Liquid separation multi-way head, collecting device and in-situ cleaning and material separation system and method

Through the coordination of the cleaning multi-way valve group of the in-situ cleaning material separation system and the feed multi-way valve, cleaning liquid and gas is used for in-situ cleaning, cross-contamination problem during reagent switching in the prior art is solved, and the safety, efficiency and convenience of disassembly are improved.

CN119953661APending Publication Date: 2025-05-09HANGZHOU YANJIN TECHNOLOGY CO LTD

Patent Information

Application Number
CN202510121069.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-24
Publication Date
2025-05-09

AI Technical Summary

Technical Problem

Existing dispensing equipment is prone to cross-contamination when switching different reagents, making it difficult to keep clean. It is prone to contamination at the valve entrance when switching each time, resulting in low safety, efficiency and convenience of dispensing.

Method used

It provides an in-situ cleaning and dispensing system, including a feeding device group, a cleaning pipeline group, a cleaning multi-way valve group, a feeding pipeline group, a feeding multi-way valve and a feeding equipment. By combining the cleaning multi-way valve group and a feeding multi-way valve, cleaning liquid and gas are used to clean, feed and dispens the pipeline to ensure the cleanliness of the pipeline.

Benefits of technology

It effectively avoids cross-contamination problems during material storage, access and switching, and greatly improves the safety, efficiency and convenience of packaging.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119953661A_ABST
    Figure CN119953661A_ABST
Patent Text Reader

Abstract

The invention relates to a liquid separation multi-way head, a collecting device and an in-situ cleaning and material separation system and method. The in-situ cleaning and distributing system comprises a feeding device group, a cleaning pipeline group, a cleaning multi-way valve group, a conveying pipeline group, a conveying multi-way valve and distributing equipment, each material supply device comprises a material supply source and a reversing valve, the material supply source of at least one material supply device is gas, the material supply source of at least one material supply device is cleaning liquid, and the material supply source of at least one material supply device is a material to be subpackaged; the multiple feeding devices are connected to the cleaning multi-way valve set in parallel through the cleaning pipeline set and connected to the material conveying multi-way valve in parallel through the material conveying pipeline set, and the material distributing equipment is connected to the material conveying multi-way valve in a driving mode. The cleaning multi-way valve set, the material conveying multi-way valve and all the reversing valves can be matched with one another to switch the provided material supply sources and the flowing paths of the material supply sources, and in-situ cleaning, in-situ material supply and in-situ material distribution are completed.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention relates to the field of material packaging, and in particular to a liquid separation multi-way head, a collecting device, an in-situ cleaning material separation system and a method. Background Art

[0002] When different reagents need to be packaged for use, it is very inconvenient to use different packaging equipment. However, when switching between the same packaging equipment, cross-contamination is likely to occur between the pipelines, making it difficult to keep them clean. In addition, each time different reagents are switched, contamination is likely to occur at the access valve port. The overall packaging safety, efficiency, and convenience are all low. Summary of the invention

[0003] In view of this, it is necessary to provide an in-situ cleaning dispensing system.

[0004] An in-situ cleaning and distributing system comprises a feeding device group, a cleaning pipeline group, a cleaning multi-way valve group, a material conveying pipeline group, a material conveying multi-way valve and a distributing device;

[0005] The feeding device group includes a plurality of feeding devices, each of which includes a feeding source and a reversing valve, the feeding source of at least one of the feeding devices is gas, the feeding source of at least one of the feeding devices is cleaning liquid, and the feeding source of at least one of the feeding devices is a material to be packaged; the reversing valve has at least three valve ports, which are respectively defined as an inner valve port, a cleaning valve port and a feeding valve port; wherein the inner valve port is connected to the feeding source, the cleaning valve port is connected to one of the valve ports of the cleaning multi-way valve group through a cleaning pipeline in the cleaning pipeline group; the feeding valve port is connected to one of the feeding inlets of the feeding multi-way valve through a feeding pipeline in the feeding pipeline group; the material distributing device is driven and connected to the feeding outlet of the feeding multi-way valve;

[0006] The cleaning multi-way valve group, the material feeding multi-way valve, and each of the reversing valves can cooperate with each other to switch the provided material supply source and the flow path of the material supply source to complete in-situ cleaning, in-situ feeding, and in-situ material distribution.

[0007] The present invention also provides a liquid-separating multi-way head, the liquid-separating multi-way head comprises a main flow channel and a plurality of branch flow channels, one end of the plurality of branch flow channels is connected to the same end of the main flow channel;

[0008] The plurality of branch flow channels are arranged in a circumferential direction along the central axis of the main flow channel, and an angle is formed between the central axis of each branch flow channel and the central axis of the main flow channel, and the angle is a right angle or an acute angle.

[0009] The present invention also provides a collection device, comprising a storage element and a collection tube, wherein the collection tube has an input port and an output port, the output port is connected to the storage element, and the object to be collected enters the collection tube from the input port and enters the storage element through the output port;

[0010] Wherein, an anti-return structure is further provided between the input port and the output port, and the anti-return structure is used to prevent the objects to be collected that enter the storage element from flowing back to the output port or volatilizing.

[0011] The present invention also provides an initialization method for an in-situ cleaning dispensing system, comprising the above-mentioned in-situ cleaning dispensing system, defining a feeding device whose feeding source is gas as an air intake device, defining a feeding device whose feeding source is cleaning liquid as a liquid intake device, and defining a feeding device whose feeding source is a material to be packaged as a feeding device; the method comprises:

[0012] S0, pre-sterilizing the liquid inlet device, the air inlet device and the feeding device;

[0013] S1, providing cleaning liquid and switching the flow path of the cleaning liquid through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the cleaning pipeline and the material delivery pipeline connected to the air inlet device;

[0014] S2, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, gas is provided and the flow path of the gas is switched, the cleaning liquid in the cleaning pipeline and / or the material delivery pipeline connected to the air intake device is emptied by the gas of the air intake device, and the cleaning pipeline and / or the material delivery pipeline connected to the air intake device is dried;

[0015] S3, providing cleaning liquid and switching the flow path of the cleaning liquid through the cooperation of the cleaning multi-way valve group, the feeding multi-way valve and each of the reversing valves, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the cleaning pipeline and the feeding pipeline connected to the feeding device;

[0016] S4, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, gas is provided and the gas flow path is switched, and the gas from the air intake device is used to empty the cleaning liquid in the cleaning pipeline and the material delivery pipeline connected to the feeding device, and the cleaning pipeline and the material delivery pipeline connected to the feeding device are dried.

[0017] The present invention provides a material dispensing method for an in-situ cleaning material dispensing system, comprising the above-mentioned in-situ cleaning material dispensing system, defining a feeding device whose material supply source is gas as an air intake device, defining a feeding device whose material supply source is a cleaning liquid as a liquid intake device, and defining a feeding device whose material supply source is a material to be packaged as a feeding device; defining a path formed by the material supply source, a reversing valve, a cleaning pipeline and a cleaning multi-way valve of the liquid intake device as a first cleaning output branch, defining a path formed by the material supply source, a reversing valve, a material delivery pipeline and a material delivery multi-way valve of the liquid intake device as a second cleaning output branch. Output branch; define the path formed along the reversing valve and cleaning pipeline of the air intake device to the cleaning multi-way valve as the first gas branch, define the path formed along the reversing valve and material delivery pipeline of the air intake device to the material delivery multi-way valve as the second gas branch; define the path formed along the reversing valve and cleaning pipeline of the feeding device to the cleaning multi-way valve as the first material branch, define the path formed along the reversing valve and material delivery pipeline of the feeding device to the material delivery multi-way valve as the second material branch; define the path formed from the material delivery multi-way valve to the end of the material distribution equipment as the material distribution main path;

[0018] The method comprises:

[0019] Q1, select the target material to be packaged, and based on the feeding device where the selected target material to be packaged is located, only connect the second material branch to the material distribution main road; start the material distribution equipment, so that the target material to be packaged is output along the second material branch to the end of the material distribution main road, so as to complete the packaging of the target material to be packaged;

[0020] F1, select the target cleaning liquid, and based on the feeding device where the selected target cleaning liquid is located, only connect the second cleaning output branch to the material distribution main road; start the material distribution equipment to make the target cleaning liquid output along the second cleaning output branch to the end of the material distribution main road to complete the cleaning of the material distribution main road;

[0021] F2, select the target gas, and based on the air intake device where the selected target gas is located, only connect the second gas branch and the material distribution main road; start the material distribution equipment to output the target gas along the second gas branch to the end of the material distribution main road to complete the emptying and drying of the material distribution main road. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 A schematic structural diagram of an in-situ cleaning and dispensing system provided in one embodiment of the present invention;

[0023] Figure 2 A schematic diagram of the structure of a material delivery multi-way valve provided in one embodiment of the present invention;

[0024] Figure 3 A schematic diagram of the structure of a material delivery multi-way valve provided in another embodiment of the present invention;

[0025] Figure 4 A schematic diagram of the three-dimensional structure of an in-situ cleaning and dispensing system provided in one embodiment of the present invention;

[0026] Figure 5 A cross-sectional view of a partial structure of an in-situ cleaning dispensing system is provided for one embodiment of the present invention;

[0027] Figure 6 A schematic diagram of the steps of an initialization method of an in-situ cleaning dispensing system provided by the present invention;

[0028] Figure 7 A schematic diagram of the steps of an initialization method of an in-situ cleaning dispensing system provided by the present invention;

[0029] Figure 8 A schematic diagram of some steps of an initialization method of an in-situ cleaning material distribution system provided by the present invention;

[0030] Fig. 9 A schematic diagram of some steps of an initialization method of an in-situ cleaning and dispensing system provided by the present invention;

[0031] Fig.10 A schematic diagram of some steps of an initialization method of an in-situ cleaning and dispensing system provided by the present invention;

[0032] Fig.11 A schematic diagram of the steps of a material dispensing method for an in-situ cleaning material dispensing system provided by the present invention;

[0033] Fig.12 A schematic diagram of the steps of a material dispensing method for an in-situ cleaning material dispensing system provided by the present invention;

[0034] Fig.13 A schematic diagram of the steps of a material dispensing method for an in-situ cleaning material dispensing system provided by the present invention.

[0035] 100, in-situ cleaning dispensing system; 10, feeding device group; 1001, feeding device; 101, liquid inlet device; 102, air inlet device; 103, feeding device; 11, reversing valve; 111, internal valve port; 112, cleaning valve port; 113, feeding valve port; 12, one-way valve; 13, filter; 14, storage container; 141, accommodating part; 142, blocking part; 15, feeding source; 20, cleaning pipe 1. Pipe group; 21. Cleaning pipeline; 30. Feed pipeline group; 31. Feed pipeline; 40. Feed multi-way valve; 41. Feed inlet; 42. Feed outlet; 43. Valve core; 44. Main body; 45. Feed branch; 46. Feed main; 50. Liquid separation multi-way head; 51. Branch flow channel; 511. Converging section; 512. Joint section; 513. Sealing end face; 52. Main flow channel; 60. Feeding equipment; 61. Liquid separation Pipeline; 601, sub-packaging liquid inlet; 602, sub-packaging liquid outlet; 62, delivery pump; 63, liquid dispensing joint; 90, liquid dispensing nozzle; 70, cleaning multi-way valve group; 71, T-type three-way valve; 701, main bypass channel; 702, branch bypass channel; 80, shell; 81, lower support shell; 811, avoidance port; 82, upper protective shell; 821, annular baffle; 822, cover; 88, first touch screen; 91, pipe Path organizing part; 911, accommodating card position; 92, first liquid contact part; 93, discharge pipe; 94, second liquid contact part; 95, collecting device; 951, storage part; 952, collecting pipe; 953, anti-return structure; 954, gas filter; 96, host computer; 97, second touch screen; 98, circuit control board; 200, initialization method of in-situ cleaning dispensing system; 300, dispensing method of in-situ cleaning dispensing system. DETAILED DESCRIPTION

[0036] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0037] It should be noted that when a component is referred to as being "connected to" another component, it may be directly connected to the other component or there may be a central component. When a component is considered to be "set on" another component, it may be directly set on the other component or there may be a central component at the same time. When a component is considered to be "fixed to" another component, it may be directly fixed to the other component or there may be a central component at the same time.

[0038] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "or / and" used herein includes any and all combinations of one or more related listed items.

[0039] When different reagents need to be packaged for use, it is very inconvenient to use different packaging equipment. However, when switching between the same packaging equipment, cross-contamination is likely to occur between the pipelines, making it difficult to keep them clean. In addition, contamination is likely to occur at the access valve port each time different reagents are switched. The overall packaging safety, efficiency, and convenience are all low.

[0040] Based on this, the present application provides an in-situ cleaning and dispensing system 100, which can clean the dispensing system structure in-situ, and switch different materials in-situ for feeding and dispensing. It should be noted that cleaning includes but is not limited to one or more of washing, sterilization, emptying, and drying. Furthermore, the in-situ cleaning and dispensing system 100 provided by the present application is used in the field of material dispensing, including but not limited to the dispensing of materials such as biological reagents, chemical reagents, food and beverages.

[0041] See also Figures 1 to 5 The in-situ cleaning and dispensing system 100 provided in the present application includes a feeding device group 10, a cleaning pipeline group 20, a cleaning multi-way valve group 70, a feeding pipeline group 30, a feeding multi-way valve 40 and a dispensing device 60;

[0042] The feeding device group 10 includes a plurality of feeding devices 1001, each of which includes a feeding source 15 and a reversing valve 11. The feeding source 15 of at least one feeding device 1001 is gas, the feeding source 15 of at least one feeding device 1001 is cleaning liquid, and the feeding source 15 of at least one feeding device 1001 is a material to be packaged; the reversing valve 11 has at least three valve ports, which are respectively defined as an inner valve port 111, a cleaning valve port 112, and a reversing valve port 113. and a feed valve port; wherein the inner valve port 111 is connected to the feed source 15, the cleaning valve port 112 is connected to one of the valve ports of the cleaning multi-way valve group 70 through a cleaning pipeline 21 in the cleaning pipeline group 20; the feed valve port is connected to one of the feed inlets 41 of the feed multi-way valve 40 through a feed pipeline 31 in the feed pipeline group 30; the material distribution device 60 is driven and connected to the feed outlet 42 of the feed multi-way valve 40 to provide a driving force for pumping out the feed source;

[0043] The cleaning multi-way valve group 70, the material feeding multi-way valve 40, and each reversing valve 11 can cooperate with each other to switch the provided material supply source 15 and the flow path of the material supply source 15 to complete in-situ cleaning, in-situ feeding, and in-situ material distribution.

