Moisturizing and whitening composition capable of promoting permeation and absorption and application of moisturizing and whitening composition in skin care products

Abstract

The invention relates to a moisturizing and whitening composition for promoting permeation and absorption and application of the moisturizing and whitening composition in skin care products. The composition comprises phospholipid polyethylene glycol carboxyl, limonene, menthone and other penetration enhancer components, and by optimizing the composition and proportion of the penetration enhancer, the skin permeability of phytoestrogen is remarkably improved. After a skin care product prepared from the composition is used for 4 hours, the water content of skin is stably maintained to be 60% or above, meanwhile, the skin care product is excellent in whitening, skin elasticity improving and other aspects, the skin brightness change (L) is remarkably improved, and the skin elasticity growth rate exceeds 26% after the skin care product is used for 5 weeks. The composition solves the problem of low permeation efficiency of phytoestrogen, realizes the effects of long-acting moisturizing, whitening and the like, has good use experience, is free of irritation and anaphylaxis, and has a wide market application prospect.

Description

Technical Field

[0001] The present invention belongs to the technical field of skin care products, and particularly relates to a moisturizing and whitening composition capable of promoting penetration and absorption and its application in skin care products. Background Art

[0002] Most of the current skin care products on the market can only act on the skin surface. Although they can quickly replenish water, because the effective moisturizing ingredients are difficult to penetrate into the stratum corneum and the water is easily evaporated, the skin quickly becomes dehydrated again, making it difficult to achieve long-term moisturizing, whitening and anti-wrinkle effects. Phytoestrogens, especially soy isoflavones present in leguminous plants, have attracted wide attention because they can bind to estrogen receptors and exhibit multiple physiological functions such as bidirectionally regulating the estrogen level in women's bodies, improving menopausal symptoms, osteoporosis and cardiovascular diseases, and also have significant effects in beauty care such as antioxidant and anti-aging, improving skin quality, and making the skin smooth and elastic.

[0003] However, skin care products usually rely on natural penetration to enable active ingredients to enter the skin. However, the natural barrier function of the stratum corneum results in low absorption efficiency of active ingredients, and most of them remain on the skin surface, making it difficult to exert deep effects. Although chemical penetration enhancers can increase the penetration amount, the risk of their irritation and side effects makes it necessary to develop safe penetration enhancement technologies. The molecular weight of skin-penetrating substances is usually below 500 Da, but the penetration efficiency of low-molecular-weight substances is not necessarily high, and the penetration efficiency of high-molecular-weight substances such as growth factors is even lower. This makes the cosmetics industry in urgent need of safe and effective methods for delivering bioactive substances.

[0004] The application of phytoestrogens in cosmetics or skin care products can improve the skin health status from multiple dimensions such as moisturizing, whitening and anti-aging. However, phytoestrogens cannot penetrate well into the skin stratum corneum, and the main reasons are as follows:

[0005] (1) Skin barrier function: The stratum corneum is composed of multiple layers of keratinocytes and lipids. Its tightly arranged structure forms a natural barrier that can effectively prevent the invasion of external substances, including phytoestrogens. In particular, phytoestrogens with larger molecular weights or stronger polarities are more difficult to penetrate this barrier. (2) Molecular property limitations and poor water solubility: Some phytoestrogens have relatively large molecular weights. For example, the molecular weight of puerarin is 416 Da, and its relatively large molecular volume makes it difficult to pass through the tiny gaps between stratum corneum cells, thus restricting its penetration in the skin. Some phytoestrogens have poor water solubility and are not easily dissolved and dispersed on the skin surface, making it difficult to enter the stratum corneum through the aqueous channels of the skin. The stratum corneum of the skin is mainly composed of lipids and keratin and has a certain degree of hydrophobicity, which limits the permeability of water-soluble phytoestrogens. (3) Concentration issue in use: In skin care products, the concentration of phytoestrogens is usually limited. Too low a concentration may result in insufficient penetration on the skin surface and difficulty in achieving significant effects.

