Composition containing ceramide and application of composition in preparation of products for improving scalp health

Abstract

The invention relates to the field of daily chemicals, in particular to a ceramide-containing composition and application thereof in preparation of products for improving scalp health. The composition provided by the invention comprises ceramide and a plant extract, after optimization, the composition has a remarkable synergistic effect, and the effect of improving scalp health can be achieved by improving the filagaridin level and / or improving the scalp moisture content.

Description

Technical Field

[0001] The present invention relates to the daily chemical field, and particularly to the application of a ceramide-containing composition and its preparation in products for improving scalp health. Background Art

[0002] Under the influence of the fast-paced life and environmental changes, scalp health problems occur frequently and have attracted much attention. As the foundation of hair, scalp health is related to the appearance and overall health of hair. At present, there are many common scalp problems. Dandruff problems are common, with a large amount of scales shedding and accompanied by itching; seborrheic dermatitis is manifested as scalp erythema, greasy desquamation, and when severe, erosion, exudation and intolerable itching; hair loss problems also trouble many people, such as androgenetic alopecia, alopecia areata, etc., affecting the image and bringing psychological pressure.

[0003] The causes of scalp problems are relatively complex and may be caused by factors such as excessive sebum secretion, bacterial or fungal infections, scalp dryness, chemical damage, lack of nutrition, allergies, etc. These factors will cause problems such as increased dandruff, scalp itching, scalp inflammation, hair loss, etc. Once the barrier function of the scalp is damaged, the scalp will be more vulnerable to external stimuli and the water loss will accelerate, thus aggravating scalp problems.

[0004] Facing these problems, people have an urgent need for scalp repair. One is to regulate scalp sebum secretion, restore the water-oil balance, and solve problems from the root; the second is to inhibit the overgrowth of microorganisms, reduce inflammation, and relieve related symptoms; the third is to promote blood circulation in the hair follicles, provide nutrition, and stimulate hair growth. In addition, due to factors such as perming and dyeing, the scalp barrier is damaged, and the ability of the scalp to resist external stimuli decreases. Therefore, it is crucial to restore the scalp barrier function. An ideal scalp care product should be able to promote the repair and regeneration of scalp cutinocytes, enhance the scalp barrier function, and let the scalp restore its healthy self-protection ability. At the same time, the product needs to have good safety and mildness to avoid secondary damage. However, existing scalp care products mostly target single problems and are difficult to fully meet the needs. Therefore, it is of great practical significance to develop a maintenance composition that comprehensively solves various scalp problems.

[0005] Ceramide is one of the main components that make up the skin barrier and is a natural moisturizing factor in the skin. 40%-50% of the sebum in the human stratum corneum is composed of ceramide, which also occupies an important position in the intercellular matrix, plays a key role in the balance of stratum corneum moisture, has a strong ability to bind water molecules, and can enhance the skin's moisturizing function. With the continuous development of the cosmetics industry and the increasing maturity of formulation technology, if ceramide can be reasonably combined with other effective ingredients to make a stable and effective scalp repair product, it will bring better effects to scalp repair. Summary of the Invention

[0006] In view of this, the technical problem to be solved by the present invention is to provide the application of a ceramide-containing composition in the preparation of a product for improving scalp health.

[0007] The composition provided by the present invention comprises ceramide and plant extract.

[0008] In the present invention, the ceramide is composed of ceramide NP, ceramide AS and ceramide NS / ceramide NG; the mass ratio of ceramide NP, ceramide AS and ceramide NS / ceramide NG is (0.05-0.2):(0.05-0.2):(0.05-0.2).

