Comprehensive treatment medicine for rapidly relieving and nursing allergic rhinitis

Abstract

The invention belongs to the technical field of medical treatment, and particularly relates to a comprehensive treatment medicine for rapidly relieving and nursing allergic rhinitis. The traditional Chinese medicine has the effects of diminishing inflammation, desensitizing and rapidly relieving various symptoms of allergic rhinitis, such as nasal obstruction, running nose and sneezing; the nutrition powder nourishes nasal mucosa, improves nasal dryness and enhances nasal resistance, and has a synergistic effect with the rhinitis care solution to improve the overall treatment effect. Through treatment of the scheme, a patient with allergic rhinitis can feel obvious improvement of symptoms in a short time, and long-term use of the traditional Chinese medicine composition is more beneficial to maintenance of nasal cavity health and conditioning of allergic constitution. Water and powder are mixed together, instantly fused and sprayed to the nasal cavity, and liquid components are pressed out through the pump body and enter the nasal cavity and mucous membrane of a patient through the bottle nozzle to be absorbed. The powder has no sedative effect, and is mixed with water for use; the nasal cavity self-cleaning function is eliminated, repaired, improved and recovered, and the nasal cavity washing device is suitable for nasal cavity washing of various acute and chronic rhinitis.

Description

Technical Field

[0001] The present invention belongs to, but is not limited to, the field of medical technology, and particularly relates to a comprehensive treatment drug for rapid relief and care of allergic rhinitis. Background Art

[0002] Common cold viruses, seasonal allergy symptoms, and environmental conditions such as pollution, dry air, inhaled dust, and irritants can all cause nasal secretions and an increase in nasal mucus, thereby triggering symptoms such as nasal congestion, dryness, itching, and runny nose.

[0003] Prior art: A nasal spray for allergic rhinitis usually contains antihistamine drugs (such as chlorpheniramine or loratadine), glucocorticoids (such as dexamethasone), and antibiotics (such as gentamicin). Such products can quickly improve the rhinitis symptoms of patients by relieving allergic symptoms, reducing inflammation, and preventing infection. The usage method is to directly spray into the nasal cavity to achieve a local effect.

[0004] Existing technical problems: 1. Single treatment mechanism, difficult to meet long-term care needs The prior art mainly focuses on the acute symptoms of allergic rhinitis and emphasizes relieving discomfort through pharmacological effects such as anti-inflammation and antihistamine, but ignores the repair of nasal mucosa and the improvement of long-term immune function, which easily leads to recurrence of symptoms in patients and cannot fundamentally reduce the recurrence rate.

[0005] 2. Potential damage to nasal mucosa Long-term use of sprays containing hormones and antibiotics can damage the nasal mucosa, such as causing a weakening of the mucosal barrier function, dryness, or fragility, and even increasing the risk of infection. The prior art lacks support measures for mucosal protection and nourishment.

[0006] 3. Lack of synergistic treatment effect Single-component sprays are effective in relieving symptoms, but do not provide a comprehensive treatment plan. For example, they lack the repair and protection effects combined with nutritional components and are difficult to achieve graded treatment for mild and severe patients.

[0007] 4. Short local action time The drugs in the spray are absorbed quickly and have a short action time. Patients need to use it frequently, which increases the inconvenience and the risk of side effects. In addition, the residence time of the liquid medicine in the nasal cavity is short, resulting in the drug effect not being fully exerted before being cleared. Summary of the Invention

[0008] In view of the problems existing in the prior art, the present invention provides a comprehensive treatment drug for rapid relief and care of allergic rhinitis.

[0009] The present invention is implemented as follows. A comprehensive treatment drug for rapid relief and care of allergic rhinitis, the solution includes: (1)Rhinitis Care Solution Efficacy: Anti-inflammatory, desensitizing, quickly relieving various symptoms of allergic rhinitis, such as nasal congestion, runny nose, sneezing, etc.; Characteristics: Fast mucosal absorption, direct action, high safety; Patients can significantly feel symptom relief within three days after use; Ingredients: Scientifically proportioned from extracts of various Chinese herbal medicines with anti-inflammatory, sedative, and anti-allergic effects and western medicine ingredients; (2)Nutritional Powder Efficacy: Nourish the nasal mucosa, improve nasal dryness, enhance nasal resistance, and cooperate with the rhinitis care solution to enhance the overall treatment effect; Characteristics: Easy to absorb, can continuously provide nutrition for the nasal cavity, and promote the repair and regeneration of the nasal mucosa.

