Catheter

Abstract

The catheter comprises a catheter body, a plugging piece and an adjusting piece, spraying holes are formed in the side wall of the catheter body, the plugging piece is connected with the adjusting piece, the adjusting piece is arranged in the catheter body in a penetrating mode, and the adjusting piece is used for driving the plugging piece to move in the catheter body. According to the catheter, the blocking piece is driven by the adjusting piece to slide in the catheter body, so that the adjusting piece can control the position of the blocking piece in the catheter body, the effective liquid spraying length of the catheter can be controlled, and the situation that the effective liquid spraying length is too long, and liquid medicine is sprayed to non-diseased regions, so that blood vessels are damaged is avoided.

Description

Technical Field

[0001] The present application relates to the technical field of interventional medical devices, and in particular to a catheter. Background Art

[0002] This section merely provides background information related to the present disclosure and is not necessarily prior art.

[0003] Deep vein thrombosis of the lower extremities is a common and frequently occurring clinical disease. It can cause swelling and dysfunction of the affected limbs, and some can lead to serious complications such as pulmonary embolism, the latter of which has a high mortality rate. Currently, the main treatment for deep vein thrombosis of the lower extremities is to introduce a thrombolytic catheter and administer thrombolytic drugs such as urokinase for drug thrombolytic therapy. However, the existing thrombolytic catheter has a distal opening, which causes the thrombolytic solution to flow out of the distal opening, affecting the treatment effect.

[0004] In addition, the lengths of thrombi encountered during local thrombolysis are mostly different, and the drug spray length of existing thrombolytic catheters is fixed, which makes it impossible to spray drugs on thrombi in a targeted manner, resulting in drug waste and drug irritation damage to blood vessels without thrombi. At the same time, too much drug will increase the probability of bleeding complications. Summary of the invention

[0005] Based on this, it is necessary to provide a catheter, including a tube body, a sealing piece and an adjusting piece. The side wall of the tube body is provided with a spray hole. The sealing piece is connected to the adjusting piece. The adjusting piece is inserted into the tube body. The adjusting piece is used to drive the sealing piece to move in the tube body.

[0006] Optionally, the blocking member includes an elastomer, a side wall of the elastomer at least partially fits with an inner wall of the tube body, and the elastomer is connected to the adjusting member.

[0007] Optionally, the elastic body is in a semi-closed structure, the proximal end of the elastic body is provided with an opening, the opening is communicated with the lumen of the tube body, and the elastic body is suitable for expanding radially outward under pressure. Optionally, the elastic body includes a first state and a second state, when the elastic body is in the first state, at least part of the circumferential side wall of the elastic body at the maximum diameter is spaced from the inner wall of the tube body, and when the elastic body is in the second state, at least part of the side wall of the elastic body abuts against the inner wall of the tube body in the circumferential direction to achieve blocking.

[0008] Optionally, the elastic body includes a skeleton and a baffle film, the skeleton is connected to the adjusting member, the baffle film covers the side wall of the skeleton, and the baffle film and / or the skeleton are suitable for expanding toward both radial sides under the action of pressure.

[0009] Optionally, the skeleton includes a first braided wire and a second braided wire, the first braided wire and the second braided wire intersect to form a mesh structure, and the first braided wire and the second braided wire intersect and are movably connected.

[0010] Optionally, the skeleton includes a plurality of rod-shaped members, the plurality of rod-shaped members are arranged in a circumferential array along the adjusting member, and the rod-shaped members are arranged obliquely relative to the axis of the adjusting member.

[0011] Optionally, the baffle film is located radially outside the skeleton, and the baffle film is spaced apart from the skeleton at least when the blocking member is in the second state.

[0012] Optionally, the elastic body includes a cone section and a straight section, the distal end of the cone section is connected to the adjusting member, the other end of the cone section is connected to the straight section, and at least one annular protrusion structure is provided on the straight section.

[0013] Optionally, the elastomer includes a plurality of flow-blocking units, which are arranged around the adjusting member, the flow-blocking units are arranged obliquely relative to the axis of the adjusting member, two adjacent flow-blocking units at least partially overlap in the circumferential direction, and two adjacent flow-blocking units overlap in the radial direction.

[0014] Compared with the prior art, the catheter described in this application has the following beneficial effects:

[0015] The present application drives the blocking member to slide in the tube body through the adjusting member, so that the adjusting member can control the position of the blocking member in the tube body, thereby controlling the effective spray length of the catheter, avoiding excessive effective spray length and spraying liquid medicine on non-lesion areas to cause vascular damage. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 This is a schematic diagram of the structure of the catheter in Example 1 of the present application;

[0018] Figure 2 This is a schematic diagram of the structure of the spray hole in the first embodiment of the present application;

[0019] Figure 3 This is a structural schematic diagram of another implementation method of the spray hole in the first embodiment of the present application;

[0020] Figure 4 For this application Figure 1 A schematic diagram of the structure enlargement at point A;

[0021] Figure 5 This is a schematic diagram of the matching structure of the blocking member and the catheter in the first embodiment of the present application;