[0044] The in-situ cleaning dispensing system 100 provided in the present application can use cleaning liquid to perform in-situ cleaning of any flow path and valve port through the coordination between pipelines and valves, and use gas to complete the emptying and drying of residual liquid, so that each flow path in the dispensing system remains clean, and cross-contamination problems after material storage, material access and material switching are effectively avoided, so that different materials to be packaged can be quickly switched and packaged in the same packaging pipeline system, thereby greatly improving the packaging efficiency, packaging convenience and packaging safety.

[0045] See also Figure 1 and Figure 4 In one embodiment, the reversing valve 11 is a three-way valve, that is, a three-position three-way valve. It is understood that in other embodiments, the reversing valve 11 may also be a four-way valve or other types of valve bodies, as long as the function of the in-situ cleaning and dispensing system 100 is not affected.

[0046] See also Figure 1 and Figure 4 In one embodiment, the cleaning multi-way valve group 70 includes a plurality of T-type three-way valves 71 arranged in series, and two valve ports of the plurality of T-type three-way valves 71 are connected in parallel and opposite to each other in sequence to form a main bypass channel 701, and the other valve ports of the plurality of T-type three-way valves 71 correspond to form a plurality of branch bypass channels 702. In other words, a plurality of branch bypass channels 702 are connected in parallel and aggregated to a main bypass channel 701, and each branch bypass channel 702 can be switched on and off with the aggregated main bypass channel 701. The pipeline flow channel configuration equivalent to the cleaning multi-way valve group 70 is composed of a plurality of T-type structure pipelines and a plurality of multi-way valves in parallel, and a separate valve is provided at each inlet and outlet to control the on and off of the main bypass channel 701 and the branch bypass channel 702. It can be understood that adjacent T-type three-way valves 71 are connected by connecting pipes.

[0047] Since the cleaning multi-way valve group 70 is an intermediate valve station connected to the cleaning pipeline 21 of each feeding device 1001 in the whole system, it is equivalent to a collection device for switching cleaning liquid and clean air. At the same time, during the initialization process of the in-situ cleaning and material distribution system, it is also necessary to use cleaning liquid to clean and sterilize the cleaning multi-way valve group 70. Therefore, it is necessary to clean the flow channel in the multi-way valve group 70 with a flow direction design so that there are no blind ends and cleaning dead corners when the cleaning liquid passes through. At the same time, after the cleaning is completed, a flow direction design is also required to ensure that the clean air can drain the cleaning liquid in the valve group of the cleaning pipeline 21, and there is also no blind end and dead corner. Therefore, when the cleaning multi-way valve group 70 is composed of multiple T-type three-way valves 71 connected in parallel, it is necessary to require the two ends of the cleaning multi-way valve group 70 in the horizontal direction, one end is used for the access of cleaning liquid (for example, ethanol), and the other end is used for the access of gas (for example, clean air), so that the cleaning liquid or gas can pass through all valve bodies, and blind ends and dead corners are not easy to appear.

[0048] Therefore, in one embodiment, a feed source 15 is configured as a feed device 1001 for gas and a feed source 15 is configured as a feed device 1001 for cleaning liquid, respectively, through the cleaning pipelines 21 connected to each other, and are horizontally connected from both sides to the two valve ports at both ends of the main bypass channel 701. In other words, when the cleaning multi-way valve group 70 is in the form of multiple parallel T-shaped structures, the T-shaped structures are required to be arranged in a positive direction, so that at least one cleaning liquid is horizontally connected from one end, at least one gas is horizontally connected from the other end, and all the materials to be distributed are connected from the lower end of the T-shaped structure, and the cleaning liquid and gas can flow through the entire main bypass channel 701 and both sides of the main bypass channel 701, and can also flow out from each branch bypass channel 702 through the main bypass channel 701, effectively avoiding the occurrence of cleaning dead corners and blind ends.

[0049] It is understood that in other embodiments, the cleaning multi-way valve group 70 may also be composed of other forms of parallel and / or series pipelines and different valves. For example, in one embodiment, the cleaning multi-way valve group 70 is composed of a multi-inlet single-outlet multi-way switching valve and a single-inlet multi-outlet multi-way switching valve in series. In this case, there is no restriction on the access position of the feeding device 1001 configured as a gas and the feeding device 1001 configured as a cleaning liquid.

[0050] See also Figure 1 and Figure 4 In one embodiment, the feed source 15 is configured as a gas feed device 1001, and further includes a one-way valve 12 and a filter 13. The feed source 15 is configured as a gas feed device 1001, and the reversing valve 11 of the gas feed device 1001 is an inverted T-type three-way valve, wherein the inner valve port 111 faces upward and is sequentially connected to the one-way valve 12, the filter 13 and the feed source 15. That is, the installation position relationship of the three-way valve, the one-way valve 12 and the filter 13 of the gas feed device 1001 requires that the filter 13 is on the one-way valve 12, the one-way valve 12 is on the three-way valve, and the three are installed vertically in series, and the three-way valve is installed in an inverted T shape.

[0051] With such an arrangement, the inverted T-type three-way valve can ensure that when the system is connected to the air intake device 102 for air supply, the cleaning liquid can also clean the inside of the three-way valve of the corresponding air supply feeding device 1001 through the cleaning pipeline, while ensuring that when the one-way valve 12 is switched to open the air intake, the cleaning liquid will not flow back into the air supply device 1001 for air supply.

[0052] In one embodiment, the feeding device 1001 in which the feeding source 15 is configured as gas further includes a storage container, which is connected to the side of the filter 13 away from the reversing valve 11 and is used to store the feeding source 15 configured as gas. In some embodiments, the gas may be clean air, and the air may not need to be stored in a storage container, but may be directly filtered through the filter 13 to become clean air and pass into the in-situ cleaning dispensing system 100. When the gas is nitrogen, helium, high-temperature steam or other gases, a storage container may be used for storage, so as to facilitate access and sterilization and cleaning.

[0053] See also Figure 1 and Figure 4 In one embodiment, the feeding device 1001 in which the feed source 15 is configured as a cleaning liquid or a material to be packaged further includes a storage container 14 and a filter 13. The storage container 14 is provided with a first hole and a second hole, wherein the first hole is connected to the inner valve port 111 of the reversing valve 11, and the second hole is connected to the filter 13. That is, when the feed source 15 is a liquid, a storage container 14 may be provided to store the feed source 15, and a hole for air intake is required to be provided so that the feed source 15 can be pumped out of the storage container 14 for packaging or use. The filter 13 is provided at the second hole to prevent the feed source 15 in the storage container 14 from being contaminated by the external environment.

[0054] Furthermore, when the cleaning liquid or the material to be packaged is volatile, the feed source is easily lost due to volatilization or pollutes the external environment after volatilization. Therefore, in some embodiments, the feed source 15 is configured as a feed device 1001 for the cleaning liquid or the material to be packaged, and further includes a one-way valve 12, and the second hole can be connected to the filter through the one-way valve 12 to reduce or avoid the risk of liquid loss or environmental pollution.

[0055] In one embodiment, the storage container 14 includes a receiving portion 141 and a blocking portion 142 connected to each other, and the first hole and the second hole are provided in the blocking portion 142; wherein the blocking portion 142, the one-way valve 12, the reversing valve 11 and the filter 13 are an integrated structure. It can be understood that the integrated structure is convenient for use, and is convenient for overall sterilization and cleaning.

[0056] It is understood that the gas includes but is not limited to one or more of air, nitrogen, helium, and high-temperature steam. The cleaning liquid includes but is not limited to one or more of bleach, acid and alkali solution, organic solvent, alcohol, water, and high-temperature steam.

[0057] It is understood that the use of a cleaning liquid with a bactericidal effect can simultaneously complete the cleaning and sterilization of the pipeline. The use of a volatile, residue-free cleaning liquid can facilitate rapid drying after cleaning. For example, the use of ethanol as a cleaning liquid can take into account the advantages of both sterilization and easy drying after cleaning.

[0058] See also Figure 1 , Figure 2 , Figure 4 and Figure 5 In one embodiment, the material feeding multi-way valve 40 is a multi-inlet and single-outlet multi-way switching valve. Specifically, the material feeding multi-way valve 40 includes a main body 44 and a valve core 43 movably connected to the main body 44. The main body 44 is provided with a plurality of material feeding branches 45 and a material feeding main path 46. By rotating the valve core 43, different material feeding branches 45 can be switched to be connected to the material feeding main path 46.

[0059] It can be understood that the end of each feed branch 45 away from the valve core 43 is the feed inlet 41 of the feed multi-way valve 40, and the end of the feed main line 46 away from the valve core 43 is the feed outlet 42 of the feed multi-way valve 40. The feed sources 15 of multiple feeding devices 1001 enter the feed multi-way valve 40 from different feed branches 45 respectively, and share the same feed main line 46 to output to the outside of the feed multi-way valve 40. Therefore, when switching the material to be packaged, at least the path from the output main line to the end of the feed distribution equipment 60 needs to be cleaned.

[0060] See also Figure 3 It can be understood that in other embodiments, the material delivery multi-way valve 40 can also be a multi-input and multi-output multi-way switching valve. That is, in other embodiments, the material delivery multi-way valve 40 can have multiple material delivery outlets 42. In this way, each material delivery outlet 42 can be connected to a material distribution device 60 to increase the number of portions of the material to be distributed each time according to demand.

[0061] It can be understood that in some embodiments, the reversing valve and the cleaning multi-way valve group can also be implemented as Figure 2 and Figure 3 In other words, as long as the functions of in-situ cleaning, in-situ feeding and in-situ dispensing of the in-situ cleaning and dispensing system can be realized, in other embodiments, the types and configurations of the reversing valve, the cleaning multi-way valve group and the feeding multi-way valve are not limited.

[0062] See also Figure 1 , Figure 4 and Figure 5 Furthermore, the in-situ cleaning material distribution system 100 further includes a liquid distribution multi-way head 50, and the material distribution device 60 is connected to a material delivery outlet 42 of the material delivery multi-way valve 40 through the liquid distribution multi-way head 50. The liquid distribution multi-way head 50 facilitates the uniform distribution of the material to be distributed flowing to the material delivery multi-way valve 40 to the material distribution device 60.

[0063] See also Figure 1 , Figure 4 and Figure 5The liquid-distributing multi-way head 50 includes a main flow channel 52 and a plurality of branch flow channels 51 connected to the same end of the main flow channel 52; one end of the main flow channel 52 away from the branch flow channel 51 is connected to the material delivery outlet 42 of the material delivery multi-way valve 40; the other ends of the plurality of branch flow channels 51 are respectively connected to a plurality of liquid dispensing inlets 601 of the material distributing device 60; wherein the plurality of branch flow channels 51 are symmetrically arranged along the central axis of the main flow channel 52 in an annular direction, and the central axis of each branch flow channel 51 has an angle with the central axis of the main flow channel 52, and the angle is a right angle or an acute angle. With such an arrangement, each branch flow channel 51 has equal resistance, which is convenient for even and stable material distribution.

[0064] Furthermore, the central axes of the multiple branch flow channels 51 intersect at the same point on the central axis of the main flow channel 52; and / or, the flow channel shapes of the multiple branch flow channels 51 are the same; and / or, the inner wall finish of the multiple branch flow channels 51 is the same; and / or, the flow channel lengths of the multiple branch flow channels 51 are equal; and / or, the inner diameters of the multiple branch flow channels 51 are equal. In this way, it is possible to further ensure that the resistance, flow velocity, and flow rate of each flow channel are equal, and further reduce the risk of uneven flow rate in each branch flow channel 51. In addition, the smooth inner wall of the flow channel and the smooth structural transition can further avoid the occurrence of cleaning dead corners.

[0065] See also Figure 5 Furthermore, along the gravity direction, the liquid-separating multi-way head 50 is installed above the material-feeding multi-way valve 40. In other words, the main flow channel 52 of the liquid-separating multi-way head 50 is at the bottom, and the branch flow channels 51 are evenly distributed and obliquely upward, and the flow direction of the liquid in the liquid-separating multi-way head 50 is upward or obliquely upward. In this way, the inlet is located in the middle of the bottom, and the design of the branches being symmetrical and evenly distributed obliquely upward can facilitate the smooth discharge of gas bubbles in the flow channel, avoid the accumulation of bubbles to form air chambers, and further avoid the formation of air chambers to cause uneven flow.

[0066] See also Figure 5 Further, in this embodiment, the feed inlet 41 and the feed outlet 42 of the feed multi-way valve 40 are both facing upward. In this way, it is convenient to discharge the bubbles in the feed multi-way valve 40 and to connect the pipeline with the feed inlet 41.

[0067] Exemplarily, the degree of the angle is defined as a, 20°≤a≤60°. In this way, the fluid flow is more convenient and the air bubbles in the flow channel are discharged.

[0068] See also Figure 4 and Figure 5In one embodiment, each branch flow channel 51 includes a converging section 511 and a joint section 512 which are coaxially arranged and connected to each other. The end of the converging section 511 away from the joint section 512 is connected to the main flow channel 52. The joint section 512 is used to connect to the material distribution device 60. The inner diameter of the joint section 512 is larger than the inner diameter of the converging section 511, so as to form a sealing end surface 513 at the junction of the joint section 512 and the converging section 511. The sealing end surface 513 is used to achieve a sealed connection with the material distribution device 60.

[0069] See also Figure 1 , Figure 4 and Figure 5 The material dispensing device 60 includes a delivery pump 62, a liquid dispensing pipeline 61 and a liquid dispensing joint 63. The delivery pump 62 has a plurality of dispensing liquid inlets 601 and a plurality of dispensing liquid outlets 602. The liquid dispensing joint 63 has a first plug-in end and a second plug-in end opposite to each other. The first plug-in end is plugged into the joint section 512, and the end face of the first plug-in end is face-to-face with the sealing end face 513. The second plug-in end is connected to one of the dispensing liquid inlets 601 through the liquid dispensing pipeline 61. It should be noted that the sealing end face 513 is an annular step surface, and the first plug-in end and the sealing end face 513 have the same diameter.

[0070] See also Figure 5 , further, the liquid separation joint 63 is threadedly connected to the liquid separation multi-way head 50. Specifically, the first plug end is provided with an external thread, the joint section 512 is provided with an internal thread, and the first plug end is threadedly connected to the joint section 512. In this way, the threaded connection can ensure the connection reliability, and the connection between the liquid separation joint 63 and the liquid separation multi-way head 50 adopts equal diameter end face to end face sealing, which is conducive to achieving no fluid dead zone and facilitating more thorough cleaning of the flow channel.

[0071] In one embodiment, the material dispensing device 60 further includes a liquid dispensing nozzle 90, which is installed at the dispensing outlet 602 or connected to the dispensing outlet 602 through a liquid dispensing pipe. It can be understood that when the liquid dispensing nozzle 90 is installed, the liquid dispensing nozzle 90 forms the end of the material dispensing device 60.

