Microemulsion containing cyantraniliprole and lufenuron as well as preparation method and application of microemulsion

Abstract

The invention relates to the field of cowpea pod borer prevention and control pesticides, in particular to a microemulsion containing cyantraniliprole and lufenuron as well as a preparation method and application of the microemulsion. The invention discloses a microemulsion containing cyantraniliprole and lufenuron. The microemulsion is prepared from the following components in parts by weight: 6 parts of cyantraniliprole, 2-15 parts of lufenuron, 2-7 parts of a surfactant, 5 parts of dodecyl benzene sulfonate, 35-55 parts of an organic solvent and 30 parts of water, the surfactant is prepared from at least one of lauryl imidazoline betaine, an undecyl imidazoline ampholytic surfactant, lauryl sodium sulfate and tween-80; the organic solvent comprises at least one of methanol, acetone, ethyl acetate, dichloromethane and toluene. According to the application, cyantraniliprole and lufenuron are matched, and different insecticidal principles are adopted, so that the dependency of pests on a single pesticide is reduced, and the generation of drug resistance of the cowpea pod borer is slowed down.

Description

Technical Field

[0001] The present application relates to the field of pesticides for controlling cowpea pod borers, and specifically to a microemulsion containing cyantraniliprole and lufenuron, and a preparation method and application thereof. Background Art

[0002] Adult cowpea pod borers mostly emerge at night, rest in shaded places such as the back of leaves at the bottom of crops during the day, and start to move at night, with the most activity at 10-11 pm. They are weakly phototactic. Cowpea pod borers like warmth and humidity, and have a wide range of adaptability to environmental temperatures. High temperature and high humidity are conducive to the occurrence and development of cowpea pod borers. In summer, from July to August, cowpea pod borers can complete one generation in 24-30 days. Cowpea pod borers feed on the flower buds, pods and leaves of host legume vegetables as larvae, often causing flowers, buds and tender pods to fall off. Pods damaged by cowpea pod borers have insect feces accumulated inside and outside the holes. The damaged pods taste bitter and are not only inedible, but also easily affected by other environmental factors and become moldy, seriously affecting the quality and yield of legume vegetables.

[0003] Cyantraniliprole, also known as cyantraniliprole, is a second-generation nicotinic acid receptor inhibitor insecticide. This type of insecticide activates the nicotinic acid receptors of target pests, releases calcium in striated and smooth muscle cells, and causes paralysis and death of pests. It has a good control effect on lepidopteran pests and piercing-sucking pests. Lufenuron is the latest generation of urea-replacing insecticides. The agent kills pests by acting on insect larvae and preventing the molting process. It has the effects of stomach poison and contact killing, multiple egg killing, and high-efficiency insecticide.

[0004] Both cyantraniliprole and lufenuron have good control effects on cowpea pod borers, but the solubility of cyantraniliprole and lufenuron in organic solvents is inconsistent, and it is difficult to dissolve in water. Most of cyantraniliprole and lufenuron are formulated separately into corresponding pesticides. Therefore, in daily production, in order to prevent pests from developing resistance, farmers mostly spray cyantraniliprole and lufenuron separately for prevention and control. Although it is effective in preventing pests from developing resistance, in actual operations, the concentration of cyantraniliprole or lufenuron is often continuously increased until it is found that the pest control effect is not good, and then consider using another pesticide. This way of use not only increases production costs, but also has more impacts on the environment. Summary of the invention

[0005] In order to solve the problem that cyantraniliprole and lufenuron are difficult to compound, the present application provides a microemulsion containing cyantraniliprole and lufenuron, which improves the solubility of cyantraniliprole and lufenuron in water through the combination of specific surfactants and organic solvents, completes the compounding of cyantraniliprole and lufenuron, and thus improves the control effect of the microemulsion containing cyantraniliprole and lufenuron on cowpea pod borer.