[0022] Figure 6 This is a schematic diagram of the matching structure of the blocking member and the catheter in the second embodiment of the present application;

[0023] Figure 7 This is a schematic diagram of the connection structure between the blocking member and the adjusting member in the second embodiment of the present application;

[0024] Figure 8 This is a schematic diagram of the structure in which the blocking member and the tube body are spaced apart in the second embodiment of the present application;

[0025] Fig. 9 This is a schematic diagram of the structure in which the plugging member and the tube body are fitted together in the second embodiment of the present application;

[0026] Fig.10 This is a schematic diagram of the connection structure between the skeleton and the coating in the second embodiment of the present application;

[0027] Fig.11 This is a schematic diagram of the connection structure of the first braided wire and the second braided wire in the second embodiment of the present application;

[0028] Fig.12 This is a schematic diagram of another connection structure of the first braided wire and the second braided wire in the second embodiment of the present application;

[0029] Fig.13 This is a schematic diagram of the structure of the skeleton in Example 2 of the present application;

[0030] Fig.14 This is a schematic diagram of another connection structure between the skeleton and the coating in the second embodiment of the present application;

[0031] Fig.15 This is a schematic diagram of the structure after the film is expanded in Example 2 of the present application;

[0032] Fig.16 This is a schematic diagram of another connection structure between the skeleton and the coating in the second embodiment of the present application;

[0033] Fig.17 This is a schematic diagram of the structure of the protrusion structure on the blocking member in the second embodiment of the present application;

[0034] Fig.18 This is a schematic diagram of the structure of the blocking member in the third embodiment of the present application;

[0035] Fig.19 This is a schematic structural diagram of the blocking member in Embodiment 3 of the present application from another perspective;

[0036] Fig. 20 This is a schematic diagram of the axial cross-sectional structure of the blocking member in the third embodiment of the present application;

[0037] Fig.21This is a schematic diagram of the radial cross-sectional structure of the blocking member in the third embodiment of the present application.

[0038] The reference numerals in the accompanying drawings are as follows:

[0039] 100 / 200 / 300, conduit; 110 / 210 / 310, tube body; 111, spray hole; 112, developing structure; 1121, first developing structure; 1122, second developing structure; 113, closing structure;

[0040] 120, blocking member; 121 / 220 / 320, elastic body; 122, connector; 221, opening; 224, connector; 222, skeleton; 2221, first braided wire; 2222, second braided wire; 2224, rod-shaped member;

[0041] 223, flow-blocking membrane; 2231, first end; 2232, second end; 2233, main body; 2234, linear object; 225, cone section; 226, straight section; 227, annular protrusion structure;

[0042] 321, flow blocking unit; 3211, first flow blocking unit; 3212, second flow blocking unit;

[0043] 130 / / 230 / 330, adjusting member; 131, first position; 132, second position. DETAILED DESCRIPTION

[0044] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present application, so the present application is not limited by the specific implementation disclosed below.

[0045] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0046] In the field of interventional medical devices, the "distal end" is usually defined as the end away from the operator during surgery, and the "proximal end" is defined as the end close to the operator during surgery.

[0047] Embodiment 1

[0048] This embodiment provides a catheter 100, which is used to intervene in a human body lumen to provide a delivery channel for implanting a device or delivering a drug. Figure 1As shown, the catheter 100 includes a tube body 110, and the tube body 110 is a tubular structure. The tube body 110 includes a proximal opening located at the axial proximal end and a distal opening located at the axial distal end, and the proximal opening and the distal opening are connected.

[0049] The side wall of the tube body 110 is provided with one or more spray holes 111, and the spray holes 111 are located at the distal end of the tube body 110, and the spray holes 111 are arranged toward the radial outer side of the tube body 110. In one embodiment, Figure 2 As shown, the side wall of the tube body 110 is provided with a plurality of spray holes 111, and the plurality of spray holes 111 are arranged along the axial direction of the tube body 110, and all the spray holes 111 are connected to the proximal opening of the tube body 110. In another embodiment, as Figure 3 As shown, a spray hole 111 is provided on the side wall of the tube body 110, and the spray hole 111 is arranged along the axial direction of the tube body 110, and the spray hole 111 can be in a strip structure or an elliptical structure. The proximal end of the tube body 110 is used to communicate with the injector, and the injector is used to inject fluid medicine into the tube body 110, and the fluid medicine flows from the proximal end to the distal end of the tube body 110, and the fluid medicine flows out from the inner side of the tube body 110 through the spray hole 111. The fluid medicine includes any one of urokinase, reteplase (rPA), tenecteplase (TNK-rPA), recombinant streptokinase, batroxobin, etc.

[0050] like Figure 2 , Figure 3 As shown, the tube body 110 includes two developing structures 112 that are spaced apart from each other, and the spray hole 111 is located between the two developing structures 112 .

