A molecular biology experimental sample grinder

By switching the design of the grinding assembly and quantitative cooling assembly, the inconvenience of operating the sample grinder in molecular biology under different sample sizes and types is solved, and efficient and convenient sample grinding is achieved, adapting to various experimental occasions.

CN119747041BActive Publication Date: 2025-08-15黑河海关综合技术中心
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Patent Information

Application Number
CN202411998039.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-12-31
Publication Date
2025-08-15
Estimated Expiration
2044-12-31

AI Technical Summary

Technical Problem

The existing molecular biology experimental sample grinder is inconvenient to operate under different sample sizes and types, is large in size and is not easy to carry, and has low grinding efficiency, so the grinding device needs to be replaced several times.

Method used

Switching grinding components and quantitative cooling components are designed, combined with grinding auxiliary components to realize quantitative distribution of samples and semi-automatic continuous grinding, adapt to different experimental needs and reduce liquid nitrogen consumption.

Benefits of technology

It improves the experimental efficiency, adapts to the grinding needs of different samples and types, is easy to carry, is easy to operate, has a wide range of applications, and is efficient in grinding effect.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a molecular biology experimental sample grinder, which relates to the technical field of grinders. A switching grinding assembly is provided on the outer side of a mortar, the top end of the mortar rod is movably connected to the output shaft end of the grinding motor, the other end of the bottom surface of the horizontal connecting rod is connected to a pulling rod, the bottom end of the guide tube is fixedly connected to the bottom surface of a support seat, and feeding guide rails are installed at both ends of the feeding hole, one end of the feeding plate passes through the lifting hole and is connected to a screw rod through a screw hole, a suction cup is installed through one side of the fixed semi-ring, a grinding auxiliary assembly is installed inside the mortar, and a quantitative cooling assembly is sleeved on the outer side of the mortar. The invention can adopt different structures and processing methods according to needs, when the amount to be ground is small, whether liquid nitrogen cooling is required, and the amount of experimental samples is large or the types are large. When the amount is small, fewer structures are used and it is easy to carry and move. When the amount is large, semi-automatic continuous grinding is performed, the operation is convenient, the grinding efficiency is high, and it is suitable for a variety of different experiments and experimental occasions, and has a wider range of applications.
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Description

Technical Field

[0001] The invention relates to the technical field of grinders, in particular to a molecular biology experimental sample grinder. Background Art

[0002] Molecular biology experiments are a discipline practice that studies life phenomena and their material basis at the molecular level. They aim to reveal the structure, function, and interaction mechanism of biological macromolecules (such as DNA, RNA, and proteins). When conducting experiments, it is often necessary to extract DNA or RNA from experimental samples. During the extraction process, the experimental samples need to be ground to break up the cells to facilitate subsequent extraction.

[0003] The patent application number 202321481493.6 mentions "a molecular biology experimental sample grinder". This technical solution can adapt to the grinding of samples of different specifications or quantities, control the uniformity and sufficiency of grinding, reduce sample residue, and thus improve the efficiency of the experiment. However, in actual operation, different samples require different grinding methods, and the amount of samples required for different experiments is also different. The sample amount is small, and the above-mentioned device is large in size, not easy to carry, and inconvenient to operate. When continuously grinding different samples, it is necessary to change the grinder multiple times, which is time-consuming and has low grinding efficiency. Summary of the Invention

[0004] The present invention provides a molecular biology experimental sample grinder, which can effectively solve the problems raised in the above background technology that different samples require different grinding methods in actual operation, and the sample amount required for different experiments is also different. The sample amount is small, the above device is large in size, not easy to carry, and inconvenient to operate. When continuously grinding different samples, it is necessary to change the grinder multiple times, the operation is time-consuming, and the grinding efficiency is low.

