Nano crushing and grinding device for biological agent

Abstract

The nanometer smashing and grinding device comprises a base and further comprises a driving assembly, a supporting frame is fixedly connected to the top of the base, a nanometer smashing and grinding machine is fixedly connected to the top of the supporting frame, and a working box is fixedly connected to the right side of the top of the base; a fixed circular plate is fixedly connected to the position, close to the bottom, in the working box, the driving assembly comprises a driving motor, the driving motor is fixedly connected to the middle of the bottom in the working box and provided with an output shaft, the top of the output shaft of the driving motor is fixedly connected with a middle shaft rotating cylinder, and the top of the fixed circular plate is fixedly connected with a screening basket; the top of the middle shaft rotating cylinder is fixedly connected with a motor box. According to the device, when the rotary connecting rod drives the grinding ball to rotate, centrifugal force is generated on the rotary connecting rod, the first knocking head moves and knocks the inner wall of the grinding ball for multiple times, caked powder attached to the outer wall of the grinding ball can be knocked off, and the smashing effect is better when the device is used.

Description

Technical Field

[0001] The invention relates to the technical field of biological preparation processing equipment, in particular to a nano-crushing and grinding device for biological preparations. Background Art

[0002] Biologics are highly active polypeptide immune preparations extracted using genetic bioengineering technology. Generally speaking, they refer to some special antibodies or recombinant products of natural inhibitors of the body's immune and inflammatory regulatory molecules. Nano-crushing and grinding can reduce the particle size of biologics, thereby reducing their irritation in the body and reducing the occurrence of side effects. This is of great significance for improving patients' treatment experience and comfort.

[0003] A Chinese patent application with patent application number CN202111194798.4 discloses a grinding device for the production of biological agents. Although the application achieves uniform grinding of raw materials and enables rapid discharge of raw materials after grinding, when the application is implemented, the ground powder accumulates on the drying plate, and the internal temperature of the grinder rises when working. At the same time, the internal air is relatively humid. In a high temperature and high humidity environment, it is easy for caking and adhesion to form on the outside of the hammer head, which leads to a decrease in the overall grinding efficiency. Improvements are needed to address this problem. Summary of the invention

[0004] The object of the present invention is to provide a nano-crushing and grinding device for biological preparations to solve the problems raised in the above-mentioned background technology.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions: a nano-crushing and grinding device for biological preparations, comprising a base and a driving assembly, wherein a support frame is fixedly connected to the top of the base, a nano-crushing and grinding machine is fixedly connected to the top of the support frame, a working box is fixedly connected to the right side of the top of the base, and a fixed circular plate is fixedly connected to the working box near the bottom.

[0006] Wherein, the driving component comprises:

[0007] The driving motor is fixedly connected to the middle of the bottom of the working box. The driving motor has an output shaft. The top of the driving motor output shaft is fixedly connected to the middle axis rotating cylinder. The top of the fixed circular plate is fixedly connected to the screening basket. The top of the middle axis rotating cylinder is fixedly connected to the motor box. The bottom of the motor box is fixedly connected to the driving motor. The driving motor has an output shaft. The bottom of the driving motor output shaft is fixedly connected to the lifting screw. The driving motor can drive the middle axis rotating cylinder to rotate when working.

[0008] According to the above technical scheme, it also includes a grinding assembly, which consists of a ball nut pair moving seat, a fixed ring block, a supporting protective sleeve, a lifting drive frame, a rotating connecting rod, a grinding ball, a fixed extension block, a spring, a knocking head and a guide slide rod.

[0009] The moving seat of the ball nut pair is threadedly connected to the outside of the lifting screw, the fixed annular block is fixedly connected to the top of the moving seat of the ball nut pair, the supporting protective sleeve is fixedly connected to the outside of the fixed annular block, the lifting drive frame is fixedly connected to the outside of the supporting protective sleeve, the rotating connecting rod is rotatably connected to the middle part of the lifting drive frame, the grinding ball is rotatably connected to the end of the rotating connecting rod away from the lifting drive frame, the fixed extension block is fixedly connected to the end of the grinding ball away from the rotating connecting rod, the spring 1 is fixedly connected to the outside of the fixed extension block, the knocking head 1 is fixedly connected to the other end of the spring 1, the guide slide rod is fixedly connected to the outside of the fixed extension block, and the grinding ball can rotate on the outside of the rotating connecting rod.

