Magnetic resonance transverse relaxation time determination method and system

Abstract

The invention relates to a magnetic resonance transverse relaxation time measuring method and system. The method comprises the following steps: acquiring magnetic resonance signals at at least two echo moments; the magnetic resonance signal is acquired under the condition that a spin echo sequence is applied to a region of interest of an acquisition object according to a preset ratio relationship; the ratio relation represents a time ratio of at least two echo moments; any two echo moments comprise a first echo moment and a second echo moment; determining a transverse relaxation time measurement result of any two echo moments according to a ratio relation of the at least two echo moments, the first echo moment and the magnetic resonance signal; and determining a magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results of any two echo moments. By adopting the method, the time required by the signal detection and fitting process can be reduced, and the measurement efficiency of the transverse relaxation time is improved.

Description

Technical Field

[0001] The present application relates to the field of magnetic resonance scanning technology, and in particular to a method and system for measuring magnetic resonance transverse relaxation time. Background Art

[0002] In magnetic resonance imaging, the relaxation time of protons has an important influence on image quality and signal intensity. The relaxation time includes longitudinal relaxation time and transverse relaxation time.

[0003] Taking the measurement process of transverse relaxation time as an example, in the related technology, the magnetization vector is flipped from the longitudinal plane to the transverse plane using a spin echo sequence, and then multiple sets of magnetic resonance signals at different echo times are collected. The measurement result of the transverse relaxation time is obtained by fitting the collected magnetic resonance data.

[0004] However, the signal detection and fitting process in the related art method requires a lot of time, resulting in low efficiency in determining the transverse relaxation time. Summary of the invention

[0005] Based on this, it is necessary to provide a method and system for measuring the transverse relaxation time of magnetic resonance in order to solve the above-mentioned technical problems, so as to reduce the time required for signal detection and fitting process and improve the measurement efficiency of the transverse relaxation time.

[0006] In a first aspect, the present application provides a method for determining magnetic resonance transverse relaxation time, comprising:

[0007] Acquire magnetic resonance signals at at least two echo moments; the magnetic resonance signals are acquired by applying a spin echo sequence to a region of interest of an acquisition object according to a preset ratio relationship; the ratio relationship represents a time ratio of at least two echo moments; any two echo moments include a first echo moment and a second echo moment;

[0008] Determine the transverse relaxation time measurement results of any two echo moments according to the ratio relationship between at least two echo moments, the first echo moment and the magnetic resonance signal;

[0009] Based on the transverse relaxation time measurement results at any two echo times, a magnetic resonance transverse relaxation time measurement result is determined.

[0010] In one embodiment, determining the transverse relaxation time measurement results of any two echo moments according to the ratio relationship between at least two echo moments, the first echo moment and the magnetic resonance signal comprises:

[0011] For any two echo moments, according to the magnetic resonance signal at the two echo moments, the functional relationship between the transverse relaxation time and the magnetic resonance signal, the ratio of the magnetic resonance signals at the two echo moments is obtained;

[0012] The transverse relaxation time measurement results at the two echo moments are determined according to the ratio relationship between the two echo moments and the ratio of the magnetic resonance signals at the first echo moment and the two echo moments.

[0013] In one embodiment, obtaining the ratio of the magnetic resonance signals at two echo times according to the functional relationship between the magnetic resonance signals at two echo times, the transverse relaxation time and the magnetic resonance signals includes:

[0014] Substituting the ratio of the magnetic resonance signals at the two echo times into the functional relationship between the transverse relaxation time and the magnetic resonance signal, respectively, to obtain a first functional relationship and a second functional relationship;

[0015] The ratio of the magnetic resonance signals at two echo times is determined according to the ratio of the first functional relationship to the second functional relationship.

[0016] In one embodiment, determining the transverse relaxation time measurement results at the two echo moments according to the ratio relationship between the two echo moments and the ratio of the magnetic resonance signals at the first echo moment and the two echo moments includes:

[0017] Calculate the product of the ratio relationship between the two echo moments and the first echo moment to obtain the product result;

[0018] The ratio of the product result to the logarithm of the ratio of the magnetic resonance signals at the two echo times is obtained, and the negative number of the ratio is used as the transverse relaxation time measurement result at the two echo times.

[0019] In one embodiment, determining the magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results at any two echo moments includes:

[0020] In a case where the at least two echo time points include two echo time points, taking the transverse relaxation time measurement results of the two echo time points as the magnetic resonance transverse relaxation time measurement results;

[0021] When the at least two echo times include three or more echo times, an average value of the transverse relaxation time measurement results of the at least two echo times is used as the magnetic resonance transverse relaxation time measurement result.

[0022] In a second aspect, the present application also provides a magnetic resonance transverse relaxation time determination system, the magnetic resonance transverse relaxation time determination system comprising a magnetic resonance device and a computer device;

[0023] A magnetic resonance device, used for acquiring magnetic resonance signals at at least two echo moments according to a preset ratio relationship when a spin echo sequence is applied to a region of interest of an acquisition object; the ratio relationship represents a time ratio of at least two echo moments; any two echo moments include a first echo moment and a second echo moment;

[0024] The computer device is used to determine the transverse relaxation time measurement results of any two echo moments according to the ratio relationship between at least two echo moments, the first echo moment and the magnetic resonance signal; based on the transverse relaxation time measurement results of any two echo moments, determine the magnetic resonance transverse relaxation time measurement result.