[0006] In a first aspect, the present application provides a microemulsion containing cyantraniliprole and lufenuron, using the following technical scheme: a microemulsion containing cyantraniliprole and lufenuron, comprising the following components in parts by weight: 6 parts of cyantraniliprole, 2-15 parts of lufenuron, 2-7 parts of a surfactant, 5 parts of dodecylbenzene sulfonate, 35-55 parts of an organic solvent, and 30 parts of water; The surfactant comprises at least one of lauryl imidazoline betaine, undecyl imidazoline amphoteric surfactant, sodium lauryl sulfate and Tween-80; The organic solvent includes at least one of methanol, acetone, ethyl acetate, dichloromethane and toluene.

[0007] By adopting the above technical solution, cyantraniliprole and lufenuron have different mechanisms of action, so when mixed, they can play their respective advantages and prevent pests from developing resistance due to long-term use of a single pesticide. Cyantraniliprole is a nicotinic acid receptor modulator, which activates the nicotinic acid receptors in insect muscles, causing insect muscle contraction, paralysis and eventual death. Lufenuron inhibits the activity of insect chitin synthase, hinders the synthesis of chitin in the pest epidermis, and causes the pest to die due to the inability to molt normally.

[0008] The surfactant in the microemulsion can reduce the surface tension of water, making it easier for the microemulsion to spread and penetrate on the plant surface, thereby improving the utilization rate and control effect of the pesticide. The organic solvent can dissolve pesticide ingredients such as cyantraniliprole and lufenuron to form a uniform microemulsion. These solvents are also volatile and can evaporate quickly after use, reducing pesticide residues.

[0009] The present application uses cyantraniliprole to cause insect muscle contraction, paralysis and eventual death, and lufenuron to cause the insect to die due to the inability to molt normally. Through the combination of cyantraniliprole and lufenuron, different insecticidal principles are adopted to reduce the dependence of pests on a single pesticide and slow down the development of resistance of cowpea pod borer.

[0010] Preferably, the mass ratio of cyantraniliprole to lufenuron is 6:3-9.

[0011] By adopting the above technical solution, the selection of the above ratio range is based on the consideration of synergistic effect. When the mass ratio of cyantraniliprole and lufenuron is within this range, they can produce a better synergistic effect. This means that the two can cooperate with each other in chemical properties and biological activities to improve the overall insecticidal effect. If the amount of lufenuron is too much or too little, this synergistic effect may be destroyed, resulting in a decrease in the overall effect.

[0012] Preferably, the weight portion of the lauryl imidazoline betaine is 2-5 parts.

[0013] By adopting the above technical solution, lauryl imidazoline betaine is an excellent amphoteric surfactant, which contains anionic and cationic ionic groups in its molecular structure, and therefore has unique physical and chemical properties. This surfactant has high solubility in water, is stable to hard water, and is not easily affected by water quality and becomes ineffective.

[0014] The solubility of cyantraniliprole and lufenuron in water is low, which limits their application in pesticide formulations. As an amphoteric surfactant, the positive and negative charge centers in the molecule of lauryl imidazoline betaine can produce stronger interactions with cyantraniliprole and lufenuron molecules to form a stable complex. This interaction helps to break the interaction between cyantraniliprole and lufenuron molecules, making them easier to disperse in water, thereby improving their solubility.

[0015] Compared with conventional surfactants such as sodium dodecyl sulfate and Tween-80, lauryl imidazoline betaine can produce stronger interactions with cyantraniliprole and lufenuron molecules due to its unique amphoteric structure, forming a more stable complex. Lauryl imidazoline betaine has good biodegradability and low toxicity, is environmentally friendly and safe for the human body.

[0016] Preferably, the weight portion of the undecyl imidazoline amphoteric surfactant is 2-5 parts.

[0017] By adopting the above technical solution, the undecyl imidazoline amphoteric surfactant and the lauryl imidazoline betaine are both amphoteric surfactants, which can produce stronger interactions with cyantraniliprole and lufenuron molecules to form a stable complex, making cyantraniliprole and lufenuron easier to disperse in water, thereby improving their solubility.

[0018] Compared with conventional surfactants such as sodium dodecyl sulfate and Tween-80, undecyl imidazoline amphoteric surfactants can produce stronger interactions with cyantraniliprole and lufenuron molecules to form more stable complexes.

