Toothpaste for removing smoke spots and preparation method thereof

Abstract

The invention discloses toothpaste for removing smoke spots and a preparation method thereof, and relates to the technical field of oral health, and the toothpaste comprises the following components in parts by weight: 30-38 parts of a friction agent, 2-3 parts of a fat-dissolving cleaning agent, 1-3 parts of an oxygenolysis component, 1-2 parts of a surfactant, 4.5-6 parts of an enamel protective agent, 0.7-1.5 parts of an antibacterial and refreshing agent, 20-25 parts of a wetting agent, 0.2-0.5 part of an anti-caries component and 20-50 parts of a basic solvent; the fat-dissolving cleaning agent is polyoxyethylene lauryl ether, and the oxygenolysis component is urea peroxide. Through the synergistic effect of the fat-dissolving cleaning agent (polyoxyethylene lauryl ether) and the oxygenolysis component (urea peroxide), stubborn pigments such as tar and nicotine in tobaccos can be rapidly dissolved, and deeply deposited smoke stain pigment molecules are decomposed through active oxygen, so that the teeth are recovered to be naturally bright and white.

Description

Technical Field

[0001] The invention relates to the technical field of oral health, in particular to a toothpaste for removing smoke stains and a preparation method thereof. Background Art

[0002] Smoking is a common behavior worldwide. With the increase in the number of smokers, the oral health problems caused by long-term smoking have also received more and more attention. In particular, the components in tobacco smoke, such as tar and nicotine, will form stubborn stains on the surface of teeth, which not only has a significant impact on the beauty of teeth, but also poses a potential hazard to oral health. Tar and nicotine have extremely strong adhesion and are easily embedded in tiny cracks and rough areas on the surface of teeth, gradually forming dark stains. Once these stains are formed, it is difficult to remove them through daily brushing or the cleaning action of ordinary toothpaste, and they will further aggravate the roughness of the tooth surface, leading to more pigment deposition, forming a vicious cycle of "smoke stains-attachment-reattachment".

[0003] The presence of smoke stains not only affects the appearance, causing the teeth to turn yellow and black, giving people an impression of uncleanliness and unhealthiness, but may also affect the biofilm structure on the surface of the teeth and promote the formation of dental plaque and tartar. At the same time, the acidic components in tobacco will also corrode the enamel, further weakening the protective barrier of the teeth and making the teeth more vulnerable to external damage. This acid corrosion may also lead to the loss of the mineralized layer on the surface of the teeth, making the teeth more sensitive to external stimuli. In addition, a large amount of tobacco chemical components will remain in the mouth during the smoking process. After these substances react with the bacteria in the mouth, they release unpleasant odors, becoming an important source of bad breath in the mouth, further affecting the social image and mental health of smokers.

[0004] Although the whitening toothpastes currently on the market have a certain cleaning effect on common stains (such as tea stains and coffee stains), due to the special properties of smoke stains, it is difficult for conventional toothpastes to effectively deal with the complex problem of smoke stains. Many whitening toothpastes rely on high-hardness abrasives (such as calcium carbonate or aluminum oxide) for physical cleaning. Although they can remove some stains on the surface of the teeth to a certain extent, long-term use may cause irreversible damage to the enamel and increase the roughness of the tooth surface. Other toothpastes use chemical bleaching ingredients (such as peroxide) to decompose stains. Although this can temporarily whiten teeth, it may also cause side effects such as tooth sensitivity and gum irritation, posing a potential threat to dental health. In addition, most toothpaste products lack an effective protection mechanism after removing stains and cannot inhibit the re-attachment of pigments, which makes the whitening effect difficult to last.

