Novel uniform mixing device for suspended substances
By designing a mixing device of a new type of suspended substance including a spray mixing assembly and a heat dissipation assembly, the problem of inconsistent experimental results caused by the settlement of microspheres in the liquid medium is solved, and better mixing effect and convenience of use are achieved.
Patent Information
- Application Number
- CN202411843887.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-13
- Publication Date
- 2025-03-28
AI Technical Summary
The settlement of microspheres in liquid media leads to changes in concentration, distortion of standard curves, deviations in analysis and detection data, fluctuations in signal intensity, and decreasing cell capture efficiency.
A new type of mixed device for suspended substances is designed, including an outer shell and an inner shell. The inner shell is equipped with a liquid suction port and a liquid outlet port. The installation chamber is equipped with a spray mixing component and a heat dissipation component. The suspension substance is continuously pumped and sprayed and flowed through the spray mixing component to avoid settlement.
It effectively avoids the uneven sample addition problem caused by the settlement of suspended substances in the liquid, improves the mixing effect, is convenient to use, and solves the problem that it is difficult to ensure the mixing effect of microspheres in the prior art.
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Figure CN119701698A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the fields of biomedicine, biotechnology and laboratory technology, and in particular to a novel mixing device for suspended substances. Background Art
[0002] At present, microspheres are widely used in many fields such as biomedicine, chemical analysis, and environmental monitoring as important scientific research tools and industrial raw materials. Microspheres usually refer to particles with diameters ranging from nanometers to millimeters. They can be divided into polymer microspheres, silica microspheres, metal oxide microspheres, etc. according to their materials. Microspheres are also called resin products because of their unique physical and chemical properties. They have important applications in in vitro diagnostics (IVD), drug delivery systems, cell separation, and chemical synthesis catalysts.
[0003] However, microsphere sedimentation is a problem that may be encountered when using microspheres in liquid media, especially during long periods of operation or static conditions. This phenomenon can have a variety of effects on experimental results, such as:
[0004] Concentration variation: If your experiment relies on a uniformly distributed concentration of microspheres, sedimentation can cause differences in microsphere concentration at different locations or time points, affecting the consistency of your experimental results.
[0005] Standard curve distortion: In experiments that require the establishment of a standard curve (such as quantitative analysis using fluorescent microspheres), if the microspheres settle, the slope and intercept of the standard curve may change, thereby affecting the accuracy of the results.
[0006] Analysis and detection data bias: For experiments that require precise measurement of microsphere number or distribution (such as flow cytometry), microsphere sedimentation can lead to data bias because the distribution of microspheres after sedimentation no longer represents the state of the original sample.
[0007] Signal intensity fluctuations: If the microspheres are fluorescently or otherwise labeled, sedimentation may result in changes in the detection signal, thus affecting the final analytical results.
[0008] Cell capture efficiency: In cell capture or separation experiments, if the microspheres used settle, the cell capture efficiency may decrease, affecting subsequent cell processing and analysis.
[0009] At present, in order to reduce or avoid the impact of microsphere sedimentation on the experiment, the following measures can be taken:
[0010] Stirring or shaking: Keep the microspheres suspended by continuous stirring or shaking. Replace the microspheres: Use microspheres with a density close to the experimental medium, or choose microspheres with stabilizers to slow down the sedimentation rate. Short-time operation: Try to shorten the experimental operation time to reduce the possibility of sedimentation. However, these effects are limited and still cannot guarantee the mixing effect of the microspheres well, or they are difficult to implement. Summary of the invention
[0011] In order to solve one or some technical problems existing in the prior art, the purpose of the present application is to provide a new type of mixing device for suspended substances, so as to avoid the problem of uneven sample addition caused by the sedimentation of suspended substances in liquid and improve the mixing effect.