[0006] Therefore, in the process of realizing the efficacy of cosmetics, it is an urgent problem to be solved to promote the penetration ability of phytoestrogen active substances in the skin barrier, improve stability, and reduce irritation by optimizing the penetration-enhancing technology without damaging the skin barrier. Summary of the Invention

[0007] The object of the present invention is to provide a moisturizing and whitening composition that can effectively promote penetration and absorption and its application in skin care in view of the above problems. By optimizing the composition and ratio of the penetration enhancer without irritating or damaging the skin, the penetration ability of phytoestrogen active substances in the skin barrier is significantly improved, and the problems of low penetration efficiency of phytoestrogens and skin barrier damage in the prior art are well solved.

[0008] The present invention relates to a moisturizing and whitening composition that promotes penetration and absorption, comprising the following raw material components in parts by weight: 1-15 parts of a penetration enhancer, 5-10 parts of phytoestrogen powder, 1-5 parts of polypeptide, and 1-8 parts of biosurfactant.

[0009] Preferably, the penetration enhancer is phospholipid polyethylene glycol carboxyl, limonene, and menthone, and the mass ratio of phospholipid polyethylene glycol carboxyl, limonene, and menthone is 5-10:1-5:0.5-1.

[0010] Preferably, the molecular weight of polyethylene glycol in the phospholipid polyethylene glycol carboxyl is 300-3000. Further preferably, the molecular weight of polyethylene glycol (PEG) in the phospholipid polyethylene glycol carboxyl is 750-2000.

[0011] Preferably, the polypeptide is one or more of acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7.

[0012] Preferably, the phytoestrogen powder is at least one of red clover extract, soybean stem extract, flax seed extract, and kudzu root extract. Particularly preferably, the phytoestrogen powder is a combination of red clover extract, soybean stem extract, flax seed extract, and kudzu root extract in a mass ratio of 1:2-3:1-3:0.5-1.

[0013] Preferably, the biosurfactant is at least one of sodium cocoyl glutamate, lecithin, coco-glucoside, cocamidopropyl betaine, and cocamidopropyl hydroxybetaine.

[0014] The application of phospholipid polyethylene glycol carboxyl (DSPE-PEG-COOH) used in the present invention in cosmetics or skin care products is mainly based on its unique chemical structure and properties. The phospholipid part gives it good biocompatibility and cell membrane permeability, and as a carrier of active ingredients in skin care products, it improves its stability and bioavailability; the terminal carboxyl group can be coupled with a variety of bioactive molecules through covalent bonds to achieve functional modification, thereby enhancing the efficacy of cosmetics or skin care products. At the same time, it has good biocompatibility and safety, will not irritate the skin, and will not cause allergic reactions. It can be used as an ingredient in products such as moisturizing creams, essences, and foundations to improve the moisturizing effect, dispersibility, and stability of the products. DSPE-PEG-COOH is also an amphiphilic macromolecule. The hydrophobic phospholipid (DSPE) part can be embedded in the lipid structure of the skin stratum corneum, and the hydrophilic PEG chain forms a hydrophilic barrier to prolong the retention time of the active ingredients in the skin surface. The terminal carboxyl group (-COOH) can bind to estrogen through hydrogen bonds to enhance the permeability of phytoestrogens.

[0015] In the penetration enhancer of the present invention, phospholipid polyethylene glycol carboxyl, limonene, and menthone cooperate with each other to enhance phytoestrogens to penetrate the stratum corneum more effectively and enter the deep layer of the skin to play a role. The excessive or low content of phospholipid polyethylene glycol carboxyl, limonene, and menthone has a significant impact on the permeability of phytoestrogens and the performance of skin care products. The mass ratio of 3-10:1-5:0.5-1 can better promote the permeability of phytoestrogens. Too high a concentration of phospholipid polyethylene glycol carboxyl will hinder the interaction between phytoestrogens and cell membranes and reduce the permeation efficiency; too low a concentration will not effectively enhance the stability of phytoestrogens and improve their interaction with cell membranes. Too high a concentration of limonene will destroy the structure of the stratum corneum of the skin, hinder the penetration of phytoestrogens, and may cause irritation reactions, reduce user experience, and even cause allergies; too low a concentration will promote limited permeation effects. Too high a concentration of menthone will cause skin irritation, such as itching, stinging, erythema, etc., which will cause discomfort to users, disrupt the absorption function of skin cells, reduce the permeation effect of phytoestrogens, and affect the user's comfort and satisfaction with skin care products.

