Ablation device and readable storage medium

Abstract

The invention provides ablation equipment and a readable storage medium. The ablation equipment comprises a controller, an energy generation module, a blood pressure detection module and a medical catheter, the energy generation module is configured to provide ablation energy to the medical catheter; the blood pressure detection module is configured to collect first blood pressure data in a first preset time window before an operation and collect second blood pressure data in a second preset time window after each ablation; the controller is configured to obtain preoperative dictrotic wave amplitude information according to the first blood pressure data; after each ablation, according to the second blood pressure data after the ablation, acquiring post-ablation dictrotic wave amplitude information corresponding to the ablation, and according to the preoperative dictrotic wave amplitude information and the post-ablation dictrotic wave amplitude information corresponding to the ablation, judging whether the target blood vessel needs to be continuously ablated after the ablation. According to the method, an operator can conveniently judge the immediate ablation effect in the operation, the operation type learning curve is effectively reduced, and the operation response rate and safety are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an ablation device and a readable storage medium. Background Art

[0002] Hypertension is a common chronic disease. If it is not detected and treated early, it will increase the mortality rate of cardiovascular events, stroke and kidney disease. According to the "2020 International Hypertension Practice Guidelines" and World Health Organization documents, hypertension is defined as office systolic blood pressure ≥140mm Hg and / or office diastolic blood pressure ≥90mm Hg after repeated measurements. The higher the blood pressure, the harder it is for the heart to pump blood. If not controlled, high blood pressure can lead to: 1) heart attack, heart enlargement, and eventually heart failure; 2) due to the high pressure, blood vessels may bulge (forming aneurysms), produce weak points, and are more prone to blockage and rupture; 3) blood leaks into the brain, causing stroke; 4) high blood pressure can also cause kidney failure, blindness, and cognitive dysfunction.

[0003] Hypertension is one of the most important risk factors for cardiovascular and cerebrovascular diseases. Although improving lifestyle and drug treatment are effective ways to lower blood pressure, the control rate of hypertension is still very low. Blood pressure is controlled by complex interactions of signals from multiple systems in the body (nervous system, circulatory system, endocrine system, etc.), and the kidneys play a core role in long-term blood pressure regulation. Abnormal renal sympathetic nerves can increase blood pressure through two mechanisms: afferent nerves and efferent nerves. Renal sympathetic denervation (RDN) can significantly reduce renal sympathetic nerve activity and prevent the maintenance and progression of hypertension.

[0004] Renal sympathetic denervation (RDN) achieves the effect of lowering blood pressure by inhibiting the activity of renal sympathetic nerves. Among them, radiofrequency ablation is the most important nerve ablation method. RDN radiofrequency ablation is to percutaneously puncture the radiofrequency ablation catheter through the femoral artery to reach the bilateral renal arteries, control the electrodes on the catheter to release radiofrequency energy in the selected area, so that the renal artery intima produces local high temperature, selectively block the conduction function of the sympathetic nerve fibers on the renal artery wall, reduce the excitability of the sympathetic nerves, and thus achieve the clinical therapeutic effect of lowering blood pressure. Ablation of afferent nerves can reduce the nerve impulses uploaded to the central nervous system and the excitability of the sympathetic nerves, thereby reducing the heart rate, myocardial contractility, and stroke volume, thereby reducing the blood output of the heart and lowering blood pressure; ablation of efferent nerves can reduce the activity of the downstream nerves, thereby increasing the glomerular filtration rate, reducing the renal reabsorption capacity, reducing the reabsorption of sodium ions and water, resulting in more sodium ions and water excreted from the body, reducing blood volume, and lowering blood pressure.

[0005] The existing renal artery ablation devices on the market cannot provide doctors with an immediate and effective feedback mechanism after the operation. This situation results in the lack of a clear and reliable judgment indicator for the operator to confirm whether the operation has achieved the expected results after the operation. Due to the lack of immediate means of evaluating the surgical effect, doctors often find it difficult to accurately judge whether the renal artery ablation operation has completely eliminated the sympathetic nerve control in the target area.

[0006] To make up for this deficiency, some surgeons have proposed to observe whether the blood vessels are dilated through CT images taken immediately after the operation, as an indirect basis for judging whether the sympathetic nerves have lost their innervation. However, although this method may provide doctors with a means of observation to a certain extent, it inevitably increases the burden of radiation exposure on patients. Postoperative patients are in a relatively weak state, and additional radiation exposure will undoubtedly have an adverse effect on their postoperative recovery and may even increase potential health risks.

[0007] In addition, the measurement accuracy of vascular dilation observed through CT images is relatively low. Due to the limitations of factors such as the spatial resolution and contrast of CT images, doctors may encounter certain difficulties in interpreting images and find it difficult to accurately judge the true state of blood vessels. This not only increases the uncertainty of diagnosis, but may also mislead doctors' judgment of the effectiveness of surgery, thereby affecting subsequent treatment decisions and the patient's recovery process.

[0008] It should be noted that the information disclosed in the background technology section of the invention is only intended to deepen the understanding of the general background technology of the invention, and should not be regarded as an admission or suggestion in any form that the information constitutes prior art already known to those skilled in the art. Summary of the invention

[0009] The purpose of the present invention is to provide an ablation device and a readable storage medium, which can not only facilitate the operator to judge the immediate ablation effect (denervation effect) during the operation, effectively reduce the learning curve of the procedure, improve the surgical response rate and safety, but also effectively shorten the surgical radiation exposure time and reduce the patient's pain.

[0010] To achieve the above-mentioned purpose, the present invention provides an ablation device, including a controller, an energy generation module, a blood pressure detection module and a medical catheter, wherein the energy generation module and the blood pressure detection module are both communicatively connected to the controller, and the medical catheter is electrically connected to the energy generation module; the energy generation module is configured to provide ablation energy to the medical catheter under the control of the controller to ablate the target blood vessel; the blood pressure detection module is configured to collect first blood pressure data within a first preset time window before the operation, and collect second blood pressure data within a second preset time window after each ablation, and transmit the first blood pressure data and the second blood pressure data to the controller; the controller is configured to: obtain preoperative dicrotic wave amplitude information according to the first blood pressure data; after each ablation, obtain the post-ablation dicrotic wave amplitude information corresponding to the ablation according to the second blood pressure data after the ablation, and judge whether it is necessary to continue to ablate the target blood vessel after the ablation according to the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation.

[0011] Optionally, the controller is configured to: obtain the preoperative dicrotic wave amplitude information based on the average value of the amplitudes of each dicrotic wave in the first blood pressure data; after each ablation, obtain the post-ablation dicrotic wave amplitude information corresponding to the ablation based on the average value of the amplitudes of each dicrotic wave in the second blood pressure data after the ablation.

[0012] Optionally, the controller is configured to: after each ablation, obtain the dicrotic wave amplitude change information corresponding to the ablation based on the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, and determine whether it is necessary to continue ablation of the target blood vessel after the ablation based on the dicrotic wave amplitude change information corresponding to the ablation.

[0013] Optionally, the dicrotic wave amplitude change information includes any one of dicrotic wave amplitude decrease amount information and dicrotic wave amplitude decrease percentage information.

[0014] Optionally, the controller is configured as follows: if the decrease in the dicrotic wave amplitude corresponding to the ablation is less than a first preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to the ablation is less than a first preset percentage, then it is determined that it is necessary to continue ablation of the target blood vessel after the ablation, and the energy generating module is controlled to increase the output power to continue ablation at the ablation site corresponding to the ablation, or the operator is prompted to move the medical catheter to the next ablation site to continue ablation.

[0015] Optionally, the controller is configured as follows: if the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, then it is determined that it is necessary to continue ablation of the target blood vessel after the ablation, and the surgical operator is prompted to move the medical catheter to the next ablation site to continue ablation or to the vicinity of the ablation site corresponding to the ablation to continue ablation.

[0016] Optionally, the controller is further configured to: if the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the percentage of the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, then control the energy generating module to provide stimulation energy to the medical catheter to stimulate the ablation site corresponding to the ablation; if the average value of the dicrotic wave amplitude during the stimulation process is greater than the average value of the dicrotic wave amplitude before stimulation, then prompt the surgical operator to move the medical catheter to the vicinity of the ablation site corresponding to the ablation to continue ablation.

[0017] Optionally, the controller is configured to determine that it is not necessary to continue ablating the target blood vessel if the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is stable within the preset time after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is stable within the preset time after the ablation.

[0018] Optionally, the controller is configured to prompt the operator to move the medical catheter to the next ablation site to continue ablation if the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than a second preset amplitude and the dicrotic wave fluctuation is unstable within a preset time period after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than a second preset percentage and the dicrotic wave fluctuation is unstable within a preset time period after the ablation.

[0019] Optionally, the energy generation module is also configured to provide stimulation energy to the medical catheter under the control of the controller to stimulate the target blood vessel; the blood pressure detection module is also configured to: collect third blood pressure data within a third preset time window before each stimulation, and collect fourth blood pressure data during each stimulation; the controller is also configured to: for each stimulation: obtain the average value of the pre-stimulation dicrotic wave amplitude corresponding to the stimulation according to the third blood pressure data before the stimulation; obtain the average value of the stimulation dicrotic wave amplitude corresponding to the stimulation according to the fourth blood pressure data during the stimulation; if the average value of the stimulation dicrotic wave amplitude corresponding to the stimulation is greater than the average value of the pre-stimulation dicrotic wave amplitude corresponding to the stimulation, then it is determined that the stimulation site corresponding to the stimulation is an ablation site where sympathetic nerves exist.

