Device for rapidly detecting serum prolactin in peripheral blood

By using a weight sensor and an electromagnetic slider in the serum detection device to adjust the centrifugal force, combining the trigger block and connecting rod to adjust the test tube position and the amount of enzymatic reaction luminescent agent, the problems of cumbersome serum detection steps and uneven centrifugal in the prior art are solved, and fast and accurate serum prolactin detection is achieved.

CN119827259APending Publication Date: 2025-04-15NANJING DRUM TOWER HOSPITAL +1
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Patent Information

Application Number
CN202510089716.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-21
Publication Date
2025-04-15

AI Technical Summary

Technical Problem

The existing serum detection devices have complicated steps when detecting prolactin in serum, with a long detection cycle, and centrifugation is uneven due to differences in blood viscosity, which affects the detection results.

Method used

A device for rapid detection of serum prolactin in peripheral blood was designed, using a weight sensor to measure blood weight, judge the viscosity based on the weight, and adjust the centrifugal force through an electromagnetic slider to ensure the synchronous centrifugation of blood of different viscosity. At the same time, the test tube position is adjusted by adjusting the trigger block and connecting rod, and the amount of enzymatic reaction luminescent agent is added adaptively.

Benefits of technology

It realizes synchronously and accurately detecting prolactin in the same batch of serum without detecting blood viscosity, shortening the detection time, improving the detection efficiency and patient compliance, and ensuring serum quality.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of serum detection, in particular to a device for rapidly detecting serum prolactin through peripheral blood. Comprising a shell in which a centrifugal disc is mounted; the weight sensor is fixedly connected to the centrifugal disc, a sliding frame is connected to the weight sensor in a sliding mode, the sliding frame is connected with an electromagnetic sliding block in a sliding mode through an electromagnetic sliding rail, the electromagnetic sliding block is fixedly connected with an elastic telescopic rod, and the telescopic end of the elastic telescopic rod is fixedly connected with a fixed block; and the fixed frame is connected to the sliding frame in a sliding manner. The weight of blood is measured through the weight sensor, the viscosity of the blood is judged according to the weight of the blood when the viscosity of the blood in the same batch is different, the blood with the higher viscosity is closer to the edge position of the centrifugal disc, it is ensured that the blood with the different viscosities in the same batch can be centrifuged at the same time, and the blood concentration is increased. Further, the influence on the quality of the serum caused by impurities in the serum due to excessive centrifugation or insufficient centrifugation is prevented.
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Description

Technical Field

[0001] The invention relates to the technical field of serum detection, in particular to a device for rapidly detecting serum prolactin from peripheral blood. Background Art

[0002] Peripheral blood refers to the blood circulating in the human vascular system. Serum is the liquid part separated from the blood that does not contain coagulation factors and blood cells. Prolactin is a polypeptide hormone secreted by the anterior pituitary gland. Its main function is to promote breast development and milk production. The serum prolactin detection device is a device used to measure the level of prolactin in the blood. The detection method includes chemiluminescent immunoassay. Chemiluminescent immunoassay is a type of labeled antibody technology. The catalytic action of the labeled enzyme can be used to make the luminescent agent added to the serum emit light, and then the photometry can be used to detect the luminescence to obtain the prolactin content in the serum.

[0003] When detecting prolactin in serum, the existing detection device must go through the steps of blood collection, coagulation, centrifugation, reagent preparation and labeled luminescence. The detection cycle itself is relatively long. In addition, the amount of blood collected and the blood viscosity of different people may vary. When centrifuging the serum, batches of serum need to be processed at the same time, which will cause the more viscous blood to not be centrifuged properly, resulting in insufficient separation of serum from cellular components and fibrin in the blood, causing residual red blood cells and even hemolysis. The thinner blood will be over-centrifuged, resulting in the separation of lipids in the serum, forming an obvious lipid blood layer, which affects the operation of the detection instrument. This means that the viscosity of the blood needs to be tested before the serum test, making the serum test steps cumbersome and seriously affecting the patient's compliance with the serum test. Summary of the invention

[0004] In order to overcome the shortcomings pointed out in the above background technology, the present invention provides a device for rapid detection of serum prolactin in peripheral blood.

