Cell suspension separation and purification equipment

Abstract

The invention relates to the technical field of cell suspension separation and purification, and discloses cell suspension separation and purification equipment which comprises a separation table, the bottom end of the separation table is fixedly connected with anti-skid feet, a cover plate is hinged to the rear side of the top end of the separation table, the bottom end of the cover plate is fixedly connected with a cover turning mechanism, and a storage groove is formed in the rear side of the separation table. A mounting groove is formed in the top end of the separation table, a separation mechanism is movably connected to the interior of the mounting groove, an auxiliary mechanism is fixedly connected to the top end of the separation mechanism, and an operation screen is fixedly connected to the front side of the separation table. According to the device, a separation seat can be taken out through a handle after work is completed, so that cleaning and disinfection by personnel are facilitated, pollution of a cell suspension during next use is prevented, an extension column extends out of a storage column under the action of centrifugal force, and thus the storage column drives an auxiliary block to cover the top end of a test tube.

Description

Technical Field

[0001] The invention relates to the technical field of cell suspension separation and purification, in particular to a cell suspension separation and purification device. Background Art

[0002] Stem cells are a type of cell with unlimited or immortal self-renewal capabilities and can produce at least one type of highly differentiated daughter cells. Most biologists and medical scientists believe that stem cells are a type of cell that comes from embryos, fetuses or adults and has unlimited self-renewal, proliferation and differentiation capabilities under certain conditions. They can produce daughter cells with exactly the same phenotype and genotype as themselves, as well as specialized cells that make up the body's tissues and organs, and can also differentiate into progenitor cells.

[0003] In the prior art, for example, the application number CN219861318U discloses a stem cell purification device, which includes a housing, a centrifugal assembly and a filtration assembly; a partition is provided in the housing, and the partition separates the internal space of the housing to form a centrifugal area and a filtration area; the centrifugal assembly is installed in the centrifugal area to centrifuge stem cells; the filtration assembly is installed in the filtration area to filter stem cells; the centrifugal assembly and the filtration assembly cooperate to purify stem cells. The present application centrifuges stem cells in the centrifugal area through the centrifugal assembly.

[0004] However, the above patent is difficult to use, and the stability of the test tube during internal rotation purification cannot be effectively guaranteed, which can easily lead to the test tube falling off or being damaged. In addition, it is difficult to disassemble during use and it takes a long time. Summary of the invention

[0005] The purpose of the present invention is to provide a cell suspension separation and purification device to solve the problems in the prior art.

[0006] The purpose of the present invention can be achieved through the following technical solutions:

[0007] A cell suspension separation and purification device comprises a separation table, the bottom end of the separation table is fixedly connected with an anti-slip foot, the top rear side of the separation table is hinged with a cover plate, and the bottom end of the cover plate is fixedly connected with a flip mechanism, the rear side of the separation table is provided with a storage groove, the top of the separation table is provided with a mounting groove, and the interior of the mounting groove is movably connected with a separation mechanism, the top of the separation mechanism is fixedly connected with an auxiliary mechanism, and the front side of the separation table is fixedly connected with an operation screen.

[0008] Preferably, the separation mechanism includes a motor 1, a gear 1, a gear ring, a magnetic block, a separation seat and a handle, the output end of the motor 1 is fixedly connected to the axis of the gear, there are multiple magnetic blocks, and the magnetic blocks are all fixedly connected to the inner wall of the magnetic ring, the gear ring is meshed with the gear, and the outer wall of the separation seat is provided with multiple slots, and the slots are consistent with the magnetic blocks.

[0009] Preferably, the separation seat is rotatably connected to the inside of the installation slot, the motor is fixedly connected to the inside of the installation slot, and a connecting column is fixedly connected to the top of the separation seat.

[0010] Preferably, a separation groove is provided inside the top of the separation seat, the magnetic block is attracted to the slot, and the handle is hinged to the top of the separation seat.

[0011] Preferably, the auxiliary mechanism includes a storage column, an extension column, a spring, a folding rod, an auxiliary block and a connecting column, and the storage column is provided in plurality, one end of the storage column is fixedly connected to the outer wall of the connecting column, the extension column is movably connected to the inside of the storage column, one end of the spring is fixedly connected to the inner wall of the storage column, and the other end of the spring is fixedly connected to one end of the extension column, and the other end of the extension column is fixedly connected to one side of the auxiliary block.

