Preparation equipment and process of bifonazole solution

Abstract

The invention discloses bifonazole solution preparation equipment and technology, and relates to the technical field of solution preparation.The bifonazole solution preparation equipment comprises a tank body, a round cover is fixedly installed on the top face of the tank body, a discharging pipe penetrates through and is fixed to the bottom of the right side of the tank body, a feeding port is formed in the left side of the top face of the round cover, and a liquid inlet pipe is fixed to the right side of the top face of the round cover; an auxiliary material pipe is fixed to the right side of the top face of the round cover and located on the left side of the liquid inlet pipe, a driving module is fixed to the middle of the top face of the round cover and comprises a round shell and a servo motor, the round shell is fixed to the middle of the top face of the round cover, and the servo motor is fixedly installed at the top end in the round shell. According to the device, bubbles in a bifonazole solution are vibrated out through the frame net, so that the problem that the medicinal effect of the bifonazole solution is unqualified due to the fact that a large number of bubbles exist in the bifonazole solution is solved.

Description

Technical Field

[0001] The invention relates to the technical field of solution preparation, in particular to equipment and a process for preparing a bifonazole solution. Background Art

[0002] The appearance of the bifonazole raw material is white to off-white crystalline powder, slightly soluble in water, and easily soluble in organic solvents such as ethanol, dimethyl sulfoxide, etc. The pharmacological action of the bifonazole solution is mainly exerted by inhibiting the synthesis of fungal cell membranes, so that bifonazole has an antibacterial effect on a variety of common dermatophytes and Candida. The main function of the preparation of the bifonazole solution is to prepare the bifonazole raw material into a gel solution, so as to ensure the completeness of the bifonazole reaction and improve the purity of the product.

[0003] The patent number CN115463086B discloses a production process of bifonazole solution, which relates to the technical field of bifonazole solution processing. The bifonazole solution comprises the following raw materials in parts by weight: 0.5-1.5 parts of bifonazole, 10-30 parts of propylene glycol, 3-7 parts of dimethyl sulfoxide, 2-8 parts of glycerol, 20-60 parts of 95% ethanol and 10-18 parts of purified water. The production equipment of the bifonazole solution comprises a stirring drum, wherein the stirring drum comprises a bottom cylinder, a conical top and a control cylinder, and the upper end of the bottom cylinder is fixedly connected to the lower end of the conical top. The invention proposes a production process of bifonazole solution, wherein the prepared bifonazole solution is in a flowing liquid state, is volatile, and relieves the discomfort of the patient. When processing the bifonazole solution, the production equipment of the bifonazole solution is used, and a stirring shaft is arranged to drive the feeding assembly to work simultaneously, so as to improve the uniformity of stirring.

[0004] However, the current production process of bifonazole solution has the following problems: when the production process of bifonazole solution is used, bubbles will be generated in the bifonazole solution during the preparation process of the bifonazole solution, which can easily reduce the medicinal effect of the bifonazole solution, thereby causing the bifonazole solution to have unqualified medicinal effects. Therefore, we propose a bifonazole solution preparation device and process. Summary of the invention

[0005] In view of the deficiencies in the prior art, the present invention provides a bifonazole solution preparation device and process, which solves the problems raised in the above background technology.

