Tablet granulating and drying device

Abstract

The invention discloses a tablet granulating and drying device, and relates to the technical field of tablet granulating and drying, the tablet granulating and drying device comprises a drying cylinder, a supporting vertical rod is rotatably mounted on the inner bottom wall of a circular truncated cone-shaped closed structure, one end of a material distribution box transversely penetrates through a through hole and is rotatably connected with two side walls in the through hole, and a material collection pipe is rotatably arranged at one end of the material distribution box; the fluted disc is meshed with the annular rack, a continuously-connected corrugated structure is arranged on the upper end face of the annular rack, and the fluted disc is in real-time rolling contact along the surface wall of the corrugated structure of the annular rack. The material turning part can be rotationally adjusted to drive the fluted disc to roll along the upper end of the annular rack, then the material turning pipe is driven to annularly move with the material collecting pipe as the rotating center, the material distributing box can vertically swing around the rotating position in the through hole while rotating in the plane where the material distributing box is located, the material turning depth of the material turning pipe is adjusted, and the positions of tablet particles are changed; therefore, when tablet particles with overlarge thickness are dried at a time, the tablet particles are heated uniformly, and the conditions of drying breakage and adhesion due to insufficient drying are avoided.

Description

Technical Field

[0001] The invention relates to the technical field of tablet granulation and drying, in particular to a tablet granulation and drying device. Background Art

[0002] Tablet granulation and drying is a key step in the production of pharmaceutical preparations. It involves mixing the drug raw materials with other excipients to form granules, and removing moisture from the granules through the drying process to achieve conditions suitable for tableting. Removing moisture from the granules prevents problems such as sticking and cracking during tableting, and improves the stability and shelf life of the tablets.

[0003] In the prior art, the problems that may exist in the tablet granulation drying process mainly include the following: the particles are directly blown by high-temperature hot air for a long time during the drying process, resulting in too high drying temperature, causing the surface of the particles to harden too quickly, and the internal water evaporation generates pressure and breaks. This will affect the drying quality and efficiency; in addition, since the tablet particles are relatively small in size, the number of particles dried at a time is large, the particle stacking thickness is too large, and some particles are located in the middle position. The amount of heat radiation per unit time is different from that of the tablet particles on the outside, that is, the temperature distribution is uneven, which makes it difficult to dry the internal particles and prone to adhesion. Summary of the invention

[0004] The object of the present invention is to provide a tablet granulation and drying device to solve the problems raised in the above background technology.

[0005] To achieve the above object, the present invention provides the following technical solution: a tablet granulation drying device, comprising a drying cylinder, wherein the upper end of the drying cylinder is a feeding opening structure, and the bottom end gradually narrows to a truncated cone-shaped closed structure; A material turning component, the material turning component includes a supporting upright, a material distribution box, a material collection pipe and a plurality of material turning pipes radially arranged along the material collection pipe, the supporting upright is rotatably mounted on the inner bottom wall of the truncated cone-shaped closed structure, the top of the supporting upright is provided with an enlarged end, and the enlarged end is radially provided with a through hole, one end of the material distribution box passes horizontally through the through hole and is rotatably connected to the inner side walls of the through hole, the material collection pipe is rotatably arranged at one end of the material distribution box, an annular rack is provided on the radial inner wall of the drying cylinder near the bottom, a toothed disc is fixed to the end of the material collection pipe, and the toothed disc is meshed with the annular rack; The upper end surface of the annular rack is provided with a continuously connected corrugated structure, and the toothed disc is in real-time rolling contact along the surface wall of the corrugated structure of the annular rack; The material turning component can be rotated and adjusted to drive the toothed disc to roll along the upper end of the annular rack, thereby driving the material turning tube to make an annular motion with the collecting tube as the rotation center. While the material distribution box rotates in the plane where it is located, it can also swing up and down around the rotation position in the through hole to adjust the turning depth of the material turning tube and change the position of the tablet particles.

[0006] In a further embodiment, there is a gap between the end of the material distribution box away from the collecting pipe and the annular rack.