[0072] See also Figure 4 and Figure 5 In one embodiment, the in-situ cleaning material dispensing system 100 further includes a housing 80, in which at least the material feeding multi-way valve and the liquid dispensing multi-way head 50 are installed, and at least part of the housing 80 is a transparent housing, which is used to observe the pipe body connected to the material feeding multi-way valve 40 and the liquid dispensing multi-way head 50. In this way, it is convenient to observe each pipeline, the surrounding of the pipeline, and the flow state of the fluid inside the pipeline, and to find abnormal conditions in time.

[0073] See also Figure 4 and Figure 5In one embodiment, the housing 80 includes a lower supporting shell 81 and an upper protective shell 82 which are connected to each other, and the upper protective shell 82 is a transparent shell.

[0074] Furthermore, the lower support shell 81 includes a plurality of panels, which are spliced ​​by buckling up and down, and buckling in front and back. This can prevent the risk of external liquid entering the shell and causing malfunction. In addition, the cable interface of the material distribution device 60 adopts a waterproof or shielding design to prevent the risk of being splashed by liquid in a laboratory environment.

[0075] See also Figure 4 and Figure 5 It should be noted that at least the material delivery inlet 41 of the material delivery multi-way valve 40 needs to be located in the upper protective shell 82, so as to facilitate the observation of the connection of the pipeline and the flow of the fluid in the pipeline.

[0076] The upper protective shell 82 includes an annular baffle 821 and a cover body 822 . The cover body 822 is disposed on the top of the annular baffle 821 and circumferentially blocks a portion of the side wall of the annular baffle 821 .

[0077] See also Figure 4 and Figure 5 In one embodiment, the in-situ cleaning and distributing device further includes at least one pipeline organizing member 91, which is installed on the housing 80, and at least one side of the pipeline organizing member 91 has a plurality of accommodating positions 911 for accommodating the pipe body. In this way, the cleaning pipeline, the material delivery pipeline 31 and the distributing pipeline can be fixed by the pipeline organizing member 91. The pipeline organizing member 91 can support and organize the pipeline, enhance the stability of the pipeline installation, and facilitate clearer distinction and observation of the status of each pipeline.

[0078] See also Figure 4 and Figure 5 In one embodiment, the pipeline arrangement member 91 is detachably mounted on the housing 80. Thus, after the pipeline arrangement member 91 is removed from the housing 80, it is easier to operate and arrange or remove the pipelines to be arranged.

[0079] In one embodiment, at least one side of the pipeline organizer 91 is provided with a mounting slot, and the pipeline organizer 91 is mounted on the top edge of the annular baffle 821 through the mounting slot and is located between the cover 822 and the annular baffle 821. In this way, it is convenient to centrally observe the connection status of each pipeline and the flow status of the fluid in each pipeline.

[0080] It is understood that in other embodiments, the pipe arrangement member 91 can also be fixed to the housing 80 in other ways. For example, a mounting protrusion is provided on at least one side of the pipe arrangement member 91, and a snap-fit ​​hole is provided on the protective shell, and the pipe arrangement member 91 is mounted on the protective shell through the snap-fitting of the mounting protrusion and the snap-fit ​​hole. It is understood that in other embodiments, the pipe arrangement member 91 can also be bonded to the housing 80.

[0081] See also Figure 4 and Figure 5 The in-situ cleaning material distribution system 100 further includes a circuit control board 98 and a first touch screen 88 mounted on the housing 80, and the circuit control board 98 is electrically connected to the material feeding multi-way valve 40 and the first touch screen 88. In this way, the on-off of the flow channel in the material feeding multi-way valve 40 can be controlled separately through the first touch screen 88.

[0082] Furthermore, the in-situ cleaning and dispensing system 100 also includes a host computer 96 and a second touch screen 97, wherein the host computer 96 is at least electrically connected to the second touch screen 97, the feeding multi-way valve 40, the dispensing device 60 and the circuit control board 98, and is used to control the opening and closing of each valve port and the start and stop of the dispensing device. It can be understood that the cleaning multi-way valve group 70 and the reversing valve 11 can be an electric valve or a manual valve. When the cleaning multi-way valve group 70 and the reversing valve 11 are electric valves, they can also be electrically connected to the host computer 96 and uniformly controlled by the host computer 96.

[0083] See also Figure 4 and Figure 5 In one embodiment, the in-situ cleaning and dispensing system 100 further includes a first liquid receiving member 92 , which is circumferentially arranged around the material delivery multi-way valve 40 and the liquid dispensing multi-way head 50 , and is located below the material delivery inlet 41 of the material delivery multi-way valve 40 .

[0084] Furthermore, the first liquid receiving member 92 may be configured as an annular liquid collecting groove opened on the top of the lower supporting shell 81 , or may be configured as an annular liquid collecting plate independently installed on the top of the lower supporting shell 81 .

[0085] See also Figure 4 and Figure 5 Furthermore, the in-situ cleaning dispensing system 100 also includes a liquid discharge pipe 93 , which is connected to the first liquid receiving member 92 and is used to discharge the liquid collected by the first liquid receiving member 92 .

[0086] In other words, a liquid collecting structure is provided at the bottom of the material inlet 41 and the material outlet 42 of the material feeding multi-way valve 40 and around the liquid separation multi-way head 50, for collecting waste liquid from leakage, condensation and the like. The liquid collecting structure is connected to a drain pipe 93, which can discharge the waste liquid in the liquid collecting structure to prevent it from entering the interior of the machine body.

[0087] The material distributing device 60 further includes a second liquid receiving member 94 , which is located below the end of the material distributing device 60 , and can be located below the distributing liquid outlet 602 and / or the distributing nozzle, for collecting waste liquid that may seep out from the end of the material distributing device 60 .

[0088] In one embodiment, the first liquid contacting member 92 is connected to the second liquid contacting member 94 through the liquid discharge pipe 93 , that is, the waste liquid of the first liquid contacting member 92 can be collected in the second liquid contacting member 94 and then discharged centrally through the second liquid contacting member 94 .

[0089] See also Figure 1 , Figure 4 and Figure 5 In one embodiment, the in-situ cleaning dispensing system 100 also includes a collecting device 95, which includes a storage element 951 and a collecting tube 952. The collecting tube 952 has an input port and an output port, the output port is connected to the storage element 951, and the input port is connected to the first liquid contacting element 92 and / or the second liquid contacting element 94; the waste liquid enters the collecting tube 952 from the input port and enters the storage element 951 through the output port.

[0090] See also Figure 1 , Figure 4 and Figure 5 Furthermore, the collecting device 95 also includes an anti-backflow structure 953, which is arranged between the input port and the output port, and is used to prevent the waste liquid entering the storage element 951 from flowing back to the output port.

[0091] In one embodiment, the anti-return structure 953 is configured as a part of the tube body of the collection tube 952, and the part of the tube body is bent in a U shape to form a liquid-sealed buffer chamber into which the barrier liquid can be injected. It can be understood that the barrier liquid can be provided by a supply source 15 of one of the supply devices 1001.

[0092] See also Figure 1 It is understood that the anti-return structure 953 can also be configured as a one-way valve 12 or a float valve, as long as it can prevent the waste liquid from flowing back.

[0093] See also Figure 1 , Figure 4 and Figure 5 Furthermore, the storage element 951 is provided with an exhaust port, and a gas filter element 954 is provided at the exhaust port. The gas filter element 954 is used to filter the gas volatilized from the waste liquid to avoid the risk of the waste liquid polluting the air.

[0094] In one embodiment, the gas filter 954 includes an activated carbon filter 13. It is understood that in other embodiments, the type of the gas filter 954 can be selected according to demand, and can also be a high-efficiency filter 13, which can be used for filtering toxic substances and microorganisms such as bacteria and spores.

[0095] The storage element 951 includes a container bottle and a container cover connected to each other, and the exhaust port is arranged on the container cover; the gas filter element 954 and the container cover are an integral structure, so that it is convenient to use and clean and sterilize the whole.

[0096] See also Figure 1By way of example, the specific structure of the in-situ cleaning and dispensing system 100 in one embodiment is specifically described by taking the feeding device group 10 provided with 10 feeding devices 1001 as an example.

[0097] See also Figure 1 For ease of understanding, the feeding device 1001 whose feeding source 15 is gas is defined as the air inlet device 102, the feeding device 1001 whose feeding source 15 is cleaning liquid is defined as the liquid inlet device 101, and the other feeding devices 1001 whose feeding sources 15 are materials to be packaged are all defined as the feeding devices 103. The air inlet device 102 is numbered ⑩, the liquid inlet device 101 is numbered ⑨, and the other 8 feeding devices 1001 are numbered ①-⑧ respectively.

[0098] The cleaning multi-way valve group 70 includes 8 T-type three-way valves 71 arranged in a forward direction and connected in sequence. The 8 lower valve ports of the 8 T-type three-way valves 71 form 8 branch bypass channels 702, and are respectively connected to the cleaning valve ports 112 of the 8 feeding devices 1001 through 8 cleaning pipelines 21. The parallel valve ports of the 8 T-type three-way valves 71 are connected in sequence to form the main bypass channel 701, and the valve ports of the two T-type three-way valves 71 on both sides that are away from each other are respectively connected to the cleaning valve ports 112 of the liquid inlet device 101 and the cleaning valve ports 112 of the air inlet device 102 through two cleaning pipelines 21. Figure 1 , the eight T-type three-way valves 71 of the cleaning multi-way valve group 70 are numbered V1-V8 respectively. Among them, along the main bypass channel 701, the valve port of V8 away from V1 is connected to the cleaning valve port 112 of the liquid inlet device 101⑨ through the cleaning pipeline 21, the valve port of V1 away from V8 is connected to the cleaning valve port 112 of the air inlet device 102⑩ through the cleaning pipeline 21, and the lower valve ports of V1 to V8 are respectively connected to the cleaning valve ports of the feeding device 103①-103⑧ in sequence through a cleaning pipeline.

[0099] Furthermore, the feed multi-way valve 40 of the in-situ cleaning feed dispensing system 100 includes 10 feed inlets 41 and 1 feed outlet 42. The feed valve ports of 10 feeding devices 1001 are respectively connected to the 10 feed inlets 41 through 10 feed pipelines 31; the feed outlet 42 is connected to the feed dispensing equipment 60 through a liquid dispensing multi-way head 50, wherein the liquid dispensing multi-way head 50 has 1 main flow channel 52 and 8 branch flow channels 51, that is, 1 liquid dispensing inlet and 8 liquid dispensing outlets, the liquid dispensing inlet is connected to the feed outlet 42, the 8 liquid dispensing outlets are respectively connected to the 8 material dispensing liquid inlets of the feed dispensing equipment 60 through 8 liquid dispensing pipelines 61, and the 8 material dispensing liquid outlets of the feed dispensing equipment 60 are respectively connected to the 8 liquid dispensing nozzles 90 through 8 liquid dispensing pipelines 61.

[0100] See also Figure 1Furthermore, the distributing device 60 is provided with a second liquid contacting part 94, the input port of the collecting pipe 952 of the collecting device 95 is connected to the second liquid contacting part 94, and the anti-return structure 953 is configured as a one-way valve 12 arranged between the input port and the output port of the collecting pipe 952.

[0101] Furthermore, the cleaning liquid in the liquid inlet device 101⑨ is configured as ethanol, and the gas in the air inlet device 102⑩ is configured as air. It should be noted that the air entering the in-situ cleaning dispensing system 100 is clean air, which can be clean air directly introduced, or it can be clean air formed by filtering natural air through the filter 13 of the air inlet device 102. The materials to be packaged in the feeding devices 103①-⑧ are different biological reagents. In the present embodiment, the cleaning liquid is specifically a 75% ethanol solution. It will be understood that in other embodiments, the concentration of ethanol is not limited.

[0102] It should be noted that before the in-situ cleaning dispensing device is used for dispensing, initialization treatment needs to be completed to avoid contamination of the biological reagents to be packaged. Initialization treatment refers to using the ethanol in the liquid inlet device 101⑨ to clean and sterilize the flow path and valve body to which the fluid can flow in the entire in-situ cleaning dispensing system 100, and using the clean gas in the air inlet device 102 to empty and dry the residual ethanol in the flow path and valve body after cleaning and sterilization. After the initialization is completed, the flow path required for the dispensing of the target biological reagent can be connected by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, and the liquid dispensing pump of the dispensing device 60 is started in the positive direction to dispense once or multiple times as required.

[0103] It should be noted that when the next target biological reagent to be packaged is different from the last biological reagent that has been packaged, the flow path from the feeding multi-way valve 40 to the end of the dispensing device 60 needs to be cleaned and sterilized by ethanol and clean air and emptied and dried. It can be understood that the cleaning and sterilization process and the emptying and drying process can be repeated as needed to ensure thorough cleaning.

[0104] In addition, it should be noted that when there is a need to recycle the liquid, the liquid separation pump of the material separation device 60 can also be reversely started. For example, when the biological reagent is very precious and expensive, the liquid separation pump can also be reversely started after packaging to make the residual biological reagent in the corresponding flow path flow back to the storage container 14 of the original feeding device 1001 to reduce loss and save costs.

[0105] It is further understood that multiple cleaning liquids and gases can also be provided. For example, the feed source 15 in the feeding device ⑨ can be configured as ethanol, and the feed source 15 in the feeding device ⑧ can be configured as distilled water. After the pipeline is cleaned and sterilized using the ethanol in the feeding device ⑨, it can be cleaned again using the distilled water in the feeding device ⑧, and then the residual liquid in the flow path can be emptied and dried using clean air. In other words, the cleaning strategy and the emptying strategy can be designed according to the cleaning difficulty and requirements of different reagents. When the reagent cleaning difficulty is high, it can be repeatedly switched between cleaning with the cleaning liquid and emptying with the gas to achieve the purpose of cleaning.

[0106] In summary, the in-situ cleaning and dispensing system 100 provided in the present application, in which the cleaning multi-way valve group 70 and the material delivery multi-way valve 40 serve as two intermediate valve stations to cooperate with the reversing valve 11 of each feeding device 1001, and can open and close the flow of any flow path and switch the output of any feeding source 15 according to needs, to complete the in-situ cleaning, in-situ feeding and in-situ dispensing processes, effectively solve the problems of cross-contamination during material storage, material access and material switching, and greatly improve the packaging efficiency, packaging convenience and packaging safety.

[0107] See also Figure 5 The present invention further provides a liquid-separating multi-way head 50, which includes a main flow channel 52 and a plurality of branch flow channels 51, wherein one end of the plurality of branch flow channels 51 is connected to the same end of the main flow channel 52;

[0108] Multiple branch channels 51 are symmetrically arranged along the central axis of the main channel 52, and each branch channel 51 has an angle with the central axis of the main channel 52, which is a right angle or an acute angle. In this way, each branch channel 51 has equal resistance, which facilitates uniform and stable liquid separation.