[0006] To achieve the above purpose, the present invention is implemented through the following technical scheme: a bifonazole solution preparation device, including a tank body, a round cover is fixedly installed on the top surface of the tank body, a discharge pipe is passed through and fixed on the bottom of the right side of the tank body, a feed port is opened on the left side of the top surface of the round cover, a liquid inlet pipe is fixed on the right side of the top surface of the round cover, an auxiliary material pipe is fixed on the right side of the top surface of the round cover, and the auxiliary material pipe is located on the left side of the liquid inlet pipe, a driving module is fixed in the middle of the top surface of the round cover, and the driving module includes a round shell and a servo motor, the round shell is fixed in the middle of the top surface of the round cover, a servo motor is fixedly installed on the top of the round shell, a round rod is passed through and rotatably installed in the middle of the top surface of the round cover, and the top end of the round rod is fixedly connected to the bottom surface of the servo motor shaft of the driving module, A concave disk is fixed on the bottom surface of the round rod, another concave disk is fixed on the outer wall of the round rod, four frame nets are embedded in the outer walls of the two concave disks respectively, a ring frame is fixed on the top surface of the four frame nets, a circular shell is fixed on the top surface of the ring frame, a plurality of weighted balls are rotatably mounted on the inner wall of the circular shell, an anti-sticking device is arranged on the bottom surface of the ring frame, the anti-sticking device is used to scrape off the bifonazole raw material on the inner wall of the tank body, a turning device is arranged on the inner wall of the anti-sticking device, the turning device is used to turn over the bifonazole raw material at the bottom of the tank body, the weighted ball hits the wall of the circular shell when rolling, the circular shell vibrates, the circular shell transmits the vibration to the ring frame, the ring frame transmits the vibration to the frame net, so that the frame net vibrates out the bubbles in the bifonazole solution when rotating and stirring.

[0007] According to the above technical solution, a bottom frame is fixed to the bottom surface of the tank body, a resistance heater is fixedly installed at the bottom end of the bottom frame, and the resistance heater is located below the tank body.

[0008] According to the above technical solution, a valve is arranged inside the discharge pipe, a connector is arranged at the right end of the discharge pipe, the auxiliary material pipe is located above the liquid inlet pipe, and connectors are arranged on the right sides of the auxiliary material pipe and the liquid inlet pipe.

[0009] According to the above technical solution, the circular shell is sleeved under the round rod, and the four frame nets are suspended inside the tank body.

[0010] According to the above technical solution, four arched rods are fixed to the bottom surface of the ring frame, one end of the four arched rods away from the ring frame is fixedly connected to the bottom surface of the concave plate, four vertical frames are fixed to the outer walls of the four arched rods, and four scraping plates are fixed to the side of the four vertical frames away from the four arched rods, and the outer walls of the four scraping plates are in sliding contact with the inner wall of the tank body. During the rotation of the scraping plates, the scraping plates scrape off the bifonazole raw material attached to the wall of the tank body.

[0011] According to the above technical solution, a number of ring blocks are fixed to the outer walls of the four circular rods, a number of thin rods are fixed to the outer walls of the ring blocks, and one end of the thin rods away from the outer walls of the ring blocks is fixedly connected to the inner walls of the four vertical frames. The thin rods disperse the agglomerated bifonazole raw materials during rotation.

[0012] According to the above technical solution, a porous disk is fixed at the bottom of the outer wall of the four arched rods, a cylinder is fixed in the middle of the bottom surface of the porous disk, the bottom surface of the cylinder is rotatably connected to the bottom end of the tank body, four horizontal plates are fixed at the bottom of the outer wall of the cylinder, four square openings are respectively opened on the outer walls of the four horizontal plates, the bottom surfaces of the four horizontal plates are in sliding contact with the bottom end of the tank body, and during the rotation of the horizontal plates, the horizontal plates sweep the reacted bifonazole solution in the tank body into the discharge pipe.

[0013] According to the above technical solution, ring blocks are fixed on the inner walls of the square openings of the four horizontal plates, four vertical columns are fixed on the top surfaces of the ring blocks, four triangular blocks are fixed on the top surfaces of the four vertical columns, and four square plates are fixed on the inclined surfaces of the four triangular blocks respectively. The triangular blocks drive the square plates to rotate forward, and the square plates flip the bifonazole raw materials under the tank body upwards.

[0014] According to the above technical solution, four square ring rods are respectively fixed to the bottom of the outer walls of the four vertical columns, four short rods are respectively fixed to the ends of the four square ring rods away from the four vertical columns, four sheet plates are respectively fixed to the bottom surfaces of the four short rods, and the outer walls of the four sheet plates are in sliding contact with the inner wall of the tank body at an angle. During the rotation of the sheet plates, the sheet plates scrape away the bifonazole raw materials accumulated at the angle of the tank body.