[0019] Preferably, the weight portion of the methanol is 35-50 parts.

[0020] By adopting the above technical solution, since cyantraniliprole and lufenuron are more soluble in methanol, using methanol as a solvent can more effectively dissolve these two pesticide components when preparing pesticide formulations. This can not only reduce the amount of solvent used, but also improve the concentration and uniformity of the pesticide formulation, thereby ensuring that the pesticide can fully exert its efficacy when used.

[0021] Since methanol has a strong solubility, a relatively small amount of methanol is required to achieve the same dissolution effect. This can not only reduce production costs, but also reduce the impact on the environment. At the same time, less solvent usage also means less handling and storage costs.

[0022] Preferably, the weight portion of acetone is 35-45 parts.

[0023] By adopting the above technical solution, acetone, as a polar solvent, has excellent solubility for cyantraniliprole and lufenuron. This means that when preparing pesticide formulations, acetone can dissolve these two active ingredients more effectively, ensuring high concentration and uniformity of the formulations. This efficient solubility performance not only helps to improve the insecticidal effect of pesticides, but also reduces the overall use of solvents, thereby reducing costs. Due to the strong solubility of acetone for cyantraniliprole and lufenuron, the demand for acetone is significantly reduced compared to other solvents. This reduces production costs, while reducing energy consumption and emissions during handling, storage and transportation, and is more environmentally friendly.

[0024] Acetone has good compatibility with other formulation ingredients (such as surfactants, water, etc.), which helps to form stable microemulsions or suspensions. This stability is crucial to the performance of pesticide formulations during storage and use, ensuring that the pesticide can maintain its insecticidal activity after long-term storage.

[0025] Preferably, the organic solvent is a mixture of methanol and acetone, and the mass ratio of methanol to acetone is 1:1.5-2.5.

[0026] By adopting the above technical solution, the mixture of methanol and acetone can produce a synergistic effect at a specific ratio, which means that the interaction between them can improve the overall solubility. Acetone is used as a true solvent and methanol is used as a co-solvent, which enables the solvent system to better interact with pesticide ingredients such as cyantraniliprole and lufenuron, thereby improving the solubility efficiency. The mixture shows a strong solubility that exceeds that of acetone alone.

[0027] In a second aspect, the present application provides a method for preparing a microemulsion containing cyantraniliprole and lufenuron, using the following technical solution: A method for preparing a microemulsion containing cyantraniliprole and lufenuron, which is used for preparing the microemulsion containing cyantraniliprole and lufenuron, comprises the following steps: uniformly mixing formulated amounts of cyantraniliprole, lufenuron, a surfactant, dodecylbenzenesulfonate, an organic solvent and water to obtain the microemulsion containing cyantraniliprole and lufenuron.

[0028] By adopting the above technical solution, cyantraniliprole and lufenuron have good solubility in organic solvents, which helps them to be evenly distributed in the microemulsion. In practical application, the surfactant can help cyantraniliprole and lufenuron to disperse in water, which is convenient for spraying and is conducive to crop absorption, thereby achieving pest control.

[0029] In a third aspect, the present application provides an application of a microemulsion containing cyantraniliprole and lufenuron, using the following technical solution: A microemulsion containing cyantraniliprole and lufenuron is used in the prevention and control of cowpea pod borer.

[0030] By adopting the above technical solution, cyantraniliprole and lufenuron can work synergistically and exert insecticidal effects together. They are highly toxic to the larvae of cowpea pod borer, can quickly kill pests, and effectively control the population of pests. The microemulsion has a long lasting effect and can maintain the control effect on cowpea pod borer for a long time. This helps to reduce the number and amount of pesticides used and reduce production costs.

[0031] Preferably, the microemulsion containing cyantraniliprole and lufenuron is diluted with 40 kg of water per mu of cowpea, and the dosage of the microemulsion containing cyantraniliprole and lufenuron is 4-6 mL.