[0025] In a third aspect, the present application also provides a magnetic resonance transverse relaxation time measuring device, comprising:

[0026] An acquisition module is used to acquire magnetic resonance signals at at least two echo moments; the magnetic resonance signals are acquired by applying a spin echo sequence to a region of interest of an acquisition object according to a preset ratio relationship; the ratio relationship represents a time ratio of at least two echo moments; any two echo moments include a first echo moment and a second echo moment;

[0027] A first determination module is used to determine the transverse relaxation time measurement results of any two echo moments according to the ratio relationship between at least two echo moments, the first echo moment and the magnetic resonance signal;

[0028] The second determination module is used to determine the magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results at any two echo moments.

[0029] In a fourth aspect, the present application further provides a computer device, comprising a memory and a processor, wherein the memory stores a computer program, and when the processor executes the computer program, the content of any one embodiment of the method for measuring the magnetic resonance transverse relaxation time in the first aspect is implemented.

[0030] In a fifth aspect, the present application further provides a computer-readable storage medium having a computer program stored thereon, which, when executed by a processor, implements the content of any one embodiment of the method for measuring the magnetic resonance transverse relaxation time in the first aspect.

[0031] In a sixth aspect, the present application further provides a computer program product, comprising a computer program, which, when executed by a processor, implements the content of any one embodiment of the method for measuring magnetic resonance transverse relaxation time in the first aspect.

[0032] The above-mentioned magnetic resonance transverse relaxation time determination method and system obtain magnetic resonance signals at at least two echo moments; the magnetic resonance signals are collected under the condition of applying a spin echo sequence to the region of interest of the acquisition object according to a preset ratio relationship; the ratio relationship represents the time ratio of at least two echo moments; any two echo moments include the first echo moment and the second echo moment; according to the ratio relationship of at least two echo moments, the first echo moment and the magnetic resonance signal, the transverse relaxation time determination results of any two echo moments are determined; based on the transverse relaxation time determination results of any two echo moments, the magnetic resonance transverse relaxation time determination results are determined. This method calculates the transverse relaxation time by a numerical calculation method when collecting at least two groups of magnetic resonance signals, greatly shortens the acquisition and calculation time in the process of measuring the magnetic resonance transverse relaxation time from the perspectives of signal acquisition and calculation process, and improves the efficiency of measuring the transverse relaxation time. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] In order to more clearly illustrate the technical solutions in the embodiments of the present application or related technologies, the drawings required for use in the embodiments of the present application or related technical descriptions will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0034] Figure 1 A diagram showing an application environment of a method for measuring magnetic resonance transverse relaxation time in one embodiment;

[0035] Figure 2 Schematic diagram of a method for measuring magnetic resonance transverse relaxation time in one embodiment;

[0036] Figure 3 is a schematic diagram of a decay curve of a magnetic resonance signal over time in one embodiment;

[0037] Figure 4 Schematic diagram of a method for measuring magnetic resonance transverse relaxation time in one embodiment;

[0038] Figure 5 Schematic diagram of a method for measuring magnetic resonance transverse relaxation time in one embodiment;

[0039] Figure 6 Schematic diagram of a method for measuring magnetic resonance transverse relaxation time in one embodiment;

[0040] Figure 7 Schematic diagram of a method for measuring magnetic resonance transverse relaxation time in one embodiment;

[0041] Figure 8Schematic diagram of a method for measuring magnetic resonance transverse relaxation time in one embodiment;

[0042] Fig. 9 is a structural block diagram of a magnetic resonance transverse relaxation time measuring device in one embodiment;

[0043] Fig.10 FIG. 4 is a diagram showing the internal structure of a computer device in one embodiment. DETAILED DESCRIPTION

[0044] In order to make the purpose, technical solution and advantages of the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0045] Before introducing the technical solution of the present application in detail, a brief introduction to the background technology of the present application is first given.

[0046] In magnetic resonance imaging, taking the measurement process of transverse relaxation time as an example, in related technologies, the transverse relaxation time measurement result is obtained by fitting by collecting magnetic resonance data with different echo times after the spin echo sequence is flipped from the longitudinal plane to the transverse plane. During the acquisition process, at least 4 sets of magnetic resonance data with different echo times are usually collected. In order to obtain more accurate transverse relaxation time measurement results, it is often necessary to collect 10 sets of magnetic resonance data with different echo times. In the fitting process, it is often a process of continuously iterating to obtain the minimum error. The time value required for the fitting process is related to factors such as the initial value, the fitting model, and the hardware performance.

[0047] It can be seen that in the process of determining the transverse relaxation time measurement results of the related technology, both the data acquisition process and the fitting process require a lot of time, resulting in a low efficiency in the measurement of the transverse relaxation time.