[0015] A preparation process of a bifonazole solution preparation device comprises the following steps:

[0016] S1. The operator puts the bifonazole raw material into the feed port of the round cover;

[0017] S2, the liquid inlet pipe transports ethanol into the tank body, and the auxiliary material pipe transports dimethyl sulfoxide, glycerol and purified water into the tank body;

[0018] S3, the resistance heater heats the tank;

[0019] S4. When the frame is rotating and stirring, the frame vibrates out the bubbles in the bifonazole solution;

[0020] S5. During the rotation of the scraper plate, the scraper plate scrapes off the bifonazole raw material attached to the wall of the tank body;

[0021] S6, the thin rod disperses the agglomerated bifonazole raw material during the rotation process;

[0022] S7, the square plate turns the bifonazole raw material under the tank upwards;

[0023] S8. During the rotation of the plate, the plate scrapes off the bifonazole raw materials accumulated at the angle of the tank body;

[0024] S9. During the rotation of the horizontal plate, the horizontal plate sweeps the bifonazole solution in the tank into the discharge pipe.

[0025] The present invention provides a bifonazole solution preparation device having the following beneficial effects:

[0026] (1) The present invention comprises a tank body, a discharge pipe, a round cover, a liquid inlet pipe, an auxiliary material pipe, a driving module, a round rod, a concave plate, a frame net, a ring frame and a circular shell with a counterweight ball. During the rotation of the frame net, the frame net stirs the bifonazole raw material, ethanol, methyl sulfoxide, glycerin and purified water in the tank body, the frame net drives the ring frame to rotate forward, and the ring frame drives the circular shell to rotate forward. During the rotation of the circular shell, the counterweight ball hits the wall of the circular shell while rolling, and the circular shell vibrates. The circular shell transmits the vibration to the ring frame, and the ring frame transmits the vibration to the frame net. When the frame net rotates and stirs, the frame net vibrates out the bubbles in the bifonazole solution, thereby preventing a large number of bubbles in the bifonazole solution from causing the bifonazole solution to have an unqualified medicinal effect.

[0027] (2) The present invention arranges an anti-sticking device so that the circular rod, the vertical frame, the scraper plate and the ring block cooperate with the thin rod. During the rotation of the scraper plate, the scraper plate scrapes off the bifonazole raw material attached to the wall of the tank body to prevent a large amount of bifonazole raw material attached to the wall of the tank body from causing incomplete reaction of the bifonazole raw material. During the rotation of the thin rod, the agglomerated bifonazole raw material is dispersed to prevent the agglomeration of the bifonazole raw material from causing poor reaction effect of the bifonazole.

[0028] (3) The present invention sets an anti-sticking device so that the porous disk and the cylinder cooperate with the horizontal plate. During the rotation of the horizontal plate, the horizontal plate sweeps the bifonazole solution in the tank into the discharge pipe to prevent the bifonazole solution from being discharged slowly and causing poor discharge effect of the bifonazole solution.

[0029] (4) The present invention sets a material turning device so that the ring block, the vertical column and the triangular block cooperate with the square plate. The triangular block drives the square plate to rotate forward, and the square plate turns the bifonazole raw material under the tank body upward, thereby preventing the bifonazole raw material from accumulating under the tank body and causing the bifonazole raw material under the tank body to react slowly.

[0030] (5) The present invention arranges the material turning device so that the square ring rod and the short rod cooperate with the plate. During the rotation of the plate, the plate scrapes off the bifonazole raw material accumulated at the angle of the tank body, thereby preventing the bifonazole raw material from accumulating at the angle of the tank body and making it difficult for the bifonazole raw material at the angle of the tank body to react. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 A schematic diagram of the present invention as a whole;

[0032] Figure 2 It is a cross-sectional schematic diagram of the present invention as a whole;

[0033] Figure 3 It is a cross-sectional schematic diagram of the tank body of the present invention;

[0034] Figure 4 is a schematic diagram of the anti-sticking device of the present invention;

[0035] Figure 5 For the present invention Figure 4 A local enlarged schematic diagram of the middle A;

[0036] Figure 6 It is a schematic diagram of the material turning device of the present invention;

[0037] Figure 7 For the present invention Figure 6 A local enlarged schematic diagram of point B in the middle.