[0109] Furthermore, the central axes of the multiple branch flow channels 51 intersect at the same point on the central axis of the main flow channel 52; and / or, the flow channel shapes of the multiple branch flow channels 51 are the same; and / or, the inner wall finish of the multiple branch flow channels 51 is the same; and / or, the flow channel lengths of the multiple branch flow channels 51 are equal; and / or, the inner diameters of the multiple branch flow channels 51 are equal. In this way, it is possible to further ensure that the resistance, flow velocity, and flow rate of each flow channel are equal, and further reduce the risk of uneven flow rate in each branch flow channel 51. In addition, the smooth inner wall of the flow channel and the smooth structural transition can further avoid the occurrence of cleaning dead corners.

[0110] Exemplarily, the degree of the angle is defined as a, 20°≤a≤60°. In this way, the air bubbles in the flow channel are discharged while the fluid flow is facilitated.

[0111] In one embodiment, each branch flow channel 51 includes a confluence section 511 and a joint section 512 that are coaxially arranged and interconnected, and one end of the confluence section 511 away from the joint section 512 is connected to the main flow channel 52, and the joint section 512 is used to connect the material distribution device 60; the inner diameter of the joint section 512 is larger than the inner diameter of the confluence section 511, so as to form a sealing end face 513 at the junction of the joint section 512 and the confluence section 511. The sealing end face 513 is used to be sealed and connected with the external component. In this way, the external component can achieve equal diameter end-to-end sealing between the sealing end face 513 and the liquid separation multi-way head 50, which is conducive to achieving no fluid dead zone, avoiding liquid accumulation and incomplete cleaning.

[0112] See also Figure 5 Furthermore, the joint section 512 is provided with an internal thread. Thus, the joint section 512 can be threadedly connected with the external component, thereby increasing the reliability of connection and sealing.

[0113] Furthermore, the liquid dispensing multi-channel head 50 includes but is not limited to PTFE parts, PEEK parts, nylon parts, polypropylene parts, and 316L stainless steel parts.

[0114] See also Figure 1 or Figure 4 The present invention also provides a collecting device 95, including a storage element 951 and a collecting tube 952, wherein the collecting tube 952 has an input port and an output port, wherein the output port is connected to the storage element 951, and the object to be collected enters the collecting tube 952 from the input port and enters the storage element 951 through the output port; wherein an anti-return structure 953 is further provided between the input port and the output port, and the anti-return structure 953 is used to prevent the object to be collected that enters the storage element 951 from flowing back to the output port.

[0115] In one embodiment, the anti-return structure 953 is configured as a part of the tube body of the collection tube 952, and the part of the tube body is bent in a U-shape to form a liquid-sealed buffer chamber into which a barrier liquid can be injected. In this way, when the collected material is a gas or a volatile liquid, the loss of the collected material due to the return flow can be effectively avoided, and the pollution problem caused by the return flow can be avoided.

[0116] Furthermore, the collecting device 95 is also provided with a liquid sealing structure, which is arranged between the input port and the liquid sealing buffer chamber and is used to inject the barrier liquid into the liquid sealing buffer chamber.

[0117] In one embodiment, the anti-return structure 953 is configured as a one-way valve or a floating valve. It is understood that in other embodiments, the anti-return structure 953 can also be configured as other types of valve bodies that can play a blocking role.

[0118] In one embodiment, the storage element 951 is provided with an exhaust port, and a gas filter element 954 is provided at the exhaust port.

[0119] In one embodiment, the gas filter 954 includes an activated carbon filter 13 .

[0120] In one embodiment, the storage element 951 includes a container bottle and a container cover that are connected to each other, and the exhaust port is provided on the container cover; the gas filter element 954 is an integral structure with the container cover.

[0121] Furthermore, the storage element 951, the one-way valve 12, and the filter element are all high-temperature resistant elements, and specific materials include but are not limited to PTFE, PEEK, and 316L stainless steel.

[0122] See also Figure 6 The present invention further provides an initialization method 200 for an in-situ cleaning dispensing system, comprising the above-mentioned in-situ cleaning dispensing system, defining a feeding device whose feeding source 15 is gas as an air inlet device 102, defining a feeding device whose feeding source 15 is cleaning liquid as a liquid inlet device 101, and defining a feeding device whose feeding source 15 is a material to be dispensed as a feeding device 103; the method comprises:

[0123] S0, pre-sterilize the liquid inlet device 101, the air inlet device 102 and the feed device 103;

[0124] S1, by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, a cleaning liquid is provided and the flow path of the cleaning liquid is switched, so that the cleaning liquid of the liquid inlet device 101 performs initial cleaning on the cleaning pipeline 21 and the material delivery pipeline 31 connected to the air inlet device 102;

[0125] S2, by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, gas is provided and the flow path of the gas is switched, the cleaning liquid in the cleaning pipeline 21 and / or the material delivery pipeline 31 connected to the air intake device 102 is emptied by the gas of the air intake device 102, and the cleaning pipeline 21 and / or the material delivery pipeline 31 connected to the air intake device 102 is dried;

[0126] S3, by cooperating with the cleaning multi-way valve group 70, the feeding multi-way valve 40 and each reversing valve 11, a cleaning liquid is provided and the flow path of the cleaning liquid is switched, so that the cleaning liquid of the liquid inlet device 101 performs initial cleaning on the cleaning pipeline 21 and the feeding pipeline 31 connected to the feeding device 103;

[0127] S4, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and the various reversing valves 11, gas is provided and the gas flow path is switched, and the gas from the air intake device 102 is used to empty the cleaning liquid in the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103, and the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103 are dried.

[0128] It should be noted that the cleaning multi-way valve group 70 and the material delivery multi-way valve 40 have also completed the initial cleaning, emptying and drying processes in each cleaning pipeline and material delivery pipeline, and are both clean devices.

[0129] It is further understood that the steps of cleaning with cleaning fluid, draining the cleaning fluid, and drying the pipeline can be repeated according to the cleaning difficulty and cleaning requirements until the cleanliness requirements are met. It should be emphasized that cleanliness can include sterility measurement parameters.

[0130] See also Figure 7 In some embodiments, the initialization method further comprises the following steps after step S2 or step S4:

[0131] S5, by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, a cleaning liquid is provided and the flow path of the cleaning liquid is switched, so that the cleaning liquid of the liquid inlet device 101 performs initial cleaning on the material delivery pipeline 31 and / or the cleaning pipeline 21 connected to the liquid inlet device 101;

[0132] S6, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and the various reversing valves 11, gas is provided and the gas flow path is switched, and the gas of the air intake device 102 is used to empty the cleaning liquid in the material delivery pipeline 31 and the cleaning pipeline 21 connected to the liquid inlet device 101, and the cleaning pipeline 21 and the material delivery pipeline 31 connected to the liquid inlet device 101 are dried.

[0133] See also Figure 8 In one embodiment, the path formed by the material supply source 15, the reversing valve 11, the cleaning pipeline 21 and the cleaning multi-way valve of the liquid inlet device 101 is defined as the first cleaning output branch, and the path formed by the material supply source 15, the reversing valve 11, the material delivery pipeline 31 and the material delivery multi-way valve 40 of the liquid inlet device 101 is defined as the second cleaning output branch; the path formed by the reversing valve 11, the cleaning pipeline 21 and the cleaning multi-way valve of the gas inlet device 102 is defined as the first gas branch, and the path formed by the reversing valve 11, the cleaning pipeline 21 and the cleaning multi-way valve of the gas inlet device 102 is defined as the second gas branch. The path formed by the reversing valve 11 and the material delivery pipeline 31 of the gas device 102 to the material delivery multi-way valve 40 is defined as the second gas branch; the path formed by the reversing valve 11 and the cleaning pipeline 21 of the feeding device 103 to the cleaning multi-way valve is defined as the first material branch, and the path formed by the reversing valve 11 and the material delivery pipeline 31 of the feeding device 103 to the material delivery multi-way valve 40 is defined as the second material branch; the path formed by the material delivery multi-way valve 40 to the end of the material distribution device 60 is defined as the material distribution main path;

[0134] S1 includes the steps:

[0135] S11, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, the first cleaning output branch, the first gas branch, the second gas branch and the material distribution main road are connected; the material distribution device 60 is started, so that the cleaning liquid of the liquid inlet device 101 is output along the first cleaning output branch to the end of the material distribution main road, and the initial cleaning of the cleaning pipeline 21 and the material delivery pipeline 31 connected to the gas inlet device 102 is completed, and the material distribution device 60 is closed;

[0136] S2 includes the steps:

[0137] S21, by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, the second gas branch and the material distribution main road are connected; the material distribution device 60 is started to output the gas in the air intake device 102 along the second gas branch to the end of the material distribution main road, so that the cleaning liquid in the material delivery pipeline 31 connected to the air intake device 102 is emptied by the gas of the air intake device 102, and the material delivery pipeline 31 connected to the air intake device 102 is dried, and the material distribution device 60 is closed;

[0138] See also Fig. 9 In one embodiment, S3 comprises the steps of:

[0139] S31, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, the first cleaning output branch, the first material branch, the second material branch and the material distribution main road are connected; the material distribution device 60 is started to output the cleaning liquid of the liquid inlet device 101 along the first cleaning output branch to the end of the material distribution main road, and the initial cleaning of the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103 is completed, and the material distribution device 60 is closed;

[0140] S4 includes the steps:

[0141] S41, connect the first gas branch, the first material branch, the second material branch to the material distribution main road through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and the various reversing valves 11; start the material distribution equipment 60, so that the gas of the air intake device 102 is output along the first gas branch to the end of the material distribution main road, so as to use the gas of the air intake device 102 to empty the cleaning liquid in the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103, and dry the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103, and close the material distribution equipment 60.

[0142] See also Fig.10 In one embodiment, S5 comprises the steps of:

[0143] S51, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, the second cleaning output branch is connected to the material distribution main road; the material distribution device 60 is started, so that the cleaning liquid of the liquid inlet device 101 is output along the second cleaning output branch to the end of the material distribution main road, so that the cleaning liquid of the liquid inlet device 101 performs initial cleaning on the material delivery pipeline 31 connected to the liquid inlet device 101;

[0144] S6 comprises the steps of:

[0145] S61, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and the various reversing valves 11, the first gas branch, the first cleaning output branch, the second cleaning output branch are connected to the material distribution main line; the material distribution equipment 60 is started, and the gas of the air intake device 102 is used to empty the cleaning liquid in the material delivery pipeline 31 and the cleaning pipeline 21 connected to the liquid inlet device 101, and the cleaning pipeline 21 and the material delivery pipeline 31 connected to the liquid inlet device 101 are dried.

[0146] It should be noted that when the flow path of the above-mentioned path is connected through the cooperation of the cleaning multi-way valve group 70, the material feeding multi-way valve 40 and the various reversing valves 11, it means that all other flow paths except this path are blocked, and the gas or cleaning liquid can only flow in this path.

[0147] It should be further explained that each step can be repeated as needed, in other words, it can be cleaned, emptied, and dried multiple times. Specific cleaning strategies, emptying strategies, and drying strategies can be designed and operated according to the difficulty of cleaning the reagents and the degree of dirtiness of the pipelines. They are not listed here one by one.

[0148] Further, in one embodiment, the feeding device in which the feeding source 15 is configured as a gas further includes a one-way valve 12 and a filter 13, and the reversing valve 11 in which the feeding source 15 is configured as a gas feeding device is a three-way valve arranged in an inverted T shape, wherein the inner valve port 111 faces upward and is sequentially connected to the one-way valve 12, the filter 13 and the feeding source 15; the feeding device in which the feeding source 15 is configured as a cleaning liquid or a material to be packaged further includes a storage container 14, a one-way valve 12 and a filter 13, and the storage container 14 is provided with a first hole and a second hole, wherein the first hole is connected to the inner valve port 111 of the reversing valve 11, and the second hole is sequentially connected to the one-way valve 12 and the filter 13;

[0149] Step S0 includes the steps of:

[0150] S00, sterilize the three-way valve, storage container, one-way valve 12, and filter 13 of the liquid inlet device 101 under high pressure and high temperature, and put the supply source 15 configured as a cleaning liquid into the sterilized storage container under a sterile environment to obtain a pre-sterilized liquid inlet device 101; or, sterilize the three-way valve, storage container with cleaning liquid, one-way valve 12, and filter 13 of the liquid inlet device 101 under high pressure and high temperature to obtain a pre-sterilized liquid inlet device 101;

[0151] S01, the three-way valve, the one-way valve 12, and the filter 13 of the air intake device 102 are sterilized under high pressure and high temperature, and connected to a gas supply source configured as clean gas to obtain a pre-sterilized air intake device 102; or, the air intake device 102 also includes a storage container, which is connected to a side of the filter 13 away from the three-way valve and is used to store a supply source 15; the three-way valve of the air intake device 102, the storage container with the material to be packaged, the one-way valve 12, and the filter 13 are sterilized under high pressure and high temperature to obtain a pre-sterilized air intake device 102;

[0152] S02, the three-way valve, storage container, one-way valve 12, and filter 13 of the feeding device 103 are sterilized under high pressure and high temperature, and the materials to be packaged are loaded into the sterilized storage container under a sterile environment to complete the pre-sterilized feeding device 103; or, the three-way valve, storage container with materials to be packaged, one-way valve 12, and filter 13 of the feeding device 103 are sterilized under high pressure and high temperature to obtain a pre-sterilized feeding device 103.

[0153] It should be noted that step S00, step S01, and step S02 may be performed together or separately.