[0007] In a further embodiment, the radial outer wall of the enlarged end is symmetrically provided with two spring sheets located on the upper sides of the two openings of the through hole, and the ends of the spring sheets are against the upper end surface of the material distribution box.

[0008] In a further embodiment, a base is fixed to the bottom wall of the truncated cone type closed structure, a motor is installed in the base, and the output end of the motor rotates through the bottom wall of the truncated cone type closed structure and is fixedly connected to the bottom wall of the supporting pole.

[0009] In a further embodiment, a hot air blower is also installed in the base, and the air outlet of the hot air blower is connected to a duct, and the end of the duct is fixedly connected to a hollow air storage box, and the air storage box is rotatably sleeved on the outer wall of the bottom end of the supporting upright, and a connecting hole is provided on the inner wall of the air storage box, and an air guide channel is axially provided on the supporting upright, and the top opening of the air guide channel extends to the bottom wall of the through hole and is located below the distribution box, and the top opening of the air guide channel is provided with an anti-blocking net, and the bottom opening of the air guide channel is connected to the connecting hole.

[0010] In a further embodiment, the collecting pipe is axially provided with a hollow structure, and the end away from the distribution box is a closed structure, the radial side wall of the collecting pipe is provided with an inlet connected to the material turning pipe, and the distribution box is provided with a discharge hole connected to the hollow structure, and the hollow structure, the inlet and the discharge hole constitute a material guiding channel.

[0011] In a further embodiment, a plurality of diversion holes are provided on both side walls of the material distribution box, and an expansion portion is provided at the connection between the diversion hole and the discharge hole.

[0012] In a further embodiment, two symmetrically distributed opposite material turning tubes are close to each other and have an entry end extending through the feed port into the hollow structure, and the two feed ends are staggered.

[0013] In a further embodiment, a partition is also included, which includes a partition sleeve and a plurality of partitions. An annular extension ring is radially extended at the upper end of the partition sleeve, and a plurality of partitions are arranged in an annular structure on the radial outer wall of the partition sleeve, and the top wall of the partition is connected to the bottom wall of the annular extension ring. A plurality of ventilation holes 1 are opened on the annular extension ring, and a ventilation hole 2 is opened on the edge of the partition sleeve and is opposite to the space between two adjacent partitions. An annular base is fixed to the inner wall of the drying cylinder, and a plurality of partitions are seated on the upper end surface of the annular base, and the partitions are fitted with the inner wall of the drying cylinder to form a plurality of independent chambers. A ventilation hole 3 connected to the chamber is opened on the annular base, and an annular threaded ring is fixed to the upper end surface of the partition sleeve, and the annular threaded ring is threadedly connected to a wind shield.

[0014] In a further embodiment, a high-pressure fan is fixed to the inner top wall of the wind shield, and an air inlet of the high-pressure fan extends to the outside of the top end of the wind shield.

[0015] Compared with the prior art, the present invention has the following beneficial effects: The present invention relates to a tablet granulating and drying device. The material turning component can be rotated and adjusted to drive the toothed disc to roll along the upper end of the annular rack, thereby driving the material turning pipe to make an annular motion with the collecting pipe as the rotation center. While the material distribution box rotates in the plane where it is located, it can also swing up and down around the rotation position in the through hole, adjust the material turning depth of the material turning pipe, and change the position of the tablet particles to ensure that when the tablet particles with too large thickness are dried in a single time, they can be heated evenly to avoid excessive cracking due to excessive drying and adhesion due to insufficient drying. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the main structure of the present invention; Figure 2 It is a partial cross-sectional view of the drying cylinder of the present invention; Figure 3 It is a schematic diagram of the structure of the material turning component of the present invention; Figure 4 It is a partial top view of the material turning component of the present invention; Figure 5 It is a schematic diagram of the partial structure of the material turning component of the present invention; Figure 6 This is a schematic diagram of the relative position distribution of two material turning pipes in the same group of the present invention; Figure 7 It is a partial cross-sectional view of the air storage box of the present invention; Figure 8 It is a schematic diagram of the assembly structure of the partition and the windshield with a half-section structure of the present invention; Fig. 9 It is a schematic diagram of the assembly structure of the partition, the wind shield and the drying cylinder of the half-section structure of the present invention; Fig.10 It is a schematic diagram of the assembly structure of the separator and the annular base of the present invention.