[0051] The developing structure 112 includes a first developing structure 1121 and a second developing structure 1122, the first developing structure 1121 and the second developing structure 1122 are arranged at intervals, the first developing structure 1121 and the second developing structure 1122 are both located at the distal end of the tube body 110, the first developing structure 1121 is located at one end of the distal end, and the second developing structure 1122 is located at the other end of the distal end. The spray hole 111 is located between the first developing structure 1121 and the second developing structure 1122. The developing structure 112 is made of a radiopaque material, for example, the radiopaque material is any one or a combination of several materials of tantalum, platinum, and iridium. The developing structure 112 is an annular structure. The tube body 110 includes an inner membrane and an outer membrane arranged coaxially, and the developing structure 112 is located between the inner membrane and the outer membrane. During the use of the catheter 100, by arranging the spray hole 111 between the two developing structures 112, the doctor can identify the position of the spray hole 111 through the two developing structures 112, so as to facilitate the positioning of the spray hole 111 at the lesion position.

[0052] like Figure 4As shown, the catheter 100 also includes a blocking member 120 and an adjusting member 130. The blocking member 120 is connected to the adjusting member 130. The adjusting member 130 is passed through the tube body 110. The adjusting member 130 is used to drive the blocking member 120 to move in the tube body 110. The adjusting member 130 is used to drive the elastic body to move in the tube body 110.

[0053] The plugging piece 120 is made of an elastic material, for example, a nickel-titanium alloy material, a polyurethane material, etc. The plugging piece 120 can expand radially outward or contract radially inward after being acted upon by external pressure. When the plugging piece 120 is acted upon by pressure toward the center of the plugging piece 120, the plugging piece 120 is compressed. When the plugging piece 120 is acted upon by pressure toward the radial outward of the plugging piece 120, the plugging piece 120 expands radially outward. The plugging piece 120 is located on the inner side of the tube body 110. The plugging piece 120 fits against the inner wall of the tube body 110 and has a certain elastic force. The plugging piece 120 fits against the inner wall of the tube body 110 to form a blockage. The fluid in the tube body 110 is difficult to flow toward the distal opening of the tube body 110 due to the action of the plugging piece 120.

[0054] The blocking member 120 is connected to the adjusting member 130. The adjusting member 130 is inserted into the tube body 110. The adjusting member 130 is arranged along the axial direction of the tube body 110. One axial end of the adjusting member 130 passes through the proximal end of the tube body 110. The adjusting member 130 can slide axially in the tube body 110. The adjusting member 130 is used to drive the blocking member 120 to slide in the tube body to adjust the position of the blocking member 120 in the tube body 110 to control the effective length of the tube body 110 for infusing liquid to the outside. That is, the number of the spray holes 111 connected to the proximal opening of the tube body 110 or the communication area between the spray holes 111 and the proximal opening is controlled by adjusting the position of the blocking member 120. It can be understood that the more the number of the spray holes 111 connected to the proximal opening of the tube body 110 in the axial direction, or the larger the communication area between the spray holes 111 and the proximal opening, the longer the effective infusion length of the tube body 110.

[0055] like Figure 4 As shown, the blocking member 120 includes an elastic body 121 and a connecting body 122 . The elastic body 121 is connected to the connecting body 122 and is arranged around the connecting body 122 . The side wall of the elastic body 121 at least partially fits the inner wall of the tube body 110 . The connecting body 122 is connected to the adjusting member 130 .

[0056] The elastomer 121 is made of an elastic material, for example, the elastic material may be rubber, polyurethane (TPU, PCU, etc.), polyolefin thermoplastic elastomer (TPE), etc. The elastomer 121 is welded, bonded or threadedly connected to the connector 122. The elastomer 121 is arranged around the connector 122, and the elastomer 121 is at least partially located on the radial outside of the connector 122, and the outer diameter of the elastomer 121 is larger than the outer diameter of the connector 122. The elastomer 121 fits against the inner wall of the tube body 110. The connector 122 is made of a rigid material, for example, the rigid material may be: stainless steel or nickel-titanium alloy. An annular positioning groove is provided on the connector 122, and the elastomer 121 is located in the annular positioning groove, and the elastomer 121 fits against the inner wall of the annular positioning groove to achieve sealing.

[0057] In addition, the connector 122 is threadedly connected, welded or bonded to the adjusting member 130. For example, in one embodiment, a threaded hole is provided on the connector 122, and an external thread is provided on the adjusting member 130. The adjusting member 130 is inserted into the threaded hole and threadedly connected to the connector 122. The adjusting member 130 drives the elastic body 121 to move in the tube body 110 through the connector 122. In this way, during the bending process of the tube body 110, the elastic body 121 is connected to the connector 122. The connector 122 is made of a rigid material, so that the connector 122 can support the elastic body 121, preventing the elastic member from being deformed by the bending pressure of the tube body 110 and driving the adjusting member 130 to bend, thereby reducing the difficulty of pushing the elastic body 121 in the tube in a bent state.