[0048] In view of the above problems, the present application provides a method and system for determining the transverse relaxation time of magnetic resonance. When collecting at least two groups of magnetic resonance signals, the transverse relaxation time is calculated by a numerical calculation method. From the perspectives of signal acquisition and calculation process, the acquisition and calculation time in the process of determining the transverse relaxation time of magnetic resonance is greatly shortened, and the efficiency of determining the transverse relaxation time is improved. Of course, the technical solution provided in the embodiments of the present application is not limited to solving only the above problems, and there are other technical effects, which can be specifically described in the following embodiments. Next, the technical solution of the present application is described in detail.

[0049] The magnetic resonance transverse relaxation time determination method provided in the embodiment of the present application can be applied to Figure 1In the application environment shown. The application environment includes a computer device 101 and a magnetic resonance device 102, and the computer device 101 and the magnetic resonance device 102 communicate with each other. The magnetic resonance device 102 is used to collect magnetic resonance signals under the condition of applying a spin echo sequence to the region of interest of the acquisition object according to a preset ratio relationship. The computer device 101 is used to obtain magnetic resonance signals at at least two echo moments; any two echo moments include a first echo moment and a second echo moment; according to the ratio relationship of at least two echo moments, the first echo moment and the magnetic resonance signal, the transverse relaxation time measurement result of any two echo moments is determined; based on the transverse relaxation time measurement result of any two echo moments, the magnetic resonance transverse relaxation time measurement result is determined.

[0050] In an exemplary embodiment, Figure 2 As shown, a method for determining magnetic resonance transverse relaxation time is provided, and the method is applied to Figure 1 The computer device in the example is used to illustrate, including the following steps 201 to 203. Among them:

[0051] S201, acquiring magnetic resonance signals at at least two echo moments; the magnetic resonance signals are acquired by applying a spin echo sequence to a region of interest of an acquisition object according to a preset ratio relationship; the ratio relationship represents a time ratio of at least two echo moments; any two echo moments include a first echo moment and a second echo moment.

[0052] Among them, at least two echo moments refer to at least two moments after the magnetic resonance device applies a spin echo sequence to the region of interest of the acquisition object, and there is a corresponding ratio relationship between the at least two echo moments. The ratio relationship can be set in advance by the user, or it can be determined according to the historical time ratio. The embodiment of the present application does not limit the ratio relationship of at least two echo moments. For example, the time ratio of at least two echo moments is 1 / 2, and the number of at least two echo moments is 3, then the three echo moments can be the 2nd second, the 4th second and the 6th second respectively. Any two echo moments under the at least two echo moments include the first echo moment and the second echo moment.

[0053] In an embodiment of the present application, the computer device may send a magnetic resonance transverse relaxation time determination instruction generated based on the user's needs to the magnetic resonance device. The magnetic resonance transverse relaxation time determination instruction carries a magnetic resonance signal collected at least two echo moments after applying the spin echo sequence. Then, after applying the spin echo sequence to the region of interest of the acquisition object, the magnetic resonance device may collect the magnetic resonance signal of the region of interest of the acquisition object according to a preset ratio relationship, and send the collected magnetic resonance signals at at least two echo moments to the computer device. Optionally, the magnetic resonance signals at at least two echo moments collected by the magnetic resonance device after applying the spin echo sequence are stored in a magnetic resonance signal memory of the magnetic resonance device. The computer device may send a signal acquisition instruction to the magnetic resonance device, and when the magnetic resonance device receives the signal acquisition instruction, the magnetic resonance signals at at least two echo moments in the magnetic resonance signal memory that match the signal acquisition instruction are sent to the computer device. The embodiment of the present application does not limit the method of acquiring the magnetic resonance signals at at least two echo moments.

[0054] Exemplarily, assuming that the number of at least two echo moments is 2, then the two echo moments can be the first echo moment TE1 and the second echo moment TE2, respectively, and the two echo moments satisfy TE2=2TE1, and the amplitude images corresponding to the magnetic resonance signals acquired by the corresponding imaging sequence are Im(TE1) and Im(TE2), respectively.

[0055] S202, determining transverse relaxation time measurement results of any two echo moments according to a ratio relationship between at least two echo moments, the first echo moment and the magnetic resonance signal.

[0056] In the embodiment of the present application, after the magnetic resonance device applies a spin echo sequence to the region of interest of the acquisition object, the longitudinal plane is flipped to the transverse plane so that the magnetic resonance signal can be detected by the magnetic resonance device, and the magnetic resonance signal is acquired at two echo times TE. The magnetic resonance signal and the echo time satisfy the following relationship:

[0057]

[0058] Wherein, T2 represents the transverse relaxation time; represents the magnetic resonance signal collected at the TE moment; M represents the strength of the longitudinal magnetization vector in the equilibrium state, that is, the strength of the magnetization vector just flipped to the transverse plane after the spin echo sequence is applied.

[0059] Figure 3 It is a schematic diagram of the attenuation curve of the magnetic resonance signal over time. It can be seen from the figure that with the change of the echo time, the magnetic resonance signal gradually decreases from M to 0.

