Sample analysis device and sample analysis method

Abstract

According to the sample analysis device and the sample analysis method, a target item applied by a to-be-tested sample is obtained, information of the to-be-tested sample is obtained, and when the target item is a first type of item, the to-be-tested sample is analyzed according to the information of the to-be-tested sample; and selecting one of at least the first sample suction mode and the second sample suction mode as the sample suction mode of the to-be-tested sample during the first type of items. According to the invention, two sample suction modes are provided for the first type of items, and one of the sample suction modes is selected as the sample suction mode for the first type of items based on the information of the sample to be detected, so that a better balance can be obtained between the sample suction stroke of the sample needle and the influence of factors such as erythrocyte sedimentation on sample suction and detection results.

Description

Technical Field

[0001] The present invention relates to the field of in vitro diagnosis, and particularly to a sample analysis device and a sample analysis method. Background Art

[0002] Generally, a sample analysis device forms a reaction solution by aspirating a sample to be tested and a reagent, and then detects the reaction solution to obtain the test result of the item of the sample to be tested. The step of aspirating the sample, or more generally, the step of processing the sample, has an important impact on the detection process and the detection result, etc. Taking the detection item of glycated hemoglobin as an example, its detection process and detection result, etc. are strongly related to the sample processing step.

[0003] In some solutions, the whole blood sample is first centrifuged, and then the device aspirates the sample at the bottom of the sample container (such as a sample tube) for detection. The reason for this is that after the whole blood sample is centrifuged, the plasma and red blood cells are separated, the density of the red blood cells at the bottom layer is higher, and the lighter interfering substances (such as blood lipids, etc.) are concentrated in the upper plasma; in this solution, the detection signal amplitude is large, the stability of the system is better, and it is less affected by erythrocyte sedimentation rate.

[0004] In some solutions, the whole blood sample is not centrifuged, but directly loaded onto the machine for detection, and the device also aspirates the sample at the bottom of the sample tube for detection. The reason for this is that since the sample does not need to be centrifuged, it is avoided that the parameters are incorrect due to centrifugation (such as causing too dense sedimentation of red blood cells), which may lead to inaccurate detection results; in addition, since the sample does not need to be centrifuged, the work efficiency can be improved.

[0005] The above solutions still have some problems. For example, since the device needs to aspirate the sample at the bottom of the sample tube, the travel of the sample needle in the sample tube is too long, which imposes more burden on the outer wall cleaning of the sample needle, making the cleaning process more complex and time-consuming; at the same time, the long travel of the sample needle needs to pass through the entire plasma layer, which is very likely to encounter foreign objects such as blood streaks, resulting in needle clogging. Summary of the Invention

[0006] Considering the above problems, the present invention provides a sample analysis device and a sample analysis method, which are specifically described below.

[0007] According to a first aspect, in one embodiment, a sample analysis device is provided, including: a dispensing component, a reagent component, a reaction component, a detection component, and a controller;

[0008] The dispensing component includes a sample needle, and the sample needle is used to aspirate a sample to be tested from a sample container containing the sample and dispense it to the reaction component;

[0009] The reagent component is used to provide a reagent to the reaction component;

[0010] The reaction component is used to form a reaction solution based on the sample to be tested and the reagent;

[0011] The detection component is used to detect the reaction solution to obtain a detection result of a target item;

[0012] The controller is used to, when the target item is a first - type item, select one of at least a first sampling mode and a second sampling mode as the sampling mode of the sample to be tested when performing the first - type item according to the information of the sample to be tested. In the first sampling mode: the sample needle extends into the sample container and aspirates the sample to be tested at a first height. In the second sampling mode: the sample needle extends into the sample container and aspirates the sample to be tested at a second height, where the first height is greater than the second height, and the sample to be tested corresponding to the first - type item is a whole - blood sample.

[0013] In one embodiment, the information of the sample to be tested is used to characterize the erythrocyte sedimentation rate of the sample to be tested. When the sample to be tested selects the first sampling mode, the erythrocyte sedimentation rate characterized by the information of the sample to be tested is less than the erythrocyte sedimentation rate characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode.

[0014] In one embodiment, the information of the sample to be tested includes at least one of the following: the medical history information of the subject to whom the sample to be tested belongs, and the detection results of the second - type detection items (also referred to as second - type items) of the sample to be tested.

[0015] In one embodiment, when the medical history information indicates that the subject has a history of anemia or tuberculosis, the controller selects the second sampling mode according to the medical history information.

