Dynamic blood vessel phantom suitable for digital subtraction angiography technology and working method

By designing a dynamic vascular phantom including a piezoelectric pump and a replaceable phantom module, the problem that the prior art cannot simulate the dynamic changes of vascular vessels in the human body is solved, accurate simulation of vasoconstriction and diastolic and simulation of different tissue characteristics is achieved, and the imaging control quality of digital subtraction angiography technology is improved.

CN120036814APending Publication Date: 2025-05-27SHANDONG FIRST MEDICAL UNIV & SHANDONG ACADEMY OF MEDICAL SCI +1
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Patent Information

Application Number
CN202510306583.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-14
Publication Date
2025-05-27

AI Technical Summary

Technical Problem

The existing digital subtraction angiography phantoms cannot simulate the dynamic changes of human blood vessels, and cannot accurately simulate the tissue structure around the blood vessels, resulting in the imaging results that cannot accurately fit the actual vascular imaging in the tissue.

Method used

A dynamic vascular phantom is designed, including a piezoelectric pump and a replaceable phantom module, which applies a continuous triangular waveform voltage through the piezoelectric pump, causing liquid in the phantom module to be pumped and retention, simulating the contraction and dilation of blood vessels, and simulating the vascular characteristics of different organs and tissues by replacing different modules.

Benefits of technology

It accurately simulates the contraction and dilation of human blood vessels in vitro, can simulate the vascular characteristics of different organs and tissues, and improves the imaging control quality of digital subtraction angiography technology.

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Abstract

The invention relates to a dynamic blood vessel phantom suitable for a digital subtraction angiography technology and a working method, and belongs to the field of medical imaging system quality control. The phantom comprises a piezoelectric pump, a replaceable phantom module and a pump cover. The replaceable phantom is connected with the stand column on the right side of the piezoelectric pump through the hole in the left side. The pump cover is connected with an opening in the upper portion of the piezoelectric pump through a stand column below the pump cover; the replaceable phantom is connected with the hole in the right side of the pump cover through the stand column on the left side. The driving method comprises the steps that the piezoelectric vibrator in the piezoelectric pump periodically vibrates under the action of continuous triangular waveform voltage, the volume of a pump cavity is periodically changed, then pressure difference is periodically generated on the two sides of the one-way valve, and liquid is pumped in and pumped out under the action of the pressure difference. The dynamic process of expansion and contraction of a real blood vessel in a normal physiological state can be simulated, and the method has a good application prospect in the field of quality control of a digital subtraction angiography technology.
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Description

Technical Field

[0001] The present invention relates to the field of quality control of medical imaging systems, and in particular to a dynamic vascular phantom and a working method suitable for digital subtraction angiography technology, which can be used in the field of imaging control of digital subtraction angiography technology. Background Art

[0002] Digital subtraction angiography is a medical imaging technology widely used in cardiovascular angiography. Its imaging principle is: inject contrast agent into human blood vessels, use x-rays to irradiate and image the designated parts, input two images taken before and after the injection of contrast agent into the computer, remove the bone tissue and soft tissue images through subtraction, enhancement and re-imaging, and obtain clear images of the blood vessel cavity; the existing digital subtraction angiography phantoms are divided into plug-in type and remote control type. Both digital subtraction angiography phantoms choose to carve strip grooves on the surface of the phantom to simulate blood vessels, but are limited by the choice of phantom materials and the simulation method of blood vessels. No matter which phantom is used, it can only simulate human blood vessels in a static state, and cannot simulate the dynamic changes of blood vessels themselves under normal physiological conditions of the human body. Therefore, after imaging, it is impossible to obtain an image that is more in line with the actual situation of the human body; in addition, according to the function, the existing digital subtraction angiography phantoms are all performance testing phantoms, which can only simulate the basic morphological characteristics and imaging characteristics of blood vessels, and do not fully simulate the structural characteristics of blood vessels themselves and the tissues around blood vessels, resulting in that the simulation results cannot accurately fit the actual vascular imaging situation in the tissue. In summary, it is crucial to design a digital subtraction angiography phantom that can simulate blood vessels in different real human tissue environments in vitro. Summary of the invention

[0003] The purpose of the present invention is to provide a dynamic vascular phantom suitable for digital subtraction angiography technology, solve the above-mentioned problems existing in the prior art, achieve miniaturization and diversification, and simulate the contraction and relaxation of human blood vessels under physiological conditions.