[0060] After obtaining the magnetic resonance signals at at least two echo moments, for any two echo moments, the computer device can substitute the ratio relationship of the two echo moments, the first echo moment and the magnetic resonance signal into a preset transverse relaxation time determination model, and use the transverse relaxation time determination model to analyze the ratio relationship of the two echo moments and the magnetic resonance signal to obtain the transverse relaxation time determination results of the two echo moments. Alternatively, the computer device can also perform a dot division on the magnetic resonance signals at the two echo moments, substitute the ratio relationship of the two echo moments into the dot division result, and determine the transverse relaxation time determination results of the two echo moments by numerical calculation.

[0061] S203, determining a magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results at any two echo moments.

[0062] In an embodiment of the present application, it is assumed that the number of echo moments is 2, and the corresponding transverse relaxation time measurement result is 1. Then, the computer device can use the transverse relaxation time measurement results of two echo moments as the magnetic resonance transverse relaxation time measurement result. Assuming that the number of echo moments is 3 or more than 3, the corresponding transverse relaxation time measurement results are 2 or more than 2. Then, the computer device can calculate the average value of at least two transverse relaxation time measurement results, and use the obtained average value as the magnetic resonance transverse relaxation time measurement result. Alternatively, the computer device can also filter out the maximum transverse relaxation time measurement result from at least two transverse relaxation time measurement results, and use the maximum transverse relaxation time measurement result as the magnetic resonance transverse relaxation time measurement result. The embodiment of the present application does not limit the method of determining the magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results of any two echo moments.

[0063] In the above-mentioned magnetic resonance transverse relaxation time determination method, magnetic resonance signals at at least two echo moments are obtained; the magnetic resonance signals are collected under the condition of applying a spin echo sequence to the region of interest of the acquisition object according to a preset ratio relationship; the ratio relationship represents the time ratio of at least two echo moments; any two echo moments include the first echo moment and the second echo moment; according to the ratio relationship of at least two echo moments, the first echo moment and the magnetic resonance signal, the transverse relaxation time determination results of any two echo moments are determined; based on the transverse relaxation time determination results of any two echo moments, the magnetic resonance transverse relaxation time determination results are determined. In the case of collecting at least two groups of magnetic resonance signals, the method calculates the transverse relaxation time by a numerical calculation method, greatly shortens the acquisition and calculation time in the process of measuring the magnetic resonance transverse relaxation time from the two perspectives of signal acquisition and calculation process, and improves the efficiency of transverse relaxation time determination.

[0064] The magnetic resonance transverse relaxation time measurement result is composed of the transverse relaxation time measurement results corresponding to any two echo moments. Then, the specific content of determining the transverse relaxation time measurement result of any two echo moments according to the ratio relationship of at least two echo moments, the first echo moment and the magnetic resonance signal is introduced through an embodiment. Figure 4 As shown, the specific content includes the following steps:

[0065] S301 , for any two echo moments, according to a functional relationship between the magnetic resonance signals at the two echo moments and the transverse relaxation time and the magnetic resonance signals, obtain a ratio of the magnetic resonance signals at the two echo moments.

[0066] The functional relationship between the transverse relaxation time and the magnetic resonance signal may refer to the relevant formula in S202.

[0067] In an embodiment of the present application, the computer device can substitute the magnetic resonance signals at the two echo moments and the corresponding echo moments into the functional relationship respectively, and obtain the functional relationship at the first echo moment and the functional relationship at the second echo moment. And after dot division of the functional relationship at the first echo moment and the functional relationship at the second echo moment, the ratio of the magnetic resonance signals at the two echo moments is obtained. Alternatively, the computer device can also first calculate the ratio of the functional relationship between the two transverse relaxation times and the magnetic resonance signals, and then substitute the magnetic resonance signals at the two echo moments and the corresponding echo moments into the ratio of the functional relationship, and obtain the ratio of the magnetic resonance signals at the two echo moments.

[0068] In one embodiment, Figure 5 As shown, the specific contents of obtaining the ratio of the magnetic resonance signals at two echo times according to the functional relationship between the magnetic resonance signals at two echo times, the transverse relaxation time and the magnetic resonance signals include:

[0069] S401 , respectively substitute the ratio of the magnetic resonance signals at two echo times into the functional relationship between the transverse relaxation time and the magnetic resonance signal to obtain a first functional relationship and a second functional relationship.

[0070] In the embodiment of the present application, for any two echo moments, the computer device can substitute the magnetic resonance signals at the two echo moments into the functional relationship between the transverse relaxation time and the magnetic resonance signal, respectively, to obtain a first functional relationship and a second functional relationship. The first functional relationship can be expressed as: ; The second functional relationship can be expressed as: .

[0071] S402, determining a ratio of magnetic resonance signals at two echo times according to a ratio of the first functional relationship to the second functional relationship.

[0072] In one embodiment, the specific content of determining the ratio of magnetic resonance signals at two echo moments according to the ratio of the first functional relationship and the second functional relationship is introduced, and the specific content includes:

[0073] The ratio of the first functional relationship to the second functional relationship is calculated, and the ratio is used as the ratio of magnetic resonance signals at two echo time points.

