Sample pretreatment mechanism
By designing the sample pre-processing mechanism, the synergistic effect of the first material collection mechanism, the switch cover mechanism, the second material collection mechanism and the liquid separation mechanism are solved, and efficient and accurate liquid sample assembly is achieved.
Patent Information
- Application Number
- CN202411884883.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-19
- Publication Date
- 2025-03-28
AI Technical Summary
The existing sample packing process is difficult to achieve full process automation, resulting in reduced production efficiency and increased operating errors. Especially when bottling with multiple specifications, it is easy to cause packing errors, affecting production efficiency.
A sample pre-treatment mechanism is designed, including a first material collection mechanism, a switch cover mechanism, a second material collection mechanism and a liquid separation mechanism, and the synergistic effect of these mechanisms realizes automatic transport, opening, absorbing and dispensing of liquid samples.
The automated operation of the sample partitioning process is realized, the efficiency and accuracy of liquid sample partitioning is improved, manual participation is reduced, and the risk of partitioning errors is reduced.
Smart Images

Figure CN119705932A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of sample detection, and in particular to a sample pre-processing mechanism. Background Art
[0002] Sample packaging is one of the production steps in various fields such as petrochemicals, biological testing and reagent production. It is difficult to achieve full process automation due to the complex operation process and the wide variety of materials involved. At present, the sample packaging process is mostly partially automated in structure, combined with manual operation. It is difficult to automate more delicate processes such as opening the lid of the container structure, installing the syringe and filling the sample. This will not only lead to a decrease in production efficiency, but also uncontrollable operational errors due to subjective differences in personnel, which will affect the accuracy of sample packaging. There will also be a risk of packaging errors and shutdown for maintenance and replacement when there are multiple specifications of packaging bottles, affecting production efficiency.
[0003] Therefore, how to improve the efficiency and accuracy of sample packaging is a technical problem that needs to be solved urgently by technical personnel in this field. Summary of the invention
[0004] In view of this, an object of the present invention is to provide a sample pre-processing mechanism to improve the efficiency and accuracy of sample packaging.
[0005] To achieve the above object, the present invention provides the following technical solutions:
[0006] A sample pre-processing mechanism, comprising:
[0007] A first material taking mechanism and a cover opening and closing mechanism, wherein the first material taking mechanism is used to carry a first material to a cover opening position, and the cover opening and closing mechanism opens the cover of the first material at the cover opening position, and the first material is used to accommodate a liquid sample;
[0008] A second material taking mechanism is used to transport a second material to a liquid injection position, wherein the second material is a filling bottle for filling the liquid sample;
[0009] The liquid dispensing mechanism is used to dispense the liquid sample in the first material into the second material, and includes a material taking component and a driving component. The material taking component is used to take a third material, and the third material has an open cavity with a variable volume. The driving component is used to drive the cavity of the third material to change so as to achieve the suction and discharge of the liquid sample by the third material; the operating position of the material taking component at least passes through the cover opening position and the liquid injection position.
[0010] Preferably, the above-mentioned sample pre-processing mechanism comprises a first placing rack and a second placing rack arranged at intervals, wherein the first placing rack is used to place a plurality of the first materials, the cover opening position and the liquid injection position are both located between the first placing rack and the second placing rack; and the liquid separation mechanism is arranged between the first placing rack and the second placing rack.
[0011] Preferably, in the above-mentioned sample pre-processing mechanism, the cover opening and closing mechanism comprises a first cover opening assembly and a second cover opening assembly, the first cover opening assembly comprises a pressing unit and a cover opening unit, the pressing unit is used to limit the first material in a first direction, and the cover opening unit is used to remove the first cover on the first material when the first material is limited by the pressing unit;
[0012] The second cover opening assembly includes a clamping unit and a pressure rod unit. The pressure rod unit is slidably arranged in the first direction to apply a force to the center of the second cover body of the first material and drive the outer wall of the second cover body to expand to unlock the first material. The clamping unit is used to clamp the second cover body from the circumferential direction.
[0013] Preferably, in the above-mentioned sample preprocessing mechanism, the switch cover mechanism also includes a push rod unit, the push rod unit is fixedly arranged on the clamping unit, and the push rod unit and the pressure rod unit are spaced apart in the first direction, and the push rod unit is used to apply a force in the first direction to the second cover body in the opposite direction to the pressure rod unit to drive the outer wall of the second cover body to contract.
[0014] Preferably, in the above-mentioned sample pre-processing mechanism, the cover opening unit includes a plurality of load-bearing claws evenly arranged along the circumferential direction, and a second driving part transmission-connected to the load-bearing claws, the second driving part being used to drive the load-bearing claws to move toward and away from the center of the circle; each load-bearing claw is provided with a clamping claw floatingly on one side toward the center of the circle through at least two elastic members, the clamping claw being used to clamp and lock the first cover body in the first direction.
[0015] Preferably, in the above-mentioned sample pre-processing mechanism, the pressing unit includes a pressing plate and a third driving part, the third driving part is used to drive the pressing plate to move along the first direction, a through hole larger than the first cover body is provided in the middle area of the pressing plate, and the pressing plate abuts against and presses the first material along the circumferential outer side of the first cover body.
[0016] Preferably, the sample pre-processing mechanism further comprises a transfer assembly, wherein the transfer assembly comprises a support portion for carrying the first material, and a fourth drive portion transmission-connected to the support portion; the fourth drive portion is used to drive the support portion to switch between the first station and the second station;
[0017] The first cover opening component opens the first cover body of the first material at the first station, and the second cover opening component opens the second cover body of the first material at the second station. The first station and the second station are arranged along a second direction, and the second direction is perpendicular to the first direction.
[0018] Preferably, in the above-mentioned sample pre-processing mechanism, the material taking assembly comprises a support seat and a clamping portion and a push-pull portion arranged on the support seat, and the driving assembly drives the push-pull portion to slide relative to the clamping portion to move toward and away from the clamping portion;
[0019] The third material includes a fixed part and a moving part which are arranged to slide relative to each other, a cavity is formed between the fixed part and the moving part, and one end of the fixed part is provided with an opening connected to the cavity, and the moving part moves relatively in the fixed part to change the size of the cavity; the clamping part is used to fix the fixed part, and the push-pull part is used to fix the moving part.
[0020] Preferably, in the above sample pre-processing mechanism, the push-pull portion is circumferentially clamped and fixed to the end of the moving portion, and the push-pull portion includes a second pressing plate, which abuts against the end of the moving portion when the push-pull portion and the moving portion are fixed.
[0021] Preferably, in the above-mentioned sample pre-processing mechanism, the liquid dispensing mechanism also includes a mounting frame, the mounting frame includes a liquid receiving portion and a correction portion, the liquid receiving portion is used to limit the second material to the injection position; the correction portion and the injection position are fixed in relative positions on the mounting frame, and the material taking component is filled with the liquid sample into the second material at the injection position after the position is calibrated by the correction portion.
[0022] Preferably, in the above-mentioned sample preprocessing mechanism, the correction part is a closed frame structure and a first sensor and a second sensor are arranged on the inner wall of the frame, the first sensor and the second sensor are linear sensors and their sensing paths intersect, the outer diameter of the injection tip calibrated on the material picking assembly is smaller than the closed frame and is calibrated at the intersection of the first sensor and the second sensor; the sensing paths of the first sensor and the second sensor are vertical.
[0023] Preferably, in the above-mentioned sample preprocessing mechanism, the liquid receiving part includes a support platform and a locking part arranged on the support platform, the support platform can pass through the injection position, and the locking part is used to clamp the second material in the circumferential direction of the second material and can limit the second material to the injection position.
[0024] Preferably, in the above sample pre-processing mechanism, the liquid receiving portion further comprises a fixed seat, a slideway is provided on the fixed seat, the support platform is slidably arranged on the slideway and passes through the liquid injection position, and the support platform is limited by the fixed seat at the liquid injection position.
[0025] Preferably, in the above-mentioned sample preprocessing mechanism, the second material picking mechanism also includes a cover opening part, the support platform also passes through an opening and closing position on the guide path of the slide, and the second material picking mechanism is used to convey the second material to the opening and closing position, and open the cover of the second material through the cover opening part after the locking part locks the second material.
[0026] Preferably, in the above-mentioned sample pre-processing mechanism, any group of the slideways is correspondingly provided with at least one pair of in-place sensors and liquid level sensors, the in-place sensors are used to detect the movement of the second material at the injection position into position, and the liquid level sensors are used to detect the filling level in the second material.
[0027] Preferably, in the above-mentioned sample preprocessing mechanism, a plurality of tray racks are arranged in the second placement rack, and a single tray rack is used to accommodate a plurality of the second materials; a plurality of groups of the second material picking mechanism are arranged to clamp and open the plurality of the second materials at the same time, and the second material picking mechanism can clamp and transport a plurality of the second materials at the same time by clamping the tray rack.