[0012] In order to solve the above existing technical problems, one of the purposes of this application is achieved by adopting the following technical solution:
[0013] A novel mixing device for suspended matter, comprising an outer shell, an inner shell arranged on the inner side of the outer shell, the inner shell being used to place the suspended matter, the top of the outer shell being fixedly connected to the top of the inner shell by a connecting plate, the outer shell and the inner shell mutually enclose a mounting cavity, the bottom of the inner shell is provided with a liquid suction port, the bottom of the inner shell is also provided with ten liquid outlets, a pumping and spraying mixing component is provided in the mounting cavity, the inlet of the pumping and spraying mixing component is connected with the liquid suction port, the outlet of the pumping and spraying mixing component is connected with the ten liquid outlets, the pumping and spraying mixing component can suck the suspended matter from the liquid suction port and spray it from the liquid outlet, the mixing device achieves mixing after pumping and spraying the suspended matter through the pumping and spraying mixing component; a heat dissipation component is also provided in the mounting cavity, the heat dissipation component plays a role of heat dissipation for the pumping and spraying mixing component, the heat dissipation component comprises an air outlet provided on the rear side wall of the outer shell, an installation window provided on the front side wall of the outer shell, and a fan provided on the inner side wall of the outer shell.
[0014] Furthermore, the pumping, spraying and mixing component includes a pump body fixedly arranged at the bottom of the installation cavity, a suction tube sealed between the suction port and the liquid inlet of the pump body, a liquid outlet hard pipe connected to the pump body outlet, and a liquid outlet hose sealed and connected to the liquid spray port, and the other end of the liquid outlet hose is connected to the liquid outlet hard pipe.
[0015] Furthermore, a mesh plate is hinged at the bottom of the installation window, a filter plate is detachably provided on the mesh plate, and a limiting component is arranged on the front side wall of the shell and limits the mesh plate.
[0016] Furthermore, two L-shaped clamping plates are symmetrically arranged on the rear side wall of the mesh plate, and the filter plate is clamped between the two L-shaped clamping plates.
[0017] Furthermore, the limiting assembly includes a shell fixedly arranged on the front side wall of the shell, a slot opened on the front side wall of the mesh plate, an insertion rod penetrating between the shell and the shell and capable of being inserted into the slot, a blocking rod located in the shell and fixedly connected to the insertion rod, and a limiting spring arranged between the blocking rod and the inner side wall of the shell and sleeved on the insertion rod.
[0018] Compared with the prior art, the present invention has the following beneficial effects:
[0019] (1) When in use, a suspended substance is placed in the inner shell, and then the pumping and spraying mixing component is started, so that the pumping and spraying mixing component continuously pumps and sprays the liquid suspended substance at a high speed, and continuous mixing can be performed when the microspheres are stationary to avoid the influence of sedimentation, thereby avoiding the problem of uneven sample addition caused by the sedimentation of the suspended substance in the liquid, improving the mixing effect, and being easy to use. Compared with the existing technology, it solves the technical problem that the mixing effect of the microspheres cannot be well guaranteed or is difficult to implement. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 This is a schematic diagram of the overall structure of the present application, showing a schematic diagram of the structure of the pumping, spraying and mixing component;
[0021] Figure 2 It is a schematic diagram of the structure of the limit assembly in this application;
[0022] Figure 3 It is a schematic diagram of the structure of the heat dissipation component in this application;
[0023] Figure 4 This is a schematic diagram of the structure of the mesh board in this application;
[0024] Figure 5 This is a schematic diagram of the structure in which the filter plate is inserted between two L-shaped card plates in this application;
[0025] In the figure: 1. inner shell; 2. outer shell; 3. connecting plate; 4. suction port; 5. spray port; 6. air outlet; 7. limit assembly; 8. pump body; 9. liquid outlet pipe; 10. liquid outlet hose; 11. fan; 12. installation window; 13. mesh plate; 14. L-shaped card plate; 15. shell; 16. plug rod; 17. slot; 18. stop rod; 19. limit spring; 20. filter plate; 21. suction and spray mixing assembly; 22. installation cavity; 23. suction pipe; 24. heat dissipation assembly. DETAILED DESCRIPTION
[0026] Below, the present application is further described in conjunction with the accompanying drawings and specific implementation methods. It should be noted that, under the premise of no conflict, the various embodiments or technical features described below can be arbitrarily combined to form a new embodiment.
