Compact slide automatic scanning device

Abstract

The invention provides a compact automatic slide scanning device which comprises an electronic scanning microscope, the electronic scanning microscope comprises a liftable lifting platform, the lifting platform is provided with a two-dimensional displacement platform, the two-dimensional displacement platform comprises a connecting bottom plate, and the connecting bottom plate is used for being connected with the lifting platform of the electronic scanning microscope. The upper end of the electronic scanning microscope is provided with a movable bearing table, the bearing table is provided with a movable film clip tray in the length direction, the film clip tray is used for placing a film clip body, the film clip tray is perpendicular to the moving direction of the bearing table, one end of the bearing table is provided with a film clip storage frame capable of moving up and down, and the film clip storage frame is of a frame-shaped structure with two through ends. The through end of the slide holder storage rack faces the length direction of the bearing table, the slide holder storage rack is provided with a plurality of slide holder slots for storing slide holder main bodies along the height direction, and a downward preview camera is arranged above one end, close to the slide holder storage rack, of the bearing table, so that the problems of miniaturization and light weight of the slide scanner are solved.

Description

Technical Field

[0001] The invention relates to the field of glass slide scanning, and in particular to a compact glass slide automatic scanning device. Background Art

[0002] When testing cells and tissues, a slide scanner is usually required. The slide scanner is equipped with an electron microscope. After the cells and tissues are prepared, the slide is inserted into the microscope objective for observation and scanning. Existing slide scanners usually use a slide holder to carry multiple slides and insert them into the instrument for testing, reducing the workload of loading and unloading slides. Slide scanners are usually equipped with a two-dimensional moving stage, which, combined with the lifting function of the microscope stage, can realize multi-area image scanning.

[0003] In order to further reduce the number of manual slide loading, an automatic slide loading mechanism is usually installed on one side of the slide scanner. Through the external mechanical arm structure, the mechanical arm grabs the slide holder and moves back and forth between the slide tower and the scanner's support table. Since the mechanical arm is expensive and requires an additional transverse movement mechanism, the overall cost of the scanner will be greatly increased. In addition, the mechanical arm and transverse movement mechanism require additional space, which is not conducive to the miniaturization of the equipment. Summary of the invention

[0004] The invention provides a compact automatic glass slide scanning device, which solves the problem of miniaturization and lightness of the glass slide scanner.

[0005] To solve the above technical problems, the technical solution adopted by the present invention is: a compact automatic glass slide scanning device, including an electronic scanning microscope, the electronic scanning microscope includes a liftable lifting platform, a backlight is provided in the center of the lifting platform, a two-dimensional displacement platform is provided on the lifting platform, the two-dimensional displacement platform includes a connecting base plate, the connecting base plate is used to connect with the lifting platform of the electronic scanning microscope, a movable carrying platform is provided at the upper end of the electronic scanning microscope, a movable film clamp tray is provided on the carrying platform along the length direction, the film clamp tray is used to place the film clamp body, the moving directions of the film clamp tray and the carrying platform are perpendicular, a film clamp storage rack that can move up and down is provided at one end of the carrying platform, the film clamp storage rack is a frame structure with two ends through, the through end of the film clamp storage rack is facing the length direction of the carrying platform, a plurality of film clamp slots for storing the film clamp body are provided on the film clamp storage rack along the height direction, and a downward preview camera is provided above one end of the carrying platform close to the film clamp storage rack.

[0006] In a preferred embodiment, a hollow slot is provided at one end of the supporting platform, a control board is provided in the hollow slot, a first photoelectric proximity sensor and a second photoelectric proximity sensor are provided on the control board, the first photoelectric proximity sensor is used to detect the origin position of the film clip tray, and the second photoelectric proximity sensor is used to detect the origin position of the supporting platform.

[0007] In the preferred scheme, a first guide rail and a first lead screw are provided on the supporting platform, the film clamp tray is slidably connected to the first guide rail through a slider, a first nut seat is mounted on the first lead screw, one end of the film clamp tray is connected to the first nut seat, a first servo motor is provided on the supporting platform, and the shaft end of the first servo motor is connected to the end of the first lead screw.

[0008] In the preferred scheme, a third guide rail is provided at the lower end of the support platform, and the connecting base plate is slidably connected to the third guide rail through a slider, a third servo motor is provided at the lower end of the support platform, a third lead screw is connected to the shaft end of the third servo motor, a third lead screw is sleeved with a third nut seat, and the third nut seat is connected to the connecting base plate.

[0009] In the preferred solution, a plurality of conductive columns are provided on the control board, transition blocks are provided at the ends of the first photoelectric proximity sensor and the second photoelectric proximity sensor, the output ends of the first photoelectric proximity sensor and the second photoelectric proximity sensor are electrically connected to each conductive sleeve, the transition block is provided with a plurality of conductive sleeves, each conductive sleeve is sleeved with each conductive column, a mounting ear is provided on one side of the transition block, a threaded sleeve is embedded in the control board, and a screw passes through the mounting ear to be threadedly connected with the threaded sleeve.