[0005] To achieve the above object, the present invention provides the following technical solution: a molecular biology experimental sample grinder, comprising a mortar, a switchable grinding assembly is provided on the outer side of the mortar, and the switchable grinding assembly includes a mortar rod;

[0006] The top of the feeding screw is connected to the output shaft of the feeding motor, and the top of the feeding motor is connected to one end of the bottom surface of the horizontal connecting rod, and the other end of the bottom surface of the horizontal connecting rod is connected to a pulling rod, and the bottom end of the pulling rod is movably sleeved on a guide tube, and the bottom end of the guide tube is fixedly connected to the bottom surface of the support seat, and the support seat is provided with a feeding hole at the bottom end of the mortar, and the two ends of the feeding hole are equipped with a feeding guide rail. The bottom of the feeding hole is provided with an embedding groove, and the middle part of the inner side of the feeding hole is provided with a lifting hole. A feeding plate is movably embedded in the embedding groove, and one end of the feeding plate passes through the lifting hole and is connected to a feeding screw rod through a screw hole. The top of the feeding screw rod is connected to the output shaft of the feeding motor, and the feeding motor is installed on one side of the fixed semi-ring, and the fixed semi-ring is fixedly installed on one side of the top of the feeding hole, and a suction cup is installed on one side of the fixed semi-ring;

[0007] A grinding auxiliary component is installed inside the mortar, a quantitative cooling component is sleeved on the outside of the mortar, and an insulating sleeve is sleeved on the outside of the quantitative cooling component. A movable half ring is fixedly installed on one side of the insulating sleeve, and a switching tube is fixedly installed on the middle part of one side of the movable half ring. A switching rod is movably installed inside the switching tube, and the top of the switching rod is fixedly connected to one end of the steering plate, and a clamping tube is movably installed on the other end of the steering plate, and a rotating handle is welded on the top of the clamping tube.

[0008] According to the above technical solution, the grinding auxiliary component includes a grinding head;

[0009] The bottom end of the bowl rod is fixedly connected to a grinding head, the top of the grinding head is symmetrically fixedly installed with an upper baffle, the middle of the grinding head is symmetrically fixedly installed with a lower baffle, grinding balls are placed inside the mortar, the middle of the bowl rod is sleeved with a support spring, the top of the bowl rod is movably sleeved with an end cover, the edge of the end cover is welded with a rib, and the top surface of the rib is evenly provided with filling holes.

[0010] According to the above technical solution, the quantitative cooling assembly includes an annular cooling box;

[0011] An annular cooling box is sleeved on the outside of the mortar, and a retaining ring is fixedly installed inside the annular cooling box. Extrusion holes are symmetrically provided on the bottom end of the retaining ring, and an extrusion ring is movably sleeved on the top end of the retaining ring. A cooling screw is installed on one side of the extrusion ring through a screw hole. The top end of the annular cooling box is in contact with a top cover box, and the top end of the cooling screw rotates through the top cover box and is connected to a knob. Injection holes are provided on the bottom surface of the top cover box aligned with the retaining edge, and a blocking ring is rotatably inlaid on the inner edge of the top end of the top cover box. A right-angle block is fixedly installed at the bottom end of the blocking ring corresponding to the injection hole. A limited block is provided near the injection hole of the top cover box, and a toggle rod is fixedly installed on one side of the top surface of the blocking ring.

[0012] According to the above technical solution, the inner bottom end of the mortar is rounded, the cross section of the rib is a right angle, and the rib and the top end of the mortar are connected in a transition fit manner.

[0013] According to the above technical solution, the distance between the upper baffle and the lower baffle is smaller than the diameter of the grinding ball, the ends and edges of the upper baffle and the lower baffle are rounded, and the spatial angle between the upper baffle and the lower baffle is 90°.

[0014] According to the above technical solution, a motor tray is installed on one side of the fixed half ring, the feeding motor is installed on the top surface of the motor tray, and the output shaft of the feeding motor movably passes through the motor tray.

[0015] According to the above technical solution, the cross-section of the top cover box is a hollow right angle with an open bottom end, the top of the retaining ring contacts the inner top surface of the top cover box, the outer side of the shielding ring fits into the inner wall of the annular cooling box close to the outside, and the inner side of the shielding ring fits into the outer side of the retaining ring.

[0016] According to the above technical solution, a limiting groove is opened at the bottom of the mortar, and an iron strip is embedded at the top of the limiting groove. The limiting guide rails are fixedly installed in the middle of the top surface of the feeding guide rail and the feeding plate, and a magnetic strip is bonded to the top surface of the limiting guide rail.

[0017] According to the above technical solution, the input ends of the grinding motor and the feeding motor are electrically connected to the output end of the external power supply respectively, the diameter of the mortar is equal to the diameter of the embedding groove, and the top edge of the embedding groove is chamfered.