[0020] Optionally, the ablation device provided by the present invention further includes a display module communicatively connected to the controller, and the display module is configured to display the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information.

[0021] Optionally, the blood pressure detection module is further configured to collect the fifth blood pressure data within each fourth preset time window during each ablation process and transmit it to the controller; the controller is further configured to: obtain pre-operative systolic blood pressure information, pre-operative diastolic blood pressure information, pre-operative pulse pressure difference information and pre-operative pulse information according to the first blood pressure data; before each ablation, obtain the pre-ablation systolic blood pressure information, pre-ablation diastolic blood pressure information, pre-ablation pulse pressure difference information, pre-ablation pulse information and pre-ablation dicrotic wave amplitude information corresponding to the ablation according to the sixth blood pressure data before the ablation, and obtain the pre-ablation systolic blood pressure information, pre-ablation diastolic blood pressure information, pre-ablation pulse pressure difference information, pre-ablation pulse information and pre-ablation dicrotic wave amplitude information according to the ablation result; The corresponding pre-ablation dicrotic wave amplitude information and post-ablation dicrotic wave amplitude information are used to obtain the single ablation dicrotic wave amplitude decrease information corresponding to the ablation; after each ablation, the post-ablation systolic pressure information, post-ablation diastolic pressure information, post-ablation pulse pressure difference information and post-ablation pulse information corresponding to the ablation are obtained according to the second blood pressure data after the ablation, and the single ablation dicrotic wave amplitude decrease information corresponding to the ablation is obtained according to the pre-ablation dicrotic wave amplitude information and post-ablation dicrotic wave amplitude information corresponding to the ablation; in each ablation process, according to each blood pressure data of the ablation process, The fifth blood pressure data within the fourth preset time window obtains real-time systolic pressure information, real-time diastolic pressure information, real-time pulse pressure difference information, real-time pulse information and real-time dicrotic wave amplitude information, and obtains real-time dicrotic wave amplitude change information according to the preoperative dicrotic wave amplitude information and the real-time dicrotic wave amplitude information; the display module is also configured to provide a surgical interface and / or an ablation review interface; the surgical interface is configured to: during each ablation process, the preoperative systolic pressure information, the preoperative diastolic pressure information, the preoperative pulse pressure difference information, the preoperative pulse information, the preoperative dicrotic wave amplitude The information, the real-time systolic pressure information, the real-time diastolic pressure information, the real-time pulse pressure difference information, the real-time pulse information and the real-time dicrotic wave amplitude information are displayed; the ablation review interface is configured as follows: after each ablation, the pre-ablation systolic pressure information, the pre-ablation diastolic pressure information, the pre-ablation pulse pressure difference information, the pre-ablation pulse information, the pre-ablation dicrotic wave amplitude information, the post-ablation systolic pressure information, the post-ablation diastolic pressure information, the post-ablation pulse pressure difference information, the post-ablation pulse information, the post-ablation dicrotic wave amplitude information and the single ablation dicrotic wave amplitude decrease information corresponding to the ablation are displayed.

[0022] To achieve the above object, the present invention further provides a readable storage medium, wherein the readable storage medium stores a computer program, and when the computer program is executed by a processor, the following steps are implemented:

[0023] Acquiring preoperative dicrotic wave amplitude information according to first blood pressure data collected within a first preset time window before the operation;

[0024] Controlling the energy generation module to provide ablation energy to the medical catheter to ablate the target blood vessel;

[0025] After each ablation, the post-ablation dicrotic wave amplitude information corresponding to the ablation is obtained based on the second blood pressure data collected within a second preset time window after the ablation, and based on the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, it is determined whether it is necessary to continue ablation of the target blood vessel after the ablation.

[0026] Optionally, judging whether it is necessary to continue ablation of the target blood vessel after the ablation according to the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, includes:

[0027] According to the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, the dicrotic wave amplitude change information corresponding to the ablation is obtained, and according to the dicrotic wave amplitude change information corresponding to the ablation, it is determined whether it is necessary to continue ablation of the target blood vessel after the ablation.

[0028] Optionally, the obtaining the dicrotic wave amplitude change information corresponding to the ablation according to the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation includes:

[0029] According to the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, the dicrotic wave amplitude reduction amount information or the dicrotic wave amplitude reduction percentage information corresponding to the ablation is obtained.

[0030] Optionally, judging whether it is necessary to continue ablation of the target blood vessel after the ablation according to the dicrotic wave amplitude change information corresponding to the ablation, includes:

[0031] If the decrease in the dicrotic wave amplitude corresponding to this ablation is less than the first preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to this ablation is less than the first preset percentage, it is determined that it is necessary to continue ablation of the target blood vessel after this ablation, and the energy generating module is controlled to increase the output power to continue ablation at the ablation site corresponding to this ablation, or the operator is prompted to move the medical catheter to the next ablation site to continue ablation.

[0032] Optionally, judging whether it is necessary to continue ablation of the target blood vessel after the ablation according to the dicrotic wave amplitude change information corresponding to the ablation, includes:

[0033] If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, it is determined that it is necessary to continue ablation of the target blood vessel after the ablation, and the operator is prompted to move the medical catheter to the next ablation site to continue ablation or to the vicinity of the ablation site corresponding to the ablation to continue ablation.

[0034] Optionally, if the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the percentage of the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, the energy generating module is controlled to provide stimulation energy to the medical catheter to stimulate the ablation site corresponding to the ablation. If the average value of the dicrotic wave amplitude during the stimulation process is greater than the average value of the dicrotic wave amplitude before stimulation, the operator is prompted to move the medical catheter to the vicinity of the ablation site corresponding to the ablation to continue the ablation.

[0035] Optionally, judging whether it is necessary to continue ablation of the target blood vessel after the ablation according to the dicrotic wave amplitude change information corresponding to the ablation, includes:

[0036] If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is stable within the preset time length after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is stable within the preset time length after the ablation, it is determined that there is no need to continue ablation of the target blood vessel; if the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is unstable within the preset time length after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is unstable within the preset time length after the ablation, the operator is prompted to move the medical catheter to the next ablation site to continue ablation.

[0037] Compared with the prior art, the ablation device and readable storage medium provided by the present invention have the following beneficial effects:

[0038] During an ablation operation, when the sympathetic nerves are effectively ablated, the blood vessel regions innervated by the sympathetic nerves will experience a significant decrease in peripheral resistance, which manifests as a significant change in the dicrotic wave. Therefore, the ablation device provided by the present invention uses an energy generation module to provide ablation energy to the medical catheter to ablate the target blood vessel; uses a blood pressure detection module to collect first blood pressure data within a first preset time window before the operation and collects second blood pressure data within a second preset time window after each ablation; obtains preoperative dicrotic wave amplitude information based on the first blood pressure data; and obtains post-ablation dicrotic wave amplitude information corresponding to each ablation based on the second blood pressure data after the ablation after each ablation. Therefore, for each ablation, timely feedback on the surgical effect after the ablation can be provided based on the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, thereby helping the operator to determine whether the sympathetic nerves have lost their innervation. In summary, it can be seen that the ablation device provided by the present invention can not only facilitate the operator to judge the immediate ablation effect (denervation effect) during the operation, effectively reduce the learning curve of the procedure, improve the surgical response rate and safety, but also effectively shorten the surgical radiation exposure time and reduce the patient's pain. In addition, since the damage to the sympathetic nerves caused by ablation and the effect of the sympathetic nerves on vascular dilation after losing control are a cumulative process, the ablation device provided by the present invention can effectively ensure the accuracy of the judgment result by judging whether it is necessary to continue to ablate the target blood vessel after each ablation based on the post-ablation dicrotic wave amplitude information corresponding to the ablation and the preoperative dicrotic wave amplitude information.

[0039] Since the readable storage medium provided by the present invention and the ablation device provided by the present invention belong to the same inventive concept, the readable storage medium provided by the present invention at least has all the beneficial effects of the ablation device provided by the present invention. For details, please refer to the above description of the beneficial effects of the ablation device provided by the present invention. Therefore, the beneficial effects of the readable storage medium provided by the present invention will not be described one by one here. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] Figure 1 A schematic diagram of the block structure of an ablation device provided in one embodiment of the present invention;

[0041] Figure 2 A preoperative blood pressure waveform diagram provided for a specific example of the present invention;

[0042] Figure 3 A postoperative blood pressure waveform diagram provided for a specific example of the present invention;

[0043] Figure 4 A flowchart of judging the immediate ablation effect of an ablation device provided in one embodiment of the present invention;

[0044] Figure 5 A schematic diagram of a surgical interface display provided by an embodiment of the present invention;

[0045] Figure 6 A schematic diagram of an ablation review interface display provided by an embodiment of the present invention;

[0046] Figure 7 A schematic diagram of a stimulus review interface provided by one embodiment of the present invention;

[0047] Figure 8 An overall workflow diagram of an ablation device provided in one embodiment of the present invention;

[0048] Fig. 9 A schematic diagram of the workflow of a readable storage medium provided for one embodiment of the present invention.