[0010] In a preferred embodiment, stop ridges are provided on both side ends of the film clip slot, a third magnet is provided on the stop ridges, a plurality of first magnets and a plurality of second magnets are provided at the bottom of the film clip body, a plurality of fourth magnets are provided on the film clip tray, each third magnet is used to attract each second magnet, and each fourth magnet is used to attract each second magnet.

[0011] In the preferred solution, a vertical extension arm is provided at one end of the support platform close to the film clip storage rack, a second guide rail is provided on the extension arm, a slider is provided on one side of the film clip storage rack and is slidably connected to the second guide rail, a jumper plate is also provided on the side of the film clip storage rack, a second screw is sleeved with a second nut seat, the end of the jumper plate is connected to the second nut seat, a second servo motor is provided on the support platform, and the shaft end of the second servo motor is connected to the end of the second screw.

[0012] In a preferred embodiment, the slide clamp body is provided with a plurality of glass slide grooves arranged side by side, each glass slide groove is provided with a first hollow hole in the center, each glass slide groove is provided with a tail pressure plate at one end, the tail pressure plate includes a deformable front extension arm, a second buckle portion is provided at the end of the front extension arm, and a first buckle portion is provided at the other end of the glass slide groove, and the first buckle portion and the second buckle portion clamp the two ends of the glass slide.

[0013] The first buckle portion is provided with a first inverted cone surface, and the second buckle portion is provided with a second inverted cone surface. The first inverted cone surface and the second inverted cone surface are respectively abutted against two ends of the glass slide.

[0014] The tail pressing piece is provided with two front extending arms arranged at an angle, and the second buckle parts of the two front extending arms are against two corner positions of one end of the glass slide.

[0015] In the preferred solution, the camera support frame is a door-shaped structure, and connecting plates are provided at both ends of the camera support frame. The connecting plates are provided with a front plug rod and a rear plug rod. Front plug holes are provided at both ends of the film clamp tray. The front plug rod is slidably plugged into the front plug hole. Connecting base blocks are provided at both ends of the support platform. The connecting base blocks are provided with a rear plug hole. The rear plug rod is slidably plugged into the rear plug hole. An annular groove is provided at the end of the front plug rod, and a spring top plug is provided at the film clamp tray. One end of the spring top plug rests in the annular groove, and a stop plate is provided at the end of the rear plug rod. The rear plug rod is sleeved with a first spring, and one end of the first spring rests on the stop plate.

[0016] In the preferred embodiment, a ball is provided in the spring top plug, and the ball is used to abut against the annular groove. A slidable ball abutment block is provided on one side of the ball. A threaded rear adjustment block is also provided in the spring top plug, and a second spring is provided between the rear adjustment block and the ball abutment block.

[0017] The beneficial effects of the present invention are as follows: the film clip tray of the scanner itself is used as a transfer mechanism to take and place the film clip without the need for an additional mechanical arm structure, the cost is low, and the structure is compact and small; since the scanner is not in a working state during the film taking and placing process, the film feeding mechanism does not occupy the scanning cycle time; the film clip storage rack adopts a frame structure with hollowed-out opposite sides, one of the hollowed-out sides is directly opposite to the scanning area, and the film feeding route of the film clip tray is a straight line, which is the shortest distance compared to other types of film feeding mechanisms, so the film feeding efficiency is high; the control board is directly installed at one end of the carrier table, without the need for a separate control box space, and the control board is used as an installation substrate to install a position sensor, so that the film clip moving module structure is compact, which is conducive to the miniaturization of the glass slide scanner; the control board is close to the motor of the linear moving mechanism, the cable requirement is short, the space requirement for wire troughs, drag chains, etc. is small, and the cost is lower; the preview camera adopts a follow-up structure, which can keep relatively still with the film clip for a short time when the film clip passes under the camera, thereby improving the quality of the preview image without increasing the cycle time. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0019] Figure 1 It is a schematic diagram of the present invention.

[0020] Figure 2 This is the schematic diagram of the scanning mirror lifting mechanism.

[0021] Figure 3 It is a schematic diagram of the upper part of the translation stage mechanism.

[0022] Figure 4 It is a schematic diagram of the bottom of the translation stage mechanism.

[0023] Figure 5 It is a schematic diagram of the film feeding mechanism.

[0024] Figure 6It is a schematic diagram of the other side of the film feeding mechanism.

[0025] Figure 7 This is an enlarged view of the film clip slot.

[0026] Figure 8 It is a schematic diagram of the upper side of the film holder.

[0027] Fig. 9 This is a cross-sectional view of the slide trough after loading the slide.

[0028] Fig.10 It is a schematic diagram of the bottom side of the film holder.

[0029] Fig.11 It is a schematic diagram of a film clip storage rack for film clip applications.

[0030] Fig.12 This is a diagram of the tray structure for film clamp applications.