[0009] In some embodiments, the mass ratio of the acylneuraminate NP, ceramide AS and ceramide NS / ceramide NG is (0.05 to 0.1):(0.05 to 0.1):(0.05 to 0.1), or (0.05 to 0.1):(0.05 to 0.2):(0.1 to 0.2), or (0.05 to 0.1):(0.05 to 0.3):(0.05 to 0.2), or (0.05 to 0.1):(0.1 to 0.2):(0.05 to 0.1), or (0.05 to 0.1):(0.1 to 0.3):(0.1 to 0.2), or (0.05 to 0.1):(0.1 to 0.4):(0.05 to 0.2), or (0.05 to 0.1):(0.05 to 0.2):(0.05 to 0.1), or (0.05 to 0.1):(0.05 to 0.2):(0.1 to 0.2), or (0.05 to 0.1):(0.05 to 0.2):(0.05 to 0.2), or (0.1 to 0.2):(0.05 to 0.1):(0.05 to 0.1), or (0.1 to 0.2):(0.05 to 0.2):(0.1 to 0.2), or (0.1 to 0.2):(0.05 to 0.3):(0.05 to 0.2), or (0.1 to 0.2):(0.1 to 0.2):(0.05 to 0.1), or (0.1 to 0.2):(0.1 to 0.3):(0.1 to 0.2), or (0.1 to 0.2):(0.1 to 0.4):(0.05 to 0.2), or (0.1 to 0.2):(0.05 to 0.2):(0.05 to 0.1), or (0.1 to 0.2):(0.05 to 0.2):(0.1 to 0.2), or (0.1 to 0.2):(0.05 to 0.2):(0.05 to 0.2), or (0.05 to 0.2):(0.05 to 0.1):(0.05 to 0.1), or (0.05 to 0.2):(0.05 to 0.2):(0.1 to 0.2), or (0.05 to 0.2):(0.05 to 0.3):(0.05 to 0.2), or (0.05 to 0.2):(0.1 to 0.2):(0.05 to 0.1), or (0.05 to 0.2):(0.1 to 0.3):(0.1 to 0.2), or (0.05 to 0.2):(0.1 to 0.4):(0.05 to 0.2), or (0.05 to 0.2):(0.05 to 0.2):(0.05 to 0.1), or (0.05 to 0.2):(0.05 to 0.2):(0.1 to 0.2), or (0.05 to 0.2):(0.05 to 0.2):(0.05 to 0.2).

[0010] In specific embodiments, the mass ratio of the ceramide NP, ceramide AS, and ceramide NS / ceramide NG is 0.1:0.1:0.1, or 0.05:0.05:0.2, or 0.05:0.2:0.05, or 0.2:0.05:0.05.

[0011] In the present invention, ceramides with specific compositions and ratios are used in combination with plant extracts, and it is found that they can produce a better effect on improving scalp health. The plant extracts can be selected from ginger extract, polygonum multiflorum extract, ginseng extract, biota orientalis extract, rosemary extract, tea seed extract, aloe extract, angelica extract, black sesame extract, or olive leaf extract. However, through the Bliss independent model and the King's method calculation, when the plant extracts include at least one of sapindus mukorossi fruit extract, curcuma longa root extract, and polygonum multiflorum root extract, a synergistic effect can be achieved.

[0012] In some embodiments, the plant extracts are composed of sapindus mukorossi fruit extract, curcuma longa root extract, and polygonum multiflorum root extract, and the mass ratio of the sapindus mukorossi fruit extract, curcuma longa root extract, and polygonum multiflorum root extract is (1-5):(1-5):(1-5). As a feasible case, the mass ratio of the sapindus mukorossi fruit extract, curcuma longa root extract, and polygonum multiflorum root extract is 5:5:5.

[0013] In the present invention, ceramides and plant extracts produce a synergistic effect at a specific ratio. In some embodiments, the mass ratio of the ceramide to the plant extract is (0.1-0.5):(10-20). In specific embodiments, the mass ratio of the ceramide to the plant extract is 0.3:15.

