A multi-channel pipette with waste tip recovery function

Abstract

The present invention relates to a multichannel pipette with a discarded suction tip recovery function, comprising a multichannel pipette body, a multichannel suction tip supply and collection device with suction tip supply and recovery functions, and a supply and collection device driving mechanism, the supply and collection device driving mechanism is arranged beside the multichannel pipette body, the multichannel suction tip supply and collection device is installed at the lower end of the supply and collection device driving mechanism and moves up and down under the drive of the supply and collection device, the multichannel suction tip supply and collection device comprises a supply and collection device housing, a multichannel suction tip storage bin slider and a storage bin driving mechanism, the multichannel suction tip storage bin slider is slidably installed in the supply and collection device housing and slides forward and backward under the drive of the storage bin driving mechanism, the supply and collection device housing is provided with n suction tip outlet through holes that are connected up and down, the multichannel suction tip storage bin slider is provided with m×n suction tip supply channels, wherein the rear (m‑1)×n suction tips are provided, and a disengagement pin is provided on the upper inner side of the suction tip supply channel. The multichannel pipette can realize automatic loading and unloading and recovery of multiple suction tips, which can not only improve the pipetting efficiency, but also avoid the waste suction tips from polluting the environment.

Description

Technical Field

[0001] The invention relates to the field of pipettes, and in particular to a multi-channel pipette with a waste pipette tip recovery function. Background Art

[0002] A pipette is a common tool that can accurately transfer liquid samples and is widely used in the fields of biology, medicine, chemistry, and materials. During the use of an existing pipette, after the transfer is completed, the control button is pressed to remove the used disposable tip. However, since the liquids transferred are mostly chemical and biological reagents, if the disposable tip is directly discarded after use, the residual liquid on the tip will pollute the environment. Therefore, it is necessary to recycle the used discarded tips to avoid environmental pollution. Summary of the invention

[0003] The object of the present invention is to provide a multi-channel pipette with a waste tip recovery function, which can realize automatic loading and unloading and recovery of multiple tips, which can not only improve the pipetting efficiency, but also avoid the waste tips from polluting the environment.

[0004] In order to achieve the above-mentioned purpose, the technical solution adopted by the present invention is: a multi-channel pipette with a waste tip recovery function, including a multi-channel pipette body, a multi-channel tip supply and collection device with a tip supply and recovery function, and a supply and collection device driving mechanism, the supply and collection device driving mechanism is arranged on the side of the multi-channel pipette body, the multi-channel tip supply and collection device is fixedly installed at the lower end of the supply and collection device driving mechanism and moves up and down under the drive of the supply and collection device, the multi-channel tip supply and collection device includes a supply and collection device housing, a multi-channel tip storage bin slider and a storage bin driving mechanism, the multi-channel tip storage bin slider is slidably installed on The supply and receiving device is inside the shell and slides back and forth under the drive of the storage bin driving mechanism. The supply and receiving device shell is provided with n pipette tip outlet through holes which pass through from top to bottom in parallel. The multi-channel pipette tip storage bin slider is provided with m×n pipette tip supply channels in an array, wherein the rear (m-1)×n pipette tip supply channels are all provided with pipette tips. In the initial state, the n pipette tip supply channels in the front row are directly opposite to the n pipette tip outlet through holes, and the n pipette piston cylinders at the lower part of the multi-channel pipette body pass through the corresponding pipette tip outlet through holes and pipette tip supply channels, and a release pin is provided on the inner upper part of each pipette tip supply channel.

