A keloid mechanical balance microneedle, a preparation method and an application in preparing a product for preventing keloid recurrence

CN119940007BActive Publication Date: 2026-06-23DERMATOLOGY HOSPITAL SOUTHERN MEDICAL UNIV (GUANGDONG PROVINCIAL DERMATOLOGY HOSPITAL GUANGDONG PROVINCIAL CENT FOR STI & SKIN DISEASES CONTROL & PREVENTION RES CENT FOR LEPROSY CONTROL & PREVENTION CHINA)

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
DERMATOLOGY HOSPITAL SOUTHERN MEDICAL UNIV (GUANGDONG PROVINCIAL DERMATOLOGY HOSPITAL GUANGDONG PROVINCIAL CENT FOR STI & SKIN DISEASES CONTROL & PREVENTION RES CENT FOR LEPROSY CONTROL & PREVENTION CHINA)
Filing Date
2025-01-06
Publication Date
2026-06-23

AI Technical Summary

Technical Problem

Existing treatments are ineffective in resolving the recurrence of keloids and often cause uneven collagen degradation within the scar, further exacerbating the imbalance of the biomechanical environment.

Method used

By constructing a finite element model of keloids and skin, the microneedle array model with the smallest mechanical difference was selected, and a keloid mechanical balance microneedle was prepared to evenly distribute the stress between the keloid and the surrounding skin.

Benefits of technology

It achieves uniform stress distribution between keloids and surrounding skin, effectively preventing keloid recurrence.

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Abstract

A keloid mechanical balance microneedle, a preparation method and an application in preparing a product for preventing keloid recurrence, wherein the preparation method of the keloid mechanical balance microneedle is as follows: firstly, according to the average thickness of postoperative scar tissue of an object, a preliminary skin-scar finite element model composed of a scar structure and a skin structure is constructed, and the thickness of each position of the whole scar structure is the same; then, the keloid mechanical balance microneedle is finally obtained through four steps. The keloid mechanical balance microneedle is prepared according to the postoperative scar tissue of an object, and through the keloid mechanical balance microneedle, the stress distribution between the keloid and the surrounding skin can be uniform, and the keloid recurrence can be effectively prevented.
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