[0032] By adopting the above technical solution, 40 kilograms (kg) of water are used for dilution per mu. This means that in order to prepare the required pesticide solution per mu, 4-6 mL of microemulsion containing cyantraniliprole and lufenuron needs to be evenly dissolved or dispersed in 40 kg of water. If the dosage of the microemulsion is too low, it may cause uneven distribution on the cowpea plants and fail to fully cover the habitat and activity area of ​​the pests. Insufficient dosage may also cause the concentration of active ingredients in the microemulsion to be too low, and it may not produce sufficient toxic effects on pests, thereby affecting the control effect. Excessive use of microemulsions will increase the amount and cost of pesticides used and reduce the economic benefits of agricultural production. In addition, excessive use of microemulsions may also cause pesticide damage.

[0033] In summary, this application has the following beneficial effects: 1. Since cyantraniliprole is used in this application to cause insect muscle contraction, paralysis and eventual death, lufenuron causes the insect to be unable to molt normally and die. By combining cyantraniliprole and lufenuron, different insecticidal principles are adopted to reduce the dependence of insects on a single pesticide and slow down the development of insecticide resistance in cowpea pod borer; 2. Compared with conventional surfactants such as sodium dodecyl sulfate and Tween-80, the lauryl imidazoline betaine and undecyl imidazoline amphoteric surfactants in the present application can produce stronger interactions with cyantraniliprole and lufenuron molecules due to their unique amphoteric structures, forming more stable complexes; 3. The present application achieves a synergistic effect by using a mixture of methanol and acetone at a specific ratio, so that the solvent system can better interact with pesticide ingredients such as cyantraniliprole and lufenuron, thereby improving the dissolution efficiency. DETAILED DESCRIPTION

[0034] The raw materials in this application include the following parts: Cyantraniliprole: a commercially available product with CAS number 736994-63-1; Lufenuron: a commercial product with CAS No. 736994-63-1 was used; Lauryl imidazoline betaine: a commercial product with CAS number 504-75-6; Undecyl imidazoline amphoteric surfactant: a commercially available product with CAS number 29249-55-6; Sodium lauryl sulfate: a commercially available product with CAS number 151-21-3; Tween-80: a commercially available product with CAS No. 9005-65-6 was used; Dodecylbenzene sulfonate: including calcium dodecylbenzene sulfonate, sodium dodecylbenzene sulfonate, triethanolamine dodecylbenzene sulfonate, etc. This application uses the commercially available calcium dodecylbenzene sulfonate product with CAS No. 26264-06-2 as an example; Methanol: a commercial product with CAS number 67-56-1 was used; Acetone: a commercially available product with CAS number 67-64-1; Ethyl acetate: a commercially available product with CAS number 141-78-6 is used; Dichloromethane: a commercially available product with CAS number 75-09-2; Toluene: a commercial product with CAS number 108-88-3; Water: a commercial product with CAS number 7732-18-5 was used; The present application is further described in detail below with reference to examples and comparative examples.

[0035] Example 1 A method for preparing a microemulsion containing cyantraniliprole and lufenuron comprises the following steps: 6 g of cyantraniliprole, 6 g of lufenuron, 5 g of lauryl imidazoline betaine, 5 g of calcium dodecylbenzenesulfonate, 50 g of methanol and 30 g of water were uniformly mixed to obtain a microemulsion containing cyantraniliprole and lufenuron.

[0036] Embodiment 2-6 In Example 2-6, based on the preparation method of Example 1, the contents of cyantraniliprole and lufenuron were adjusted, and the specific adjustments are shown in Table 1.

[0037] Comparative Example 1 Comparative Example 1 Based on the preparation method of Example 1, the contents of cyantraniliprole and lufenuron were adjusted, and the specific adjustments are shown in Table 1.

[0038] Table 1 Contents and performance test table of cyantraniliprole and lufenuron in Examples 1-6 and Comparative Example 1 The microemulsions containing cyantraniliprole and lufenuron of Examples 1-5 and Comparative Example 1 were subjected to the following performance tests. The test results are shown in Table 1.

