A multi-purpose disk and control method thereof

Abstract

This invention provides a multi-purpose disk and its control method. The edge region of the multi-purpose disk is uniformly divided into multiple regions along the circumference. Each region has the same number of receiving positions. Any region can be configured as a sample position, reagent position, antigen position, or dilution position. Multiple actuators surround the multi-purpose disk. The control method includes: acquiring a first position mapping table to a fourth position mapping table; acquiring functional setting information for each region and generating a fifth position mapping table based on the first to fourth position mapping tables; acquiring the position information of each actuator; responding to the task of rotating a target functional position to the location of a target actuator, acquiring the position information of the target functional position based on the fifth position mapping table, and determining the rotation distance of the multi-purpose disk based on the pre-acquired position information of the target actuator; and outputting a corresponding pulse signal based on the rotation distance. This invention solves the problems of limited applicability and inflexible layout of existing automatic analysis devices due to the single-function disk single-use mode.

Description

Technical Field

[0001] The invention belongs to the field of automatic analysis instrument structure optimization, and more specifically, relates to a multi-type purpose disk and a control method thereof. Background Art

[0002] In the related art, a type of automatic analysis device, such as an automatic biochemical analyzer, usually needs to be applied to functional disks such as sample disks, reagent disks, antigen disks, and dilution disks. However, at present, the functional disks of the above-mentioned automatic analysis devices are all single-disc single-use mode, that is, a functional disk can only be used as one of the sample disk, reagent disk, antigen disk, and dilution disk. This single-disc single-use mode mainly leads to the following two problems:

[0003] First, the existing automatic analysis device needs to be applied to at least a sample disk and a reagent disk. The single-disc single-use mode requires at least two functional disks to be set up, which makes the volume of the automatic analysis device larger, and further causes its scope of application to be limited by its own volume.

[0004] 2. Inability to flexibly layout: When a certain type of function disk is not needed at the current stage, the function disk cannot be replaced with other types of function disks due to the inherent layout, which cannot meet the customer's personalized actual needs and causes a waste of resources. Summary of the invention

[0005] In view of this, the present invention provides a multi-purpose disk and a control method thereof.

[0006] According to a first aspect of the present invention, there is provided a multi-purpose disk, the multi-purpose disk being applied to an automatic analysis device, the automatic analysis device comprising a controller and a stepper motor, the stepper motor being used to drive the multi-purpose disk to rotate along a fixed axis under the control of the controller;

[0007] The edge area of ​​the multi-purpose disk is evenly divided into multiple areas along the circumferential direction, each area is provided with multiple accommodation positions of the same number, and all the accommodation positions are evenly distributed in the circumferential direction;

[0008] Any area is configured to be used as a sample position area, a reagent position area, an antigen position area or a dilution position area, wherein one sample position is provided for every X1 accommodation positions in the sample position area, one reagent position is provided for every X2 accommodation positions in the reagent position area, one antigen position is provided for every X3 accommodation positions in the antigen position area, and each accommodation position in the dilution position area serves as a dilution position;

[0009] The automatic analysis device further comprises a plurality of actuators distributed around the multi-purpose disk, wherein the types of the actuators include a sample needle, a reagent needle, a cleaning arm and a stirring arm.

[0010] Optionally, if the at least two areas of the multi-purpose disc are used as dilution areas, the at least two areas are continuous areas.

[0011] Optionally, one sample position is provided for every three accommodation positions in the sample position area, and the sample position is arranged at the last accommodation position among the corresponding three accommodation positions;

[0012] and / or, one reagent position is provided for every three receiving positions in the reagent position area and the reagent position is arranged at the last receiving position among the corresponding three receiving positions;

[0013] And / or, one antigenic site is provided for every three accommodation sites in the antigenic site region and the antigenic site is arranged in the last accommodation site of the corresponding three accommodation sites.

[0014] Optionally, all the accommodation positions are distributed at equal intervals in the circumferential direction;

[0015] Alternatively, there is no gap between any two adjacent accommodation locations among all the accommodation locations.

