Oral liquid and preparation method thereof

Abstract

The present invention relates to the technical field of beverages, and in particular to an oral liquid and a preparation method thereof, comprising: a first component and a second component; the first component comprises the following raw materials: collagen peptides, collagen peptides containing collagen tripeptides, skate collagen and tremella polysaccharide; the raw materials of the second component at least include sodium hyaluronate. The oral liquid of the present invention utilizes multiple collagen peptides, elastin peptides, hyaluronic acid and other components to promote each other, and acts on the skin through mechanisms such as hydration, anti-aging, firming, and repair and regeneration, so as to better exert its beauty effect.

Description

Technical Field

[0001] The present invention relates to the technical field of beverages, and in particular to an oral liquid and a preparation method thereof. Background Art

[0002] Collagen is a biopolymer that is mainly distributed in bones, eyes, teeth, tendons, internal organs and skin. 70% of the skin is made up of collagen, which is the most abundant protein in the human body. Collagen has a reticular structure that supports the skin like a spring and affects the elasticity of the skin.

[0003] Hyaluronic acid, also known as hyaluronic acid, is a substance naturally present in tissues and plays the role of a matrix in the human body. It is a high-grade polysaccharide composed of units of D-glucuronic acid and N-acetylglucosamine. Hyaluronic acid has a linear structure and can replace the moisture of the skin. Sodium hyaluronate (SH) is the sodium salt form of hyaluronic acid, which is more stable in nature and is a common form of commercial hyaluronic acid. The end product of enzymatic hydrolysis of SH with different polymerization degrees is hyaluronan disaccharide, which is the smallest structural unit of SH. SH has the functions of improving skin moisture, moisturizing, anti-oxidation, improving skin elasticity and promoting wound healing. The hyaluronic acid molecular chains are intertwined to form a continuous mesh structure. Water molecules directly interact with hyaluronic acid through polar bonds and hydrogen bonds, so that hyaluronic acid can absorb and retain thousands of times its own weight of water. It is internationally recognized as the best moisturizer and is known as the "natural moisturizing factor".

[0004] But as we age, collagen and hyaluronic acid in the skin are gradually lost, causing the skin to lose elasticity and form wrinkles.

[0005] In view of this, the present invention is proposed. Summary of the invention

[0006] The purpose of the present invention is to provide an oral liquid and a preparation method thereof, wherein the oral liquid can systematically increase the content of endogenous hyaluronic acid, thereby increasing the water-retaining capacity of the skin, achieving the effects of moisturizing the skin, reducing wrinkles and delaying aging.

[0007] The first aspect of the present invention provides an oral liquid, comprising: a first component and a second component; the first component comprises the following raw materials: collagen peptides, collagen peptides containing collagen tripeptide, skate collagen and tremella polysaccharide; the raw materials of the second component at least include sodium hyaluronate.

[0008] Preferably, the first component comprises, by weight: 4500-5500 parts of collagen peptides, 0.005-0.015 parts of collagen peptides containing collagen tripeptide, 0.1-2 parts of skate collagen and 0.005-0.015 parts of tremella polysaccharide.

[0009] Preferably, in parts by weight, the first component includes: 5000 parts of collagen peptides, 0.01 parts of collagen peptides containing collagen tripeptide, 1 part of skate collagen and 0.01 parts of tremella polysaccharide.

[0010] Collagen tripeptide is a small molecule collagen that can be directly and quickly absorbed by the skin, increasing the collagen content in the skin, thereby enhancing the skin's elasticity and firmness; it can also stimulate fibroblasts to synthesize collagen, reduce the formation of wrinkles, and make the skin smoother and more delicate; and it is hydrophilic, can absorb and lock in moisture, and keep the skin moisturized.

[0011] The unique composition and golden ratio of ray collagen, collagen peptide + glycosaminoglycan GAGs (chondroitin sulfate, glucosamine, hyaluronic acid, etc.). It is selected from marine cartilaginous fish, rich in collagen and glycosaminoglycan GAGs (100%), and unique proteoglycan components, which can retain matrix moisture, lock in moisture and maintain the skin support structure.

[0012] Tremella polysaccharide can increase the moisture of the surface skin, repair the skin and mucous membranes, promote skin softness and make the skin more elastic.

[0013] Preferably, a second component is also included; the second component includes the following raw materials: bonito elastin peptide, red grape yeast compound powder, yeast extract, niacinamide, xylitol, mangosteen powder, sodium hyaluronate, citric acid, DL-malic acid, acerola cherry powder and stevioside.