[0154] In one embodiment, S0 comprises the steps of:

[0155] S03, putting the liquid inlet device 101, the air inlet device 102 and the material feeding device 103 into a high pressure sterilizer for sterilization;

[0156] S04, loading the cleaning liquid into the storage container 14 of the sterilized liquid inlet device 101 under a sterile operating environment; loading the material to be packaged into the storage container 14 of the sterilized material feeding device 103 under a sterile operating environment;

[0157] Further, in one embodiment, the reversing valve 11 is a three-way valve; the cleaning multi-way valve group 70 includes a plurality of T-type three-way valves 71 arranged in series, two valve ports of the plurality of T-type three-way valves 71 are connected in parallel and opposite to each other in sequence to form a main bypass channel 701, and the other valve ports of the plurality of T-type three-way valves 71 correspond to form a plurality of branch bypass channels 702; wherein, a feed source 15 configured as a gas feed device and a feed source 15 configured as a cleaning liquid feed device are respectively connected horizontally from both sides to the two valve ports at both ends of the main bypass channel 701 through the cleaning pipeline 21;

[0158] S11 comprises the steps of:

[0159] S111, connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the liquid inlet device 101, and connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the air inlet device 102;

[0160] S112, connecting the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the air inlet device 102 to the valve ports connected to the cleaning multi-way valve group 70 respectively;

[0161] S113, connecting the material delivery pipelines 31 correspondingly connected to the liquid inlet device 101 and the air inlet device 102 to the two material delivery inlets 41 of the material delivery multi-way valve 40 respectively;

[0162] S114, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the inner valve port 111;

[0163] S115, switching the three-way valve of the air intake device 102 so that the cleaning valve port 112 is connected to the feed valve port 113;

[0164] S116, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the air inlet device 102;

[0165] S117, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the air intake device 102;

[0166] S118, start the material distribution device 60, so that the cleaning liquid passes through the three-way valve of the liquid inlet device 101, the cleaning pipeline 21 corresponding to the liquid inlet device 101, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the air inlet device 102, the three-way valve of the air inlet device 102, the material delivery pipeline 31 corresponding to the air inlet device 102, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and completes the cleaning and sterilization of the cleaning pipeline connected to the air inlet device 102 and the material delivery pipeline 31;

[0167] In one embodiment, S21 includes the steps of:

[0168] S211, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0169] S212, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the material delivery pipeline 31 corresponding to the air intake device 102, the material delivery multi-way valve 40 and the end of the material distribution device 60, and completes the discharge of the residual cleaning liquid and the pipeline drying;

[0170] S213, closing the material distribution device 60, completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the air intake device 102;

[0171] In one embodiment, S31 includes the steps of:

[0172] S311, connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the liquid inlet device 101, and connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the feeding device 103;

[0173] S312, connecting the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the material feed device 103 to the valve ports connected to the cleaning multi-way valve group 70 respectively;

[0174] S313, connecting the material delivery pipelines 31 correspondingly connected to the liquid inlet device 101 and the material feeding device 103 to the two material delivery inlets 41 of the material delivery multi-way valve 40 respectively;

[0175] S314, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the inner valve port 111;

[0176] S315, switching the three-way valve of the feeding device 103 so that the cleaning valve port 112 is connected to the feeding valve port 113;

[0177] S316, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipeline 21 corresponding to the liquid inlet device 101 and the material feeding device 103;

[0178] S317, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the feeding device 103;

[0179] S318, start the material distribution device 60, so that the cleaning liquid passes through the three-way valve of the liquid inlet device 101, the cleaning pipeline 21 corresponding to the liquid inlet device 101, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the feeding device 103, the three-way valve of the feeding device 103, the material delivery pipeline 31 corresponding to the feeding device 103, and the material delivery multi-way valve 40 to the end of the material distribution device 60, completing the cleaning and sterilization of the cleaning pipeline connected to the feeding device 103 and the material delivery pipeline 31;

[0180] In one embodiment, S41 includes the steps of:

[0181] S411, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the cleaning valve port 112;

[0182] S412, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the air intake device 102 and the feed device 103;

[0183] S413, switching the three-way valve of the feeding device 103 so that the cleaning valve port 112 is connected to the feeding valve port 113;

[0184] S414, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the feeding device 103;

[0185] S415, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the cleaning pipeline corresponding to the air intake device 102, the main bypass channel 701 of the cleaning multi-way valve group 70, the branch bypass channel 702 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the feeding device 103, the three-way valve of the feeding device 103, the material delivery pipeline 31 corresponding to the feeding device 103, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and the residual liquid of the cleaning liquid is discharged and the pipeline is dried;

[0186] S415, closing the material distribution device 60, completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the feeding device 103;

[0187] In one embodiment, S51 includes the steps of:

[0188] S511, switching the three-way valve of the liquid inlet device 101 so that the inner valve port 111 is connected to the feed valve port 113;

[0189] S512, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the liquid inlet device 101;

[0190] S513, start the material distribution device 60 to complete the cleaning and sterilization of the material delivery pipeline 31 connected to the liquid inlet device 101;

[0191] In one embodiment, S61 includes the steps of:

[0192] S611, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0193] S612, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the air inlet device 102 and the liquid inlet device 101;

[0194] S613, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the feed valve port 113;

[0195] S614, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the liquid inlet device 101;

[0196] S615, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the cleaning pipeline corresponding to the air intake device 102, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the liquid intake device 101, the three-way valve of the liquid intake device 101, the material delivery pipeline 31 corresponding to the liquid intake device 101, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and the residual liquid of the cleaning liquid is discharged and the pipeline is dried;

[0197] S616, closing the material distribution device 60, and completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the liquid inlet device 101.

[0198] It can be understood that when the cleaning pipeline connected to the air intake device 102 and the material delivery pipeline 31 are cleaned and sterilized, the cleaning pipeline connected to the liquid intake device 101 has been cleaned and sterilized. Therefore, the cleaning pipeline connected to the liquid intake device 101 can be sterilized repeatedly in subsequent steps or no longer.

[0199] In a specific embodiment, the initialization method comprises the steps of:

[0200] S0, pre-sterilize the liquid inlet device 101, the air inlet device 102 and the feed device 103;

[0201] S111, connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the liquid inlet device 101, and connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the air inlet device 102;

[0202] S112, connecting the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the air inlet device 102 to the valve ports connected to the cleaning multi-way valve group 70 respectively;

[0203] S113, connecting the material delivery pipelines 31 correspondingly connected to the liquid inlet device 101 and the air inlet device 102 to the two material delivery inlets 41 of the material delivery multi-way valve 40 respectively;

[0204] S114, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the inner valve port 111;

[0205] S115, switching the three-way valve of the air intake device 102 so that the cleaning valve port 112 is connected to the feed valve port 113;

[0206] S116, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the air inlet device 102;

[0207] S117, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the air intake device 102;

[0208] S118, start the material distribution device 60, so that the cleaning liquid passes through the three-way valve of the liquid inlet device 101, the cleaning pipeline 21 corresponding to the liquid inlet device 101, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the air inlet device 102, the three-way valve of the air inlet device 102, the material delivery pipeline 31 corresponding to the air inlet device 102, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and completes the cleaning and sterilization of the cleaning pipeline connected to the air inlet device 102 and the material delivery pipeline 31;

[0209] S211, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0210] S212, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the material delivery pipeline 31 corresponding to the air intake device 102, the material delivery multi-way valve 40 and the end of the material distribution device 60, and completes the discharge of the residual cleaning liquid and the pipeline drying;

[0211] S213, closing the material distribution device 60, completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the air intake device 102;

[0212] S311, connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the liquid inlet device 101, and connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the feeding device 103;

[0213] S312, connecting the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the material feed device 103 to the valve ports connected to the cleaning multi-way valve group 70 respectively;

[0214] S313, connecting the material delivery pipelines 31 correspondingly connected to the liquid inlet device 101 and the material feeding device 103 to the two material delivery inlets 41 of the material delivery multi-way valve 40 respectively;

[0215] S314, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port is connected to the inner valve port 111;

[0216] S315, switching the three-way valve of the feeding device 103 so that the cleaning valve port 112 is connected to the feeding valve port 113;

[0217] S316, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipeline 21 corresponding to the liquid inlet device 101 and the material feeding device 103;

[0218] S317, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the feeding device 103;

[0219] S318, start the material distribution device 60, so that the cleaning liquid passes through the three-way valve of the liquid inlet device 101, the cleaning pipeline 21 corresponding to the liquid inlet device 101, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the feeding device 103, the three-way valve of the feeding device 103, the material delivery pipeline 31 corresponding to the feeding device 103, and the material delivery multi-way valve 40 to the end of the material distribution device 60, completing the cleaning and sterilization of the cleaning pipeline connected to the feeding device 103 and the material delivery pipeline 31;

[0220] S411, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0221] S412, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the air intake device 102 and the feed device 103;

[0222] S413, switching the three-way valve of the feeding device 103 so that the cleaning valve port 112 is connected to the feeding valve port 113;

[0223] S414, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the feeding device 103;

[0224] S415, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the cleaning pipeline corresponding to the air intake device 102, the main bypass channel 701 of the cleaning multi-way valve group 70, the branch bypass channel 702 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the feeding device 103, the three-way valve of the feeding device 103, the material delivery pipeline 31 corresponding to the feeding device 103, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and the residual liquid of the cleaning liquid is discharged and the pipeline is dried;

[0225] S415, closing the material distribution device 60, completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the feeding device 103;

[0226] S511, switching the three-way valve of the liquid inlet device 101 so that the inner valve port 111 is connected to the feed valve port 113;

[0227] S512, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the liquid inlet device 101;

[0228] S513, start the material distribution device 60 to complete the cleaning and sterilization of the material delivery pipeline 31 connected to the liquid inlet device 101;

[0229] S611, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0230] S612, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the air inlet device 102 and the liquid inlet device 101;

[0231] S613, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the feed valve port 113;

[0232] S614, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the liquid inlet device 101;

[0233] S615, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the cleaning pipeline corresponding to the air intake device 102, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the liquid intake device 101, the three-way valve of the liquid intake device 101, the material delivery pipeline 31 corresponding to the liquid intake device 101, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and the residual liquid of the cleaning liquid is discharged and the pipeline is dried;

[0234] S616, closing the material distribution device 60, and completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the liquid inlet device 101.

[0235] It is understood that the cleaning liquid may include water, bleach, acid and alkali solution, alcohol, organic solvent, etc. The gas may include air, nitrogen, helium, high-temperature steam, etc. The materials to be packaged may include reagents, beverages, etc.

[0236] It can be further understood that when the in-situ cleaning and dispensing system has multiple liquid inlet devices 101, multiple air inlet devices 102, and multiple feeding devices 103, steps S1, S2 or steps S3 and S4 or steps S5 and S6 can be selectively performed again. It can be understood that the principles of the initialization process are the same, and they all switch or repeat between cleaning and sterilization and emptying and drying according to needs. Therefore, this application will no longer give examples one by one to describe in detail the implementation process of the specific steps of initialization when the in-situ cleaning device has different numbers of liquid inlet devices 101, different numbers of air inlet devices 102, and different numbers of feeding devices 103.

[0237] In one embodiment, the cleaning liquid of the liquid inlet device 101 is ethanol, and the gas of the gas inlet device 102 is clean air.

[0238] See also Fig.11The present invention provides a material dispensing method 300 for an in-situ cleaning material dispensing system, comprising the above-mentioned in-situ cleaning material dispensing system, defining a material supply device whose material supply source 15 is gas as an air intake device 102, defining a material supply device whose material supply source 15 is a cleaning liquid as a liquid intake device 101, and defining a material supply device whose material supply source 15 is a material to be packaged as a feeding device 103; defining a path formed by the material supply source 15, the reversing valve 11, the cleaning pipeline 21 along the liquid intake device 101 to the cleaning multi-way valve as a first cleaning output branch, defining a path formed by the material supply source 15, the reversing valve 11, the material delivery pipeline 31 along the liquid intake device 101 to the material delivery multi-way valve 40 as a second Clean output branch; define the path formed along the reversing valve 11 and the cleaning pipeline 21 of the air intake device 102 to the cleaning multi-way valve as the first gas branch, and define the path formed along the reversing valve 11 and the material delivery pipeline 31 of the air intake device 102 to the material delivery multi-way valve 40 as the second gas branch; define the path formed along the reversing valve 11 and the cleaning pipeline 21 of the feeding device 103 to the cleaning multi-way valve as the first material branch, and define the path formed along the reversing valve 11 and the material delivery pipeline 31 of the feeding device 103 to the material delivery multi-way valve 40 as the second material branch; define the path formed from the material delivery multi-way valve 40 to the end of the material distribution device 60 as the material distribution main path;

[0239] Methods include:

[0240] Q1, select the target material to be packaged, and based on the feeding device 103 where the selected target material to be packaged is located, only connect the second material branch to the material distribution main road; start the material distribution equipment 60, so that the target material to be packaged is output along the second material branch to the end of the material distribution main road, so as to complete the packaging of the target material to be packaged;

[0241] F1, select the target cleaning liquid, and based on the feeding device 103 where the selected target cleaning liquid is located, only connect the second cleaning output branch to the material distribution main road; start the material distribution device 60, so that the target cleaning liquid is output along the second cleaning output branch to the end of the material distribution main road, so as to complete the cleaning of the material distribution main road;

[0242] F2, select the target gas, based on the air intake device 102 where the selected target gas is located, only connect the second gas branch and the material distribution main path; start the material distribution equipment 60, so that the target gas is output along the second gas branch to the end of the material distribution main path, so as to complete the emptying and drying of the material distribution main path.

[0243] See also Fig.12 In one embodiment, after step Q1, the method further includes the following steps:

[0244] Q2, determine whether the selected target material to be packaged is the same as the previous packaged material;

[0245] If they are the same, execute step Q1; if they are different, execute step F1 and step F2, and based on the feeding device 103 where the selected target material to be packaged is located, only connect the second material branch to the material distribution main road; start the material distribution equipment 60, so that the target material to be packaged is output along the second material branch to the end of the material distribution main road, so as to complete the packaging of the selected target material to be packaged.

[0246] It can be understood that step Q2 can be performed multiple times until all the required multiple materials to be packaged are packaged.

[0247] See also Fig.13 In one embodiment, after step Q1 and / or after step Q2, the following steps are further included:

[0248] H1, select the pre-recovered packaged material and determine whether the residual material in the main material distribution path is the same as the pre-recovered packaged material;

[0249] If they are the same, the material distribution device 60 is started in reverse, so that the residual material from the second material branch to the end of the material distribution main path flows back to the feeding device 103;

[0250] If they are different, after executing step F1 and step F2, switch the passage to the second material branch and the material distribution main route that match the feed source 15 of the pre-recovered packaged material, reversely start the material distribution equipment 60, and make the residual material in the second material branch to the material delivery multi-way valve 40 flow back to the feeding device 103.

[0251] See also Figure 6 and Fig.11 In one embodiment, before step Q1, the following steps are also included:

[0252] S0, pre-sterilize the liquid inlet device 101, the air inlet device 102 and the feed device 103;

[0253] S1, by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, a cleaning liquid is provided and the flow path of the cleaning liquid is switched, so that the cleaning liquid of the liquid inlet device 101 performs initial cleaning on the cleaning pipeline 21 and the material delivery pipeline 31 connected to the air inlet device 102;

[0254] S2, by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, gas is provided and the flow path of the gas is switched, the cleaning liquid in the cleaning pipeline 21 and / or the material delivery pipeline 31 connected to the air intake device 102 is emptied by the gas of the air intake device 102, and the cleaning pipeline 21 and / or the material delivery pipeline 31 connected to the air intake device 102 is dried;

[0255] S3, by cooperating with the cleaning multi-way valve group 70, the feeding multi-way valve 40 and each reversing valve 11, a cleaning liquid is provided and the flow path of the cleaning liquid is switched, so that the cleaning liquid of the liquid inlet device 101 performs initial cleaning on the cleaning pipeline 21 and the feeding pipeline 31 connected to the feeding device 103;

[0256] S4, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and the various reversing valves 11, gas is provided and the gas flow path is switched, and the gas from the air intake device 102 is used to empty the cleaning liquid in the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103, and the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103 are dried.