[0005] The technical solution is: a device for rapid detection of serum prolactin in peripheral blood, comprising: A housing, the housing being rotatably connected to a cover, and a centrifugal disk electrically connected to an external power source being installed in the housing; A weight sensor having a plurality of circumferential portions, all of which are fixedly connected to the centrifugal disk; a sliding frame is slidably connected to the weight sensor; a first elastic member is fixedly connected between the weight sensor and the sliding frame; the sliding frame is slidably connected to an electromagnetic slider electrically connected to the weight sensor via an electromagnetic slide rail; the electromagnetic slider is fixedly connected to an elastic telescopic rod; and a fixed block is fixedly connected to the telescopic end of the elastic telescopic rod; The number of the fixed frames is the same as that of the fixed blocks, and they are respectively slidably connected in adjacent sliding frames. A second elastic member is fixedly connected between the fixed frame and the adjacent sliding frame.

[0006] Preferably, the fixing block is provided with at least two grooves for limiting the position of the test tube.

[0007] As a preferred embodiment, it also includes: The weight blocks, the number of which is the same as the number of the fixing frames, are respectively fixed to adjacent fixing frames.

[0008] As a preferred embodiment, it also includes: The number of the flexible pads is the same as that of the fixing frames, and they are respectively fixed to one side of the adjacent fixing frames close to the adjacent fixing blocks. The maximum distance between the side of the fixing frames close to the adjacent fixing blocks and two adjacent grooves is X, the diameter of the test tube is Y, and X>Y.

[0009] As a preferred embodiment, it also includes: Support frames, the number of which is the same as the number of the electromagnetic sliders, are respectively fixed to adjacent electromagnetic sliders, and the support frames are slidably connected to the first trigger blocks; The number of the second trigger blocks is the same as that of the first trigger blocks, and they are respectively fixed to the telescopic ends of the elastic telescopic rods. The second trigger blocks are squeezed and matched with the adjacent first trigger blocks.

[0010] As a preferred embodiment, it also includes: The number of connecting rods is the same as that of the supporting frames, and they are respectively slidably and rotatably connected to the adjacent supporting frames, and the connecting rods are rotatably connected to the adjacent first trigger blocks, and the connecting rods are provided with a plurality of limiting grooves distributed in a straight line; The number of the limit blocks is the same as that of the support frames, and they are slidably connected to adjacent support frames respectively. The limit grooves are limitedly matched with the limit blocks, and a third elastic member is fixedly connected between the limit blocks and the adjacent support frames.

[0011] As a preferred embodiment, it also includes: The first pipeline is fixedly connected to the cover and communicated with an external feeding device. The first pipeline is communicated with the second pipeline. The second pipeline is sealed and slidable and communicated with the third pipeline. A fourth elastic member is fixedly connected between the third pipeline and the second pipeline. The third pipeline is installed with a regulating valve. The regulating valve and the second pipeline are driven by a rack and pinion.

[0012] As a preferred embodiment, it also includes: A first extrusion block, fixedly connected to the third pipe; The number of the second extrusion blocks is the same as that of the fixed blocks, and they are respectively fixed to the adjacent fixed blocks. The second extrusion blocks are extrusion-matched with the first extrusion blocks.

[0013] As a preferred embodiment, it also includes: a sliding pipe, sealingly and slidingly connected in the third pipe, the sliding pipe is in communication with the third pipe, and a fifth elastic member is fixedly connected between the sliding pipe and the third pipe; The blocking block is fixedly connected to the sliding pipe.

[0014] Preferably, the minimum distance between the second extrusion block and adjacent grooves on the adjacent fixed block projected on the centrifugal disk is A, and the minimum distance between the second extrusion block and the axis of the sliding pipe projected on the centrifugal disk is B, and A=B.