[0014] In the present invention, the composition exists in a powder state or can also exist in a solution state, and the present invention does not limit this. When in a solution state, the working concentrations of the components in the composition are: ceramide NP 0.05 wt% - 0.2 wt%, ceramide AS 0.05 wt% - 0.2 wt%, ceramide NS / ceramide NG 0.05 wt% - 0.2 wt%, sapindus mukorossi fruit extract 1 wt% - 5 wt%, curcuma longa root extract 1 wt% - 5 wt%, and polygonum multiflorum root extract 1 wt% - 5 wt%, and the balance is water or an acceptable solvent. When the composition is in a solution state, the components exist at the working concentration or at 2-100 times the working concentration. For example, 2-fold concentration, 5-fold concentration, 10-fold concentration, 20-fold concentration, 25-fold concentration, 50-fold concentration, or 100-fold concentration.

[0015] Furthermore, the present invention also provides the application of the described composition in the preparation of products for improving scalp health.

[0016] In the present invention, the improvement of scalp health includes increasing the level of filaggrin and / or increasing the water content of the scalp.

[0017] The present invention also provides a product for improving scalp health, which comprises the composition as described above and a matrix component.

[0018] In some embodiments, the matrix component includes a polyol, an emulsifier, a thickener, a preservative, and an oily raw material.

[0019] Specifically:

[0020] The polyol includes at least one of glycerol, 1,3-propanediol, butanediol, and 1,2-hexanediol.

[0021] The emulsifier includes at least one of hydrogenated lecithin, M82, and polyglyceryl-10 stearate.

[0022] The thickener includes polyacrylate cross-linked polymer-6.

[0023] The preservative includes phenoxyethanol.

[0024] The oily raw material includes at least one of Limnanthes Alba (Meadowfoam) Seed Oil, caprylic / capric triglyceride, tocopheryl acetate, and octyldodecanol.

[0025] In some embodiments, the product for improving scalp health includes 15.3 wt% of the composition as described above, 10 wt% of polyol, 3 wt% of emulsifier, 0.4 wt% of thickener, 0.6 wt% of preservative, 5 wt% of oily raw material, and the balance is water.

[0026] More specifically, the product includes the following components in mass fractions:

[0027]

[0028] Furthermore, the present invention also provides a preparation method of the product as described above, which includes:

[0029] Mix water, glycerol, 1,3-propanediol, butanediol, 1,2-hexanediol, and polyacrylate cross-linked polymer-6, and dissolve at 80 - 90 °C to obtain an aqueous phase;

[0030] Mix ceramide NP, ceramide AS, ceramide NS / ceramide NG, caprylic / capric triglyceride, Limnanthes Alba (Meadowfoam) Seed Oil, tocopheryl acetate, and octyldodecanol, and dissolve at 80 - 90 °C, then add hydrogenated lecithin, M82, and polyglyceryl-10 stearate, and stir and dissolve at 80 - 90 °C to obtain an oil phase;

[0031] The oil phase is added to the water phase. After emulsification and dispersion, the temperature is lowered to 35-45°C, and sapindus mukorossi fruit extract, curcuma longa root extract, polygonum multiflorum root extract and phenoxyethanol are added to obtain the product.

[0032] In the present invention, the product is an external product, and its types include but are not limited to shampoo, hair conditioner, hair mask, scalp essence, scalp spray, cream, gel, lotion, jelly, hair oil, leave-in hair conditioner, scalp massage cream, scalp scrub, scalp styling gel, liquid hair wax, hot oil treatment, root volumizing spray, anti-hair loss and hair growth promoting liquid, scalp soothing gel, foam hair conditioner, hair mousse, etc.

[0033] Furthermore, the present invention also provides a method for improving scalp health, which includes applying the composition as described above or applying the product as described above, or applying the product prepared by the preparation method as described above on the scalp surface of a subject.

[0034] In the present invention, the application methods include but are not limited to smearing, massaging, rinsing, spraying, dropping, applying, rubbing, brushing, spraying, leave-in wiping, etc.