[0012] Preferably, both ends of the folding rod are respectively hinged to the outer wall of the other end of the extension column, the bottom end of the connecting column is fixedly connected to the top of the separation seat, and the other side of the auxiliary block is interactively connected to the inner wall of the top of the separation seat.

[0013] Preferably, the flip cover mechanism includes motor 2, a push plate, a screw, a tooth plate and gear 2, the output end of motor 2 is fixedly connected to one end of the screw, one side of the push plate is threadedly connected to the outer wall of the screw, and the top of the other side of the push plate is fixedly connected to one end of the tooth plate, the tooth plate is provided with two left-right symmetrical ones, and the tooth plate is movably connected to the bottom of gear 2.

[0014] Preferably, the tooth plate is meshed with gear 2, the push plate is movably connected to the inside of the storage groove, the tooth plate is slidably connected to the inside of the top of the storage groove, the gear 2 is fixedly connected to one side of the bottom end of the cover plate, and the motor 2 is fixedly connected to the outer wall of the separation table.

[0015] Beneficial effects of the present invention:

[0016] 1. The present invention drives the separation seat to rotate through the gear ring, thereby separating and purifying the cell suspension. After the work is completed, the separation seat can be taken out by the handle, so that it is convenient for personnel to clean and disinfect, and prevent the cell suspension from being contaminated when it is used next time;

[0017] 2. The present invention uses centrifugal force to make the extension column protrude from the inside of the storage column, so that the storage column drives the auxiliary block to cover the top of the test tube, thereby preventing the test tube cover from falling off during the work process, affecting the use of personnel;

[0018] 3. The present invention drives the gear 2 to rotate through the toothed plate, and the gear 2 will drive the cover plate to flip upwards while rotating. This device can make it more convenient for personnel to operate, and can effectively prevent the cover plate from loosening, thereby improving efficiency during use. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The present invention will be further described below in conjunction with the accompanying drawings.

[0020] Figure 1 It is a three-dimensional structural schematic diagram of the present invention;

[0021] Figure 2 It is a schematic diagram of the explosion structure of the present invention;

[0022] Figure 3 The present invention Figure 2 A side view schematic diagram of the structure;

[0023] Figure 4 It is a schematic diagram of the explosion structure of the auxiliary mechanism of the present invention;

[0024] Figure 5 It is a structural schematic diagram of the separation mechanism and its connecting parts of the present invention;

[0025] Figure 6 The present invention Figure 5 Schematic diagram of the enlarged structure at point A in the middle.

[0026] 1. Separation table; 2. Anti-slip feet; 3. Cover plate; 4. Flip mechanism; 401. Motor 2; 402. Push plate; 403. Screw; 404. Tooth plate; 405. Gear 2; 5. Storage slot; 6. Installation slot; 7. Separation mechanism; 701. Motor 1; 702. Gear 1; 703. Gear ring; 704. Magnetic block; 705. Separation seat; 706. Handle; 8. Auxiliary mechanism; 801. Storage column; 802. Extension column; 803. Spring; 804. Folding rod; 805. Auxiliary block; 806. Connecting column; 9. Operation screen. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] A cell suspension separation and purification device, such as Figure 1 As shown, it includes a separation platform 1, the bottom end of the separation platform 1 is fixedly connected with an anti-slip foot 2, the top rear side of the separation platform 1 is hinged with a cover plate 3, and the bottom end of the cover plate 3 is fixedly connected with a flip mechanism 4, the rear side of the separation platform 1 is provided with a storage groove 5, the top of the separation platform 1 is provided with a mounting groove 6, and the interior of the mounting groove 6 is movably connected with a separation mechanism 7, the top of the separation mechanism 7 is fixedly connected with an auxiliary mechanism 8, and the front side of the separation platform 1 is fixedly connected with an operation screen 9.

[0029] When in use, first, the cover plate 3 is driven to flip upwards through the flip mechanism 4. This device can make it more convenient for personnel to operate and can effectively prevent the cover plate 3 from loosening, thereby improving the efficiency during use. After that, the test tube containing the cell suspension can be inserted into the separation seat 705, and the separation mechanism 7 can be controlled to separate and purify the cell suspension. After the work is completed, this device can take out the separation seat 705 through the handle 706, so as to facilitate personnel to clean and disinfect and prevent the cell suspension from being contaminated when used next time. In the process of controlling the rotation of the separation mechanism 7, the auxiliary mechanism 8 will cover the top of the test tube under the action of centrifugal force, thereby preventing the test tube cover from falling off during the work and affecting the use of personnel.