[0015] The present invention has the following advantages: 1. The present invention measures the weight of blood by a weight sensor. When the viscosity of blood in the same batch is different, the viscosity is determined according to the blood weight, and the blood with higher viscosity is made closer to the edge of the centrifugal disk, ensuring that blood with different viscosities in the same batch can be centrifuged at the same time, thereby preventing impurities in the serum due to excessive centrifugation or inadequate centrifugation, which affects the quality of the serum; 2. The first trigger block squeezes the second trigger block, thereby adjusting the position of the test tube through the fixed block, changing the position of the test tube on the centrifugal disk, and realizing the separation of different centrifugal forces of different blood volumes in the same batch without detecting the blood volume, so as to speed up the detection of prolactin in serum and ensure the centrifugal effect of different blood volumes: 3. The amount of the enzymatic reaction luminescent agent added to the test tube is adjusted by the regulating valve, and the amount of the enzymatic reaction luminescent agent added to each test tube is adaptively adjusted, so that the amount of the enzymatic reaction luminescent agent added can be directly added to the serum without additional calculation, thereby reducing the time for operators to detect prolactin in serum, reducing the waiting time for serum testing of patients, and improving patients' compliance with serum testing. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention; Figure 2 It is a three-dimensional structural cross-sectional view of the housing and the cover of the present invention; Figure 3 It is a schematic diagram of the three-dimensional structure of the weight sensor of the present invention; Figure 4 It is a schematic diagram of the three-dimensional structure of the sliding frame of the present invention; Figure 5 It is a schematic diagram of the three-dimensional structure of the fixing frame of the present invention; Figure 6 It is a three-dimensional structural cross-sectional view of the sliding frame of the present invention; Figure 7 It is a three-dimensional structural cross-sectional view of the support frame of the present invention; Figure 8It is a three-dimensional structural cross-sectional view of the first pipeline, the second pipeline and the third pipeline of the present invention; Fig. 9 It is a schematic diagram of the three-dimensional structure of the sliding pipe and the blocking block of the present invention.

[0017] The numbers in the figure are as follows: 1-housing, 101-cover, 102-centrifugal disc, 2-weight sensor, 201-sliding frame, 202-electromagnetic slider, 203-elastic telescopic rod, 204-fixed block, 205-fixed frame, 3-weight block, 4-flexible pad, 5-support frame, 501-first trigger block, 502-second trigger block, 6-connecting rod, 601-limiting groove, 602-limiting block, 7-first pipeline, 701-second pipeline, 702-third pipeline, 703-regulating valve, 8-first extrusion block, 801-second extrusion block, 9-sliding pipeline, 901-blocking block. DETAILED DESCRIPTION

[0018] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below.

[0019] In order to reduce the cumbersome steps of prolactin detection in serum, the synchronous and accurate detection of serum in the same batch can be achieved without testing blood viscosity, so as to speed up the detection of prolactin in serum. Figure 1-Figure 6As shown, the present invention proposes a device for rapid detection of serum prolactin from peripheral blood, comprising: a shell 1, a cover 101 rotatably connected to the shell 1, a control terminal not shown in the figure is arranged on the outside of the shell 1, the cover 101 is sealed and matched with the shell 1, and is used to reduce the influence of the external environment on the serum during centrifugal separation to prevent the serum from being contaminated by impurities during centrifugal separation, a centrifugal disk 102 electrically connected to an external power supply is installed in the shell 1, the centrifugal disk 102 is electrically connected to the control terminal, and an operator can open the centrifugal disk 102 through the control terminal to rotate the centrifugal disk 102 and drive the parts thereon to rotate; a weight sensor 2, having a plurality of circumferentially connected to the centrifugal disk 102, the weight sensor 2 is electrically connected to the control terminal, a sliding frame 201 is slidably connected to the weight sensor 2, a first elastic member is fixedly connected between the weight sensor 2 and the sliding frame 201, wherein the first elastic member is a compression spring, and the compression amount of the first elastic member is positively correlated with the gravity of the sliding frame 201 and the parts thereon and the test tube, and is used to measure the weight of the device. The weight of the test tube containing blood, and the operator can connect the weight sensor 2 through the mobile phone Bluetooth to monitor and record the weight of the blood in the test tube in real time, so as to actively adjust the displacement of the electromagnetic slider 202 through the control terminal, the sliding frame 201 is slidably connected to the electromagnetic slider 202 electrically connected to the weight sensor 2 through the electromagnetic slide rail, the electromagnetic slider 202 is electrically connected to the control terminal, the electromagnetic slider 202 is fixedly connected to the elastic telescopic rod 203, the telescopic end of the elastic telescopic rod 203 is fixedly connected to the fixed block 204, the fixed block 204 is provided with two grooves for limiting the test tube, one of which is used to load blood at the initial time, and the other is used to load the separated serum; the fixed frame 205, the number of which is the same as the number of the fixed blocks 204, is respectively slidably connected to the adjacent sliding frame 201, and a second elastic member is fixedly connected between the fixed frame 205 and the adjacent sliding frame 201, wherein the second elastic member is a tension spring, and the test tube is clamped between the fixed block 204 and the adjacent fixed frame 205 through the second elastic member.