[0074] In the embodiment of the present application, the computer device can calculate the ratio of the two functional relationships to obtain the ratio of the magnetic resonance signals at the two echo times. The ratio of the magnetic resonance signals at the two echo times can be expressed as:

[0075]

[0076] S302, determining transverse relaxation time measurement results at the two echo moments according to the ratio relationship between the two echo moments and the ratio of the magnetic resonance signals at the first echo moment and the two echo moments.

[0077] In an embodiment of the present application, after obtaining the magnetic resonance signal ratio at two echo moments, the computer device can substitute the ratio relationship between the two echo moments and the first echo moment into the magnetic resonance signal ratio, and calculate the transverse relaxation time measurement results of the two echo moments based on the ratio relationship.

[0078] In the above-mentioned method for measuring the transverse relaxation time of magnetic resonance, for any two echo moments, according to the magnetic resonance signals at the two echo moments, the functional relationship between the transverse relaxation time and the magnetic resonance signals, the ratio of the magnetic resonance signals at the two echo moments is obtained; according to the ratio relationship between the two echo moments, the ratio of the magnetic resonance signals at the first echo moment and the two echo moments, the transverse relaxation time measurement results at the two echo moments are determined. The ratio of the magnetic resonance signals at the two echo moments is substituted into the functional relationship between the transverse relaxation time and the magnetic resonance signal, respectively, to obtain the first functional relationship and the second functional relationship; according to the ratio of the first functional relationship and the second functional relationship, the ratio of the magnetic resonance signals at the two echo moments is determined. The ratio of the first functional relationship and the second functional relationship is calculated, and the ratio is used as the ratio of the magnetic resonance signals at the two echo moments. For any two echo moments, the method substitutes the magnetic resonance signals at the two echo moments and the corresponding echo moments into the functional relationship respectively, calculates the magnetic resonance signal ratio corresponding to the two functional relationships by dot division, and then substitutes the preset ratio relationship into the magnetic resonance signal ratio, so as to quickly calculate the transverse relaxation time measurement results of the two echo moments, reduce the time required for the calculation process, and improve the calculation efficiency of the transverse relaxation time measurement results of the two echo moments.

[0079] In one embodiment, Figure 6 As shown, the specific contents of determining the transverse relaxation time measurement results at two echo moments according to the ratio relationship between the two echo moments and the ratio of the magnetic resonance signals at the first echo moment and the two echo moments are introduced, and the specific contents include:

[0080] S501, calculating the product of the ratio relationship between the two echo moments and the first echo moment to obtain a product result.

[0081] In the embodiment of the present application, after obtaining the ratio relationship between the two echo moments, the computer device can calculate the product between the ratio relationship between the two echo moments and the first echo moment to obtain a product result. For example, the product result can be expressed as:

[0082]

[0083] S502, obtaining the ratio of the product result to the logarithm of the ratio of the magnetic resonance signals at the two echo times, and taking the negative of the ratio as the transverse relaxation time measurement result at the two echo times.

[0084] In the embodiment of the present application, the transverse relaxation time measurement results at two echo moments can be expressed as:

[0085]

[0086] Wherein, Res(i, j) represents the ratio result of the magnetic resonance images corresponding to the magnetic resonance signals at two echo moments.

[0087] In the above-mentioned method for measuring transverse relaxation time of magnetic resonance, the ratio relationship between two echo moments and the product between the first echo moment are calculated to obtain the product result; the ratio of the product result and the logarithm of the ratio of the magnetic resonance signals at the two echo moments is obtained; and the negative of the ratio is used as the transverse relaxation time measurement result of the two echo moments. The method calculates the ratio relationship between the two echo moments and the product between the first echo moment by multiplication, then calculates the ratio of the product result and the logarithm of the ratio of the magnetic resonance signals, and calculates the negative of the ratio, so as to accurately calculate the transverse relaxation time measurement result of the two echo moments.

[0088] The above embodiments are all descriptions of the specific process of determining the transverse relaxation time measurement results of any two echo moments. Then, the following is a description of the method of determining the magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results of any two echo moments through an embodiment. Figure 7 As shown, the specific method includes:

[0089] S601: When the at least two echo times include two echo times, use the transverse relaxation time measurement results of the two echo times as the magnetic resonance transverse relaxation time measurement results.

[0090] In an embodiment of the present application, when at least two echo moments are two echo moments, the corresponding transverse relaxation time measurement result is one. Then, after the computer device obtains the transverse relaxation time measurement results of the two echo moments, it can directly use the transverse relaxation time measurement result as the magnetic resonance transverse relaxation time measurement result.

[0091] S602: When the at least two echo moments include three or more echo moments, an average value of the transverse relaxation time measurement results of the at least two echo moments is used as the magnetic resonance transverse relaxation time measurement result.

[0092] In an embodiment of the present application, when at least two echo moments are three echo moments, the corresponding transverse relaxation time measurement results are two. When at least two echo moments are more than three echo moments, the corresponding transverse relaxation time measurement results are more than two. In both cases, the computer device can calculate the average value of the transverse relaxation time measurement results of at least two echo moments, and use the average value as the magnetic resonance transverse relaxation time measurement result.

