Mouth suction type manipulator

By designing an oral suction operator for in vitro embryo research, researchers can perform cell operations without removing the mask, solving the problems of experimental environment safety and experimental success rate, and achieving efficient and safe cell operations.

CN119776128APending Publication Date: 2025-04-08SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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Patent Information

Application Number
CN202411932418.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-26
Publication Date
2025-04-08

AI Technical Summary

Technical Problem

During in vitro embryo research, researchers need to take off their masks when performing cell operations, resulting in a decrease in the safety level control level of the experimental environment, which may lead to low cell contamination and experimental success rate, and even pose a hidden danger to the physical health of researchers.

Method used

An oral suction operator is designed, including the front end mouth suction section, the middle end connection section and the rear end suction/exit section. Through structures such as straight round tubes, oblique tubes and filters, researchers can perform cell operations without removing the mask, realizing stable filtration of airflow and safe operation of cells.

Benefits of technology

It achieves efficient completion of cell operations without affecting the safety of the experimental environment, ensuring the achievement of the experimental purpose, and protecting the physical safety of scientific researchers.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to a mouth suction type manipulator which comprises a mouth suction section at the front end, a connecting section at the middle end and a suction / outlet section at the rear end, the mouth suction section comprises a straight round pipe, an inclined pipe and a filter, one end of the straight round pipe is connected with one end of the filter, and the other end of the straight round pipe is connected with one end of the inclined pipe; the connecting section comprises a hose, one end of the hose is connected with the other end of the filter, the suction / discharge section comprises a hard connecting pipe, one end of the hard connecting pipe is connected with the other end of the hose, and the other end of the hard connecting pipe is connected with a glass needle. According to the mouth suction type manipulator provided by the invention, scientific researchers can carry out various cell operations by using the mouth suction device under the condition that a mask is not taken off, so that the high maintenance of an experimental environment, the efficient achievement of an experimental purpose and the guarantee of the body safety of the scientific researchers are realized, and finally, the safe operation of a laboratory is guaranteed.
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Description

Technical Field

[0001] The invention belongs to the technical field of in vitro embryo research experiments and relates to a mouth-suction type operator. Background Art

[0002] During the in vitro embryo research of mammals, scientific researchers and technicians need to operate on eggs or embryonic cells (hereinafter referred to as "cells"), perform routine experimental operations such as transfer between different culture media, cleaning after IVF, and transplantation in vivo. In order to prevent the cells from being contaminated, ensure a high success rate of the experiment, and the safety of the researchers themselves, the above experimental sites need to be selected in a barrier environment or an experimental environment with a higher cleanliness level, and scientific researchers are required to wear masks for experimental operations. At present, researchers perform cell operations with homemade straight-through mouth pipettes, and they must take off their masks when using them. Hold one end of the mouth pipette in your mouth, and use your mouth to blow / inhale air into the front end of the mouth pipette to control the transfer or cleaning of cells at the other end of the mouth pipette. Normally, the time for cell manipulation without a mask is at least ten minutes. Long-term accumulation may affect the safety level control level required for the experiment, which will conflict with the relevant regulations of the experimental site. If the mouth pipette-related experiments are performed in large quantities and for a long time, the entire laboratory environment may not be able to maintain the safety level required for the experiment, resulting in cell contamination and low experimental success rate. In severe cases, it may also pose a hidden danger to the health of scientific researchers. Summary of the invention

[0003] The present invention proposes a mouth suction manipulator, with which scientific researchers can perform various cell operations without taking off their masks, thereby achieving a high degree of maintenance of the experimental environment, efficient achievement of the experimental objectives, and ensuring the physical safety of the scientific researchers themselves, thereby ultimately ensuring the safe operation of the laboratory.

[0004] The technical solution of the present invention to solve the above problems is:

[0005] The present invention provides a mouth-suction type operator, which is special in that:

[0006] It consists of three parts: the front end mouth suction section, the middle end connection section, and the rear end suction / exhaust section;

[0007] The mouth suction section includes a straight round tube, an oblique tube and a filter, one end of the straight round tube is connected to one end of the filter, and the other end of the straight round tube is connected to one end of the oblique tube; the connecting section includes a hose, one end of the hose is connected to the other end of the filter, and the inhalation / exhalation section includes a hard connecting tube, one end of the hard connecting tube and the other end of the hose are connected to a glass needle.

[0008] Furthermore, there is an angle of 70° to 80° between the straight circular tube and the inclined tube.

[0009] Furthermore, the inclined tube is an oblate tube, the thickness of which gradually decreases from the end to the root.

[0010] Furthermore, the connection between the inclined tube and the straight circular tube is rounded.