[0039] Indoor toxicity test of cowpea pod borer Using the NY / T1154.7-2006 Pesticide Indoor Bioassay Test Guidelines, Part 7, the LC values ​​of cyantraniliprole, lufenuron and each microemulsion were calculated. 50 Value and LC 90 The DPS statistical software was used to perform regression analysis on the logarithmic values ​​of the treatment concentrations of each single agent and different mixed combinations and the corresponding inhibition rate probability values, and the toxicity regression curve and correlation coefficient were calculated. The co-toxicity coefficient of the mixture was calculated according to the Sun Yunpei method. The co-toxicity coefficient (CTC) of the compound combination ≥ 120 showed a synergistic effect; CTC ≤ 80 showed an antagonistic effect; 80 < CTC < 120 showed an additive effect. In this experiment, cowpea pod borer was used, and the concentrations of the microemulsions were 500, 100, 50, 10, 5, 1, 0.5, and 0.1 mg / L, respectively.

[0040] Referring to Table 1, by comparing Examples 1-5 with Comparative Example 1, the LC values ​​of the microemulsions of Examples 1-5 for pod borer are 50 Values, LC values ​​of cyantraniliprole and lufenuron alone for pod borer 50 Values ​​between; LC of Examples 1, 3 and 5 90 The value is lower than the LC of cyantraniliprole and lufenuron alone for pod borer 90 Value, LC of Examples 2, 4, and 6 90 LC values ​​of cyantraniliprole and lufenuron for pod borer 90 Values ​​between; LC of pod borer of microemulsion of comparative example 1 50 Value and LC 90 The values ​​were between the LC values ​​of cyantraniliprole and lufenuron for pod borer 50 Value and LC 90 values, especially the LC of microemulsion for pod borer 90 The value reached the LC value of lufenuron alone for pod borer 90The value was about 63%, and the co-toxicity coefficient of C. pod borer showed an additive effect of 100.10. This shows that the combination of cyantraniliprole and lufenuron has a good control effect on cowpea pod borer, and the mass ratio of cyantraniliprole to lufenuron in the combination is 1:1, 2:1, 7:3 and 2:3, which shows a synergistic effect and is more conducive to improving the control effect.

[0041] In addition, by comparing Examples 1-6, it was found that the co-toxicity coefficient of Example 1 was the highest, and the LC of the pod borer of Example 1 was 90 Therefore, taking all factors into consideration, Example 1 is preferred.

[0042] Embodiment 6-8 In Example 6-8, based on the preparation method of Example 1, the amount of lauryl imidazoline betaine added was adjusted. The specific adjustment is shown in Table 2.

[0043] Comparative Example 2 Comparative Example 2 is based on the preparation method of Example 1, except that lauryl imidazoline betaine is not added, and other conditions remain unchanged.

[0044] The microemulsions containing cyantraniliprole and lufenuron of Examples 6-8 and Comparative Example 2 were subjected to the following performance tests. The test results are shown in Table 2.

[0045] Table 2 Addition amount and performance test table of lauryl imidazoline betaine in Example 1, Examples 6-8 and Comparative Example 2 project Example 1 Example 6 Example 7 Example 8 Comparative Example 2 Lauryl imidazoline betaine / g 5 2 4 7 0 Dispersibility / % 96.3 91.7 94.6 96.3 75.3 Performance Testing Dispersibility The dispersibility (%) of the microemulsions containing cyantraniliprole and lufenuron of Examples 1 and Examples 6-8 after being dissolved in water was determined according to GB / T 32775-2016 on pesticide dispersibility.

[0046] Referring to Table 2, by comparing Example 1, Examples 6-8 and Comparative Example 2, it can be seen that the dispersibility of Examples 1 and Examples 6-7 is much higher than that of Comparative Example 2, indicating that the addition of lauryl imidazoline betaine can effectively improve the dispersibility of the microemulsion containing cyantraniliprole and lufenuron in water.