[0018] According to the above technical solution, the pulling rod is a hexagonal prism, the conduit is a circular tube with a regular hexagonal hole in the middle, and the fixed half ring and the movable half ring are spliced into a circular ring shape.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] 1. A switching grinding assembly is provided. When the amount to be ground is large or there are many types, the samples are quantitatively distributed and placed in each mortar in turn. The mortars are placed in the feed guide rail on one side in turn, and the insulation sleeve is placed close to the fixed half ring. The suction cup adsorbs the insulation sleeve on one side and fixes the insulation sleeve. The mortar enters the embedding groove, and the feed plate drives the mortar to be embedded in the annular cooling box. The top end of the mortar rod and the bottom end of the grinding motor are snap-connected. After grinding is completed, the mortar rod returns to the embedding groove, and grinding is carried out continuously in a semi-automatic manner, which is convenient for sample processing when the amount or types are large, and effectively improves the experimental efficiency.

[0021] 2. A grinding auxiliary component is provided. When the amount to be ground is small and cooling is not required, take the mortar and place it on a horizontal operating table, place the experimental sample in the mortar, put in the grinding head and grinding balls, connect the end cover to the top of the mortar rod, take the card tube, and movably connect the card tube to the top of the mortar rod. Hold the rotating handle and turn it. The grinding head grinds the experimental sample at the bottom end of the mortar. During the grinding process, the upper baffle and the lower baffle will alternately hit the grinding balls, and the grinding balls hit the inside of the mortar, vibrating the inside of the mortar. The experimental material adhered to the inner wall of the mortar slides to the bottom end of the mortar under the multiple effects of impact, vibration and gravity. Continue grinding to ensure sufficient grinding.

[0022] 3. A quantitative cooling component is provided. When cooling is required, an insulating sleeve is connected to the outside of the annular cooling box, and liquid nitrogen is poured into the annular cooling box. The rotating cooling screw drives the extrusion ring to move downward, and the squeezed liquid nitrogen flows from the extrusion hole at the bottom of the retaining ring, and then discharged from the injection hole to the top surface of the retaining edge, and flows into the mortar through the filling hole. With the switching rod in the switching tube as the axis, the steering plate is rotated, the clamping tube is aligned with the top of the mortar rod, and the handle is turned to grind. After one grinding is completed, the mortar is pushed out of the annular cooling box, and a new mortar with the experimental sample already placed is put in for re-grinding. Quantitative control is convenient for adding liquid nitrogen and saving liquid nitrogen, thereby improving the convenience of operation.

[0023] In summary, different structures and processing methods can be used according to needs, such as when the amount to be ground is small, whether liquid nitrogen cooling is required, and when the amount of experimental samples is large or there are many types. When the amount is small, fewer structures are used and it is easy to carry and move. When the amount is large, semi-automatic continuous grinding is convenient to operate and has high grinding efficiency. It is suitable for a variety of different experiments and experimental occasions and has a wider range of applications.

[0024] The grinding auxiliary component relies on the collision of grinding balls to improve the grinding effect while reducing adhesion. The quantitative cooling component facilitates the quantitative addition of liquid nitrogen while reducing liquid nitrogen consumption and saving materials. It can be combined with the switching grinding component according to different experimental needs to achieve better and more efficient grinding results. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention.

[0026] In the attached figure:

[0027] Figure 1 It is a structural schematic diagram of the present invention;

[0028] Figure 2 It is a structural schematic diagram of the switching grinding assembly of the present invention;

[0029] Figure 3Schematic diagram of the installation structure of the suction cup of the present invention;

[0030] Figure 4 This is a schematic diagram of the installation structure of the iron strip of the present invention;

[0031] Figure 5 It is a schematic diagram of the installation structure of the feed plate of the present invention;

[0032] Figure 6 is a schematic structural diagram of the grinding auxiliary assembly of the present invention;

[0033] Figure 7 It is a schematic structural diagram of the quantitative cooling assembly of the present invention;

[0034] Figure 8 This is a schematic diagram of the installation structure of the right-angle stop of the present invention;

[0035] Numbers in the figure: 1, mortar;