[0028] It can be seen from the above technical scheme that the sample pre-processing mechanism provided by the present invention realizes the position transfer of two materials, namely, the first material for accommodating liquid samples and the second material for dispensing liquid samples, through the first material taking mechanism and the second material taking mechanism. For the first material, the cover is opened by the switch cover mechanism so that the liquid in the first material can be absorbed by the third material taken by the liquid dispensing mechanism. The liquid dispensing mechanism can switch between the cover opening position and the liquid injection position, so that the third material can absorb the liquid sample in the first material through the action of the driving component at the cover opening position, and at the same time, the liquid sample in the third material is added to the second material at the liquid injection position, and the second material with completed liquid injection is removed through the transfer action of the second material taking mechanism to complete the dispensing of a single liquid sample. The above process can realize automatic operation through the synergistic action of each mechanism without manual participation, which optimizes the degree of automation in the liquid sample dispensing process and improves the efficiency and accuracy of liquid sample dispensing. BRIEF DESCRIPTION OF THE DRAWINGS
[0029] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0030] Figure 1 A schematic diagram of the structure of a sample pre-processing mechanism provided in an embodiment of the present invention;
[0031] Figure 2 for Figure 1 A schematic diagram of the integrated structure of the first reclaiming mechanism and the reclaiming assembly;
[0032] Figure 3 It is a schematic diagram of the switch cover mechanism structure;
[0033] Figure 4 for Figure 3 A schematic diagram of the structure of the second opening cover assembly;
[0034] Figure 5 for Figure 3 A schematic diagram of the structure of the first cover opening component;
[0035] Figure 6 for Figure 5 Schematic diagram of the cross-sectional structure of the middle load-bearing claw position;
[0036] Figure 7 It is a schematic diagram of the material taking component clamping the third material;
[0037] Figure 8 It is a detailed structural diagram of the clamping part;
[0038] Fig. 9 It is a schematic diagram of the mounting bracket position structure;
[0039] Fig.10 for Fig. 9 Schematic diagram of the structure of the central part;
[0040] Fig.11 It is a schematic diagram of the fixed seat structure.
[0041] Among them: 10-first material taking mechanism; 20-opening cover mechanism; 210-first cover opening assembly; 2110-pressing unit; 21110-pressing plate; 21120-through hole; 2120-cover opening unit; 21210-carrying claw; 21220-elastic member; 21230-holding claw; 21240-limiting protrusion; 220-second cover opening assembly; 2210-clamping unit; 22110-clamping claw; 22120-visual sensor; 2220-pressing rod unit; 30-second material taking mechanism; 310-cover opening part; 40-liquid separation mechanism; 410-material taking assembly; 4110-clamping part; 41110-clamping block; 41120-first press plate; 4120-pushing and pulling part; 4121 0-second pressure plate; 420-mounting frame; 4210-liquid receiving part; 42110-support table; 42120-locking part; 42130-fixed seat; 42140-slide; 42150-in-place sensor; 4220-correction part; 42210-first sensor; 42220-second sensor; 50-transfer component; 510-support part; 520-baffle; 610-first placement rack; 620-second placement rack; 630-third placement rack; 710-first material; 7110-first cover body; 7120-second cover body; 720-second material; 730-third material; 7310-fixed part; 73110-raised part; 7320-moving part; 80-guide rail bracket. DETAILED DESCRIPTION
[0042] The core of the present invention is to disclose a sample pre-processing mechanism to improve the efficiency and accuracy of sample packaging.
[0043] In order to make the technical personnel in this field better understand the scheme of the present invention, the embodiments of the present invention are described below with reference to the accompanying drawings. In addition, the embodiments shown below do not limit the content of the invention recorded in the claims. In addition, the entire contents of the structures represented by the following embodiments are not limited to those necessary for the solutions of the invention recorded in the claims.
[0044] like Figure 1 As shown, the sample pre-processing mechanism provided by the embodiment of the present invention mainly includes a first material picking mechanism 10, a cover opening and closing mechanism 20, a second material picking mechanism 30 and a liquid dispensing mechanism 40, wherein the first material picking mechanism 10 is used to transport the first material 710 to the cover opening position. It should be noted that the first material 710 is used to accommodate liquid samples, which can be a commonly used container such as an oil drum, and the first material picking mechanism 10 is used to clamp the first material 710 and move it to the cover opening position under the guidance of the guide rail bracket 80, and release the first material 710 after placing the first material 710 at the cover opening position; the first material picking mechanism 10 is simple in execution and the operation process is simple, which can ensure the accurate setting of the first material 710.
[0045] The switch cover mechanism 20 is used to open the cover of the first material 710 at the open cover position. Since the first material 710 is used to store a large amount of liquid samples, it is usually provided with a sealed and anti-collision cover to protect the internal liquid samples. Therefore, the switch cover mechanism 20 needs to be provided so that the first material 710 can expose the internal liquid samples at the open cover position. On this basis, the liquid dispensing mechanism 40 includes a material taking component 410 and a driving component, wherein the material taking component 410 is used to take the third material 730. It should be noted here that the third material 730 is used to inhale and discharge liquid samples. It has a cavity with a variable volume and a single opening area, so that when the volume of the cavity changes, liquid can be inhaled or discharged from the opening through negative pressure. The third material 730 can be a commonly used syringe structure; the material taking component 410 is used to clamp and take out the third material 730 at the corresponding position, and can drive the third material 730 to switch between the cover opening position and the injection position under the drive of the liquid dispensing structure. The driving component is used to drive the third material 730 to realize the volume change of the cavity. The cooperation between the material taking component 410 and the driving component can realize that the third material 730 absorbs the liquid sample in the first material 710 at the cover opening position and discharges the liquid sample at the injection position.
[0046] On the basis of the above structure, the second material taking mechanism 30 is used to transport the second material 720 to the injection position, and it should be noted that the second material 720 is used to pack liquid samples, which can be a variety of specifications of the packing bottles; and similar to the first material taking mechanism 10, the second material taking mechanism 30 can clamp the second material 720 by clamping, and after moving to the injection position under the guidance of the guide rail bracket 80, release the second material 720 so that the second material 720 is located at the injection position; combined with the action of the liquid separation structure in the above embodiment, the liquid sample packing of the second material 720 at the injection position can be realized. And after the second material 720 completes the liquid sample packing, it can also be moved away by the clamping and transporting action of the second material taking mechanism 30, and the cyclic action can be realized to realize the liquid sample packing of multiple second materials 720.
[0047] The above-mentioned embodiment can realize the automated transfer of liquid sample containers, opening of lids, and liquid sample aspiration through the coordinated actions of the first material taking mechanism 10, the cover opening mechanism 20, the second material taking mechanism 30, and the liquid separation structure. At the same time, combined with the automated transfer of the filling bottles, the filling and removal of liquid samples, the entire liquid sample filling process can be automated, thereby reducing manual intervention and improving the efficiency and accuracy of the liquid sample filling process.
[0048] Furthermore, in order to improve the coordination of the actions of various mechanisms and reduce the stroke, in some embodiments of the present invention, the sample pre-processing mechanism includes a first placement rack 610 and a second placement rack 620 arranged at intervals, wherein the first placement rack 610 is used to place multiple first materials 710, and it should be noted that the bottom of the first placement rack 610 preferably adopts a three-section track to achieve sliding, and the three-section track can make the first placement rack 610 completely slide out of its basic bearing structure without interference, so as to facilitate the loading of the first material 710 on the first placement rack 610; correspondingly, the movement range of the first material picking mechanism 10 on the guide rail bracket 80 covers the entire area of the first placement rack 610 and the cover opening position, so as to be able to transport the first material 710 at any position on the first placement rack 610 to the cover opening position.
[0049] The second rack 620 is used to place multiple second materials 720, and the movement range of the second material picking mechanism 30 covers any position and the injection position of the second rack 620, so that the second material 720 at any position on the second rack 620 can be transferred to the injection position. On this basis, the opening position and the injection position are both located between the first rack 610 and the second rack 620, and are arranged between the two side walls facing the first rack 610 and the second rack 620 to balance the movement distance of the first material picking mechanism 10 and the second material picking mechanism 30. At the same time, the liquid separation mechanism 40 is also arranged between the first rack 610 and the second rack 620, so that the liquid separation mechanism 40 has the minimum running distance when switching between the opening position and the injection position, thereby improving the movement speed of the liquid separation mechanism 40 and improving the liquid sample packaging efficiency.