[0058] For example, in one embodiment, Figure 5As shown, the plugging member 120 includes an axial first position 131 and an axial second position 132 within the tube body 110. Both the axial first position 131 and the axial second position 132 are located between the first imaging structure 1121 and the second imaging structure 1122. The axial first position 131 is located on the distal side of the axial second position 132. The distance between the axial first position 131 and the first imaging structure 1121 is x1, and the distance between the axial second position 132 and the first imaging structure 1121 is x2, where x2 > x1. When the plugging member 120 is at the axial first position 131, the effective liquid spraying length of the tube body is x1. At this time, the plugging member 120 plugs the spray holes 111 on the distal side of the plugging member 120. The spray holes 111 on the distal side of the plugging member 120 are not connected to the proximal opening, and the spray holes 111 on the proximal side of the plugging member 120 are connected to the proximal opening. The number of spray holes 111 connected to the proximal opening is smaller (i.e., compared with the number of spray holes 111 connected to the proximal opening when the plugging member 120 is in the second position 132) or the area of the spray holes 111 connected to the proximal opening is smaller (i.e., compared with the area of the spray holes 111 connected to the proximal opening when the plugging member 120 is in the second position 132). When the plugging member 120 is at the axial second position 132, the effective liquid spraying length of the tube body 110 is x2, where x2 < x1. At this time, the number of spray holes 111 connected to the proximal opening of the tube body 110 or the area of the spray holes connected to the proximal opening of the tube body 110 is smaller than the number or the connected area when the plugging member 120 is in the first position 131.

[0059] In this way, by driving the plugging member 120 to slide within the tube body 110 through the adjusting member 130, the adjusting member 130 can control the position of the plugging member 120 within the tube body 110, thereby controlling the effective liquid spraying length of the catheter 100 and avoiding blood vessel damage caused by excessive effective liquid spraying length to non-lesion sites when spraying the medicinal liquid.

[0060] As Figure 5 shown, the distal end of the tube body 110 has a converging structure 113. Specifically, the converging structure 113 means that the distal end of the tube body 110 has a certain taper, that is, the distal end of the tube body 110 has a conical structure, and the diameter of the conical structure decreases from the side close to the proximal end to the side close to the distal end. The maximum diameter of the converging structure 113 is smaller than the diameter of the plugging member 120. After the sealing member 120 moves towards the distal end to the converging structure 113, the converging structure 113 forms a stop for the plugging member 120 to prevent the plugging member 120 from passing through the distal end of the tube body 110.

[0061] Embodiment 2

[0062] The difference between this embodiment and Embodiment 1 is that, as Figure 6 、 Figure 7As shown, in the catheter 200, the elastic body 220 is in a cavity structure, and an opening 221 is provided at the proximal end of the elastic body 220, and the opening 221 is connected to the cavity structure. The elastic body 220 is suitable for expanding radially outward under the pressure of the fluid.

[0063] The elastomer 220 is sleeved on the adjusting member 230, one end of the elastomer 220 is connected to the adjusting member 230, the other end of the elastomer 220 is arranged toward the proximal end of the adjusting member 230, the distal end of the elastomer 220 is sealed, the proximal end of the elastomer 220 has an opening 221, and the opening 221 of the elastomer 220 is arranged toward the proximal end, and the side wall and the distal end of the elastomer 220 are enclosed to form a semi-closed structure.

[0064] It should be noted that the semi-enclosed structure refers to a cavity structure with a single-side opening 221. The side wall of the elastic body 220 has a certain elasticity. When the side wall of the elastic body 220 is subjected to pressure toward the center side of the tube body 210, the side wall of the elastic body 220 contracts toward the direction close to the adjusting member 230. When the side wall of the elastic body 220 is subjected to pressure toward the radially outer side of the tube body 210, the side wall of the elastic body 220 moves toward the direction away from the adjusting member 230.

[0065] It can be understood that in this embodiment, the elastic body 220 can be directly connected to the adjusting member 230, or can be connected to the adjusting member 230 through the connecting member 224. For example, in one embodiment, the connecting member 224 is an annular structure, the connecting member 224 is sleeved on the adjusting member 230 and fixedly connected to the adjusting member 230, and the distal end of the elastic body 220 is connected to the connecting member 224.

[0066] The elastic body 220 includes a first state and a second state, such as Figure 8 As shown, when the elastic body 220 is in the first state, the circumferential side wall of the radial cross section of the elastic body 220 at the maximum diameter is at least partially spaced from the inner wall of the tube body 210, as shown in FIG. Fig. 9 As shown, when the elastic body 220 is in the second state, the circumferential side wall of the radial cross section at the maximum diameter of the elastic body 220 is completely in contact with the inner wall of the tube body 210 to achieve fluid blocking. When the tube body 210 is not injected with liquid medicine, the elastic body 220 is in the first state. After the liquid medicine is injected into the tube body 210, the liquid medicine enters the cavity structure of the elastic body 220, and the liquid medicine forms an expansion force on the side wall of the elastic body 220, and the side wall of the elastic body 220 expands and fits with the inner wall of the tube body 210.