[0038] In the figure: 1, bottom frame; 2, resistance heater; 3, tank body; 4, discharge pipe; 5, round cover; 6, liquid inlet pipe; 7, auxiliary material pipe; 8, drive module; 9, round rod; 10, concave disk; 11, frame net; 12, ring frame; 13, circular shell; 14, counterweight ball; 15, anti-sticking device; 151, circular rod; 152, vertical frame; 153, scraper plate; 154, ring block; 155, thin rod; 156, porous disk; 157, cylinder; 158, horizontal plate; 16, turning device; 161, ring block; 162, vertical column; 163, triangle block; 164, square plate; 165, ring square rod; 166, short rod; 167, sheet plate. DETAILED DESCRIPTION

[0039] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0040] See also Figure 1-Figure 7One embodiment of the present invention is: a bifonazole solution preparation device, including a tank body 3, a round cover 5 is fixedly installed on the top surface of the tank body 3, a discharge pipe 4 is penetrated and fixed at the bottom of the right side of the tank body 3, a feed port is opened on the left side of the top surface of the round cover 5, a liquid inlet pipe 6 is fixed on the right side of the top surface of the round cover 5, an auxiliary material pipe 7 is fixed on the right side of the top surface of the round cover 5, and the auxiliary material pipe 7 is located on the left side of the liquid inlet pipe 6, a driving module 8 is fixed in the middle of the top surface of the round cover 5, and the driving module 8 includes a round shell and a servo motor, the round shell is fixed in the middle of the top surface of the round cover 5, the servo motor is fixedly installed at the top of the round shell, and the top of the round shell penetrates and is rotatably installed in the middle of the top surface of the round cover 5 There is a round rod 9, the top of the round rod 9 is fixedly connected to the bottom surface of the servo motor shaft of the driving module 8, a concave disk 10 is fixed to the bottom surface of the round rod 9, another concave disk 10 is fixed to the outer wall of the round rod 9, and the outer walls of the two concave disks 10 are respectively embedded with four frame nets 11, and the top surfaces of the four frame nets 11 are fixed with ring frames 12, and the top surfaces of the ring frames 12 are fixed with a circular shell 13, and the inner wall of the circular shell 13 is rollingly installed with a number of weighted balls 14, a valve is arranged inside the discharge pipe 4, and a connecting piece is arranged at the right end of the discharge pipe 4, the auxiliary material pipe 7 is located above the liquid inlet pipe 6, and a connecting piece is arranged on the right side of the auxiliary material pipe 7 and the liquid inlet pipe 6, and the circular shell 13 is provided with a plurality of weighted balls 14. The shell 13 is sleeved under the round rod 9, and four frame nets 11 are suspended inside the tank body 3. The bottom surface of the ring frame 12 is provided with an anti-sticking device 15, and the anti-sticking device 15 is used to scrape the bifonazole raw material on the inner wall of the tank body 3. The inner wall of the anti-sticking device 15 is provided with a turning device 16, and the turning device 16 is used to turn over the bifonazole raw material at the bottom of the tank body 3. The bottom surface of the tank body 3 is fixed with a bottom frame 1, and a resistance heater 2 is fixedly installed at the bottom end of the bottom frame 1. The resistance heater 2 is located below the tank body 3. During the rotation of the frame net 11, the frame net 11 can turn over the bifonazole raw material, ethanol, methyl sulfoxide, glycerol and pure The frame net 11 drives the ring frame 12 to rotate forward, and the ring frame 12 drives the circular shell 13 to rotate forward. During the rotation of the circular shell 13, the counterweight ball 14 in the circular shell 13 starts to roll, and the counterweight ball 14 hits the wall of the circular shell 13 during rolling, so that the circular shell 13 vibrates, and the circular shell 13 transmits the vibration to the ring frame 12, and the ring frame 12 transmits the vibration to the frame net 11. When the frame net 11 rotates and stirs, the frame net 11 vibrates out the bubbles in the bifonazole solution, so as to avoid a large number of bubbles in the bifonazole solution when the solution preparation equipment is in use, resulting in unqualified medicinal effect of the bifonazole solution.