[0005] More importantly, current toothpaste products generally ignore the special needs of smokers, such as removing smoke stains while alleviating bad breath caused by smoking. The residual tobacco components in the smoking process combine with the metabolism of oral bacteria to produce volatile substances with bad smells. The simple whitening function is difficult to fully solve the oral problems of smokers. The existence of these problems has made the oral care needs of smokers not fully met for a long time. Summary of the invention

[0006] The purpose of this section is to summarize some aspects of embodiments of the present invention and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the specification abstract and the invention title of this application to avoid blurring the purpose of this section, the specification abstract and the invention title, and such simplifications or omissions cannot be used to limit the scope of the present invention.

[0007] In view of the above problems and / or the problems existing in existing toothpastes for removing smoke stains, the present invention is proposed.

[0008] Therefore, the problem to be solved by the present invention is how to provide a toothpaste for removing smoke stains.

[0009] In order to solve the above technical problems, the present invention provides the following technical solutions: a toothpaste for removing smoke stains, comprising, by weight, 30 to 38 parts of abrasives, 2 to 3 parts of fat-dissolving detergents, 1 to 3 parts of oxidative decomposition components, 1 to 2 parts of surfactants, 4.5 to 6 parts of enamel protective agents, 0.7 to 1.5 parts of antibacterial and fresheners, 20 to 25 parts of wetting agents, 0.2 to 0.5 parts of anti-caries components, and 20 to 50 parts of basic solvents; the fat-dissolving detergent is polyoxyethylene lauryl alcohol ether, and the oxidative decomposition component is urea peroxide.

[0010] As a preferred embodiment of the toothpaste for removing smoke stains of the present invention, the mass ratio of the polyoxyethylene lauryl alcohol ether to urea peroxide is 2.5:2.

[0011] As a preferred embodiment of the toothpaste for removing smoke stains of the present invention, the abrasive is microcrystalline silicon dioxide and aluminum hydroxide, wherein the mass ratio of microcrystalline silicon dioxide to aluminum hydroxide is 25-30:5-8.

[0012] As a preferred embodiment of the toothpaste for removing smoke stains of the present invention, the surfactant is sodium lauroyl glutamate, wherein the mass ratio of sodium lauroyl glutamate is 1-2.

[0013] As a preferred embodiment of the toothpaste for removing smoke stains of the present invention, the tooth enamel protective agent is nano-hydroxyapatite and chitosan, wherein the mass ratio of nano-hydroxyapatite to chitosan is 4-5:0.5-1.

[0014] As a preferred embodiment of the toothpaste for removing smoke stains of the present invention, the antibacterial and freshening agents are eucalyptus extract and tea tree oil, wherein the mass ratio of eucalyptus extract to tea tree oil is 0.5-1:0.2-0.5.

[0015] As a preferred embodiment of the toothpaste for removing smoke stains of the present invention, the wetting agent is glycerol, wherein the mass ratio of glycerol is 20-25.

[0016] As a preferred embodiment of the toothpaste for removing smoke stains of the present invention, the anti-caries component is sodium fluoride, wherein the mass ratio of sodium fluoride is 0.2-0.5.

[0017] As a preferred embodiment of the toothpaste for removing smoke stains of the present invention, the base solvent is water, wherein the mass ratio of water is 20-25.

[0018] Another object of the present invention is to provide a method for preparing toothpaste for removing smoke stains.

[0019] A method for preparing a toothpaste for removing smoke stains comprises the following steps:

[0020] Step 1: Add glycerin and deionized water in a formula ratio into a reactor and stir to form a uniform base liquid. Then, slowly add sodium lauroyl glutamate and continue stirring until it is completely dissolved to form a transparent and uniform liquid phase system.

[0021] Step 2: Premix polyoxyethylene lauryl alcohol ether with a small amount of glycerol and disperse it by ultrasonic disperser. Disperse nanohydroxyapatite with deionized water and treat it with ultrasound. At room temperature, gradually add urea peroxide to the base liquid while stirring at a low speed until it is completely dissolved. After sodium fluoride is pre-dissolved in deionized water, slowly add it to the mixed solution and keep stirring evenly to ensure its uniform distribution in the liquid phase system.