[0027] In the description of the present application, it should be understood that the terms "up", "down", "left", "right", etc., indicating directions or positional relationships are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as a limitation on the present application.
[0028] The terms "first", "second", etc. in this application are used to distinguish similar objects, and are not used to describe a specific order or sequence. It should be understood that the data used in this way can be interchanged where appropriate, so that the embodiments of the present application can be implemented in an order other than those illustrated or described herein, and the objects distinguished by "first", "second", etc. are generally of one type, and the number of objects is not limited. For example, the first object can be one or more. In addition, "and / or" in the specification and claims represents at least one of the connected objects, and the character " / " generally indicates that the objects before and after are in an "or" relationship of a new type of mixing device for suspended substances.
[0029] Embodiment 1:
[0030] like Figure 1-Figure 5 As shown, the present embodiment provides a novel mixing device for suspended matter, which includes an outer shell 2 and an inner shell 1 arranged on the inner side of the outer shell 2, the inner shell 1 is used to place suspended matter, the top of the outer shell 2 is fixedly connected to the top of the inner shell 1 by a connecting plate 3, the outer shell 2 and the inner shell 1 mutually enclose a mounting cavity 22, a liquid suction port 4 is provided at the bottom of the inner shell 1, and ten liquid outlets are also provided at the bottom of the inner shell 1, a pumping and spraying mixing component 21 is provided in the mounting cavity 22, the inlet of the pumping and spraying mixing component 21 is connected to the liquid suction port 4, and the outlet of the pumping and spraying mixing component 21 is connected to the ten liquid outlets, the pumping and spraying mixing component 21 can suck the suspended matter from the liquid suction port 4 and spray it out from the liquid outlet, and the mixing device achieves mixing after the suspended matter is pumped and sprayed by the pumping and spraying mixing component 21.
[0031] A novel mixing device for suspended matter comprises an outer shell 2, an inner shell 1 is arranged inside the outer shell 2, and the inner shell 1 is used to place the suspended matter. The top of the outer shell 2 is fixedly connected to the top of the inner shell 1 by a connecting plate 3, so that the outer shell 2 and the inner shell 1 are mutually enclosed to form an installation cavity 22, a liquid suction port 4 is opened at the bottom of the inner shell 1, and ten liquid outlets are also opened at the bottom of the inner shell 1, and a pumping and spraying mixing component 21 is arranged in the installation cavity 22, so that the inlet of the pumping and spraying mixing component 21 is connected with the liquid suction port 4, and the outlet of the pumping and spraying mixing component 21 is connected with the ten liquid outlets. The pumping and spraying mixing component 21 can suck the suspended matter from the liquid suction port 4 and spray it out from the liquid outlet, and the mixing device realizes mixing after the suspended matter is pumped and sprayed by the pumping and spraying mixing component 21. When in use, a suspended substance is placed in the inner shell 1, and then the pumping and spraying mixing component 21 is started, so that the pumping and spraying mixing component 21 continuously pumps and sprays the liquid suspended substance at a high speed, and can be continuously mixed when the microspheres are stationary to avoid the influence of sedimentation, thereby avoiding the problem of uneven sample addition caused by the sedimentation of the suspended substance in the liquid, improving the mixing effect, and being easy to use. Compared with the existing technology, it solves the technical problems that the mixing effect of the microspheres cannot be well guaranteed or the implementation is difficult.
[0032] Furthermore, the suction-spraying and mixing component 21 includes a pump body 8 fixedly arranged at the bottom of the installation cavity 22, a suction pipe 23 sealed between the suction port 4 and the liquid inlet of the pump body 8, a liquid outlet hard pipe 9 connected to the outlet of the pump body 8, and a liquid outlet hose 10 sealed and connected to the liquid spraying port 5, and the other end of the liquid outlet hose 10 is connected to the liquid outlet hard pipe 9.