[0014] Preferably, the second component comprises, by weight: 0.005-0.015 parts of bonito elastin peptide, 0.1-2 parts of red grape yeast compound powder, 0.1-2 parts of yeast extract, 0.3-0.5 parts of niacinamide, 2500-3500 parts of xylitol, 0.005-0.015 parts of mangosteen powder, 40-60 parts of sodium hyaluronate, 60-70 parts of citric acid, 50-60 parts of DL-malic acid, 40-60 parts of acerola powder and 8-10 parts of stevioside.

[0015] Preferably, the second component comprises, by weight: 0.01 parts of bonito elastin peptide, 1 part of red grape yeast compound powder, 1 part of yeast extract, 0.375 parts of niacinamide, 3000 parts of xylitol, 0.01 parts of mangosteen powder, 50 parts of sodium hyaluronate, 63 parts of citric acid, 52 parts of DL-malic acid, 50 parts of acerola powder and 8.2 parts of stevioside.

[0016] Bonito elastin peptide has the functions and effects of maintaining skin elasticity, replenishing collagen and protecting the skin.

[0017] Glycation of the skin refers to the reaction of free sugars in the skin with proteins to form glycation reaction products (AGEs), which reduce the elasticity of collagen fibers, damage the skin's relaxation ability, and make the skin loose; it also promotes the production of melanin, so anti-aging of the skin also requires anti-glycation. Mangosteen powder is an anti-glycation raw material that has the dual effects of not generating the final glycation product AGEs and decomposing AGEs.

[0018] Niacinamide can affect the movement of substances in melanocytes, effectively inhibiting melanin particles and the transfer of melanin particles to keratinocytes. When some melanin inevitably reaches the surface of the skin, niacinamide can accelerate the renewal of skin cells, thereby promoting the shedding of cells containing melanin, thereby improving skin quality and whitening the skin from the inside out.

[0019] Cherry powder is a natural source of vitamin C and vitamin A, which promotes skin recovery and regeneration and enhances the skin's ability to moisturize and lock in moisture.

[0020] Preferably, a third component is also included; the third component includes the following raw materials: purple carrot concentrated juice, blackcurrant juice, blueberry concentrated juice, concentrated apple juice and blueberry essence.

[0021] Preferably, the third component comprises: 30-50 parts of purple carrot concentrated juice, 0.1-2 parts of blackcurrant juice, 700-900 parts of blueberry concentrated juice, 700-900 parts of concentrated apple juice and 40-60 parts of blueberry essence.

[0022] Preferably, the third component comprises: 39 parts of purple carrot concentrated juice, 1 part of blackcurrant juice, 800 parts of blueberry concentrated juice, 800 parts of concentrated apple juice and 50 parts of blueberry essence.

[0023] Purple carrots can promote the synthesis of collagen, making the skin firmer and more elastic.

[0024] Blackcurrant is rich in many nutrients that are beneficial to the skin, especially vitamin C, which can resist the damage of free radicals to skin cells, reduce the formation of wrinkles, and keep the skin firm and elastic. At the same time, vitamin C can also promote the synthesis of collagen, which is a key substance for maintaining the structure and elasticity of the skin, helping to keep the skin smooth and soft. The content of anthocyanins in blackcurrant is also high. Anthocyanins also have antioxidant effects, which can protect the skin from UV damage, reduce skin inflammation, improve skin dullness, and make the skin glow with a healthy radiance. Blackcurrant also contains a variety of nutrients such as minerals and amino acids, which help regulate skin metabolism and promote the renewal and repair of skin cells.

[0025] Blueberries are rich in anthocyanins, which have the function of scavenging free radicals, thus playing an antioxidant and anti-aging role.

[0026] The vitamins in apples can remove spots, brighten the skin, prevent pigmentation, whiten the skin, moisturize the skin, and make the skin white and translucent.

[0027] In addition, the various fruit and vegetable juices in the third component also have a good effect of adjusting the taste of the oral solution.

[0028] In addition to the above components, the oral solution also includes water.

[0029] The second aspect of the present invention provides a method for preparing an oral liquid, comprising the following steps:

[0030] S1. Mix the first component and add purified water to mix thoroughly;

[0031] S2, adding the second component, soaking, and boiling;

[0032] S3, adding the third component, mixing thoroughly, and boiling to obtain an extract;

[0033] S4. Filter the extract obtained by decoction to obtain an extract stock solution, sterilize the extract stock solution at high temperature, and test the sugar-acid ratio and microbial content. After the test, aseptically package the extract stock solution to obtain the oral liquid.