[0041] During the preparation of the bifonazole solution, bubbles are generated in the bifonazole solution, which may reduce the medicinal effect of the bifonazole solution. When preparing the bifonazole solution, the operator puts the bifonazole raw material into the feed port of the round cover 5, and the bifonazole raw material enters the tank body 3. At the same time, the bottom frame 1 supports the tank body 3, and the liquid inlet pipe 6 transports ethanol into the tank body 3. At the same time, the auxiliary material pipe 7 transports dimethyl sulfoxide, glycerol and purified water into the tank body 3. The operator starts the resistance heater 2 in the bottom frame 1, and the resistance heater 2 heats the tank body 3. The operator starts the driving module 8 on the round cover 5, and the servo motor shaft in the driving module 8 starts to rotate forward. The servo motor shaft drives the round rod 9 to rotate forward, and the round rod 9 drives the concave plate 10 to rotate forward. The concave plate 10 drives the frame net 11 to rotate forward. The frame net 11 During the rotation, the frame net 11 stirs the bifonazole raw material, ethanol, methyl sulfoxide, glycerin and purified water in the tank body 3. At the same time, the frame net 11 drives the ring frame 12 to rotate forward, and the ring frame 12 drives the circular shell 13 to rotate forward. During the rotation of the circular shell 13, the counterweight ball 14 in the circular shell 13 starts to roll, and the counterweight ball 14 hits the wall of the circular shell 13 when rolling, and the circular shell 13 vibrates. The circular shell 13 transmits the vibration to the ring frame 12, and the ring frame 12 transmits the vibration to the frame net 11. When the frame net 11 rotates and stirs, the frame net 11 vibrates out the bubbles in the bifonazole solution, preventing a large number of bubbles in the bifonazole solution when the equipment is in use, thereby avoiding the problem that a large number of bubbles in the bifonazole solution when the solution preparation equipment is in use causes the bifonazole solution to have an unqualified medicinal effect.

[0042] See also Figure 1-Figure 7 On the basis of the above embodiment, in another embodiment of the present invention, four reciprocating rods 151 are respectively fixed to the bottom surface of the ring frame 12, and one end of the four reciprocating rods 151 away from the ring frame 12 is fixedly connected to the bottom surface of the concave plate 10, and four vertical frames 152 are respectively fixed to the outer walls of the four reciprocating rods 151, and four scraping strips 153 are respectively fixed to the side of the four vertical frames 152 away from the four reciprocating rods 151, and the outer walls of the four scraping strips 153 are in sliding contact with the inner wall of the tank body 3. During the rotation of the scraping strips 153, the scraping strips 153 scrape off the bifonazole original attached to the wall surface of the tank body 3. In order to avoid incomplete reaction of the bifonazole raw material due to a large amount of bifonazole raw material attached to the wall of the tank body 3 when the solution preparation equipment is in use, a number of ring blocks 154 are fixed to the outer walls of the four arched rods 151, and a number of thin rods 155 are fixed to the outer walls of the ring blocks 154, respectively. One end of the thin rods 155 away from the outer walls of the ring blocks 154 is fixedly connected to the inner walls of the four vertical frames 152. The thin rods 155 disperse the agglomerated bifonazole raw material during rotation, so as to avoid poor reaction effect of the bifonazole raw material due to agglomeration of the bifonazole raw material when the solution preparation equipment is in use.