[0016] According to a second aspect of the present invention, there is provided a control method for any of the above-mentioned multi-purpose disks, the control method being applied to the controller and comprising the following steps:

[0017] Obtain a first position mapping table, a second position mapping table, a third position mapping table, and a fourth position mapping table, wherein the first position mapping table provides a position mapping relationship between sample positions and receiving positions when all regions are used as sample position regions, the second position mapping table provides a position mapping relationship between reagent positions and receiving positions when all regions are used as reagent position regions, the third position mapping table provides a position mapping relationship between antigen positions and receiving positions when all regions are used as antigen position regions, and the fourth position mapping table provides a position mapping relationship between dilution positions and receiving positions when all regions are used as dilution position regions;

[0018] Acquire function setting information of each area, and call the first position mapping table, the second position mapping table, the third position mapping table and the fourth position mapping table to generate a fifth position mapping table, wherein the fifth position mapping table provides a position mapping relationship between a function bit and an accommodation bit of each area under a corresponding function setting;

[0019] Acquiring position information of each actuator, wherein the position of each actuator is represented by the position of the accommodation position;

[0020] In response to a task of rotating a target function bit to a position where a target actuator is located, obtaining position information of the target function bit according to the fifth position mapping table, and determining a rotation distance of the multi-purpose disk according to the position information of the target function bit and pre-acquired position information of the target actuator;

[0021] A corresponding pulse signal is output according to the rotation distance.

[0022] Optionally, the control further includes:

[0023] After the corresponding pulse signal is output according to the rotation distance, the position information of each actuator is updated.

[0024] The beneficial effects of the present invention are:

[0025] The multi-purpose disc of the present invention is evenly divided into multiple areas along the circumferential direction at its edge area, each area is provided with multiple accommodating positions of the same number, and all the accommodating positions are evenly distributed in the circumferential direction; any area is configured to be used as a sample position area, a reagent position area, an antigen position area or a dilution position area, wherein one sample position is provided for every X1 accommodating positions in the sample position area, one reagent position is provided for every X2 accommodating positions in the reagent position area, one antigen position is provided for every X3 accommodating positions in the antigen position area, and each accommodating position in the dilution position area serves as a dilution position.

[0026] The control method of the multi-type purpose disk of the present invention obtains a fifth position mapping table for providing a position mapping relationship between the function bit and the accommodation bit of each area under the corresponding function setting according to the function setting information of each area and the first position mapping table to the fourth position mapping table; when executing the task of rotating the target function bit to the position of the target actuator, the position information of the target function bit is obtained according to the fifth position mapping table, and the rotation distance of the multi-type purpose disk is determined according to the position information of the target function bit and the pre-acquired position information of the target actuator, so as to drive it to perform corresponding rotation.

[0027] Based on the above, it can be seen that by adopting the multi-type purpose disk of the present invention in combination with the corresponding control method, it is possible to realize multiple uses of a single functional disk, thereby effectively solving the problem that the existing automatic analysis device is limited in its applicable scenarios and cannot be flexibly arranged due to the single-function disk single-use mode.

[0028] Other features and advantages of the present invention will be described in detail in the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] The present invention may be better understood by referring to the following description taken in conjunction with the accompanying drawings, in which the same or similar reference numerals are used throughout the drawings to represent the same or similar components.

[0030] Figure 1 A schematic diagram showing the layout of a multi-type purpose tray according to an embodiment of the present invention is shown;

[0031] Figure 2A flowchart showing a method for controlling a multi-type purpose disk according to an embodiment of the present invention is shown;

[0032] Figure 3 A test flow chart according to an embodiment of the present invention is shown. DETAILED DESCRIPTION

[0033] In order to enable those skilled in the art to more fully understand the technical solution of the present invention, the exemplary embodiments of the present invention will be described in more comprehensive and detailed in conjunction with the accompanying drawings below. Obviously, the one or more embodiments of the present invention described below are only one or more of the specific ways in which the technical solution of the present invention can be implemented, and are not exhaustive. It should be understood that other ways belonging to a general inventive concept can be used to implement the technical solution of the present invention, and should not be limited by the exemplary embodiments described. Based on one or more embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without making creative work should fall within the scope of protection of the present invention.

[0034] Example: Figure 1 FIG. 2 is a schematic diagram showing the layout of a multi-purpose disk according to an embodiment of the present invention. Figure 1 The multi-purpose disk of the embodiment of the present invention is applied to an automatic analysis device, which includes a controller and a stepper motor, and the stepper motor is used to drive the multi-purpose disk to rotate along a fixed axis under the control of the controller;

[0035] The edge area of ​​the multi-purpose tray is evenly divided into eleven areas 100 along the circumferential direction, each area 100 is provided with fifteen accommodation positions 110, and all the accommodation positions 110 are evenly distributed in the circumferential direction;

[0036] Each area 100 is configured to be used as a sample area 200, a reagent area 300, an antigen area 400 or a dilution area 500;

[0037] Among them, one sample position 210 is provided for every three receiving positions in the sample position area 200 and the sample position 210 is disposed at the last receiving position 110 among the corresponding three receiving positions 110;

[0038] A reagent position 310 is provided for every three receiving positions in the reagent position area 300 and the reagent position 310 is disposed at the last receiving position 110 among the corresponding three receiving positions 110;

[0039] An antigen site 410 is provided for every three accommodation sites in the antigen site region 400 and the antigen site 410 is disposed in the last accommodation site 110 of the corresponding three accommodation sites 110 ;

[0040] Each accommodation position 110 in the dilution position area 500 serves as a dilution position 510;

[0041] The automatic analysis device further includes a plurality of actuators distributed around the multi-purpose disk, including a first sample needle 610 , a second sample needle 620 , a reagent needle disposed on a reagent arm 630 , a cleaning arm 640 , and a stirring arm 650 .