[0033] The pumping, spraying and mixing component 21 includes a pump body 8 fixedly arranged at the bottom of the installation cavity 22, a liquid suction pipe 23 is sealedly connected between the liquid suction port 4 and the liquid inlet of the pump body 8, a liquid outlet hard pipe 9 is connected to the outlet of the pump body 8, and a liquid outlet hose 10 is sealed and connected at the liquid spraying port 5, so that the other ends of the ten liquid outlet hoses 10 are all connected to the liquid outlet hard pipe 9. When in use, the pump body 8 is started to spray the liquid suspended matter through the liquid suction pipe 23, the liquid outlet hard pipe 9, and the ten liquid outlet hoses 10, so that the liquid suspended matter continues to flow at a high speed by pumping and spraying, and can be continuously mixed when the microspheres are stationary.
[0034] Furthermore, a heat dissipation component 24 is also provided in the installation cavity 22, and the heat dissipation component 24 plays a role in dissipating heat for the suction and spray mixing component 21. The heat dissipation component 24 includes an air outlet 6 opened on the rear side wall of the outer shell 2, an installation window 12 opened on the front side wall of the outer shell 2, and a fan 11 arranged on the inner wall of the outer shell 2.
[0035] When this technical solution is not provided, the following problems are likely to occur: the pump body 8 on the heat dissipation component 24 will generate heat when working, and if the heat cannot be dissipated well, the service life of the pump body 8 will be affected.
[0036] A heat dissipation component 24 is also provided in the installation cavity 22, and the heat dissipation component 24 plays a role in heat dissipation for the pumping, spraying and mixing component 21. The heat dissipation component 24 includes an air outlet 6 provided on the rear side wall of the shell 2, an installation window 12 provided on the front side wall of the shell 2, and a fan 11 provided on the inner side wall of the shell 2. When in use, the fan 11 is started, and the fan 11 circulates the wind between the air outlet 6 and the installation window 12, and plays a role in heat dissipation for the pump body 8. Compared with the prior art, the technical problem that the service life of the pump body 8 will be affected if the heat dissipation is not good is solved.
[0037] Furthermore, a mesh plate 13 is hinged at the bottom of the installation window 12, a filter plate 20 is detachably provided on the mesh plate 13, a limiting component 7 is arranged on the front side wall of the shell 2 and limits the mesh plate 13, and two L-shaped clamping plates 14 are symmetrically provided on the left and right sides of the rear side wall of the mesh plate 13, and the filter plate 20 is clamped between the two L-shaped clamping plates 14.
[0038] When this technical solution is not provided, the following problems are likely to occur: bolts are usually used to install the filter plate 20, which is troublesome and inconvenient to disassemble and repair at a later stage.
[0039] A mesh plate 13 is hinged at the bottom of the installation window 12, and a filter plate 20 is detachably arranged on the mesh plate 13. A limit assembly 7 for limiting the mesh plate 13 is arranged on the front side wall of the housing 2, and two L-shaped clamping plates 14 are symmetrically arranged on the rear side wall of the mesh plate 13, so that the filter plate 20 is clamped between the two L-shaped clamping plates 14. When in use, the mesh plate 13 is rotated to expose the inner side of the mesh plate 13, and then the old filter plate 20 is pulled out from between the two L-shaped clamping plates 14, and then a new filter plate 20 is installed, which is convenient for replacement. Compared with the prior art, the technical problem that the filter plate 20 is usually installed with bolts and is troublesome and inconvenient to disassemble and repair in the later stage is solved.
[0040] Furthermore, the limiting assembly 7 includes a shell 15 fixedly arranged on the front side wall of the shell 2, a slot 17 opened on the front side wall of the mesh plate 13, an insertion rod 16 penetrating between the shell 15 and the shell 2 and capable of being inserted into the slot 17, a blocking rod 18 located in the shell 15 and fixedly connected to the insertion rod 16, and a limiting spring 19 arranged between the blocking rod 18 and the inner side wall of the shell 15 and sleeved on the insertion rod 16.