[0036] 2. Switching grinding assembly; 201. Bowl rod; 202. Grinding motor; 203. Horizontal connecting rod; 204. Pulling rod; 205. Guide tube; 206. Support seat; 207. Feeding hole; 208. Feeding guide rail; 209. Embedding slot; 210. Lifting hole; 211. Feed plate; 212. Feed screw; 213. Feeding motor; 214. Fixed half ring; 215. Suction cup; 216. Insulation sleeve; 217. Movable half ring; 218. Switching tube; 219. Switching rod; 220. Steering plate; 221. Adapter tube; 222. Turning handle;

[0037] 21. Grinding auxiliary assembly; 2101. Grinding head; 2102. Upper baffle; 2103. Lower baffle; 2104. Grinding balls; 2105. Support spring; 2106. End cap; 2107. Side rib; 2108. Filling port;

[0038] 22. Quantitative cooling assembly; 2201. Annular cooling box; 2202. Retaining ring; 2203. Extrusion hole; 2204. Extrusion ring; 2205. Cooling screw; 2206. Top cover box; 2207. Knob; 2208. Injection hole; 2209. Shielding ring; 2210. Right-angle stop; 2211. Limit stop; 2212. Toggle lever;

[0039] 3. Motor tray; 4. Limiting slot; 5. Iron strip; 6. Limiting guide rail; 7. Magnetic strip. DETAILED DESCRIPTION

[0040] The preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0041] Example: Figure 1-8As shown, the present invention provides a technical solution for a molecular biology experimental sample grinder, comprising a mortar 1, a switch grinding assembly 2 is provided on the outer side of the mortar 1, and the switch grinding assembly 2 comprises a mortar rod 201, a grinding motor 202, a horizontal connecting rod 203, a pulling rod 204, a guide tube 205, a support seat 206, a loading hole 207, a feeding guide rail 208, an embedding groove 209, a lifting hole 210, a feeding plate 211, a feeding screw 212, a feeding motor 213, a fixed half ring 214, a suction cup 215, a grinding auxiliary assembly 21, a quantitative cooling assembly 22, a heat insulating sleeve 216, a movable half ring 217, a switching tube 218, a switching rod 219, a steering plate 220, a clamping tube 221 and a rotating handle 222;

[0042] A mortar rod 201 is placed inside the mortar 1. The top of the mortar rod 201 is movably connected to the output shaft end of the grinding motor 202. The top of the grinding motor 202 is connected to one end of the bottom surface of the horizontal connecting rod 203. The other end of the bottom surface of the horizontal connecting rod 203 is connected to a pulling rod 204. The bottom end of the pulling rod 204 is movably sleeved with a guide tube 205. The bottom end of the guide tube 205 is fixedly connected to the bottom surface of the support seat 206. The support seat 206 is located at the bottom end of the mortar 1 and is provided with a feeding hole 207. Both ends of the feeding hole 207 are equipped with feeding guide rails 208. The input ends of the grinding motor 202 and the feeding motor 213 are electrically connected to the output end of the external power supply respectively. The diameter of the mortar 1 is equal to the diameter of the embedding groove 209. The top edge of the embedding groove 209 is chamfered to facilitate the mortar 1 to enter the embedding groove 209. The bottom end of the loading hole 207 is provided with an embedding groove 209, and the middle part of the inner side of the loading hole 207 is provided with a lifting hole 210. A feeding plate 211 is movably embedded in the groove 209, a limiting groove 4 is provided at the bottom end of the mortar 1, an iron strip 5 is inlaid on the top of the limiting groove 4, a limiting guide rail 6 is fixedly installed in the middle of the top surface of the feeding guide rail 208 and the feeding plate 211, and a magnetic strip 7 is bonded to the top surface of the limiting guide rail 6, which is convenient for smoothly pushing the mortar 1 to move, one end of the feeding plate 211 passes through the lifting hole 210 and is connected to the feeding screw 212 through a screw hole, the top of the feeding screw 212 is connected to the output shaft of the feeding motor 213, a motor tray 3 is installed on one side of the fixed semi-ring 214, the feeding motor 213 is installed on the top surface of the motor tray 3, and the output shaft of the feeding motor 213 movably passes through the motor tray 3, which is convenient for installing the feeding motor 213, the feeding motor 213 is installed on one side of the fixed semi-ring 214, the fixed semi-ring 214 is fixedly installed on one side of the top of the loading hole 207, and a suction cup 215 is installed on one side of the fixed semi-ring 214;