[0093] In the above-mentioned magnetic resonance transverse relaxation time determination method, when at least two echo moments include two echo moments, the transverse relaxation time determination results of the two echo moments are used as the magnetic resonance transverse relaxation time determination result; when at least two echo moments include three or more echo moments, the average value of the transverse relaxation time determination results of the at least two echo moments is used as the magnetic resonance transverse relaxation time determination result. The method flexibly calculates the magnetic resonance transverse relaxation time determination result by different calculation methods under different numbers of echo moments by different situations, so that the magnetic resonance transverse relaxation time determination result is more accurate.

[0094] As a specific embodiment of the present application, the magnetic resonance transverse relaxation time determination process is described in detail below. In one embodiment, Figure 8 As shown, the magnetic resonance transverse relaxation time determination method comprises:

[0095] S701, acquiring magnetic resonance signals at at least two echo moments; the magnetic resonance signals are acquired by applying a spin echo sequence to a region of interest of an acquisition object according to a preset ratio relationship; the ratio relationship represents a time ratio of at least two echo moments; any two echo moments include a first echo moment and a second echo moment;

[0096] S702, respectively substituting the ratio of the magnetic resonance signals at the two echo times into the functional relationship between the transverse relaxation time and the magnetic resonance signal to obtain a first functional relationship and a second functional relationship;

[0097] S703, calculating the ratio of the first functional relationship to the second functional relationship, and using the ratio as the ratio of magnetic resonance signals at two echo times;

[0098] S704, calculating the product of the ratio relationship between the two echo moments and the first echo moment to obtain a product result;

[0099] S705, obtaining a ratio of the product result to the logarithm of the ratio of the magnetic resonance signals at two echo times;

[0100] S706, and taking the negative number of the ratio as the transverse relaxation time measurement result at the two echo moments;

[0101] S707, when the at least two echo moments include two echo moments, using the transverse relaxation time measurement results of the two echo moments as the magnetic resonance transverse relaxation time measurement results;

[0102] S708: When the at least two echo moments include three or more echo moments, an average value of the transverse relaxation time measurement results of the at least two echo moments is used as the magnetic resonance transverse relaxation time measurement result.

[0103] It should be understood that, although the steps in the flowcharts involved in the above embodiments are displayed in sequence according to the indication of the arrows, these steps are not necessarily executed in sequence according to the order indicated by the arrows. Unless there is a clear explanation in this article, the execution of these steps is not strictly limited in order, and these steps can be executed in other orders. Moreover, at least a part of the steps in the flowcharts involved in the above embodiments may include multiple steps or multiple stages, and these steps or stages are not necessarily executed at the same time, but can be executed at different times, and the execution order of these steps or stages is not necessarily carried out in sequence, but can be executed in turn or alternately with other steps or at least a part of the steps or stages in other steps.

[0104] In an exemplary embodiment, a magnetic resonance transverse relaxation time determination system is also provided, the magnetic resonance transverse relaxation time determination system comprising a magnetic resonance device and a computer device;

[0105] A magnetic resonance device, used for acquiring magnetic resonance signals at at least two echo moments according to a preset ratio relationship when a spin echo sequence is applied to a region of interest of an acquisition object; the ratio relationship represents a time ratio of at least two echo moments; any two echo moments include a first echo moment and a second echo moment;

[0106] The computer device is used to determine the transverse relaxation time measurement results of any two echo moments according to the ratio relationship between at least two echo moments, the first echo moment and the magnetic resonance signal; based on the transverse relaxation time measurement results of any two echo moments, determine the magnetic resonance transverse relaxation time measurement result.

[0107] The magnetic resonance transverse relaxation time determination system comprises a magnetic resonance device and a computer device; the magnetic resonance device is used to collect magnetic resonance signals at at least two echo moments according to a preset ratio relationship when a spin echo sequence is applied to a region of interest of an acquisition object; the ratio relationship represents a time ratio of at least two echo moments; any two echo moments include a first echo moment and a second echo moment;

[0108] The computer device is used to determine the transverse relaxation time measurement results of any two echo moments according to the ratio relationship of at least two echo moments, the first echo moment and the magnetic resonance signal; and determine the magnetic resonance transverse relaxation time measurement results based on the transverse relaxation time measurement results of any two echo moments. The system calculates the transverse relaxation time by numerical calculation method when collecting at least two groups of magnetic resonance signals, greatly shortens the acquisition and calculation time in the process of magnetic resonance transverse relaxation time measurement from the perspectives of signal acquisition and calculation process, and improves the efficiency of transverse relaxation time measurement.

[0109] Based on the same inventive concept, the embodiment of the present application also provides a magnetic resonance transverse relaxation time measuring device for implementing the magnetic resonance transverse relaxation time measuring method involved above. The implementation scheme for solving the problem provided by the device is similar to the implementation scheme recorded in the above method, so the specific limitations of one or more magnetic resonance transverse relaxation time measuring device embodiments provided below can refer to the limitations of the magnetic resonance transverse relaxation time measuring method above, and will not be repeated here.