[0067] Before the liquid medicine is injected into the tube body 210, the elastic body 220 is in the first state, at which time, at least part of the largest diameter of the elastic body 220 is spaced from the inner wall of the tube body 210, and the elastic force between the elastic body 220 and the tube body 210 is small, so that it is convenient for the adjustment member 230 to drive the elastic body 220 to move in the tube body 210. After the adjustment member 230 drives the elastic body 220 to move to the target position, the liquid medicine is injected into the tube body 210, and the liquid medicine passes through the tube body 210 and enters the cavity structure of the elastic body 220. Under the pressure of the liquid medicine, the elastic body 220 expands toward both radial sides until the side wall of the largest diameter of the elastic body 220 is completely attached to the side wall of the tube body 210, so that the elastic body 220 blocks the liquid medicine, and the effective spray length of the tube body 210 is adjusted.

[0068] In this way, the elastic body 220 is in a cavity structure, and the side wall of the elastic body 220 is made of elastic material. During the process of perfusing the liquid medicine, the fluid accumulates in the cavity structure and forms a radially outward pressure on the side wall of the elastic body 220. The elastic body 220 can expand radially outward under the pressure of the fluid. On the one hand, the elastic body 220 can be self-adaptively blocked by the fluid pressure of the liquid medicine. On the other hand, the greater the fluid pressure on the elastic body 220, the stronger the elastic force between the elastic body 220 and the inner wall of the tube body 210, thereby increasing the stability of the elastic body 220 on the inner wall of the tube body 210. When the tube body 210 is not perfused with liquid medicine, the largest diameter of the elastic body 220 is at a certain distance from the tube body 210, so that the position of the tube body 210 can be adjusted or the elastic body 220 can be recovered.

[0069] like Fig.10 As shown, the elastic body 220 includes a skeleton 222 and a flow-blocking film 223. One end of the skeleton 222 is connected to the adjusting member 230, and the other end of the skeleton 222 is arranged toward the proximal end of the tube body 210. The circumferential side wall of the skeleton 222 is inclined relative to the center of the tube body 210 (such as Fig. 9 ), the proximal diameter of the skeleton 222 is greater than the distal diameter. It is understood that in other embodiments, the diameter of the skeleton 222 increases from the direction close to the proximal end to the direction close to the distal end. The flow-blocking film 223 is coated on the side wall of the skeleton 222. The flow-blocking film 223 and the skeleton 222 are surrounded to form a semi-enclosed structure. The flow-blocking film 223 forms a seal on the side wall of the skeleton 222. After the fluid enters the inner side of the skeleton 222, it is blocked by the flow-blocking film 223 and is difficult to pass through the elastic body 220, so that the fluid forms an expansion force on the skeleton 222 and the flow-blocking film 223 toward the radial outside.

[0070] like Fig.11As shown, the skeleton 222 includes a mesh structure, which can be formed by weaving braided wires or by heat setting a nickel-titanium metal tube after laser cutting, and the flow-blocking film 223 covers the side wall of the skeleton 222. The mesh structure is made of an elastic material, for example, the elastic material can be made of a nickel-titanium alloy material, a medical stainless steel wire or a xx material.

[0071] In one embodiment, if Fig.11 As shown, the first braided wire 2221 and the second braided wire 2222 only intersect but are not fixed, the first braided wire 2221 and the second braided wire 2222 are movably connected, and the first braided wire 2221 and the second braided wire 2222 can move relative to each other under the action of external force, so that the skeleton 222 can expand radially outward under the action of radially outward pressure. In another embodiment, as Fig.12 As shown, the mesh structure includes a first braided wire 2221 and a second braided wire 2222 . The first braided wire 2221 and the second braided wire 2222 intersect to form a mesh structure. The intersection 2223 of the first braided wire 2221 and the second braided wire 2222 is fixedly connected.

[0072] In another embodiment, if Fig.13 As shown, the skeleton 222 includes a frame structure, which includes a plurality of rod-shaped members 2224, one end of the rod-shaped member 2224 is connected to the connecting member 224, the other end of the rod-shaped member 2224 faces the proximal end of the pipe, the connecting member 224 is connected to the adjusting member 230, and the plurality of rod-shaped members 2224 are arranged along the circumference of the connecting member 224, the rod-shaped member 2224 is arranged obliquely relative to the axial direction of the pipe body 210, and the connecting member 224 and all the rod-shaped members 2224 form a tapered cylindrical structure as a whole. The flow-blocking film 223 is coated on the side wall of the rod-shaped member 2224, and the flow-blocking film 223, the rod-shaped member 2224 and the connecting member 224 are enclosed to form a semi-enclosed structure. It is understandable that the rod-shaped member 2224 can be hinged to the connecting member 224, or fixedly connected to the connecting member 224 and the rod-shaped member 2224 is made of elastic material, or other connection methods can be used to achieve the expansion of the rod-shaped member 2224 toward the radial outside under the fluid pressure of the flow-blocking membrane 223.

[0073] In this way, the baffle film 223 is wrapped around the side wall of the skeleton 222, so that the baffle film 223 can form a blockage on the inner side of the tube body 210, and then connected to the adjusting member 230 through one end of the skeleton 222, and the other end of the skeleton 222 is toward the proximal end of the tube body 210. The side wall of the skeleton 222 is inclined relative to the axial center of the tube body 210, so that the skeleton 222 and the baffle film 223 are surrounded to form a semi-closed structure, so that after the fluid enters the skeleton 222, the fluid forms an expansion force on the skeleton 222 and the baffle film 223 toward the radial outside.