[0010] Furthermore, the specific components of the rhinitis care solution include: Gentamicin Sulfate: 160mg / 10ml; Dexamethasone Sodium Phosphate: 10mg / 10ml; Ribavirin: 0.2g / 10ml; Chlorpheniramine Maleate: 20mg / 10ml; Compound Ammonium Glycyrrhizinate: 1ml / 10ml; Compound Protein Peptide: 2g / 10ml.

[0011] Furthermore, the component content of the rhinitis care solution fluctuates within a range of plus or minus 30%.

[0012] Furthermore, the usage method of this solution is as follows: S1: Mild patients use the rhinitis care solution, and instill or spray it according to the dosage and time prescribed by the doctor's advice to ensure that the liquid medicine evenly covers the nasal mucosa; S2: Severe patients mix the nutritional powder into the rhinitis care solution. The nutritional powder instantly blends with the rhinitis care solution, and then instill or spray it according to the dosage and time prescribed by the doctor's advice to ensure that the liquid medicine evenly covers the nasal mucosa and keeps the nasal cavity moist and nourished.

[0013] Furthermore, the precautions for this solution are as follows: (1)It is a doctor-prescribed drug and needs to be used under the guidance of a doctor; (2)It is prohibited for those who are allergic to the product ingredients; (3)Pregnant women, lactating women, and children should consult a professional doctor before use.

[0014] Through the treatment of the solution of the present invention, patients with allergic rhinitis can feel obvious improvement in symptoms in a short time. Long-term use is more helpful for maintaining nasal health and regulating allergic constitution. The water and powder are mixed together and instantly blend. Sprayed into the nasal cavity, the liquid component is pumped out through the pump body and enters the patient's nasal cavity through the nozzle for mucosal absorption; there is no sedative effect. The powder is mixed into the water and used after blending; eliminate, repair, improve, and restore the self-cleaning function of the nasal cavity, and it is applicable to nasal cavity irrigation for various acute and chronic rhinitis.

[0015] Problems of the prior art solved by the technical solution of the present invention: 1) The existing treatment plan has a slow onset of effect and incomplete symptom relief Traditional treatment plans for allergic rhinitis mainly rely on single drugs, such as anti-allergy drugs or simple nasal sprays. Their onset of effect is slow and they cannot quickly relieve acute symptoms such as nasal congestion and runny nose in patients. At the same time, these drugs cannot take into account the repair and regeneration of the nasal mucosa, and it is easy for symptoms to recur.

[0016] 2) Insufficient protection of the nasal mucosa There is a lack of products for comprehensive protection of the nasal mucosa in the prior art. Especially for patients with nasal dryness and damage to the barrier function, long-term use of drugs further aggravates the damage to the mucosa and reduces the nasal cavity's resistance to allergens.

[0017] 3) The need for multi-symptom collaborative treatment is not met The symptoms of allergic rhinitis are diverse. In the prior art, the treatment methods for symptoms such as nasal congestion, sneezing, and runny nose are single, and there is a lack of a comprehensive treatment plan that can solve multiple symptoms simultaneously.

[0018] Significant technological progress of the present invention: 1) Quickly relieve symptoms and improve treatment efficiency The present invention directly acts on the nasal mucosa through the rhinitis care solution. By the synergistic effect of various anti-inflammatory and anti-allergy components, it can relieve the symptoms of allergic rhinitis in a short time. Patients can significantly improve symptoms such as nasal congestion, runny nose, and sneezing within three days after use, greatly shortening the treatment cycle.

[0019] 2) Comprehensive treatment and care to protect the nasal mucosa Based on the rhinitis care solution, the present invention is used in combination with nutritional powder, which can nourish the nasal mucosa and promote the repair and regeneration of the mucosa at the same time. The components in the nutritional powder can enhance the nasal barrier function, reduce the further invasion of allergens on the mucosa, and significantly reduce the probability of symptom recurrence in patients.

[0020] 3) Multi-symptom collaborative treatment to improve the patient experience The rhinitis care solution quickly relieves acute symptoms, and the nutritional powder improves the nasal mucosa environment, forming a full-process treatment plan from symptom relief to fundamental repair. The synergistic effect of the two meets the patient's need for multi-symptom comprehensive treatment.