[0016] In one embodiment, the detection results of the second - type detection items of the sample to be tested include the blood routine erythroid detection results and / or the erythrocyte sedimentation rate detection results of the sample to be tested; the blood routine erythroid detection results include at least one of hemoglobin concentration, hematocrit, and erythrocyte aggregation index. Among them, the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte sedimentation rate characterized by the sample to be tested; the higher the hematocrit of the sample to be tested, the smaller the erythrocyte sedimentation rate characterized by the sample to be tested; the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte aggregation index characterized by the sample to be tested.

[0017] In one embodiment, the information of the sample to be tested is used to characterize the erythrocyte sedimentation degree of the sample to be tested. When the sample to be tested selects the first sampling mode, the erythrocyte sedimentation degree characterized by the information of the sample to be tested is lower than that when the sample to be tested selects the second sampling mode.

[0018] In one embodiment, the information of the sample to be tested includes the first image information of the sample to be tested.

[0019] In one embodiment, when the target item applied for by the sample to be tested is the first type of item, the controller sets the sample to be tested as an emergency sample.

[0020] In one embodiment, the first type of item includes at least one of glycated hemoglobin, glucose-6-phosphate dehydrogenase, and 6-phosphogluconate dehydrogenase.

[0021] In one embodiment, the controller further obtains the second image information of the sample to be tested. When it is determined according to the second image information of the sample to be tested that there is a risk of needle clogging during sampling, the controller controls the sample needle to stop sampling the sample to be tested and issues a prompt; when there is no risk of needle clogging, the controller controls the sample needle to aspirate the sample to be tested from the sample container containing the sample to be tested and dispense it to the reaction component.

[0022] In one embodiment, the whole blood sample is a whole blood sample after being mixed evenly.

[0023] In one embodiment, under the first sampling mode and the second sampling mode, the cleaning parameters of the sample needle are different.

[0024] In one embodiment, when the target item is the third type of item, the controller controls the dispensing component to aspirate the sample to be tested from the sample container containing the sample to be tested and dispense it to the reaction component by using the third sampling mode. The sample to be tested corresponding to the third type of item is a serum sample; the detection component includes a light source component and a light measurement component. The light source component is used to generate irradiation light to irradiate the reaction solution, and the light measurement component is used to detect the light signal corresponding to the transmitted light and / or scattered light formed after the irradiation light passes through the reaction solution, and obtain the detection result of the target item according to the light signal.

[0025] According to the second aspect, in one embodiment, a sample analysis device is provided, including: a dispensing component, a reagent component, a reaction component, a detection component, and a controller;

[0026] The dispensing component is used to aspirate the sample to be tested from the sample container containing the sample to be tested and dispense it to the reaction component; the sample container includes a first sample container and a second sample container, and the specification of the second sample container is smaller than that of the first sample container;

[0027] The reagent component is used to provide a reagent to the reaction component;

[0028] The reaction component is used to form a reaction solution based on the sample to be tested and the reagent;

[0029] The detection component is used to detect the reaction solution to obtain a detection result of a target item;

[0030] The controller is used to, when the target item is a first - type item, select one of at least a first sample - aspiration mode and a second sample - aspiration mode as the sample - aspiration mode of the sample to be tested when performing the first - type item according to the information of the sample to be tested. In the first sample - aspiration mode: the dispensing component aspirates the sample to be tested from the first sample container and dispenses it to the reaction component. In the second sample - aspiration mode: the dispensing component aspirates the sample to be tested from the first sample container and dispenses it to the second sample container, then aspirates the sample to be tested from the second sample container and dispenses it to the reaction component; the sample to be tested corresponding to the first - type item is a whole - blood sample.

[0031] In one embodiment, the information of the sample to be tested is used to characterize the erythrocyte sedimentation rate of the sample to be tested. When the sample to be tested selects the first sample - aspiration mode, the erythrocyte sedimentation rate characterized by the information of the sample to be tested is less than the erythrocyte sedimentation rate characterized by the information of the sample to be tested when the sample to be tested selects the second sample - aspiration mode.

[0032] In one embodiment, the information of the sample to be tested includes at least one of the following: the medical history information of the subject to whom the sample to be tested belongs, the detection results of the second - type detection items (also referred to as second - type items) of the sample to be tested.

[0033] In one embodiment, when the medical history information indicates that the subject has a history of anemia or tuberculosis, the controller selects the second sample - aspiration mode according to the medical history information.

[0034] In one embodiment, the detection results of the second - type detection items of the sample to be tested include the detection results of the routine blood test erythroid series of the sample to be tested and / or the erythrocyte sedimentation rate detection results of the sample to be tested; the detection results of the routine blood test erythroid series include at least one of hemoglobin concentration, hematocrit, and erythrocyte aggregation index. Among them, the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte sedimentation rate characterized by the sample to be tested; the higher the hematocrit of the sample to be tested, the smaller the erythrocyte sedimentation rate characterized by the sample to be tested; the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte aggregation index characterized by the sample to be tested.