[0017] In the figure: 1. drying cylinder; 11. annular base; 12. annular rack; 2. separating sleeve; 21. annular threaded ring; 22. partition; 3. wind shield; 4. high-pressure fan; 5. base; 6. hot air blower; 61. air storage box; 7. supporting pole; 71. enlarged end; 72. material distribution box; 73. spring; 74. collecting pipe; 741. toothed disc; 75. turning pipe; 751. feeding end; 76. diversion hole; 77. discharge hole. DETAILED DESCRIPTION

[0018] The following will be described clearly and completely in conjunction with the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0019] Embodiment, this embodiment provides a tablet granulation drying device, such as Figure 1 As shown, it includes a drying cylinder 1, the upper end of the drying cylinder 1 is a feeding opening structure, and the bottom end gradually narrows into a truncated cone-shaped closed structure. The drying cylinder 1 is used as a place for drying tablet particles.

[0020] The material turning part includes a supporting rod 7, a material distribution box 72, a material collecting pipe 74 and a plurality of material turning pipes 75 arranged radially along the material collecting pipe 74. The supporting rod 7 is rotatably mounted on the inner bottom wall of the truncated cone-shaped closed structure, such as Figure 2 As shown, a base 5 is fixed to the bottom wall of the truncated cone type closed structure, and a motor is installed in the base 5. The output end of the motor rotates through the bottom wall of the truncated cone type closed structure and is fixedly connected to the bottom wall of the supporting upright 7. The motor provides power for the rotation of the supporting upright 7. An enlarged end 71 is provided at the top of the supporting upright 7, and a through hole is radially provided at the enlarged end 71, one end of the distributing box 72 passes through the through hole horizontally and is rotatably connected to the inner side walls of the through hole, a collecting pipe 74 is rotatably arranged at one end of the distributing box 72, an annular rack 12 is provided on the radial inner wall near the bottom of the drying cylinder 1, a toothed disc 741 is fixed to the end of the collecting pipe 74, and the toothed disc 741 is meshed with the annular rack 12; the rotation of the supporting upright 7 can drive the distributing box 72 and the collecting pipe 74 to rotate and adjust around the supporting upright 7, and at the same time drive the toothed disc 741 to roll along the annular rack 12, so that the collecting pipe 74 together with a plurality of turning pipes 75 rotate around the axis of the collecting pipe 74, and in this process, the turning pipe 75 can be used to turn the tablet particles stacked together up and down.

[0021] At the same time, a continuously connected corrugated structure is provided on the upper end surface of the annular rack 12, and the toothed disc 741 rolls in real time along the surface wall of the corrugated structure of the annular rack 12. When the material distribution box 72 is rotated and adjusted with the rotation position of the inner wall of the through hole as the center, the toothed disc 741 rolls along the corrugated structure of the annular rack 12, which will lift and drop one end of the material distribution box 72 located on the toothed disc 741 upward, alternately, and the two ends of the material distribution box 72 swing up and down alternately.

[0022] It should be noted that there is a gap between the end of the distribution box 72 away from the collecting pipe 74 and the annular rack 12. In this way, when the end of the distribution box 72 away from the collecting pipe 74 descends, it will not touch the annular rack 12, and will not affect the up and down swinging adjustment of the toothed disc 741 of the distribution box 72.

[0023] In order to make the toothed disc 741 at the end of the collecting pipe 74 contact and mesh with the annular rack 12, two spring pieces 73 are symmetrically arranged on the radial outer wall of the enlarged end 71 and located on the upper sides of the two openings of the through hole. The ends of the spring pieces 73 are against the upper end surface of the material distribution box 72. Figure 2 As shown, the elastic force of the spring sheet 73 (stainless steel spring sheet) is used to press down on both sides of the rotating position of the material distribution box 72 to ensure that it maintains a relatively horizontal state without external force. Ensure that the toothed disc 741 can mesh with the annular rack 12 in real time, thereby ensuring that the material turning tube 75 can rotate and turn the material.