[0042] Furthermore, in the embodiment of the present invention, if at least two areas 100 of the multi-purpose disc are used as dilution areas 500, the at least two areas 100 are continuous areas;

[0043] All the receiving locations 110 are distributed closely and without spacing in the circumferential direction.

[0044] Accordingly, based on the multi-type purpose disk in the embodiment of the present invention, the embodiment of the present invention further proposes a control method for the multi-type purpose disk.

[0045] Figure 2 The flowchart of the control method of the multi-purpose disk according to the embodiment of the present invention is shown. Figure 2 The control method of the multi-purpose disk according to the embodiment of the present invention is applied to the controller, and specifically comprises the following steps:

[0046] Step S100, obtaining a first position mapping table, a second position mapping table, a third position mapping table and a fourth position mapping table, wherein the first position mapping table provides a position mapping relationship between sample positions and receiving positions when all regions are used as sample position regions, the second position mapping table provides a position mapping relationship between reagent positions and receiving positions when all regions are used as reagent position regions, the third position mapping table provides a position mapping relationship between antigen positions and receiving positions when all regions are used as antigen position regions, and the fourth position mapping table provides a position mapping relationship between dilution positions and receiving positions when all regions are used as dilution position regions;

[0047] Step S200, obtaining function setting information of each area, and calling the first position mapping table, the second position mapping table, the third position mapping table and the fourth position mapping table to generate a fifth position mapping table, wherein the fifth position mapping table provides a position mapping relationship between a function bit and an accommodation bit of each area under a corresponding function setting;

[0048] Step S300, obtaining position information of each actuator, wherein the position of each actuator is represented by the position of the accommodation position;

[0049] Step S400, in response to the task of rotating the target function bit to the position of the target actuator, obtaining the position information of the target function bit according to the fifth position mapping table, and determining the rotation distance of the multi-type purpose disk according to the position information of the target function bit and the pre-acquired position information of the target actuator;

[0050] Step S500: output a corresponding pulse signal according to the rotation distance, and update the position information of each actuator.

[0051] Specifically, the control method of the multi-purpose disk according to the embodiment of the present invention is described in more detail below:

[0052] The position 1 of area 1 of the multi-purpose disk is respectively set as the sample position A0, the reagent position B0, the antigen position C0 and the dilution position D0, and the sample position interval position A1, the reagent position interval position B1, the antigen position interval position C1 and the dilution position interval position D1 are set, wherein the sample position interval position A1, the reagent position interval position B1 and the antigen position interval position C1 are all 3, and the dilution position interval position D1 is 1;

[0053] Set position 1 of the area corresponding to the sample needle S1 as position Ps1 of the sample needle S1. There are 11 areas in total on the whole plate, with 15 positions in each area, corresponding to a total of 11*15=165 positions. At this time, the sample needle S2, the reagent needle R, the stirring arm M3 and the cleaning arm W2 respectively correspond to different positions in different areas. According to the predetermined relative position relationship between the sample needle S1 and the sample needle S2, the reagent needle R, the stirring arm M3 and the cleaning arm W2, the position Ps2 of the sample needle S2, the position Pr of the reagent needle R, the position Pm of the stirring arm M3 and the positions Pc1~Pc5 of the five cleaning needles of the cleaning arm W2 can be calculated.

[0054] The first position mapping table Fa, the second position mapping table Fb, the third position mapping table Fc and the fourth position mapping table Fd are generated according to the above information, and the fifth position mapping table Fe is generated according to the function setting information of each area, specifically:

[0055] According to the sample bit position A0 and the sample bit interval position A1, it can be concluded that Fa[1-3] is A0, Fa[4-6] is A0+A1, and Fa[n] is A0+A1*((n-1) / 3). When the result of (n-1) / 3 is not an integer, it is rounded down to calculate all the positions of the first position mapping table Fa[1-165];