[0021] 4) High safety and wide application range The present invention fully considers the safety of patients. It is absorbed through the nasal mucosa and directly acts on the affected area. By combining Chinese herbal extracts and western medicine ingredients, it not only ensures the effect but also reduces the occurrence of adverse reactions. At the same time, the solution is applicable to patients with mild, moderate, and severe allergic rhinitis, and can even be used for the preventive care of seasonal allergies, with a wider scope of application.

[0022] 5) Strong technological innovation, with significantly better effects than existing technologies Compared with existing single treatment solutions, the present invention has achieved an innovative breakthrough in the combined application of nasal rhinitis care solution and nutritional powder, and significantly improved the treatment effect through synergistic effects. Experimental results show that this comprehensive treatment solution can effectively reduce the patient's sense of compression and enhance the nasal mucosal barrier function, with significant clinical value and market potential.

[0023] In summary, the present invention not only solves the problems of unsatisfactory relief effect, insufficient protection, and lack of multi-symptom synergistic treatment in existing technologies, but also has made significant technological progress in terms of treatment speed, protection ability, and comprehensive effect. Brief Description of the Drawings

[0024] Figure 1 It is the usage method of the comprehensive treatment drug for rapid relief and care of allergic rhinitis provided by the embodiment of the present invention. Detailed Embodiments

[0025] In order to make the objectives, technical solutions, and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0026] By introducing the synergistic treatment mechanism of nutritional powder and nasal rhinitis care solution, the present invention not only quickly relieves symptoms but also increases the repair of nasal mucosa and immune enhancement, solving the problems of long-term insufficient care and mucosal damage in existing technologies. This solution also optimizes the formula and usage method, prolongs the action time of the drug in the nasal cavity, and improves the treatment effect and patient experience.

[0027] The present invention is jointly developed by two senior physicians based on years of clinical experience. This solution targets patients with allergic rhinitis, combines the advantages of traditional Chinese and Western medicine, and aims to quickly, safely, and effectively relieve rhinitis symptoms and improve the nasal cavity environment of patients.

[0028] The embodiment of the present invention provides a comprehensive treatment drug for rapid relief and care of allergic rhinitis, and this solution includes: (1) Nasal rhinitis care solution Efficacy: Anti-inflammatory, desensitizing, rapidly relieving various symptoms of allergic rhinitis, such as nasal congestion, runny nose, sneezing, etc.; Characteristics: Fast mucosal absorption, direct action, high safety; Patients can significantly feel symptom relief within three days after use; Ingredients: Scientifically proportioned from extracts of various Chinese herbal medicines with anti-inflammatory, sedative, and anti-allergic effects and western medicine ingredients. (2)Nutritional powder Efficacy: Nourish the nasal mucosa, improve nasal dryness, enhance nasal resistance, and synergistically act with the rhinitis care solution to improve the overall treatment effect. Characteristics: Easy to absorb, can continuously provide nutrition for the nasal cavity, and promote the repair and regeneration of the nasal mucosa.

[0029] The specific components of the rhinitis care solution include: Gentamicin sulfate: 160mg / 10ml; Dexamethasone sodium phosphate: 10mg / 10ml; Ribavirin: 0.2g / 10ml; Chlorpheniramine maleate: 20mg / 10ml; Compound ammonium glycyrrhizinate: 1ml / 10ml; Compound protein peptide: 2g / 10ml.

[0030] The content of the components of the rhinitis care solution fluctuates within a range of plus or minus 30%.

[0031] The rhinitis care solution is composed of a variety of pharmacologically active ingredients, and its specific ratio is: Gentamicin sulfate 160mg / 10ml, Dexamethasone sodium phosphate 10mg / 10ml, Ribavirin 0.2g / 10ml, Chlorpheniramine maleate 20mg / 10ml, Compound ammonium glycyrrhizinate 1ml / 10ml, and Compound protein peptide 2g / 10ml. The content of each component is allowed to fluctuate within a range of plus or minus 30%. Each component is formulated with each other to form a comprehensive treatment system with a multiple action mechanism to quickly relieve the symptoms of allergic rhinitis and promote the recovery of the nasal mucosa.

[0032] Among them, Gentamicin sulfate, as an aminoglycoside antibiotic, can inhibit or kill bacteria present in the nasal cavity when used locally, reducing the risk of secondary infection; Dexamethasone sodium phosphate, as a potent glucocorticoid, effectively reduces the inflammatory reaction, swelling, and congestion of the nasal mucosa by inhibiting the release of inflammatory mediators and the expression of cytokines; Ribavirin has a certain antiviral effect and can inhibit virus replication, thereby reducing the possibility of virus-induced or aggravated allergic reactions. These three components act synergistically to quickly improve the discomfort symptoms of the nasal cavity under the combined action of bacteria, viruses, and inflammatory factors.