[0010] According to the above technical solution, it also includes a knocking component, which consists of an elliptical disc, a positioning plate, a second spring, a force plate, an air storage cylinder, a piston movable frame, a knocking base, a knocking box, a third spring, a piston plate, a second knocking head and an air connecting pipe.

[0011] The elliptical disc is fixedly connected to the outside of the output shaft of the driving motor, the positioning plate is fixedly connected to the top of the fixed circular plate, the second spring is fixedly connected to the side of the positioning plate close to the elliptical disc, the force plate is fixedly connected to the end of the second spring away from the positioning plate, the air storage cylinder is fixedly connected to the side of the positioning plate away from the elliptical disc, the piston moving frame is fixedly connected to the middle of the side of the force plate away from the driving motor, the knocking base is fixedly connected to the outside of the top of the fixed circular plate, the knocking box is fixedly connected to the top of the knocking base, the third spring is fixedly connected to the bottom of the knocking box, the piston plate is fixedly connected to the top of the third spring, the second knocking head is fixedly connected to the top of the piston plate, and the air connecting pipe is fixedly connected to the middle of the outside of the air storage cylinder. The elliptical disc rotates with the driving motor, so that the elliptical disc can squeeze the force plate.

[0012] According to the above technical solution, the output shaft of the driving motor passes through the middle of the fixed circular plate and extends to the top of the fixed circular plate and is fixedly connected to the bottom of the central axis rotating cylinder. A fixed disc is fixedly connected inside the lifting screw. The bottom of the lifting screw is rotatably connected to the top of the fixed disc, which can support the lifting screw.

[0013] According to the above technical solution, a lifting groove is provided on the outside of the central axis rotating cylinder to accommodate the lifting and lowering of the ball nut pair moving seat, and a guide groove is provided on the bottom of the ball nut pair moving seat. The ball nut pair moving seat is slidably connected to the outer wall of the central axis rotating cylinder through the guide groove, so that the ball nut pair moving seat can be lifted and lowered on the outside of the central axis rotating cylinder.

[0014] According to the above technical solution, a guide circular groove is opened in the striking head, and the striking head is slidably connected to the outer wall of the guide slide rod through the guide circular groove. A limiting disc is provided at one end of the guide slide rod away from the fixed extension block, and the striking head can be guided and moved outside the guide slide rod.

[0015] According to the above technical solution, the air connecting pipe is fixedly connected to the outer bottom of the knocking box at one end away from the air cylinder, the inside of the air cylinder is connected to the inner bottom of the knocking box through the air connecting pipe, the piston moving frame is slidably connected to the inner wall of the air cylinder, the piston plate is slidably connected to the inner wall of the knocking box, the top end of the second knocking head passes through the top of the knocking box and extends to above the knocking box, and the second knocking head can knock on the bottom of the screening basket.

[0016] According to the above technical solution, as described.

[0017] Compared with the prior art, the beneficial effects achieved by the present invention are:

[0018] 1. After the grinding work is completed by the nano-crushing grinder, the powder produced by the grinding in the nano-crushing grinder falls into the working box. At this time, the driving motor is controlled to work, so that the grinding balls continue to move in a circle at the bottom of the screening basket, and the accumulated powder is crushed at the same time, so that the powder can be ground multiple times, and at the same time, the crushed powder can be ground for the second time, so that the size difference of the powder is small;

[0019] 2. When the rotating connecting rod drives the grinding ball to rotate, centrifugal force is generated on the rotating connecting rod, so that the knocking head moves and knocks the inner wall of the grinding ball multiple times, which can knock off the agglomerated powder adhering to the outer wall of the grinding ball, so that the crushing effect of the device is better when it is used;

[0020] 3. When the driving motor rotates, the output shaft of the driving motor drives the elliptical disc to rotate, so that the knocking head knocks the bottom of the screening basket, so that the device can drop the powder adhered to the filter holes of the screening basket when in use, ensuring the stability of material discharge;

[0021] 4. When the position of the grinding balls needs to be adjusted, the driving motor is controlled to work so that the position of the grinding balls on the central axis rotating cylinder can be adjusted. At the same time, the grinding balls can continuously abut against the bottom of the screening basket so that the grinding position of the grinding balls on the powder can be adjusted. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0023] Figure 1It is a schematic diagram of the overall structure of the present invention;