[0049] The reference numerals are described as follows:

[0050] Controller-100; energy generation module-200; blood pressure detection module-300; medical catheter-400; display module-500; surgical interface-510; freeze window-511; real-time window-512; ablation review interface-520; pre-ablation window-521; post-ablation window-522; stimulation review interface-530. DETAILED DESCRIPTION

[0051] The ablation device and readable storage medium proposed in the present invention are further described in detail below in conjunction with the accompanying drawings and specific embodiments. According to the following description, the advantages and features of the present invention will become clearer. It should be noted that the drawings are in a very simplified form and are not in precise proportions, which are only used to conveniently and clearly assist in explaining the purpose of the present invention. In order to make the purpose, features and advantages of the present invention more obvious and easy to understand, please refer to the drawings. It should be noted that the structure, proportion, size, etc. illustrated in the drawings of this specification are only used to match the content disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the implementation conditions of the present invention. Any structural modification, change in proportional relationship or adjustment of size, under the condition that the effect produced by the present invention and the purpose that can be achieved are the same or similar, should still fall within the scope of the technical content disclosed by the present invention.

[0052] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that the process, method, article or equipment including a series of elements includes not only those elements, but also includes other elements not explicitly listed, or also includes elements inherent to such process, method, article or equipment. In the absence of more restrictions, the elements defined by the statement "comprise one..." do not exclude the existence of other identical elements in the process, method, article or equipment including the elements. The singular forms "a", "an" and "the" include plural objects, the term "or" is generally used in a sense including "and / or", the term "several" is generally used in a sense including "at least one", and the term "at least two" is generally used in a sense including "two or more". In addition, the terms "first", "second" and "third" are used for descriptive purposes only and are not to be understood as indicating or suggesting relative importance or implicitly indicating the number of the indicated technical features.

[0053] In addition, in the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0054] The core idea of ​​the present invention is to provide an ablation device and a readable storage medium, which can not only facilitate the operator to judge the immediate ablation effect (denervation effect) during the operation, effectively reduce the learning curve of the procedure, improve the surgical response rate and safety, but also effectively shorten the surgical radiation exposure time and reduce the patient's pain.

[0055] It should be noted that the readable storage medium provided by the present invention can be applied to the ablation device provided by the present invention. In addition, it should be noted that although the present invention is described by taking the renal artery as the target blood vessel as an example, as those skilled in the art can understand, this does not constitute a limitation of the present invention, and the target blood vessel can also be the aorta or other blood vessels.

[0056] To realize the above idea, the present invention provides an ablation device, please refer to Figure 1 , which is a schematic diagram of the block structure of an ablation device provided by one embodiment of the present invention. Figure 1 As shown, the ablation device provided by the present invention includes a controller 100, an energy generation module 200, a blood pressure detection module 300 and a medical catheter 400. The energy generation module 200 and the blood pressure detection module 300 are both connected to the controller 100 for communication, and the medical catheter 400 is electrically connected to the energy generation module 200; the energy generation module 200 is configured to provide ablation energy to the medical catheter 400 under the control of the controller 100 to ablate the target blood vessel; the blood pressure detection module 300 is configured to collect a first blood pressure within a first preset time window before the operation. The controller 100 is configured to: obtain preoperative dicrotic wave amplitude information according to the first blood pressure data; after each ablation, obtain post-ablation dicrotic wave amplitude information corresponding to the ablation according to the second blood pressure data after the ablation, and determine whether it is necessary to continue ablation of the target blood vessel after the ablation according to the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation.

[0057] During the ablation operation, when the sympathetic nerves are effectively ablated, the blood vessel areas innervated by the sympathetic nerves will experience a significant decrease in peripheral resistance, which is manifested as a significant change in the dicrotic wave. Therefore, the ablation device provided by the present invention uses the energy generation module 200 to provide ablation energy to the medical catheter 400 to ablate the target blood vessel; uses the blood pressure detection module 300 to collect first blood pressure data within a first preset time window before the operation and collects second blood pressure data within a second preset time window after each ablation; obtains preoperative dicrotic wave amplitude information based on the first blood pressure data; and obtains post-ablation dicrotic wave amplitude information corresponding to each ablation based on the second blood pressure data after the ablation after each ablation. Therefore, for each ablation, the surgical effect after the ablation can be fed back in time based on the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, thereby helping the operator to determine whether the sympathetic nerves have lost their innervation. In summary, it can be seen that the ablation device provided by the present invention can not only facilitate the operator to judge the immediate ablation effect (denervation effect) during the operation, effectively reduce the learning curve of the procedure, improve the surgical response rate and safety, but also effectively shorten the surgical radiation exposure time and reduce the patient's pain. In addition, since the damage to the sympathetic nerves caused by ablation and the effect on vascular dilation after the sympathetic nerves lose control are a cumulative process, after each ablation, the immediate ablation effect (denervation effect) during the operation can be accurately fed back according to the post-ablation dicrotic wave amplitude information corresponding to the ablation and the pre-operative dicrotic wave amplitude information. In addition, since the damage to the sympathetic nerves caused by ablation and the effect on vascular dilation after the sympathetic nerves lose control are a cumulative process, the ablation device provided by the present invention can judge whether it is necessary to continue to ablate the target blood vessel after the ablation according to the post-ablation dicrotic wave amplitude information corresponding to the ablation and the pre-operative dicrotic wave amplitude information after each ablation, thereby effectively ensuring the accuracy of the judgment result. In addition, the ablation device provided by the present invention is an integrated device that integrates an energy generation module 200 and a blood pressure detection module 300. It can integrate functions that originally require multiple independent products to work together, avoiding incompatibility problems that may arise when multiple products are connected to each other, and also greatly reduces the clutter of cables in the operating room.

[0058] Specifically, the energy generation module 200 is responsible for accurately controlling the output of ablation energy to ensure the accuracy and safety of surgical operations, while the blood pressure detection module 300 is responsible for real-time monitoring of the patient's blood pressure changes and providing key vital signs information to the surgical operator. The energy generation module 200 and the blood pressure detection module 300 are seamlessly integrated on the device and operated and controlled through a unified user interface, greatly reducing the complexity of clinical operations. This not only improves surgical efficiency, but also reduces the workload of medical staff, providing patients with a safer and more efficient surgical treatment experience.

[0059] Furthermore, the ablation energy provided by the energy generation module 200 may be, but is not limited to, radio frequency energy, pulse energy, ultrasonic energy, etc. Further, the controller 100 may control the energy generation module 200 to provide ablation energy to the medical catheter 400 based on the ablation parameter range set by the user, so as to ablate the target blood vessel. Ablation parameters include ablation power, ablation time, temperature control temperature, etc. Among them, the adjustable range of ablation power is 1W to 30W, preferably 6W to 15W; the adjustable range of ablation time is 1s to 180s, preferably 60s to 90s; the range of temperature control temperature is 40℃ to 50℃, preferably 40℃ to 45℃. Furthermore, the ablation parameter range can be selected and input by the operator through an operation unit such as a keyboard on a display interface provided by the display module 500 hereinafter, the preferred default parameter of the ablation power is 8W, and the preferred default parameter of the ablation time is 90s, and the surgical operator can adjust the ablation power and ablation time according to the patient's blood vessel diameter and the position of the ablation electrode on the medical catheter 400. Furthermore, the blood pressure detection range of the blood pressure detection module 300 is 0 mmHg to 300 mmHg, preferably 50 mmHg to 250 mmHg.

[0060] Furthermore, the blood pressure detection module 300 can be an invasive blood pressure detection device, so that the controller 100 can accurately obtain pre-operative dicrotic wave amplitude information based on the first blood pressure data collected by the blood pressure detection module 300 (invasive blood pressure detection device), and accurately obtain post-ablation dicrotic wave amplitude information based on the second blood pressure data collected by the blood pressure detection module 300 (invasive blood pressure detection device).

[0061] It should be noted that the dicrotic wave is the waveform corresponding to the second heart sound produced by the elastic recoil of the aortic root at the end of cardiac contraction, and its changes are closely related to peripheral vascular resistance. Therefore, through in-depth analysis of the dicrotic wave, the dynamic changes of peripheral vascular resistance before and after ablation can be accurately determined.

[0062] It should also be noted that on the pulse wave waveform (blood pressure waveform), the dicrotic wave is usually located after the main wave (i.e., the systolic peak) and is a smaller peak. It appears on the descending branch of the pulse wave, and the waveform shows an upward trend. The dicrotic wave peak is the highest point of the dicrotic wave waveform. The height of the dicrotic wave is usually lower than the main wave but higher than other reflected waves or tidal waves. By comparing the heights and positions of different waveforms, the dicrotic wave can be more easily identified. In addition, it should be noted that the dicrotic wave amplitude refers to the height between the dicrotic wave peak and the baseline parallel line drawn from the bottom of the descending canyon.

[0063] Furthermore, the present invention does not limit the specific values ​​of the first preset time window and the second preset time window. The specific values ​​of the first preset time window and the second preset time window can be set according to actual needs. The value range of the first preset time window and the second preset time window can be set to 1s to 60s. For example, the first preset time window and the second preset time window can both be set to 10s. It should be noted that, as can be understood by those skilled in the art, the values ​​of the first preset time window and the second preset time window can be the same or different.

[0064] In some exemplary embodiments, the controller 100 is configured to obtain the preoperative dicrotic wave amplitude information according to an average value of the amplitudes of each dicrotic wave in the first blood pressure data.