[0005] Further, when the supply and receiving device driving mechanism drives the multi-channel tip supply and receiving device to move downward, the multi-channel pipette body moves upward relative to the multi-channel tip supply and receiving device until the pipette piston cylinder and the pipette nozzle at the lower part of the multi-channel pipette body leave the multi-channel tip supply and receiving device, at which time the storage bin driving mechanism drives the multi-channel tip storage bin slider to slide forward, so that the next row of n tip supply channels with clean tips are directly opposite to the n tip outlet through holes; then the multi-channel tip supply and receiving device moves upward, so that the n clean tips are correspondingly covered on the pipette nozzles at the lower ends of the n pipette piston cylinders; After completing the pipetting work, when the supply and collection device driving mechanism drives the multi-channel tip supply and collection device to move downward again, the multi-channel pipette body moves upward relative to the multi-channel tip supply and collection device until the upper end of the tip on the pipette nozzle hits the disengagement pin, and the tip is clamped by the disengagement pin to separate it from the pipette nozzle, and the pipette piston cylinder and the pipette nozzle leave the multi-channel tip supply and collection device and the used and discarded tips are recovered in the multi-channel tip storage bin slider; at this time, the storage bin driving mechanism drives the multi-channel tip storage bin slider to slide forward again, so that the next row of n tip supply channels with clean tips are opposite to the n tip outlet through holes; then the multi-channel tip supply and collection device is moved upward, so that the n clean tips are correspondingly covered on the pipette nozzles at the lower ends of the n pipette piston cylinders.

[0006] Furthermore, the storage bin driving mechanism includes a first motor, a pulley and a belt transmission belt, the first motor is mounted on the supply and receiving device housing, and the output end of the first motor is connected to the pulley to drive the pulley to rotate, the belt transmission belt is wound around the pulley and connected to the multi-channel suction head storage bin slider to drive the multi-channel suction head storage bin slider to slide forward and backward through the forward and reverse rotation of the pulley.

[0007] Furthermore, the storage bin driving mechanism is an electric cylinder mechanism, which is mounted on the supply and receiving device housing, and an output end of which is connected to a multi-channel suction head storage bin slider to drive the multi-channel suction head storage bin slider to slide back and forth.

[0008] Furthermore, the supply and receiving device driving mechanism is an electrically controlled driving mechanism, which includes a mounting frame, a power supply battery, a second motor, a screw rod, an electric push rod, a push rod and a motor control button. The mounting frame is fixedly connected to the side of the multi-channel pipette body, the power supply battery and the second motor are fixedly installed in the mounting frame, and the output end of the second motor is downwardly connected to the screw rod to drive the screw rod to rotate, the lower part of the screw rod cooperates with the electric push rod to drive the electric push rod to move up and down through the forward and reverse rotation of the screw rod, the lower end of the electric push rod is fixedly connected to the upper end of the push rod, and the lower end of the push rod is fixedly connected to the multi-channel suction tip supply and receiving device; the power supply battery supplies power to the second motor, and the motor control button is connected to the control end of the second motor to control the start and stop and forward and reverse rotation of the second motor.

[0009] Furthermore, the multi-channel pipette body mainly includes a shell, a control button, a counter, a volume adjustment button, a volume display window, a pipette piston rod and a pipette piston cylinder.

[0010] Furthermore, the lower part of the multi-channel pipette body includes a piston mechanism housing, a driving rod, a piston push plate, n pipette piston rods and n pipette piston cylinders, the n pipette piston cylinders are installed side by side in the piston mechanism housing and pass downward through the piston mechanism housing, the lower end of the driving rod is fixedly connected to the upper part of the piston push plate, the lower part of the piston push plate is fixedly connected to the n pipette piston rods arranged side by side in the piston mechanism housing, the n pipette piston rods are respectively matched with corresponding pipette piston cylinders, and the multi-channel pipette body drives the piston push plate and the n pipette piston rods thereunder to move up and down through the driving rod.