[0043] A grinding auxiliary component 21 is installed inside the mortar 1, a quantitative cooling component 22 is sleeved on the outside of the mortar 1, and an insulating sleeve 216 is sleeved on the outside of the quantitative cooling component 22. A movable semi-ring 217 is fixedly installed on one side of the insulating sleeve 216. The pulling rod 204 is a hexagonal prism, and the guide tube 205 is a circular tube with a regular hexagonal hole in the middle. The fixed semi-ring 214 and the movable semi-ring 217 are spliced into a circular ring to prevent the pulling rod 204 from rotating freely in the guide tube 205, ensuring that the grinding motor 202 is aligned with the center position of the fixed semi-ring 214 and the movable semi-ring 217. A switching tube 218 is fixedly installed in the middle of one side of the movable semi-ring 217, and a switching rod 219 is movably installed inside the switching tube 218. The top of the switching rod 219 is fixedly connected to one end of the steering plate 220, and the other end of the steering plate 220 is movably installed with a clamping tube 221, and a rotating handle 222 is welded to the top of the clamping tube 221.

[0044] The grinding auxiliary assembly 21 includes a grinding head 2101, an upper baffle 2102, a lower baffle 2103, grinding balls 2104, a support spring 2105, an end cap 2106, a rib 2107, and a filling port 2108;

[0045] The bottom end of the mortar rod 201 is fixedly connected to a grinding head 2101, the top of the grinding head 2101 is symmetrically fixedly installed with an upper baffle 2102, and the middle of the grinding head 2101 is symmetrically fixedly installed with a lower baffle 2103. Grinding balls 2104 are placed inside the mortar 1. The distance between the upper baffle 2102 and the lower baffle 2103 is less than the diameter of the grinding balls 2104. The ends and edges of the upper baffle 2102 and the lower baffle 2103 are rounded, and the spatial angle between the upper baffle 2102 and the lower baffle 2103 is 90 degrees, which is convenient for the upper baffle 2 102 and the lower baffle 2103 push the grinding balls 2104 to collide continuously to assist grinding. A support spring 2105 is sleeved on the middle part of the mortar rod 201, and an end cover 2106 is movably sleeved on the top of the mortar rod 201. A rib 2107 is welded on the edge of the end cover 2106. The bottom end of the inner side of the mortar 1 is rounded, and the cross-section of the rib 2107 is a right angle. The rib 2107 and the top of the mortar 1 are connected in a transition fit, which makes it easy to embed the rib 2107 in the mortar 1, and filling holes 2108 are evenly opened on the top surface of the rib 2107.

[0046] The quantitative cooling assembly 22 includes an annular cooling box 2201, a retaining ring 2202, an extrusion hole 2203, an extrusion ring 2204, a cooling screw 2205, a top cover box 2206, a knob 2207, an injection hole 2208, a shielding ring 2209, a right-angle stop 2210, a limit stop 2211 and a toggle rod 2212;

[0047] An annular cooling box 2201 is sleeved on the outside of the mortar 1, and a retaining ring 2202 is fixedly installed inside the annular cooling box 2201. Extrusion holes 2203 are symmetrically opened at the bottom of the retaining ring 2202. An extrusion ring 2204 is movably sleeved on the top of the retaining ring 2202. A cooling screw 2205 is installed on one side of the extrusion ring 2204 through a screw hole. The top of the annular cooling box 2201 is connected to a top cover box 2206. The cross-section of the top cover box 2206 is a hollow right angle with an opening at the bottom. The top of the retaining ring 2202 contacts the inner top surface of the top cover box 2206, and the outer side of the extrusion ring 2204 fits the inner wall of the annular cooling box 2201 close to the outside. The inner side of 204 fits into the outer side of the retaining ring 2202, which is convenient for the extrusion ring 2204 to extrude and add liquid nitrogen. The top of the cooling screw 2205 rotates and passes through the top cover box 2206 and is connected to the knob 2207. The bottom surface of the top cover box 2206 is aligned with the retaining edge 2107 and an injection hole 2208 is opened. The inner edge of the top of the top cover box 2206 is rotated and inlaid with a blocking ring 2209. The bottom end of the blocking ring 2209 is fixedly installed with a right-angle block 2210 corresponding to the injection hole 2208. The top cover box 2206 is provided with a limit block 2211 near the injection hole 2208, and a toggle rod 2212 is fixedly installed on one side of the top surface of the blocking ring 2209.