[0024] Figure 2 It is a schematic diagram of the interior of the nano-crushing grinder of the present invention;

[0025] Figure 3 It is a schematic diagram of the interior of the working box of the present invention;

[0026] Figure 4 is a schematic diagram of a driving motor of the present invention;

[0027] Figure 5 is a schematic diagram of the interior of a screening basket of the present invention;

[0028] Figure 6 It is a schematic diagram of an explosion at a fixed circular ring block of the present invention;

[0029] Figure 7 is a schematic diagram of the interior of the grinding ball of the present invention;

[0030] Figure 8 yes Figure 7 The enlarged schematic diagram at A in the middle;

[0031] Fig. 9 It is a schematic diagram of the elliptical disk of the present invention;

[0032] Fig.10 It is a schematic diagram of the piston moving frame of the present invention.

[0033] In the figure: 1, base; 2, support frame; 3, nano-crushing grinder; 4, working box; 5, fixed circular plate; 6, driving assembly; 601, driving motor; 602, screening basket; 603, central axis rotating cylinder; 604, motor box; 605, driving motor; 606, lifting screw; 7, grinding assembly; 701, ball nut pair moving seat; 702, fixed circular ring block; 703, supporting protective cover; 704, lifting driving frame; 705, rotating connection Rod; 706, grinding ball; 707, fixed extension block; 708, spring one; 709, knocking head one; 710, guide slide rod; 8, knocking assembly; 801, elliptical disk; 802, positioning plate; 803, spring two; 804, force plate; 805, air cylinder; 806, piston moving frame; 807, knocking base; 808, knocking box; 809, spring three; 810, piston plate; 811, knocking head two; 812, air connecting pipe. DETAILED DESCRIPTION

[0034] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0035] Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0036] For example, see Figure 1-7 The present invention provides a technical solution: a nano-crushing and grinding device for biological preparations, including a base 1 and a driving assembly 6. A support frame 2 is fixedly connected to the top of the base 1, a nano-crushing and grinding machine 3 is fixedly connected to the top of the support frame 2, a working box 4 is fixedly connected to the right side of the top of the base 1, and a fixed circular plate 5 is fixedly connected near the bottom of the working box 4.

[0037] Wherein, the driving component 6 comprises:

[0038] The driving motor 601 is fixedly connected to the middle of the bottom of the working box 4. The driving motor 601 has an output shaft. The top of the output shaft of the driving motor 601 is fixedly connected to the central axis rotating cylinder 603. The top of the fixed circular plate 5 is fixedly connected to the screening basket 602. The top of the central axis rotating cylinder 603 is fixedly connected to the motor box 604. The bottom of the motor box 604 is fixedly connected to the driving motor 605. The driving motor 605 has an output shaft. The bottom of the output shaft of the driving motor 605 is fixedly connected to the lifting screw 606. The driving motor 601 can drive the central axis rotating cylinder 603 to rotate when working.

[0039] It also includes a grinding assembly 7, which consists of a ball nut pair moving seat 701, a fixed ring block 702, a supporting protective sleeve 703, a lifting drive frame 704, a rotating connecting rod 705, a grinding ball 706, a fixed extension block 707, a spring 708, a knocking head 709 and a guide slide rod 710.

[0040] The ball nut pair moving seat 701 is threadedly connected to the outside of the lifting screw 606, the fixed ring block 702 is fixedly connected to the top of the ball nut pair moving seat 701, the support and protective sleeve 703 is fixedly connected to the outside of the fixed ring block 702, the lifting drive frame 704 is fixedly connected to the outside of the support and protective sleeve 703, the rotating connecting rod 705 is rotatably connected to the middle part of the lifting drive frame 704, the grinding ball 706 is rotatably connected to the end of the rotating connecting rod 705 away from the lifting drive frame 704, the fixed extension block 707 is fixedly connected to the end of the grinding ball 706 away from the rotating connecting rod 705, the spring 1 708 is fixedly connected to the outside of the fixed extension block 707, the knocking head 1 709 is fixedly connected to the other end of the spring 1 708, the guide slide rod 710 is fixedly connected to the outside of the fixed extension block 707, and the grinding ball 706 can rotate on the outside of the rotating connecting rod 705.