[0024] The specific turning process is as follows: after tens of thousands of tablet particles are thrown into the drying cylinder 1, they are concentrated and piled at the truncated cone-shaped closed structure. Then, the support upright rod 7 can rotate under the drive of the motor, driving the toothed disc 741 to roll along the upper end of the annular rack 12, thereby driving the turning tube 75 to make a circular motion with the collecting tube 74 as the rotation center, and the material distribution box 72 rotates in the plane where it is located, and the toothed disc 741 rolls along the annular rack 12. The toothed disc 741 rolls along the corrugated structure of the annular rack 12, which will lift and drop one end of the material distribution box 72 located at the toothed disc 741 upward, alternately, and the two ends of the material distribution box 72 swing up and down alternately, so that it can swing up and down around the rotation position in the through hole. The turning depth of the turning tube 75 is different, so the turning depth of the tablet particles piled together is different, which can change the position of the tablet particles to the maximum extent.

[0025] At the same time, if Figure 2 and Figure 7 As shown, a hot air blower 6 is also installed in the base 5, and the air outlet of the hot air blower 6 is connected to a conduit, and the end of the conduit is fixedly connected to a hollow air storage box 61, and the air storage box 61 is rotatably sleeved on the outer wall of the bottom end of the support pole 7. A baffle located on the upper and lower surfaces of the air storage box 61 is arranged on the outer wall of the support pole 7, which does not affect the rotation of the support pole 7 relative to the air storage box 61 on the one hand, and does not cause the air storage box 61 to fall on the other hand. A connecting hole is provided on the inner wall of the air storage box 61, and an air guide channel is axially provided on the support pole 7. The top opening of the air guide channel extends to the bottom wall of the through hole and is located below the material distribution box 72. An anti-blocking net is provided at the top opening of the air guide channel, and the bottom opening of the air guide channel is connected to the connecting hole. The air outlet temperature of the hot air blower 6 is preset, and the hot air is guided into the air storage box 61 through the conduit, and blown into the air guide channel of the support pole 7 through the hole, so that the hot air enters the drying cylinder 1 through the anti-blocking net for thermal drying.

[0026] In this embodiment, further, Figure 3 , Figure 4 and Figure 5As shown, in order to further improve the turning range of the tablet particles piled together, a hollow structure is provided in the axial direction of the collecting pipe 74, and the end away from the material distribution box 72 is a closed structure. The radial side wall of the collecting pipe 74 is provided with an inlet connected to the turning pipe 75, and the material distribution box 72 is provided with a discharge hole 77 connected to the hollow structure. The hollow structure, the inlet and the discharge hole 77 constitute a material guide channel. For example, the collecting pipe 74 is arranged along the Figure 5 The material turning tube 75 turns synchronously with the material turning tube 75. A scooping plate is provided at the end of the material turning tube 75. When the material turning tube 75 turns over, the scooping plate can be tilted and embedded in the tablet particles in the deep layer. As the material turning tube 75 continues to turn over, the tablet particles can be scooped up and enter the material turning tube 75. When the opening of the material turning tube 75 is tilted upward, the tablet particles entering the material turning tube 75 will enter the collecting tube 74 through the entrance. Since the end of the collecting tube 74 away from the distributing box 72 is a closed structure, the toothed disc 741 rolls along the corrugated structure of the annular rack 12, which will lift and drop the end of the distributing box 72 located at the toothed disc 741 upward and alternately. The two ends of the distributing box 72 swing up and down alternately, and the tablet particles will slide along the hollow structure to the discharge hole 77 of the distributing box 72 and be discharged from the opening of the discharge hole 77, thereby changing the position of the tablet particles over a large range and accelerating the drying speed.

[0027] Furthermore, a plurality of flow dividing holes 76 are provided on both side walls of the material dividing box 72, and an expansion portion is provided at the connection between the flow dividing hole 76 and the material discharging hole 77, such as Figure 4 As shown, because the material distribution box 72 is continuously rotating, the tablet particles entering the discharge hole 77 will also be thrown out from the opening of the diverter hole 76, further expanding the range of variation.