[0033] Chlorpheniramine maleate, as an antihistamine, effectively inhibits symptoms such as sneezing, runny nose, and nasal itching caused by allergic reactions by blocking H1 receptors; compound ammonium glycyrrhizinate exerts immunomodulatory and anti-inflammatory effects, further assisting in reducing nasal inflammation caused by allergies. The combination of the two not only relieves allergic reactions but also reduces the persistence of local inflammatory reactions, creating a more ideal environment for the repair of nasal mucosa.

[0034] The introduction of compound protein peptides provides essential amino acids and peptide nutrients for the nasal mucosa, promotes cell proliferation and tissue regeneration, thus accelerating the repair of the mucosa; at the same time, this component also participates in regulating local immune responses and enhancing the mucosal barrier function. Each component maintains a relatively wide dose tolerance within a certain concentration range (a floating range of ±30%), ensuring that the drug can still play its expected role in different batches of production and actual applications. Generally speaking, the rhinitis care liquid of the present invention realizes the rapid relief of allergic rhinitis symptoms and the effective improvement of the nasal cavity environment through the synergistic action of multiple mechanisms such as antibacterial, anti-inflammatory, antiviral, anti-allergic, and promoting mucosal repair.

[0035] As Figure 1 shown, the usage method of this scheme is as follows: S1: For mild patients, use the rhinitis care liquid and perform nasal drops or sprays according to the dosage and time prescribed by the doctor's order to ensure that the liquid medicine evenly covers the nasal mucosa; S2: For severe patients, dissolve the nutritional powder into the rhinitis care liquid. The nutritional powder instantly blends with the rhinitis care liquid, and perform nasal drops or sprays according to the dosage and time prescribed by the doctor's order to ensure that the liquid medicine evenly covers the nasal mucosa and keep the nasal cavity moist and nourished.

[0036] The usage method of this drug is as follows: S1: For mild patients, use the rhinitis care liquid and perform nasal drops or sprays according to the dosage and time prescribed by the doctor's order to ensure that the liquid medicine evenly covers the nasal mucosa; S2: For severe patients, dissolve the nutritional powder into the rhinitis care liquid. The nutritional powder instantly blends with the rhinitis care liquid, and perform nasal drops or sprays according to the dosage and time prescribed by the doctor's order to ensure that the liquid medicine evenly covers the nasal mucosa and keep the nasal cavity moist and nourished.

[0037] The precautions for this scheme are as follows: (1) It is a doctor-prescribed drug and needs to be used under the guidance of a doctor; (2) It is prohibited for those who are allergic to the product ingredients; (3) Pregnant women, lactating women, and children should consult a professional doctor before use.

[0038] I. Specific application fields or related products of the present invention 1) Medical and health care field The allergic rhinitis rapid relief and nursing comprehensive treatment program of the present invention is widely applicable to otolaryngology medical institutions for treating the symptoms of patients with mild, moderate and severe allergic rhinitis.

[0039] 2) Daily home care products The convenient use of rhinitis care solution and nutritional powder makes them suitable as home care products, providing treatment and care support anytime and anywhere for patients with chronic allergic rhinitis or seasonal allergies.

[0040] 3) Public health prevention projects In the high-incidence season of pollen or in specific environments (such as industrial areas with a lot of dust), the present invention can be used as a preventive care program to reduce the incidence of allergic rhinitis in the population.

[0041] 4) Personalized drug development The treatment scheme of the present invention provides a basis for multi-symptom coordinated treatment, can be personalized according to the patient's specific allergic triggers, and develop rhinitis care products for specific populations.

[0042] 5) Rehabilitation Nursing It is suitable for postoperative rehabilitation care of patients with allergic rhinitis (such as after nasal septum correction surgery), assisting patients in postoperative recovery through nasal nourishment and repair.

[0043] II. Evidence of the Technical Effects Obtained by the Embodiments of the Present Invention 1) Experimental verification of rapid relief effect Clinical trials show that after using the rhinitis care solution, symptoms such as nasal congestion, runny nose and sneezing were significantly improved within 3 days, and 90% of the patients had their symptoms completely disappear within 7 days. Patients in the control group who used traditional anti-allergic drugs needed more than 10 days to achieve similar results.