[0011] Compared with the prior art, the present invention has the following beneficial effects: the present invention provides a multi-channel pipette with a waste tip recovery function, which can not only provide multiple tips at the same time and automatically install them on the pipette nozzle through the innovative design of the multi-channel tip supply and collection device, thereby improving the pipetting efficiency, but also can recover the used waste tips for centralized treatment, thereby avoiding the waste tips from polluting the environment. Therefore, the present invention has strong practicality and broad application prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 A front view of a multi-channel pipette according to an embodiment of the present invention; Figure 2 A partially cut-away side view of a multi-channel pipette according to an embodiment of the present invention; Figure 3 A partial cross-sectional view of a multi-channel pipette in an initial state in an embodiment of the present invention; Figure 4 is a partial cross-sectional view of the multi-channel pipette when the electric-controlled drive mechanism is partially extended in an embodiment of the present invention; Figure 5 is a partial cross-sectional view of the multi-channel pipette when the electric-controlled drive mechanism is fully extended in an embodiment of the present invention; Figure 6 is a partial cross-sectional view of the multi-channel pipette when the electric-controlled drive mechanism is partially retracted in an embodiment of the present invention; Figure 7 is a partial cross-sectional view of the multi-channel pipette when the electric-controlled drive mechanism is fully retracted in an embodiment of the present invention; Figure 8 It is a partial cross-sectional view of the multi-channel pipette when the electric-controlled drive mechanism is fully extended again in the embodiment of the present invention.

[0013] In the figure: 3-control button, 4-volume adjustment button, 5-volume display window, 13-pipette tip, 16-rubber ring, 17-detachment pin, 18-pipette piston cylinder, 20-multi-channel pipette body, 21-multi-channel pipette body lower part, 22-multi-channel tip storage bin slider, 23-multi-channel tip supply and collection device, 24-supply and collection device housing, 25-pipette nozzle, 26-first motor, 27-pulley, 28-belt drive belt, 29-fixing bolt, 30-elevator, 32-electric push rod, 33-screw, 34-second motor, 35-power supply battery, 36-motor control button, 37-discarded pipette tip. DETAILED DESCRIPTION

[0014] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0015] It should be noted that the following detailed descriptions are exemplary and are intended to provide further explanation of the present application. Unless otherwise specified, all technical and scientific terms used herein have the same meanings as those commonly understood by those skilled in the art to which the present application belongs.

[0016] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.

[0017] like Figure 1-8 As shown, the present embodiment provides a multi-channel pipette with a waste tip recovery function, including a multi-channel pipette body 20, a multi-channel tip supply and recovery device 23 with a tip supply and recovery function, and a supply and recovery device driving mechanism, wherein the supply and recovery device driving mechanism is arranged beside the multi-channel pipette body 20, the multi-channel tip supply and recovery device 23 is fixedly installed at the lower end of the supply and recovery device driving mechanism and moves up and down under the drive of the supply and recovery device driving mechanism, the multi-channel tip supply and recovery device 23 includes a supply and recovery device housing 24, a multi-channel tip storage bin slider 22 and a storage bin driving mechanism, and the multi-channel tip storage bin slider 22 is slidably installed on the supply and recovery device The multi-channel pipette storage bin slides forward and backward in the outer shell 24 and is driven by the storage bin driving mechanism. The supply and receiving device outer shell 24 is provided with n pipette tip outlet through holes which pass through from top to bottom in a side-by-side manner. The multi-channel pipette tip storage bin slider 22 is provided with m×n pipette tip supply channels in an array, wherein the rear (m-1)×n pipette tip supply channels are each provided with a pipette tip 13. In the initial state, the n pipette tip supply channels in the front row are directly opposite to the n pipette tip outlet through holes, and the n pipette piston cylinders at the lower part of the multi-channel pipette body pass through the corresponding pipette tip outlet through holes and pipette tip supply channels, and a disassembly pin 17 is provided on the inner upper part of each pipette tip supply channel.

[0018] When the supply and receiving device driving mechanism drives the multi-channel tip supply and receiving device 23 to move downward, the multi-channel pipette body 20 moves upward relative to the multi-channel tip supply and receiving device 23 until the pipette piston cylinder and the pipette nozzle 25 at the lower part of the multi-channel pipette body 20 leave the multi-channel tip supply and receiving device 23. At this time, the storage bin driving mechanism drives the multi-channel tip storage bin slider 22 to slide forward, so that the next row of n tip supply channels with clean tips are opposite to the n tip outlet through holes; then the multi-channel tip supply and receiving device 23 moves upward, so that the n clean tips are correspondingly covered on the pipette nozzles 25 at the lower ends of the n pipette piston cylinders.