[0011] Furthermore, the filter is used to filter water vapor in the air flow, and includes an upper cover and a lower cover. A cavity is formed inside the upper cover and the lower cover. A breathable filter material is provided in the cavity. The breathable filter material includes a spunbond non-woven fabric layer and a meltblown non-woven fabric layer. The spunbond non-woven fabric is close to the upper cover. The spunbond non-woven fabric has a waterproof function, and the meltblown non-woven fabric is made of polypropylene material with high melt index fiber. It is an ultra-fine electrostatic fiber cloth that can effectively use static electricity to absorb virus dust and droplets.

[0012] Furthermore, a rubber stopper is inserted into the outlet of the hard connecting tube, an insertion hole is provided at the center of the rubber stopper, and a glass needle is inserted into the insertion hole.

[0013] Furthermore, the upper cover and the lower cover are connected by threads.

[0014] Furthermore, the upper cover and the lower cover of the filter are provided with connecting pipes, the connecting pipe of the upper cover is connected to the straight round pipe, and the connecting pipe of the lower cover is connected to the hose.

[0015] Furthermore, a connecting end is provided at one end of the straight round tube connected to the filter, and the outer diameter of the connecting end is smaller than the outer diameter of the straight round tube.

[0016] Furthermore, the connecting pipes of the upper cover and the lower cover are respectively plug-connected with the straight round pipe and the hose.

[0017] Advantages of the present invention:

[0018] The mouth-suction manipulator provided by the present invention has a simple overall structure. Researchers can use the mouth-suction manipulator to perform various cell operations without taking off their masks, thereby achieving a high degree of maintenance of the experimental environment, efficiently achieving the experimental objectives, and ensuring the physical safety of the researchers themselves. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a structural diagram of the mouth suction operator;

[0020] Figure 2 yes Figure 1 Enlarged view of point A in the middle.

[0021] In the figure, 1. straight round tube; 2. filter; 3. hose; 4. hard connecting tube; 5. rubber stopper; 6. glass needle; 7. oblique tube; 8. upper cover; 9. lower cover; 10. breathable filter material. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention.

[0023] See also Figure 1 , a mouth-suction type operator, consists of three parts: a mouth-suction section at the front end, a connecting section at the middle end, and a suction / outlet section at the rear end.

[0024] The mouth suction section includes a straight round tube 1, an oblique tube 7 and a filter 2, one end of the straight round tube 1 is connected to one end of the filter 2, the other end of the straight round tube 1 is connected to one end of the oblique tube 7, and there is an angle of less than 90° between the straight round tube 1 and the oblique tube 7. The connecting section includes a hose 3, which is a rubber hose. One end of the hose 3 is connected to the other end of the filter 2, and the suction / exhaust section includes a hard connecting tube 4, one end of the hard connecting tube 4 is connected to the other end of the hose 3, and the other end is connected to a rubber stopper 5, the center of the rubber stopper 5 is provided with an insertion hole, and a glass needle 6 is inserted into the insertion hole.

[0025] During the in vitro embryo research of mammals, scientific and technical personnel need to transfer eggs or embryonic cells between different culture media, clean them after IVF, transplant them in vivo, and other routine experimental operations. In the specific cell operation experiment, there is no need to take off the mask when using it. The three parts of the mouth suction section at the front end, the connecting section at the middle end, and the suction / exhaust section at the rear end are connected, and the mouth suction device is inserted from the bottom edge of the mask and hung in the mouth. The scientific and technical personnel hold one end of the inclined tube 7 in the mouth and use the mouth to blow / inhale air into the mouth suction tube. The airflow passes through the inclined tube 7, the straight round tube 1, the filter 2, the hose 3, the hard connecting tube 4 and the glass needle 6 in sequence to control the entry and exit, transfer, cleaning or transplantation of cells at the other end of the mouth suction tube. Usually, in a complete cell experimental operation process, water vapor in the airflow enters the filter 2, and the filter 2 filters the water vapor. This prevents saliva and water vapor from clogging the mouth straw, and the airflow is stable during the experimental operation. Researchers can use the mouth suction manipulator to perform various cell operations without removing the mask, thereby achieving a high level of maintenance of the experimental environment, efficiently achieving the experimental objectives, and ensuring the physical safety of the researchers themselves.

[0026] As a preferred embodiment of the present invention, see Figure 1 There is an angle of 70° to 80° between the straight round tube and the oblique tube, so that the oblique tube can be hung in the mouth. Furthermore, the connection between the oblique tube and the straight round tube is rounded, and the turning point can better achieve airflow stability, and it is not easy to fall off during breathing.

[0027] As a preferred embodiment of the present invention, see Figure 1 The oblique tube 7 is an oblate tube, which is placed in the operator's mouth to increase comfort. Its thickness gradually decreases from the end to the root, so there is no need to worry about the oblique tube 7 slipping out of the mouth, and the operator can use both hands to perform other operations.