[0030] like Figure 5-6 As shown, the separation mechanism 7 includes a motor 701, a gear 702, a gear ring 703, a magnet 704, a separation seat 705 and a handle 706. The output end of the motor 701 is fixedly connected to the axis of the gear. There are multiple magnets 704, and the magnets 704 are all fixedly connected to the inner wall of the magnetic ring. The gear ring 703 is meshed with the gear. The outer wall of the separation seat 705 is provided with multiple slots, and the slots are consistent with the magnets 704. The separation seat 705 is rotatably connected to the inside of the mounting slot 6. The motor 701 is fixedly connected to the inside of the mounting slot 6. The top of the separation seat 705 is fixedly connected with a connecting column 806. A separation slot is provided inside the top of the separation seat 705. The magnet 704 is adsorbed with the slot, and the handle 706 is hinged to the top of the separation seat 705.

[0031] Insert the test tube containing the cell suspension into the separation seat 705, and control the motor 701 to rotate at the same time. When the motor 701 rotates, it will drive the gear ring 703 to rotate through the gear 702. At this time, the gear ring 703 will drive the separation seat 705 to rotate, so as to separate and purify the cell suspension. After the work is completed, the separation seat 705 can be taken out by the handle 706, so as to facilitate the personnel to clean and disinfect, and prevent the cell suspension from being contaminated when used next time.

[0032] like Figure 4-6As shown, the auxiliary mechanism 8 includes a storage column 801, an extension column 802, a spring 803, a folding rod 804, an auxiliary block 805 and a connecting column 806. The storage column 801 is provided with multiple ones, one end of the storage column 801 is fixedly connected to the outer wall of the connecting column 806, the extension column 802 is movably connected to the inside of the storage column 801, one end of the spring 803 is fixedly connected to the inner wall of the storage column 801, and the other end of the spring 803 is fixedly connected to one end of the extension column 802, the other end of the extension column 802 is fixedly connected to one side of the auxiliary block 805, the two ends of the folding rod 804 are respectively hinged to the outer wall of the other end of the extension column 802, the bottom end of the connecting column 806 is fixedly connected to the top of the separation seat 705, and the other side of the auxiliary block 805 is interactively connected to the inner wall of the top of the separation seat 705.

[0033] In the process of controlling the rotation of the separation mechanism 7, the extension column 802 will protrude from the inside of the storage column 801 under the action of centrifugal force, so that the storage column 801 drives the auxiliary block 805 to cover the top of the test tube, thereby preventing the test tube cover from falling off during the operation and affecting the use of personnel.

[0034] like Figure 2-3 As shown, the flip mechanism 4 includes a motor 2 401, a push plate 402, a screw 403, a tooth plate 404 and a gear 2 405, the output end of the motor 2 401 is fixedly connected to one end of the screw 403, one side of the push plate 402 is threadedly connected to the outer wall of the screw 403, and the top of the other side of the push plate 402 is fixedly connected to one end of the tooth plate 404, the tooth plate 404 is provided with two left-right symmetrical ones, and the tooth plate 404 is movably connected to the bottom of the gear 2 405, the tooth plate 404 is meshed with the gear 2 405, the push plate 402 is movably connected to the inside of the storage groove 5, the tooth plate 404 is slidably connected to the inside of the top of the storage groove 5, the gear 2 405 is fixedly connected to one side of the bottom end of the cover plate 3, and the motor 2 401 is fixedly connected to the outer wall of the separation table 1.

[0035] Control motor 2 401 to rotate. When motor 2 401 rotates, it drives push plate 402 to store the inside of storage slot 5 through screw 403. At this time, push plate 402 drives gear 2 405 to rotate through tooth plate 404. When gear 2 405 rotates, it drives cover plate 3 to flip upward. This device can make operation more convenient for personnel, and can effectively prevent cover plate 3 from loosening, thereby improving efficiency during use.

[0036] Here’s how it works:

[0037] When in use, first, control the motor 2 401 to rotate. When the motor 2 401 rotates, it will drive the push plate 402 to store the inside of the storage slot 5 through the screw 403. At this time, the push plate 402 will drive the gear 2 405 to rotate through the tooth plate 404. When the gear 2 405 rotates, it will drive the cover plate 3 to flip upward. This device can be more convenient for personnel to operate, and can effectively prevent the cover plate 3 from loosening, thereby improving the efficiency during use. After that, the test tube containing the cell suspension can be inserted into the separation seat 705, and the motor 1 701 can be controlled to rotate at the same time. When the motor 1 701 rotates, The gear ring 703 will be driven to rotate through the gear 1 702, and the gear ring 703 will drive the separation seat 705 to rotate, so as to separate and purify the cell suspension. After the work is completed, the separation seat 705 can be taken out through the handle 706, so as to facilitate the personnel to clean and disinfect, and prevent the cell suspension from being contaminated when it is used next time. In the process of controlling the rotation of the separation mechanism 7, the extension column 802 will be extended from the inside of the storage column 801 under the action of centrifugal force, so that the storage column 801 drives the auxiliary block 805 to cover the top of the test tube, so as to prevent the test tube cover from falling off during the work and affecting the use of personnel.