[0056] According to the reagent position B0 and the reagent position interval position B1, it can be concluded that Fb[1-3] is B0, Fb[4-6] is B0+B1, and Fb[n] is B0+B1*((n-1) / 3). When the result of (n-1) / 3 is not an integer, it is rounded down to calculate all the positions of the second position mapping table Fb[1-165];

[0057] According to the antigen site position C0 and the antigen site interval position C1, it can be concluded that Fc[1-3] is C0, Fc[4-6] is C0+C1, ​​and Fc[n] is C0+C1*((n-1) / 3). When the result of (n-1) / 3 is not an integer, it is rounded down to calculate all the positions of the third position mapping table Fc[1-165];

[0058] According to the dilution position D0 and the dilution interval position D1, it can be concluded that Fd[1] is D0, Fd[2] is D0+D1, and Fd[n] is D0+D1*(n-1), thereby calculating all positions of the fourth position mapping table Fd[1-165];

[0059] After obtaining the first position mapping table Fa, the second position mapping table Fb, the third position mapping table Fc and the fourth position mapping table Fd, the function types corresponding to the 11 areas are filled into the fifth position mapping table Fe. When area 1 is the sample position area, Fe[1~15]=Fa[1~15], when area 2 is the reagent position area, Fe[16~30]=Fb[16~30], and so on to generate the fifth position mapping table Fe[1~165].

[0060] Figure 3 A test flow chart of an embodiment of the present invention is shown, referring to Figure 3 , based on the fifth position mapping table Fe, the following test process can be implemented:

[0061] Step 1, before starting the test, obtain the fifth position mapping table Fe, the position Ps1 of the sample needle S1, the position Ps2 of the sample needle S2, the position Pr of the reagent needle R, the position Pm of the stirring arm M3 and the positions Pc1 to Pc5 of the five cleaning needles of the cleaning arm W2, where the position range is 1 to 165;

[0062] Step 2: After the information is obtained, each cycle is repeated according to steps 3 to 9 until the test is stopped;

[0063] Step 3, determine whether the reagent needle R needs to go to the multi-purpose disc to absorb the reagent. If so, obtain the position m of the area n where the reagent needs to be absorbed, convert it into the position Pnext of (n-1)*15+m*3, and then use Fe[Pnext]-Fe[Pr] to obtain the distance that the multi-purpose disc needs to rotate and rotate it. After the rotation is completed, the reagent needle R absorbs the reagent; if not, execute step 4;

[0064] Step 4, determine whether the sample needle S2 needs to go to the multi-purpose disk to suck or spit out samples. If so, obtain the area n position m where the sample needs to be sucked or spit out, and convert it into position Pnext1 as (n-1)*15+m*3 or position Pnext2 as (n-1)*15+m, where Pnext1 represents that the area is a sample position area, and Pnext2 represents that the area is a dilution position area. Then use Fe[Pnext1]-Fe[Ps2] or Fe[Pnext2-Fe[Ps2] to obtain the distance that the multi-purpose disk needs to rotate and rotate. After the rotation is completed, the sample needle S2 sucks or spits out the sample;

[0065] Step 5, determine whether the sample needle S1 needs to go to the multi-purpose disk to suck or spit out samples. If so, obtain the area n position m where the sample needs to be sucked or spit out, and convert it into position Pnext1 as (n-1)*15+m*3 or position Pnext2 as (n-1)*15+m, where Pnext1 represents that the area is a sample position area, and Pnext2 represents that the area is a dilution position area. Then use Fe[Pnext1]-Fe[Ps1] or Fe[Pnext2-Fe[Ps1] to obtain the distance that the multi-purpose disk needs to rotate and rotate. After the rotation is completed, the sample needle S1 sucks or spits out the sample; if not, execute step 5;

[0066] Step 6 and steps 3 to 5 will only execute one process per cycle. When the multi-function application disk determines the current information, the positions except Pr are updated when the reagent needle R is currently adding samples. The updated position is the difference between the current recorded position value plus the current position value minus Pnext, and finally Pr is updated to Pnext; the same applies to the sample needle S1, sample needle S2, stirring arm M3 and cleaning arm W2;

[0067] Step 7, then determine whether the position under Fe[Pm] corresponding to the stirring arm M3 needs stirring, and if stirring is needed, perform stirring action; if the judgment results of steps 3 to 5 are all no, then find out whether there is a position that needs stirring, if so, convert the position Pnext into (n-1)*15+m, then use Fe[Pnext]-Fe[Pm] to obtain the distance that the multi-type purpose disk needs to rotate and rotate, then perform stirring action, and update all positions according to step 6 at the same time;

[0068] Step 8. Finally, determine whether the position of Fe[Pc1~Pc5] corresponding to the cleaning arm W3 satisfies the cleaning process. If so, perform the cleaning action. If the judgment results of steps 3~5 and 7 are all no, find out whether there is a position that needs to be cleaned. The cleaning rule is to find the position that needs to be cleaned in the first step. If not, find the position that needs to be cleaned in the second step, and so on until all five positions are found. If there is, convert the position Pnext to (n-1)*15+m, and then use Fe[Pnext]-Fe[Pc1 / Pc2 / Pc3 / Pc4 / Pc5] to obtain the distance that the multi-type purpose disk needs to rotate and rotate, then perform the cleaning action, and update all positions according to step 6 at the same time;

[0069] Step 9: After completing the above steps, proceed to a new cycle.