[0074] like Fig.14As shown, the baffle film 223 is located on the outside of the skeleton 222, and the baffle film 223 is used to form a blockage on the outside of the skeleton 222. The baffle film 223 includes a first end 2231, a second end 2232 and a main body 2233. The first end 2231 is located at the distal end of the main body 2233, and the second end 2232 is located at the proximal end of the main body 2233. The first end 2231 is connected to the distal end of the skeleton 222, and the second end 2232 is connected to the proximal end of the skeleton 222. The main body 2233 is located between the first end 2231 and the second end 2232. There is no constraint force between the main body 2233 and the skeleton 222, or there is no constraint force before the main body 2233 expands radially outward to a certain diameter.

[0075] In this embodiment, the main body 2233 is not directly connected to the frame 222. For example, in one embodiment, Fig.14 As shown, one end of the flow-blocking film 223 is sewn to the distal end of the frame 222, and the second end 2232 of the flow-blocking film 223 is sewn to the proximal end of the frame 222. The main body 2233 is not directly connected to the frame 222, and the main body 2233 and the frame 222 have no adhesion or restraint. When the elastic body 220 is in the first state, the main body 2233 fits the frame 222. When the elastic body 220 is in the second state, as shown in FIG. Fig.15 As shown, the main body 2233 expands radially outward, and the main body 2233 is spaced apart from the skeleton 222. It is understood that in other embodiments, the first end 2231 and the second end 2232 of the flow-blocking film 223 can also be adhered to the skeleton 222. During the actual use of the catheter 200, after the elastic body 220 completes the adjustment of the effective infusion length, the drug solution is poured into the tube body 210. When the drug solution reaches the elastic body 220, it enters the inner side of the skeleton 222 and gathers in the elastic body 220 to generate fluid pressure to expand the flow-blocking film 223 to fit the side wall of the tube body 210. When the position of the elastic body 220 needs to be moved or the elastic body 220 needs to be withdrawn, the injection of liquid into the tube body 210 is stopped or the liquid in the tube body 210 is withdrawn. At this time, the flow-blocking film 223 loses the fluid pressure and fits on the skeleton 222, thereby facilitating the withdrawal of the elastic body 220.

[0076] In another embodiment, if Fig.16As shown, the main body 2233 is connected to the skeleton 222 through a thread 2234, and the length of the thread 2234 is greater than or equal to the difference between the maximum diameter of the skeleton 222 in the second state and the maximum diameter in the first state. The main body 2233 is located outside the skeleton 222, one end of the thread 2234 is connected to the main body 2233, and the other end of the thread 2234 is connected to the skeleton 222. The thread 2234 is flexible and made of a polymer material. For example, the thread 2234 can be a PTFE thread, a PET thread, or a surgical suture. When the skeleton 222 is in the second state, it is an expanded state. At this time, the side wall of the skeleton 222 is in contact with the inner wall of the tube body 210, and the maximum diameter of the skeleton 222 is d1. When the skeleton 222 is in the first state, it is a contracted state. At this time, at least part of the maximum diameter of the skeleton 222 is spaced from the inner wall of the tube body 210, and the maximum diameter of the skeleton 222 is d2. The length L of the thread 2234 is greater than d1-d2. Thus, the main body 2233 is connected to the skeleton 222 through the thread 2234, and the length of the thread 2234 is greater than the difference between the maximum diameter of the skeleton 222 in the second state and the maximum diameter in the first state, so that the thread 2234 can provide a certain margin for the movement of the main body 2233 toward the radial outside. After the main body 2233 is subjected to the pressure of the fluid, the main body 2233 can expand toward the radial outside within the length of the thread 2234, thereby achieving the blocking of the tube body 210.

[0077] In this way, the first end 2231 and the second end 2232 of the flow-blocking membrane 223 are connected to the skeleton 222, and the main body 2233 is not connected to the skeleton 222 or is connected through a linear object 2234, so that the main body 2233 forms a free section on the skeleton 222, that is, there is no restraint or there is no restraint within a certain diameter range, so that the main body 2233 can be freely expanded under the action of fluid pressure to form a blockage in the tube body 210.

[0078] like Fig.17As shown, the elastic body 220 includes a connected cone section 225 and a straight section 226, one end (specifically the distal end) of the cone section 225 is connected to the adjusting member 230, and the other end of the cone section 225 is connected to the straight section 226. The diameter of the distal end of the cone section 225 is smaller than the diameter of the proximal end, and the diameter of the cone section 225 increases from the proximal end to the distal end. The maximum diameter of the cone section 225 is the proximal end of the cone section. The distal end of the cone section 225 is connected to the adjusting member 230, and the proximal end of the cone section 225 is connected to the straight section 226. The side wall of the cone section 225 is inclined relative to the axis of the tube body 210, and the side wall of the cone section 225 is inclined toward the radial outer side of the tube body 210. The straight section 226 is connected to the proximal end of the cone section 225, and the straight section 226 is arranged along the axial direction of the tube body 210. When the elastic body 220 is in the first state, the proximal end of the cone section 225 and the straight section 226 are at least partially spaced from the inner wall of the tube body 210 in the circumferential direction. When the elastic body 220 is in the second state, the straight section 226 is at least partially fitted with the inner wall of the tube body 210, and the cone section 225 is at least partially fitted with the inner wall of the tube body 210.