[0031] Fig.13 This is an enlarged view of the first detected block.

[0032] Fig.14 This is an enlarged view of the second detected block.

[0033] Fig.15 It is a cross-sectional view of the fixed structure of the photoelectric proximity sensor.

[0034] Fig.16 It is a cross-sectional diagram of the electrical connection structure of a photoelectric proximity sensor.

[0035] Fig.17 This is an enlarged diagram of the electrical connection structure of the photoelectric proximity sensor.

[0036] Fig.18 This is a partial picture of the camera support.

[0037] Fig.19 This is a diagram of the camera support frame follow-up structure.

[0038] Fig. 20 It is a cross-sectional view of the spring top plug.

[0039] In the figure: the film clip body 1; the glass slide groove 101; the first buckle part 102; the first hollow hole 103; the second hollow hole 104; the first inverted cone 105; the outer lug 106; the groove part 107; the first magnet 108; the second magnet 109; the tail pressure plate 2; the front extension arm 201; the second buckle part 202; the second inverted cone 203; the film clip storage rack 3; the film clip slot 301; the third magnet 302; the stop edge 303; the film clip tray 4; the fourth magnet 401; the support platform 5; the extension arm 501; the first Guide rail 502; first servo motor 503; first lead screw 504; first nut seat 505; hollow portion 506; second guide rail 507; second lead screw 508; second nut seat 509; jumper plate 510; second servo motor 511; control board 6; first photoelectric proximity sensor 601; second photoelectric proximity sensor 602; first detected block 603; first waist-shaped hole 604; second detected block 605; second waist-shaped hole 606; raised portion 607; strip groove 608; transition block 60 9; mounting ear 610; threaded sleeve 611; conductive column 612; outlet terminal 613; conductive sleeve 614; contact piece 615; wiring hole 616; connecting bottom plate 7; first through hole portion 701; third servo motor 702; third lead screw 703; third screw nut seat 704; third guide rail 705; lifting platform 8; fourth lead screw 801; guide rod 802; fourth screw nut seat 803; second through hole portion 804; sliding sleeve 805; bevel gear transmission group 806; fourth servo motor 807; camera support Frame 9; connecting plate 901; front plug rod 902; plug-in base block 903; rear plug rod 904; front plug hole 905; rear plug hole 906; annular groove 907; stopper 908; first spring 909; backlight 10; electron scanning microscope 11; lens 1101; hollow seam 12; preview camera 13; fill light 1301; baffle 14; opening 1401; spring top plug 15; ball 1501; ball abutment block 1502; second spring 1503; rear adjustment block 1504.Film clip body 1; slide slot 101; first buckle portion 102; first hollow hole 103; second hollow hole 104; first inverted cone 105; outer lug 106; groove portion 107; first magnet 108; second magnet 109; tail pressure plate 2; front extension arm 201; second buckle portion 202; second inverted cone 203; film clip storage rack 3; film clip slot 301; third magnet 302; stop edge 303; film clip tray 4; fourth magnet 401; support platform 5; extension arm 501; first guide rail 502; first servo motor 503; first lead screw 504; first nut seat 505; hollow portion 506; second guide rail 507; second lead screw 508; second nut seat 509; jumper plate 510; second servo motor 511; control board 6; first photoelectric proximity sensor 601; second photoelectric proximity sensor 602 ; The first detected block 603; The first waist-shaped hole 604; The second detected block 605; The second waist-shaped hole 606; The raised portion 607; The strip groove 608; The transition block 609; The mounting ear 610; The threaded sleeve 611; The conductive column 612; The outlet terminal 613; The conductive sleeve 614; The contact piece 615; The wiring hole 616; The connecting bottom plate 7; The first through hole portion 701; The third servo motor 702; The third lead screw 703; The third nut seat 704; The third guide rail 705; The lifting platform 8; The fourth lead screw 801; The guide rod 802; The fourth nut seat 803; The second through hole portion 804; The sliding sleeve 805; The bevel gear transmission group 806; The fourth servo motor 807; The camera support frame 9; The backlight 10; The electronic scanning microscope 11; The lens 1101; The hollow seam 12; The preview camera 13; The baffle 14; The opening portion 1401. DETAILED DESCRIPTION

[0040] like Figure 1-20 In the invention, a compact automatic slide scanning device is provided, comprising an electronic scanning microscope 11, wherein the electronic scanning microscope 11 comprises a liftable lifting platform 8, wherein a backlight 10 is arranged in the center of the lifting platform 8, wherein a two-dimensional displacement platform is arranged on the lifting platform 8, wherein the two-dimensional displacement platform comprises a connecting base plate 7, wherein the connecting base plate 7 is used to connect with the lifting platform 8 of the electronic scanning microscope 11, wherein a movable supporting platform 5 is arranged at the upper end of the electronic scanning microscope 11, wherein a movable film clamp tray 4 is arranged along the length direction of the supporting platform 5, wherein the film clamp tray 4 is used to place a film clamp body 1, wherein the moving directions of the film clamp tray 4 and the supporting platform 5 are perpendicular, wherein a film clamp storage rack 3 which can move up and down is arranged at one end of the supporting platform 5, wherein the film clamp storage rack 3 is a frame-type structure with two ends through, wherein the through end of the film clamp storage rack 3 faces the length direction of the supporting platform 5, wherein a plurality of film clamp slots 301 for storing the film clamp body 1 are arranged along the height direction, wherein a downward-facing preview camera 13 is arranged above one end of the supporting platform 5 close to the film clamp storage rack 3.