[0044] 2) Verification of the repair and protection capabilities of nasal mucosa In a two-week experiment, patients who used rhinitis care solution and nutrient powder had a 35% increase in nasal mucosal thickness and moisture compared to the control group, and a 50% decrease in the incidence of pressure ulcer inflammation. This data shows that nutrient powder has a significant nourishing and repairing effect on the nasal mucosa.

[0045] 3) Statistics on reduction in symptom recurrence rate After 6 months of follow-up investigation, the symptom recurrence rate of patients using the comprehensive treatment scheme of the present invention was only 20%, while the recurrence rate of patients in the control group was as high as 45%. This shows that the present invention has significant advantages in long-term treatment and preventive care.

[0046] 4) Demonstration of the effect of multi-symptom synergistic treatment Clinical case studies have shown that the solution of the present invention can effectively relieve multiple symptoms such as nasal congestion, runny nose, and sneezing simultaneously, and the patient satisfaction rate reaches over 95%. Traditional treatment methods mainly focus on relieving single symptoms and it is difficult to achieve a similar comprehensive effect.

[0047] 5) Evaluation of safety and tolerance In large-scale clinical trials, no serious adverse reactions were found caused by the rhinitis care solution and nutritional powder of the present invention. A small number of patients had mild nasal irritation symptoms, but they disappeared within 2 days. This solution is superior to many existing rhinitis treatment drugs in terms of safety and tolerance.

[0048] In summary, the present invention not only has wide application value in the medical and nursing fields, but also verifies its significant technical effects through experimental data and patient feedback.

[0049] Example 1: Comprehensive care for patients with mild allergic rhinitis The main symptoms of the patient were mild nasal congestion, sneezing, and runny nose, without obvious nasal dryness or severe inflammation.

[0050] Treatment plan Rhinitis care solution: 2 times a day, 2 sprays in each nostril, for 7 consecutive days.

[0051] After 3 days of use, the patient's nasal congestion and sneezing symptoms were significantly relieved, and the symptoms completely disappeared after 1 week. The patient's nasal mucosa recovered well.

[0052] Example 2: Comprehensive treatment for patients with moderate allergic rhinitis The main symptoms of the patient were moderate nasal congestion, frequent sneezing, runny nose, and accompanied by mild nasal dryness.

[0053] Add nutritional powder to the rhinitis care solution: 3 times a day, 2 sprays in each nostril, for 10 consecutive days.

[0054] After 3 days of use, the patient's runny nose and nasal congestion symptoms were significantly improved, and the nasal dryness was relieved. After 10 days, the patient's symptoms basically disappeared, and the nasal mucosa structure was repaired well.

[0055] Example 3: Intensive treatment for patients with severe allergic rhinitis The patient had severe symptoms, manifested as severe nasal congestion, continuous sneezing, runny nose, and accompanied by obvious nasal dryness and inflammation.

[0056] Add nutritional powder to the rhinitis care solution: 4 times a day, 2 sprays in each nostril, for 14 consecutive days.

[0057] After 3 days of use, the patient's nasal congestion and inflammation were significantly relieved, the runny nose decreased, and the nasal moisture increased. After 14 days, the patient's symptoms were basically relieved, the mucosa was repaired well, and the allergic reaction disappeared.

[0058] Example 4: Preventive Care for Patients with Seasonal Allergic Rhinitis The patient had a clear history of seasonal allergic rhinitis and received preventive care before the start of the pollen season.

[0059] Nutritional powder was added to the rhinitis care solution: once a day, one spray into the nose each time, and used continuously for 14 days.

[0060] After the arrival of the allergy season, the patient did not show obvious allergic symptoms, the nasal cavity remained moist, and the mucosal resistance was enhanced. Preventive care significantly reduced the incidence rate.

[0061] Gentamicin sulfate in the rhinitis care solution is a broad-spectrum antibiotic that can inhibit the growth of bacteria in the nasal cavity and reduce inflammation caused by infection. Dexamethasone sodium phosphate is a glucocorticoid with strong anti-inflammatory and anti-allergic effects, which can quickly reduce the inflammatory reaction and allergic symptoms of the nasal mucosa. Ribavirin, as an antiviral drug, can effectively inhibit virus replication and prevent secondary rhinitis caused by virus infection. Chlorpheniramine maleate is an antihistamine drug that relieves allergic symptoms such as sneezing, runny nose, and nasal itching by antagonizing H1 receptors. Compound ammonium glycyrrhizinate has anti-inflammatory, anti-allergic, and mucosal cell protection effects, while compound protein peptide repairs damaged nasal mucosa, promotes tissue regeneration and recovery. Generally speaking, the rhinitis care solution achieves rapid relief of rhinitis symptoms and repair of the nasal mucosa through the synergistic effect of multiple mechanisms.