[0016] The present invention preferably uses sodium cocoyl glutamate, lecithin, cocoyl glucoside, cocamidopropyl betaine, cocamidopropyl hydroxybetaine surfactants as dispersants. Compared with other types of surfactants, these biosurfactants can not only effectively promote the dispersion and penetration of phytoestrogens in skin care products, but also be more gentle and non-irritating to the skin. At the same time, they have a certain moisturizing ability, can form a protective film on the skin surface, reduce water loss, and keep the skin moisturized.

[0017] The limonene and menthone penetration enhancers of the present invention can expand the permeability of the intercellular channels of the stratum corneum to achieve efficient transdermal estrogen. However, expanding the stratum corneum for a long time to increase the permeability will damage the skin. Therefore, the present invention adds a polypeptide component to the penetration enhancing composition. The structure of the polypeptide is similar to components such as proteins and amino acids in the skin, and can interact with related components in the stratum corneum of the skin, and can repair the stratum corneum enlarged by limonene and menthone, and repair the skin barrier. At the same time, the polypeptide has a certain moisturizing ability, can absorb and lock moisture, increase the water content of the skin, and make the stratum corneum of the skin more moisturized and soft.

[0018] The penetration-enhancing composition for promoting estrogen absorption of the present invention works synergistically through multiple mechanisms: DSPE-PEG-COOH acts as a carrier of phytoestrogen active ingredients to enhance the penetration performance of phytoestrogen; limonene and limonone can expand the permeability of the channels between stratum corneum cells, and the peptides repair the skin barrier, thereby jointly achieving efficient penetration of estrogen and completing the repair of stratum corneum cells.

[0019] Further, among the phytoestrogens used in the present invention, the isoflavone compounds in the red clover extract, the soy isoflavones in the soybean stem extract, the lignans in the flax seed extract, and the puerarin in the kudzu root extract all have phytoestrogen functions. These ingredients can mimic the effects of estrogen, regulate hormone levels, and have a positive impact on skin health. In addition to playing the role of phytoestrogens in skin care products, red clover extract can also be antioxidant, anti-inflammatory and soothing, suitable for sensitive skin; soybean stem extract can promote collagen synthesis, moisturizing and nourishing; flax seed extract has strong moisturizing, repair and regeneration; kudzu root extract has antioxidant, anti-inflammatory and microcirculation improvement effects. It is particularly preferred that the combination of red clover extract, soybean stem extract, flax seed extract, and kudzu root extract is 1:2-3:1-3:0.5-1, and the combination of four phytoestrogen powders can further improve skin moisturizing, delay skin aging, and enhance skin care effects.

[0020] Furthermore, the present invention provides the use of the above-mentioned composition for promoting the absorption of phytoestrogens in skin care products, wherein the added amount of the components of the composition for promoting the absorption of estrogen is 1wt% to 50wt%, and the dosage form of the skin care product includes any one of a cream, an emulsion, an aqueous solution, a facial mask or a lotion.

[0021] Further, in some embodiments of the present invention, the present invention also provides a skin care product with moisturizing and whitening effects, and the skin care product contains 1-50 wt% of a penetration enhancer composition.

[0022] Further, the skin care product further includes 1-15 wt% of a humectant, 3-8 wt% of a soothing agent, 0.5-2 wt% of an emollient, 0.5-2 wt% of a thickener, 0.1-2 wt% of a pH regulator, 0.1-1.5 wt% of an antibacterial agent, and the balance is water.

[0023] Preferably, the humectant is selected from at least one of butylene glycol, glycerin, dipropylene glycol, sodium hyaluronate, and niacinamide.

[0024] Preferably, the soothing agent is selected from any one or a combination of at least two of sialic acid, mannitol, trehalose, and ascorbic acid.