[0041] A vertical baffle 14 is provided between the carrier platform 5 and the film clip storage rack 3. The baffle 14 is provided with an opening 1401 near the carrier platform 5. The preview camera 13 is provided at one side of the opening 1401 near the carrier platform 5 and connected to the carrier platform 5 through the camera support frame 9. The lower end of the baffle 14 is fixed to the extension arm 501 through a connecting column. The opening 1401 serves as a passage so that the film clip tray 4 can move back and forth between the film clip slot 301 and the carrier platform 5.

[0042] The film clip tray 4 is used to reciprocate above the film clip slot 301 and the hollow portion 506 on the carrier 5 to transport the film clip body 1.

[0043] The electron scanning microscope 11 includes a fourth vertical lead screw 801 and a guide rod 802. The fourth lead screw 801 is sleeved with a fourth screw nut 803. One end of the fourth screw nut 803 is provided with a sliding sleeve 805. The sliding sleeve 805 is slidably sleeved with the guide rod 802. The bottom end of the fourth lead screw 801 is provided with a bevel gear transmission group 806. The base of the electron scanning microscope 11 is provided with a fourth servo motor 807. The fourth servo motor 807 drives the fourth lead screw 801 to rotate through the bevel gear transmission group 806. One end of the lifting platform 8 is connected to the fourth screw nut 803, and the fourth lead screw 801 rotates to move the lifting platform 8 up and down.

[0044] The connecting bottom plate 7, the supporting platform 5 and the film holder tray 4 are all provided with hollow structures in the center. The lifting platform 8 is provided with a second through hole portion 804 in the center, the connecting bottom plate 7 is provided with a first through hole portion 701 in the center, and the supporting platform 5 is provided with a hollow portion 506 in the center, which is the observation area of ​​the lens 1101 of the electron scanning microscope 11. The center of the film holder body 1 is also provided with a hole structure that allows light to pass through. The lifting platform 8 is installed at the lower end of the lifting platform 8. The lifting platform 8 is arranged at the second through hole portion 804, and the backlight 10 faces the lower end surface of the film holder body 1. The hollow structure is to enable the backlight source at the bottom of the microscope to illuminate the bottom surface of the glass slide. A lens assembly is disposed above the electron scanning microscope 11 , and the objective lens faces the upper end surface of the film holder body 1 .

[0045] In the preferred scheme, a hollow slot 12 is provided at one end of the supporting platform 5, and a control board 6 is provided in the hollow slot 12. The control board 6 is provided with a first photoelectric proximity sensor 601 and a second photoelectric proximity sensor 602. The first photoelectric proximity sensor 601 is used to detect the origin position of the film clamp tray 4, and the second photoelectric proximity sensor 602 is used to detect the origin position of the supporting platform 5.

[0046] The electrical contacts of the first photoelectric proximity sensor 601 and the second photoelectric proximity sensor 602 can be directly welded to the electrical contacts on the circuit board without the need for additional wiring. This direct connection method reduces wiring space and improves the compactness of the device.

[0047] In the preferred embodiment, a first guide rail 502 and a first lead screw 504 are provided on the supporting platform 5, the film clamp tray 4 is slidably connected to the first guide rail 502 through a slider, a first nut seat 505 is sleeved on the first lead screw 504, one end of the film clamp tray 4 is connected to the first nut seat 505, and a first servo motor 503 is provided on the supporting platform 5, and the shaft end of the first servo motor 503 is connected to the end of the first lead screw 504.

[0048] Two parallel first guide rails 502 can be installed on the support platform 5, and both ends of the film holder tray 4 are connected to the first guide rails 502 through sliders.

[0049] A strip groove 608 is provided on one side of the film holder tray 4 close to the control board 6 , a first detected block 603 is provided in the strip groove 608 , a first waist-shaped hole 604 is provided on the first detected block 603 , and a screw passes through the first waist-shaped hole 604 to be threadedly connected with the bottom end of the strip groove 608 .

[0050] In the preferred scheme, a third guide rail 705 is provided at the lower end of the supporting platform 5, and the connecting base plate 7 is slidably connected to the third guide rail 705 through a slider, and a third servo motor 702 is provided at the lower end of the supporting platform 5. The shaft end of the third servo motor 702 is connected to a third lead screw 703, and the third lead screw 703 is sleeved with a third nut seat 704, and the third nut seat 704 is connected to the connecting base plate 7.