[0050] It should be noted that, in some embodiments of the present invention, the third material 730 needs to be replaced, and therefore a third placement rack 630 for storing multiple third materials 730 is also provided at the peripheral position of the first placement rack 610, and it should be noted that the third placement rack 630 preferably has a multi-layer structure, and the opening of the top layer is used for placing the third material 730, and the limiting layer which is lower in height than the top layer is used for limiting and clamping the third material 730; the limiting layer is preferably adjustable in distance from the top layer, and for third materials 730 of different heights, the third material 730 can be lifted or lowered by adjusting the relative distance between the limiting layer and the top layer to change the size of the third material 730 exceeding the top layer, thereby providing sufficient clamping space for the material picking component 410 to achieve smooth clamping of the third material 730.
[0051] Furthermore, in the sample pre-processing mechanism provided in the embodiment of the present invention, Figure 2-6As shown, the cover opening and closing mechanism 20 mainly includes a first cover opening component 210 and a second cover opening component 220. In one embodiment, the first cover opening component 210 and the second cover opening component 220 can be arranged on the same support structure to realize synchronous driving, and realize the independent action process of the first material 710 through the spaced structure; at the same time, they can also be arranged on different support structures to realize independent transfer actions.
[0052] Among them, the first opening cover component 210 is used to perform the opening action on the first cover body 7110 on the first material 710. The first opening cover component 210 mainly includes a clamping unit 2110 and an opening cover unit 2120. The clamping unit 2110 and the opening cover unit 2120 cooperate to realize the removal of the first cover body 7110 in the first direction. Specifically, the clamping unit 2110 is used to limit the first material 710 in the first direction, where the first direction is the height direction of the first material 710 in the placed state. When the first material 710 is maintained in a horizontally placed state, the first direction is the vertical direction. Since the first opening cover component 210 needs to remove the first cover body 7110 in the first direction, the first material 710 is limited in the first direction by the clamping unit 2110; the clamping unit 2110 can achieve compression of the first material 710 by means of a plate or a protruding rod to abut against the top wall surface of the first material 710 in the first direction, thereby preventing the first material 710 from moving along the first direction when the opening cover unit 2120 removes the first cover body 7110.
[0053] The cover opening unit 2120 is used to remove the first cover body 7110 on the first material 710 in the first direction. Here, the cover opening unit 2120 can clamp the first cover body 7110 and remove the first cover body 7110 by screwing, or can clamp the first cover body 7110 and remove the first cover body 7110 by clamping and pulling. At the same time, the cover opening unit 2120 can also adopt a combination of the two structures, that is, it can perform a rotating cover opening action, and can also perform a clamping cover opening action. It should be noted that since the first cover body 7110 is mostly a protective cover body with higher rigidity on the first material 710, the first opening cover component 210 can be opened by a destructive opening method, through the clamping limit of the clamping unit 2110 and the clamping action of the opening cover unit 2120. For the pull-out type cover body structure, it can be clamped by the opening cover unit 2120, and the first opening cover component 210 can be driven along the first direction by the driving component on the first opening cover component to directly pull the first cover body 7110; for the screw-type cover body structure, the driving component needs to be rotatably connected to the opening cover unit 2120, so that after the opening cover unit 2120 is locked and matched with the first cover body 7110, the first cover body 7110 can be removed by the rotational driving action of the driving component.
[0054] It should be noted that, in some embodiments of the present invention, the driving component can simultaneously set two driving forms of the opening cover unit 2120, namely, linear motion along the first direction, and rotational drive with the axis of the first cover body 7110 as the rotation center, and different opening methods are adopted according to different structural forms of the first cover body 7110.
[0055] The second cover opening component 220 is used to open the second cover body 7120 of the first material 710, so as to cooperate with the first cover opening component 210 to complete the entire cover opening action; the second cover opening component 220 can have the same structure as the first cover opening component 210 to open the first cover body 7110 and the second cover body 7120 of similar structure, or to simultaneously operate two first materials 710 with single-layer cover bodies to improve the opening efficiency of the opening and closing cover mechanism 20; and the second cover opening component 220 can also have a different structure from the first cover opening component 210, so as to open the two layers of different cover structures of a single first material 710. In some embodiments of the present invention, the second cover opening assembly 220 mainly includes a clamping unit 2210 and a pressure rod unit 2220 to open the second cover body 7120 with a circumferential slit structure. Specifically, the pressure rod unit 2220 is connected to a driving component such as a motor or a cylinder to achieve sliding in the first direction, and the transfer component of the second cover opening assembly 220 can move the pressure rod unit 2220 to the top of the second cover body 7120 in the first direction. The upward position adjustment can apply a force from the top of the second cover body 7120 to the center of the second cover body 7120, so that the outer wall of the second cover body 7120 can expand and realize the unlocking of the second cover body 7120 and the first material 710. After the pressure rod unit 2220 completes the unlocking action of the second cover body 7120, the clamping unit 2210 can clamp the second cover body 7120 from the circumferential direction and complete the opening action of the second cover body 7120 under the transfer action of the clamping unit 2210.
[0056] It should be noted that, when removing the second cover 7120, the clamping unit 2210 only applies the clamping force required for transportation to the second cover 7120, and after removing the second cover 7120, it leaves the opening area of the first material 710 to temporarily store the second cover 7120; and when there is still liquid material in the first material 710 and the packaging process is completed, the clamping unit 2210 is able to drive the second cover 7120 back to the opening position of the first material 710 to reset the second cover 7120.
[0057] The switch cover mechanism 20 provided in the above embodiment can realize the opening of two covers with different structures by setting the first cover opening component 210 and the second cover opening component 220. For the cover body with a fixed buckle arrangement, the first cover opening component 210 can be used to press and limit the cover body, and the cover can be opened by clamping; for the cover body with a peripheral shrink buckle, the second cover opening component 220 can be used to apply a central force to drive the outer wall to deform, so as to realize opening, and the clamping can be achieved by the clamping unit 2210; thereby, the switch cover mechanism 20 can open the first material 710 having one or both of the two cover bodies, thereby improving the versatility of the switch cover mechanism 20. At the same time, for the recoverable deformation structure of the second cover body 7120, the clamping unit 2210 of the second opening cover assembly 220 in the embodiment of the present invention can realize temporary storage. When the first material 710 needs to be closed and the operation is suspended, the clamping unit 2210 can also drive the second cover body 7120 to move to the opening area of the first material 710 to close the cover of the first material 710, thereby meeting the closing requirements of the first material 710 during use.
[0058] On the basis of the above-mentioned embodiment, when the second cover 7120 needs to be closed, since the second cover 7120 is unlocked from the first material 710 by expanding and deforming the outer wall, it is necessary to apply a driving force to the outer wall of the second cover 7120 to deform toward the middle area. In some embodiments of the present invention, the clamping unit 2210 of the second cover opening assembly 220 has a driving gear that further contracts toward the center on the basis of contracting toward the center to clamp the second cover 7120. When the clamping unit 2210 clamps and temporarily stores the second cover 7120, if the second cover 7120 needs to be closed, the clamping unit 2210 further contracts toward the center to apply a force toward the center from the circumferential outer wall of the second cover 7120 to the second cover 7120, and drives the outer wall of the second cover 7120 to contract to a state where it can be docked and locked with the opening of the first material 710, and the clamping unit 2210 then drives the second cover 7120 to buckle with the opening of the first material 710. It should be noted that, during the above-mentioned closing process, the clamping unit 2210 can also firstly put the second cover body 7120 on the opening position of the first material 710, and then drive the outer wall of the second cover body 7120 to shrink and directly lock with the first material 710 by further contracting toward the center, which can smoothly realize the closing action of the second cover body 7120 on the first material 710.
[0059] In order to avoid the risk of irregular deformation of the second cover body 7120 when the clamping unit 2210 drives the outer wall of the second cover body 7120, in some embodiments of the present invention, the second opening cover assembly 220 also includes a push rod unit, and the push rod unit and the pressure rod unit 2220 are spaced apart and oppositely arranged in the first direction. The opposite arrangement here means that the push rod unit and the pressure rod unit 2220 are located on both sides of the second cover body 7120 in the first direction. Correspondingly, when the second cover body 7120 is expanded and deformed by the action of the pressure rod unit 2220, when it is necessary to close the cover, the push rod unit is actuated, or the clamping unit 2210 drives the second cover body 7120 to move, so that the push rod unit contacts and acts on the central area of the second cover body 7120. The push rod unit and the pressure rod unit 2220 are arranged on opposite sides of the second cover body 7120, so that the push rod unit can apply a force to the second cover body 7120 in a first direction that is opposite to the action direction of the pressure rod unit 2220, thereby causing the outer wall of the second cover body 7120 to shrink toward the center under the action of the push rod unit, and return to its original state and be able to dock and lock with the opening of the first material 710. It should be noted that the push rod unit applies force to the second cover body 7120 from the center, which can make the outer wall of the second cover body 7120 produce more regular deformation, and the push rod unit and the pressure rod unit 2220 are structures that apply force from the same area on both sides of the second cover body 7120. When certain irregular deformations occur, they can also offset each other to make the second cover body 7120 meet a more regular closed state.