[0041] The output shaft of the driving motor 601 passes through the middle of the fixed circular plate 5 and extends to the top of the fixed circular plate 5 and is fixedly connected to the bottom of the central axis rotating cylinder 603. The lifting screw 606 is fixedly connected to a fixed disc inside. The bottom of the lifting screw 606 is rotatably connected to the top of the fixed disc, which can support the lifting screw 606.

[0042] A lifting groove is provided on the outside of the central axis rotating cylinder 603 to accommodate the lifting and lowering of the ball nut pair moving seat 701. A guide groove is provided on the bottom of the ball nut pair moving seat 701. The ball nut pair moving seat 701 is slidably connected to the outer wall of the central axis rotating cylinder 603 through the guide groove, so that the ball nut pair moving seat 701 can be lifted and lowered on the outside of the central axis rotating cylinder 603.

[0043] A guide circular groove is provided in the striking head 709, and the striking head 709 is slidably connected to the outer wall of the guide slide rod 710 through the guide circular groove. A limiting disc is provided at one end of the guide slide rod 710 away from the fixed extension block 707, so that the striking head 709 can be guided and moved outside the guide slide rod 710.

[0044] For example 2, please refer to Figure 1-10 On the basis of the first embodiment, the present invention provides a technical solution: it also includes a knocking component 8, which is composed of an elliptical disc 801, a positioning plate 802, a second spring 803, a force plate 804, an air storage cylinder 805, a piston moving frame 806, a knocking base 807, a knocking box 808, a third spring 809, a piston plate 810, a second knocking head 811 and an air connecting pipe 812.

[0045] The elliptical disc 801 is fixedly connected to the outer side of the output shaft of the driving motor 601, the positioning plate 802 is fixedly connected to the top of the fixed circular plate 5, the second spring 803 is fixedly connected to the side of the positioning plate 802 close to the elliptical disc 801, the force plate 804 is fixedly connected to the end of the second spring 803 away from the positioning plate 802, the air storage cylinder 805 is fixedly connected to the side of the positioning plate 802 away from the elliptical disc 801, the piston moving frame 806 is fixedly connected to the middle of the force plate 804 away from the driving motor 601, and the bottom is knocked. The seat 807 is fixedly connected to the outer side of the top of the fixed circular plate 5, the knocking box 808 is fixedly connected to the top of the knocking base 807, the spring three 809 is fixedly connected to the inner bottom of the knocking box 808, the piston plate 810 is fixedly connected to the top of the spring three 809, the knocking head two 811 is fixedly connected to the top of the piston plate 810, and the air connecting pipe 812 is fixedly connected to the middle part of the outer side of the air storage cylinder 805. The elliptical disk 801 rotates with the driving motor 601, so that the elliptical disk 801 can squeeze the force plate 804.

[0046] The air connecting pipe 812 is fixedly connected to the outer bottom of the knocking box 808 at one end away from the air cylinder 805, the interior of the air cylinder 805 is connected to the inner bottom of the knocking box 808 through the air connecting pipe 812, the piston moving frame 806 is slidably connected to the inner wall of the air cylinder 805, the piston plate 810 is slidably connected to the inner wall of the knocking box 808, the top of the knocking head 811 penetrates the top of the knocking box 808 and extends to the top of the knocking box 808, and the knocking head 811 can knock on the bottom of the screening basket 602.

[0047] After the grinding work by the nano-crushing grinder 3 is completed, the powder produced by the grinding in the nano-crushing grinder 3 falls into the working box 4. At this time, the powder is accumulated at the bottom of the screening basket 602. At this time, the driving motor 601 is controlled to work, so that the driving motor 601 drives the central axis rotating cylinder 603 to rotate during operation, so that the central axis rotating cylinder 603 can drive the grinding balls 706 to move at the bottom of the screening basket 602 by rotating the connecting rod 705. At this time, the grinding balls 706 rotate outside the rotating connecting rod 705, so that the grinding balls 706 continue to perform circular motion at the bottom of the screening basket 602, so that the grinding balls 706 crush the powder accumulated at the bottom of the screening basket 602, so that the powder can be ground multiple times, and at the same time, it is ensured that the crushed powder can be ground for the second time, and the size difference of the powder is small.