[0043] A porous disk 156 is fixed to the bottom of the outer wall of the four arched rods 151, and a cylinder 157 is fixed in the middle of the bottom of the porous disk 156. The bottom of the cylinder 157 is rotatably connected to the bottom of the tank body 3. Four horizontal plates 158 are fixed to the bottom of the outer wall of the cylinder 157. Four square openings are respectively opened on the outer walls of the four horizontal plates 158. The bottom surfaces of the four horizontal plates 158 are in sliding contact with the bottom of the tank body 3. During the rotation of the horizontal plates 158, the horizontal plates 158 sweep the reacted bifonazole solution in the tank body 3 into the discharge pipe 4, so as to avoid the bifonazole solution being discharged slowly when the solution preparation equipment is in use, resulting in poor discharge effect of the bifonazole solution.

[0044] A ring block 161 is fixed to the inner wall of the square opening of the four horizontal plates 158, four vertical columns 162 are fixed to the top surface of the ring block 161, four triangular blocks 163 are fixed to the top surfaces of the four vertical columns 162, and four square plates 164 are fixed to the inclined surfaces of the four triangular blocks 163 respectively. The triangular blocks 163 drive the square plates 164 to rotate forward, and the square plates 164 flip the bifonazole raw material under the tank body 3 upward to avoid the bifonazole raw material accumulating under the tank body 3 when the solution preparation equipment is in use, causing the bifonazole raw material under the tank body 3 to react slowly.

[0045] Four square ring rods 165 are fixed to the bottom of the outer walls of the four vertical columns 162, and four short rods 166 are fixed to the ends of the four square ring rods 165 away from the four vertical columns 162. Four plates 167 are fixed to the bottom surfaces of the four short rods 166. The outer walls of the four plates 167 are in sliding contact with the inner wall angle of the tank body 3. During the rotation of the plates 167, the plates 167 scrape off the bifonazole raw materials accumulated at the angle of the tank body 3 to avoid the bifonazole raw materials accumulated at the angle of the tank body 3 when the solution preparation equipment is in use, which makes it difficult for the bifonazole raw materials at the angle of the tank body 3 to react.

[0046] A preparation process of a bifonazole solution preparation device comprises the following steps:

[0047] S1, the operator puts the bifonazole raw material into the feed port of the round cover 5;

[0048] S2, the liquid inlet pipe 6 transports ethanol into the tank body 3, and the auxiliary material pipe 7 transports dimethyl sulfoxide, glycerol and purified water into the tank body 3;

[0049] S3, the resistance heater 2 heats the tank 3;

[0050] S4, when the frame net 11 is rotating and stirring, the frame net 11 vibrates out the bubbles in the bifonazole solution;

[0051] S5. During the rotation of the scraper plate 153, the scraper plate 153 scrapes off the bifonazole raw material attached to the wall of the tank body 3;

[0052] S6, the thin rod 155 disperses the agglomerated bifonazole raw material during the rotation process;

[0053] S7, the square plate 164 turns the bifonazole raw material below the tank body 3 upward;

[0054] S8, during the rotation of the plate 167, the plate 167 scrapes off the bifonazole raw material accumulated at the angle of the tank body 3;

[0055] S9. During the rotation of the horizontal plate 158, the horizontal plate 158 sweeps the bifonazole solution in the tank body 3 into the discharge pipe 4.

[0056] While the frame net 11 drives the ring frame 12 to rotate forward, the ring frame 12 drives the return rod 151 to rotate forward, the return rod 151 drives the vertical frame 152 to rotate forward, and the vertical frame 152 drives the scraper plate 153 to rotate forward. During the rotation of the scraper plate 153, the scraper plate 153 scrapes off the bifonazole raw material attached to the wall of the tank body 3 to prevent a large amount of bifonazole raw material from being attached to the wall of the tank body 3 when the equipment is in use, thereby avoiding the problem of incomplete reaction of the bifonazole raw material caused by a large amount of bifonazole raw material attached to the wall of the tank body 3 when the solution preparation equipment is in use. At the same time, the return rod 151 drives the ring block 154 to rotate forward, and the ring block 154 drives the thin rod 155 to rotate forward. During the rotation, the thin rod 155 disperses the agglomerated bifonazole raw material to prevent the bifonazole raw material from agglomerating when the equipment is in use, thereby avoiding the problem of poor bifonazole reaction effect caused by agglomeration of the bifonazole raw material when the solution preparation equipment is in use.