[0020] Reference Figure 6 As shown, it also includes: weight blocks 3, the number of which is the same as the number of the fixing frames 205, which are respectively fixed to adjacent fixing frames 205, and are used for the weight blocks 3 to squeeze the fixing frames 205 under the influence of centrifugal force when the centrifugal disk 102 rotates rapidly, so that the fixing frames 205 press the test tubes and stably clamp the test tubes between the fixing blocks 204 and the adjacent fixing frames 205.

[0021] Reference Figure 5 and Figure 6As shown, it also includes: flexible pads 4, the number of which is the same as the number of fixing frames 205, which are respectively fixed to the side of the adjacent fixing frames 205 close to the adjacent fixing blocks 204, and the upper side of the flexible pads 4 is provided with an inclined surface to facilitate the insertion of the test tube between the fixing block 204 and the adjacent fixing frame 205. The farthest distance between the side of the fixing frame 205 close to the adjacent fixing block 204 and the two adjacent grooves is X, the diameter of the test tube is Y, and X>Y, so that the test tube can be smoothly placed between the fixing block 204 and the adjacent fixing frame 205.

[0022] In this embodiment, after the serum is centrifuged, the operator manually extracts the upper serum in the test tube and manually adds the enzymatic reaction luminescent agent to the serum. Finally, the luminescent agent in the test tube is detected by a spectrophotometer to obtain the prolactin content in the serum. The operator can construct a nano-magnetic particle containing nanoparticles to encapsulate the antigen epitope (the antigen epitope can bind to the prolactin in the serum), so that the prolactin in the serum can contact the enzymatic reaction luminescent agent at a faster speed and quickly develop, thereby shortening the prolactin luminescent reaction time, thereby improving the prolactin detection efficiency. The operator can also add nano-antibodies to the serum to bind to the prolactin in the serum. The nano-antibodies have the characteristics of high penetrability and high affinity, so that the nano-antibodies can quickly bind to the prolactin in the serum, thereby improving the efficiency of prolactin detection in the serum.

[0023] Workflow: When the operator needs to use the device to detect prolactin in serum, the operator opens the cover 101 by turning it, and then places a number of test tubes containing blood between a groove of an adjacent fixed block 204 and an adjacent flexible pad 4, and then covers the cover 101. The sliding frame 201 and its parts and test tubes are pressed downward by gravity to press the first elastic member. The operator turns on the weight sensor 2 through the control terminal, so that the weight sensor 2 feels the pressure of the parts on it. The weight sensor 2 turns on the electromagnetic slider 202 through the control terminal. The weight sensor 2 adjusts the movement of the electromagnetic slider 202 according to the pressure it receives. The more blood The lighter the test tube is, the more it moves toward the axis of the centrifugal disk 102, so that the lighter blood (the lighter test tube has less blood volume or lower viscosity) is closer to the axis of the centrifugal disk 102, and the closer to the edge of the centrifugal disk 102, the greater the centrifugal force, so that the centrifugal force of the same batch of blood is different, and the same batch of serum with different viscosities can be separated with different centrifugal forces without detecting the viscosity of the blood, so as to speed up the detection of prolactin in the serum and ensure that the blood with different viscosities in the same batch can be centrifuged at the same time, thereby preventing impurities in the serum due to excessive centrifugation or insufficient centrifugation, which affects the quality of the serum.

[0024] During the rotation of the centrifugal disk 102 , the weight block 3 is affected by the centrifugal force to drive the fixing frame 205 to move toward the fixing block 204 , so that the fixing frame 205 presses the test tube and stably clamps the test tube between the fixing block 204 and the adjacent fixing frame 205 .

[0025] When the serum separation is completed, the operator closes the centrifugal disk 102, the weight sensor 2 and the electromagnetic slider 202 through the control terminal, then opens the cover 101, extracts the serum in the test tube, puts the serum into the test tube, and manually adds the enzymatic reaction luminescent agent into the serum, uses a spectrophotometer to detect the luminescent agent in the test tube to know the prolactin content in the serum, and finally cleans the test tube for the next use.