[0065] Therefore, the present invention can effectively ensure the accuracy and stability of the obtained preoperative dicrotic wave amplitude information by obtaining the preoperative dicrotic wave amplitude information based on the average value of all dicrotic waves in the first blood pressure data collected before the operation, so as to lay a good foundation for accurately feeding back the surgical effect of each ablation.

[0066] In some exemplary embodiments, the controller 100 is configured to: after each ablation, obtain the post-ablation dicrotic wave amplitude information corresponding to the ablation based on the average value of the amplitudes of each dicrotic wave in the second blood pressure data after the ablation.

[0067] Therefore, after each ablation, by obtaining the post-ablation dicrotic wave amplitude information corresponding to the ablation based on the average value of all dicrotic waves in the second blood pressure data collected after the ablation, the accuracy of the obtained post-ablation dicrotic wave amplitude information can be effectively guaranteed, so as to lay a good foundation for accurately feeding back the surgical effect of each ablation.

[0068] In some exemplary embodiments, the controller 100 is configured to: after each ablation, obtain the dicrotic wave amplitude change information corresponding to the ablation based on the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, and determine whether it is necessary to continue ablation of the target blood vessel after the ablation based on the dicrotic wave amplitude change information corresponding to the ablation.

[0069] Therefore, after each ablation, the dicrotic wave amplitude change information corresponding to the ablation is obtained based on the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, so that the ablation effect of the ablation can be accurately fed back based on the dicrotic wave amplitude change information corresponding to the ablation, thereby laying a good foundation for accurately judging whether it is necessary to continue ablation of the target blood vessel.

[0070] In some exemplary embodiments, the dicrotic wave amplitude change information includes any one of dicrotic wave amplitude decrease amount information and dicrotic wave amplitude decrease percentage information.

[0071] During the ablation operation, when the sympathetic nerves are effectively ablated, the vascular area they control will show a significant decrease in peripheral resistance, which is manifested as a significant reduction in the amplitude of the dicrotic wave. Therefore, after each ablation, the ablation effect after the ablation can be accurately fed back based on the information on the decrease in the dicrotic wave amplitude or the percentage of the decrease in the dicrotic wave amplitude corresponding to the ablation.

[0072] Please continue to refer to Figure 2 and Figure 3 ,in, Figure 2 A preoperative blood pressure waveform diagram provided for a specific example of the present invention; Figure 3 This is a blood pressure waveform diagram after surgery provided by a specific example of the present invention. Figure 2 and Figure 3 It can be seen that the amplitude of the dicrotic wave after surgery is significantly lower than that before surgery.

[0073] Specifically, for each ablation, the decrease in dicrotic wave amplitude corresponding to the ablation is equal to the difference between the average value of the dicrotic wave amplitude before the operation and the average value of the dicrotic wave amplitude after the ablation corresponding to the ablation; the percentage of decrease in dicrotic wave amplitude corresponding to the ablation is equal to the percentage of the difference between the average value of the dicrotic wave amplitude before the operation and the average value of the dicrotic wave amplitude after the ablation corresponding to the ablation and the average value of the dicrotic wave amplitude before the operation.

[0074] It should be noted that in some other embodiments, after each ablation, the dicrotic wave amplitude change information corresponding to the ablation can be obtained based on the ratio of the average dicrotic wave amplitude after ablation corresponding to the ablation to the average dicrotic wave amplitude before the ablation.

[0075] Please continue to refer to Figure 4 , which is a flowchart of judging the immediate ablation effect of the ablation device provided by one embodiment of the present invention. Figure 4 As shown, in some exemplary embodiments, the controller 100 is configured as follows: if the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is less than a first preset amplitude, or the percentage of decrease in the dicrotic wave amplitude corresponding to the ablation is less than a first preset percentage, it is determined that it is necessary to continue ablation of the target blood vessel after the ablation, and the energy generation module 200 is controlled to increase the output power to continue ablation at the ablation site corresponding to the ablation, or the surgical operator is prompted to move the medical catheter 400 to the next ablation site to continue ablation.

[0076] When the decrease in the dicrotic wave amplitude corresponding to a certain ablation is less than the first preset amplitude (for example, 2 mmHg), or the decrease in the dicrotic wave amplitude corresponding to the ablation is less than the first preset percentage (for example, 10%), it indicates that the damage to the sympathetic nerves after the ablation is still insufficient, or the sympathetic nerves are buried in a deeper position. Therefore, by determining under this condition that it is necessary to continue ablation of the target blood vessel after the ablation, and controlling the energy generating module 200 to increase the output power to continue ablation at the ablation site corresponding to the ablation, or prompting the operator to move the medical catheter 400 to the next ablation site to continue ablation, the ablation effect of the target blood vessel can be fully guaranteed.

[0077] It should be noted that, although the present invention is described using the first preset amplitude being 2 mmHg and the first preset percentage being 10% as an example, as those skilled in the art can understand, the present invention does not limit the specific values ​​of the first preset amplitude and the first preset percentage, and the specific values ​​of the first preset amplitude and the first preset percentage can be set according to actual conditions.

[0078] Please continue to refer to Figure 4 ,like Figure 4 As shown, in some exemplary embodiments, the controller 100 is configured as follows: if the amount of decrease in the dicrotic wave amplitude corresponding to the current ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the percentage of decrease in the dicrotic wave amplitude corresponding to the current ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, then it is determined that the target blood vessel needs to be continued to be ablated after the current ablation, and the surgical operator is prompted to move the medical catheter 400 to the next ablation site to continue ablation or to the vicinity of the ablation site corresponding to the current ablation to continue ablation.

[0079] When the decrease in the dicrotic wave amplitude corresponding to a certain ablation is greater than or equal to the first preset amplitude (for example, 2 mmHg) and less than or equal to the second preset amplitude (for example, 4 mmHg), or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage (for example, 10%) and less than or equal to the second preset percentage (for example, 20%), it indicates that the ablation of the sympathetic nerves after the ablation is effective and the sympathetic nerves have been significantly damaged, but the amount of damage to the sympathetic nerves is still insufficient. Therefore, by determining under this condition that it is necessary to continue ablation of the target blood vessel after the ablation, and prompting the operator to move the medical catheter 400 to the next ablation site to continue ablation or to the vicinity of the ablation site corresponding to the ablation to continue ablation, the ablation effect of the target blood vessel can be fully guaranteed.

[0080] It should be noted that, although the present invention is described by taking the second preset amplitude as 4 mmHg and the second preset percentage as 20% as an example, as those skilled in the art can understand, the present invention does not limit the specific values ​​of the second preset amplitude and the second preset percentage, and the specific values ​​of the second preset amplitude and the second preset percentage can be set according to actual conditions. It should also be noted that, as those skilled in the art can understand, the surgical operator can slightly adjust the position of the medical catheter 400 (i.e., the position of the electrode) to move the medical catheter 400 to the vicinity of the ablation site corresponding to the ablation (e.g., an area no more than 5 mm away from the original ablation site).

[0081] In some exemplary embodiments, the controller 100 is further configured to: if the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the percentage of the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, then control the energy generating module 200 to provide stimulation energy to the medical catheter 400 to stimulate the ablation site corresponding to the ablation; if the average value of the dicrotic wave amplitude during the stimulation process is greater than the average value of the dicrotic wave amplitude before stimulation, then prompt the surgical operator to move the medical catheter 400 to the vicinity of the ablation site corresponding to the ablation to continue ablation.

[0082] When a specific nerve area is stimulated externally, it will trigger a series of physiological reactions, one of which is vasoconstriction. This vascular contraction reaction will directly lead to an increase in peripheral vascular resistance, which in turn affects the dynamic characteristics of blood circulation, especially the dicrotic wave part in the blood pressure waveform. As a key feature in the blood pressure waveform, the changes in the shape and amplitude of the dicrotic wave can reflect the various physiological states of the vascular system. Under normal circumstances, the appearance of the dicrotic wave is due to the deceleration of blood after the closure of the aortic valve and the reverse flow of blood in the aortic root during ventricular diastole. However, when neural stimulation causes vasoconstriction, this reverse flow will be hindered, causing the shape and amplitude of the dicrotic wave to change. Therefore, the present invention can assist the operator in judging whether there are still activated sympathetic nerves in the vicinity of the ablation site corresponding to the ablation by performing a stimulation to assist in judging when the dicrotic wave amplitude decrease amount corresponding to a certain ablation is greater than or equal to the first preset amplitude (e.g., 2 mmHg) and less than or equal to the second preset amplitude (e.g., 4 mmHg), or the dicrotic wave amplitude decrease percentage is greater than or equal to the first preset percentage (e.g., 10%) and less than or equal to the second preset percentage (e.g., 20%). Specifically, if the average dicrotic wave amplitude during the stimulation process is greater than the average dicrotic wave amplitude before the stimulation, it indicates that there are still activated sympathetic nerves in the vicinity of the current stimulation site (i.e., the ablation site corresponding to the ablation), thereby prompting the operator to move the medical catheter 400 to the vicinity of the ablation site corresponding to the ablation to continue ablation, which can effectively ensure the ablation effect. If the average value of the dicrotic wave amplitude during the stimulation process is less than or equal to the average value of the dicrotic wave amplitude before stimulation, it indicates that there are no activated sympathetic nerves in the vicinity of the current stimulation site (i.e., the ablation site corresponding to this ablation). Therefore, by prompting the surgical operator to move the medical catheter 400 to a new ablation site for ablation, the ablation effect can be effectively guaranteed.