[0257] See also Figure 7 and Fig.11 In some embodiments, the initialization method further comprises the following steps after step S2 or step S4:

[0258] S5, by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, a cleaning liquid is provided and the flow path of the cleaning liquid is switched, so that the cleaning liquid of the liquid inlet device 101 performs initial cleaning on the material delivery pipeline 31 and / or the cleaning pipeline 21 connected to the liquid inlet device 101;

[0259] S6, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and the various reversing valves 11, gas is provided and the gas flow path is switched, and the gas of the air intake device 102 is used to empty the cleaning liquid in the material delivery pipeline 31 and the cleaning pipeline 21 connected to the liquid inlet device 101, and the cleaning pipeline 21 and the material delivery pipeline 31 connected to the liquid inlet device 101 are dried.

[0260] Furthermore, in one embodiment, S1 includes the steps of:

[0261] S11, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, the first cleaning output branch, the first gas branch, the second gas branch and the material distribution main road are connected; the material distribution device 60 is started, so that the cleaning liquid of the liquid inlet device 101 is output along the first cleaning output branch to the end of the material distribution main road, and the initial cleaning of the cleaning pipeline 21 and the material delivery pipeline 31 connected to the gas inlet device 102 is completed, and the material distribution device 60 is closed;

[0262] S2 includes the steps:

[0263] S21, by cooperating with the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, the second gas branch and the material distribution main road are connected; the material distribution device 60 is started to output the gas in the air intake device 102 along the second gas branch to the end of the material distribution main road, so that the cleaning liquid in the material delivery pipeline 31 connected to the air intake device 102 is emptied by the gas of the air intake device 102, and the material delivery pipeline 31 connected to the air intake device 102 is dried, and the material distribution device 60 is closed;

[0264] In one embodiment, S3 includes the steps of:

[0265] S31, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, the first cleaning output branch, the first material branch, the second material branch and the material distribution main road are connected; the material distribution device 60 is started to output the cleaning liquid of the liquid inlet device 101 along the first cleaning output branch to the end of the material distribution main road, and the initial cleaning of the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103 is completed, and the material distribution device 60 is closed;

[0266] S4 includes the steps:

[0267] S41, connect the first gas branch, the first material branch, the second material branch to the material distribution main road through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and the various reversing valves 11; start the material distribution equipment 60, so that the gas of the air intake device 102 is output along the first gas branch to the end of the material distribution main road, so as to use the gas of the air intake device 102 to empty the cleaning liquid in the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103, and dry the cleaning pipeline 21 and the material delivery pipeline 31 connected to the feeding device 103, and close the material distribution equipment 60.

[0268] In one embodiment, S5 comprises the steps of:

[0269] S51, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and each reversing valve 11, the second cleaning output branch is connected to the material distribution main road; the material distribution device 60 is started, so that the cleaning liquid of the liquid inlet device 101 is output along the second cleaning output branch to the end of the material distribution main road, so that the cleaning liquid of the liquid inlet device 101 performs initial cleaning on the material delivery pipeline 31 connected to the liquid inlet device 101;

[0270] S6 comprises the steps of:

[0271] S61, through the cooperation of the cleaning multi-way valve group 70, the material delivery multi-way valve 40 and the various reversing valves 11, the first gas branch, the first cleaning output branch, the second cleaning output branch are connected to the material distribution main line; the material distribution equipment 60 is started, and the gas of the air intake device 102 is used to empty the cleaning liquid in the material delivery pipeline 31 and the cleaning pipeline 21 connected to the liquid inlet device 101, and the cleaning pipeline 21 and the material delivery pipeline 31 connected to the liquid inlet device 101 are dried.

[0272] It should be noted that when the flow path of the above-mentioned path is connected through the cooperation of the cleaning multi-way valve group 70, the material feeding multi-way valve 40 and the various reversing valves 11, it means that all other flow paths except this path are blocked, and the gas or cleaning liquid can only flow in this path.

[0273] It should be further explained that each step can be repeated as needed, in other words, it can be cleaned, emptied, and dried multiple times. Specific cleaning strategies, emptying strategies, and drying strategies can be designed and operated according to the difficulty of cleaning the reagents and the degree of dirtiness of the pipelines. They are not listed here one by one.

[0274] Further, in one embodiment, the feeding device in which the feeding source 15 is configured as a gas further includes a one-way valve 12 and a filter 13, and the reversing valve 11 in which the feeding source 15 is configured as a gas feeding device is a three-way valve arranged in an inverted T shape, wherein the inner valve port 111 faces upward and is sequentially connected to the one-way valve 12, the filter 13 and the feeding source 15; the feeding device in which the feeding source 15 is configured as a cleaning liquid or a material to be packaged further includes a storage container 14, a one-way valve 12 and a filter 13, and the storage container 14 is provided with a first hole and a second hole, wherein the first hole is connected to the inner valve port 111 of the reversing valve 11, and the second hole is sequentially connected to the one-way valve 12 and the filter 13;

[0275] Wherein, step S0 comprises the steps of:

[0276] S00, sterilize the three-way valve, storage container, one-way valve 12, and filter 13 of the liquid inlet device 101 under high pressure and high temperature, and put the supply source 15 configured as a cleaning liquid into the sterilized storage container under a sterile environment to obtain a pre-sterilized liquid inlet device 101; or, sterilize the three-way valve, storage container with cleaning liquid, one-way valve 12, and filter 13 of the liquid inlet device 101 under high pressure and high temperature to obtain a pre-sterilized liquid inlet device 101;

[0277] S01, the three-way valve, the one-way valve 12, and the filter 13 of the air intake device 102 are sterilized under high pressure and high temperature, and connected to a gas supply source configured as clean gas to obtain a pre-sterilized air intake device 102; or, the air intake device 102 also includes a storage container, which is connected to a side of the filter 13 away from the three-way valve and is used to store a supply source 15; the three-way valve of the air intake device 102, the storage container with the material to be packaged, the one-way valve 12, and the filter 13 are sterilized under high pressure and high temperature to obtain a pre-sterilized air intake device 102;

[0278] S02, the three-way valve, storage container, one-way valve 12, and filter 13 of the feeding device 103 are sterilized under high pressure and high temperature, and the materials to be packaged are loaded into the sterilized storage container under a sterile environment to complete the pre-sterilized feeding device 103; or, the three-way valve, storage container with materials to be packaged, one-way valve 12, and filter 13 of the feeding device 103 are sterilized under high pressure and high temperature to complete the pre-sterilized feeding device 103.

[0279] It should be noted that step S00, step S01, and step S02 may be performed together or separately.

[0280] In one embodiment, S0 comprises the steps of:

[0281] S03, putting the liquid inlet device 101, the air inlet device 102 and the material feeding device 103 into a high pressure sterilizer for sterilization;

[0282] S04, loading the cleaning liquid into the storage container 14 in the sterilized liquid inlet device 101 under a sterile operating environment; loading the material to be packaged into the storage container 14 in the sterilized material feeding device 103 under a sterile operating environment.

[0283] It can be understood that the gas of the air intake device 102 can be directly connected to sterile clean gas when in use.

[0284] Further, in one embodiment, the reversing valve 11 is a three-way valve; the cleaning multi-way valve group 70 includes a plurality of T-type three-way valves 71 arranged in series, two valve ports of the plurality of T-type three-way valves 71 are connected in parallel and opposite to each other in sequence to form a main bypass channel 701, and the other valve ports of the plurality of T-type three-way valves 71 correspond to form a plurality of branch bypass channels 702; wherein, a feed source 15 configured as a gas feed device and a feed source 15 configured as a cleaning liquid feed device are respectively connected horizontally from both sides to the two valve ports at both ends of the main bypass channel 701 through the cleaning pipeline 21;

[0285] S11 comprises the steps of:

[0286] S111, connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the liquid inlet device 101, and connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the air inlet device 102;

[0287] S112, connecting the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the air inlet device 102 to the valve ports connected to the cleaning multi-way valve group 70 respectively;

[0288] S113, connecting the material delivery pipelines 31 correspondingly connected to the liquid inlet device 101 and the air inlet device 102 to the two material delivery inlets 41 of the material delivery multi-way valve 40 respectively;

[0289] S114, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the inner valve port 111;

[0290] S115, switching the three-way valve of the air intake device 102 so that the cleaning valve port 112 is connected to the feed valve port 113;

[0291] S116, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the air inlet device 102;

[0292] S117, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the air intake device 102;

[0293] S118, start the material distribution device 60, so that the cleaning liquid passes through the three-way valve of the liquid inlet device 101, the cleaning pipeline 21 corresponding to the liquid inlet device 101, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the air inlet device 102, the three-way valve of the air inlet device 102, the material delivery pipeline 31 corresponding to the air inlet device 102, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and completes the cleaning and sterilization of the cleaning pipeline connected to the air inlet device 102 and the material delivery pipeline 31;

[0294] In one embodiment, S21 includes the steps of:

[0295] S211, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0296] S212, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the material delivery pipeline 31 corresponding to the air intake device 102, the material delivery multi-way valve 40 and the end of the material distribution device 60, and completes the discharge of the residual cleaning liquid and the pipeline drying;

[0297] S213, closing the material distribution device 60, completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the air intake device 102;

[0298] In one embodiment, S31 includes the steps of:

[0299] S311, connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the liquid inlet device 101, and connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the feeding device 103;

[0300] S312, connecting the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the material feed device 103 to the valve ports connected to the cleaning multi-way valve group 70 respectively;

[0301] S313, connecting the material delivery pipelines 31 correspondingly connected to the liquid inlet device 101 and the material feeding device 103 to the two material delivery inlets 41 of the material delivery multi-way valve 40 respectively;

[0302] S314, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the inner valve port 111;

[0303] S315, switching the three-way valve of the feeding device 103 so that the cleaning valve port 112 is connected to the feeding valve port 113;

[0304] S316, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipeline 21 corresponding to the liquid inlet device 101 and the material feeding device 103;

[0305] S317, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the feeding device 103;

[0306] S318, start the material distribution device 60, so that the cleaning liquid passes through the three-way valve of the liquid inlet device 101, the cleaning pipeline 21 corresponding to the liquid inlet device 101, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the feeding device 103, the three-way valve of the feeding device 103, the material delivery pipeline 31 corresponding to the feeding device 103, and the material delivery multi-way valve 40 to the end of the material distribution device 60, completing the cleaning and sterilization of the cleaning pipeline connected to the feeding device 103 and the material delivery pipeline 31;

[0307] In one embodiment, S41 includes the steps of:

[0308] S411, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the cleaning valve port 112;

[0309] S412, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the air intake device 102 and the feed device 103;

[0310] S413, switching the three-way valve of the feeding device 103 so that the cleaning valve port 112 is connected to the feeding valve port 113;

[0311] S414, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the feeding device 103;

[0312] S415, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the cleaning pipeline corresponding to the air intake device 102, the main bypass channel 701 of the cleaning multi-way valve group 70, the branch bypass channel 702 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the feeding device 103, the three-way valve of the feeding device 103, the material delivery pipeline 31 corresponding to the feeding device 103, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and the residual liquid of the cleaning liquid is discharged and the pipeline is dried;

[0313] S415, closing the material distribution device 60, completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the feeding device 103;

[0314] In one embodiment, S51 includes the steps of:

[0315] S511, switching the three-way valve of the liquid inlet device 101 so that the inner valve port 111 is connected to the feed valve port 113;

[0316] S512, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the liquid inlet device 101;

[0317] S513, start the material distribution device 60 to complete the cleaning and sterilization of the material delivery pipeline 31 connected to the liquid inlet device 101;

[0318] In one embodiment, S61 includes the steps of:

[0319] S611, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0320] S612, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the air inlet device 102 and the liquid inlet device 101;

[0321] S613, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the feed valve port 113;

[0322] S614, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the liquid inlet device 101;

[0323] S615, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the cleaning pipeline corresponding to the air intake device 102, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the liquid intake device 101, the three-way valve of the liquid intake device 101, the material delivery pipeline 31 corresponding to the liquid intake device 101, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and the residual liquid of the cleaning liquid is discharged and the pipeline is dried;

[0324] S616, closing the material distribution device 60, and completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the liquid inlet device 101.

[0325] It can be understood that when the cleaning pipeline connected to the air intake device 102 and the material delivery pipeline 31 are cleaned and sterilized, the cleaning pipeline connected to the liquid intake device 101 has been cleaned and sterilized. Therefore, the cleaning pipeline connected to the liquid intake device 101 can be sterilized repeatedly in subsequent steps or no longer.

[0326] It is understood that the cleaning liquid may include water, bleach, acid and alkali solution, alcohol, organic solvent, etc. The gas may include air, nitrogen, helium, high-temperature steam, etc. The materials to be packaged may include reagents, beverages, etc.

[0327] It can be further understood that when the in-situ cleaning and dispensing system has multiple liquid inlet devices 101, multiple air inlet devices 102, and multiple feeding devices 103, steps S1, S2 or steps S3 and S4 or steps S5 and S6 can be selectively performed again. It can be understood that the principles of the initialization process are the same, and they all switch or repeat between cleaning and sterilization and emptying and drying according to needs. Therefore, this application will no longer give examples one by one to describe in detail the implementation process of the specific steps of initialization when the in-situ cleaning device has different numbers of liquid inlet devices 101, different numbers of air inlet devices 102, and different numbers of feeding devices 103.

[0328] In one embodiment, the cleaning liquid of the liquid inlet device 101 is ethanol, and the gas of the gas inlet device 102 is clean air.