[0038] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments, and the above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, and these changes and improvements all fall within the scope of the present invention to be protected.

Claims

1. A cell suspension separation and purification device, comprising a separation station (1), characterized in that: The bottom end of the separation platform (1) is fixedly connected to an anti-slip foot (2); the top rear side of the separation platform (1) is hinged with a cover plate (3), and the bottom end of the cover plate (3) is fixedly connected to a flip mechanism (4); the rear side of the separation platform (1) is provided with a storage groove (5); the top of the separation platform (1) is provided with a mounting groove (6), and the interior of the mounting groove (6) is movably connected to a separation mechanism (7); the top of the separation mechanism (7) is fixedly connected to an auxiliary mechanism (8); and the front side of the separation platform (1) is fixedly connected to an operation screen (9).

2. A cell suspension separation and purification device according to claim 1, characterized in that: The separation mechanism (7) comprises a motor (701), a gear (702), a gear ring (703), a magnetic block (704), a separation seat (705) and a handle (706); the output end of the motor (701) is fixedly connected to the axis of the gear; a plurality of magnetic blocks (704) are provided, and the magnetic blocks (704) are all fixedly connected to the inner wall of the magnetic ring; the gear ring (703) is meshed with the gear; a plurality of slots are provided on the outer wall of the separation seat (705), and the slots are matched with the magnetic blocks (704).

3. A cell suspension separation and purification device according to claim 2, characterized in that: The separation seat (705) is rotatably connected to the inside of the installation groove (6), the motor 1 (701) is fixedly connected to the inside of the installation groove (6), and the top end of the separation seat (705) is fixedly connected with a connecting column (806).

4. A cell suspension separation and purification device according to claim 2, characterized in that: A separation slot is provided inside the top of the separation seat (705), the magnetic block (704) is attracted to the slot, and the handle (706) is hinged to the top of the separation seat (705).

5. The cell suspension separation and purification device according to claim 1, characterized in that: The auxiliary mechanism (8) comprises a storage column (801), an extension column (802), a spring (803), a folding rod (804), an auxiliary block (805) and a connecting column (806). The storage column (801) is provided with a plurality of them, one end of the storage column (801) is fixedly connected to the outer wall of the connecting column (806), the extension column (802) is movably connected to the inside of the storage column (801), one end of the spring (803) is fixedly connected to the inner wall of the storage column (801), and the other end of the spring (803) is fixedly connected to one end of the extension column (802), and the other end of the extension column (802) is fixedly connected to one side of the auxiliary block (805).

6. A cell suspension separation and purification device according to claim 5, characterized in that: The two ends of the folding rod (804) are respectively hinged to the outer wall of the other end of the extension column (802), the bottom end of the connecting column (806) is fixedly connected to the top of the separation seat (705), and the other side of the auxiliary block (805) is interactively connected to the inner wall of the top of the separation seat (705).

7. The cell suspension separation and purification device according to claim 1, characterized in that: The flip cover mechanism (4) comprises a second motor (401), a push plate (402), a screw (403), a tooth plate (404) and a second gear (405), wherein the output end of the second motor (401) is fixedly connected to one end of the screw (403), one side of the push plate (402) is threadedly connected to the outer wall of the screw (403), and the top end of the other side of the push plate (402) is fixedly connected to one end of the tooth plate (404), and the tooth plate (404) is provided with two left-right symmetrical ones, and the tooth plate (404) is movably connected to the bottom of the second gear (405).

8. A cell suspension separation and purification device according to claim 7, characterized in that: The tooth plate (404) is meshed with gear 2 (405), the push plate (402) is movably connected to the inside of the storage groove (5), the tooth plate (404) is slidably connected to the inside of the top end of the storage groove (5), the gear 2 (405) is fixedly connected to one side of the bottom end of the cover plate (3), and the motor 2 (401) is fixedly connected to the outer wall of the separation table (1).

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