[0083] It should be noted that, as can be understood by those skilled in the art, the surgical operator can fine-tune the position of the medical catheter 400 to move the medical catheter 400 to an area near the ablation site corresponding to the ablation.

[0084] Please continue to refer to Figure 4 ,like Figure 4As shown, in some exemplary embodiments, the controller 100 is configured as follows: if the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is stable within the preset time length after the ablation, or the percentage of the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is stable within the preset time length after the ablation (for example, the percentage of the increase in the dicrotic wave amplitude is less than or equal to 10%), then it is determined that there is no need to continue ablation of the target blood vessel; and / or if the amount of the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is unstable within the preset time length after the ablation, or the percentage of the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is unstable within the preset time length after the ablation (for example, the percentage of the increase in the dicrotic wave amplitude is greater than 10%), then the surgical operator is prompted to move the medical catheter to the next ablation site to continue ablation.

[0085] Since the decrease in the dicrotic wave amplitude corresponding to a certain ablation is greater than the second preset amplitude (e.g., 4 mmHg) or the percentage of the decrease in the dicrotic wave amplitude is greater than the second preset percentage (e.g., 20%) and the dicrotic wave fluctuation is stable (no significant rebound) within the preset time after the ablation, it means that the sympathetic nerve damage after the ablation is more obvious and the ablation effect is more stable, so the operation can be terminated, that is, there is no need to continue ablating the target blood vessel. If the decrease in the dicrotic wave amplitude corresponding to a certain ablation is greater than the second preset amplitude (e.g., 4 mmHg) or the percentage of the decrease in the dicrotic wave amplitude is greater than the second preset percentage (e.g., 20%) and the dicrotic wave fluctuation is not stable (significant rebound) within the preset time after the ablation, it is necessary to continue to find a new ablation site for ablation.

[0086] In some exemplary embodiments, the energy generation module 200 is further configured to provide stimulation energy to the medical catheter 400 under the control of the controller 100 to stimulate the target blood vessel.

[0087] The blood pressure detection module 300 is further configured to collect third blood pressure data within a third preset time window before each stimulation, and collect fourth blood pressure data during each stimulation.

[0088] The controller 100 is also configured to: for each stimulation: obtain the average value of the pre-stimulation dicrotic wave amplitude corresponding to the stimulation according to the third blood pressure data before the stimulation; obtain the average value of the stimulation dicrotic wave amplitude corresponding to the stimulation according to the fourth blood pressure data during the stimulation; if the average value of the stimulation dicrotic wave amplitude corresponding to the stimulation is greater than the average value of the pre-stimulation dicrotic wave amplitude corresponding to the stimulation, then determine that the stimulation site corresponding to the stimulation is an ablation site where sympathetic nerves exist.

[0089] Since the sympathetic nerves are part of the autonomic nervous system, their activity state has an important influence on vascular tension, heart rate, and the functions of various internal organs. When nerve stimulation causes vasoconstriction, this reverse flow will be hindered, thereby changing the shape and amplitude of the dicrotic wave. Therefore, the present invention can not only determine the activation state of the sympathetic nerves by monitoring the changes in the dicrotic wave during the stimulation process to confirm whether there are sympathetic nerves at the stimulation site, but also further analyze its mechanism of action under specific physiological or pathological conditions. In addition, the present invention can effectively improve the surgical response rate and avoid reducing the surgical success rate due to inaccurate sympathetic nerve ablation sites by coordinating stimulation to find sympathetic nerve ablation sites.

[0090] It should be noted that, as those skilled in the art can understand, the present invention does not limit the specific value of the third preset time window. The specific value of the third preset time window can be set according to actual conditions. The value range of the third preset time window can be 1s to 60s. For example, the third preset time window can be set to 10s.

[0091] Please continue to refer to Figure 1 ,like Figure 1 As shown, in some exemplary embodiments, the ablation device provided by the present invention further includes a display module 500 in communication connection with the controller 100, and the display module 500 is configured to: display the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information. Thus, by displaying the preoperative dicrotic wave amplitude information, the preoperative dicrotic wave amplitude information can be intuitively displayed to the surgical operator; by displaying the post-ablation dicrotic wave amplitude information corresponding to each ablation, the post-ablation dicrotic wave amplitude information after each ablation can be intuitively displayed to the surgical operator.

[0092] In some exemplary embodiments, the controller 100 is further configured to: obtain preoperative systolic blood pressure information, preoperative diastolic blood pressure information, preoperative pulse pressure difference information, and preoperative pulse information based on the first blood pressure data; and after each ablation, obtain post-ablation systolic blood pressure information, post-ablation diastolic blood pressure information, post-ablation pulse pressure difference information, and post-ablation pulse information corresponding to the ablation based on the second blood pressure data after the ablation.

[0093] Specifically, the preoperative systolic pressure information can be obtained according to the average value of each systolic pressure in the first blood pressure data; the preoperative diastolic pressure information can be obtained according to the average value of each diastolic pressure in the first blood pressure data; the preoperative pulse pressure difference information can be obtained according to the average value of each pulse pressure difference (the difference between systolic pressure and diastolic pressure) calculated according to the first blood pressure data, and the preoperative pulse information can be obtained according to the average value of the pulse calculated by the first blood pressure data; after each ablation, the post-ablation systolic pressure information corresponding to the ablation is obtained according to the average value of each systolic pressure in the second blood pressure data after the ablation, the post-ablation diastolic pressure information corresponding to the ablation is obtained according to the average value of each diastolic pressure in the second blood pressure data after the ablation, the post-ablation pulse pressure difference information corresponding to the ablation is obtained according to the average value of the pulse pressure difference calculated according to the second blood pressure data after the ablation, and the post-ablation pulse information corresponding to the ablation is obtained according to the average value of the pulse calculated according to the second blood pressure data after the ablation.

[0094] In some exemplary embodiments, the blood pressure detection module 300 is further configured to: collect the fifth blood pressure data within each fourth preset time window in each ablation process and transmit it to the controller 100; the controller 100 is further configured to, during each ablation process, obtain real-time systolic pressure information, real-time diastolic pressure information, real-time pulse pressure difference information, real-time pulse information and real-time dicrotic wave amplitude information according to the fifth blood pressure data within each fourth preset time window in the ablation process, and obtain real-time dicrotic wave amplitude change information according to the preoperative dicrotic wave amplitude information and the real-time dicrotic wave amplitude information.

[0095] Specifically, for each fourth preset time window, the corresponding real-time systolic pressure information can be obtained according to the average value of each systolic pressure in the fifth blood pressure data collected within the fourth preset time window, the corresponding real-time diastolic pressure information can be obtained according to the average value of each diastolic pressure in the fifth blood pressure data collected within the fourth preset time window, the corresponding real-time pulse pressure difference information can be obtained according to the average value of the pulse pressure difference calculated from the fifth blood pressure data collected within the fourth preset time window, the corresponding real-time pulse information can be obtained according to the average value of the pulse calculated from the fifth blood pressure data collected within the fourth preset time window, and the corresponding real-time dicrotic wave amplitude information can be obtained according to the average value of each dicrotic wave amplitude in the fifth blood pressure data collected within the fourth preset time window.

[0096] It should be noted that, as can be understood by those skilled in the art, the present invention does not limit the specific value of the fourth preset time window, and the specific value of the fourth preset time window can be set according to actual needs. The value range of the fourth preset time window can be set to 1s to 60s, for example, the fourth preset time window can be set to 10s. It should also be noted that for each ablation, if the ablation time of the ablation is 60s and the fourth preset time window is 10s, the ablation process of the ablation can be divided into 6 fourth preset time windows, that is, the real-time systolic pressure information, real-time diastolic pressure information, real-time pulse pressure difference information, real-time pulse information and real-time dicrotic wave amplitude information in the ablation process can be updated once every fourth preset time window.

[0097] In some exemplary embodiments, the display module 500 is configured to provide a surgical interface 510 to display the preoperative systolic pressure information, the preoperative diastolic pressure information, the preoperative pulse pressure difference information, the preoperative pulse information, the preoperative dicrotic wave amplitude information, the real-time systolic pressure information, the real-time diastolic pressure information, the real-time pulse pressure difference information, the real-time pulse information, and the real-time dicrotic wave amplitude information during each ablation process, thereby facilitating the surgical operator to more intuitively judge the real-time ablation effect.

[0098] Please continue to refer to Figure 5 , which is a schematic diagram of a surgical interface 510 provided by an embodiment of the present invention. Figure 5 As shown, the surgical interface 510 includes a freeze window 511 and a real-time window 512, wherein the freeze window 511 is configured to display the preoperative systolic pressure information, the preoperative diastolic pressure information, the preoperative pulse pressure difference information, the preoperative pulse information, and the preoperative dicrotic wave amplitude information. The real-time window 512 is configured to display the real-time systolic pressure information, the real-time diastolic pressure information, the real-time pulse pressure difference information, the real-time pulse information, and the real-time dicrotic wave amplitude information. Therefore, this display method can make it easier for the surgical operator to distinguish between preoperative information and intraoperative information.