[0329] Exemplarily, in a specific embodiment, the material dispensing method of the in-situ cleaning material dispensing system comprises the steps of:

[0330] S0, pre-sterilize the liquid inlet device 101, the air inlet device 102 and the feed device 103;

[0331] S111, connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the liquid inlet device 101, and connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the air inlet device 102;

[0332] S112, connecting the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the air inlet device 102 to the valve ports connected to the cleaning multi-way valve group 70 respectively;

[0333] S113, connecting the material delivery pipelines 31 correspondingly connected to the liquid inlet device 101 and the air inlet device 102 to the two material delivery inlets 41 of the material delivery multi-way valve 40 respectively;

[0334] S114, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port is connected to the inner valve port 111;

[0335] S115, switching the three-way valve of the air intake device 102 so that the cleaning valve port 112 is connected to the feed valve port 113;

[0336] S116, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the air inlet device 102;

[0337] S117, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the air intake device 102;

[0338] S118, start the material distribution device 60, so that the cleaning liquid passes through the three-way valve of the liquid inlet device 101, the cleaning pipeline 21 corresponding to the liquid inlet device 101, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the air inlet device 102, the three-way valve of the air inlet device 102, the material delivery pipeline 31 corresponding to the air inlet device 102, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and completes the cleaning and sterilization of the cleaning pipeline connected to the air inlet device 102 and the material delivery pipeline 31;

[0339] S211, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0340] S212, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the material delivery pipeline 31 corresponding to the air intake device 102, the material delivery multi-way valve 40 and the end of the material distribution device 60, and completes the discharge of the residual cleaning liquid and the pipeline drying;

[0341] S213, closing the material distribution device 60, completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the air intake device 102;

[0342] S311, connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the liquid inlet device 101, and connecting the material delivery pipeline 31 and the cleaning pipeline 21 corresponding to the feeding device 103;

[0343] S312, connecting the cleaning pipelines 21 corresponding to the liquid inlet device 101 and the material feed device 103 to the valve ports connected to the cleaning multi-way valve group 70 respectively;

[0344] S313, connecting the material delivery pipelines 31 correspondingly connected to the liquid inlet device 101 and the material feeding device 103 to the two material delivery inlets 41 of the material delivery multi-way valve 40 respectively;

[0345] S314, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port is connected to the inner valve port 111;

[0346] S315, switching the three-way valve of the feeding device 103 so that the cleaning valve port 112 is connected to the feeding valve port 113;

[0347] S316, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipeline 21 corresponding to the liquid inlet device 101 and the material feeding device 103;

[0348] S317, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the feeding device 103;

[0349] S318, start the material distribution device 60, so that the cleaning liquid passes through the three-way valve of the liquid inlet device 101, the cleaning pipeline 21 corresponding to the liquid inlet device 101, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the feeding device 103, the three-way valve of the feeding device 103, the material delivery pipeline 31 corresponding to the feeding device 103, and the material delivery multi-way valve 40 to the end of the material distribution device 60, completing the cleaning and sterilization of the cleaning pipeline connected to the feeding device 103 and the material delivery pipeline 31;

[0350] S411, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0351] S412, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the air intake device 102 and the feed device 103;

[0352] S413, switching the three-way valve of the feeding device 103 so that the cleaning valve port 112 is connected to the feeding valve port 113;

[0353] S414, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the feeding device 103;

[0354] S415, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the cleaning pipeline corresponding to the air intake device 102, the main bypass channel 701 of the cleaning multi-way valve group 70, the branch bypass channel 702 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the feeding device 103, the three-way valve of the feeding device 103, the material delivery pipeline 31 corresponding to the feeding device 103, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and the residual liquid of the cleaning liquid is discharged and the pipeline is dried;

[0355] S415, closing the material distribution device 60, completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the feeding device 103;

[0356] S511, switching the three-way valve of the liquid inlet device 101 so that the inner valve port 111 is connected to the feed valve port 113;

[0357] S512, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the liquid inlet device 101;

[0358] S513, start the material distribution device 60 to complete the cleaning and sterilization of the material delivery pipeline 31 connected to the liquid inlet device 101;

[0359] S611, switching the three-way valve of the air intake device 102 so that the inner valve port 111 is connected to the feed valve port 113;

[0360] S612, closing the other valve ports of the cleaning multi-way valve group 70, and maintaining the main bypass channel 701 in communication with the cleaning pipelines 21 corresponding to the air inlet device 102 and the liquid inlet device 101;

[0361] S613, switching the three-way valve of the liquid inlet device 101 so that the cleaning valve port 112 is connected to the feed valve port 113;

[0362] S614, switching the material delivery multi-way valve 40 to communicate with the material delivery pipeline 31 corresponding to the liquid inlet device 101;

[0363] S615, start the material distribution device 60, so that the gas passes through the three-way valve of the air intake device 102, the cleaning pipeline corresponding to the air intake device 102, the main bypass channel 701 of the cleaning multi-way valve group 70, the cleaning pipeline 21 corresponding to the liquid intake device 101, the three-way valve of the liquid intake device 101, the material delivery pipeline 31 corresponding to the liquid intake device 101, and the material delivery multi-way valve 40 to the end of the material distribution device 60, and the residual liquid of the cleaning liquid is discharged and the pipeline is dried;

[0364] S616, closing the material distribution device 60, and completing the initialization process of the cleaning pipeline and the material delivery pipeline 31 connected to the liquid inlet device 101.

[0365] Q1, select the target material to be packaged, and based on the feeding device 103 where the selected target material to be packaged is located, only connect the second material branch to the material distribution main road; start the material distribution equipment 60, so that the target material to be packaged is output along the second material branch to the end of the material distribution main road, so as to complete the packaging of the target material to be packaged;

[0366] F1, select the target cleaning liquid, and based on the feeding device 103 where the selected target cleaning liquid is located, only connect the second cleaning output branch to the material distribution main road; start the material distribution device 60, so that the target cleaning liquid is output along the second cleaning output branch to the end of the material distribution main road, so as to complete the cleaning of the material distribution main road;

[0367] F2, select the target gas, based on the air intake device 102 where the selected target gas is located, only connect the second gas branch and the material distribution main path; start the material distribution equipment 60, so that the target gas is output along the second gas branch to the end of the material distribution main path, so as to complete the emptying and drying of the material distribution main path.

[0368] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0369] Those skilled in the art should recognize that the above embodiments are only used to illustrate the present invention, and are not intended to limit the present invention. As long as they are within the spirit of the present invention, appropriate changes and modifications to the above embodiments are within the scope of protection claimed by the present invention.

Claims

1. An in-situ cleaning material distribution system, characterized in that: It includes a feeding device group, a cleaning pipeline group, a cleaning multi-way valve group, a feeding pipeline group, a feeding multi-way valve and a material distribution equipment; The feeding device group includes a plurality of feeding devices, each of which includes a feeding source and a reversing valve, the feeding source of at least one of the feeding devices is gas, the feeding source of at least one of the feeding devices is cleaning liquid, and the feeding source of at least one of the feeding devices is a material to be packaged; the reversing valve has at least three valve ports, which are respectively defined as an inner valve port, a cleaning valve port and a feeding valve port; wherein the inner valve port is connected to the feeding source, the cleaning valve port is connected to one of the valve ports of the cleaning multi-way valve group through a cleaning pipeline in the cleaning pipeline group; the feeding valve port is connected to one of the feeding inlets of the feeding multi-way valve through a feeding pipeline in the feeding pipeline group; the material distributing device is driven and connected to the feeding outlet of the feeding multi-way valve; The cleaning multi-way valve group, the material feeding multi-way valve, and each of the reversing valves can cooperate with each other to switch the provided material supply source and the flow path of the material supply source to complete in-situ cleaning, in-situ feeding, and in-situ material distribution.

2. The in-situ cleaning dispensing system according to claim 1, characterized in that: The reversing valve is a three-way valve.

3. The in-situ cleaning dispensing system according to claim 1, characterized in that: The cleaning multi-way valve group includes a plurality of T-type three-way valves arranged in series, wherein two valve ports of the plurality of T-type three-way valves are connected in parallel and opposite to each other in sequence to form a main bypass channel, and the other valve ports of the plurality of T-type three-way valves correspond to form a plurality of branch bypass channels; wherein a feeding device whose feeding source is configured as a gas and a feeding device whose feeding source is configured as a cleaning liquid are respectively connected horizontally to the two valve ports at both ends of the main bypass channel from both sides through the cleaning pipeline; or, The cleaning multi-way valve group comprises a multi-inlet and single-outlet multi-way switching valve and a single-inlet and multi-outlet multi-way switching valve arranged in series.

4. The in-situ cleaning dispensing system according to claim 1, characterized in that: The feeding device whose feeding source is configured as gas also includes a one-way valve and a filter. The reversing valve of the feeding device whose feeding source is configured as gas is an inverted T-type three-way valve, wherein the inner valve port faces upward and is connected to the one-way valve, the filter and the feeding source in sequence.

5. The in-situ cleaning dispensing system according to claim 4, characterized in that: The supply device in which the supply source is configured as gas further comprises a storage container, wherein the storage container is connected to a side of the filter away from the reversing valve and is used for storing the supply source configured as gas.

6. The in-situ cleaning dispensing system according to claim 1, characterized in that: The feeding device whose feeding source is configured as cleaning liquid or material to be packaged also includes a storage container and a filter. The storage container is provided with a first hole and a second hole, wherein the first hole is connected to the inner valve port of the reversing valve, and the second hole is connected to the filter.

7. The in-situ cleaning dispensing system according to claim 6, characterized in that: The feeding device whose feeding source is configured as a cleaning liquid or a material to be packaged further comprises a one-way valve, and the second hole can be connected to the filter in an on-off manner through the one-way valve.

8. The in-situ cleaning dispensing system according to claim 7, characterized in that: The storage container comprises a receiving portion and a blocking portion connected to each other, and the first hole and the second hole are formed in the blocking portion; Wherein, the blocking portion, the one-way valve, the reversing valve and the filter are an integrated structure.

9. The in-situ cleaning dispensing system according to claim 1, characterized in that: The material delivery multi-way valve is a multi-way switching valve with multiple inlets and a single outlet or multiple inlets and multiple outlets; and / or, The gas includes one or more of air, nitrogen, helium, and high-temperature steam; and / or, The cleaning liquid includes one or more of bleach, acid and alkali solution, organic solvent, alcohol, water, and high-temperature steam.

10. The in-situ cleaning dispensing system according to claim 1, characterized in that: It also includes a liquid separation multi-way head, and the material separation equipment is connected to one of the material delivery outlets of the material delivery multi-way valve through the liquid separation multi-way head.

11. The in-situ cleaning dispensing system according to claim 10, characterized in that: The liquid dispensing multi-way head comprises a main flow channel and a plurality of branch flow channels connected to the same end of the main flow channel; one end of the main flow channel away from the branch flow channel is connected to the material delivery outlet of the material delivery multi-way valve; the other ends of the plurality of branch flow channels are respectively connected to a plurality of liquid dispensing inlets of the material dispensing equipment; Among them, the plurality of branch flow channels are symmetrically arranged along the central axis of the main flow channel in an annular direction, and the central axis of each branch flow channel has an angle with the central axis of the main flow channel, and the angle is a right angle or an acute angle.

12. The in-situ cleaning dispensing system according to claim 11, characterized in that: The degree of the angle is defined as a, 20°≤a≤60°; and / or, The flow channel shapes of the plurality of branch flow channels are the same; and / or, The inner walls of the plurality of branch flow channels have the same smoothness; and / or, The flow channel lengths of the plurality of branch flow channels are equal; and / or, The inner diameters of the plurality of branch flow channels are equal; and / or, The central axes of the plurality of branch flow channels intersect at the same point on the central axis of the main flow channel.

13. The in-situ cleaning dispensing system according to claim 11, characterized in that: Each of the branch flow channels comprises a confluence section and a joint section which are coaxially arranged and connected to each other, one end of the confluence section which is away from the joint section is connected to the main flow channel, and the joint section is used to connect the material distribution equipment; The inner diameter of the joint section is greater than the inner diameter of the confluence section, so as to form a sealing end surface at the junction of the joint section and the confluence section.

14. The in-situ cleaning dispensing system according to claim 13, characterized in that: The dispensing equipment includes a delivery pump, a liquid dispensing pipeline and a liquid dispensing joint. The delivery pump has at least one dispensing liquid inlet and at least one dispensing liquid outlet. The liquid dispensing joint has a first plug-in end and a second plug-in end opposite to each other. The first plug-in end is plugged into the joint section, and the end face of the first plug-in end is face-to-face with the sealing end face. The second plug-in end is connected to one of the dispensing liquid inlets through the liquid dispensing pipeline.

15. The in-situ cleaning dispensing system according to claim 14, characterized in that: It also includes a liquid separation nozzle, which is installed at the liquid dispensing outlet at the end of the material dispensing equipment.

16. The in-situ cleaning dispensing system according to claim 10, characterized in that: Along the gravity direction, the liquid separation multi-way head is installed above the material delivery multi-way valve.

17. The in-situ cleaning dispensing system according to claim 10, characterized in that: The in-situ cleaning and dispensing system also includes an outer shell, in which at least the material feeding multi-way valve and the liquid dispensing multi-way head are installed, and at least part of the outer shell is a transparent shell, which is used to observe the tube body connected to the material feeding multi-way valve and the liquid dispensing multi-way head.

18. The in-situ cleaning dispensing system according to claim 17, characterized in that: The housing comprises a lower supporting shell and an upper protective shell which are connected to each other, and the upper protective shell is a transparent shell.

19. The in-situ cleaning dispensing system according to claim 18, characterized in that: The upper protective shell includes an annular baffle and a cover body, wherein the cover body is disposed on the top of the annular baffle and circumferentially blocks a portion of the side wall of the annular baffle.

20. The in-situ cleaning dispensing system according to claim 19, characterized in that: The in-situ cleaning and dispensing device further comprises at least one pipeline organizing component, which is mounted on the housing, and at least one side of the pipeline organizing component has a plurality of accommodating positions for accommodating the pipe body.

21. The in-situ cleaning dispensing system according to claim 20, characterized in that The pipeline arrangement component is detachably mounted on the housing.

22. The in-situ cleaning dispensing system according to claim 20, characterized in that: At least one side of the pipeline organizer is provided with a mounting slot, and the pipeline organizer is mounted on the top edge of the annular baffle through the mounting slot and is located between the cover body and the annular baffle; or, At least one side of the pipeline organizing piece is provided with a mounting protrusion, and the protective shell is provided with a clamping hole. The pipeline organizing piece is installed on the protective shell through the cooperation between the mounting protrusion and the clamping hole.

23. The in-situ cleaning dispensing system according to claim 10, characterized in that: It also includes a first liquid contacting member, which is circumferentially arranged around the material feeding multi-way valve and the liquid separation multi-way head and is located below the material feeding inlet of the material feeding multi-way valve; and / or, The material dispensing equipment further comprises a second liquid contacting piece, and the second liquid contacting piece is located below the dispensing liquid outlet.

24. The in-situ cleaning dispensing system according to claim 23, characterized in that: It also includes a liquid discharge pipe, through which the first liquid receiving part is connected to the second liquid receiving part.

25. The in-situ cleaning dispensing system according to claim 23, characterized in that: The invention also includes a collecting device, the collecting device includes a storage element, a collecting tube and an anti-return structure, the collecting tube has an input port and an output port, the output port is connected to the storage element, the input port is connected to the first liquid contacting element and / or the second liquid contacting element; the waste liquid enters the collecting tube from the input port and enters the storage element through the output port; Wherein, the anti-return structure is provided between the input port and the output port, and the anti-return structure is used to prevent the waste liquid entering the storage element from flowing back to the output port and / or volatilizing.

26. The in-situ cleaning dispensing system according to claim 25, characterized in that: The anti-return structure is configured as a partial tube body of the collecting tube, and the partial tube body is bent in a U shape to form a liquid-sealed buffer chamber into which a barrier liquid can be injected; alternatively, the anti-return structure is configured as a one-way valve or a float valve.