[0035] The composition provided by the present invention includes ceramide and plant extracts. After optimization, the composition has a significant synergistic effect and can improve scalp health by increasing the level of filaggrin and / or increasing the scalp moisture content. Description of the Drawings

[0036] Figure 1 Show the water increase rate of the scalp repair cream. Detailed Embodiments

[0037] The present invention provides an application of a ceramide-containing composition and its preparation in improving scalp health products. Those skilled in the art can draw on the content of this article and appropriately improve the process parameters to achieve it. It should be particularly noted that all similar substitutions and modifications are obvious to those skilled in the art, and they are all regarded as included in the present invention. The methods and applications of the present invention have been described through preferred embodiments, and those related can obviously make changes or appropriate alterations and combinations to the methods and applications in this article without departing from the content, spirit and scope of the present invention to implement and apply the technology of the present invention.

[0038] The test materials used in the present invention are all ordinary commercially available products and can be purchased in the market.

[0039] In the present invention, the ceramide NP is a mixture composed of ceramide III: ceramide IIIA: ceramide IIIB = 2:5:3. The preparation processes of ceramide III, ceramide IIIA, and ceramide IIIB are as follows: Add phytosphingosine and 5 - 10 times the volume (weight ratio) of methanol into a reactor, add 0.1 - 1.5 equivalents of sodium methoxide, stir evenly, add 1.1 - 1.5 equivalents of fatty acid ester (preferably methyl ester), heat the system to 50 - 60 °C, and react for 8 - 16 hours until the phytosphingosine reaction is complete. Cool the system to 0 - 5 °C, slowly add acetic acid to quench the reaction, add 5 - 10 times the volume (weight ratio) of water, concentrate under reduced pressure to remove methanol, extract twice with 5 - 10 times the volume of ethyl acetate (weight ratio), dry the organic layer over anhydrous sodium sulfate, concentrate under reduced pressure to an oily state, add 3 - 5 times the volume of petroleum ether, stir at 0 - 5 °C for 3 - 5 hours, and allow the solid to precipitate fully. Filter and collect the solid, and dry to obtain the product ceramide NP.

[0040] Among them:

[0041] ① The structural formula of ceramide III is:

[0042]

[0043] ② The structural formula of ceramide IIIA is:

[0044]

[0045] ③ The structural formula of ceramide IIIB is:

[0046]

[0047] Ceramide AS (0.1% - 0.5 wt%) is sourced from Evonik Specialty Chemicals (Shanghai) Co., Ltd.

[0048] The extracts of Sapindus mukorossi fruit, Curcuma longa root, and Polygonum multiflorum root are sourced from Guangzhou Baoyi Biotechnology Co., Ltd. The remaining excipients are common commercially available raw materials, sourced from Guangzhou Baihaobo Co., Ltd.

[0049] The ceramide NP, ceramide NS / ceramide NG of the present invention are from Shenzhen Realand Biotechnology Co., Ltd.

[0050] The present invention will be further illustrated below in conjunction with the examples:

[0051] Preparation of the scalp repair lotion in Examples 1 - 6

[0052] The formulations of each example are shown in Table 1:

[0053] Table 1 Formulations of Each Example

[0054]

[0055] Note: M82 is a mixture of 65% cetearyl alcohol and 35% cocoglucoside. The preparation method includes:

[0056] (1) Mix water, glycerin, 1,3-propanediol, butanediol, 1,2-hexanediol, and polyacrylate crosspolymer-6, and then heat up to 85 °C, stirring to dissolve and disperse.

[0057] (2) Mix ceramide NP, ceramide AS, ceramide NS / ceramide NG, caprylic / capric triglyceride, limnanthes alba seed oil, tocopheryl acetate, and octyldodecanol, and then heat up to 85 °C, stirring until the solvent is completely dissolved.

[0058] (3) Keep the temperature at 85 °C, and then add hydrogenated lecithin, M82, and polyglyceryl-10 stearate to step (2), stirring to dissolve and disperse well.

[0059] (4) Pour step (3) into step (1), after emulsifying and dispersing well, prepare to cool down.

[0060] (5) Cool down to 40 °C, add sapindus mukorossi fruit extract, curcuma longa root extract, polygonum multiflorum root extract, and phenoxyethanol, and stir evenly.