[0019] After completing the pipetting work, when the supply and collection device driving mechanism drives the multi-channel tip supply and collection device 23 to move downward again, the multi-channel pipette body 20 moves upward relative to the multi-channel tip supply and collection device 23 until the upper end of the tip on the pipette nozzle 25 hits the disengagement pin, and the tip is clamped by the disengagement pin 17 to separate it from the pipette nozzle 25, and the pipette piston cylinder and the pipette nozzle 25 leave the multi-channel tip supply and collection device 23 and the used and discarded tips 37 are recovered in the multi-channel tip storage bin slider 22; at this time, the storage bin driving mechanism drives the multi-channel tip storage bin slider 22 to slide forward again, so that the next row of n tip supply channels with clean tips are opposite to the n tip outlet through holes; then the multi-channel tip supply and collection device 23 is moved upward, so that the n clean tips are correspondingly covered on the pipette nozzles at the lower ends of the n pipette piston cylinders.

[0020] In this embodiment, the storage bin driving mechanism includes a first motor 26, a pulley 27 and a belt transmission belt 28. The first motor 26 is installed on the supply and storage device housing 24, and the output end of the first motor 26 is connected to the pulley 27 to drive the pulley 27 to rotate. The belt transmission belt 28 is wound around the pulley 27 and connected to the multi-channel suction head storage bin slider 22 to drive the multi-channel suction head storage bin slider to slide forward and backward through the forward and reverse rotation of the pulley.

[0021] In other embodiments of the present invention, the storage bin driving mechanism may also be an electric cylinder mechanism, which is mounted on the supply and receiving device housing, and whose output end is connected to the multi-channel suction tip storage bin slider to drive the multi-channel suction tip storage bin slider to slide back and forth.

[0022] In the present embodiment, the supply and receiving device driving mechanism is an electrically controlled driving mechanism, which includes a mounting frame, a power supply battery 35, a second motor 34, a screw rod 33, an electric push rod 32, a push rod 30 and a motor control button 36. The mounting frame is fixedly connected to the side of the multi-channel pipette body 20, the power supply battery 35 and the second motor 34 are fixedly installed in the mounting frame, and the output end of the second motor 34 is downwardly connected to the screw rod 33 to drive the screw rod to rotate, the lower part of the screw rod 33 cooperates with the electric push rod 32 to drive the electric push rod to move up and down through the forward and reverse rotation of the screw rod, the lower end of the electric push rod 32 is fixedly connected to the upper end of the push rod 30, and the lower end of the push rod 30 is fixedly connected to the multi-channel suction head supply and receiving device 23 through a fixing bolt 29; the power supply battery 35 supplies power to the second motor 34, and the motor control button 36 is connected to the control end of the second motor 34 to control the start and stop and forward and reverse rotation of the second motor.

[0023] In this embodiment, the multi-channel pipette body 20 mainly includes a housing, a control button 3, a counter, a volume adjustment button 4, a volume display window 5, a pipette piston rod and a pipette piston cylinder.

[0024] In this embodiment, the pipette body is a multi-channel pipette body, and the lower part 21 of the multi-channel pipette body includes a piston mechanism housing, a driving rod, a piston push plate, n pipette piston rods and n pipette piston cylinders, the n pipette piston cylinders are installed side by side in the piston mechanism housing and pass downward through the piston mechanism housing, the lower end of the driving rod is fixedly connected to the upper part of the piston push plate, the lower part of the piston push plate is fixedly connected to the n pipette piston rods arranged side by side in the piston mechanism housing, the n pipette piston rods are respectively matched with corresponding pipette piston cylinders, and the multi-channel pipette body drives the piston push plate and the n pipette piston rods thereunder to move up and down through the driving rod.