[0099] In some exemplary embodiments, the blood pressure detection module 300 is further configured to collect sixth blood pressure data within a fifth preset time window before each ablation and transmit it to the controller 100. The controller 100 is further configured to: before each ablation, obtain the pre-ablation systolic pressure information, pre-ablation diastolic pressure information, pre-ablation pulse pressure difference information, pre-ablation pulse information and pre-ablation dicrotic wave amplitude information corresponding to the ablation based on the sixth blood pressure data before the ablation; after each ablation, obtain the single ablation dicrotic wave amplitude decrease information corresponding to the ablation based on the pre-ablation dicrotic wave amplitude information and post-ablation dicrotic wave amplitude information corresponding to the ablation.

[0100] Specifically, before each ablation, the pre-ablation systolic pressure information corresponding to the ablation can be obtained according to the average value of each systolic pressure in the sixth blood pressure data before the ablation, the pre-ablation diastolic pressure information corresponding to the ablation can be obtained according to the average value of each diastolic pressure in the sixth blood pressure data before the ablation, the pre-ablation pulse pressure difference information corresponding to the ablation can be obtained according to the average value of the pulse pressure difference calculated according to the sixth blood pressure data before the ablation, and the pre-ablation pulse information corresponding to the ablation can be obtained according to the average value of the pulse calculated according to the sixth blood pressure data before the ablation. After each ablation, the single ablation dicrotic wave amplitude decrease information corresponding to the ablation can be obtained according to the difference between the pre-ablation dicrotic wave amplitude corresponding to the ablation and the post-ablation dicrotic wave amplitude and the percentage of the pre-ablation dicrotic wave amplitude.

[0101] In some exemplary embodiments, the display module 500 is further configured to provide an ablation review interface 520, so as to display the pre-ablation systolic pressure information, pre-ablation diastolic pressure information, pre-ablation pulse pressure difference information, pre-ablation pulse information, pre-ablation dicrotic wave amplitude information, post-ablation systolic pressure information, post-ablation diastolic pressure information, post-ablation pulse information, post-ablation dicrotic wave amplitude information, and single ablation dicrotic wave amplitude reduction information corresponding to each ablation after each ablation. Thus, it is more convenient for the operator to intuitively compare the ablation effect of the current ablation with that of the previous ablation.

[0102] Please continue to refer to Figure 6 , which is a schematic diagram of the ablation review interface 520 provided in one embodiment of the present invention. Figure 6As shown, the ablation review interface 520 includes a pre-ablation window 521 and a post-ablation window 522. The pre-ablation window 521 is configured to display the pre-ablation systolic pressure information, pre-ablation diastolic pressure information, pre-ablation pulse pressure difference information, pre-ablation pulse information, and pre-ablation dicrotic wave amplitude information corresponding to each ablation. The post-ablation window 522 is configured to display the post-ablation systolic pressure information, post-ablation diastolic pressure information, post-ablation pulse pressure difference information, post-ablation pulse information, post-ablation dicrotic wave amplitude information, and single ablation dicrotic wave amplitude reduction information corresponding to each ablation.

[0103] In some exemplary embodiments, the display module 500 is further configured to provide a stimulation review interface 530 to display the third blood pressure data, the fourth blood pressure data, the percentage of increase in dicrotic wave amplitude, the maximum systolic pressure, the maximum diastolic pressure, and the stimulation parameters corresponding to each stimulation. Thus, the surgical operator can intuitively observe the degree of influence of the stimulation on the vascular system, so that the surgical operator can more deeply understand the role of the sympathetic nerves therein.

[0104] Specifically, for each stimulation, the percentage increase of the dicrotic wave amplitude corresponding to the stimulation can be calculated based on the difference between the average value of the stimulation dicrotic wave amplitude corresponding to the stimulation and the average value of the pre-stimulation dicrotic wave amplitude corresponding to the stimulation and the percentage of the average value of the pre-stimulation dicrotic wave amplitude corresponding to the stimulation.

[0105] Please continue to refer to Figure 7 , which is a schematic diagram of a stimulus review interface 530 provided in one embodiment of the present invention. Figure 7 As shown in the figure, Dicrotic% represents the percentage of increase in the amplitude of the dicrotic wave; IBP represents invasive blood pressure, PR represents pulse, Current represents stimulation current, Pulse represents pulse width, and Freq. represents stimulation frequency.

[0106] The following describes the overall workflow of the ablation device provided by the present invention by taking the renal artery as the target blood vessel. Figure 8 , which is an overall workflow diagram of the ablation device provided by one embodiment of the present invention. Figure 8As shown, after the doctor connects the blood pressure detection module 300 (such as an invasive blood pressure sensor) to the patient and starts it, the device starts to collect blood pressure data in real time and calculates data such as systolic pressure, diastolic pressure, pulse pressure difference, pulse and dicrotic wave amplitude. After a time window (the time window is used to calculate the average value, which can be set to 1-60s, here 10s), the doctor will obtain the preoperative systolic pressure average value, preoperative diastolic pressure average value, preoperative pulse pressure difference average value, preoperative pulse average value and preoperative dicrotic wave amplitude average value on the interface, and can observe the current real-time systolic pressure, diastolic pressure, pulse pressure difference, pulse and dicrotic wave amplitude data in the real-time window 512. When the catheter reaches the first position, the default parameters are selected as the stimulation frequency of 10Hz, the stimulation current of 20mA, the stimulation pulse width of 2ms, and the stimulation time of 60s, and the stimulation is started. During the stimulation process, the changes in the blood pressure curve are observed in real time. The device will also automatically pop up the stimulation review interface 530 after the stimulation. If the dicrotic wave amplitude rises, it is confirmed as an effective treatment position (ablation site). After the stimulation is completed, the default parameters are selected as ablation power of 8W, ablation time of 60s, and temperature control temperature of 40°C. After the ablation is started, the program will first perform ablation with the set parameters and record the blood pressure change curve throughout the process in real time. After the ablation is completed, the ablation review interface 520 will automatically pop up, including the pre-ablation systolic pressure average, pre-ablation diastolic pressure average, pre-ablation pulse pressure difference average, pre-ablation pulse average, and pre-ablation dicrotic wave amplitude average data in the time window before ablation, as well as the post-ablation systolic pressure average, post-ablation diastolic pressure average, post-ablation pulse pressure difference average, post-ablation pulse average, and post-ablation dicrotic wave amplitude average data in the time window after this ablation. The operator can view the blood pressure change amplitude and dicrotic wave change amplitude. If it is less than a certain threshold (for example, 10%), the sympathetic nerves may not be damaged enough, the nerves may be buried in a deeper position, or if it is greater than or equal to a certain threshold (for example, 10% but less than or equal to 20%), it means that the ablation is effective, the sympathetic nerves are damaged, but the total amount of damage is still insufficient, and a stimulation auxiliary judgment can be performed first. If the blood pressure continues to rise during the stimulation process, the electrode position is slightly adjusted near the previous position to continue ablation. If the blood pressure drops or remains unchanged during the stimulation process, it can be adjusted to a new position to repeat the previous steps and restart the stimulation positioning. If it is greater than or equal to a certain threshold (for example, 20%), it means that the sympathetic nerves are obviously damaged, and you can choose to continue to select points for ablation to expand the effect or end the operation. Specifically, after the change in the amplitude of the dicrotic wave reaches 20%, you need to wait for a few minutes to observe whether the effect is stable. If the dicrotic wave fluctuation is stable and there is no significant rebound (for example, the percentage increase in the amplitude of the dicrotic wave is less than or equal to 10%), the operation can be ended, otherwise it is necessary to continue to stimulate to find the sympathetic nerves and perform ablation treatment.

[0107] Furthermore, the ablation device can be combined with a three-dimensional mapping system. Specifically, a positioning sensing element, such as a magnetic positioning sensor or an electrical positioning sensor, is provided at the distal end of the medical catheter 400. By using it in conjunction with the three-dimensional mapping system, a three-dimensional image of the medical catheter 400 and the renal artery can be obtained. The operator can determine the specific position of the medical catheter 400 based on the three-dimensional image, such as at the distal end or middle section of the renal artery.

[0108] Based on the same inventive concept, the present invention also provides a readable storage medium, wherein the readable storage medium stores a computer program. Fig. 9 , which is a schematic diagram of the workflow of a readable storage medium provided by one embodiment of the present invention. Fig. 9 As shown, when the computer program is executed by a processor, the following steps are implemented:

[0109] Step S100: Acquire preoperative dicrotic wave amplitude information based on first blood pressure data collected within a first preset time window before the operation.

[0110] Step S200: Control the energy generation module to provide ablation energy to the medical catheter to ablate the target blood vessel.

[0111] Step S300: After each ablation, based on the second blood pressure data collected within a second preset time window after the ablation, obtain the post-ablation dicrotic wave amplitude information corresponding to the ablation, and based on the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, determine whether it is necessary to continue ablation of the target blood vessel after the ablation.