[0022] Step 3: gradually add microcrystalline silicon dioxide and aluminum hydroxide to the base liquid, stir using a high-speed stirring device to form a stable suspension, then slowly add chitosan, continue stirring until completely dissolved, add eucalyptus extract and tea tree oil in proportion, stir until evenly dispersed, and after mixing, place the liquid phase system under vacuum conditions and stir;

[0023] Step 4: During the stirring process, adjust the ratio of glycerin and water to control the viscosity of the mixture within the range of 20,000 to 30,000 cps, and cool the mixture to room temperature for sealed packaging.

[0024] The beneficial effects of the present invention are as follows: (1) The present invention can quickly dissolve stubborn pigments such as tar and nicotine in tobacco through the synergistic effect of the fat-dissolving detergent (polyoxyethylene lauryl alcohol ether) and the oxidative decomposition component (urea peroxide), and decompose the deeply deposited tobacco stain pigment molecules through active oxygen, so that the teeth can be restored to natural whiteness. The combination of abrasives (microcrystalline silicon dioxide and aluminum hydroxide) provides a mild and efficient physical cleaning ability, effectively removing stubborn stains on the surface of teeth while avoiding excessive wear on tooth enamel. Antibacterial fresheners (eucalyptus extract and tea tree oil) further inhibit the growth of oral bacteria and reduce the odor caused by smoking, thereby achieving comprehensive cleaning and lasting freshness of the oral cavity.

[0025] (2) The use of enamel protectors (nano-hydroxyapatite and chitosan) can repair the micropores and cracks on the tooth surface, reduce the damage that may occur during the cleaning process, and form a protective film on the tooth surface to reduce the re-attachment of tobacco pigments and bacteria. The anti-caries ingredient sodium fluoride further reduces the risk of caries by enhancing the acid resistance of enamel and inhibiting plaque formation, helping smokers maintain dental health while effectively removing smoke stains. The entire formula is gentle and safe, avoiding the tooth sensitivity problem that may be caused by high-hardness abrasives or strong bleaching agents in traditional toothpaste. DETAILED DESCRIPTION

[0026] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below.

[0027] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0028] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0029] Example 1

[0030] A toothpaste ratio for removing smoke stains and a preparation method thereof, comprising the following components by weight: 28 parts of microcrystalline silicon dioxide, 6 parts of aluminum hydroxide, 1.5 parts of sodium lauroyl glutamate, 4.5 parts of nano-hydroxyapatite, 0.8 parts of chitosan, 0.8 parts of eucalyptus extract, 0.3 parts of tea tree oil, 22 parts of glycerol, and 30.8 parts of water. The components of polyoxyethylene lauryl alcohol ether and urea peroxide are shown in Table 1.

[0031] Table 1 Test data table

[0032]

[0033]

[0034] This embodiment also provides a method for preparing a toothpaste for removing smoke stains, which comprises the following steps:

[0035] Step 1: Add the formula ratio of glycerin and deionized water into the reactor, stir at 30-40°C to ensure that the two are fully mixed to form a uniform base liquid. Then, slowly add sodium lauroyl glutamate and continue stirring until it is completely dissolved to form a transparent and uniform liquid phase system, providing a good dispersion environment for the subsequent addition of ingredients.

[0036] Step 2: Pre-mix polyoxyethylene lauryl alcohol ether with a small amount of glycerol and disperse it through an ultrasonic disperser for 3 to 5 minutes to ensure uniform distribution of the fat-dissolving cleanser. Nanohydroxyapatite is dispersed with deionized water and treated with ultrasound for 5 minutes to prevent particle agglomeration and improve dispersion stability. At room temperature (<30°C), carbamide peroxide is gradually added to the base liquid while stirring at a low speed until completely dissolved to avoid premature release of active oxygen. After sodium fluoride is pre-dissolved in deionized water, it is slowly added to the mixed solution, maintaining uniform stirring to ensure its uniform distribution in the system.