[0060] Further, on the basis of the above embodiment, in order to reduce the structural complexity of the switch cover mechanism 20, the push rod unit is preferably fixedly arranged, which can be a rod structure with a protruding arrangement, and the second cover body 7120 is deformed by the action of the clamping unit 2210 driving the second cover body 7120. It should be noted that since the clamping unit 2210 itself is a moving part, it can be driven by the driving structure to drive the second cover body 7120 to move toward the push rod unit, without the need to design the push rod unit as a moving part to increase the demand for interference adjustment, thereby reducing the complexity of the structure. Since the pressing unit 2110 has a certain height and is a stable bearing platform, the push rod unit is fixedly arranged on the pressing unit 2110 to reduce the stroke of the clamping unit 2210 carrying the second cover body 7120 in contact with the push rod unit and reduce the material consumption in the process of setting the push rod unit structure.
[0061] In addition, it should be noted that in some embodiments of the present invention, the clamping unit 2210 includes a pair of jaws 22110, which are symmetrically arranged and contracted and expanded by the first driving unit to change the distance between the two jaws 22110, so as to meet the clamping and loosening actions of the clamping unit 2210 on the second cover 7120 and meet the requirements of opening and closing the cover of the second cover 7120. It should also be noted that in order to avoid the influence of the second cover 7120 on the subsequent liquid extraction process, a visual sensor 22120 is also provided on the clamping unit 2210, and the detection range of the visual sensor 22120 covers the jaws 22110, and the visual sensor 22120 is connected in communication with the driving component of the clamping unit 2210 to adjust the action of the driving component through information feedback. During the process of opening the second cover body 7120, the clamping unit 2210 contacts the second cover body 7120 and clamps the second cover body 7120 through the driving action of the first driving unit. At the same time, the visual sensor 22120 detects the existence of the second cover body 7120 between the clamping jaws 22110, and then it will feedback the driving component of the clamping unit 2210 to continue to move, and drive the second cover body 7120 to leave the opening area of the first material 710. Once the visual sensor 22120 detects that there is no second cover body 7120 between the clamping jaws 22110, it means that the opening process of the second cover body 7120 has failed. Then the visual sensor 22120 feedbacks the driving component of the clamping unit 2210 to stop moving, and prompts the operator to retry the opening action of the second cover body 7120 through sound and light signals, or shut down for maintenance, so as to avoid failure of the subsequent liquid extraction process.
[0062] Furthermore, in the cover opening and closing mechanism 20 provided in the embodiment of the present invention, the clamping unit 2210 and the pressure rod unit 2220 are arranged at intervals to avoid interference between the opening process and the clamping process of the second cover body 7120, and it should be noted that the clamping unit 2210 and the pressure rod unit 2220 can be arranged independently to achieve driving through different driving parts, and the clamping unit 2210 and the pressure rod unit 2220 can also be arranged as an integrated structure, that is, both are arranged on the same support and achieve position adjustment through the same driving part. When one of the clamping unit 2210 and the pressure rod unit 2220 moves, the other follows the movement and avoids motion interference through the structure arranged at intervals.
[0063] Further, for the cover opening and closing mechanism 20 provided in the embodiment of the present invention, in the first cover opening assembly 210 for realizing the cover opening action of the first cover body 7110, the cover opening unit 2120 includes a plurality of bearing claws 21210, and the bearing claws 21210 are evenly arranged along the circumferential direction. It should be noted that three or more bearing claws 21210 are preferably arranged to reduce the risk of deflection of the first cover body 7110 during the action of the cover opening unit 2120. The bearing claws 21210 are transmission-connected to the second driving part, so that the bearing claws 21210 can move toward and away from the center of the circle through the second driving part, that is, the contraction and expansion of the clamping area between the bearing claws 21210 can be realized through the second driving part.
[0064] The cover opening unit 2120 can clamp the first cover body 7110 through the structure of the second driving part and the bearing claw 21210. However, for the annular first cover body 7110 structure, the bearing claw 21210 may slip during the cover opening process due to the difference in centering, small clamping force, and the overly firm connection between the first cover body 7110 and the first material 710. Therefore, based on the above embodiment, each bearing claw 21210 is also provided with a clamping claw 21230 on the side facing the center of the circle, and the cover opening unit 2120 locks the first cover body 7110 through the clamping claw 21230. It should be noted that the clamping claws 21230 and the bearing claws 21210 are arranged in a one-to-one correspondence, and the floating clamping claws 21230 can have a certain deformation range in the radial direction of the clamping structure. On this basis, when the cover opening unit 2120 is clamping the first cover body 7110, if there is a certain difference in the degree of centering, the floating clamping claws 21230 can compensate for the error. Specifically, the clamping claws 21230 closer to the edge of the first cover body 7110 float to the distance from the corresponding The load-bearing claw 21210 is located closer to the position, while the clamping claw 21230 that is farther away from the edge of the first cover body 7110 floats to a position farther away from its corresponding load-bearing claw 21210. It only needs the action of the second driving unit to make the floating structure of each clamping claw 21230 in a compressed state. In the condition where there is a centering error between the opening unit 2120 and the first cover body 7110, the structure of the clamping claw 21230 can still be used to achieve adhesion and clamping with the outer wall of the first cover body 7110.
[0065] Considering that the first cover body 7110, as an outer cover structure, usually has higher strength and a tighter connection effect, in some embodiments of the present invention, the clamping claw 21230 is also provided with a limiting protrusion 21240 on its inner wall surface facing the center of the circle, so as to improve the stability of the first cover body 7110 during the pulling process by abutting and limiting the limiting protrusion 21240 with the first cover body 7110. Preferably, the limiting protrusion 21240 is arranged at one end of the clamping claw 21230 in the first direction. When the clamping claw 21230 contacts the outer wall of the first cover body 7110, the limiting protrusion 21240 is stuck between the first cover body 7110 and the main structure of the first material 710. Here, when the opening unit 2120 is lifted in the first direction to pull the first cover body 7110, the friction effect of the inner wall of the clamping claw 21230 under the clamping force and the abutment and limiting effect of the circumferential limiting protrusion 21240 on the edge of the first cover body 7110 can enhance the pulling force of the opening unit 2120 on the first cover body 7110 in the first direction, thereby enhancing the stability of the opening process of the first cover body 7110.
[0066] It should also be noted that the floating setting of the clamping claw 21230 can be achieved by an elastic member 21220 such as a spring, and in order to enhance the stability of the floating structure, it is preferred that a single load-bearing claw 21210 is provided with at least two elastic members 21220 spaced apart in the first direction, so as to enhance the stability of the floating process by means of two-point auxiliary action. At the same time, in order to avoid the structural influence of the elastic member 21220 on the cover opening unit 2120, it is preferred that the clamping claw 21230 is provided at the end position of the elastic member 21220, and the other end of the elastic member 21220 is provided on the inner wall of the load-bearing claw 21210, or is provided through the load-bearing claw 21210; it is only necessary to ensure that there is no protruding mechanism on the inner wall of the clamping claw 21230 to affect its clamping effect on the first cover body 7110.
[0067] Furthermore, in the switch cover mechanism 20 provided in the embodiment of the present invention, the clamping unit 2110 is an important component for achieving the stability of the first material 710 during the opening process of the first cover body 7110, and specifically includes a pressing plate 21110 and a third driving part, the third driving part is used to drive the pressing plate 21110 to move in the first direction, so that the first material 710 can be placed directly below the pressing plate 21110 after the pressing plate 21110 is lifted, or the pressing plate 21110 can be transferred directly above the first material 710 without interfering with the first material 710; at the same time, after the pressing plate 21110 is located directly above the first material 710, the third driving part drives the pressing plate 21110 to descend in the first direction to contact with the top wall surface of the first material 710 to limit the lifting movement of the first material 710 in the first direction, thereby avoiding the risk of shaking or movement of the first material 710 when the first cover body 7110 is lifted in the first direction.
[0068] Furthermore, the pressing plate 21110 may be a split structure and limit the first material 710 from multiple areas of the top wall of the first material 710, and the pressing plate 21110 may also be an integral plate structure. In some embodiments of the present invention, a through hole 21120 is provided in the middle area of the pressing plate 21110, and the size of the through hole 21120 is larger than the size of the first cover 7110 to allow the first cover 7110 to pass through the through hole 21120. On this basis, when the pressing plate 21110 compresses the first material 710, the through hole 21120 is aligned with the first cover 7110, and under the driving action of the third driving unit, the pressing plate 21110 abuts against and compresses the first material 710 along the circumferential outer side of the first cover 7110, which can apply a stable pressing force on the circumference of the first cover 7110 when the first cover 7110 is opened to improve the stability of the first material 710.