[0112] During the ablation operation, when the sympathetic nerves are effectively ablated, the blood vessel areas innervated by the sympathetic nerves will experience a significant decrease in peripheral resistance, which is manifested as a significant change in the dicrotic wave. Therefore, the readable storage medium provided by the present invention controls the energy generation module to provide ablation energy to the medical catheter to ablate the target blood vessel; by collecting first blood pressure data within a first preset time window before the operation and collecting second blood pressure data within a second preset time window after each ablation; by obtaining preoperative dicrotic wave amplitude information based on the first blood pressure data; by obtaining post-ablation dicrotic wave amplitude information corresponding to each ablation based on the second blood pressure data after the ablation, and then for each ablation, the surgical effect after the ablation can be fed back in time based on the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, thereby helping the operator to determine whether the sympathetic nerves have lost their innervation. In summary, the readable storage medium provided by the present invention can not only facilitate the operator to judge the immediate ablation effect (denervation effect) during the operation, effectively reduce the learning curve of the procedure, improve the surgical response rate and safety, but also effectively shorten the surgical radiation exposure time and reduce the patient's pain. In addition, since the damage to the sympathetic nerves caused by ablation and the effect of the sympathetic nerves on vascular dilation after losing control are cumulative processes, the present invention determines whether it is necessary to continue to ablate the target blood vessel after each ablation based on the post-ablation dicrotic wave amplitude information corresponding to the ablation and the preoperative dicrotic wave amplitude information, thereby effectively ensuring the accuracy of the judgment result.

[0113] In some exemplary embodiments, obtaining preoperative dicrotic wave amplitude information based on first blood pressure data collected within a first preset time window before the operation includes:

[0114] The preoperative dicrotic wave amplitude information is obtained according to an average value of the amplitudes of the respective dicrotic waves in the first blood pressure data collected within a first preset time window before the operation.

[0115] In some exemplary embodiments, the step of obtaining the post-ablation dicrotic wave amplitude information corresponding to the ablation according to the second blood pressure data collected within a second preset time window after the ablation includes:

[0116] The post-ablation dicrotic wave amplitude information corresponding to the ablation is obtained according to the average value of the amplitudes of the respective dicrotic waves in the second blood pressure data collected within a second preset time window after the ablation.

[0117] In some exemplary embodiments, judging whether it is necessary to continue ablation of the target blood vessel after the ablation according to the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation includes:

[0118] According to the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, the dicrotic wave amplitude change information corresponding to the ablation is obtained, and according to the dicrotic wave amplitude change information corresponding to the ablation, it is determined whether it is necessary to continue ablation of the target blood vessel after the ablation.

[0119] In some exemplary embodiments, the step of obtaining the dicrotic wave amplitude change information corresponding to the ablation according to the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation includes:

[0120] According to the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, the dicrotic wave amplitude reduction amount information or the dicrotic wave amplitude reduction percentage information corresponding to the ablation is obtained.

[0121] In some exemplary embodiments, judging whether it is necessary to continue ablation of the target blood vessel after the ablation according to the dicrotic wave amplitude change information corresponding to the ablation includes:

[0122] If the decrease in the dicrotic wave amplitude corresponding to this ablation is less than the first preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to this ablation is less than the first preset percentage, it is determined that it is necessary to continue ablation of the target blood vessel after this ablation, and the energy generating module is controlled to increase the output power to continue ablation at the ablation site corresponding to this ablation, or the operator is prompted to move the medical catheter to the next ablation site to continue ablation.

[0123] In some exemplary embodiments, judging whether it is necessary to continue ablation of the target blood vessel after the ablation according to the dicrotic wave amplitude change information corresponding to the ablation includes:

[0124] If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, it is determined that it is necessary to continue ablation of the target blood vessel after the ablation, and the operator is prompted to move the medical catheter to the next ablation site to continue ablation or to the vicinity of the ablation site corresponding to the ablation to continue ablation.

[0125] In some exemplary embodiments, if the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the percentage of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, the energy generating module is controlled to provide stimulation energy to the medical catheter to stimulate the ablation site corresponding to the ablation, and if the average value of the dicrotic wave amplitude during the stimulation process is greater than the average value of the dicrotic wave amplitude before stimulation, the operator is prompted to move the medical catheter to the vicinity of the ablation site corresponding to the ablation to continue the ablation.

[0126] In some exemplary embodiments, judging whether it is necessary to continue ablation of the target blood vessel after the ablation according to the dicrotic wave amplitude change information corresponding to the ablation includes:

[0127] If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is stable within the preset time length after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is stable within the preset time length after the ablation, it is determined that there is no need to continue ablation of the target blood vessel; if the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is unstable within the preset time length after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is unstable within the preset time length after the ablation, the operator is prompted to move the medical catheter to the next ablation site to continue ablation.

[0128] In some exemplary embodiments, when the computer program is executed by a processor, the following steps are further implemented:

[0129] The energy generation module is controlled to provide stimulation energy to the medical catheter to stimulate the target blood vessel, and an ablation site is determined according to the stimulation result.

[0130] In some exemplary embodiments, determining the ablation site according to the stimulation result includes:

[0131] For each stimulus:

[0132] Obtaining the average value of the pre-stimulation dicrotic wave amplitude corresponding to the stimulation according to the third blood pressure data collected within the third preset time window before the stimulation;

[0133] Obtaining the average value of the stimulation dicrotic wave amplitude corresponding to the stimulation according to the fourth blood pressure data collected during the stimulation process;

[0134] If the average amplitude of the stimulated dicrotic wave corresponding to the stimulation is greater than the average amplitude of the pre-stimulation dicrotic wave corresponding to the stimulation, it is determined that the stimulation site corresponding to the stimulation is an ablation site where sympathetic nerves exist.

[0135] It should be noted that the readable storage medium provided by the present invention can adopt any combination of one or more computer-readable media. The readable medium can be a computer-readable signal medium or a computer-readable storage medium. The computer-readable storage medium can be, for example, but not limited to, a system, device or component of electricity, magnetism, light, electromagnetic, infrared or semiconductor, or any combination of the above. More specific examples (non-exhaustive enumeration) of computer-readable storage media include: an electrical connection with one or more wires, a portable computer hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber, a portable compact disk read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the above. In this article, a computer-readable storage medium can be any tangible medium containing or storing a program, which can be used by an instruction execution system, a device or a device or used in combination with it.

[0136] It should also be noted that a computer-readable signal medium may include a data signal propagated in a baseband or as part of a carrier wave, which carries a computer-readable program code. Such propagated data signals may take a variety of forms, including but not limited to electromagnetic signals, optical signals, or any suitable combination of the above. A computer-readable signal medium may also be any computer-readable medium other than a computer-readable storage medium, which may send, propagate, or transmit a program for use by or in conjunction with an instruction execution system, apparatus, or device. The program code contained on the computer-readable medium may be transmitted using any suitable medium, including but not limited to wireless, wire, optical cable, etc., or any suitable combination of the above.

[0137] In summary, compared with the prior art, the ablation device and readable storage medium provided by the present invention have the following beneficial effects:

[0138] During the ablation operation, when the sympathetic nerves are effectively ablated, the blood vessel areas innervated by the sympathetic nerves will experience a significant decrease in peripheral resistance, which is manifested as a significant change in the dicrotic wave. Therefore, the present invention uses an energy generation module to provide ablation energy to the medical catheter to ablate the target blood vessel; uses a blood pressure detection module to collect first blood pressure data within a first preset time window before the operation and collects second blood pressure data within a second preset time window after each ablation; obtains preoperative dicrotic wave amplitude information based on the first blood pressure data; and obtains post-ablation dicrotic wave amplitude information corresponding to each ablation based on the second blood pressure data after the ablation. For each ablation, timely feedback on the surgical effect after the ablation can be provided based on the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, thereby helping the operator to determine whether the sympathetic nerves have lost their innervation. In summary, the present invention can not only facilitate the operator to judge the immediate ablation effect (denervation effect) during the operation, effectively reduce the learning curve of the procedure, improve the surgical response rate and safety, but also effectively shorten the surgical radiation exposure time and reduce the patient's pain. In addition, since the damage to the sympathetic nerves caused by ablation and the effect of the sympathetic nerves on vascular dilation after losing control are cumulative processes, the present invention determines whether it is necessary to continue to ablate the target blood vessel after each ablation based on the post-ablation dicrotic wave amplitude information corresponding to the ablation and the preoperative dicrotic wave amplitude information, thereby effectively ensuring the accuracy of the judgment result.

[0139] It should be noted that the computer program code for performing the operation of the present invention can be written in one or more programming languages ​​or a combination thereof, including object-oriented programming languages-such as Java, Smalltalk, C++, and also conventional procedural programming languages-such as "C" language or similar programming languages. The program code can be executed entirely on the user's computer, partially on the user's computer, as an independent software package, partially on the user's computer and partially on a remote computer, or entirely on a remote computer or server. In the case of a remote computer, the remote computer can be connected to the user's computer through any type of network-including a local area network (LAN) or a wide area network (WAN), or can be connected to an external computer (for example, using an Internet service provider to connect through the Internet).

[0140] It should be noted that the above description is only a description of the preferred embodiment of the present invention, and is not any limitation on the scope of the present invention. Any changes and modifications made by a person skilled in the art in the field of the present invention based on the above disclosure are within the scope of protection of the present invention. Obviously, a person skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations fall within the scope of the present invention and its equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. An ablation device, characterized in that: It includes a controller, an energy generation module, a blood pressure detection module and a medical catheter, wherein the energy generation module and the blood pressure detection module are both communicatively connected to the controller, and the medical catheter is electrically connected to the energy generation module; The energy generation module is configured to provide ablation energy to the medical catheter under the control of the controller to ablate the target blood vessel; The blood pressure detection module is configured to collect first blood pressure data within a first preset time window before the operation, collect second blood pressure data within a second preset time window after each ablation, and transmit the first blood pressure data and the second blood pressure data to the controller; The controller is configured as follows: Acquiring preoperative dicrotic wave amplitude information according to the first blood pressure data; After each ablation, the post-ablation dicrotic wave amplitude information corresponding to the ablation is obtained based on the second blood pressure data after the ablation, and based on the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, it is determined whether it is necessary to continue ablation of the target blood vessel after the ablation.