[0048] When the rotating connecting rod 705 drives the grinding ball 706 to rotate, centrifugal force is generated on the rotating connecting rod 705. At the same time, under the action of the centrifugal force, the spring 708 is stretched, and the knocking head 709 slides on the guide slide rod 710. At the same time, after the knocking head 709 moves, the knocking head 709 knocks the inner wall of the grinding ball 706, causing vibration on the inner wall of the grinding ball 706. After the knocking head 709 knocks the inner wall of the grinding ball 706, the knocking head 709 rebounds, which can compress the spring 708. As the spring 708 recovers elastically, the knocking head 709 moves and knocks the inner wall of the grinding ball 706 for the second time. When knocking inside the grinding ball 706, the agglomerated powder adhering to the outer wall of the grinding ball 706 can be knocked off, so that the device has a better crushing effect when used.

[0049] When the driving motor 601 rotates, the output shaft of the driving motor 601 drives the elliptical disc 801 to rotate, and when the elliptical disc 801 rotates, the elliptical disc 801 squeezes the force plate 804, so that the spring 2 803 is compressed, and at the same time the force plate 804 pushes the piston moving frame 806, so that the piston moving frame 806 moves in the air cylinder 805, and the air in the air cylinder 805 moves to the knocking box 808 through the air connecting pipe 812, so that the pressure at the bottom of the knocking box 808 increases, and the spring 3 809 is stretched, and at the same time the knocking head 2 811 on the piston plate 810 knocks on the bottom of the screening basket 602, so that the device can drop the powder adhered to the filter holes of the screening basket 602 when in use, thereby ensuring stability during material discharge.

[0050] When the position of the grinding ball 706 needs to be adjusted, the driving motor 605 is controlled to work, so that the driving motor 605 drives the lifting screw 606 to rotate, and the lifting screw 606 rotates, and the ball nut pair moving seat 701 is lifted and lowered on the outside of the lifting screw 606, so that the rotating connecting rod 705 in the middle of the lifting driving frame 704 rotates, so that the grinding ball 706 can continue to abut against the bottom inner wall of the screening basket 602, and at the same time, the driving motor 601 works, so that the driving motor 601 controls the central axis rotating cylinder 603 to rotate during operation, and at the same time drives the rotating connecting rod 705 and the grinding ball 706 to rotate in the screening basket 602, and at the same time enables the device to adjust the position of the grinding ball 706 on the central axis rotating cylinder 603.

[0051] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0052] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A nano-crushing and grinding device for biological preparations, comprising a base (1), characterized in that: It also comprises a driving assembly (6), wherein the top of the base (1) is fixedly connected to a support frame (2), the top of the support frame (2) is fixedly connected to a nano-crushing grinder (3), the top right side of the base (1) is fixedly connected to a working box (4), and a fixed circular plate (5) is fixedly connected to the inside of the working box (4) near the bottom; Wherein, the driving component (6) comprises: A driving motor (601) is fixedly connected to the middle of the bottom of the working box (4). The driving motor (601) has an output shaft. The top of the output shaft of the driving motor (601) is fixedly connected to a central axis rotating cylinder (603). The top of the fixed circular plate (5) is fixedly connected to a screening basket (602). The top of the central axis rotating cylinder (603) is fixedly connected to a motor box (604). The bottom of the motor box (604) is fixedly connected to a driving motor (605). The driving motor (605) has an output shaft. The bottom of the output shaft of the driving motor (605) is fixedly connected to a lifting screw (606). When working, the driving motor (601) can drive the central axis rotating cylinder (603) to rotate.

2. The nano-crushing and grinding device for biological preparations according to claim 1, characterized in that: The grinding assembly (7) is composed of a ball nut pair moving seat (701), a fixed annular block (702), a supporting protective sleeve (703), a lifting drive frame (704), a rotating connecting rod (705), a grinding ball (706), a fixed extension block (707), a spring (708), a striking head (709) and a guide slide rod (710); The ball nut pair moving seat (701) is threadedly connected to the outside of the lifting screw (606), the fixed annular block (702) is fixedly connected to the top of the ball nut pair moving seat (701), the support protection sleeve (703) is fixedly connected to the outside of the fixed annular block (702), the lifting drive frame (704) is fixedly connected to the outside of the support protection sleeve (703), the rotating connecting rod (705) is rotatably connected to the middle part of the lifting drive frame (704), and the grinding ball (706) is rotatably connected to the rotating connecting rod (705). The connecting rod (705) is away from one end of the lifting drive frame (704), the fixed extension block (707) is fixedly connected to one end of the grinding ball (706) away from the rotating connecting rod (705), the spring 1 (708) is fixedly connected to the outside of the fixed extension block (707), the striking head 1 (709) is fixedly connected to the other end of the spring 1 (708), the guide slide bar (710) is fixedly connected to the outside of the fixed extension block (707), and the grinding ball (706) can rotate outside the rotating connecting rod (705).