[0026] In order to speed up the serum testing process without requiring the operator to pre-adjust the blood volume, Figure 6 and Figure 7 As shown, the present invention also includes: support frames 5, the number of which is the same as the number of electromagnetic sliders 202, which are respectively fixed to adjacent electromagnetic sliders 202, and the support frames 5 are slidably connected with first trigger blocks 501; second trigger blocks 502, the number of which is the same as the number of first trigger blocks 501, which are respectively fixed to the telescopic ends of the elastic telescopic rod 203, and the opposite sides of the first trigger block 501 and the adjacent second trigger block 502 are both provided with inclined surfaces, and the second trigger block 502 is squeezed and matched with the adjacent first trigger block 501, and is used for squeezing the adjacent second trigger block 502 to move when the first trigger block 501 moves downward, thereby driving the telescopic end of the elastic telescopic rod 203 to extend.

[0027] Reference Figure 7 As shown, it also includes: connecting rods 6, the number of which is the same as the number of support frames 5, which are respectively slidably and rotatably connected to adjacent support frames 5, the connecting rod 6 is rotatably connected to the adjacent first trigger block 501, and the connecting rod 6 is provided with a plurality of limit grooves 601 distributed in a straight line; limit blocks 602, the number of which is the same as the number of support frames 5, which are respectively slidably connected to the adjacent support frames 5, the limit grooves 601 and the limit blocks 602 are limitedly matched, and when the limit block 602 is inserted into a limit groove 601, the connecting rod 6 can only move downward in one direction, and when the connecting rod 6 is rotated 90°, the limit block 602 loses contact with the limit groove 601, and the connecting rod 6 can slide up and down freely, and a third elastic member is fixedly connected between the limit block 602 and the adjacent support frame 5, wherein the third elastic member is a compression spring.

[0028] Workflow: Before the operator separates the serum, the operator can adjust the height of the connecting rod 6 according to the amount of blood in the test tube. The operator moves the connecting rod 6 up and down to make the first trigger block 501 move up and down. If the first trigger block 501 moves downward, the second trigger block 502 moves toward the fixed block 204. If the first trigger block 501 moves upward, the second trigger block 502 moves away from the fixed block 204, thereby adjusting the position of the test tube through the fixed block 204, changing the position of the test tube on the centrifugal disk 102, making the centrifugal force of the same batch of blood different, and realizing the separation of different centrifugal forces of multiple blood volumes of the same batch without detecting the blood volume, so as to speed up the detection speed of prolactin in serum and ensure the centrifugal effect of different blood volumes.

[0029] When the serum separation is completed, the operator manually rotates the connecting rod 6, and the connecting rod 6 drives all the limit grooves 601 thereon to rotate, and the limit block 602 loses contact with the limit groove 601, and the connecting rod 6 can slide up and down freely to freely adjust the height position of the connecting rod 6.

[0030] In order to reduce the time required for serum testing, the following examples combine serum separation and enzymatic reaction, and automatically adjust the amount of enzymatic reaction luminescent agent added according to the blood volume and viscosity. Figure 2-Figure 4 and Figure 8 As shown, the present invention also includes: a first pipeline 7, which is fixedly connected to the cover 101 and communicated with an external feeding device, the first pipeline 7 is communicated with a second pipeline 701, the second pipeline 701 is sealed and slidable and is communicated with a third pipeline 702, the first pipeline 7, the second pipeline 701 and the third pipeline 702 are all filled with an enzymatic reaction luminescent agent, the external feeding device is electrically connected to the control terminal, and is used to continuously supply the enzymatic reaction luminescent agent to the third pipeline 702, a fourth elastic member is fixedly connected between the third pipeline 702 and the second pipeline 701, and a regulating valve 703 is installed on the third pipeline 702, and the regulating valve 703 and the second pipeline 701 are driven by a gear rack to Figure 1 The top view is used as the rotation reference, and the internal flow rate of the regulating valve 703 gradually decreases during the counterclockwise rotation of the regulating valve 703.

[0031] Reference Figure 3 and Figure 8 As shown, it also includes: a first extrusion block 8, which is fixedly connected to the third pipe 702; second extrusion blocks 801, the number of which is the same as the number of fixed blocks 204, which are respectively fixedly connected to adjacent fixed blocks 204, the cross-sections of the first extrusion block 8 and all the second extrusion blocks 801 are isosceles trapezoids, and the maximum distance between the inclined surfaces on both sides of the second extrusion block 801 is less than the diameter of the test tube, the second extrusion block 801 is extruded and matched with the first extrusion block 8, and of the two test tubes on the fixed block 204, the test tube close to the adjacent second extrusion block 801 is initially an empty test tube for loading the separated serum.