[0051] A protrusion 607 is provided on one side of the third nut seat 704 , a second detected block 605 is provided on the protrusion 607 , and a second waist-shaped hole 606 is provided on the second detected block 605 . A screw passes through the second waist-shaped hole 606 to be threadedly connected with the protrusion 607 .

[0052] The first servo motor 503 and the third servo motor 702 use servo motors, and the displacement distance can be inferred by the number of pulses. Therefore, for a unidirectional moving component, as long as the origin position is determined, the specific position of the moving component at a certain moment can be calculated, which has low cost and reliable control.

[0053] After the slide is loaded into the slot on the slide holder body 1, the slide holder body 1 is placed on the slide holder tray 4 for positioning, the third servo motor 702 drives the carrier 5 to move relative to the connecting bottom plate 7, and the first servo motor 503 drives the slide holder tray 4 to move along the length direction of the carrier 5. The objective lens of the electron scanning microscope 11 is fixed, so the slide holder body 1 on the slide holder tray 4 can move to a set position in the horizontal direction relative to the objective lens. Then the fourth servo motor 807 starts to drive the lifting platform 8 to move up and down to adjust the focal length.

[0054] Since the first detected block 603 and the second detected block 605 are installed by using waist-shaped holes, they can be extended and retracted along the length direction to adjust the origin position of the single-axis moving component.

[0055] In the preferred embodiment, a plurality of conductive posts 612 are provided on the control board 6, and transition blocks 609 are provided at the ends of the first photoelectric proximity sensor 601 and the second photoelectric proximity sensor 602. The outlet ends 613 of the first photoelectric proximity sensor 601 and the second photoelectric proximity sensor 602 are electrically connected to each conductive sleeve 614. The transition block 609 is provided with a plurality of conductive sleeves 614, and each conductive sleeve 614 is sleeved with each conductive post 612. A mounting ear 610 is provided on one side of the transition block 609, and a threaded sleeve 611 is embedded in the control board 6, and a screw passes through the mounting ear 610 to be threadedly connected with the threaded sleeve 611.

[0056] The transition block 609 can be customized according to the specific specifications of the photoelectric sensor and fixed to the end of the photoelectric sensor by bonding or welding.

[0057] The number of the conductive pillars 612 and the conductive sleeves 614 should be at least three. A wiring hole 616 is provided in the transition block 609. The power line and the signal line of the outlet terminal 613 are routed through the wiring hole 616 to the outer wall of the conductive sleeve 614 and welded thereto.

[0058] The conductive column 612 is welded to the conductive contact on the control board 6, protruding from the control board 6, and can be used for conduction and positioning. The inner wall of the conductive sleeve 614 is provided with an elastic contact sheet 615, which can be made of copper or aluminum. An annular groove is provided at the end of the conductive column 612. One end of the contact sheet 615 is connected to the inner wall of the conductive sleeve 614, and the other end rests in the annular groove.

[0059] Compared with directly welding the first photoelectric proximity sensor 601 and the second photoelectric proximity sensor 602 to the control board 6, this plug-in positioning and screw fixing method facilitates the replacement of the sensors and avoids replacing the entire circuit board.

[0060] In the preferred embodiment, stop ridges 303 are provided on both side ends of the film clip slot 301, and third magnets 302 are provided on the stop ridges 303. A plurality of first magnets 108 and a plurality of second magnets 109 are provided at the bottom of the film clip body 1, and a plurality of fourth magnets 401 are provided on the film clip tray 4. Each third magnet 302 is used to attract each second magnet 109, and each fourth magnet 401 is used to attract each second magnet 109.

[0061] After the tissue or cell slide is prepared, the slide is inserted into the slide holder body 1 and stored in the slide holder slot 301. When the slide needs to be scanned, the slide holder tray 4 is horizontally moved from the open end of the slide holder storage rack 3 close to the carrier 5 to the slide holder slot 301. At this time, the slide holder storage rack 3 moves slightly downward as a whole, so that the upper end surface of the slide holder tray 4 contacts the bottom of the slide holder body 1, and at this time, the second magnet 109 attracts the fourth magnet 401 to complete the positioning of the slide holder body 1 on the slide holder tray 4. Subsequently, the slide holder tray 4 moves in the opposite direction, takes a preview photo when passing under the preview camera 13, and then moves to the top of the hollow portion 506, which is the observation area of ​​the microscope.

[0062] When the electron scanning microscope finishes scanning the slide, the slide holder tray 4 returns the slide holder body 1 to the original slide holder slot 301. At this time, the slide holder storage rack 3 moves, and the stop ridges 303 on both sides of the slide holder slot 301 support the bottom of the slide holder body 1. The second magnet 109 is aligned with the third magnet 302. The stop ridges 303 lift the slide holder body 1 to break the attraction of the fourth magnet 401, so that the slide holder body 1 is separated from the slide holder tray 4, and the slide holder body 1 is positioned in the slide holder slot 301. Subsequently, the slide holder tray 4 retracts to the center of the carrier 5, and the slide holder storage rack 3 moves upward or downward to make the next adjacent slide holder slot 301 located at the slide taking station, and the cycle continues until all slides on the slide holder body 1 are scanned and the staff removes all the slide holder bodies 1.