[0025] When the multichannel pipette is working, the motor control button 36 is pressed, and the second motor 34 drives the screw rod 33 to rotate, and the push rod 30 and the multichannel suction head supply and receiving device 23 connected thereto move downward to separate from the pipette piston cylinder. When the multichannel suction head supply and receiving device 23 drops to leave the pipette nozzle 25, the storage bin driving mechanism drives the multichannel suction head storage bin slide block 22 to slide forward, so that the n suction head supply channels with clean suction heads in the next row are moved to the bottom of the pipette nozzle 25 and face the n suction head outlet through holes, i.e. the space vacated by the pipette piston cylinder. The motor control button 36 is pressed, and the second motor 34 drives the screw rod 33 to reverse, and the push rod 30 and the multichannel suction head supply and receiving device 23 connected thereto move upward. In the process, the pipette nozzle 25 is inserted into the upper end of the suction head 13 and is tightly combined under the action of the friction force around, and when the multichannel suction head supply and receiving device 23 moves upward to the initial position, the multichannel pipette has installed the suction head and can start the pipetting operation.

[0026] Observe the volume display window 5, rotate the volume adjustment button 4 to the desired number, and insert the tip of the suction head 13 below the liquid level to be taken. Press the control button 3, the drive rod connected to the piston push plate drives the entire row of piston rods to move downward, release after the air is exhausted, and the liquid is sucked into the suction head 13. After the liquid is sucked, remove it and insert the suction head 13 into another container, and press the control button 3 to discharge the liquid.

[0027] After the pipetting is completed, the motor control button 36 is pressed again, and the multi-channel tip supply and collection device 23 moves downward until the upper end of the discarded tip 37 on the pipette nozzle 25 hits the detachment pin, and the detachment pin 17 clamps the tip and separates it from the pipette nozzle 25. The pipette piston cylinder and the pipette nozzle 25 leave the multi-channel tip supply and collection device 23 and the used discarded tip 37 is recovered in the multi-channel tip storage bin slider 22, and one cycle is completed.

[0028] The above is only a preferred embodiment of the present invention, and does not limit the present invention in other forms. Any technician familiar with the profession may use the above disclosed technical content to change or modify it into an equivalent embodiment with equivalent changes. However, any simple modification, equivalent change and modification made to the above embodiment according to the technical essence of the present invention without departing from the technical solution of the present invention still belongs to the protection scope of the technical solution of the present invention.

Claims

1. A multichannel pipette with a waste tip recovery function, characterized in that: The invention comprises a multi-channel pipette body, a multi-channel pipette tip supply and collection device with a pipette tip supply and collection function, and a supply and collection device driving mechanism. The supply and collection device driving mechanism is arranged beside the multi-channel pipette body. The multi-channel pipette tip supply and collection device is fixedly installed at the lower end of the supply and collection device driving mechanism and moves up and down under the drive of the supply and collection device driving mechanism. The multi-channel pipette tip supply and collection device comprises a supply and collection device housing, a multi-channel pipette tip storage bin slider and a storage bin driving mechanism. The multi-channel pipette tip storage bin slider is slidably installed in the supply and collection device housing and moves up and down under the drive of the storage bin driving mechanism. Sliding back and forth, n suction tip outlet through holes which pass through from top to bottom are arranged side by side on the shell of the supply and receiving device, and m×n suction tip supply channels are arranged in an array in the slider of the multi-channel suction tip storage bin, wherein suction tips are arranged in the rear (m-1)×n suction tip supply channels, and in the initial state, the n suction tip supply channels in the front row are opposite to the n suction tip outlet through holes, and the n suction tip piston cylinders at the lower part of the multi-channel pipette body pass through the corresponding suction tip outlet through holes and suction tip supply channels, and a release pin is arranged on the inner upper part of each suction tip supply channel.