[0032] Reference Figure 8 and Fig. 9 As shown, it also includes: a sliding pipe 9, which is sealed and slidably connected in the third pipe 702, the sliding pipe 9 is communicated with the third pipe 702, and a fifth elastic member is fixedly connected between the sliding pipe 9 and the third pipe 702, wherein the fifth elastic member is a compression spring, and the aperture of the sliding pipe 9 is much smaller than the aperture of the third pipe 702, which is used to increase the flow pressure of the enzymatic reaction luminescent agent in the sliding pipe 9; a blocking block 901, which is fixedly connected to the sliding pipe 9, and the blocking block 901 is an inverted flexible truncated cone block, which is used to block the test tube mouth, the minimum distance between the second extrusion block 801 and the adjacent grooves on the adjacent fixed block 204 projected on the centrifugal disk 102 is A, and the minimum distance between the second extrusion block 801 and the axis of the sliding pipe 9 projected on the centrifugal disk 102 is B, A=B, which is used to align the axis of the test tube near the adjacent second extrusion block 801 with the axis of the sliding pipe 9 after the second extrusion block 801 contacts and aligns with the second extrusion block 801, so that the enzymatic reaction luminescent agent can be accurately added to the test tube.

[0033] Workflow: After the serum separation is completed, the operator controls the centrifugal disk 102 to rotate slowly through the control terminal, and the centrifugal disk 102 drives the parts thereon to rotate. When a second extrusion block 801 moves to contact the first extrusion block 8, the first extrusion block 8 is squeezed by the second extrusion block 801 and moves in the direction of the first pipe 7. The first extrusion block 8 drives the third pipe 702 to move, so that the fourth elastic member contracts, and the third pipe 702 slides in the second pipe 701. After a second extrusion block 801 moves to align with the first extrusion block 8, the operator closes the centrifugal disk 102 through the control terminal, and controls the opening of the external feeding device through the control terminal, so that the enzymatic reaction luminescent agent in the second pipe 701 flows into the third pipe 702, and then flows into the sliding pipe 9. Since the aperture of the sliding pipe 9 is much smaller than the aperture of the third pipe 702, a part of the enzymatic reaction luminescent agent will squeeze the sliding pipe 9 to move downward, so that the fifth elastic member is compressed, the sliding pipe 9 moves into the test tube, and the blocking block 901 blocks the test tube mouth to prevent serum splashing when the enzymatic reaction luminescent agent is injected.

[0034] When the first squeezing block 8 is squeezed by the second squeezing block 801 and moves toward the first pipe 7, the position of the second squeezing block 801 is driven to move by the fixed block 204. The less the amount of blood or the lower the blood viscosity, the closer the second squeezing block 801 is to the position of the first pipe 7, so that the regulating valve 703 is closer to the first pipe 7, and the regulating valve 703 drives the gear thereon to move along the rack. The greater the angle of the counterclockwise rotation of the regulating valve 703, the less the flow volume of the regulating valve 703, and the test tube closer to the first pipe 7 has less serum volume, and the amount of enzymatic reaction luminescent dose added to each test tube is adaptively adjusted, so that the amount of enzymatic reaction luminescent dose added can be directly added to the serum without additional calculation, thereby reducing the time for operators to detect prolactin in serum, reducing the waiting time for patient serum testing, and improving patient compliance with serum testing.

[0035] When the serum separation is completed, the operator closes the centrifugal disc 102, the weight sensor 2, the electromagnetic slider 202 and the external feeding device through the control terminal, then opens the lid 101, uses a spectrophotometer to detect the luminescent agent in the test tube to find out the prolactin content in the serum, and finally cleans the test tube for the next use. Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to replace some of the technical features therein by equivalents. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A device for rapid detection of serum prolactin in peripheral blood, characterized in that: include: A housing (1), the housing (1) being rotatably connected to a cover (101), and a centrifugal disc (102) electrically connected to an external power source being installed in the housing (1); The weight sensor (2) has a plurality of circumferentially disposed weight sensors, all of which are fixedly connected to the centrifugal disc (102); a sliding frame (201) is slidably connected to the weight sensor (2); a first elastic member is fixedly connected between the weight sensor (2) and the sliding frame (201); the sliding frame (201) is slidably connected to an electromagnetic slider (202) electrically connected to the weight sensor (2) via an electromagnetic slide rail; the electromagnetic slider (202) is fixedly connected to an elastic telescopic rod (203); and a fixed block (204) is fixedly connected to the telescopic end of the elastic telescopic rod (203); The number of the fixed frames (205) is the same as the number of the fixed blocks (204), and they are respectively slidably connected to adjacent sliding frames (201), and a second elastic member is fixedly connected between the fixed frame (205) and the adjacent sliding frame (201).