[0063] In the preferred embodiment, a vertical extension arm 501 is provided at one end of the supporting platform 5 close to the film clip storage rack 3, a second guide rail 507 is provided on the extension arm 501, a slider is provided on one side of the film clip storage rack 3 and is slidably connected to the second guide rail 507, a jumper plate 510 is also provided on the side of the film clip storage rack 3, a second screw 508 is sleeved with a second nut seat 509, an end of the jumper plate 510 is connected to the second nut seat 509, a second servo motor 511 is provided on the supporting platform 5, and the shaft end of the second servo motor 511 is connected to the end of the second screw 508.

[0064] In a preferred embodiment, the slide clamp body 1 is provided with a plurality of slide grooves 101 arranged side by side, each slide groove 101 is provided with a first hollow hole 103 in the center, each slide groove 101 is provided with a tail pressure plate 2 at one end, the tail pressure plate 2 includes a deformable forward arm 201, a second buckle portion 202 is provided at the end of the forward arm 201, and a first buckle portion 102 is provided at the other end of the slide groove 101, and the first buckle portion 102 and the second buckle portion 202 clamp the two ends of the glass slide.

[0065] The slide holder body 1 is inserted into the slot of the slide scanner after being loaded with the slide. The lens and backlight of the electronic scanning microscope are respectively located on the upper and lower sides of the slide. The first hollow hole 103 in the center of the slide slot 101 is mainly convenient for backlight lighting.

[0066] The front extension arm 201 can be made of plastic or rubber with relatively high hardness. The outwardly extending front extension arm 201 is relatively thin and has certain elasticity and deformation recovery ability.

[0067] In a preferred solution, the first buckle portion 102 is provided with a first inverted cone surface 105, and the second buckle portion 202 is provided with a second inverted cone surface 203. The first inverted cone surface 105 and the second inverted cone surface 203 are respectively abutted against two ends of the glass slide.

[0068] Insert the glass slide obliquely into the glass slide groove 101 and make one end of the glass slide rest against the second buckle portion 202, continue to apply pressure to make the front arm 201 slightly bend and deform until the other end of the glass slide can be lowered and rest against the bottom of the glass slide groove 101, release the glass slide, and the glass slide will be squeezed to the bottom of the first buckle portion 102 and rest against the first inverted cone 105 under the action of the rebound force of the front arm 201, and the glass slide will be clamped immediately.

[0069] In a preferred solution, the tail pressure plate 2 is provided with two forward arms 201 arranged at an angle, and the second buckle portions 202 of the two forward arms 201 abut against two corner positions at one end of the glass slide.

[0070] The first buckle portion 102 has a certain width, which can well fix one end of the glass slide to prevent it from swinging. Since the front arm 201 is thin, two or even more front arms 201 are needed to fix the other end of the glass slide together to prevent it from swinging.

[0071] The sheet clamp body 1 and the tail pressing piece 2 are detachable, and the sheet clamp body 1 and the tail pressing piece 2 are processed separately. A screw hole is provided at one end of the glass slide groove 101, and the tail pressing piece 2 is fixed by a screw.

[0072] An outer lug 106 is provided on one side of the sheet clip body 1, and grooves 107 are provided at both ends of the outer lug 106. The two grooves 107 are symmetrically arranged to facilitate force bearing and convenient for taking and placing by clamping claws or manually.

[0073] A second hollow hole 104 is provided at one end of the glass slide slot 101 close to the first buckle portion 102. When taking out the glass slide, a fingertip can be inserted into the second hollow hole 104 from below the slide clamp and lift the glass slide from this end to release it from the clamped state.

[0074] A plurality of first magnets 108 and a plurality of second magnets 109 are provided at the bottom of the film clip body 1, and the slide scanner is provided with a film clip storage rack 3, and the film clip storage rack 3 is provided with a plurality of film clip slots 301, and each film clip slot 301 is provided with a third magnet 302, and the position of the second magnet 109 is arranged to install the position of the third magnet 302. When the film clip body 1 is inserted into the film clip slot 301 and is in place, each third magnet 302 attracts the second magnet 109 to fix it.

[0075] A slide holder tray 4 is provided under the slide scanner microscope. The slide holder tray 4 is used to position the slide holder body 1. A plurality of fourth magnets 401 are provided on the slide holder tray 4. The positions of the first magnets 108 are arranged according to the distribution of the fourth magnets 401. When the slide holder body 1 is placed on the slide holder tray 4, each fourth magnet 401 attracts each second magnet 109 to complete the positioning.

[0076] The first magnet 108 and the second magnet 109 need to be arranged to avoid interference.

[0077] The camera support frame 9 is also provided with a fill light 1301 for supplementing the light source when previewing photos.