[0004] The technical solution adopted by the present invention to achieve the above-mentioned purpose is as follows.

[0005] A dynamic vascular phantom suitable for digital subtraction angiography technology, characterized in that it comprises a piezoelectric pump 1, a replaceable phantom module 2, and a pump cover 3; the piezoelectric pump 1 comprises a pump body 1-1, a piezoelectric vibrator 1-2, a one-way valve cover 1-3, a one-way valve sheet 1-4, and a water tank 1-5; the replaceable phantom module 2 comprises a module housing 2-1, a soft tissue phantom bottom 2-2, a soft tissue phantom top 2-3, a vascular phantom 2-4, a prestressed valve bottom 2-5, a prestressed valve sheet 2-6, a prestressed valve top 2-7, and a bone tissue phantom cover 2-8; the replaceable The phantom 2 is connected to the column on the right side of the piezoelectric pump 1 via the opening on the left side; the pump cover 3 is connected to the opening on the top of the piezoelectric pump 1 via the column below; the replaceable phantom 2 is connected to the opening on the right side of the pump cover 3 via the column on the left side; the soft tissue phantom bottom 2-2 is connected to the soft tissue phantom top 2-3 up and down via a slot, and the blood vessel phantom 2-4 is placed in the hole between the two; the prestressed valve bottom 2-5 is connected to the prestressed valve top 2-7 and the module housing 2-1 via a slot; the bone tissue phantom cover 2-8 and the pump cover 3 are connected to each other via a slot.

[0006] The present invention also provides a working method capable of realizing a dynamic vascular phantom applicable to digital subtraction angiography technology, comprising the following steps: (a) A continuous triangular waveform voltage is applied to the piezoelectric vibrator 1-2 of the piezoelectric pump 1, and the piezoelectric vibrator 1-2 vibrates up and down periodically, so that the volume of the pump chamber changes periodically, resulting in a periodic pressure difference between the upper and lower surfaces of the inlet and outlet one-way valve plate 1-4. The pressure difference guides the inlet and outlet one-way valve plate 1-4 to open periodically and pump the liquid from the water tank 1-5 into the replaceable body phantom module 2; the prestressed valve plate 2-6 closes the prestressed valve port by virtue of its own elasticity. Due to the presence of the prestressed valve plate 2-6, the liquid entering the replaceable body membrane module 2 from the piezoelectric pump 1 is retained in the replaceable body membrane module 2 and continuously accumulates, causing the blood vessel phantom 2-4 to expand toward the surroundings, thereby simulating the expansion of the blood vessel; when the pressure difference on both sides of the prestressed valve plate 2-6 exceeds the maximum value of its own elastic force, the liquid will flow out until the pressure difference on both sides of the prestressed valve plate 2-6 is less than the maximum value of its own elastic force, and the blood vessel phantom 2-4 contracts, thereby simulating the contraction of the blood vessel; (b) By replacing different soft tissue phantom bottoms 2-2, soft tissue phantom tops 2-3, blood vessel phantoms 2-4 and bone tissue phantom covers 2-8, the blood vessel characteristics of different organs, different tissues and different physiological and pathological conditions can be simulated.