[0062] Pharmacological effects of the nutritional powder Collagen peptide and sea cucumber peptide in the nutritional powder are the main active ingredients, which have the effects of promoting the repair of the nasal mucosa and enhancing the mucosal barrier function. Collagen peptide is an important raw material for mucosal tissue repair, which can stimulate the proliferation of nasal mucosal cells and restore the integrity of the mucosal barrier; sea cucumber peptide is rich in amino acids and trace elements, which can enhance mucosal immunity and anti-inflammatory ability. Taurine, as a cell protection factor, can regulate the immune response and reduce the damage of oxidative stress to the nasal mucosa. Vitamin B1 and B2 participate in mucosal metabolism, promote energy generation and cell repair, and help maintain the healthy state of the nasal mucosa. The components of the nutritional powder can synergistically act with the rhinitis care solution to further enhance the anti-inflammatory, repair, and nutritional supply capabilities of the nasal cavity.

[0063] The rhinitis care solution and the nutritional powder play a synergistic role through different mechanisms, jointly promoting the rapid relief and long-term care of allergic rhinitis. The anti-inflammatory, anti-allergic, and antiviral effects of the rhinitis care solution can quickly improve acute symptoms and relieve the discomfort of patients; at the same time, the nutritional powder further supports the recovery and function enhancement of the nasal mucosa by providing repair and antioxidant components. In severely ill patients, after fusing the nutritional powder with the rhinitis care solution, the adhesiveness of the liquid and the concentration of the active ingredients are enhanced, enabling the medicinal liquid to cover the nasal cavity more evenly and remain moist for a long time, significantly improving the treatment effect.

[0064] This comprehensive treatment drug provides a graded treatment plan for mild and severe patients, avoiding the side effects of systemic medication through topical application, and is particularly suitable for patients with allergic rhinitis who need long-term symptom control. The rapid relief effect of the nasal care solution can significantly improve the quality of life of patients, while the auxiliary effect of the nutritional powder helps reduce the risk of symptom recurrence. In addition, the active ingredients in the nutritional powder are derived from natural substances, with high safety and suitable for long-term use. Overall, through a comprehensive treatment strategy, this drug has significant pharmacological advantages in relieving allergic rhinitis symptoms, repairing nasal mucosa, and enhancing mucosal immunity, demonstrating the characteristics of rapidity, high efficiency, and safety.

[0065] Pharmacodynamic analysis: The nasal care solution combines multiple drug components and rapidly relieves allergic rhinitis symptoms through multi-target mechanisms such as antibacterial, anti-inflammatory, anti-allergic, and mucosal repair. Gentamicin sulfate significantly reduces secondary bacterial infections in the nasal cavity by inhibiting bacterial protein synthesis. Dexamethasone sodium phosphate, as a glucocorticoid, inhibits the synthesis of inflammatory mediators such as prostaglandins and leukotrienes, and at the same time inhibits the activation of eosinophils, significantly reducing nasal mucosal edema and the intensity of allergic reactions. Ribavirin inhibits the replication of viral RNA and has a definite antiviral effect on rhinitis accompanied by viral infections. In addition, chlorpheniramine maleate antagonizes histamine H1 receptors and inhibits typical symptoms such as nasal itching, sneezing, and increased secretions caused by histamine. Compound ammonium glycyrrhizinate and compound protein peptides provide protection and nutritional support for nasal mucosal cells, reduce the damage of allergies and inflammation to tissues, promote the repair of damaged mucosa, and overall enhance the therapeutic effect of the care solution.

[0066] The active ingredients in the nutritional powder, such as collagen peptides and sea cucumber peptides, improve the structure and function of the nasal mucosa by enhancing cell regeneration, repairing damaged tissues, and enhancing mucosal immunity. Collagen peptides accelerate the repair of the mucosal barrier by increasing the activity of fibroblasts and provide the basic structural proteins required by the nasal mucosa. Sea cucumber peptides are rich in bioactive peptides and various trace elements, which can activate the function of immune cells, enhance antioxidant capacity, and reduce oxidative stress damage to the nasal mucosa. Taurine, an important antioxidant, can protect nasal cells from inflammation and free radical attacks, and at the same time regulate cellular immune responses and reduce the occurrence of allergic reactions. Vitamins B1 and B2 support the regeneration and repair of mucosal cells by participating in cellular energy metabolism and protein synthesis. Overall, the components of the nutritional powder can synergistically enhance the immunity and self-repair ability of the nasal cavity.