[0028] As a preferred embodiment of the present invention, see Figure 2 The filter 2 is used to filter water vapor in the airflow, and includes an upper cover 8 and a lower cover 9, which are connected by threads, and a cavity is formed inside the upper cover 8 and the lower cover 9, and a breathable filter material 10 is arranged in the cavity, and the breathable filter material 10 includes a spunbond non-woven fabric layer and a melt-blown non-woven fabric layer. The spunbond non-woven fabric is close to the upper cover, and the spunbond non-woven fabric has a water-blocking function, while the melt-blown non-woven fabric is made of a polypropylene material with a high melt index fiber, and is an ultra-fine electrostatic fiber cloth that can effectively use static electricity to absorb virus dust and droplets.

[0029] As a preferred embodiment of the present invention, see Figure 1 The upper cover 8 and the lower cover 9 of the filter 2 are provided with connecting pipes, and the connecting pipes of the upper cover 9 and the lower cover 10 are respectively plug-connected with the straight round pipe 1 and the hose 3.

[0030] As a preferred embodiment of the present invention, the straight round tube 1 is provided with a connecting end at one end connected to the filter 2, and the outer diameter of the connecting end is smaller than the outer diameter of the straight round tube 1, so that the hose 3 can be sleeved on the connecting end. The hose 3 is about 15-20cm long, 7mm in diameter, and 5mm in inner diameter, which can ensure stable airflow.

[0031] The straight round tube 1 and the oblique tube 7 are made of PPSU material, which can withstand high temperature sterilization and can be reused. There is a small hole in the middle of the rubber stopper 5, which can stably support the glass needle when inserted into it to achieve sealing. The glass capillary is a conventional consumable product. The glass needle can be drawn under an alcohol lamp, and the inner diameter of the tip can be enough to absorb mouse or rat embryonic cells.

[0032] The above descriptions are merely embodiments of the present invention and are not intended to limit the protection scope of the present invention. Any equivalent structure or equivalent process transformation made using the contents of the present invention specification and drawings, or directly or indirectly applied in other related system fields, are also included in the protection scope of the present invention.

Claims

1. A mouth-suction operator, characterized in that: It consists of three parts: the front end mouth suction section, the middle end connection section, and the rear end suction / exhaust section; The mouth-suction section comprises a straight round tube (1), an oblique tube (7) and a filter (2); one end of the straight round tube (1) is connected to one end of the filter (2); the other end of the straight round tube (1) is connected to one end of the oblique tube (7); and an angle less than 90° exists between the straight round tube (1) and the oblique tube (7); The connecting section comprises a hose (3), one end of which is connected to the other end of the filter (2). The inhalation / exhalation section comprises a hard connecting tube (4), one end of which is connected to the other end of the soft tube (3), and the other end of which is connected to a glass needle (6).

2. The mouth-suction operator according to claim 1, characterized in that: There is an angle of 70° to 80° between the straight circular tube (1) and the inclined tube (7).

3. A mouth-suction operator according to claim 2, characterized in that: The inclined tube (7) is an oblate tube, the thickness of which gradually decreases from the end to the root.

4. The mouth-suction manipulator according to claim 3, characterized in that: The connection between the inclined tube (7) and the straight circular tube (1) is rounded.

5. The mouth-suction operator according to claim 4, characterized in that: A rubber stopper (5) is inserted into the outlet of the hard connecting tube (4), an insertion hole is provided at the center of the rubber stopper (5), and a glass needle (6) is inserted into the insertion hole.

6. A mouth-suction operator according to any one of claims 1 to 5, characterized in that: The filter (2) is used to filter water vapor in an air flow, and comprises an upper cover (9) and a lower cover (10). A cavity is formed inside the upper cover (9) and the lower cover (10), and an air-permeable filter material (11) is arranged in the cavity. The air-permeable filter material (11) comprises a spunbond non-woven fabric layer and a melt-blown non-woven fabric layer.

7. The mouth-suction manipulator according to claim 6, characterized in that: The upper cover (9) and the lower cover (10) are connected via threads.

8. The mouth-suction manipulator according to claim 7, characterized in that: The upper cover (9) and the lower cover (10) of the filter (2) are provided with connecting pipes, the connecting pipe of the upper cover (9) is connected to the straight round pipe (1), and the connecting pipe of the lower cover (10) is connected to the hose (3).

9. The mouth-suction manipulator according to claim 8, characterized in that: The straight round tube (1) is provided with a connecting end at one end connected to the filter (2), and the outer diameter of the connecting end is smaller than the outer diameter of the straight round tube (1).

10. The mouth-suction manipulator according to claim 9, characterized in that: The connecting pipes of the upper cover (9) and the lower cover (10) are respectively connected to the straight round pipe (1) and the hose (3) in an inserting manner.