[0078] Normally, when the slide holder tray 4 carrying the slide holder body 1 moves to the bottom of the preview camera 13, the slide holder tray 4 stops, and the preview camera 13 takes a picture to transmit the QR code on the slide and the approximate position of the sample on the slide to the system. This static shooting method makes the image clearer, but it will lose the cycle time.

[0079] Another way is that when the slide tray 4 is about to reach the bottom of the preview camera 13, it slows down and passes through. This way requires the camera to increase the sensitivity and shutter speed, but the image quality will be reduced, and it may still cause blur in low light conditions. Therefore, it is necessary to increase the brightness of the fill light 1301 to compensate for the image quality. As a result, the label on the surface of the glass slide reflects light seriously, causing glare, and the imaging is still not ideal. In addition, the process of slowing down and passing through will also lose some of the beat time.

[0080] In the preferred embodiment, the camera support frame 9 is a door-shaped structure, and connecting plates 901 are provided at both ends of the camera support frame 9. The connecting plates 901 are provided with a front plug rod 902 and a rear plug rod 904. Front plug holes 905 are provided at both ends of the film clamp tray 4. The front plug rod 902 is slidably plugged with the front plug hole 905. Connecting base blocks 903 are provided at both ends of the support platform 5. The connecting base blocks 903 are provided with a rear plug hole 906. The rear plug rod 904 is slidably plugged with the rear plug hole 906. An annular groove 907 is provided at the end of the front plug rod 902. The film clamp tray 4 is provided with a spring top plug 15, one end of the spring top plug 15 rests on the annular groove 907, and a stop plate 908 is provided at the end of the rear plug rod 904. The rear plug rod 904 is sleeved with a first spring 909, and one end of the first spring 909 rests on the stop plate 908.

[0081] When the film holder tray 4 takes the film clip, the end thereof pushes the connecting plate 901 to the farthest original position. When the film holder tray 4 takes the film clip back, the connecting plate 901 is stationary under the holding force of the first spring 909. When the film holder body 1 reaches under the preview camera 13, the end of the spring top plug 15 is just stuck in the annular groove 907, and the card relay pulls the connecting plate 901 forward. At this time, the preview camera 13 and the film holder body 1 are relatively stationary, and the film holder tray 4 can complete the low-light shooting without slowing down the preview camera 13.

[0082] When the film holder tray 4 continues to move forward, the thrust of the first spring 909 is greater than the clamping force of the spring top plug 15 . At this time, the front insertion rod 902 is separated from the film holder tray 4 and the front insertion rod 902 escapes from the front insertion hole 905 .

[0083] In the preferred embodiment, a ball 1501 is provided in the spring top plug 15, and the ball 1501 is used to abut against the annular groove 907. A slidable ball abutment block 1502 is provided on one side of the ball 1501. A threaded rear adjustment block 1504 is also provided in the spring top plug 15, and a second spring 1503 is provided between the rear adjustment block 1504 and the ball abutment block 1502.

[0084] The rear adjustment stopper 1504 can adjust the holding force of the second spring 1503 and adjust the pressing force of the ball 1501 on the annular groove 907 .

[0085] The above embodiments are only preferred technical solutions of the present invention and should not be regarded as limiting the present invention. The protection scope of the present invention shall be the technical solutions recorded in the claims, including equivalent replacement solutions of the technical features in the technical solutions recorded in the claims. That is, equivalent replacement improvements within this scope are also within the protection scope of the present invention.

Claims

1. A compact slide automatic scanning device, characterized by: The invention comprises an electron scanning microscope (11), wherein the electron scanning microscope (11) comprises a liftable lifting platform (8), wherein the liftable platform (8) is provided with a two-dimensional displacement platform, wherein the two-dimensional displacement platform comprises a connecting bottom plate (7), wherein the connecting bottom plate (7) is used to connect with the liftable platform (8) of the electron scanning microscope (11), wherein a movable bearing platform (5) is provided at the upper end of the electron scanning microscope (11), wherein a movable film clip tray (4) is provided on the bearing platform (5) along the length direction, wherein the moving directions of the film clip tray (4) and the bearing platform (5) are perpendicular, wherein a film clip storage rack (3) which can move up and down is provided at one end of the bearing platform (5), wherein the film clip storage rack (3) is a frame-shaped structure with two ends connected, wherein the through end of the film clip storage rack (3) faces the length direction of the bearing platform (5), wherein a plurality of film clip slots (301) are provided on the film clip storage rack (3) along the height direction, and a preview camera (13) is provided at one end of the bearing platform (5) close to the film clip storage rack (3).

2. The compact slide automatic scanning device according to claim 1, characterized in that: A hollow slit (12) is provided at one end of the support platform (5), a control panel (6) is provided in the hollow slit (12), a first photoelectric proximity sensor (601) and a second photoelectric proximity sensor (602) are provided on the control panel (6), the first photoelectric proximity sensor (601) is used to detect the origin position of the film clip tray (4), and the second photoelectric proximity sensor (602) is used to detect the origin position of the support platform (5).