[0034] Preferably, the method comprises the following steps:

[0035] S1. Mix 4500-5500 parts of collagen peptide, 0.005-0.015 parts of collagen peptide containing collagen tripeptide, 0.1-2 parts of skate collagen, and 0.005-0.015 parts of Tremella polysaccharide, and add purified water to mix them thoroughly;

[0036] S2, add 0.005-0.015 parts of bonito elastin peptide, 0.1-2 parts of red grape yeast compound powder, 0.1-2 parts of yeast extract, 0.3-0.5 parts of niacinamide, 2500-3500 parts of xylitol, 0.005-0.015 parts of mangosteen powder, 40-60 parts of sodium hyaluronate, 60-70 parts of citric acid, 50-60 parts of DL-malic acid, 40-60 parts of acerola powder, 8-10 parts of steviol glycoside, soak for 0.5-1h, and boil at 80-100℃ for 2 times, each time for 30-60min;

[0037] S3, add 30-50 parts of purple carrot juice concentrate, 0.1-2 parts of blackcurrant juice, 700-900 parts of blueberry juice concentrate, 700-900 parts of apple juice concentrate, and 40-60 parts of blueberry essence, mix well, and boil at 80-100° C. for 2 times, each time for 30-60 minutes;

[0038] S4. The extracts obtained from the two decoctions are combined, filtered to obtain the original extract solution, sterilized at high temperature, and tested for the sugar-acid ratio and microbial content. After the test, the original extract solution is aseptically packaged to obtain the oral liquid.

[0039] The oral liquid of the present invention is prepared by using a variety of collagen peptides, elastin peptides and hyaluronic acid as well as other multiple components. The multiple components act synergistically with each other and have at least the following beneficial effects:

[0040] (1) Hyaluronic acid has a strong water-carrying capacity and can firmly retain moisture, provide moisture to the skin and maintain moisture. Collagen also has a good moisturizing effect and can replenish and lock moisture for the skin. When hyaluronic acid absorbs a large amount of water, it puts elastin and collagen in an environment full of moisture, making the skin more elastic. In addition, when collagen and hyaluronic acid work together, they can form a protective film on the skin surface to prevent the external environment from irritating and damaging the skin. This protective film helps to reduce the loss of hyaluronic acid, thereby improving its absorption efficiency.

[0041] (2) Collagen can enhance the elasticity and firmness of the skin and improve the structure of the skin by filling local skin collapse, improving sagging, and tightening the skin. This improvement helps the skin better absorb and retain active ingredients such as hyaluronic acid.

[0042] (3) Exogenous hyaluronic acid donors can promote the repair of damaged tissues in a short period of time, increase blood circulation in capillaries, and improve the skin's stress response and adaptability to changes in the external environment; while collagen, as a cell growth attachment and scaffold, can induce the proliferation, differentiation and migration of epithelial cells, and play a promoting and inducing role during wound healing and tissue remodeling. The two work synergistically to promote cell repair.

[0043] (4) Collagen peptide is a bioactive peptide with multiple biological activities. It inhibits oxidative stress through multiple mechanisms. Collagen peptide can act as an antioxidant to directly remove reactive oxygen species (ROS) and free radicals to prevent them from damaging cells. In addition, collagen peptide can also inhibit oxidative stress by inhibiting inflammatory response and inhibit oxidative stress by regulating the activity of antioxidant enzymes. Hyaluronic acid not only has moisturizing and repairing effects, but also has the effects of promoting proliferation, differentiation and scavenging free radicals. The cooperation between the two is of great significance for protecting the skin from free radicals, reducing the formation of skin wrinkles and spots, and anti-aging.

[0044] (5) Collagen tripeptide, as a small molecule collagen, can be directly and quickly absorbed by the skin, while skate collagen and bonito elastin peptide also have good absorbability. The multiple components work together to make them easier to be absorbed and utilized by the body.