[0025] Preferably, the emollient is selected from at least one of polydimethylsiloxane, polydimethylsiloxanol, hydrogenated polyisobutene, cyclopentasiloxane, and isononyl isononanoate.

[0026] Preferably, the thickener is selected from one or a combination of xanthan gum, carbomer, sodium polyacrylate, or hydroxyethyl cellulose.

[0027] Preferably, the pH regulator is selected from one or a combination of triethanolamine, sodium citrate, and disodium hydrogen phosphate.

[0028] Preferably, the antibacterial agent is selected from one or a combination of phenoxyethanol and p-hydroxyacetophenone.

[0029] Furthermore, the present invention also includes a preparation method of a skin care product, which includes the following steps: mixing each component uniformly in deionized water under stirring conditions to obtain a skin care product with moisturizing and whitening effects.

[0030] The advantages or beneficial effects in the above technical solutions at least include:

[0031] The penetration enhancer composition of the present invention can effectively deliver the phytoestrogen active ingredient to the deep layer of the skin, providing excellent skin permeability and excellent affinity effect, and at the same time not irritating or damaging the skin. Applying the penetration enhancer composition to skin care products can achieve multiple effects such as long-term moisturizing, increased elasticity, and whitening, and can achieve precise and continuous release of active ingredients, thereby bringing more precise skin care effects.

[0032] The above summary is for the purpose of description only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments and features described above, further aspects, embodiments and features of the present application will be readily apparent by referring to the following detailed description. DETAILED DESCRIPTION

[0033] In order to better illustrate the purpose, technical solution and advantages of the present invention, the technical solution of the present invention is further described below through specific implementation methods. However, the following examples are only simple examples of the present invention and do not represent or limit the scope of protection of the present invention. The scope of protection of the present invention shall be subject to the claims.

[0034] The materials and reagents used in the following examples and comparative examples are commercially available unless otherwise specified. The amounts of the components in the following examples are 1 g per part by weight or per portion unless otherwise specified.

[0035] Experimental Materials:

[0036] Phospholipid polyethylene glycol carboxyl 1#, DSPE-PEG350-COOH, Xi'an Qiyue Biological, product number Q-0240084, polyethylene glycol is PEG350.

[0037] Phospholipid polyethylene glycol carboxyl 2#, DSPE-PEG750-COOH, Xi'an Qiyue Biological, product number Q-0240392, polyethylene glycol is PEG750.

[0038] Phospholipid polyethylene glycol carboxyl 3#, DSPE-PEG1000-COOH, Xi'an Qiyue Biological, product number Q-0240524, polyethylene glycol is PEG1000.

[0039] Phospholipid polyethylene glycol carboxyl 4#, DSPE-PEG2000-COOH, Xi'an Qiyue Biological, product number Q-0275221, polyethylene glycol is PEG2000.

[0040] Phospholipid polyethylene glycol carboxyl 5#, DSPE-PEG3000-COOH, Xi'an Qiyue Biological, product number Q-0275223, polyethylene glycol is PEG3000.

[0041] Phytoestrogen powder 1#, red clover extract, were purchased from Shaanxi New Horizon Biotechnology Co., Ltd.

[0042] Phytoestrogen powder 2#, soybean stem extract, was purchased from Nanjing Dosfu Biotechnology Co., Ltd.

[0043] Phytoestrogen powder 3#, Pueraria root extract, was purchased from Xi'an Tianyi Biotechnology Co., Ltd.

[0044] Phytoestrogen powder 4#, and the flaxseed extract was purchased from Ashland.

[0045] Phytoestrogen powder 5# is composed of red clover extract, soybean stem extract, kudzu root extract, and kudzu root extract mixed in a mass ratio of 1:2:1:1.

[0046] The examples and comparative examples respectively relate to a moisturizing and whitening skin care lotion, including material A and material B. Material A is a penetration-enhancing composition containing a phytoestrogen absorption promoter, and material B is composed of a humectant, a soothing agent, an emollient, a thickener, a pH regulator, an antibacterial agent, and water. The raw materials of component B are composed by mass parts as follows: 2 g of glycerol, 1 g of niacinamide, 5 g of sialic acid, 1 g of polydimethylsiloxane, 1 g of xanthan gum, 0.5 g of sodium citrate, 0.3 g of phenoxyethanol, and 100 g of deionized water.