[0048] The working principle and use process of the present invention are as follows: select an appropriate grinding structure according to the needs of use. When the amount to be ground is small and cooling is not required, take the mortar 1 and place it on a horizontal operating table, put the experimental sample in the mortar 1, put in the grinding head 2101 and the grinding balls 2104, connect the end cover 2106 to the top of the mortar rod 201, take the clamping tube 221, and movably clamp the clamping tube 221 to the top of the mortar rod 201, hold the rotating handle 222 and rotate it, and the grinding head 2101 grinds the experimental sample at the bottom end of the mortar 1. During the grinding process, the upper baffle 2102 and the lower baffle 2103 will alternately hit the grinding balls 2104, and the grinding balls 2104 hit the inside of the mortar 1, vibrating the inside of the mortar 1. The experimental material adhered to the inner wall of the mortar 1 slides down to the bottom end of the mortar 1 under the multiple effects of impact, vibration and gravity, and continues to grind to ensure sufficient grinding;

[0049] When the amount to be ground is small and cooling is required, after the experimental sample, grinding head 2101, grinding balls 2104 and end cover 2106 are placed in the mortar 1, the annular cooling box 2201 is sleeved on the outside of the mortar 1, the outer side of the annular cooling box 2201 is sleeved with the heat insulating sleeve 216, and liquid nitrogen is poured into the annular cooling box 2201, and the top cover box 2206 is quickly installed on the top of the annular cooling box 2201 to slow down the volatilization of the liquid nitrogen, the toggle rod 2212 drives the rotating shielding ring 2209 to remove the right-angle block 2210 blocking the injection hole 2208, and the knob 2207 is turned. The rotating cooling screw 2205 drives the extrusion ring 2204 to move downward, squeezing the liquid nitrogen to flow from the extrusion hole 2203 at the bottom end of the retaining ring 2202, and then discharged from the injection hole 2208 to the top surface of the retaining edge 2107, and flows into the mortar 1 through the filling hole 2108, and the sample is tested. The sample is frozen, and the toggle rod 2212 is pushed again until the right-angle block 2210 is blocked by the limit block 2211 and the injection hole 2208 is closed, which is convenient for freezing the experimental sample next time. With the switching rod 219 in the switching tube 218 as the axis, the steering plate 220 is rotated, the clamping tube 221 is aligned with the top end of the mortar rod 201 and clamped, and the handle 222 is turned to grind. After one grinding is completed, the mortar 1 is pushed out of the annular cooling box 2201, and the equipped new mortar 1 with the experimental sample already placed is put in for grinding again. The quantitative control is convenient for adding liquid nitrogen and saving liquid nitrogen, which improves the convenience of operation. The annular cooling box 2201, the retaining ring 2202, the extrusion ring 2204, the cooling screw 2205, the top cover box 2206, the shielding ring 2209, the right-angle block 2210, the limit block 2211 and the toggle rod 2212 are all made of fiberglass.

[0050] When the amount to be ground is large or there are many types, the samples are quantitatively distributed and placed in each mortar 1 in sequence, and the grinding head 2101, grinding balls 2104 and end caps 2106 are placed in sequence. The mortars 1 are placed in the feeding guide rail 208 on one side, and the limiting groove 4 is embedded in the limiting guide rail 6. The iron strip 5 adsorbs the magnetic strip 7 for temporary limiting. The outer side of the annular cooling box 2201 is sleeved with the heat insulating sleeve 216, and the heat insulating sleeve 216 is close to the fixed half ring 21. 4 is put in, the fixed half ring 214 and the movable half ring 217 are combined into a circle, the suction cup 215 is pressed, the suction cup 215 adsorbs the insulation sleeve 216 on one side, and the insulation sleeve 216 is fixed, pushing the end mortar 1, and the mortars 1 arranged in sequence slide along the feeding guide rail 208 until the end mortar 1 enters the embedded groove 209, and the feeding motor 213 is started. The feeding motor 213 drives the feeding screw 212 to rotate, and pulls the feeding plate 211 to drive the mortars embedded in the groove 209 1 moves up and gradually embeds into the annular cooling box 2201. During this process, the top of the bowl rod 201 will be connected and assembled with the bottom end of the grinding motor 202, and the grinding motor 202 and the horizontal connecting rod 203 will be lifted up, and the pulling rod 204 will rise along the guide tube 205. If cooling and grinding are required, the liquid nitrogen is added in the same way as the above-mentioned liquid nitrogen adding method. The grinding motor 202 is started to drive the bowl rod 201 to rotate and grind. After the grinding is completed, the feeding motor 213 drives the feeding screw 212 to rotate in the opposite direction, and the feeding plate 211 moves down. Under the action of gravity, the feeding motor 213 will also push the bowl rod 201 and the mortar 1 out of the annular cooling box 2201 until the bowl rod 201 returns to the embedding groove 209, and continues to push the mortar 1 at the end, and pushes another mortar 1 to the top surface of the feeding plate 211. Repeat the above steps for grinding, and grind continuously in a semi-automatic manner, which is convenient for processing samples with large quantities or many types, and effectively improves the experimental efficiency.