[0061] Efficacy verification:

[0062] Verify several scalp repair lotions prepared in Example 1, and compare the repair effects on the scalp and hair.

[0063] I. Repair efficacy test

[0064] (1) Experimental principle:

[0065] Filaggrin (FLG) is a key component in the assembly process of CE (cornified envelope of epidermal keratinocytes). In addition to being a structural component of the skin and scalp barrier, FLG can also be hydrolyzed by Caspase-14 (cysteine protease) to form natural moisturizing factors. Therefore, the repair efficacy of the test sample can be evaluated by observing the change in the content of model filaggrin (FLG) after administration.

[0066] (2) Experimental method

[0067] This test uses sodium lauryl sulfate (SLS) to stimulate a 3D epidermal skin model Construct an in vitro skin injury model, and evaluate the repair efficacy of the test sample by detecting the change in the content of filaggrin (FLG) in the skin model after the action of the sample.

[0068] (3) Experimental reagents

[0069] EpiGrowth culture medium (a culture medium containing various amino acids, vitamins, minerals, etc.)

[0070] PBS (phosphate buffered saline)

[0071] 0.2% SLS (sodium lauryl sulfate)

[0072] Positive control group: 50 μM WY14643 ((C 14 H 13 CIN 4 OS)

[0073] FLG antibody (mouse monoclonal FLG antibody, immunofluorescence staining reagent)

[0074] 4% paraformaldehyde

[0075] (4) Experimental equipment

[0076] CO 2 Incubator, laminar flow hood, upright microscope, fluorescence microscope

[0077] (5) Experimental calculation

[0078] Bliss independence model and King's method: Using the incidence rate of the drug action object as the efficacy index, the quantitative value range of the efficacy is 0 to 1. Taking drug A and drug B as examples, regarding the drug effects of drug A and drug B as independent events, borrowing the probability formula P AB = P A + P B - P A * P B , using this formula as the calculation formula for the expected additive effect of combined drug application E AB = E A + E B - E A * E B . Taking the ratio of the actual efficacy value to the value calculated by this formula as CI, and the calculation formula is as shown in formula (V).

[0079]

[0080] CI > 1 is synergistic, CI = 1 is additive, and CI < 1 is antagonistic.

[0081] (6) Experimental method

[0082] ① Preparation of working solution

[0083] 1) Preparation of 0.1% SLS working solution: Pipette 1 mL of 0.2% SLS solution and add 1 mL of PBS to prepare 0.1% SLS working solution.

[0084] 2) Preparation of the working solution for the positive control group (50 μM WY14643): Add 10 μL of the WY14643 mother solution (30 mM) to 6 mL of the model culture medium to prepare a 50 μM working solution.

[0085] ② Administration to the 3D epidermal skin model

[0086] 1) Transfer the 3D epidermal skin model to two 6-well plates (2.5 mL well plates) (previously added with 0.9 mL of EpiGrowth culture medium), and label the test group numbers on the 6-well plates. Randomly divide the cells into a sample group, a positive control group, a negative control group, and a blank control group. Among them: the sample is the composition of Examples 1 to 6.

[0087] 2) Treatments for each group include:

[0088] Blank (1): Add the sample of Blank (1) in Table 1 on the surface and dilute it with pure water to a concentration of 2% (v / v).

[0089] Sample group: Add 12.5 μL of 0.2% SLS solution and 12.5 μL of the sample working solution at the corresponding concentration on the surface.

[0090] Positive control group (PC): Add 12.5 μL of 50 μM WY14643 and 12.5 μL of 0.2% SLS solution.

[0091] Negative control group (NC): Treat the 3D epidermal skin model with 12.5 μL of 0.1% SLS.

[0092] Blank (2) control group (BC): Only perform fluorescence staining on the 3D epidermal skin model.

[0093] Distribute each group on the surface of the model and place it in a CO 2 incubator (37 °C, 5% CO 2 ) and incubate for 24 h.