2. The ablation device according to claim 1, characterized in that: The controller is configured as follows: Acquire the preoperative dicrotic wave amplitude information according to the average value of the amplitudes of each dicrotic wave in the first blood pressure data; After each ablation, the post-ablation dicrotic wave amplitude information corresponding to the ablation is obtained according to the average value of the amplitudes of the respective dicrotic waves in the second blood pressure data after the ablation.

3. The ablation device according to claim 1, characterized in that: The controller is configured as follows: After each ablation, the dicrotic wave amplitude change information corresponding to the ablation is obtained based on the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, and it is determined whether it is necessary to continue ablation of the target blood vessel after the ablation based on the dicrotic wave amplitude change information corresponding to the ablation.

4. The ablation device according to claim 3, characterized in that: The dicrotic wave amplitude change information includes any one of dicrotic wave amplitude decrease amount information and dicrotic wave amplitude decrease percentage information.

5. The ablation device according to claim 4, characterized in that: The controller is configured as follows: If the decrease in the dicrotic wave amplitude corresponding to this ablation is less than the first preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to this ablation is less than the first preset percentage, it is determined that it is necessary to continue ablation of the target blood vessel after this ablation, and the energy generating module is controlled to increase the output power to continue ablation at the ablation site corresponding to this ablation, or the operator is prompted to move the medical catheter to the next ablation site to continue ablation.

6. The ablation device according to claim 4, characterized in that: The controller is configured as follows: If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, it is determined that it is necessary to continue ablation of the target blood vessel after the ablation, and the operator is prompted to move the medical catheter to the next ablation site to continue ablation or to the vicinity of the ablation site corresponding to the ablation to continue ablation.

7. The ablation device according to claim 6, characterized in that: The controller is also configured to: If the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the percentage of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, the energy generating module is controlled to provide stimulation energy to the medical catheter to stimulate the ablation site corresponding to the ablation. If the average value of the dicrotic wave amplitude during the stimulation process is greater than the average value of the dicrotic wave amplitude before stimulation, the operator is prompted to move the medical catheter to the vicinity of the ablation site corresponding to the ablation to continue the ablation.

8. The ablation device according to claim 4, characterized in that: The controller is configured as follows: If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is stable within the preset time after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is stable within the preset time after the ablation, it is determined that there is no need to continue ablation of the target blood vessel; and / or If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is unstable within the preset time after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is unstable within the preset time after the ablation, the operator is prompted to move the medical catheter to the next ablation site to continue ablation.

9. The ablation device according to claim 1, characterized in that: The energy generation module is further configured to provide stimulation energy to the medical catheter under the control of the controller to stimulate the target blood vessel; The blood pressure detection module is further configured to: collect third blood pressure data within a third preset time window before each stimulation, and collect fourth blood pressure data during each stimulation; The controller is also configured to: For each stimulus: Obtaining the average value of the pre-stimulation dicrotic wave amplitude corresponding to the stimulation according to the third blood pressure data before the stimulation; Obtaining the average value of the stimulation dicrotic wave amplitude corresponding to the stimulation according to the fourth blood pressure data during the stimulation process; If the average amplitude of the stimulated dicrotic wave corresponding to the stimulation is greater than the average amplitude of the pre-stimulation dicrotic wave corresponding to the stimulation, it is determined that the stimulation site corresponding to the stimulation is an ablation site where sympathetic nerves exist.

10. The ablation device according to claim 1, characterized in that: It also includes a display module that is communicatively connected to the controller, and the display module is configured to display the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information.

11. The ablation device according to claim 10, characterized in that: The blood pressure detection module is further configured to: collect fifth blood pressure data within each fourth preset time window during each ablation process and transmit it to the controller, and collect sixth blood pressure data within a fifth preset time window before each ablation and transmit it to the controller; The controller is also configured to: According to the first blood pressure data, obtaining preoperative systolic blood pressure information, preoperative diastolic blood pressure information, preoperative pulse pressure difference information and preoperative pulse information; Before each ablation, according to the sixth blood pressure data before the ablation, the pre-ablation systolic pressure information, the pre-ablation diastolic pressure information, the pre-ablation pulse pressure difference information, the pre-ablation pulse information and the pre-ablation dicrotic wave amplitude information corresponding to the ablation are obtained; After each ablation, according to the second blood pressure data after the ablation, the post-ablation systolic pressure information, the post-ablation diastolic pressure information, the post-ablation pulse pressure difference information and the post-ablation pulse information corresponding to the ablation are obtained, and according to the pre-ablation dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, the single ablation dicrotic wave amplitude decrease information corresponding to the ablation is obtained; In each ablation process, according to the fifth blood pressure data in each fourth preset time window in the ablation process, real-time systolic pressure information, real-time diastolic pressure information, real-time pulse pressure difference information, real-time pulse information and real-time dicrotic wave amplitude information are obtained, and according to the preoperative dicrotic wave amplitude information and the real-time dicrotic wave amplitude information, real-time dicrotic wave amplitude change information is obtained; The display module is further configured to provide a surgical interface and / or an ablation review interface; The surgical interface is configured to display the preoperative systolic pressure information, the preoperative diastolic pressure information, the preoperative pulse pressure difference information, the preoperative pulse information, the preoperative dicrotic wave amplitude information, the real-time systolic pressure information, the real-time diastolic pressure information, the real-time pulse pressure difference information, the real-time pulse information, and the real-time dicrotic wave amplitude information during each ablation process; The ablation review interface is configured as follows: after each ablation, the pre-ablation systolic pressure information, pre-ablation diastolic pressure information, pre-ablation pulse pressure difference information, pre-ablation pulse information, pre-ablation dicrotic wave amplitude information, post-ablation systolic pressure information, post-ablation diastolic pressure information, post-ablation pulse pressure difference information, post-ablation pulse information, post-ablation dicrotic wave amplitude information and single ablation dicrotic wave amplitude decrease information corresponding to the ablation are displayed.

12. A readable storage medium, characterized in that: The readable storage medium stores a computer program, and when the computer program is executed by the processor, the following steps are implemented: Acquiring preoperative dicrotic wave amplitude information according to first blood pressure data collected within a first preset time window before the operation; Controlling the energy generation module to provide ablation energy to the medical catheter to ablate the target blood vessel; After each ablation, the post-ablation dicrotic wave amplitude information corresponding to the ablation is obtained based on the second blood pressure data collected within a second preset time window after the ablation, and based on the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, it is determined whether it is necessary to continue ablation of the target blood vessel after the ablation.

13. The readable storage medium according to claim 12, characterized in that: The determining whether it is necessary to continue ablation of the target blood vessel after the ablation according to the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation includes: According to the preoperative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, the dicrotic wave amplitude change information corresponding to the ablation is obtained, and according to the dicrotic wave amplitude change information corresponding to the ablation, it is determined whether it is necessary to continue ablation of the target blood vessel after the ablation.

14. The readable storage medium according to claim 12, characterized in that: The step of obtaining the dicrotic wave amplitude change information corresponding to the ablation according to the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation includes: According to the pre-operative dicrotic wave amplitude information and the post-ablation dicrotic wave amplitude information corresponding to the ablation, obtaining the dicrotic wave amplitude reduction amount information or the dicrotic wave amplitude reduction percentage information corresponding to the ablation; The determining whether it is necessary to continue ablating the target blood vessel after the ablation according to the dicrotic wave amplitude change information corresponding to the ablation includes: If the decrease in the dicrotic wave amplitude corresponding to the ablation is less than the first preset amplitude, or the decrease in the dicrotic wave amplitude corresponding to the ablation is less than the first preset percentage, it is determined that the target blood vessel needs to be ablated further after the ablation, and the energy generation module is controlled to increase the output power to continue ablation at the ablation site corresponding to the ablation, or the operator is prompted to move the medical catheter to the next ablation site to continue ablation; If the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the percentage of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, it is determined that the target blood vessel needs to be continued to be ablated after the ablation, and the operator is prompted to move the medical catheter to the next ablation site to continue ablation or to a vicinity of the ablation site corresponding to the ablation to continue ablation; If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuates stably within the preset time after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuates stably within the preset time after the ablation, it is determined that there is no need to continue ablation of the target blood vessel; If the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset amplitude and the dicrotic wave fluctuation is unstable within the preset time after the ablation, or the decrease in the dicrotic wave amplitude corresponding to the ablation is greater than the second preset percentage and the dicrotic wave fluctuation is unstable within the preset time after the ablation, the operator is prompted to move the medical catheter to the next ablation site to continue ablation.

15. The readable storage medium according to claim 14, characterized in that: If the amount of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset amplitude and less than or equal to the second preset amplitude, or the percentage of decrease in the dicrotic wave amplitude corresponding to the ablation is greater than or equal to the first preset percentage and less than or equal to the second preset percentage, the energy generating module is controlled to provide stimulation energy to the medical catheter to stimulate the ablation site corresponding to the ablation. If the average value of the dicrotic wave amplitude during the stimulation process is greater than the average value of the dicrotic wave amplitude before stimulation, the operator is prompted to move the medical catheter to the vicinity of the ablation site corresponding to the ablation to continue the ablation.

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