3. The nano-crushing and grinding device for biological preparations according to claim 2, characterized in that: It also includes a knocking assembly (8), which is composed of an elliptical disc (801), a positioning plate (802), a second spring (803), a force plate (804), an air storage cylinder (805), a piston moving frame (806), a knocking base (807), a knocking box (808), a third spring (809), a piston plate (810), a second knocking head (811) and an air connecting pipe (812); The elliptical disc (801) is fixedly connected to the outer side of the output shaft of the driving motor (601); the positioning plate (802) is fixedly connected to the top of the fixed circular plate (5); the second spring (803) is fixedly connected to the side of the positioning plate (802) close to the elliptical disc (801); the force plate (804) is fixedly connected to the end of the second spring (803) away from the positioning plate (802); the air storage cylinder (805) is fixedly connected to the side of the positioning plate (802) away from the elliptical disc (801); the piston moving frame (806) is fixedly connected to the middle of the side of the force plate (804) away from the driving motor (601); The striking base (807) is fixedly connected to the outer side of the top of the fixed circular plate (5), the striking box (808) is fixedly connected to the top of the striking base (807), the spring three (809) is fixedly connected to the inner bottom of the striking box (808), the piston plate (810) is fixedly connected to the top of the spring three (809), the striking head two (811) is fixedly connected to the top of the piston plate (810), and the air connecting pipe (812) is fixedly connected to the middle part of the outer side of the air storage cylinder (805). The elliptical disc (801) rotates with the driving motor (601), so that the elliptical disc (801) can press the force-bearing plate (804).

4. The nano-crushing and grinding device for biological preparations according to claim 3, characterized in that: The output shaft of the driving motor (601) passes through the middle of the fixed circular plate (5) and extends to the top of the fixed circular plate (5) to be fixedly connected to the bottom of the central axis rotating cylinder (603); a fixed disc is fixedly connected inside the lifting screw (606); the bottom of the lifting screw (606) is rotatably connected to the top of the fixed disc, so as to support the lifting screw (606).

5. The nano-crushing and grinding device for biological preparations according to claim 4, characterized in that: The outer side of the central axis rotating cylinder (603) is provided with a lifting groove for accommodating the lifting of the ball nut pair moving seat (701); the inner bottom of the ball nut pair moving seat (701) is provided with a guide groove; the ball nut pair moving seat (701) is slidably connected to the outer wall of the central axis rotating cylinder (603) via the guide groove, so that the ball nut pair moving seat (701) can be lifted and lowered on the outer side of the central axis rotating cylinder (603).

6. The nano-crushing and grinding device for biological preparations according to claim 5, characterized in that: A guide circular groove is provided in the striking head (709), and the striking head (709) is slidably connected to the outer wall of the guide slide bar (710) through the guide circular groove. A limiting disc is provided at one end of the guide slide bar (710) away from the fixed extension block (707), so that the striking head (709) can be guided and moved outside the guide slide bar (710).

7. The nano-crushing and grinding device for biological preparations according to claim 6, characterized in that: The end of the air connecting pipe (812) away from the air storage cylinder (805) is fixedly connected to the outer bottom of the knocking box (808); the interior of the air storage cylinder (805) is connected to the inner bottom of the knocking box (808) through the air connecting pipe (812); the piston moving frame (806) is slidably connected to the inner wall of the air storage cylinder (805); the piston plate (810) is slidably connected to the inner wall of the knocking box (808); the top end of the second knocking head (811) passes through the top of the knocking box (808) and extends to the top of the knocking box (808); the second knocking head (811) can knock on the bottom of the screening basket (602).

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