[0037] Step 3: Gradually add microcrystalline silicon dioxide and aluminum hydroxide to the base liquid, and use a high-speed stirring device (800-1000rpm) to stir for 15 minutes to ensure uniform distribution of the abrasive and form a stable suspension. Subsequently, slowly add chitosan and continue stirring until completely dissolved. Add eucalyptus extract and tea tree oil according to the formula ratio and stir for 10 minutes to evenly disperse the antibacterial freshener. After mixing, place the system under vacuum conditions (-0.08-0.1MPa) and stir for 10 minutes to remove bubbles generated during the mixing process and ensure the uniform texture of the toothpaste.

[0038] Step 4: During the stirring process, adjust the ratio of glycerin and water according to the actual viscosity requirements to control the viscosity of the mixture within the range of 20,000 to 30,000 cps. Cool the mixture to room temperature (25 to 30°C) to ensure that the stability of the active ingredients is not affected by high temperatures. After cooling, use a hose filling machine to fill the toothpaste into the hose and seal it with high-frequency heat sealing equipment to ensure the airtightness of the package. After filling, conduct finished product inspections on the product for appearance, uniformity, viscosity and pH to ensure that the quality meets the expected standards.

[0039] Comparative Example 1

[0040] Comparative Example 1 of a toothpaste for removing smoke stains and a preparation method thereof includes the following components, by weight: 28 parts of microcrystalline silicon dioxide, 6 parts of aluminum hydroxide, 1.5 parts of sodium lauroyl glutamate, 2.5 parts of urea peroxide, 4.5 parts of nano-hydroxyapatite, 0.8 parts of chitosan, 0.8 parts of eucalyptus extract, 0.3 parts of tea tree oil, 24.5 parts of glycerin, and 30.8 parts of water.

[0041] The preparation method of the material is the same as that of Example 1.

[0042] In this example, the component (PEG-40) that dissolves tar and nicotine is missing and is replaced by glycerol, which is expected to weaken the removal effect on oily cigarette stains.

[0043] Comparative Example 2

[0044] Comparative Example 2, which is a toothpaste for removing smoke stains and a preparation method thereof, includes the following components, by weight: 28 parts of microcrystalline silicon dioxide, 6 parts of aluminum hydroxide, 1.5 parts of sodium lauroyl glutamate, 2.5 parts of polyoxyethylene lauryl alcohol ether, 4.5 parts of nano-hydroxyapatite, 0.8 parts of chitosan, 0.8 parts of eucalyptus extract, 0.3 parts of tea tree oil, 24.5 parts of glycerin, and 30.8 parts of water.

[0045] The preparation method of the material is the same as that of Example 1.

[0046] In this example, the oxidant (urea peroxide) for decomposing stubborn pigment molecules is absent and replaced by water, which is expected to weaken the removal effect on stubborn smoke stains.

[0047] Comparative Example 3

[0048] Comparative Example 1 of a toothpaste for removing smoke stains and a preparation method thereof includes the following components, by weight: 33.3 parts of microcrystalline silicon dioxide, 6 parts of aluminum hydroxide, 1.5 parts of sodium lauroyl glutamate, 2.5 parts of urea peroxide, 0.8 parts of eucalyptus extract, 0.3 parts of tea tree oil, 24.5 parts of glycerin, and 30.8 parts of water.

[0049] The preparation method of the material is the same as that of Example 1.

[0050] In this example, nano-hydroxyapatite and chitosan were removed and replaced with microcrystalline silica, which is expected to increase the reattachment rate of smoke stains and increase enamel wear.

[0051] Example 2

[0052] The toothpastes prepared in Example 1 and Comparative Examples 1 to 3 were subjected to enamel color measurement, and the measurement process was as follows:

[0053] (1) Preparation of in vitro tooth specimens: Fresh calf anterior teeth were selected, the root tissue was removed, and after ultrasonic cleaning, the tooth specimens were stored in 0.1 M phosphate buffer (PBS, pH 7.4). Teeth with no cracks, caries, or stains on the crown surface were selected as subsequent experimental models.