[0047] As the amount of lauryl imidazoline betaine added gradually increased, the dispersibility of the microemulsion containing cyantraniliprole and lufenuron became greater and greater, probably because lauryl imidazoline betaine, as an amphoteric surfactant, the positive and negative charge centers in its molecules can produce stronger interactions with cyantraniliprole and lufenuron molecules to form a stable complex. This interaction helps to break the interaction between cyantraniliprole and lufenuron molecules, making them easier to disperse in water, thereby improving their solubility.

[0048] Examples 9-12 Example 9 Based on the preparation method of Example 1, 5 g of lauryl imidazoline betaine was replaced with 5 g of undecyl imidazoline amphoteric surfactant, and the other conditions remained unchanged.

[0049] In Examples 10-12, based on the preparation method of Example 9, the amount of undecyl imidazoline amphoteric surfactant added was adjusted. The specific adjustments are shown in Table 3.

[0050] The microemulsions containing cyantraniliprole and lufenuron of Examples 9-12 were subjected to the following performance tests. The test results are shown in Table 3.

[0051] Table 3 Addition amount and performance test table of undecyl imidazoline amphoteric surfactant in Example 1 and Example 9-12 Referring to Table 3, it can be seen from the comparison between Example 1 and Examples 9-12 that as the amount of undecyl imidazoline amphoteric surfactant added gradually increases, the dispersibility of the microemulsion containing cyantraniliprole and lufenuron becomes greater and greater, which may be because the undecyl imidazoline amphoteric surfactant is an amphoteric surfactant, and the positive and negative charge centers in its molecules can produce stronger interactions with cyantraniliprole and lufenuron molecules to form a stable complex. This interaction helps to break the interaction force between cyantraniliprole and lufenuron molecules, making them easier to disperse in water, thereby improving their solubility.

[0052] Examples 13-16 Example 13 Based on the preparation method of Example 1, the type and addition amount of the surfactant are adjusted. The specific adjustments are shown in Table 4.

[0053] The microemulsions containing cyantraniliprole and lufenuron of Examples 13-16 were subjected to the following performance tests. The test results are shown in Table 4.

[0054] Table 4: Types and addition amounts of surfactants and performance test tables for Examples 1 and 13-16 Referring to Table 4, it can be seen from the comparison between Example 1 and Examples 13-16 that, compared with conventional surfactants such as sodium dodecyl sulfate and Tween-80, lauryl imidazoline betaine can produce stronger interactions with cyantraniliprole and lufenuron molecules due to its unique amphoteric structure, forming a more stable complex. This interaction helps to break the interaction between cyantraniliprole and lufenuron molecules, making them easier to disperse in water, thereby improving their dispersibility.

[0055] Examples 17-19 In Examples 17-19, based on the preparation method of Example 1, the amount of methanol added was adjusted, as shown in Table 5 for details.

[0056] Comparative Example 3 Comparative Example 3 Based on the preparation method of Example 1, the amount of methanol added was adjusted, as shown in Table 5.

[0057] The microemulsions containing cyantraniliprole and lufenuron of Examples 17-19 and Comparative Example 3 were subjected to the following performance tests. The test results are shown in Table 5.

[0058] Table 5: Amount of methanol added and performance test table of Example 1, Examples 17-19 and Comparative Example 3 Referring to Table 5, it can be seen from the comparison of Example 1, Examples 17-19 and Comparative Example 3 that as the amount of methanol added gradually increases, the dispersibility of the microemulsion containing cyantraniliprole and lufenuron becomes greater and greater. This may be because cyantraniliprole and lufenuron gradually dissolve in methanol, which increases the solubility of the microemulsion containing cyantraniliprole and lufenuron in water, thereby improving the dispersibility.

[0059] Examples 20-23 Example 20 Based on the preparation method of Example 1, 50g of methanol is replaced with 45g of acetone, and other conditions remain unchanged.

[0060] In Examples 21-23, based on the preparation method of Example 20, the amount of acetone added was adjusted, as shown in Table 6 for details.

[0061] The microemulsions containing cyantraniliprole and lufenuron of Examples 20-23 were subjected to the following performance tests. The test results are shown in Table 6.