[0028] In order to prevent the tablet particles entering the hollow structure from being discharged from the opposite turning tube 75, the two opposite turning tubes 75 symmetrically distributed have an entry end extending through the feed port into the hollow structure at one end close to each other, and the two feed ends 751 are staggered. Figure 6 As shown, under the premise of not affecting the introduction of tablet particles into the hollow structure, the staggered distribution of the two feed ends 751 can avoid one feed end 751 being introduced and the other feed end 751 being exported.

[0029] This embodiment also includes a separator, such as Figure 1 , Figure 8 , Fig. 9 and Fig.10As shown, the partition includes a partition sleeve 2 and a plurality of partitions 22. An annular extension ring is radially extended at the upper end of the partition sleeve 2. The plurality of partitions 22 are arranged in an annular structure on the radial outer wall of the partition sleeve 2, and the top wall of the partition 2 is connected to the bottom wall of the annular extension ring. The edge of the partition sleeve 2 is provided with a second ventilation hole directly opposite to the space between two adjacent partitions 22. An annular base 11 is fixed on the inner wall of the drying cylinder 1. The plurality of partitions 22 are seated on the upper end surface of the annular base 11, and the partitions 22 are fitted with the inner wall of the drying cylinder 1 to form a plurality of independent chambers. The annular base 11 is provided with a ventilation hole 3 connected with the chamber; an annular thread ring 21 is fixed on the upper end surface of the partition sleeve 2, and the annular thread ring 21 is threadedly connected with the wind shield 3. During the drying process, the plurality of partitions 22 of the partition are inserted into the drying cylinder 1 and seated on the annular base 11. The connecting hole 3 and the ventilation hole 2 corresponding to each chamber form independent ventilation channels. The advantage of this is that the hot air blown by the hot air blower 6 enters the drying cylinder 1, enters the chamber from the multiple ventilation holes 3 of the annular base 11, and then enters the drying cylinder 1 again from the ventilation hole 2, forming a position at the upper part of the drying cylinder 1. Hot air is blown out at multiple points to form an upper heat wave, which has the effect of baking the tablet particles located in the lower layer of the drying cylinder 1, rather than directly blowing hot air, to avoid excessive drying and cracking.

[0030] In addition, if Figure 8 and Fig. 9 As shown, a high-pressure fan 4 is fixed to the top wall of the wind shield 3, and the air inlet of the high-pressure fan 4 extends to the outside of the top of the wind shield 3. The high-pressure fan 4 is added to provide a higher wind force in the drying cylinder 1, thereby accelerating the flow rate of heat in the drying cylinder 1. At the same time, in order to avoid excessive pressure in the drying cylinder 1, a plurality of ventilation holes 1 and a connecting hole 1 are provided on the annular extension ring for pressure relief.

[0031] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A tablet granulation drying device, characterized in that: include: A drying cylinder (1), wherein the upper end of the drying cylinder (1) is a feeding opening structure, and the lower end gradually narrows to a truncated cone-shaped closed structure; A material turning component, the material turning component comprising a supporting upright rod (7), a material distribution box (72), a material collection pipe (74) and a plurality of material turning pipes (75) radially arranged along the material collection pipe (74); the supporting upright rod (7) is rotatably mounted on the inner bottom wall of the truncated cone-shaped closed structure; the top of the supporting upright rod (7) is provided with an enlarged end (71), and the enlarged end (71) is radially provided with a through hole; one end of the material distribution box (72) passes through the through hole horizontally and is rotatably connected to the inner side walls of the through hole; the material collection pipe (74) is rotatably arranged at one end of the material distribution box (72); an annular rack (12) is provided on the radial inner wall near the bottom of the drying cylinder (1); a toothed disc (741) is fixed to the end of the material collection pipe (74), and the toothed disc (741) is meshed with the annular rack (12); The upper end surface of the annular rack (12) is provided with a continuously connected corrugated structure, and the toothed disc (741) is in real-time rolling contact along the surface wall of the corrugated structure of the annular rack (12); The material turning component can be rotated and adjusted to drive the toothed disc (741) to roll along the upper end of the annular rack (12), thereby driving the material turning tube (75) to make an annular motion with the collecting tube (74) as the rotation center. While the material distribution box (72) rotates within the plane in which it is located, it can also swing up and down around the rotation position in the through hole, thereby adjusting the turning depth of the material turning tube (75) and changing the position of the tablet particles.