[0045] In summary, the oral liquid of the present invention utilizes multiple collagen peptides, elastin peptides, hyaluronic acid and other components to cooperate with each other to promote each other, and jointly act on the skin through mechanisms such as hydration, moisturizing, anti-aging, firming, and repair and regeneration, thereby better exerting its beauty effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0046] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0047] Figure 1 This is a diagram showing the effects of the oral liquid provided by the present invention on subjects taking the liquid. DETAILED DESCRIPTION

[0048] It should be noted that the following detailed descriptions are illustrative and are intended to provide further explanation of the present application. Unless otherwise specified, all technical and scientific terms used herein have the same meanings as those commonly understood by those skilled in the art to which the present application belongs.

[0049] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form also includes the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.

[0050] The technical solution of the present invention will be clearly and completely described below in conjunction with the embodiments. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0051] Example

[0052] This embodiment provides an oral liquid, comprising: a first component, a second component and a third component;

[0053] The first component includes the following raw materials: 5000g collagen peptide, 0.01g collagen peptide containing collagen tripeptide, 1g ray collagen and 0.01g tremella polysaccharide;

[0054] The second component includes the following raw materials: 0.01g bonito elastin peptide, 1g red grape yeast compound powder, 1g yeast extract, 0.375g niacinamide, 3000g xylitol, 0.01g mangosteen powder, 50g sodium hyaluronate, 63g citric acid, 52g DL-malic acid, 50g acerola powder and 8.2g stevioside;

[0055] The third component includes the following raw materials: 39 g of purple carrot juice concentrate, 1 g of black currant juice (black currant), 800 g of wild blueberry juice concentrate, 800 g of concentrated apple juice and 50 g of blueberry essence.

[0056] This embodiment also provides a method for preparing an oral liquid, characterized in that it comprises the following steps:

[0057] S1. Add 5000 g collagen peptide, 0.01 g collagen peptide containing collagen tripeptide, 1 g skate collagen, and 0.01 g Tremella polysaccharide into a bucket and add 21 kg purified water to mix them thoroughly;

[0058] S2, add 0.01g bonito elastin peptide, 1g red grape yeast compound powder, 1g yeast extract, 0.375g niacinamide, 3000g xylitol, 0.01g mangosteen powder, 50g sodium hyaluronate, 63g citric acid, 52g DL-malic acid, 50g acerola powder, 8.2g stevioside to the barrel, soak for 0.5h, and boil at 90℃ for 2 times, each time for 45min;

[0059] S3, add 39g of purple carrot juice concentrate, 1g of black currant juice (black currant), 800g of wild blueberry juice concentrate, 800g of concentrated apple juice, and 50g of blueberry essence to the barrel, mix well, and boil at 90°C for 2 times, each time for 45min;

[0060] S4. Combine the extracts obtained from the two decoctions, filter for 16 hours to obtain the original extract, sterilize the original extract at 121°C, and test the sugar-acid ratio and microbial content. After the test, aseptically package and store in a 4°C freezer for 24 hours.

[0061] After taking the oral solution of this embodiment, the experimenters tested the following eight indicators: moisture content of the stratum corneum, skin gloss, skin b value, skin melanin value, skin elasticity parameter R2 value, skin elasticity F4 value, skin smoothness parameter sEsm value, and the area ratio of wrinkles at the corners of the eyes (crow's feet) at 2, 4, and 8 weeks of use. The test results are shown in Figure 1 ,from Figure 1It can be seen that the oral liquid can significantly increase the moisture content of the stratum corneum of the skin; the skin glossiness value significantly increases; the skin b value significantly decreases; the skin melanin value significantly decreases; the skin elasticity parameter F4 value significantly decreases; the skin elasticity parameter R2 value significantly increases; the skin smoothness parameter SEsm value significantly decreases; the area ratio of wrinkles at the corners of the eyes (crow's feet) significantly decreases. The statistical method uses a two-tailed test with a test level of a=0.05. At the same time, the changes in the skin smoothness parameter SEsm value of 38 subjects at different time points are statistically analyzed. After using the product for 8 weeks, it is significantly decreased compared with before using the product (p<0.001), and the decrease rate is 23.6%. The lower the measured value SEsm value, the smoother the skin.

[0062] Comparative Example 1

[0063] This comparative example is basically the same as the embodiment, except that: this comparative example does not add the first component.

[0064] Comparative Example 2

[0065] This comparative example is basically consistent with the embodiment, except that: the first component and the second component are not added in this comparative example.

[0066] Test Case

[0067] After taking the oral liquids of Example and Comparative Examples 1-2 for 8 weeks, the subjects were tested for melanin, skin smoothness, skin elasticity and wrinkle area. The results are shown in Table 1.