[0062] Table 6 Amount of acetone added and performance test table of Example 1 and Examples 20-23 Referring to Table 6, it can be seen from the comparison between Example 1 and Examples 20-23 that as the amount of acetone added gradually increases, the dispersibility of the microemulsion containing cyantraniliprole and lufenuron becomes greater and greater, which may be because cyantraniliprole and lufenuron gradually dissolve in acetone, thereby increasing the solubility of the microemulsion containing cyantraniliprole and lufenuron in water, thereby increasing the dispersibility. Among them, the solubility of cyantraniliprole and lufenuron in acetone is higher than that in methanol, so after the organic solvent is replaced by acetone from methanol, the solubility of the microemulsion containing cyantraniliprole and lufenuron in water is higher.

[0063] Examples 24-28 Example 24 Based on the preparation method of Example 20, 45g of acetone is adjusted to 45g of a mixture of methanol and acetone, the mass ratio of methanol to acetone in the mixture is 1:2, and other conditions remain unchanged.

[0064] In Examples 25-28, based on the preparation method of Example 24, the mass ratio of methanol to acetone was adjusted, as shown in Table 7 for details.

[0065] The microemulsions containing cyantraniliprole and lufenuron of Examples 24-28 were subjected to the following performance tests. The test results are shown in Table 7.

[0066] Table 7 Mass ratio of methanol to acetone and performance test table of Example 1, Example 20 and Examples 24-28 Referring to Table 7, it can be seen from the comparison of Example 1, Example 20 and Examples 24-28 that the mixture of methanol and acetone can produce a synergistic effect at a specific ratio, which means that the interaction between them can improve the overall solubility. When the mass ratio of methanol to acetone is 1:1.5-2.5, acetone is used as a true solvent and methanol is used as a co-solvent, so that the solvent system can better interact with pesticide components such as cyantraniliprole and lufenuron, thereby improving the dissolution efficiency. The mixture exhibits a strong solubility that exceeds that of acetone alone.

[0067] Examples 29-31 Example 29 Based on the preparation method of Example 1, 50g of methanol is replaced with 55g of ethyl acetate, and other conditions remain unchanged.

[0068] Example 30 Based on the preparation method of Example 1, 50g of methanol is replaced with 55g of dichloromethane, and other conditions remain unchanged.

[0069] Example 31 Based on the preparation method of Example 1, 50g of methanol is replaced with 55g of toluene, and other conditions remain unchanged.

[0070] The microemulsions containing cyantraniliprole and lufenuron of Examples 29-31 were subjected to the following performance tests. The test results are shown in Table 8.

[0071] Table 8 Types and addition amounts of organic solvents and performance test table of Example 1, Example 20 and Examples 29-31 project Example 1 Embodiment 20 Embodiment 29 Embodiment 30 Embodiment 31 Types of organic solvents Methanol acetone Ethyl acetate Dichloromethane Toluene Addition amount / g 50 45 55 55 55 Dispersibility / % 96.3 97.4 95.3 93.6 94.8 Referring to Table 8, it can be seen from the comparison of Example 1, Example 20 and Examples 29-31 that ethyl acetate, dichloromethane and toluene can all be used in the present application, but the solubility of cyantraniliprole in ethyl acetate, dichloromethane and toluene is lower than that in methanol and acetone, so the dispersibility of the microemulsion is also low.

[0072] Application Examples The above-mentioned embodiments 1-31 can all be put into practical application, and the following application examples are illustrated with the basic formula of embodiment 1.

[0073] Preparation Example 1-3 Preparation Example 1 is to dilute 4 mL of the microemulsion containing cyantraniliprole and lufenuron of Example 1 in 40 liters of water per acre of crop area to obtain diluted pesticide 1.

[0074] Preparation Example 2 is to dilute 5 mL of the microemulsion containing cyantraniliprole and lufenuron of Example 1 in 40 liters of water per acre of crop area to obtain diluted pesticide 2.

[0075] In Preparation Example 3, 6 mL of the microemulsion containing cyantraniliprole and lufenuron of Example 6 was diluted in 40 liters of water per acre of crop area to obtain diluted pesticide 3.