3. The compact slide automatic scanning device according to claim 2, characterized in that: A first guide rail (502) and a first lead screw (504) are provided on the support platform (5); the film clamp tray (4) is slidably connected to the first guide rail (502) via a slider; a first nut seat (505) is sleeved on the first lead screw (504); one end of the film clamp tray (4) is connected to the first nut seat (505); a first servo motor (503) is provided on the support platform (5); and a shaft end of the first servo motor (503) is connected to an end of the first lead screw (504).

4. The compact slide automatic scanning device according to claim 2, characterized in that: A third guide rail (705) is provided at the lower end of the bearing platform (5), the connecting base plate (7) is slidably connected to the third guide rail (705) via a slider, a third servo motor (702) is provided at the lower end of the bearing platform (5), a third lead screw (703) is connected to the shaft end of the third servo motor (702), a third screw nut seat (704) is sleeved on the third lead screw (703), and the third screw nut seat (704) is connected to the connecting base plate (7).

5. The compact slide automatic scanning device according to claim 2, characterized in that: A plurality of conductive posts (612) are provided on the control board (6); transition blocks (609) are provided at the ends of the first photoelectric proximity sensor (601) and the second photoelectric proximity sensor (602); the outlet ends (613) of the first photoelectric proximity sensor (601) and the second photoelectric proximity sensor (602) are electrically connected to the conductive sleeves (614); the transition block (609) is provided with a plurality of conductive sleeves (614); each conductive sleeve (614) is sleeved with each conductive post (612); a mounting ear (610) is provided on one side of the transition block (609); a threaded sleeve (611) is embedded in the control board (6); a screw passes through the mounting ear (610) to be threadedly connected to the threaded sleeve (611).

6. The compact slide automatic scanning device according to claim 1, characterized in that: Stop ridges (303) are provided at both side ends of the film clip slot (301), and third magnets (302) are provided on the stop ridges (303). A plurality of first magnets (108) and a plurality of second magnets (109) are provided at the bottom of the film clip body (1), and a plurality of fourth magnets (401) are provided on the film clip tray (4). Each third magnet (302) is used to attract each second magnet (109), and each fourth magnet (401) is used to attract each second magnet (109).

7. The compact slide automatic scanning device according to claim 6, characterized in that: A vertical extension arm (501) is provided at one end of the support platform (5) close to the film clip storage rack (3), and a second guide rail (507) is provided on the extension arm (501). A slider is provided on one side of the film clip storage rack (3) and is slidably connected to the second guide rail (507). A jumper plate (510) is also provided on the side of the film clip storage rack (3). A second screw nut seat (509) is sleeved on the second lead screw (508), and an end of the jumper plate (510) is connected to the second screw nut seat (509). A second servo motor (511) is provided on the support platform (5), and an axis end of the second servo motor (511) is connected to an end of the second lead screw (508).

8. The compact slide automatic scanning device according to claim 1, characterized in that: The slide holder body (1) is provided with a plurality of glass slide grooves (101) arranged side by side, each glass slide groove (101) is provided with a first hollow hole (103) in the center, each glass slide groove (101) is provided with a tail pressing piece (2) at one end, the tail pressing piece (2) comprises a deformable front extending arm (201), a second buckle portion (202) is provided at the end of the front extending arm (201), and a first buckle portion (102) is provided at the other end of the glass slide groove (101), the first buckle portion (102) and the second buckle portion (202) clamping the two ends of the glass slide.

9. The compact slide automatic scanning device according to claim 1, characterized in that: The camera support frame (9) is a door-shaped structure. Both ends of the camera support frame (9) are provided with connecting plates (901). The connecting plates (901) are provided with a front plug rod (902) and a rear plug rod (904). Both ends of the film holder tray (4) are provided with front plug holes (905). The front plug rod (902) is slidably plugged with the front plug hole (905). Both ends of the bearing platform (5) are provided with plug-in base blocks (903). The plug-in base blocks (903) are provided with a rear plug hole (906). The rear plug rod (904) is slidably plugged into the rear plug hole (906), an annular groove (907) is provided at the end of the front plug rod (902), a spring top plug (15) is provided on the sheet clamp tray (4), one end of the spring top plug (15) abuts against the annular groove (907), a stopper sheet (908) is provided at the end of the rear plug rod (904), and the rear plug rod (904) is sleeved with a first spring (909), one end of the first spring (909) abuts against the stopper sheet (908).

10. The compact slide automatic scanning device according to claim 9, characterized in that: A ball (1501) is provided in the spring top plug (15), and the ball (1501) is used to abut against the annular groove (907). A slidable ball abutting block (1502) is provided on one side of the ball (1501). A threaded rear adjustment block (1504) is also provided in the spring top plug (15), and a second spring (1503) is provided between the rear adjustment block (1504) and the ball abutting block (1502).

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