[0051] Different structures and processing methods can be used according to the needs, such as when the amount to be ground is small, whether liquid nitrogen cooling is required, and when the amount of experimental samples is large or there are many types. When the amount is small, fewer structures are used and it is easy to carry and move. When the amount is large, semi-automatic continuous grinding is convenient to operate and has high grinding efficiency. It is suitable for a variety of different experiments and experimental occasions and has a wider range of applications.

[0052] The grinding auxiliary component 21 relies on the collision of the grinding balls 2104 to improve the grinding effect while reducing adhesion. The quantitative cooling component 22 facilitates the quantitative addition of liquid nitrogen while reducing the consumption of liquid nitrogen, saving materials. It can be coordinated with the switching grinding component 2 according to different experimental needs to achieve better and more efficient grinding results.

[0053] Finally, it should be noted that the above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or substitute equivalents for some of the technical features. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. A molecular biology experimental sample grinder, comprising a mortar (1), characterized in that: A switchable grinding assembly (2) is provided on the outside of the mortar (1), and the switchable grinding assembly (2) comprises a mortar rod (201); A mortar rod (201) is placed inside the mortar (1), and the top end of the mortar rod (201) is movably connected to the output shaft end of the grinding motor (202), and the top end of the grinding motor (202) is connected to one end of the bottom surface of the horizontal connecting rod (203), and the other end of the bottom surface of the horizontal connecting rod (203) is connected to a pull rod (204), and the bottom end of the pull rod (204) is movably connected to a guide tube (205), and the bottom end of the guide tube (205) is fixedly connected to the bottom surface of the support seat (206), and the support seat (206) is provided with a feeding hole (207) at the bottom end of the mortar (1), and both ends of the feeding hole (207) are installed with a feeding guide rail (208). An embedding groove (209) is provided at the bottom end of the feeding hole (207), a lifting hole (210) is provided at the middle portion of the inner side of the feeding hole (207), a feeding plate (211) is movably embedded and installed inside the embedding groove (209), one end of the feeding plate (211) passes through the lifting hole (210) and is connected to a feeding screw (212) through a screw hole, the top end of the feeding screw (212) is connected to the output shaft of the feeding motor (213), the feeding motor (213) is installed on one side of a fixed half ring (214), the fixed half ring (214) is fixedly installed on one side of the top end of the feeding hole (207), and a suction cup (215) is installed on one side of the fixed half ring (214); A grinding auxiliary component (21) is installed inside the mortar (1), a quantitative cooling component (22) is sleeved on the outside of the mortar (1), a heat-insulating sleeve (216) is sleeved on the outside of the quantitative cooling component (22), a movable half-ring (217) is fixedly installed on one side of the heat-insulating sleeve (216), a switching tube (218) is fixedly installed in the middle of one side of the movable half-ring (217), a switching rod (219) is movably installed inside the switching tube (218), the top end of the switching rod (219) is fixedly connected to one end of the steering plate (220), the other end of the steering plate (220) is movably installed with a clamping tube (221), and the top end of the clamping tube (221) is welded with a rotating handle (222); The clamping pipe (221) can be movably clamped with the top of the bowl rod (201); The grinding auxiliary component (21) includes a grinding head (2101); The bottom end of the bowl rod (201) is fixedly connected to a grinding head (2101).