[0007] The beneficial effects of the present invention are: simple structure, easy processing and assembly, able to accurately simulate the contraction and relaxation of human blood vessels in vitro, helpful to assist in the improvement and enhancement of digital subtraction angiography systems, and having good application prospects in the field of digital subtraction angiography technology quality control. BRIEF DESCRIPTION OF THE DRAWINGS

[0008] The drawings described herein are used to provide further understanding of the present invention and constitute a part of this application. The illustrative examples of the present invention and their descriptions are used to explain the present invention and do not constitute improper limitations on the present invention.

[0009] Figure 1 It is an exploded view of the overall three-dimensional structure of the present invention.

[0010] Figure 2 It is a three-dimensional structure explosion diagram of the piezoelectric pump of the present invention.

[0011] Figure 3 It is an exploded cross-sectional view of the three-dimensional structure of the piezoelectric pump of the present invention.

[0012] Figure 4 It is an exploded view of the three-dimensional structure of the replaceable phantom module of the present invention.

[0013] Figure 5 It is an exploded cross-sectional view of the three-dimensional structure of the replaceable phantom module of the present invention.

[0014] Figure 6 It is a driving voltage timing diagram of the present invention.

[0015] In the figure: 1. piezoelectric pump; 1-1. pump body; 1-2. piezoelectric vibrator; 1-3. one-way valve cover; 1-4. one-way valve plate; 2. replaceable phantom module; 2-1. module housing; 2-2. soft tissue phantom bottom; 2-3. soft tissue phantom top; 2-4. blood vessel phantom; 2-5. prestressed valve bottom; 2-6. prestressed valve plate; 2-7. prestressed valve top; 2-8. bone tissue phantom cover; 3. pump cover. Specific implementation methods

[0016] The details and specific implementation modes of the present invention are further described below with reference to the accompanying drawings.

[0017] See also Figures 1 to 3As shown, the dynamic vascular phantom for digital subtraction angiography technology of the present invention is characterized by comprising a piezoelectric pump 1, a replaceable phantom module 2, and a pump cover 3; the piezoelectric pump 1 comprises a pump body 1-1, a piezoelectric vibrator 1-2, a one-way valve cover 1-3, a one-way valve sheet 1-4, and a water tank 1-5; the replaceable phantom module 2 comprises a module housing 2-1, a soft tissue phantom bottom 2-2, a soft tissue phantom top 2-3, a vascular phantom 2-4, a prestressed valve bottom 2-5, a prestressed valve sheet 2-6, a prestressed valve top 2-7, and a bone tissue phantom cover 2-8 ... The replaceable phantom 2 is connected to the column on the right side of the piezoelectric pump 1 via the opening on the left side; the pump cover 3 is connected to the opening on the top of the piezoelectric pump 1 via the column below; the replaceable phantom 2 is connected to the opening on the right side of the pump cover 3 via the column on the left side; the soft tissue phantom bottom 2-2 is connected to the soft tissue phantom top 2-3 up and down via a slot, and the blood vessel phantom 2-4 is placed in the hole between the two; the prestressed valve bottom 2-5 is connected to the prestressed valve top 2-7 and the module housing 2-1 via a slot; the bone tissue phantom cover 2-8 and the pump cover 3 are connected to each other via a slot.

[0018] See also Figures 1 to 6 As shown, a working method of a dynamic vascular phantom applicable to digital subtraction angiography technology is specifically described, including: (a) A continuous triangular waveform voltage is applied to the piezoelectric vibrator 1-2 of the piezoelectric pump 1, and the piezoelectric vibrator 1-2 vibrates up and down periodically, so that the volume of the pump chamber changes periodically, resulting in a periodic pressure difference between the upper and lower surfaces of the inlet and outlet one-way valve plate 1-4. The pressure difference guides the inlet and outlet one-way valve plate 1-4 to open periodically and pump the liquid from the water tank 1-5 into the replaceable body phantom module 2; the prestressed valve plate 2-6 closes the prestressed valve port by virtue of its own elasticity. Due to the presence of the prestressed valve plate 2-6, the liquid entering the replaceable body membrane module 2 from the piezoelectric pump 1 is retained in the replaceable body membrane module 2 and continuously accumulates, causing the blood vessel phantom 2-4 to expand toward the surroundings, thereby simulating the expansion of the blood vessel; when the pressure difference on both sides of the prestressed valve plate 2-6 exceeds the maximum value of its own elastic force, the liquid will flow out until the pressure difference on both sides of the prestressed valve plate 2-6 is less than the maximum value of its own elastic force, and the blood vessel phantom 2-4 contracts, thereby simulating the contraction of the blood vessel; (b) By replacing different soft tissue phantom bottoms 2-2, soft tissue phantom tops 2-3, blood vessel phantoms 2-4, and bone tissue phantom covers 2-8, the vascular characteristics of different organs, different tissues, and different physiological and pathological states can be simulated.