[0041] The limiting assembly 7 includes a shell 15 fixedly arranged on the front side wall of the shell 2, a slot 17 is provided on the front side wall of the mesh plate 13, an insertion rod 16 which can be inserted into the slot 17 is provided between the shell 15 and the shell 2, a blocking rod 18 fixedly connected to the insertion rod 16 is provided in the shell 15, and a limiting spring 19 which can be sleeved on the insertion rod 16 is provided between the blocking rod 18 and the inner side wall of the shell 15. The elasticity of the limiting spring 19 is utilized to limit the mesh plate 13. When in use, the insertion rod 16 is inserted into the corresponding slot 17, so that the insertion rod 16 limits the mesh plate 13 to prevent the mesh plate 13 from rotating freely on the installation window 12.
[0042] The above-mentioned implementation modes are only preferred implementation modes of the present application and cannot be used to limit the scope of protection of the present application. Any non-substantial changes and substitutions made by technicians in this field on the basis of the present application shall fall within the scope of protection required by the present application.
Claims
1. A new type of mixing device for suspended matter, characterized in that: The invention comprises an outer shell (2), an inner shell (1) arranged on the inner side of the outer shell (2), the inner shell (1) being used to place the suspended substance, the top of the outer shell (2) being fixedly connected to the top of the inner shell (1) via a connecting plate (3), the outer shell (2) and the inner shell (1) mutually enclose a mounting cavity (22), the bottom of the inner shell (1) is provided with a liquid suction port (4), the bottom of the inner shell (1) is also provided with ten liquid outlets, a pumping and spraying mixing component (21) is provided in the mounting cavity (22), the inlet of the pumping and spraying mixing component (21) is connected to the liquid suction port (4), and the outlet of the pumping and spraying mixing component (21) is connected to the ten liquid outlets. The liquid outlet is connected, the suction-spray mixing component (21) can suck the suspended matter from the liquid suction port (4) and spray it out from the liquid outlet, and the mixing device achieves mixing by suction-spraying the suspended matter through the suction-spray mixing component (21); a heat dissipation component (24) is also provided in the installation cavity (22), and the heat dissipation component (24) plays a role in heat dissipation for the suction-spray mixing component (21), and the heat dissipation component (24) comprises an air outlet (6) provided on the rear side wall of the shell (2), an installation window (12) provided on the front side wall of the shell (2), and a fan (11) provided on the inner side wall of the shell (2).
2. A novel suspended material mixing device according to claim 1, characterized in that: The pumping, spraying and mixing component (21) comprises a pump body (8) fixedly arranged at the bottom of the installation cavity (22), a liquid suction pipe (23) sealed between the liquid suction port (4) and the liquid inlet of the pump body (8), a liquid outlet hard pipe (9) connected to the outlet of the pump body (8), and a liquid outlet hose (10) sealed and connected to the liquid spray port (5), and the other end of the liquid outlet hose (10) is connected to the liquid outlet hard pipe (9).
3. A novel suspended material mixing device according to claim 2, characterized in that: A mesh plate (13) is hingedly connected to the bottom of the installation window (12); a filter plate (20) is detachably provided on the mesh plate (13); and a limiting component (7) is arranged on the front side wall of the housing (2) and limits the mesh plate (13).
4. A novel suspended material mixing device according to claim 3, characterized in that: Two L-shaped clamping plates (14) are symmetrically arranged on the rear side wall of the mesh plate (13), and the filter plate (20) is clamped between the two L-shaped clamping plates (14).
5. A novel suspended material mixing device according to claim 4, characterized in that: The limit assembly (7) comprises a shell (15) fixedly arranged on the front side wall of the shell (2), a slot (17) opened on the front side wall of the mesh plate (13), an insertion rod (16) penetrating between the shell (15) and the shell (2) and capable of being inserted into the slot (17), a stop rod (18) located in the shell (15) and fixedly connected to the insertion rod (16), and a limit spring (19) arranged between the stop rod (18) and the inner side wall of the shell (15) and sleeved on the insertion rod (16).