[0054] (2) Staining of in vitro tooth specimens:

[0055] Pretreatment: Immerse the prepared bovine tooth specimen in 1% hydrochloric acid, stir for 60 seconds, take it out and rinse it with clean water. Then immerse it in saturated sodium carbonate solution, stir for 60 seconds, take it out and rinse it with clean water. Finally, immerse it in 1% phytic acid solution, stir for 60 seconds, take it out and rinse it with clean water.

[0056] Prepare dye solution: Add black tea to hot water and stir evenly, then cool. Add FeCl3 solution maintained at 4°C before use. The final concentration of each component is 4.0g / L black tea and 0.05g / L FeCl3.

[0057] Staining: Immerse the pre-treated bovine tooth specimen in the staining solution and place it at 4°C for 7 days. After soaking, take out the bovine tooth and rinse it with water for 1-2 minutes.

[0058] (3) Colorimeter to measure L* value before and after brushing

[0059] After brushing teeth, a sample of the brushing solution was taken and the Fe content in the solution was detected by ICP-MS. 3+ 、Al 3+ The concentration was measured, and the color of the enamel was measured with a colorimeter (L* before brushing). The specimens were randomly assigned to the sample group and the control group, with 3 pieces in each group. There was no significant difference between the groups (P>0.05). The specimens were brushed with the test substance and the control substance respectively. The sample group used it twice a day and brushed for 3 minutes. During the treatment interval, the bovine tooth specimens were immersed in artificial saliva, and the environment was maintained at 37°C to simulate the oral environment. The total test cycle was 7 days. After the brushing cycle, the color of the enamel was measured again with a colorimeter (L* after brushing), and the difference in L* values ​​before and after brushing was calculated, ΔL*=L*(after brushing)-L*(before brushing).

[0060] (4) Results analysis

[0061] Perform t-test statistical analysis on the ΔL* value. If the ΔL* value of the sample group is greater than that of the control group and there is a significant difference (P<0.05), the sample has a stain removal and whitening effect.

[0062] The measurement data are shown in Table 2.

[0063] Table 2 Measurement results

[0064]

[0065]

[0066] In summary, (1) the present invention can quickly dissolve stubborn pigments such as tar and nicotine in tobacco through the synergistic effect of the fat-dissolving detergent (polyoxyethylene lauryl alcohol ether) and the oxidative decomposition component (urea peroxide), and decompose the deeply deposited tobacco stain pigment molecules through active oxygen, so that the teeth can be restored to natural whiteness. The combination of abrasives (microcrystalline silicon dioxide and aluminum hydroxide) provides a gentle and efficient physical cleaning ability, effectively removing stubborn stains on the surface of teeth while avoiding excessive wear on tooth enamel. Antibacterial fresheners (eucalyptus extract and tea tree oil) further inhibit the growth of oral bacteria and reduce the odor caused by smoking, thereby achieving comprehensive cleaning and lasting freshness of the oral cavity.

[0067] (2) The use of enamel protectors (nano-hydroxyapatite and chitosan) can repair the micropores and cracks on the tooth surface, reduce the damage that may occur during the cleaning process, and form a protective film on the tooth surface to reduce the re-attachment of tobacco pigments and bacteria. The anti-caries ingredient sodium fluoride further reduces the risk of caries by enhancing the acid resistance of enamel and inhibiting plaque formation, helping smokers maintain dental health while effectively removing smoke stains. The entire formula is gentle and safe, avoiding the tooth sensitivity problem that may be caused by high-hardness abrasives or strong bleaching agents in traditional toothpaste.

[0068] (3) Through the reasonable wetting agent ratio (glycerin), the toothpaste of the present invention has a fine texture and good wettability, is not easy to dry and clump during storage, has rich foam during use, is easy to apply and clean, and significantly improves the user's comfort. This formula is specially designed for smokers. It not only has a significant effect on removing smoke stains, but also can effectively solve the oral odor and dental health problems caused by smoking, meet the special needs of smokers, fill the functional gap in the market, and provide users with high-quality oral care solutions.