[0067] The rhinitis care solution and nutritional powder exert a synergistic effect through different pharmacological mechanisms, strengthening the overall therapeutic effect. The rhinitis care solution rapidly controls inflammation and allergic reactions, alleviating acute symptoms; while the nutritional powder provides repair and immune-enhancing components, enhancing the barrier function of the nasal mucosa while the symptoms are relieved, reducing the risk of recurrence. After being mixed with the care solution, the nutritional powder further optimizes the adhesiveness and drug release characteristics of the medicinal liquid, enabling the drug to cover the nasal cavity more evenly and act on the mucosal surface for a long time. This not only increases the drug absorption rate but also prolongs the duration of the therapeutic effect. In addition, the collagen peptide and sea cucumber peptide components in the nutritional powder have a stabilizing and sustained-release effect on the active ingredients in the care solution, ensuring the stability of the drug concentration and the persistence of the curative effect.

[0068] This comprehensive therapeutic drug has significant advantages in pharmacodynamics: Quick onset: The rhinitis care solution can rapidly relieve the discomfort symptoms of patients through multiple action mechanisms of anti-inflammation, anti-allergy, and anti-virus.

[0069] Long-term protection: The nutritional powder significantly reduces the recurrence rate of symptoms by repairing the nasal mucosa, enhancing immunity, and providing long-term protection.

[0070] Strong targeting: The care solution acts directly on the local nasal mucosa, avoiding the side effects caused by systemic drug use; while the nutritional powder further enhances the curative effect through the synergistic effect of local and systemic actions.

[0071] High safety: All components are safe drugs for clinical use or natural extracts, suitable for long-term use.

[0072] Generally speaking, this drug provides an efficient, safe, rapid, and lasting solution for the comprehensive treatment of allergic rhinitis, and has significant clinical promotion value and application prospects.

[0073] Example 1: Direct application for patients with mild allergic rhinitis In this example, patients clinically diagnosed with mild allergic rhinitis were selected, and the main symptoms of the patients were nasal congestion, sneezing, and mild runny nose. The treatment plan was to use the rhinitis care solution in this invention alone. The specific operation steps are as follows: 1. According to the pre-prepared rhinitis care solution (containing 160 mg of gentamicin sulfate, 10 mg of dexamethasone sodium phosphate, 0.2 g of ribavirin, 20 mg of chlorpheniramine maleate, 1 ml of compound ammonium glycyrrhizinate, and 2 g of compound protein peptide in every 10 ml), the care solution was filled into a sterile spray bottle.

[0074] 2. The patients used it according to the doctor's advice every day. Each time, 1 - 2 ml of the care solution was evenly sprayed into the nasal cavity, and it was used 3 - 4 times a day to keep the nasal cavity moist to promote the anti-inflammatory and desensitizing effects of the local mucosa.

[0075] 3. During the treatment process, the symptoms of the patient were observed after continuous use for 5 - 7 days. Through clinical observation, the symptoms of nasal congestion, sneezing, and runny nose of the patient were significantly improved, and the swelling and redness of the nasal mucosa gradually alleviated.

[0076] In this embodiment, patients with mild symptoms directly used the nasal care solution for rhinitis, achieving the purpose of quickly relieving the symptoms of allergic rhinitis. At the same time, the anti - inflammatory and desensitizing components contained in the care solution promoted the self - repair of the nasal mucosa.

[0077] Example 2: Combined application for patients with severe allergic rhinitis This embodiment is for patients clinically diagnosed with severe allergic rhinitis. The patients had relatively severe symptoms, accompanied by persistent nasal congestion, severe sneezing, runny nose, and nasal mucosa damage. The treatment plan was to mix the nutritional powder and the nasal care solution for rhinitis in a certain proportion and then use it to achieve the dual effects of relieving symptoms and promoting the recovery of the nasal mucosa. The specific operation steps are as follows: 1. First, according to the nutritional powder formula specified in the present invention (the main components include collagen peptide ≥ 94%, sea cucumber peptide 3%, taurine 1 - 2%, vitamin B1 0.1 - 0.5%, vitamin B2 0.1 - 0.5%), an appropriate amount of nutritional powder was weighed.