[0057] While the ring frame 12 drives the return rod 151 to rotate forward, the return rod 151 drives the porous disk 156 to rotate forward, the porous disk 156 drives the cylinder 157 to rotate forward, and the cylinder 157 drives the cross plate 158 to rotate forward. During the rotation of the cross plate 158, the cross plate 158 sweeps the reacted bifonazole solution in the tank body 3 into the discharge pipe 4 to prevent the bifonazole solution from being discharged slowly when the equipment is in use, thereby avoiding the problem of poor discharge effect of the bifonazole solution caused by the slow discharge of the bifonazole solution when the solution preparation equipment is in use.

[0058] While the cylinder 157 drives the horizontal plate 158 to rotate forward, the horizontal plate 158 drives the ring block 161 to rotate forward, the ring block 161 drives the vertical column 162 to rotate forward, the vertical column 162 drives the triangular block 163 to rotate forward, the triangular block 163 drives the square plate 164 to rotate forward, and the square plate 164 flips the bifonazole raw material under the tank body 3 upward to prevent the bifonazole raw material from accumulating under the tank body 3 when the equipment is in use, thereby avoiding the problem of slow reaction of the bifonazole raw material under the tank body 3 caused by the accumulation of the bifonazole raw material under the tank body 3 when the solution preparation equipment is in use.

[0059] While the ring block 161 drives the vertical column 162 to rotate forward, the vertical column 162 drives the square ring rod 165 to rotate forward, the square ring rod 165 drives the short rod 166 to rotate forward, and the short rod 166 drives the plate 167 to rotate forward. During the rotation of the plate 167, the plate 167 scrapes away the bifonazole raw material accumulated at the corner of the tank body 3 to prevent the bifonazole raw material from accumulating at the corner of the tank body 3 when the equipment is in use, thereby avoiding the problem that the bifonazole raw material at the corner of the tank body 3 is difficult to react when the solution preparation equipment is in use.

[0060] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A bifonazole solution preparation device, comprising a tank body (3), a round cover (5) fixedly mounted on the top surface of the tank body (3), characterized in that: A discharge pipe (4) is passed through and fixed to the bottom of the right side of the tank body (3); a feed port is opened on the left side of the top surface of the round cover (5); a liquid inlet pipe (6) is fixed to the right side of the top surface of the round cover (5); an auxiliary material pipe (7) is fixed to the right side of the top surface of the round cover (5); the auxiliary material pipe (7) is located on the left side of the liquid inlet pipe (6); a driving module (8) is fixed in the middle of the top surface of the round cover (5); a round rod (9) is passed through and rotatably installed in the middle of the top surface of the round cover (5); the top end of the round rod (9) is fixedly connected to the bottom surface of the servo motor shaft of the driving module (8); a concave disk (10) is fixed to the bottom surface of the round rod (9); and the outer wall of the round rod (9) is fixed There is another concave plate (10), and the outer walls of the two concave plates (10) are respectively embedded with four frame nets (11), and the top surfaces of the four frame nets (11) are fixed with a ring frame (12), and the top surface of the ring frame (12) is fixed with a circular shell (13), and the inner wall of the circular shell (13) is rotatably mounted with a plurality of weighted balls (14), and the bottom surface of the ring frame (12) is provided with an anti-sticking device (15), and the anti-sticking device (15) is used to scrape off the bifonazole raw material on the inner wall of the tank body (3), and the inner wall of the anti-sticking device (15) is provided with a material turning device (16), and the material turning device (16) is used to turn over the bifonazole raw material at the bottom of the tank body (3).

2. A bifonazole solution preparation device according to claim 1, characterized in that: A bottom frame (1) is fixed to the bottom surface of the tank body (3), and a resistance heater (2) is fixedly installed at the bottom end of the bottom frame (1), and the resistance heater (2) is located below the tank body (3).