[0069] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A toothpaste for removing smoke stains, characterized in that: The composition comprises, by weight, 30 to 38 parts of abrasive, 2 to 3 parts of fat dissolving cleaning agent, 1 to 3 parts of oxidative decomposition component, 1 to 2 parts of surfactant, 4.5 to 6 parts of tooth enamel protective agent, 0.7 to 1.5 parts of antibacterial and freshening agent, 20 to 25 parts of wetting agent, 0.2 to 0.5 parts of anti-caries component, and 20 to 50 parts of base solvent; The fat dissolving detergent is polyoxyethylene lauryl alcohol ether, and the oxidative decomposition component is urea peroxide.

2. The toothpaste for removing smoke stains according to claim 1, characterized in that: The mass ratio of the polyoxyethylene lauryl alcohol ether to urea peroxide is 2.5:

2.

3. The toothpaste for removing smoke stains according to claim 1 or 2, characterized in that: The friction agent is microcrystalline silicon dioxide and aluminum hydroxide, wherein the mass ratio of microcrystalline silicon dioxide to aluminum hydroxide is 25-30:5-8.

4. The toothpaste for removing smoke stains according to claim 3, characterized in that: The surfactant is sodium lauroyl glutamate, wherein the mass ratio of sodium lauroyl glutamate is 1-2.

5. The toothpaste for removing smoke stains according to any one of claims 1, 2 and 4, characterized in that: The tooth enamel protective agent is nano-hydroxyapatite and chitosan, wherein the mass ratio of nano-hydroxyapatite to chitosan is 4-5:0.5-1.

6. The toothpaste for removing smoke stains according to claim 5, characterized in that: The antibacterial and refreshing agent is eucalyptus extract and tea tree oil, wherein the mass ratio of the eucalyptus extract to the tea tree oil is 0.5-1:0.2-0.

5.

7. The toothpaste for removing smoke stains according to claim 6, characterized in that: The wetting agent is glycerol, wherein the mass ratio of glycerol is 20-25.

8. The toothpaste for removing smoke stains according to claim 6 or 7, characterized in that: The anti-caries component is sodium fluoride, wherein the mass ratio of sodium fluoride is 0.2-0.

5.

9. The toothpaste for removing smoke stains according to claim 8, characterized in that: The basic solvent is water, wherein the mass ratio of water is 20-25.

10. A method for preparing a toothpaste for removing smoke stains as claimed in any one of claims 1 to 9, characterized in that: The following steps are included: Step 1: Add glycerin and deionized water in a formula ratio into a reactor and stir to form a uniform base liquid. Then, slowly add sodium lauroyl glutamate and continue stirring until it is completely dissolved to form a transparent and uniform liquid phase system. Step 2: Premix polyoxyethylene lauryl alcohol ether with a small amount of glycerol and disperse it by ultrasonic disperser. Disperse nanohydroxyapatite with deionized water and treat it with ultrasound. At room temperature, gradually add urea peroxide to the base liquid while stirring at a low speed until it is completely dissolved. After sodium fluoride is pre-dissolved in deionized water, slowly add it to the mixed solution and keep stirring evenly to ensure its uniform distribution in the liquid phase system. Step 3: gradually add microcrystalline silicon dioxide and aluminum hydroxide to the base liquid, stir using a high-speed stirring device to form a stable suspension, then slowly add chitosan, continue stirring until completely dissolved, add eucalyptus extract and tea tree oil in proportion, stir until evenly dispersed, and after mixing, place the liquid phase system under vacuum conditions and stir; Step 4: During the stirring process, adjust the ratio of glycerin and water to control the viscosity of the mixed solution within the range of 20,000 to 30,000 cps, and cool the mixed solution to room temperature for sealed packaging.

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