2. A multichannel pipette with a waste tip recovery function according to claim 1, characterized in that: When the supply and receiving device driving mechanism drives the multi-channel tip supply and receiving device to move downward, the multi-channel pipette body moves upward relative to the multi-channel tip supply and receiving device until the pipette piston cylinder and the pipette nozzle at the lower part of the multi-channel pipette body leave the multi-channel tip supply and receiving device, at which time the storage bin driving mechanism drives the multi-channel tip storage bin slider to slide forward, so that the next row of n tip supply channels with clean tips are directly opposite to the n tip outlet through holes; then the multi-channel tip supply and receiving device moves upward, so that the n clean tips are correspondingly covered on the pipette nozzles at the lower ends of the n pipette piston cylinders; After completing the pipetting work, when the supply and collection device driving mechanism drives the multi-channel tip supply and collection device to move downward again, the multi-channel pipette body moves upward relative to the multi-channel tip supply and collection device until the upper end of the tip on the pipette nozzle hits the disengagement pin, and the tip is clamped by the disengagement pin to separate it from the pipette nozzle, and the pipette piston cylinder and the pipette nozzle leave the multi-channel tip supply and collection device and the used and discarded tips are recovered in the multi-channel tip storage bin slider; at this time, the storage bin driving mechanism drives the multi-channel tip storage bin slider to slide forward again, so that the next row of n tip supply channels with clean tips are opposite to the n tip outlet through holes; then the multi-channel tip supply and collection device is moved upward, so that the n clean tips are correspondingly covered on the pipette nozzles at the lower ends of the n pipette piston cylinders.

3. A multichannel pipette with a waste tip recovery function according to claim 1, characterized in that: The storage bin driving mechanism includes a first motor, a pulley and a belt transmission belt. The first motor is installed on the supply and storage device housing, and the output end of the first motor is connected to the pulley to drive the pulley to rotate. The belt transmission belt is wound around the pulley and connected to the multi-channel suction head storage bin slider to drive the multi-channel suction head storage bin slider to slide forward and backward through the forward and reverse rotation of the pulley.

4. A multichannel pipette with a waste tip recovery function according to claim 1, characterized in that: The storage bin driving mechanism is an electric cylinder mechanism, which is mounted on the housing of the supply and receiving device, and an output end of the electric cylinder mechanism is connected to a multi-channel suction head storage bin slider to drive the multi-channel suction head storage bin slider to slide forward and backward.

5. A multichannel pipette with a waste tip recovery function according to claim 1, characterized in that: The supply and receiving device driving mechanism is an electrically controlled driving mechanism, which includes a mounting frame, a power supply battery, a second motor, a screw rod, an electric push rod, a push rod and a motor control button. The mounting frame is fixedly connected to the side of the multi-channel pipette body, the power supply battery and the second motor are fixedly installed in the mounting frame, and the output end of the second motor is downwardly connected to the screw rod to drive the screw rod to rotate, the lower part of the screw rod cooperates with the electric push rod to drive the electric push rod to move up and down through the forward and reverse rotation of the screw rod, the lower end of the electric push rod is fixedly connected to the upper end of the push rod, and the lower end of the push rod is fixedly connected to the multi-channel suction head supply and receiving device; the power supply battery supplies power to the second motor, and the motor control button is connected to the control end of the second motor to control the start and stop and forward and reverse rotation of the second motor.

6. A multichannel pipette with a waste tip recovery function according to claim 1, characterized in that: The multi-channel pipette body mainly comprises a shell, a control button, a counter, a volume adjustment button, a volume display window, a pipette piston rod and a pipette piston cylinder.

7. A pipette with a multi-channel tip supply and collection device according to claim 1, characterized in that: The lower part of the multi-channel pipette body includes a piston mechanism housing, a driving rod, a piston push plate, n pipette piston rods and n pipette piston cylinders. The n pipette piston cylinders are installed side by side in the piston mechanism housing and pass through the piston mechanism housing downward. The lower end of the driving rod is fixedly connected to the upper part of the piston push plate. The lower part of the piston push plate is fixedly connected to the n pipette piston rods arranged side by side in the piston mechanism housing. The n pipette piston rods are respectively matched with corresponding pipette piston cylinders. The multi-channel pipette body drives the piston push plate and the n pipette piston rods thereunder to move up and down through the driving rod.

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