[0094] 3) After incubation, wash the residual test substances on the surface of the 3D epidermal skin model with sterile PBS solution, and wipe off the residual liquid inside and outside the model with a sterile cotton swab.

[0095] 4) Take the 3D epidermal skin model for detection, fix it with 4% paraformaldehyde at 20 - 25 °C, and after 24 h of fixation, perform immunofluorescence detection of filaggrin (FLG), take pictures and observe under a microscope, collect pictures and analyze.

[0096] 5) Repeat the above experimental steps 3 times.

[0097] 6) Experimental data (Table 2) and experimental summary

[0098] Table 2

[0099]

[0100] According to the IOD value of FLG in (Table 2), it can be seen that the PC effect of the positive control group is the best, followed by Example 2. The arrangement order of each group of samples is: PC > Example 2 > Example 6 > Example 3 > Example 4 > Example 5 > Example 1 > Blank (1).

[0101] Explanation ①: Compared with the BC group, the FLG content in the NC group decreased significantly, indicating that the stimulation conditions of this test are effective.

[0102] Explanation ②: The effect of the composition of 0.1% Ceramide NP, 0.1% Ceramide AS, and 0.1% Ceramide NS / Ceramide NG on the production of FLG in this example formula is better than that of 3% Panthenol.

[0103] Explanation ③: The effect of the composition of 0.1% Ceramide NP, 0.1% Ceramide AS, and 0.1% Ceramide NS / Ceramide NG on the production of FLG is better than that of (0.05% Ceramide NP, 0.05% Ceramide AS, 0.2% Ceramide NS / Ceramide NG composition), better than (0.2% Ceramide NP, 0.05% Ceramide AS, 0.05% Ceramide NS / Ceramide NG composition), and also better than (0.05% Ceramide NP, 0.2% Ceramide AS, 0.05% Ceramide NS / Ceramide NG composition).

[0104] Explanation ④: The effect of the composition examples containing 0.05 - 0.2% Ceramide NP, 0.05 - 0.2% Ceramide AS, and 0.05 - 0.2% Ceramide NS / Ceramide NG on the production of FLG is better than those without addition.

[0105] II. Scalp Moisturizing Function Test

[0106] (1) Experimental Background and Principle:

[0107] The nutrition of hair comes from the scalp. Just like the skin, it needs sufficient water content to be plump and moist. When the scalp is moisturized, the hair strands will naturally be shiny and lustrous.

[0108] Influence of Moisture on Maintaining Scalp Health:

[0109] ① Maintaining the skin barrier function: In a dry environment, if the scalp loses too much moisture, the cutin layer will become dry and fragile, and its barrier function will weaken. Just like a wall with cracks, harmful substances are more likely to penetrate, which may cause problems such as scalp itching and redness.

[0110] ②Regulate the microbial balance: An appropriate amount of moisture creates a relatively stable scalp ecological environment, which helps the growth of beneficial microorganisms. If the scalp is too dry, the balance of the microbial community may be disrupted, and harmful microorganisms may take the opportunity to multiply in large numbers, leading to scalp diseases. Of course, if the scalp is too wet, it may also cause abnormal proliferation of microorganisms (such as fungi), resulting in increased dandruff, seborrheic dermatitis, etc.

[0111] ③Promote cell metabolism: Water is an important medium for various chemical reactions in the process of cell metabolism. When the scalp lacks water, cell metabolism will be affected, and situations such as slow cell renewal and accumulation of the stratum corneum will occur, resulting in a rough scalp.

[0112] (2) Experimental methods

[0113] ①Six healthy, non-allergic, and bald volunteers aged 18 - 60 years were selected for the experiment in an environment with a room temperature of 16 - 28°C and a humidity of 40% - 60%. Before the experiment, the volunteers needed to be quiet in this environment for at least 30 minutes. After the environment reached equilibrium, 9 experimental areas of 1 cm × 1 cm were drawn on the head of each volunteer with a non-toxic marker pen, and the interval between the areas was at least 1 - 2 cm.