[0069] In addition, it should be noted that since the first cover body 7110 is mostly a disposable structure, and the first cover opening component 210 opens the rigid first cover body 7110, the first cover body 7110 will have the risk of destructive deformation, so in some embodiments of the present invention, the cover opening and closing mechanism 20 also includes a storage component for collecting the first cover body 7110, the storage component is a cavity storage structure with a top opening, and the movement position of the cover opening unit 2120 includes the upper part of the storage component. After the cover opening unit 2120 completes the removal of a single first cover body 7110, the cover opening unit 2120 is driven by the transfer mechanism of the first cover opening component 210 to move to the upper part of the storage component, and then the second driving part drives the bearing claw 21210 to move away from the center of the circle to release the first cover body 7110, so that the cover opening unit 2120 can cyclically open the cover of the first cover body 7110 of multiple first materials 710.
[0070] At the same time, in the above embodiment, the driving part used for structural driving can be a commonly used power component such as a motor and a cylinder; at the same time, sensors can also be set for detection for the position where the movement needs to be confirmed to be in place, and the area where there is movement interference. When there is a problem with the first material 710 or other structural parts being in place, and a problem with interference between the moving parts 7320, the sensor feedback controller stops the action of the switch cover mechanism 20 and prompts the operator to perform maintenance. The driving method and the sensing method are commonly used technical means by technicians in this field, and will not be repeated here.
[0071] In order to further optimize the above technical solution, in some embodiments of the present invention, the cover opening and closing mechanism 20 further includes a transfer assembly 50. Specifically, the transfer assembly 50 includes a support portion 510 and a fourth drive portion, wherein the support portion 510 is used to carry the container, and is slidably arranged on the support structure, and realizes sliding motion through the fourth drive portion. The slidably arranged support portion 510 can cooperate with the feeding mechanism of the first material 710 by setting a sliding path, that is, the support portion 510 can slide to a position where the feeding mechanism is convenient for unloading, and carry the first material 710, and then rotate to the operating position of the cover opening and closing mechanism 20 by sliding action to open the cover of the first material 710. It can optimize the workflow, and keep sufficient design spacing between different structures, reducing the design difficulty.
[0072] In order to facilitate the execution of the cover opening process, the fourth driving part is used to drive the support part 510 to switch between the first station and the second station, wherein the interval between the first station and the second station can be set according to the needs to ensure that there is no interference problem when the cover opening structures on the two stations are in motion. Correspondingly, the first cover opening component 210 can open the first cover body 7110 of the first material 710 at the first station, and the second cover opening component 220 can open the second cover body 7120 of the first material 710 at the second station, and the two cover opening components will not affect each other. On the basis of the above structure, the second station can be extended to allow the first material picking mechanism 10 to have a larger operating space for the unloading and placing process of the first material 710; at this time, the feeding mechanism first unloads the first material 710 from the second station, the support portion 510 is first located at the second station and carries the first material 710, and the fourth driving portion drives the support portion 510 to move to the first station, and opens the first cover body 7110 on the first material 710 through the first opening cover assembly 210; after the first cover body 7110 is opened, the fourth driving portion drives the support portion 510 to move to the first station, and ... The movable support part 510 moves to the second station, and the second cover body 7120 on the first material 710 is opened and temporarily stored through the second opening cover assembly 220. The first material 710 after opening can be transferred to a position suitable for liquid extraction through the support part 510 under the drive of the fourth driving part, or liquid can be extracted at the second station; when it is necessary to close the opened first material 710, the first material 710 is adjusted to the second station, and then the second opening cover assembly 220 is used to realize the closing action of the second cover body 7120 on the first material 710.
[0073] It should be noted that the first workstation and the second workstation are preferably arranged along the second direction to reduce the difficulty of driving the support part 510 by the fourth driving part through sliding in a single direction, and the second direction is preferably perpendicular to the first direction, that is, the first direction is along the vertical direction and the second direction is set along the horizontal direction.
[0074] Furthermore, in order to prevent the first material 710 from shaking and tipping over during the transfer process through the support portion 510, the transfer assembly 50 also includes a baffle 520. The baffle 520 can be arranged in pairs to abut against the opposite side outer walls of the first material 710 in the second direction to maintain the stability of the first material 710 during movement.
[0075] As for the liquid separation mechanism 40 in the sample pre-processing mechanism provided in the embodiment of the present invention, Figure 7 and Figure 8 As shown, the material taking assembly 410 includes a support seat, a clamping portion 4110 and a push-pull portion 4120 arranged on the support seat, wherein the support seat is a basic bearing structure, and the clamping portion 4110 and the push-pull portion 4120 are both arranged on the support seat, and in particular, the push-pull portion 4120 is slidably arranged relative to the clamping portion 4110, so that it can move toward and away from the push-pull portion 4120 under the driving action of the driving assembly. It should be noted that in some embodiments of the present invention, the clamping portion 4110 is fixedly arranged on the support seat by bolts, and a slide groove is also arranged on the support seat, and a protrusion is arranged on one side of the push-pull portion 4120 to be inserted into the slide groove, so that the push-pull portion 4120 can slide relative to the clamping portion 4110 in the guiding direction of the slide groove, and the movement drive of the push-pull portion 4120 can be realized by a commonly used power element such as a motor, a cylinder or a hydraulic cylinder, which will not be repeated here.
[0076] Correspondingly, the third material 730 includes a fixed part 7310 and a moving part 7320, and the fixed part 7310 and the moving part 7320 are arranged to form a cavity with a single opening, so that the liquid sample can be absorbed and filled from the opening position of the cavity, and the opening of the cavity is arranged at one end of the fixed part 7310, and the fixed part 7310 and the moving part 7320 are arranged to slide relative to each other. The cavity with only a single opening can expand the cavity structure when the fixed part 7310 and the moving part 7320 slide relative to each other, forming a cavity with a negative pressure state and absorbing the liquid sample, and can also shrink the cavity structure when the fixed part 7310 and the moving part 7320 slide relative to each other, so that the liquid sample inside the cavity can flow out from the opening position for filling.
[0077] As for the material picking component 410 in the above embodiment, the clamping part 4110 is used to fix and lock the fixed part 7310 in the third material 730 so that the clamping part 4110 and the fixed part 7310 maintain the same operating state; and the push-pull part 4120 is used to be fixedly connected with the moving part 7320 in the third material 730. Based on the assembly relationship between the clamping part 4110 and the push-pull part 4120 on the support seat, after the clamping part 4110 is connected to the fixed part 7310 and the push-pull part 4120 is fixed to the moving part 7320, the push-pull part 4120 drives the moving part 7320 to move away from and approach to the fixed part 7310 by performing the movement action relative to the clamping part 4110. The cavity structure formed by the moving part 7320 and the fixed part 7310 can produce spatial changes, thereby realizing the absorption and filling of liquid samples.
[0078] Further, in some embodiments of the present invention, the clamping portion 4110 includes a plurality of clamping blocks 41110 arranged at intervals, and the clamping block 41110 is connected to a driving portion for adjusting the opening and clamping range of the clamping block 41110. The clamping block 41110 is preferably opened on one side to improve the convenience of the clamping effect. It should be noted that the outer diameter of the fixing portion 7310 is within the clamping range of the clamping block 41110. On this basis, the clamping block 41110 can be opened under the action of the driving portion, and its clamping size is larger than the outer diameter of the fixing portion 7310, and the clamping portion 4110 is driven to move toward the third material 730 through the support seat, so as to realize the clamping block 41110 opening to the fixing portion 7310; after the clamping block 41110 completes the clamping of the fixing portion 7310, the driving portion drives the clamping block 41110 to contract to realize the rapid clamping of the fixing portion 7310. Similarly, when the used third material 730 needs to be released, the clamping block 41110 only needs to be opened to unlock the fixing portion 7310, thereby achieving the removal of the third material 730.
[0079] Based on the above embodiment, at least two groups of clamping blocks 41110 are preferably arranged in parallel, and the two groups of clamping blocks 41110 are arranged at intervals along the axial direction of the third material 730 to improve the clamping stability of the clamping part 4110 on the fixing part 7310, so as to avoid the fixing part 7310 slipping when the clamping force of a single group of clamping blocks 41110 fails, thereby affecting the production process.
