim 1, characterized in that: A stirring device is installed on the top of the dissolving tank (10).

5. The multifunctional fully automatic solid target dissolution device according to claim 1, characterized in that: A waste target accommodating chamber is provided inside the cabinet (1), and the waste target accommodating chamber is connected to a waste target collecting port (12) on the operating platform (2).

6. The multifunctional fully automatic solid target dissolution device according to claim 1, characterized in that: The dissolving tank (10) is a sealed container with an opening at the lower end, and the dissolving station (6) has an annular groove corresponding to the shape of the opening of the dissolving tank.

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