2. The tablet granulation drying device according to claim 1, characterized in that: There is a gap between one end of the material distribution box (72) away from the material collecting pipe (74) and the annular rack (12).

3. The tablet granulation drying device according to claim 1, characterized in that: The radial outer wall of the enlarged end (71) is symmetrically provided with two spring sheets (73) located on the upper sides of the two openings of the through hole, and the ends of the spring sheets (73) abut against the upper end surface of the material distribution box (72).

4. The tablet granulation drying device according to claim 1, characterized in that: A base (5) is fixed to the bottom wall of the truncated cone-shaped closed structure, a motor is installed in the base (5), and the output end of the motor rotates through the bottom wall of the truncated cone-shaped closed structure and is fixedly connected to the bottom wall of the supporting upright pole (7).

5. The tablet granulation drying device according to claim 4, characterized in that: A hot air blower (6) is also installed in the base (5), the air outlet of the hot air blower (6) is connected to a duct, the end of the duct is fixedly connected to an air storage box (61) with a hollow structure, the air storage box (61) is rotatably sleeved on the outer wall of the bottom end of the support upright (7), the inner side wall of the air storage box (61) is provided with a connecting hole, the support upright (7) is axially provided with an air guide channel, the top opening of the air guide channel extends to the bottom wall of the through hole and is located below the material distribution box (72), the top opening of the air guide channel is provided with an anti-blocking net, and the bottom opening of the air guide channel is connected to the connecting hole.

6. The tablet granulation and drying device according to claim 1, characterized in that: The collecting pipe (74) is provided with a hollow structure in the axial direction, and one end away from the material distribution box (72) is a closed structure. The radial side wall of the collecting pipe (74) is provided with an inlet connected to the material turning pipe (75). The material distribution box (72) is provided with a discharge hole (77) connected to the hollow structure. The hollow structure, the inlet and the discharge hole (77) constitute a material guiding channel.

7. The tablet granulation and drying device according to claim 6, characterized in that: The side walls of the material distribution box (72) are each provided with a plurality of flow distribution holes (76), and an enlarged portion is provided at the connection between the flow distribution holes (76) and the material discharge hole (77).

8. The tablet granulation and drying device according to claim 6, characterized in that: Two symmetrically distributed opposite material turning tubes (75) are close to each other and each has an entry end extending through the feed opening and entering the hollow structure, and the two feed ends (751) are staggered.

9. The tablet granulation and drying device according to any one of claims 1 to 8, characterized in that: The drying cylinder (1) further comprises a separator, the separator comprising a separator sleeve (2) and a plurality of separators (22), the upper end of the separator sleeve (2) being provided with an annular extension ring extending radially, the plurality of separators (22) being arranged in an annular structure on the radial outer wall of the separator sleeve (2), the top wall of the separator (22) being connected to the bottom wall of the annular extension ring, the annular extension ring being provided with a plurality of ventilation holes 1, the edge of the separator sleeve (2) being provided with ventilation holes 2 facing the space between two adjacent separators (22), the inner wall of the drying cylinder (1) being fixed with an annular base (11), the plurality of separators (22) being seated on the upper end surface of the annular base (11), the separators (22) being fitted with the inner wall of the drying cylinder (1) to form a plurality of independent chambers, the annular base (11) being provided with ventilation holes 3 communicating with the chambers; An annular threaded ring (21) is fixed to the upper end surface of the separation sleeve (2), and the annular threaded ring (21) is threadedly connected to a wind shield (3).

10. The tablet granulation and drying device according to claim 9, characterized in that: A high-pressure fan (4) is fixed to the inner top wall of the wind shield (3), and an air inlet of the high-pressure fan (4) extends to the outside of the top end of the wind shield (3).

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