[0080] Furthermore, in order to improve the connection stability of the clamping portion 4110 to the fixing portion 7310, in some embodiments of the present invention, the clamping portion 4110 also includes a first pressure plate 41120, and correspondingly, a protrusion 73110 is provided on the outer wall of the fixing portion 7310, and the protrusion 73110 protrudes based on the outer wall of the fixing portion 7310 in a direction away from the axis of the fixing portion 7310, and the first pressure plate 41120 is used to clamp and limit the protrusion 73110. Since the connection between the clamping portion 4110 and the fixed portion 7310 is achieved through the friction between the clamping block 41110 and the fixed portion 7310, when the clamping portion 4110 drives the moving portion 7320 to slide relative to the fixed portion 7310 to achieve the absorption and discharge of the liquid sample in the third material 730, the fixed portion 7310 will be subjected to an axial force, and there is a risk of overcoming the friction force and sliding relative to the clamping portion 4110. Therefore, a first pressure plate 41120 is provided to enhance the stability of the fixed portion 7310 during the absorption and discharge of the liquid sample.
[0081] In some embodiments of the present invention, the first pressing plate 41120 is spaced apart from the edge of a single clamping block 41110 in the axial direction of the fixing portion 7310. The space between the clamping block 41110 and the first pressing plate 41120 is used to limit the fixing portion 7310 in the axial direction of the fixing portion 7310. The first pressing plate 41120 only needs to be a single-layer plate structure to cooperate with the clamping block 41110 to achieve the limited locking of the fixing portion 7310. In other embodiments of the present invention, the first pressing plate 41120 has a recessed groove structure to clamp the protrusion 73110 in the axial direction of the fixing portion 7310. It should be noted that the recessed groove can be a recessed setting of a single pressing plate 21110 or can be formed by two spaced pressing plates 21110. It is only necessary to satisfy the structure on the material taking assembly 410 that can clamp the limiting protrusion 21240 in the axial direction.
[0082] Furthermore, in the material picking assembly 410 provided in the embodiment of the present invention, the raised portion 73110 arranged on the outer wall of the fixed portion 7310 is preferably arranged as an annular structure to have a circumferential protrusion in all directions, so that when the clamping portion 4110 is connected to the fixed portion 7310 at any angle, the first pressure plate 41120 can dock with a partial area of the raised portion 73110 to achieve the limitation of the fixed portion 7310. It should be noted that the protrusion 73110 is preferably arranged at the end edge of the fixing portion 7310 to avoid the influence of the protrusion 73110 on the main structure of the fixing portion 7310. The clamping block 41110 can connect and fix the main body in the main area of the fixing portion 7310, and the first pressure plate 41120 can lock the fixing portion 7310 at the end of the fixing portion 7310. When the first pressure plate 41120 cooperates with a single clamping block 41110 to perform axial compression of the fixing portion 7310, the clamping block 41110 can also be arranged at the end position of the fixing portion 7310, and can cooperate with other clamping blocks 41110 to achieve the effect of connecting and locking the fixing portion 7310 at the two end positions of the fixing portion 7310 in the axial direction, thereby improving the connection stability of the fixing portion 7310 and reducing the risk of deflection of the fixing portion 7310 when the moving portion 7320 produces relative movement.
[0083] In addition, considering that the first pressure plate 41120 cooperates with the protrusion 73110 by lateral snapping when achieving the pressing effect on the protrusion 73110, it has high requirements on precision and has a certain risk of snap-fit failure. Therefore, in order to increase the difficulty of cooperation between the first pressure plate 41120 and the protrusion 73110, in some embodiments of the present invention, the first pressure plate 41120 is a bent plate with an open side expanded outward, so that the first pressure plate 41120 itself, or the recessed groove structure formed by the edge of the first pressure plate 41120 and the clamping block 41110, is a variable-section recessed structure with a larger spacing on the open side and a smaller spacing on the closed side. The first pressure plate 41120 with an open side expanded outward can provide a larger docking opening, thereby reducing the docking precision requirements of the protrusion 73110 on the fixing portion 7310, and reducing the difficulty of limiting the protrusion 73110 by the first pressure plate 41120.
[0084] Furthermore, in the material taking component 410 provided in the embodiment of the present invention, when the push-pull part 4120 is fixedly connected to the moving part 7320, it is also necessary to realize the connection from the circumferential direction of the moving part 7320. However, based on the structure of the third material 730, the push-pull part 4120 drives the moving part 7320 by applying an axial force to the moving part 7320. When the suction and filling resistance of the liquid sample is large, the push-pull part 4120 will have a certain risk of falling off in the smaller contact area with the moving part 7320. In some embodiments of the present invention, the push-pull portion 4120 includes a second pressure plate 41210. Specifically, the second pressure plate 41210 is fixed integrally with the push-pull portion 4120, and abuts against the end of the moving portion 7320 when the push-pull portion 4120 is fixed to the moving portion 7320. As a result, when the push-pull portion 4120 drives the moving portion 7320 to move, the push-pull portion 4120 can exert a force on the moving portion 7320 through the circumferential fixing effect and the surface contact effect of the end, thereby improving the driving stability of the push-pull portion 4120 on the moving portion 7320.
[0085] On the basis of the above structure, in order to reduce the structural complexity of the sample pre-processing mechanism, such as Figure 1 and Figure 2 As shown, the liquid separation mechanism 40 and the first material taking mechanism 10 are set as an integrated structure and transported synchronously, so as to avoid interference or movement obstruction problems between the two independently moving mechanisms. It should be noted that, on this basis, the lowest vertical operating height of the area of the first material taking mechanism 10 used to take the first material 710 is lower than the highest vertical operating height of the clamping part 4110; based on this, for the first material 710 that is arranged more densely and usually arranged in an array, when the first material taking mechanism 10 is taking, the clamping part 4110 can run to the highest operating height, and avoid collision and interference with the first material 710 due to the integrated structure, so as to ensure the smooth operation of the first material taking mechanism 10.
[0086] It should also be noted that when there is a risk of collision when the clamping part 4110 takes the third material 730, in the vertical direction, the lowest operating height of the clamping part 4110 can also be lower than the highest operating height of the first material taking mechanism 10 to meet the safety requirements for taking the third material 730.
[0087] Furthermore, in the sample pre-processing mechanism provided in the embodiment of the present invention, the liquid dispensing mechanism 40 specifically further includes a mounting frame 420 to support the second material 720. Specifically, the mounting frame 420 mainly includes a liquid receiving portion 4210 and a correction portion 4220, wherein the liquid receiving portion 4210 is used to limit and lock the second material 720 at the injection position so that the second material 720 remains in a stable state and can receive the injection of the liquid sample. The correction portion 4220 is used for calibration of the material taking component 410, specifically, calibration of the outlet position of the third material 730 taken from the material taking component 410. It should be noted that, since the injection position is limited by the liquid receiving part 4210, and the liquid receiving part 4210 and the correction part 4220 are both arranged on the mounting frame 420, when the mounting frame 420 remains stable, the liquid receiving part 4210 and the correction part 4220 can have a precise relative position, and before the material picking component 410 performs liquid injection, it can first calibrate the third material 730 clamped by the material picking component 410 based on the correction part 4220, so that the material picking component 410 has a more precise position relative to the liquid receiving part 4210 based on the mounting frame 420, and then the liquid separation component is accurately moved to the position of the liquid receiving part 4210 by driving it again.
[0088] Further, on the basis of the above embodiment, the correction part 4220 can be a closed rectangular frame structure, and the first sensor 42210 and the second sensor 42220 are respectively arranged on the two adjacent wall surfaces on the inner wall of the closed frame. It should be noted that the first sensor 42210 and the second sensor 42220 are linear sensors and the sensing paths of the two intersect. Taking the first sensor 42210 and the second sensor 42220 as laser sensors, the end for liquid injection on the third material 730 clamped in the material taking component 410 will first sense the first sensor 42210 and the second sensor 42220 when passing through the frame structure of the correction part 4220 and moving. The laser path of one of the sensors 220 is blocked. Taking the first sensor 42210 as an example, after the injection head moves to the laser path of the first sensor 42210, the first sensor 42210 is blocked and feedback is given to the driving component of the injection head. The driving component further drives the injection head to move along the direction of the laser path of the first sensor 42210 until it reaches the intersection of the laser paths of the first sensor 42210 and the second sensor 42220. At this time, the laser path of the second sensor 42220 is also blocked, and the injection head is adjusted into place. This adjustment method can avoid rigid collision and realize calibration of the material picking component 410, thereby reducing the risk of damage to the third material 730.