[0068] Table 1

[0069] project Melanin test Skin smoothness test Skin elasticity test Wrinkle area Example Low Significant decline rise Low Comparative Example 1 Higher constant decline high Comparative Example 2 Very high rise decline high

[0070] It can be seen from Table 1 that compared with the oral liquids of Comparative Examples 1 and 2, after taking the oral liquid of the embodiment, the skin melanin value is lower, the skin smoothness parameter SEsm value is significantly decreased, the skin elasticity parameter value is significantly increased, and the area ratio of wrinkles at the canthus (crow's feet) is significantly decreased.

[0071] In summary, the oral liquid of the present invention utilizes multiple collagen peptides, elastin peptides, hyaluronic acid and other components to cooperate with each other to promote each other, and jointly act on the skin through mechanisms such as hydration, moisturizing, anti-aging, firming, and repair and regeneration, thereby better exerting its beauty effect.

[0072] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. An oral liquid, characterized in that: The invention comprises: a first component and a second component; the first component comprises the following raw materials: collagen peptide, collagen peptide containing collagen tripeptide, skate collagen and tremella polysaccharide; the raw materials of the second component at least comprise sodium hyaluronate.

2. The oral liquid according to claim 1, characterized in that In parts by weight, the first component includes: 4500-5500 parts of collagen peptides, 0.005-0.015 parts of collagen peptides containing collagen tripeptide, 0.1-2 parts of ray collagen and 0.005-0.015 parts of tremella polysaccharide.

3. The oral liquid according to claim 2, characterized in that In terms of weight, the first component includes: 5000 parts of collagen peptides, 0.01 parts of collagen peptides containing collagen tripeptide, 1 part of ray collagen and 0.01 parts of tremella polysaccharide.

4. The oral liquid according to claim 1, characterized in that The invention also comprises a second component; the second component comprises the following raw materials: bonito elastin peptide, red grape yeast compound powder, yeast extract, niacinamide, xylitol, mangosteen powder, sodium hyaluronate, citric acid, DL-malic acid, acerola powder and stevioside.

5. The oral liquid according to claim 4, characterized in that The second component comprises, by weight: 0.005-0.015 parts of bonito elastin peptide, 0.1-2 parts of red grape yeast compound powder, 0.1-2 parts of yeast extract, 0.3-0.5 parts of niacinamide, 2500-3500 parts of xylitol, 0.005-0.015 parts of mangosteen powder, 40-60 parts of sodium hyaluronate, 60-70 parts of citric acid, 50-60 parts of DL-malic acid, 40-60 parts of acerola powder and 8-10 parts of stevioside.

6. The oral liquid according to claim 5, characterized in that The second component includes, by weight: 0.01 parts of bonito elastin peptide, 1 part of red grape yeast compound powder, 1 part of yeast extract, 0.375 parts of niacinamide, 3000 parts of xylitol, 0.01 parts of mangosteen powder, 50 parts of sodium hyaluronate, 63 parts of citric acid, 52 parts of DL-malic acid, 50 parts of acerola powder and 8.2 parts of stevioside.

7. The oral liquid according to claim 1, characterized in that The invention also comprises a third component, which comprises the following raw materials: concentrated purple carrot juice, blackcurrant juice, concentrated blueberry juice, concentrated apple juice and blueberry essence.

8. The oral liquid according to claim 7, characterized in that The third component comprises, by weight: 30-50 parts of purple carrot concentrated juice, 0.1-2 parts of blackcurrant juice, 700-900 parts of blueberry concentrated juice, 700-900 parts of concentrated apple juice and 40-60 parts of blueberry essence.

9. The oral liquid according to claim 8, characterized in that The third component comprises, by weight, 39 parts of purple carrot concentrated juice, 1 part of blackcurrant juice, 800 parts of blueberry concentrated juice, 800 parts of concentrated apple juice and 50 parts of blueberry essence.

10. A method for preparing an oral liquid, characterized in that: The steps include: S1. Mix the first component and add purified water to mix thoroughly; S2, adding the second component, soaking, and boiling; S3, adding the third component, mixing thoroughly, and boiling to obtain an extract; S4. Filter the extract obtained by decoction to obtain an extract stock solution, sterilize the extract stock solution at high temperature, and test the sugar-acid ratio and microbial content. After the test, aseptically package the extract stock solution to obtain the oral liquid.

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