[0110] In an exemplary embodiment, Fig. 9 As shown, a magnetic resonance transverse relaxation time measuring device is provided, comprising: an acquisition module 11, a first determination module 12 and a second determination module 13, wherein:

[0111] The acquisition module 11 is used to acquire magnetic resonance signals at at least two echo moments; the magnetic resonance signals are acquired by applying a spin echo sequence to a region of interest of an acquisition object according to a preset ratio relationship; the ratio relationship represents a time ratio of at least two echo moments; any two echo moments include a first echo moment and a second echo moment;

[0112] A first determination module 12 is used to determine the transverse relaxation time measurement results of any two echo moments according to the ratio relationship between at least two echo moments, the first echo moment and the magnetic resonance signal;

[0113] The second determination module 13 is used to determine the magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results at any two echo moments.

[0114] In an exemplary embodiment, the first determination module includes: an acquisition unit and a first determination unit, wherein:

[0115] An acquisition unit, for acquiring, for any two echo moments, a ratio of the magnetic resonance signals at the two echo moments according to a functional relationship between the magnetic resonance signals at the two echo moments and the transverse relaxation time and the magnetic resonance signals;

[0116] The first determination unit is used to determine the transverse relaxation time measurement results of the two echo moments according to the ratio relationship between the two echo moments and the ratio of the magnetic resonance signals at the first echo moment and the two echo moments.

[0117] In an exemplary embodiment, the acquisition unit is also used to substitute the ratio of the magnetic resonance signals at the two echo moments into the functional relationship between the transverse relaxation time and the magnetic resonance signal, respectively, to obtain a first functional relationship and a second functional relationship; and determine the ratio of the magnetic resonance signals at the two echo moments according to the ratio of the first functional relationship and the second functional relationship.

[0118] In an exemplary embodiment, the above-mentioned first determination unit is also used to calculate the ratio relationship between two echo moments and the product between the first echo moments to obtain a product result; obtain the ratio of the product result and the logarithm of the ratio of the magnetic resonance signals at the two echo moments, and use the negative of the ratio as the transverse relaxation time measurement result of the two echo moments.

[0119] In an exemplary embodiment, the second determination module includes: a second determination unit and a third determination unit, wherein:

[0120] A second determination unit is used for, when the at least two echo moments include two echo moments, using the transverse relaxation time determination results of the two echo moments as the magnetic resonance transverse relaxation time determination results;

[0121] The third determination unit is used to use the average value of the transverse relaxation time measurement results of the at least two echo moments as the magnetic resonance transverse relaxation time measurement result when the at least two echo moments include three or more echo moments.

[0122] Each module in the above-mentioned magnetic resonance transverse relaxation time measuring device can be implemented in whole or in part by software, hardware and a combination thereof. Each of the above-mentioned modules can be embedded in or independent of a processor in a computer device in the form of hardware, or can be stored in a memory in a computer device in the form of software, so that the processor can call and execute the operations corresponding to each of the above modules.

[0123] In an exemplary embodiment, a computer device is provided. The computer device may be a server, and its internal structure diagram may be as shown in FIG. Fig.10 As shown. The computer device includes a processor, a memory, an input / output interface (Input / Output, referred to as I / O) and a communication interface. Among them, the processor, the memory and the input / output interface are connected through a system bus, and the communication interface is connected to the system bus through the input / output interface. Among them, the processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system, a computer program and a database. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The database of the computer device is used to store magnetic resonance transverse relaxation time measurement data. The input / output interface of the computer device is used to exchange information between the processor and an external device. The communication interface of the computer device is used to communicate with an external terminal through a network connection. When the computer program is executed by the processor, a method for measuring magnetic resonance transverse relaxation time is implemented.

[0124] Those skilled in the art will understand that Fig.10The structure shown in the figure is only a block diagram of a part of the structure related to the solution of the present application, and does not constitute a limitation on the computer device to which the solution of the present application is applied. The specific computer device may include more or fewer components than those shown in the figure, or combine certain components, or have a different arrangement of components.

[0125] In an exemplary embodiment, a computer device is provided, including a memory and a processor, wherein a computer program is stored in the memory, and when the processor executes the computer program, the content of any one embodiment of the above-mentioned magnetic resonance transverse relaxation time determination method is implemented.

[0126] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the content of any one embodiment of the magnetic resonance transverse relaxation time determination method is implemented.

[0127] In one embodiment, a computer program product is provided, comprising a computer program, which implements the content of any one of the embodiments of the magnetic resonance transverse relaxation time determination method when executed by a processor.

[0128] It should be noted that the user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data used for analysis, stored data, displayed data, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties, and the collection, use and processing of relevant data must comply with relevant regulations.