[0089] Further, in the sample pre-processing mechanism provided in the embodiment of the present invention, the liquid receiving part 4210 specifically includes a support platform 42110 and a locking part 42120 disposed on the support platform 42110. Specifically, the locking part 42120 is used to clamp and fix the second material 720 in the circumferential direction of the second material 720, and in some embodiments, the locking part 42120 includes two sections in its axial direction, namely, a partial opening structure and a partial closed annular structure, and the second material 720 can be inserted into the locking part 42120 and clamped through the area of the opening structure. The support platform 42110 is used to carry the locking part 42120, and the support platform 42110 can be stably located at the injection position, and combined with the locking part 42120, the second material 720 can be accurately positioned, thereby keeping the second material 720 fixed at the injection position.
[0090] And based on the above embodiment, considering the transportation demand of the second material 720, such as Figure 9-11 As shown, the liquid receiving portion 4210 also includes a fixed seat 42130, which is a fixedly arranged bearing structure, and a slideway 42140 structure is provided on the fixed seat 42130, and the support platform 42110 is slidably arranged on the slideway 42140 so as to be able to move under the guide path of the slideway 42140; it should be noted that the support platform 42110 can be provided with a protrusion 73110 or a pulley and other structures to slide with the slideway 42140, and at the same time, it is driven by a motor or a cylinder, etc., and its conventional sliding and driving cooperation is no longer repeated here. In particular, the guide path of the slide 42140 passes through the injection position, and the support platform 42110 can pass through the injection position during the operation along the slide 42140. At the same time, the support platform 42110 is limited by the fixed seat 42130 at the injection position, which can be achieved by setting a raised locking portion 42120. Similarly, in some embodiments of the present invention, the support platform 42110 is located at one side end of the slide 42140 when in the injection position, and the limitation is achieved by the path end of the slide 42140.
[0091] It should be noted that the arrangement of the fixed seat 42130 and the slide 42140 enhances the degree of freedom in the arrangement of the second material 720. The second material 720 can be arranged at any position on the guide path of the slide 42140. The second material 720 is clamped by the locking portion 42120 on the guide path of the slide 42140, and can reach the liquid injection position through the sliding action of the support platform 42110 to realize the subsequent liquid sample injection of the liquid separation portion.
[0092] Furthermore, in some embodiments of the present invention, the second material taking mechanism 30 further includes a cover opening portion 310, and correspondingly, the fixed seat 42130 is further provided with an opening and closing position for opening or closing the cover of the second material 720, and the opening and closing position is provided on the guide path of the slide 42140, so that the support platform 42110 can drive the locking portion 42120 to move to the opening and closing position on the slide 42140 during the sliding process along the slide 42140. At the same time, the cover opening portion 310 is used to transport, open and close the cover of the second material 720. Since the second material 720 needs to maintain its cleanliness, the second material 720 is a bottle-shaped structure with a cover body, and the cover opening part 310 is used to clamp the cover area of the second material 720 to drive the second material 720 to move; the cover opening part 310 moves the second material 720 to the opening and closing position to place the second material 720 above the support platform 42110 located at the opening and closing position. After the support platform 42110 clamps the second material 720 through the locking part 42120, the main structure of the second material 720 remains stationary, and at this time the cover opening part 310 can realize the opening action of the second material 720 by rotating.
[0093] It should be noted that in the above structure, by setting the movement path of the support platform 42110, the second material 720 in other areas can be moved to the opening and closing position on the slide 42140 through the opening cover part 310, and the locking part 42120 located at the opening and closing position clamps the main body of the second material 720, and then the opening cover part 310 realizes the unscrewing of the cover of the second material 720 through the rotation action; and the opened second material 720 is carried by the support platform 42110 and moves along the slide 42140 to the liquid injection position, and receives the liquid sample added by the material taking component 410. After the second material 720 completes receiving the liquid sample, the support platform 42110 carries the second material 720 back to the open and closed position. At this time, the cover body temporarily stored in the open cover part 310 is locked with the second material 720 through the rotation of the open cover part 310. The locking part 42120 is released and the open cover part 310 drives the second material 720 to move to other placement positions, thereby completing a single cycle of the second material 720.
[0094] In order to improve the efficiency of the sample packaging process, in some embodiments of the present invention, multiple groups of slideways 42140 are arranged at intervals so that multiple groups of second materials 720 can be packaged simultaneously. It should be noted that the specifications of the locking parts 42120 carried by the support platforms 42110 in the multiple groups of slideways 42140 can be the same to improve the packaging efficiency of the second materials 720 of the same specifications; at the same time, the specifications of the locking parts 42120 can also be different to adapt to the second materials 720 of different specifications.
[0095] It should be noted that, preferably, each group of slides 42140 is arranged in parallel to make the structure of the fixed seat 42130 more regular, and at the same time, the lengths of the slides 42140 are equal, so that the injection positions on multiple groups of slides 42140 are located on the same straight line, and the material picking component 410 calibrated by the correction part 4220 has the same moving direction during the process of moving toward the injection positions on different slides 42140, thereby reducing the error of the material picking component 410 moving toward different injection positions.
[0096] In order to further optimize the above technical solution, each set of slideways 42140 is correspondingly provided with at least one in-place sensor 42150 and a liquid level sensor to improve the stability of the working process of the liquid dispensing mechanism 40. Specifically, the in-place sensor 42150 is used to detect that the second material 720 at the injection position has moved into position, and preferably the detection range of the in-place sensor 42150 includes the top opening position of the second material 720 to detect the opening state of the second material 720. The in-place sensor 42150 is connected to the drive assembly for communication, and when the in-place sensor 42150 detects that the second material 720 does not exist at the corresponding injection position, that is, the supply of the second material 720 fails, or the cover of the second material 720 at the corresponding injection position is not screwed down, it will feedback to the drive assembly to stop running, thereby avoiding injection failure.
[0097] At the same time, the liquid level sensor is used to detect the bottle body of the second material 720 to detect the filling level in the second material 720 located at the filling position. The liquid level sensor is also communicated with the drive component to feedback the drive component to stop moving and the material taking component 410 to stop filling after detecting that the liquid sample corresponding to the second material 720 is filled to the preset liquid level to prevent the liquid sample from overflowing from the second material 720.
[0098] In addition, it should be noted that, based on the above-mentioned embodiment, the in-place sensor 42150 can be set horizontally or tilted to realize the detection of the second material 720; and at the same time, it should be noted that at least one group of slides 42140 corresponding to the in-place sensor 42150 is set tilted, and the slide 42140 is adapted to two or more second materials 720 with the same outer diameter but different heights, so that the slide 42140 is more versatile and can meet the use of two or more specifications of second materials 720, thereby reducing the cost of the fixed seat 42130.
[0099] It should also be noted that, in the sample preprocessing mechanism provided in the embodiment of the present invention, the track bracket used for the first material picking mechanism 10, the second material picking mechanism 30, and the liquid dispensing mechanism 40 to realize position transfer can be set according to the movement requirements under actual working conditions. Usually, the guide area of the track bracket is set at least along three directions perpendicular to each other, that is, with the horizontal plane as the reference plane, the setting direction of the track bracket needs to be set along the X direction, the Y direction and the Z direction, and the setting length in each direction is set according to the setting area of the first material 710, the second material 720 and the third material 730, so as to meet the need to be able to take various materials.
[0100] Furthermore, in the sample preprocessing mechanism provided in the embodiment of the present aspect, the second placement rack 620 may be provided with a plurality of tray racks, a single tray rack being used to place a plurality of second materials 720, and the tray rack having a handle for grabbing and clamping, and the second material picking mechanism 30 may be provided with a plurality of groups for clamping and opening the plurality of second materials 720 at the same time, and the second material picking mechanism 30 may be capable of clamping the tray rack so as to clamp and transport the plurality of second materials 720 at the same time by clamping the tray rack; for the second material 720 that has been packaged, the second material picking mechanism 30 may realize the rapid transportation of the second material 720 by clamping the tray rack. On this basis, the sample pre-processing mechanism also includes an automatic guided clamping mechanism (AGV), which is arranged at the downstream position of the second material picking mechanism 30 and has clamping structures of various specifications to clamp the second material 720 of different specifications in the tray rack; the tray rack clamped by the second material picking mechanism 30 can be placed on a transmission belt or chain to be transferred to the AGV station, and the AGV is used to clamp and subsequently package the tray rack.
[0101] In the present application, the terms "upper", "lower", "left", "right", "front", "back", "top", "bottom", "inside", "outside", "middle", "vertical", "horizontal", "lateral", "longitudinal" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings. These terms are mainly for better describing the present application and its embodiments, and are not used to limit the indicated devices, elements or components to have a specific orientation, or to be constructed and operated in a specific orientation; in addition, the terms "installed", "set", "provided with", "connected", "connected", and "socketed" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection, or an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, or it can be an internal connection between two devices, elements or components. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to the specific circumstances.