[0079] Therefore, the elastomer 220 includes a conical section 225 and a straight section 226, the proximal end of the conical section 225 is connected to the adjusting member 230, and the distal end of the conical section 225 is connected to the straight section 226, so that the straight section 226 extends toward the proximal side at the proximal end of the conical section 225, so that when the elastomer 220 is in the second state, the skeleton 222 can form a surface contact with the tube body 210, thereby increasing the sealing stability of the elastomer 220.

[0080] like Fig.17 As shown, a plurality of annular protrusion structures 227 are provided on the straight section 226, and the plurality of annular protrusion structures 227 are arranged along the axial direction of the straight section 226. The annular protrusion structure 227 protrudes toward the radial outer side of the tube body 210, and the convex surface of the annular protrusion structure 227 is arranged toward the radial outer side of the tube body 210. The annular protrusion structure 227 can be formed by heat setting after the skeleton 222 protrudes toward the radial outer side, or by stacking the flow-blocking film 223 at the protruding position. It should be noted that the stacking of the flow-blocking film 223 means that the flow-blocking film 223 is formed by folding multiple layers and then being fixed by sewing or hot-melt bonding. In this way, by providing a plurality of annular protrusion structures 227 on the straight section 226 and axially arranging the plurality of annular protrusion structures 227 along the straight section 226, after the elastomer 220 expands, the annular protrusion structures 227 can increase the friction between the elastomer 220 and the inner wall of the tube body 210, thereby increasing the position stability of the elastomer 220 in the tube body 210.

[0081] Embodiment 3

[0082] The difference between this embodiment and the first embodiment is that Fig.18 , Fig.19As shown, in the catheter 300, the elastomer 320 includes a plurality of flow-blocking units 321, one end of the flow-blocking unit 321 is connected to the adjusting member 330, the flow-blocking unit 321 is inclined relative to the axis of the adjusting member 330, and the plurality of flow-blocking units 321 are arranged around the adjusting member 330, and two adjacent flow-blocking units 321 at least partially overlap in the circumferential direction, and all the flow-blocking units 321 enclose a cavity structure, and two adjacent flow-blocking units 321 are staggered in the radial direction.

[0083] The distal end of the flow blocking unit 321 is connected to the adjusting member 330, the proximal end of the flow blocking unit 321 is a free end and extends toward the proximal end of the tube body 310, the proximal end of the flow blocking unit 321 is spaced apart from the adjusting member 330, and the flow blocking unit 321 is tilted relative to the axis of the adjusting member 330. In the axial section of the flow blocking unit 321, the side wall of the flow blocking unit 321 is a linear structure or an arc structure. When the side wall of the flow blocking unit 321 is a linear structure, the proximal end and the distal end of the side wall of the axial section of the flow blocking unit 321 are located on the same straight line. Fig. 20 As shown, when the side wall of the flow blocking unit 321 is in an arc-shaped structure, the side wall of the flow blocking unit 321 protrudes toward the radial outer side of the tube body 310, and the convex surface of the side wall of the axial section of the flow blocking unit 321 is arranged toward the radial outer side of the tube body 310. It can be understood that in other embodiments, when the side wall of the flow blocking unit 321 is in an arc-shaped structure, the side wall of the flow blocking unit 321 protrudes toward the center of the tube body 310, and the convex surface of the side wall of the flow blocking unit 321 is arranged toward the center of the tube body 310 in the axial section of the flow blocking unit 321. The flow blocking unit 321 is made of elastic material. After the flow blocking unit 321 is subjected to the pressure of the fluid, the free end of the flow blocking unit 321 moves toward the radial outer side of the tube body 310 until the free end of the flow blocking unit 321 fits with the side wall of the tube body 310, and the elastic body 320 is in the second state. When the flow blocking unit 321 is not affected by the pressure of the fluid, at least a portion of the free end of the flow blocking unit 321 is spaced apart from the free end of the tube body 310 . At this time, the elastic body 320 is in the first state.

[0084] A plurality of flow-blocking units 321 are arranged around the adjusting member 330, and a plurality of flow-blocking units 321 are arranged in a circumferential array along the adjusting member 330, and a plurality of flow-blocking units 321 overlap at least partially in the circumferential direction, and a plurality of flow-blocking units 321 are enclosed to form a semi-enclosed structure, that is, a plurality of flow-blocking units 321 are enclosed to form a cavity structure, and an opening is formed at the proximal end of the cavity structure, and the opening is connected to the cavity structure, and the cavity structure can accommodate a fluid. Two adjacent flow-blocking units 321 are staggered in the radial direction. It should be noted that two adjacent flow-blocking units 321 are staggered in the radial direction, which means that, on the radial section of the elastic body 320, the distances between the two adjacent flow-blocking units 321 and the center of the elastic body 320 are different so that the two adjacent flow-blocking units 321 overlap in the radial direction, so that the movement of the two adjacent flow-blocking units 321 in the circumferential direction does not interfere with each other.