[0076] Comparative Examples 4-6 Comparative Example 4 is to dilute 6 mL of the microemulsion of Comparative Example 2 in 40 liters of water per acre of crop area to obtain comparative diluted pesticide 1.

[0077] Comparative Example 5 is to dilute 30 mL of 100 g / L cyantraniliprole suspension in 40 liters of water per acre of crop area to obtain comparative diluted pesticide 2.

[0078] Comparative Example 6 is to dilute 30 mL of 20% lufenuron suspension in 40 liters of water per acre of crop area to obtain comparative diluted pesticide 3.

[0079] Preparation Examples 1-3 and Comparative Examples 4-6 were used for field control of the following cowpea pod borers and wheat aphids, and the results obtained are shown in Table 9.

[0080] Control of Cowpea Pod Borer The diluted pesticides were sprayed evenly on the cowpea plants, and the mortality rate of cowpea pod borers was investigated 3, 7 and 10 days after the spraying. The base number of cowpea pod borers before the spraying and the number of live insects after the spraying were investigated for each liquid treatment, and the mortality rate was calculated.

[0081] Table 9 Control effect of Preparation Examples 1-3 and Comparative Examples 4-6 on cowpea pod borer Referring to Table 9, by comparing Preparation Examples 1-3 and Comparative Examples 4-6, it can be seen that the control effects of Preparation Examples 1-3 on cowpea pod borer are better than those of Comparative Examples 4-6. The microemulsion containing cyantraniliprole and lufenuron in the present application has better water solubility, which helps to fully disperse its active ingredients.

[0082] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.

Claims

1. A microemulsion containing cyantraniliprole and lufenuron, characterized in that: The invention comprises the following components in parts by weight: 6 parts of cyantraniliprole, 2-15 parts of lufenuron, 2-7 parts of a surfactant, 5 parts of dodecylbenzene sulfonate, 35-55 parts of an organic solvent, and 30 parts of water; The surfactant comprises at least one of lauryl imidazoline betaine, undecyl imidazoline amphoteric surfactant, sodium lauryl sulfate and Tween-80; The organic solvent includes at least one of methanol, acetone, ethyl acetate, dichloromethane and toluene.

2. The microemulsion containing cyantraniliprole and lufenuron according to claim 1, characterized in that: The mass ratio of cyantraniliprole to lufenuron is 6:3-9.

3. The microemulsion containing cyantraniliprole and lufenuron according to claim 1, characterized in that: The weight portion of the lauryl imidazoline betaine is 2-5 parts.

4. The microemulsion containing cyantraniliprole and lufenuron according to claim 1, characterized in that: The weight portion of the undecyl imidazoline amphoteric surfactant is 2-5 parts.

5. The microemulsion containing cyantraniliprole and lufenuron according to claim 1, characterized in that: The weight portion of the methanol is 35-50 parts.

6. The microemulsion containing cyantraniliprole and lufenuron according to claim 1, characterized in that: The weight portion of the acetone is 35-45 parts.

7. The microemulsion containing cyantraniliprole and lufenuron according to claim 1, characterized in that: The organic solvent is a mixture of methanol and acetone, and the mass ratio of the methanol to the acetone is 1:1.5-2.

5.

8. A method for preparing a microemulsion containing cyantraniliprole and lufenuron as claimed in any one of claims 1 to 7, characterized in that: The method comprises the following steps: uniformly mixing the formulated amounts of cyantraniliprole, lufenuron, a surfactant, dodecylbenzene sulfonate, an organic solvent and water to obtain a microemulsion containing cyantraniliprole and lufenuron.

9. The use of the microemulsion containing cyantraniliprole and lufenuron according to any one of claims 1 to 7, characterized in that: Applications include control of cowpea pod borer.

10. The use of the microemulsion containing cyantraniliprole and lufenuron according to claim 9, characterized in that: The microemulsion containing cyantraniliprole and lufenuron is diluted with 40 kg of water per mu of cowpea, and the dosage of the microemulsion containing cyantraniliprole and lufenuron is 4-6 mL.

Images