2. The device for rapid detection of serum prolactin by peripheral blood according to claim 1, characterized in that: The fixing block (204) is provided with at least two grooves for limiting the position of the test tube.

3. The device for rapid detection of serum prolactin by peripheral blood according to claim 1, characterized in that include: The weight blocks (3) are the same in number as the fixing frames (205) and are respectively fixedly connected to adjacent fixing frames (205).

4. The device for rapid detection of serum prolactin by peripheral blood according to claim 3, characterized in that include: The number of the flexible pads (4) is the same as the number of the fixing frames (205), and they are respectively fixed to a side of an adjacent fixing frame (205) close to an adjacent fixing block (204), the maximum distance between a side of the fixing frame (205) close to an adjacent fixing block (204) and two adjacent grooves is X, the diameter of the test tube is Y, and X>Y.

5. The device for rapid detection of serum prolactin by peripheral blood according to claim 1, characterized in that include: Support frames (5), the number of which is the same as the number of the electromagnetic sliders (202), respectively fixed to adjacent electromagnetic sliders (202), and the support frames (5) are slidably connected to first trigger blocks (501); The number of the second trigger blocks (502) is the same as that of the first trigger blocks (501), and they are respectively fixed to the telescopic ends of the elastic telescopic rods (203), and the second trigger blocks (502) are pressed and matched with the adjacent first trigger blocks (501).

6. The device for rapid detection of serum prolactin by peripheral blood according to claim 5, characterized in that include: The number of connecting rods (6) is the same as the number of the supporting frames (5), and they are respectively slidably and rotationally connected to adjacent supporting frames (5), the connecting rods (6) are rotationally connected to adjacent first trigger blocks (501), and the connecting rods (6) are provided with a plurality of limiting grooves (601) distributed in a straight line; The number of the limit blocks (602) is the same as the number of the support frames (5), and they are respectively slidably connected in adjacent support frames (5); the limit grooves (601) and the limit blocks (602) are limitedly matched; and a third elastic member is fixedly connected between the limit blocks (602) and the adjacent support frames (5).

7. The device for rapid detection of serum prolactin by peripheral blood according to claim 1, characterized in that include: The first pipe (7) is fixedly connected to the cover (101) and is connected to an external feeding device. The first pipe (7) is connected to a second pipe (701). The second pipe (701) is sealed and slidable and is connected to a third pipe (702). A fourth elastic member is fixedly connected between the third pipe (702) and the second pipe (701). The third pipe (702) is installed with a regulating valve (703). The regulating valve (703) and the second pipe (701) are connected via a gear rack transmission.

8. The device for rapid detection of serum prolactin by peripheral blood according to claim 7, characterized in that include: A first extrusion block (8) fixedly connected to the third pipe (702); The number of the second extrusion blocks (801) is the same as the number of the fixed blocks (204), and they are respectively fixed to adjacent fixed blocks (204). The second extrusion blocks (801) are extrusion-matched with the first extrusion blocks (8).

9. The device for rapid detection of serum prolactin by peripheral blood according to claim 8, characterized in that include: a sliding pipe (9) sealed and slidably connected in the third pipe (702), the sliding pipe (9) being in communication with the third pipe (702), and a fifth elastic member being fixedly connected between the sliding pipe (9) and the third pipe (702); The blocking block (901) is fixedly connected to the sliding pipe (9).

10. The device for rapid detection of serum prolactin by peripheral blood according to claim 9, characterized in that: The minimum distance between the second extrusion block (801) and adjacent grooves on the adjacent fixed block (204) projected on the centrifugal disk (102) is A, and the minimum distance between the second extrusion block (801) and the axis of the sliding pipe (9) projected on the centrifugal disk (102) is B, and A=B.

Citation Information

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