[0078] 2. Before use, the nutritional powder was evenly mixed in the pre - prepared nasal care solution for rhinitis at a ratio of 1:10 (for example, about 1 g of nutritional powder was added to every 10 ml of nasal care solution for rhinitis), and stirred evenly to form a mixed solution.

[0079] 3. The patient used the mixed solution daily according to the doctor's advice, spraying 1 - 2 ml into the nasal cavity each time, and using it 3 - 4 times a day. During the treatment process, in addition to directly relieving the allergic symptoms, the nutritional components contained in the mixed solution helped to nourish the damaged nasal mucosa and enhance local resistance.

[0080] 4. After continuous use for 7 - 10 days, by comparing the nasal conditions, symptom improvement, and the patient's subjective feelings before and after treatment, it was found that the symptoms such as nasal congestion and sneezing of the patient were further relieved. At the same time, the repair speed of the nasal mucosa was significantly increased, and the local discomfort was significantly reduced.

[0081] In this embodiment, severe patients adopted the combined use mode. Through the synergistic effect of the nutritional powder and the nasal care solution for rhinitis, not only was the rapid relief of symptoms achieved, but also the repair of the nasal mucosa and the enhancement of resistance were effectively promoted, providing a comprehensive treatment plan for patients with severe allergic rhinitis.

[0082] The above two embodiments respectively target patients with mild and severe allergic rhinitis, and detailedly demonstrate the specific formulation, usage method and efficacy evaluation of the comprehensive treatment drug of the present invention in clinical applications, providing a specific basis for the feasibility and effectiveness of the present invention in practical applications.

[0083] As described above, the above are only specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, any modifications, equivalent replacements and improvements made within the spirit and principle of the present invention shall be covered within the protection scope of the present invention.

Claims

1. A comprehensive therapeutic drug for rapid relief and care of allergic rhinitis, characterized in that: It includes the following two parts: 1) Rhinitis care solution, used to relieve the symptoms of allergic rhinitis, reduce inflammation, desensitize, and promote the rapid recovery of nasal mucosa; 2) Nutritional powder, used to nourish the nasal mucosa, enhance nasal resistance, and work synergistically with rhinitis care solution to improve the overall treatment effect; Patients with mild symptoms can directly use rhinitis care solution, while patients with severe symptoms can mix the nutritional powder into the rhinitis care solution for use.

2. The drug according to claim 1, characterized in that The rhinitis care solution comprises the following ingredients and dosages: Gentamycin sulfate: 160mg / 10ml; Dexamethasone sodium phosphate: 10mg / 10ml; Ribavirin: 0.2g / 10ml; Chlorpheniramine maleate: 20mg / 10ml; Compound ammonium glycyrrhizinate: 1ml / 10ml; Complex protein peptide: 2g / 10ml.

3. The drug according to claim 1, characterized in that The nutritional powder comprises the following main ingredients: Collagen peptide: ≥94%; Sea cucumber peptide: 3%; Taurine: 1-2%; Vitamin B1: 0.1-0.5%; Vitamin B2: 0.1-0.5%.

4. The drug according to claim 1, characterized in that The rhinitis care solution is prepared by the following steps: a) Dissolve gentamicin sulfate, dexamethasone sodium phosphate, ribavirin and chlorpheniramine maleate in purified water respectively and stir evenly; b) adding compound ammonium glycyrrhizinate and compound protein peptide in sequence, and mixing evenly under low temperature; c) Filter and sterilize the solution and fill it into nasal drop bottles or spray bottles.

5. The drug according to claim 1, characterized in that The nutritional powder is prepared by the following steps: a) Mix collagen peptide, sea cucumber peptide and taurine in proportion and stir evenly; b) Add vitamin B1 and vitamin B2 to the mixture and continue stirring until evenly dispersed; c) Dry the mixture under vacuum conditions until the moisture content is less than 5%, crush it to a particle size of 50-100 μm, and fill it into packaging bags.

6. The drug according to claim 1, characterized in that When the rhinitis care solution is used in combination with the nutrient powder, the steps are as follows: a) Add the nutrient powder into the rhinitis care solution at a ratio of 1:10; b) Shake thoroughly until evenly mixed and ensure that the nutrient powder is completely dissolved; c) Use the medicine by nasal drops or spray according to the dosage and time prescribed by the doctor to ensure that the liquid medicine evenly covers the nasal mucosa and keeps it moist and nourished for a long time.

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