2. A molecular biology experimental sample grinder according to claim 1, characterized in that: An upper baffle (2102) is symmetrically fixedly mounted on the top of the grinding head (2101), a lower baffle (2103) is symmetrically fixedly mounted on the middle of the grinding head (2101), a grinding ball (2104) is placed inside the mortar (1), a support spring (2105) is sleeved on the middle of the mortar rod (201), an end cover (2106) is movably sleeved on the top of the mortar rod (201), a retaining edge (2107) is welded to the edge of the end cover (2106), and a filling hole (2108) is evenly opened on the top surface of the retaining edge (2107).

3. A molecular biology experimental sample grinder according to claim 2, characterized in that: The quantitative cooling assembly (22) comprises an annular cooling box (2201); The outer side of the mortar (1) is sleeved with an annular cooling box (2201), a retaining ring (2202) is fixedly installed inside the annular cooling box (2201), the bottom end of the retaining ring (2202) is symmetrically provided with extrusion holes (2203), the top end of the retaining ring (2202) is movably sleeved with an extrusion ring (2204), one side of the extrusion ring (2204) is installed with a cooling screw (2205) through a screw hole, the top end of the annular cooling box (2201) is abutted against a top cover box (2206), the top end of the cooling screw (2205) rotates and penetrates the top cover box (2206). 6) is connected with a knob (2207), an injection hole (2208) is provided on the bottom surface of the top cover box (2206) aligned with the retaining edge (2107), a blocking ring (2209) is rotatably embedded on the inner edge of the top end of the top cover box (2206), a right-angle block (2210) is fixedly installed at the bottom end of the blocking ring (2209) corresponding to the injection hole (2208), a limit block (2211) is provided near the injection hole (2208) of the top cover box (2206), and a toggle rod (2212) is fixedly installed on one side of the top surface of the blocking ring (2209).

4. The molecular biology experimental sample grinder according to claim 2, characterized in that: The inner bottom end of the mortar (1) is rounded, the cross section of the retaining edge (2107) is a right angle, and the retaining edge (2107) and the top end of the mortar (1) are connected in a transition fit manner.

5. The molecular biology experimental sample grinder according to claim 2, characterized in that: The distance between the upper baffle (2102) and the lower baffle (2103) is smaller than the diameter of the grinding ball (2104), the ends and edges of the upper baffle (2102) and the lower baffle (2103) are rounded, and the spatial angle between the upper baffle (2102) and the lower baffle (2103) is 90°.

6. The molecular biology experimental sample grinder according to claim 2, characterized in that: A motor tray (3) is mounted on one side of the fixed half ring (214), the feeding motor (213) is mounted on the top surface of the motor tray (3), and the output shaft of the feeding motor (213) movably passes through the motor tray (3).

7. The molecular biology experimental sample grinder according to claim 3, characterized in that: The cross-section of the top cover box (2206) is a hollow right angle with an open bottom end, the top end of the retaining ring (2202) contacts the inner top surface of the top cover box (2206), the outer side of the extrusion ring (2204) fits the inner wall of the annular cooling box (2201) close to the outer side, and the inner side of the extrusion ring (2204) fits the outer side of the retaining ring (2202).

8. The molecular biology experimental sample grinder according to claim 3, characterized in that: A limiting groove (4) is provided at the bottom end of the mortar (1), and an iron strip (5) is embedded at the top end of the limiting groove (4). A limiting guide rail (6) is fixedly installed in the middle of the top surface of the feeding guide rail (208) and the feeding plate (211), and a magnetic strip (7) is bonded to the top surface of the limiting guide rail (6).

9. The molecular biology experimental sample grinder according to claim 1, characterized in that: The input ends of the grinding motor (202) and the feeding motor (213) are electrically connected to the output end of the external power supply, respectively. The diameter of the mortar (1) is equal to the diameter of the embedding groove (209), and the top edge of the embedding groove (209) is chamfered.

10. The molecular biology experimental sample grinder according to claim 1, characterized in that: The pulling rod (204) is a hexagonal prism, the conduit (205) is a circular tube with a regular hexagonal hole in the middle, and the fixed half ring (214) and the movable half ring (217) are spliced into a circular ring.

Citation Information

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