[0070] The use of the multi-type purpose disk of the embodiment of the present invention in combination with the corresponding control method can effectively save the space of the instrument, support flexible layout, and solve the personalized needs of customers. At the same time, it ensures the accuracy of the functional needle in the multi-type purpose disk and the accuracy and reliability of the test results.

[0071] Although one or more embodiments of the present invention are described above, it should be known to those skilled in the art that the present invention can be implemented in any other form without departing from its subject matter and scope. Therefore, the embodiments described above are illustrative rather than restrictive, and many modifications and substitutions are obvious to those skilled in the art without departing from the spirit and scope of the present invention as defined in the appended claims.

Claims

1. A multi-purpose tray, characterized in that: Applicable to an automatic analysis device, the automatic analysis device comprises a controller and a stepper motor, the stepper motor is used to drive the multi-purpose disk to rotate along a fixed axis under the control of the controller; The edge area of ​​the multi-purpose disk is evenly divided into multiple areas along the circumferential direction, each area is provided with multiple accommodation positions of the same number, and all the accommodation positions are evenly distributed in the circumferential direction; Any area is configured to be used as a sample position area, a reagent position area, an antigen position area or a dilution position area, wherein one sample position is provided for every X1 accommodation positions in the sample position area, one reagent position is provided for every X2 accommodation positions in the reagent position area, one antigen position is provided for every X3 accommodation positions in the antigen position area, and each accommodation position in the dilution position area serves as a dilution position; The automatic analysis device further comprises a plurality of actuators distributed around the multi-purpose disk, wherein the types of the actuators include a sample needle, a reagent needle, a cleaning arm and a stirring arm.

2. The multi-purpose tray according to claim 1, characterized in that: If the at least two areas of the multi-purpose disk are used as dilution areas, the at least two areas are continuous areas.

3. The multi-purpose tray according to claim 1, characterized in that: A sample position is provided for every three receiving positions in the sample position area and the sample position is arranged at the last receiving position among the corresponding three receiving positions; and / or, one reagent position is provided for every three receiving positions in the reagent position area and the reagent position is arranged at the last receiving position among the corresponding three receiving positions; And / or, one antigenic site is provided for every three accommodation sites in the antigenic site region and the antigenic site is arranged in the last accommodation site of the corresponding three accommodation sites.

4. The multi-purpose tray according to claim 1, characterized in that: All the accommodation positions are evenly spaced in the circumferential direction; Alternatively, there is no gap between any two adjacent accommodation locations among all the accommodation locations.

5. The control method of the multi-purpose disk according to any one of claims 1 to 4, characterized in that: applied to the controller; The control method comprises: Obtain a first position mapping table, a second position mapping table, a third position mapping table, and a fourth position mapping table, wherein the first position mapping table provides a position mapping relationship between sample positions and receiving positions when all regions are used as sample position regions, the second position mapping table provides a position mapping relationship between reagent positions and receiving positions when all regions are used as reagent position regions, the third position mapping table provides a position mapping relationship between antigen positions and receiving positions when all regions are used as antigen position regions, and the fourth position mapping table provides a position mapping relationship between dilution positions and receiving positions when all regions are used as dilution position regions; Acquire function setting information of each area, and call the first position mapping table, the second position mapping table, the third position mapping table and the fourth position mapping table to generate a fifth position mapping table, wherein the fifth position mapping table provides a position mapping relationship between a function bit and an accommodation bit of each area under a corresponding function setting; Acquiring position information of each actuator, wherein the position of each actuator is represented by the position of the accommodation position; In response to a task of rotating a target function bit to a position where a target actuator is located, obtaining position information of the target function bit according to the fifth position mapping table, and determining a rotation distance of the multi-purpose disk according to the position information of the target function bit and pre-acquired position information of the target actuator; A corresponding pulse signal is output according to the rotation distance.

6. The control method according to claim 5, characterized in that: Also includes: After the corresponding pulse signal is output according to the rotation distance, the position information of each actuator is updated.

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