27. The in-situ cleaning dispensing system according to claim 25, characterized in that: The storage element is provided with an exhaust port, and a gas filter is arranged at the exhaust port.

28. The in-situ cleaning dispensing system according to claim 27, characterized in that: The gas filter element includes an activated carbon filter.

29. The in-situ cleaning dispensing system according to claim 27, characterized in that: The storage element comprises a container bottle and a container cover which are connected to each other, the exhaust port is arranged on the container cover; the gas filter element and the container cover are an integral structure.

30. A liquid dispensing multi-channel head, characterized in that: The liquid-dispensing multi-channel head comprises a main flow channel and a plurality of branch flow channels, one end of each of the plurality of branch flow channels being connected to the same end of the main flow channel; The plurality of branch flow channels are symmetrically arranged along the central axis of the main flow channel in an annular direction, and an angle is formed between the central axis of each branch flow channel and the central axis of the main flow channel, and the angle is a right angle or an acute angle.

31. The liquid dispensing multi-channel head according to claim 30, characterized in that: The degree of the angle is defined as a, 20°≤a≤60°; and / or, The flow channel shapes of the plurality of branch flow channels are the same; and / or, The inner walls of the plurality of branch flow channels have the same smoothness; and / or, The flow channel lengths of the plurality of branch flow channels are equal; and / or, The inner diameters of the plurality of branch flow channels are the same; and / or, The central axes of the plurality of branch flow channels intersect at the same point on the central axis of the main flow channel.

32. The liquid dispensing multi-channel head according to claim 30, characterized in that: Each of the branch flow channels comprises a converging section and a joint section which are coaxially arranged and connected to each other, and one end of the converging section which is away from the joint section is connected to the main flow channel; The inner diameter of the joint section is larger than the inner diameter of the confluence section, so as to form a sealing connection end surface at the junction of the joint section and the confluence section, and the sealing connection end surface can be in surface contact with an external joint surface.

33. A collecting device, characterized in that: It comprises a storage element and a collecting tube, wherein the collecting tube has an input port and an output port, the output port is connected to the storage element, and the object to be collected enters the collecting tube from the input port and enters the storage element through the output port; Wherein, an anti-return structure is further provided between the input port and the output port, and the anti-return structure is used to prevent the objects to be collected that enter the storage element from flowing back to the output port.

34. The collecting device according to claim 33, characterized in that The anti-return structure is configured as a part of the tube body of the collecting tube, and the part of the tube body is bent in a U-shape to form a liquid-sealed buffer chamber into which a barrier liquid can be injected; or, The anti-return structure is configured as a one-way valve or a float valve.

35. The collecting device according to claim 33, characterized in that The storage element is provided with an exhaust port, and a gas filter is arranged at the exhaust port.

36. The collecting device according to claim 35, characterized in that The gas filter element includes an activated carbon filter.

37. The collecting device according to claim 35, characterized in that The storage element comprises a container bottle and a container cover which are connected to each other, the exhaust port is arranged on the container cover; the gas filter element and the container cover are an integral structure.

38. A method for initializing an in-situ cleaning material distribution system, characterized in that: The in-situ cleaning dispensing system according to claim 1 is included, wherein a feeding device whose feeding source is gas is defined as an air intake device, a feeding device whose feeding source is cleaning liquid is defined as a liquid intake device, and a feeding device whose feeding source is a material to be dispensed is defined as a feeding device; the method comprises: S0, pre-sterilizing the liquid inlet device, the air inlet device and the feeding device; S1, providing cleaning liquid and switching the flow path of the cleaning liquid through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the cleaning pipeline and the material delivery pipeline connected to the air inlet device; S2, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, gas is provided and the flow path of the gas is switched, the cleaning liquid in the cleaning pipeline and / or the material delivery pipeline connected to the air intake device is emptied by the gas of the air intake device, and the cleaning pipeline and / or the material delivery pipeline connected to the air intake device is dried; S3, providing cleaning liquid and switching the flow path of the cleaning liquid through the cooperation of the cleaning multi-way valve group, the feeding multi-way valve and each of the reversing valves, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the cleaning pipeline and the feeding pipeline connected to the feeding device; S4, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, gas is provided and the gas flow path is switched, and the gas from the air intake device is used to empty the cleaning liquid in the cleaning pipeline and the material delivery pipeline connected to the feeding device, and the cleaning pipeline and the material delivery pipeline connected to the feeding device are dried.

39. The method for initializing the in-situ cleaning dispensing system according to claim 38, characterized in that: The path formed by the material supply source, reversing valve, cleaning pipeline and cleaning multi-way valve of the liquid inlet device is defined as the first cleaning output branch, and the path formed by the material supply source, reversing valve and material delivery pipeline of the liquid inlet device to the material delivery multi-way valve is defined as the second cleaning output branch; the path formed by the reversing valve and cleaning pipeline of the air inlet device to the cleaning multi-way valve is defined as the first gas branch, and the path formed by the reversing valve and material delivery pipeline of the air inlet device to the material delivery multi-way valve is defined as the second gas branch; the path formed by the reversing valve and cleaning pipeline of the feeding device to the cleaning multi-way valve is defined as the first material branch, and the path formed by the reversing valve and material delivery pipeline of the feeding device to the material delivery multi-way valve is defined as the second material branch; the path formed by the material delivery multi-way valve to the end of the material distribution equipment is defined as the material distribution main path; The S1 comprises the steps of: S11, connecting the first cleaning output branch, the first gas branch, the second gas branch and the material distribution main road through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves; starting the material distribution equipment, so that the cleaning liquid of the liquid inlet device is output along the first cleaning output branch to the end of the material distribution main road, completing the initial cleaning of the cleaning pipeline and the material delivery pipeline connected to the gas inlet device, and closing the material distribution equipment; The S2 comprises the steps of: S21, connecting the second gas branch and the material distribution main road through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves; starting the material distribution equipment, so that the gas in the air intake device is output along the second gas branch to the end of the material distribution main road, so as to use the gas of the air intake device to empty the cleaning liquid in the material delivery pipeline connected to the air intake device, and dry the material delivery pipeline connected to the air intake device, and then close the material distribution equipment.

40. The method for initializing the in-situ cleaning dispensing system according to claim 39, characterized in that: The S3 comprises the steps of: S31, connecting the first cleaning output branch, the first material branch, the second material branch and the material distribution main road through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves; Start the material distribution equipment, so that the cleaning liquid of the liquid inlet device is output along the first cleaning output branch to the end of the material distribution main road, complete the initial cleaning of the cleaning pipeline and the material delivery pipeline connected to the feeding device, and close the material distribution equipment; The S4 comprises the steps of: S41, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, the first gas branch, the first material branch, and the second material branch are connected to the material distribution main road; the material distribution equipment is started to output the gas of the air intake device along the first gas branch to the end of the material distribution main road, so that the gas of the air intake device can be used to empty the cleaning liquid in the cleaning pipeline and the material delivery pipeline connected to the feeding device, and the cleaning pipeline and the material delivery pipeline connected to the feeding device are dried, and the material distribution equipment is closed.

41. The method for initializing the in-situ cleaning dispensing system according to claim 38, characterized in that: The initialization method further comprises the following steps after step S2 or step S4: S5, providing cleaning liquid and switching the flow path of the cleaning liquid through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the material delivery pipeline and / or the cleaning pipeline connected to the liquid inlet device; S6, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, gas is provided and the gas flow path is switched, and the gas of the air intake device is used to empty the cleaning liquid in the material delivery pipeline and the cleaning pipeline connected to the liquid intake device, and the cleaning pipeline and the material delivery pipeline connected to the liquid intake device are dried.

42. The method for initializing the in-situ cleaning dispensing system according to claim 41, characterized in that: The path formed by the material supply source, reversing valve, cleaning pipeline and cleaning multi-way valve of the liquid inlet device is defined as the first cleaning output branch, and the path formed by the material supply source, reversing valve and material delivery pipeline of the liquid inlet device to the material delivery multi-way valve is defined as the second cleaning output branch; the path formed by the reversing valve and cleaning pipeline of the air inlet device to the cleaning multi-way valve is defined as the first gas branch, and the path formed by the reversing valve and material delivery pipeline of the air inlet device to the material delivery multi-way valve is defined as the second gas branch; the path formed by the reversing valve and cleaning pipeline of the feeding device to the cleaning multi-way valve is defined as the first material branch, and the path formed by the reversing valve and material delivery pipeline of the feeding device to the material delivery multi-way valve is defined as the second material branch; the path formed by the material delivery multi-way valve to the end of the material distribution equipment is defined as the material distribution main path; The S5 comprises the steps of: S51, connecting the second cleaning output branch to the material distribution main road through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves; starting the material distribution equipment, so that the cleaning liquid of the liquid inlet device is output along the second cleaning output branch to the end of the material distribution main road, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the material delivery pipeline connected to the liquid inlet device; The S6 comprises the steps of: S61, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, the first gas branch, the first cleaning output branch, and the second cleaning output branch are connected to the material distribution main line; the material distribution equipment is started, and the gas from the air intake device is used to empty the cleaning liquid in the material delivery pipeline and the cleaning pipeline connected to the liquid intake device, and the cleaning pipeline and the material delivery pipeline connected to the liquid intake device are dried.

43. A material dispensing method for an in-situ cleaning material dispensing system, characterized in that: It includes the in-situ cleaning and dispensing system as described in claim 1, defining a feeding device whose feeding source is gas as an air intake device, defining a feeding device whose feeding source is cleaning liquid as a liquid intake device, and defining a feeding device whose feeding source is a material to be packaged as a feeding device; defining a path formed along the feeding source, reversing valve, and cleaning pipeline of the liquid intake device to the cleaning multi-way valve as a first cleaning output branch, and defining a path along the feeding source, reversing valve, and material delivery pipeline of the liquid intake device to the material delivery multi-way valve as a second cleaning output branch; defining a path formed along the reversing valve and cleaning pipeline of the air intake device to the cleaning multi-way valve as a first gas branch, and defining a path formed along the reversing valve and material delivery pipeline of the air intake device to the material delivery multi-way valve as a second gas branch; defining a path formed along the reversing valve and cleaning pipeline of the feeding device to the cleaning multi-way valve as a first material branch, and defining a path formed along the reversing valve and material delivery pipeline of the feeding device to the material delivery multi-way valve as a second material branch; The path from the multi-way valve to the end of the material distribution equipment is defined as the main material distribution path; The method comprises: Q1, select the target material to be packaged, and based on the feeding device where the selected target material to be packaged is located, only connect the second material branch to the material distribution main road; start the material distribution equipment, so that the target material to be packaged is output along the second material branch to the end of the material distribution main road, so as to complete the packaging of the target material to be packaged; F1, select the target cleaning liquid, and based on the feeding device where the selected target cleaning liquid is located, only connect the second cleaning output branch to the material distribution main road; start the material distribution equipment to make the target cleaning liquid output along the second cleaning output branch to the end of the material distribution main road to complete the cleaning of the material distribution main road; F2, select the target gas, and based on the air intake device where the selected target gas is located, only connect the second gas branch and the material distribution main road; start the material distribution equipment to output the target gas along the second gas branch to the end of the material distribution main road to complete the emptying and drying of the material distribution main road.

44. The material dispensing method of the in-situ cleaning material dispensing system according to claim 43, characterized in that: After the Q1 step, the method further includes the following steps: Q2, determine whether the selected target material to be packaged is the same as the previous packaged material; If they are the same, execute step Q1; if they are different, execute step F1 and step F2, and based on the feeding device where the selected target material to be packaged is located, only connect the second material branch to the material distribution main road; start the material distribution equipment to make the target material to be packaged be output along the second material branch to the end of the material distribution main road to complete the packaging of the selected target material to be packaged.

45. The material dispensing method of the in-situ cleaning material dispensing system according to claim 44, characterized in that: After the Q1 step and / or after the Q2 step, the method further includes the following steps: H1, select the pre-recovered packaged material and determine whether the residual material in the main material distribution path is the same as the pre-recovered packaged material; If the material distribution device is the same, the material distribution device is started in reverse, so that the residual material from the second material branch to the end of the material distribution main path flows back to the feeding device; If the material source of the pre-recovered packaged material is different, after executing step F1 and step F2, the passage is switched to a second material branch and a main material distribution passage that match the feed source of the pre-recovered packaged material, and the material distribution equipment is started in reverse, so that the residual material from the second material branch to the material delivery multi-way valve is reversely refluxed to the feeding device.

46. ​​The material dispensing method of the in-situ cleaning material dispensing system according to claim 43, characterized in that: The Q1 step also includes the following steps: S0, pre-sterilizing the liquid inlet device, the air inlet device and the feeding device; S1, providing cleaning liquid and switching the flow path of the cleaning liquid through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the cleaning pipeline and the material delivery pipeline connected to the air inlet device; S2, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, gas is provided and the flow path of the gas is switched, the cleaning liquid in the cleaning pipeline and / or the material delivery pipeline connected to the air intake device is emptied by the gas of the air intake device, and the cleaning pipeline and / or the material delivery pipeline connected to the air intake device is dried; S3, providing cleaning liquid and switching the flow path of the cleaning liquid through the cooperation of the cleaning multi-way valve group, the feeding multi-way valve and each of the reversing valves, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the cleaning pipeline and the feeding pipeline connected to the feeding device; S4, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, gas is provided and the gas flow path is switched, and the gas from the air intake device is used to empty the cleaning liquid in the cleaning pipeline and the material delivery pipeline connected to the feeding device, and the cleaning pipeline and the material delivery pipeline connected to the feeding device are dried.

47. The material dispensing method of the in-situ cleaning material dispensing system according to claim 46, characterized in that: The material distribution method further comprises the following steps after the step S2 or after the step S4: S5, providing cleaning liquid and switching the flow path of the cleaning liquid through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, so that the cleaning liquid of the liquid inlet device performs initial cleaning on the material delivery pipeline and / or the cleaning pipeline connected to the liquid inlet device; S6, through the cooperation of the cleaning multi-way valve group, the material delivery multi-way valve and each of the reversing valves, gas is provided and the gas flow path is switched, and the gas of the air intake device is used to empty the cleaning liquid in the material delivery pipeline and the cleaning pipeline connected to the liquid intake device, and the cleaning pipeline and the material delivery pipeline connected to the liquid intake device are dried.

Citation Information

Patent Citations

  • Fluid drain manifold

    CN104234962A

  • Leaked oil collecting system

    CN220484265U

  • Substrate treatment apparatus, gas supply device, method for cleaning raw material supply pipe, method for manufacturing semiconductor device, and program

    WO2021193406A1

Cited By

  • Liquid-dispensing multi-port manifold, collection device, in-situ cleaning and dispensing system, and method

    WO2026157763A1