[0047] The preparation method includes the following steps:

[0048] According to the raw material ratios in Table 1 or Table 2, under stirring conditions, each component is mixed evenly in deionized water to prepare a moisturizing and whitening skin care product.

[0049] Table 1: The mass parts (g) of each component in Examples 1-9 are as follows:

[0050]

[0051] Table 2: The raw material mass parts (g) of Comparative Examples 1-8 are composed as follows:

[0052]

[0053] Performance evaluation:

[0054] 1. Transdermal absorption experiment of the sample:

[0055] The estrogen in the soybean stem extract is mainly daidzein. In the transdermal absorption experiment, the examples and comparative examples of phytoestrogen powder 2# (soybean stem extract) were tested. The main test methods are as follows:

[0056] Porcine skin was used to simulate human epidermal skin. The porcine skin was cut into pieces of 10 cm * 5 cm size with scissors, and then soaked in physiological saline for 30 min and used as the transdermal barrier. The tested cosmetic was used as the transdermal release solution, and 30% ethanol - physiological saline was used as the transdermal absorption solution. The transdermal absorption test was carried out under the conditions of constant temperature of 37 °C and constant speed of 500 r / min. At the sampling point after 24 h, 5 mL of the permeate was respectively pipetted with a clean syringe, and then 5 mL of 30% ethanol - physiological saline was supplemented with a clean syringe. The flavonoid content in the sample was determined by high performance liquid chromatography.

[0057] Flavonoid transmittance = (amount of flavonoid in the receiving pool / amount of flavonoid in the emulsion) × 100%.

[0058] Table 3: Results of in vitro percutaneous absorption test

[0059]

[0060] From the test results in Table 3, it can be found that the skin care lotion prepared in Example 2 of the present invention exhibits a significantly higher in vitro percutaneous penetration amount than that of the comparative example. It shows that the three components of phospholipid polyethylene glycol carboxyl, limonene and menthone in the present invention, when combined in a specific mass ratio, can synergistically enhance the skin penetration performance of phytoestrogens. This improvement is beneficial for phytoestrogens to more efficiently penetrate the stratum corneum and then penetrate deep into the skin to fully exert their efficacy.

[0061] 2. Determination of long-term moisturizing performance

[0062] Healthy female volunteers aged 35 - 55 years old were randomly divided into 17 groups, with 5 people in each group. They were respectively used the skin care lotions provided by the examples and the comparative examples. At 0 h, 1 h, and 4 h, a skin moisture tester (Corneometer CM825) was used to quantitatively detect the water content of the facial skin. By comparing the water content changes before and after use, the long-term moisturizing ability of the products was evaluated to characterize whether phytoestrogens penetrated through the skin barrier and entered the deep layer of the skin. Among them, the water content rate and the moisturizing rate were the average values of each group of subjects. Moisturizing rate after 1 h / % = water content rate at 1 h / water content rate at 0 h * 100; Moisturizing rate after 4 h / % = water content rate at 4 h / water content rate at 0 h * 100.

[0063] Table 4: Moisturizing performance test

[0064]

[0065] According to the test data in Table 4, the skin moisturizing rates of the skin care lotions of the examples and the comparative examples were similar after 1 hour of use. However, after 4 hours of use, the lotion of the example could keep the skin water content stably above 60%, while the lotion of the comparative example led to a significant decrease in the skin water content rate. This may be because the penetration enhancer used in the example promoted the penetration of phytoestrogens deep into the skin and continuously released active ingredients on the skin surface, thus achieving a long-term skin care effect.

[0066] 3. Whitening test

[0067] Experimental method: Healthy female volunteers aged 35 - 55 years old were randomly and evenly divided into 17 groups (5 people in each group). Each group was respectively used the skin care products of the examples and the comparative examples for 30 days, once in the morning and once in the evening. A color difference meter was used to measure and calculate the average value of the skin brightness change (△L) before and after use. The results are shown in Table 5.