[0102] The above description is only a preferred embodiment of the present invention and an explanation of the technical principles used, and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. The scope of the invention involved in the present invention is not limited to the technical solution formed by a specific combination of the above-mentioned technical features, but also should cover other technical solutions formed by any combination of the above-mentioned technical features or their equivalent features without departing from the above-mentioned inventive concept. For example, the above-mentioned features are replaced with the technical features with similar functions disclosed in the present invention (but not limited to) to form a technical solution.
Claims
1. A sample pre-processing mechanism, characterized in that: include: a first material taking mechanism (10) and a cover opening and closing mechanism (20), wherein the first material taking mechanism (10) is used to carry a first material (710) to a cover opening position, and the cover opening and closing mechanism (20) opens the cover of the first material (710) at the cover opening position, and the first material (710) is used to contain a liquid sample; A second material taking mechanism (30) is used to transport a second material (720) to a liquid injection position, wherein the second material (720) is a filling bottle for filling the liquid sample; The liquid dispensing mechanism (40) is used to dispense the liquid sample in the first material (710) into the second material (720), and comprises a material taking component (410) and a driving component. The material taking component (410) is used to take a third material (730), and the third material (730) has an open cavity with a variable volume. The driving component is used to drive the cavity of the third material (730) to change so as to achieve the suction and discharge of the liquid sample by the third material (730); the operating position of the material taking component (410) at least passes through the cover opening position and the liquid injection position.
2. The sample pre-processing mechanism according to claim 1, characterized in that: The invention comprises a first placement rack (610) and a second placement rack (620) which are arranged at intervals, wherein the first placement rack (610) is used to place a plurality of the first materials (710), and the second placement rack (620) is used to place a plurality of the second materials (720); the cover opening position and the liquid injection position are both located between the first placement rack (610) and the second placement rack (620); and the liquid separation mechanism (40) is arranged between the first placement rack (610) and the second placement rack (620).
3. The sample pre-processing mechanism according to claim 1, characterized in that: The cover opening and closing mechanism (20) comprises a first cover opening component (210) and a second cover opening component (220); the first cover opening component (210) comprises a pressing unit (2110) and a cover opening unit (2120); the pressing unit (2110) is used to limit the first material (710) in a first direction; and the cover opening unit (2120) is used to remove the first cover (7110) on the first material (710) when the first material (710) is limited by the pressing unit (2110); The second cover opening assembly (220) comprises a clamping unit (2210) and a pressure rod unit (2220), wherein the pressure rod unit (2220) is slidably arranged in the first direction to apply a force to the center of the second cover body (7120) of the first material (710), and drives the outer wall of the second cover body (7120) to expand to unlock the first material (710), and the clamping unit (2210) is used to clamp the second cover body (7120) from the circumferential direction.
4. The sample pre-processing mechanism according to claim 3, characterized in that: The switch cover mechanism (20) further comprises a push rod unit, wherein the push rod unit is fixedly arranged on the clamping unit (2110), and the push rod unit and the pressure rod unit (2220) are spaced apart in the first direction, and the push rod unit is used to apply a force in the first direction to the second cover body (7120) in a direction opposite to that of the pressure rod unit (2220) to drive the outer wall of the second cover body (7120) to contract.
5. The sample pre-processing mechanism according to claim 3, characterized in that: The cover opening unit (2120) comprises a plurality of load-bearing claws (21210) uniformly arranged along the circumferential direction, and a second driving part drivingly connected to the load-bearing claws (21210), wherein the second driving part is used to drive the load-bearing claws (21210) to move toward and away from the center of a circle; each load-bearing claw (21210) is provided with a clamping claw (21230) floatingly arranged on one side facing the center of the circle via at least two elastic members (21220), and the clamping claw (21230) is used to clamp and lock the first cover body (7110) in the first direction.
6. The sample pre-processing mechanism according to claim 5, characterized in that: The pressing unit (2110) comprises a pressing plate (21110) and a third driving part, wherein the third driving part is used to drive the pressing plate (21110) to move along the first direction, and a through hole (21120) having a size larger than that of the first cover body (7110) is provided in the middle area of the pressing plate (21110), and the pressing plate (21110) abuts against and presses the first material (710) along the circumferential outer side of the first cover body (7110).
7. The sample pre-processing mechanism according to claim 3, characterized in that: The device further comprises a transfer assembly (50), wherein the transfer assembly (50) comprises a support portion (510) for carrying the first material (710), and a fourth drive portion drivingly connected to the support portion (510); the fourth drive portion is used to drive the support portion (510) to switch between the first workstation and the second workstation; The first cover opening component (210) performs a cover opening action on the first cover body (7110) of the first material (710) at the first station, and the second cover opening component (220) performs a cover opening action on the second cover body (7120) of the first material (710) at the second station. The first station and the second station are arranged along a second direction, and the second direction is perpendicular to the first direction.
8. The sample pre-processing mechanism according to claim 1, characterized in that: The material taking component (410) comprises a support seat, and a clamping portion (4110) and a push-pull portion (4120) arranged on the support seat, and the driving component drives the push-pull portion (4120) to slide relative to the clamping portion (4110) to move toward and away from the clamping portion (4110); The third material (730) includes a fixed part (7310) and a moving part (7320) which are arranged to slide relative to each other, a cavity is formed between the fixed part (7310) and the moving part (7320), and one end of the fixed part (7310) is provided with an opening connected to the cavity, and the moving part (7320) moves relatively in the fixed part (7310) to change the size of the cavity; the clamping part (4110) is used to fix the fixed part (7310), and the push-pull part (4120) is used to fix the moving part (7320).
9. The sample pre-processing mechanism according to claim 8, characterized in that: The push-pull portion (4120) and the end portion of the moving portion (7320) are circumferentially clamped and fixed, and the push-pull portion (4120) includes a second pressure plate (41210), which abuts against the end portion of the moving portion (7320) when the push-pull portion (4120) and the moving portion (7320) are fixed.
10. The sample pre-processing mechanism according to claim 1, characterized in that: The liquid dispensing mechanism (40) further comprises a mounting frame (420), wherein the mounting frame (420) comprises a liquid receiving portion (4210) and a correction portion (4220), wherein the liquid receiving portion (4210) is used to limit the second material (720) to the liquid injection position; the correction portion (4220) and the liquid injection position are fixed in relative positions on the mounting frame (420), and after the position of the material taking component (410) is calibrated by the correction portion (4220), the liquid sample is added into the second material (720) at the liquid injection position.
11. The sample pre-processing mechanism according to claim 10, characterized in that: The correction part (4220) is a closed frame structure and a first sensor (42210) and a second sensor (42220) are arranged on the inner wall of the frame; the first sensor (42210) and the second sensor (42220) are linear sensors and their sensing paths intersect; the outer diameter of the injection tip calibrated on the material picking component (410) is smaller than the closed frame and is calibrated at the intersection of the first sensor (42210) and the second sensor (42220); the sensing paths of the first sensor (42210) and the second sensor (42220) are perpendicular.
12. The sample pre-processing mechanism according to claim 10, characterized in that: The liquid receiving portion (4210) includes a support platform (42110) and a locking portion (42120) disposed on the support platform (42110), wherein the support platform (42110) can pass through the injection position, and the locking portion (42120) is used to clamp the second material (720) in the circumferential direction of the second material (720) and can limit the second material (720) to the injection position.
13. The sample pre-processing mechanism according to claim 12, characterized in that: The liquid receiving portion (4210) further comprises a fixed seat (42130), a slideway (42140) is provided on the fixed seat (42130), the support platform (42110) is slidably arranged on the slideway (42140) and passes through the liquid injection position, and the support platform (42110) is limited by the fixed seat (42130) at the liquid injection position.
14. The sample pre-processing mechanism according to claim 13, characterized in that: The second material picking mechanism (30) also includes a cover opening portion (310), and the support platform (42110) also passes through an opening and closing position on the guide path of the slide (42140). The second material picking mechanism (30) is used to transport the second material (720) to the opening and closing position, and to open the cover of the second material (720) through the cover opening portion (310) after the locking portion (42120) locks the second material (720).
15. The sample pre-processing mechanism according to claim 13, characterized in that: Any group of the slideways (42140) is correspondingly provided with at least one pair of in-place sensors (42150) and liquid level sensors, wherein the in-place sensors (42150) are used to detect that the second material (720) at the injection position has moved into position, and the liquid level sensor is used to detect the injection liquid level in the second material (720).
16. The sample pre-processing mechanism according to claim 2, characterized in that: The second placement rack (620) is provided with a plurality of tray racks, and a single tray rack is used to accommodate a plurality of the second materials (720); the second material picking mechanism (30) is provided with a plurality of groups to clamp and open the plurality of the second materials (720) at the same time, and the second material picking mechanism (30) can clamp and transfer the plurality of the second materials (720) at the same time by clamping the tray rack.
Citation Information
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