3. A bifonazole solution preparation device according to claim 2, characterized in that: A valve is provided inside the discharge pipe (4), a connecting piece is provided at the right end of the discharge pipe (4), the auxiliary material pipe (7) is located above the liquid inlet pipe (6), and connecting pieces are provided on the right sides of the auxiliary material pipe (7) and the liquid inlet pipe (6).

4. A bifonazole solution preparation device according to claim 3, characterized in that: The circular shell (13) is sleeved under the round rod (9), and the four frame nets (11) are suspended inside the tank body (3).

5. A bifonazole solution preparation device according to claim 4, characterized in that: Four reciprocating rods (151) are fixed to the bottom surface of the ring frame (12), one end of the four reciprocating rods (151) away from the ring frame (12) is fixedly connected to the bottom surface of the concave plate (10), four vertical frames (152) are fixed to the outer walls of the four reciprocating rods (151), four scraping strips (153) are fixed to the sides of the four vertical frames (152) away from the four reciprocating rods (151), and the outer walls of the four scraping strips (153) are in sliding contact with the inner wall of the tank body (3).

6. The bifonazole solution preparation device according to claim 5, characterized in that: A plurality of ring blocks (154) are respectively fixed to the outer walls of the four circular rods (151), a plurality of thin rods (155) are respectively fixed to the outer walls of the plurality of ring blocks (154), and one end of the plurality of thin rods (155) away from the outer walls of the plurality of ring blocks (154) is fixedly connected to the inner walls of the four vertical frames (152).

7. A bifonazole solution preparation device according to claim 6, characterized in that: A porous disk (156) is fixed at the bottom of the outer wall of the four circular rods (151), a cylinder (157) is fixed in the middle of the bottom surface of the porous disk (156), the bottom surface of the cylinder (157) is rotatably connected to the bottom end of the inner part of the tank body (3), four horizontal plates (158) are fixed at the bottom of the outer wall of the cylinder (157), the outer walls of the four horizontal plates (158) are respectively provided with four square openings, and the bottom surfaces of the four horizontal plates (158) are in sliding contact with the inner bottom end of the tank body (3).

8. The bifonazole solution preparation device according to claim 7, characterized in that: A ring block (161) is fixed to the inner wall of the square opening of the four horizontal plates (158), four vertical columns (162) are fixed to the top surface of the ring block (161), four triangular blocks (163) are fixed to the top surfaces of the four vertical columns (162), and four square plates (164) are fixed to the inclined surfaces of the four triangular blocks (163), respectively.

9. The bifonazole solution preparation device according to claim 8, characterized in that: Four square ring rods (165) are respectively fixed to the bottom of the outer walls of the four vertical columns (162); four short rods (166) are respectively fixed to one end of the four square ring rods (165) away from the four vertical columns (162); four plates (167) are respectively fixed to the bottom surfaces of the four short rods (166); and the outer walls of the four plates (167) are in sliding contact with the inner wall of the tank body (3) at an angle.

10. The preparation process of a bifonazole solution preparation device according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1. The operator puts the bifonazole raw material into the feed port of the round cover (5); S2, the liquid inlet pipe (6) transports ethanol into the tank body (3), and the auxiliary material pipe (7) transports dimethyl sulfoxide, glycerol and purified water into the tank body (3); S3, the resistance heater (2) heats the tank body (3); S4, when the frame net (11) is rotating and stirring, the frame net (11) vibrates out the bubbles in the bifonazole solution; S5, during the rotation of the scraper plate (153), the scraper plate (153) scrapes off the bifonazole raw material attached to the wall surface of the tank body (3); S6, the thin rod (155) disperses the agglomerated bifonazole raw material during the rotation process; S7, the square plate (164) turns the bifonazole raw material below the tank body (3) upwards; S8, during the rotation of the plate (167), the plate (167) scrapes off the bifonazole raw material accumulated at the angle of the tank body (3); S9. During the rotation of the horizontal plate (158), the horizontal plate (158) sweeps the bifonazole solution in the tank (3) that has reacted into the discharge pipe (4).

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