[0068] Table 5: Whitening Test Results

[0069]

[0070] As shown in Table 5, the skin care lotions prepared in Examples 1-9 showed significant advantages in terms of skin brightness change (△L) and had good whitening effects. By comparing Examples 2, 5-8, it can be seen that DSPE-PEG-COOH with low molecular weight PEG has better permeability, can promote phytoestrogens to enter the basal layer of the skin faster, can accelerate the metabolism of skin cells, and enable new cells to replace old cells containing melanin faster, thus achieving the whitening effect. In contrast, the phytoestrogens in Comparative Examples 1-6 cannot enter the deep layer of the skin and cannot provide long-lasting skin care effects on the skin surface, resulting in a decline in whitening performance.

[0071] 4. Skin Elasticity Test

[0072] Volunteers were randomly assigned to 17 different groups, with 5 members in each group. The test required each volunteer to use the skin care lotion once in the morning and once in the evening every day. On the 0th day, 21st day, and 35th day, a Cutometer skin elasticity tester produced by Courage & Khazaka of Germany was used to measure skin elasticity. The cheek area was selected as the test point, and the measurement was repeated five times in the same test area to obtain the average value. Among them, the skin elasticity growth rate W% = 100% * (NT - N0) / N0; N0 - the elastic test value on the 0th day; NT - the elastic test value during the Tth day period. The specific skin elasticity test results are shown in Table 6 below.

[0073] Table 6: Skin Elasticity Test Results

[0074]

[0075] According to the test results in Table 6, after using the skin care product lotion of the present invention for three weeks, the skin elasticity growth rate is greater than 12%, and after continuous use for five weeks, the skin elasticity growth rate exceeds 26%, endowing the skin with good elasticity. By comparing Examples 2, 5-8, it can be seen that the influence of the PEG molecular weight in DSPE-PEG-COOH on skin elasticity shows a trend of first increasing and then decreasing. Although low molecular weight DSPE-PEG-COOH can promote the rapid penetration of phytoestrogens to stimulate collagen synthesis and improve skin elasticity, the formed protective film is relatively thin, and the auxiliary effects such as moisturizing and antioxidant are limited, making it difficult to maintain long-term elasticity; the high molecular weight one forms a thick protective film, simulating the skin elastic structure to improve the appearance elasticity, but the permeability decreases, affecting the absorption and utilization of phytoestrogens.

[0076] In Comparative Examples 1-6, phospholipid polyethylene glycol carboxyl, limonene, or menthone was omitted or their ratios were changed, resulting in a poorer permeability of phytoestrogens on the skin surface and difficulty in penetrating the skin barrier to be effectively transported to the deep layer of the skin. As a result, the absorption and utilization efficiency of phytoestrogens decreased, leading to a significant reduction in skin elasticity. In Comparative Example 8, the biosurfactant was omitted, resulting in poor dispersion of phytoestrogens in the skin care lotion and a decrease in the content entering the deep layer of the skin, thereby causing a decrease in skin elasticity. In Comparative Example 7, the polypeptide was omitted and the skin elasticity also decreased.

[0077] 5. Evaluation of usage experience

[0078] To evaluate the experience of the product, a questionnaire survey was conducted on healthy female volunteers aged 35-55 after use. Each group was scored 5 points, and the usage experience was rated on a 10-point scale. Each group of volunteers used the lotions of the examples and comparative examples respectively, continuously for 30 days, once in the morning and once in the evening every day. The volunteers recorded whether there were any discomfort symptoms such as itching, burning, or persistent skin redness. The specific results are shown in Table 7 below:

[0079] Table 7: Test results of experience evaluation

[0080]

[0081] The test results in Table 7 show that the volunteers of Examples 1-9 did not experience any discomfort or allergic reactions such as itching, burning, or persistent skin redness during use. At the same time, they generally reported that the product was mild and comfortable, with a long-lasting moisturizing effect, and could effectively brighten the skin tone and remove freckles, and the overall usage experience was very good. In contrast, the users of the product in Comparative Example 2 reported the appearance of slight erythema, which may be due to the too high concentration of menthone, causing irritation to the skin. The users of the product in Comparative Example 7 reported that its moisturizing and skin-nourishing performance was poor, and the skin felt slightly tight after use, which may be due to the omission of the polypeptide component, resulting in the expansion of the stratum corneum under the long-term action of limonene and menthone, but the skin barrier could not be repaired in time.