[0114] The self-made scalp repair lotion formulated with a complex of multiple ceramides and plant extracts was applied to the test sites at a dose of (2.0 ± 0.1) mg / cm2. After the subjects used the scalp repair lotion for 0 min, 30 min, 2 h, and 4 h, the technical staff used the probe of the skin moisture tester to measure the moisture content of the experimental sites, and the average value of 3 measurements was taken as the test value.

[0115] Moisture increase rate = (Moisture content after use - Moisture content before use) / Moisture content before use × 100%

[0116] ②The moisture increase rates of the scalp repair lotion formulated with a complex of multiple ceramides and plant extracts are shown in Table 3:

[0117]

[0118] The moisture increase rates of the scalp repair lotion formulated with a complex of multiple ceramides and plant extracts are as Figure 1 .

[0119] The results show that the order of the moisture growth rates of each example is: Example 2 > Example 6 > Example 4 > Example 3 > Example 5 > Example 1 > Blank (1) group. In this experimental case, the combined moisturizing effect of the combination of 0.1% ceramide NP, 0.1% ceramide AS, and 0.1% ceramide NS / ceramide NG composition is better than that of other combinations.

[0120] The above are only the preferred embodiments of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and modifications can be made, and these improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. A composition comprising ceramide and a plant extract; The ceramide is composed of ceramide NP, ceramide AS and ceramide NS / ceramide NG; the mass ratio of ceramide NP, ceramide AS and ceramide NS / ceramide NG is (0.05-0.2):(0.05-0.2):(0.05-0.2); The plant extract comprises at least one of a soapberry fruit extract, a turmeric root extract and a polygonum multiflorum root extract.

2. The composition according to claim 1, characterized in that The mass ratio of ceramide NP, ceramide AS and ceramide NS / ceramide NG is 0.1:0.1:0.

1.

3. The composition according to claim 1, characterized in that The plant extract consists of soapberry fruit extract, turmeric root extract and polygonum multiflorum root extract, wherein the mass ratio of the soapberry fruit extract, the turmeric root extract and the polygonum multiflorum root extract is 5:5:

5.

4. The composition according to any one of claims 1 to 3, characterized in that The mass ratio of the ceramide to the plant extract is 0.3:

15.

5. Use of the composition according to any one of claims 1 to 4 in the preparation of a product for improving scalp health.

6. A product for improving scalp health, comprising the composition according to any one of claims 1 to 5 and a base component.

7. The product according to claim 6, characterized in that The invention comprises 15.3 wt% of the composition according to any one of claims 1 to 5, 10 wt% of polyol, 3 wt% of emulsifier, 0.4 wt% of thickener, 0.6 wt% of preservative, 5 wt% of oily raw material, and the balance is water.

8. The product according to claim 6, characterized in that The components include the following mass fractions: The balance is water.

9. A method for preparing the product according to claim 8, comprising: Mix water, glycerin, 1,3-propylene glycol, butylene glycol, 1,2-hexanediol, and polyacrylate cross-linked polymer-6, and dissolve them at 80-90° C. to obtain an aqueous phase; Ceramide NP, ceramide AS, ceramide NS / ceramide NG, caprylic / capric triglyceride, meadowfoam seed oil, tocopheryl acetate, and octyldodecanol were mixed and dissolved at 80-90° C., and then hydrogenated lecithin, M82, and polyglyceryl-10 stearate were added and stirred and dissolved at 80-90° C. to obtain an oil phase; The oil phase is added into the water phase, and after emulsification and dispersion, the temperature is lowered to 35-45° C., and soapberry fruit extract, turmeric root extract, Polygonum multiflorum root extract and phenoxyethanol are added to obtain the product.

10. A method for improving scalp health, comprising applying the composition of any one of claims 1 to 4 or the product of any one of claims 6 to 8, or the product prepared by the preparation method of claim 9 to the scalp surface of a subject.

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