[0129] Those skilled in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to the memory, database or other medium used in the embodiments provided in the present application can include at least one of non-volatile memory and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetic random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. As an illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM). The database involved in each embodiment provided in this application may include at least one of a relational database and a non-relational database. Non-relational databases may include distributed databases based on blockchains, etc., but are not limited to this. The processor involved in each embodiment provided in this application may be a general-purpose processor, a central processing unit, a graphics processor, a digital signal processor, a programmable logic device, a data processing logic device based on quantum computing, an artificial intelligence (AI) processor, etc., but are not limited to this.

[0130] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this application.

[0131] The above embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.

Claims

1. A method for measuring magnetic resonance transverse relaxation time, characterized in that: The method comprises: Acquire magnetic resonance signals at at least two echo moments; the magnetic resonance signals are acquired by applying a spin echo sequence to a region of interest of an acquisition object according to a preset ratio relationship; the ratio relationship represents a time ratio of the at least two echo moments; any two echo moments include a first echo moment and a second echo moment; Determine the transverse relaxation time measurement results of the arbitrary two echo moments according to the ratio relationship between the at least two echo moments, the first echo moment and the magnetic resonance signal; Based on the transverse relaxation time measurement results at the arbitrary two echo time points, a magnetic resonance transverse relaxation time measurement result is determined.

2. The method according to claim 1, characterized in that Determining the transverse relaxation time measurement results of the arbitrary two echo moments according to the ratio relationship between the at least two echo moments, the first echo moment and the magnetic resonance signal comprises: For any two echo moments, according to the magnetic resonance signal at the two echo moments, a functional relationship between the transverse relaxation time and the magnetic resonance signal, obtaining a ratio of the magnetic resonance signals at the two echo moments; The transverse relaxation time measurement results of the two echo moments are determined according to the ratio relationship between the two echo moments and the ratio of the magnetic resonance signals at the first echo moment and the two echo moments.

3. The method according to claim 2, characterized in that The step of obtaining the ratio of the magnetic resonance signals at the two echo moments according to the magnetic resonance signals at the two echo moments and the functional relationship between the transverse relaxation time and the magnetic resonance signals comprises: Substituting the ratio of the magnetic resonance signals at the two echo moments into the functional relationship between the transverse relaxation time and the magnetic resonance signal to obtain a first functional relationship and a second functional relationship; The ratio of the magnetic resonance signals at the two echo moments is determined according to the ratio of the first functional relationship to the second functional relationship.

4. The method according to claim 2, characterized in that: Determining the transverse relaxation time measurement results at the two echo moments according to the ratio relationship between the two echo moments and the ratio of the magnetic resonance signals at the first echo moment and the two echo moments comprises: Calculating the product of the ratio relationship between the two echo moments and the first echo moment to obtain a product result; The ratio of the multiplication result to the logarithm of the ratio of the magnetic resonance signals at the two echo moments is obtained, and the negative number of the ratio is used as the transverse relaxation time measurement result at the two echo moments.

5. The method according to any one of claims 1 to 4, characterized in that: The method of determining the magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results at the arbitrary two echo moments comprises: In a case where the at least two echo moments include two echo moments, using the transverse relaxation time measurement results of the two echo moments as the magnetic resonance transverse relaxation time measurement result; When the at least two echo moments include three or more echo moments, an average value of the transverse relaxation time measurement results of the at least two echo moments is used as the magnetic resonance transverse relaxation time measurement result.

6. A magnetic resonance transverse relaxation time measurement system, characterized in that: The magnetic resonance transverse relaxation time determination system comprises a magnetic resonance device and a computer device; The magnetic resonance device is used to collect magnetic resonance signals at at least two echo moments according to a preset ratio relationship when a spin echo sequence is applied to a region of interest of an acquisition object; the ratio relationship represents a time ratio of the at least two echo moments; Any two echo moments include the first echo moment and the second echo moment; The computer device is used to determine the transverse relaxation time measurement results of the arbitrary two echo moments according to the ratio relationship between the at least two echo moments, the first echo moment and the magnetic resonance signal; and determine the magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results of the arbitrary two echo moments.

7. A magnetic resonance transverse relaxation time measuring device, characterized in that: The device comprises: An acquisition module, used for acquiring magnetic resonance signals at at least two echo moments; the magnetic resonance signals are acquired by applying a spin echo sequence to a region of interest of an acquisition object according to a preset ratio relationship; the ratio relationship represents a time ratio of the at least two echo moments; any two echo moments include a first echo moment and a second echo moment; A first determination module, configured to determine the transverse relaxation time measurement results of the arbitrary two echo moments according to the ratio relationship between the at least two echo moments, the first echo moment and the magnetic resonance signal; The second determination module is used to determine the magnetic resonance transverse relaxation time measurement result based on the transverse relaxation time measurement results at the arbitrary two echo moments.

8. A computer device comprising a memory and a processor, wherein the memory stores a computer program, wherein: When the processor executes the computer program, the steps of the method according to any one of claims 1 to 5 are implemented.

9. A computer-readable storage medium having a computer program stored thereon, characterized in that: When the computer program is executed by a processor, the steps of the method according to any one of claims 1 to 5 are implemented.

10. A computer program product, comprising a computer program, characterized in that When the computer program is executed by a processor, the steps of the method according to any one of claims 1 to 5 are implemented.

Images