[0085] For example, in one embodiment, Fig.21 As shown, two adjacent flow-blocking units 321 include a first flow-blocking unit 3211 and a second flow-blocking unit 3212, the first flow-blocking unit 3211 is located radially outside the second flow-blocking unit 3212, and the first flow-blocking unit 3211 and the second flow-blocking unit 3212 overlap at least partially in the circumferential direction. The inner wall of the first flow-blocking unit 3211 fits the outer wall of the second flow-blocking unit 3212. The distance between the inner wall of the first flow-blocking unit 3211 and the center of the elastic body 320 is x1, and the distance between the inner wall of the second flow-blocking unit 3212 and the center of the elastic body 320 is x2, x1 is greater than x2, and the wall thickness of the flow-blocking unit 321 is d=x1-x2.

[0086] In the actual use of the tube body 310, before the liquid medicine is injected into the tube body 310, the elastic body 320 is in the first state, at this time, the proximal end of at least part of the flow blocking unit 321 is spaced from the inner wall of the tube body 310, and the force between the flow blocking unit 321 and the inner wall of the tube body 310 is small, so that the elastic body 320 is easy to move in the tube body 310. After the adjustment member 330 drives the elastic body 320 to move to the target position, the liquid medicine is injected into the tube body 310, and the liquid medicine passes through the tube body 310 into the cavity structure enclosed by the multiple flow blocking units 321. Under the pressure of the liquid medicine, the multiple flow blocking units 321 expand toward both sides of the radial direction until the proximal end of the flow blocking unit 321 is attached to the side wall of the tube body 310, so that the elastic body 320 forms a blockage on the liquid medicine, and the effective spray length of the tube body 310 is adjusted.

[0087] In this way, by circumferentially arranging a plurality of flow-blocking units 321 around the adjusting member 330, two adjacent flow-blocking units 321 overlap in the circumferential direction so that all the flow-blocking units 321 are enclosed to form a cavity structure, and by radially staggering two adjacent flow-blocking units 321, the two adjacent flow-blocking units 321 will not interfere with each other during the expansion process, thereby facilitating the flow-blocking units 321 to open under the pressure of the fluid to achieve sealing.

[0088] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0089] The above-mentioned embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the attached claims.

Claims

1. A catheter, characterized in that: It includes a tube body, a plugging piece and an adjusting piece. The side wall of the tube body is provided with a spray hole. The plugging piece is connected to the adjusting piece. The adjusting piece is inserted into the tube body and is used to drive the plugging piece to move in the tube body.

2. The catheter according to claim 1, characterized in that The blocking member includes an elastic body, a side wall of the elastic body at least partially fits with the inner wall of the tube body, and the elastic body is connected to the adjusting member.

3. The catheter according to claim 2, characterized in that The elastic body is in a semi-closed structure, and an opening is formed at the proximal end of the elastic body, the opening is communicated with the lumen of the tube body, and the elastic body is suitable for expanding radially outward under the action of pressure.

4. The catheter according to claim 3, characterized in that The elastomer includes a first state and a second state. When the elastomer is in the first state, the circumferential side wall of the elastomer at the largest diameter is at least partially spaced from the inner wall of the tube body. When the elastomer is in the second state, at least part of the side wall of the elastomer abuts against the inner wall of the tube body in the circumferential direction to achieve sealing.

5. The catheter according to claim 2, characterized in that The elastic body comprises a skeleton and a baffle film, the skeleton is connected to the adjusting member, the baffle film covers the side wall of the skeleton, and the baffle film and / or the skeleton are suitable for expanding toward both radial sides under the action of pressure.

6. The catheter according to claim 5, characterized in that The skeleton includes a first braided wire and a second braided wire, wherein the first braided wire and the second braided wire intersect to form a mesh structure, and the first braided wire and the second braided wire intersect and are movably connected.

7. The catheter according to claim 5, characterized in that The skeleton comprises a plurality of rod-shaped members, which are arranged in a circumferential array along the adjusting member, and the rod-shaped members are arranged obliquely relative to the axis of the adjusting member.

8. The catheter according to claim 5, characterized in that The flow-blocking film is located on the radially outer side of the frame, and the flow-blocking film is spaced apart from the frame at least when the blocking member is in the second state.

9. The catheter according to claim 2, characterized in that The elastic body comprises a cone section and a straight section, the distal end of the cone section is connected to the adjusting member, the other end of the cone section is connected to the straight section, and at least one annular protrusion structure is provided on the straight section.

10. The catheter according to claim 2, characterized in that The elastic body includes a plurality of flow-blocking units, which are arranged around the adjusting member, the flow-blocking units are arranged obliquely relative to the axis of the adjusting member, two adjacent flow-blocking units at least partially overlap in the circumferential direction, and two adjacent flow-blocking units overlap in the radial direction.

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