[0082] The above examples are only examples provided to illustrate the present invention and are not limitations on the possible implementation modes of the present invention. Based on the content disclosed in the present invention, those skilled in the relevant art can make various forms of modifications and adjustments. It is impossible and unnecessary to list all possible implementation modes. Any modification, equivalent substitution, or improvement made within the basic principles and scope of the present invention shall be regarded as belonging to the protection scope of the present invention.

Claims

1. A moisturizing and whitening composition that promotes penetration and absorption, characterized in that: The raw materials include the following parts by weight: 1-15 parts of a permeation enhancer, 5-10 parts of phytoestrogen powder, 1-5 parts of a polypeptide, and 1-8 parts of a biosurfactant; The penetration enhancer is phospholipid polyethylene glycol carboxyl, limonene, and menthone, wherein the mass ratio of phospholipid polyethylene glycol carboxyl, limonene, and menthone is 5-10:1-5:0.5-1; The polypeptide is at least one of acetyl hexapeptide-8, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7; The molecular weight of polyethylene glycol in the phospholipid polyethylene glycol carboxyl group is 300-3000; The phytoestrogen powder is at least one of red clover extract, soybean stem extract, flaxseed extract and kudzu root extract.

2. The moisturizing and whitening composition for promoting penetration and absorption according to claim 1, characterized in that: The molecular weight of the polyethylene glycol in the phospholipid polyethylene glycol carboxyl group is 750-2000.

3. The moisturizing and whitening composition for promoting penetration and absorption according to claim 1, characterized in that: The phytoestrogen powder is a combination of red clover extract, soybean stem extract, flaxseed extract and kudzu root extract in a mass ratio of 1:2-3:1-3:0.5-1.

4. The moisturizing and whitening composition for promoting penetration and absorption according to claim 1, characterized in that: The biosurfactant is at least one of sodium cocoyl glutamate, lecithin, cocoyl glucoside, cocamidopropyl betaine, and cocamidopropyl hydroxybetaine.

5. Use of the moisturizing and whitening composition for promoting penetration and absorption as claimed in any one of claims 1 to 4 in skin care products, characterized in that: The dosage form of the skin care product includes any one of cream, emulsion, lotion, facial mask or lotion.

6. A skin care product with moisturizing and whitening properties, characterized in that: The skin care product contains 1-50wt% of the moisturizing and whitening composition for promoting penetration and absorption according to any one of claims 1-4.

7. The skin care product with moisturizing and whitening properties according to claim 6, characterized in that: The skin care product further comprises 1-15wt% moisturizing agent, 3-8wt% soothing agent, 0.5-2wt% emollient, 0.5-2wt% thickening agent, 0.1-2wt% pH adjusting agent, 0.1-1.5wt% antibacterial agent and the balance is water.

8. The skin care product with moisturizing and whitening properties according to claim 7, characterized in that: The moisturizer is selected from at least one of butylene glycol, glycerin, dipropylene glycol, sodium hyaluronate and niacinamide; the soothing agent is selected from at least one of sialic acid, mannitol, trehalose and ascorbic acid; the emollient is selected from at least one of polydimethylsiloxane, polydimethylsiloxane alcohol, hydrogenated polyisobutene, cyclopentasiloxane and isononyl isononanoate; the thickener is selected from at least one of xanthan gum, carbomer, sodium polyacrylate or hydroxyethyl cellulose; the pH adjuster is selected from at least one of triethanolamine, sodium citrate and disodium hydrogen phosphate; the antibacterial agent is selected from at least one of phenoxyethanol and parahydroxyacetophenone.

9. A method for preparing a skin care product with moisturizing and whitening properties as claimed in any one of claims 6 to 8, characterized in that: The following steps are involved: The components are uniformly mixed in deionized water under stirring conditions to obtain a moisturizing and whitening skin care product.

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