[0019] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. of the present invention shall be included in the protection scope of the present invention.

Claims

1. A dynamic vascular phantom suitable for digital subtraction angiography, characterized in that: The invention comprises a piezoelectric pump 1, a replaceable phantom module 2, and a pump cover 3; the piezoelectric pump 1 comprises a pump body 1-1, a piezoelectric vibrator 1-2, a one-way valve cover 1-3, a one-way valve sheet 1-4, and a water tank 1-5; the replaceable phantom module 2 comprises: a module housing 2-1, a soft tissue phantom bottom 2-2, a soft tissue phantom top 2-3, a blood vessel phantom 2-4, a prestressed valve bottom 2-5, a prestressed valve sheet 2-6, a prestressed valve top 2-7, and a bone tissue phantom cover 2-8; the replaceable phantom 2 is connected to the piezoelectric pump by means of an opening on the left side. 1; the pump cover 3 is connected to the opening above the piezoelectric pump 1 through the column below; the replaceable phantom 2 is connected to the opening on the right side of the pump cover 3 through the column on the left; the soft tissue phantom bottom 2-2 is connected to the soft tissue phantom top 2-3 up and down through the slot, and the blood vessel phantom 2-4 is placed in the hole between the two; the prestressed valve bottom 2-5 is connected to the prestressed valve top 2-7 and the module housing 2-1 through the slot; the bone tissue phantom cover 2-8 and the pump cover 3 are connected to each other through the slot.

2. The working method of a dynamic vascular phantom suitable for digital subtraction angiography technology according to claim 1, characterized in that: (a) A continuous triangular waveform voltage is applied to the piezoelectric vibrator 1-2 of the piezoelectric pump 1, and the piezoelectric vibrator 1-2 vibrates up and down periodically, so that the volume of the pump chamber changes periodically, resulting in a periodic pressure difference between the upper and lower surfaces of the inlet and outlet one-way valve plate 1-4. The pressure difference guides the inlet and outlet one-way valve plate 1-4 to open periodically and pump the liquid from the water tank 1-5 into the replaceable body phantom module 2; the prestressed valve plate 2-6 closes the prestressed valve port by virtue of its own elasticity. Due to the presence of the prestressed valve plate 2-6, the liquid entering the replaceable body membrane module 2 from the piezoelectric pump 1 is retained in the replaceable body membrane module 2 and continuously accumulates, causing the blood vessel phantom 2-4 to expand toward the surrounding, thereby simulating the expansion of the blood vessel; when the pressure difference on both sides of the prestressed valve plate 2-6 exceeds the maximum value of its own elastic force, the liquid will flow out until the pressure difference on both sides of the prestressed valve plate 2-6 is less than the maximum value of its own elastic force, and the liquid flows back to the water tank 1-5, and the blood vessel phantom 2-4 contracts accordingly, thereby simulating the contraction of the blood vessel; (b) By replacing different soft tissue phantom bottoms 2-2, soft tissue phantom tops 2-3, blood vessel phantoms 2-4 and bone tissue phantom covers 2-8, the blood vessel characteristics of different organs, different tissues and different physiological and pathological conditions can be simulated.