[0035] In one embodiment, the information of the sample to be tested is used to characterize the erythrocyte sedimentation degree of the sample to be tested. When the sample to be tested selects the first sampling mode, the erythrocyte sedimentation degree characterized by the information of the sample to be tested is lower than that when the sample to be tested selects the second sampling mode.

[0036] In one embodiment, the information of the sample to be tested includes the first image information of the sample to be tested.

[0037] In one embodiment, when the target item applied for by the sample to be tested is the first type of item, the controller sets the sample to be tested as an emergency sample.

[0038] In one embodiment, the first type of item includes at least one of glycated hemoglobin, glucose-6-phosphate dehydrogenase, and 6-phosphogluconate dehydrogenase.

[0039] In one embodiment, the controller further acquires the second image information of the sample to be tested. When it is determined according to the second image information of the sample to be tested that there is a risk of needle clogging during sampling, the controller controls the sample needle to stop sampling the sample to be tested and issues a prompt; when there is no risk of needle clogging, the controller controls the sample needle to suck the sample to be tested from the sample container containing the sample to be tested and dispense it to the reaction component.

[0040] In one embodiment, the whole blood sample is a whole blood sample after being mixed evenly.

[0041] In one embodiment, when the target item is the third type of item, the controller controls the dispensing component to suck the sample to be tested from the sample container containing the sample to be tested, such as the first sample container, in the third sampling mode and dispense it to the reaction component. The sample to be tested corresponding to the third type of item is a serum sample; the detection component includes a light source component and a light measurement component. The light source component is used to generate irradiation light to irradiate the reaction solution, and the light measurement component is used to detect the light signal corresponding to the transmitted light and / or scattered light formed after the irradiation light passes through the reaction solution, and obtain the detection result of the target item according to the light signal.

[0042] In one embodiment, the dispensing component includes a sample needle. In the first sampling mode: the sample needle extends into the first sample container and sucks the sample at the first height; in the second sampling mode: the sample needle extends into the first sample container and sucks the sample to be tested at the first height, and the sample needle extends into the second sample container and sucks the sample to be tested at the first height.

[0043] According to the third aspect, an embodiment provides a sample analysis method, including:

[0044] Obtain the target project applied for by the sample to be tested;

[0045] Obtain the information of the sample to be tested;

[0046] When the target project is a first - type project, select one of at least a first sampling mode and a second sampling mode as the sampling mode of the sample to be tested when performing the first - type project according to the information of the sample to be tested. In the first sampling mode: control the sample needle to extend into the sample container and aspirate the sample to be tested at a first height. In the second sampling mode: control the sample needle to extend into the sample container and aspirate the sample to be tested at a second height, where the first height is greater than the second height, and the sample to be tested corresponding to the first - type project is a whole - blood sample.

[0047] In one embodiment, the information of the sample to be tested is used to characterize the erythrocyte sedimentation rate of the sample to be tested. When the sample to be tested selects the first sampling mode, the erythrocyte sedimentation rate characterized by the information of the sample to be tested is less than the erythrocyte sedimentation rate characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode.

[0048] In one embodiment, the information of the sample to be tested is used to characterize the degree of erythrocyte sedimentation of the sample to be tested. When the sample to be tested selects the first sampling mode, the degree of erythrocyte sedimentation characterized by the information of the sample to be tested is lower than the degree of erythrocyte sedimentation characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode.

[0049] In one embodiment, the information of the sample to be tested includes at least one of the following: the medical history information of the subject to whom the sample to be tested belongs, the test results of the second - type test items of the sample to be tested.

[0050] In one embodiment, when the medical history information indicates that the subject has a history of anemia or tuberculosis, the controller selects the second sampling mode according to the medical history information.

[0051] In one embodiment, the test results of the second - type test items of the sample to be tested include the test results of the routine blood test erythroid series of the sample to be tested and / or the test results of the erythrocyte sedimentation rate of the sample to be tested; the test results of the routine blood test erythroid series include at least one of hemoglobin concentration, hematocrit, and erythrocyte aggregation index. Among them, the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte sedimentation rate characterized by the sample to be tested; the higher the hematocrit of the sample to be tested, the smaller the erythrocyte sedimentation rate characterized by the sample to be tested; the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte aggregation index characterized by the sample to be tested.

[0052] In one embodiment, the first type of items includes at least one of glycated hemoglobin, glucose-6-phosphate dehydrogenase, and 6-phosphogluconate dehydrogenase.

[0053] According to the fourth aspect, an embodiment provides a sample analysis method, including:

[0054] Obtaining a target item applied for by a sample to be tested;

[0055] Obtaining information of the sample to be tested;

[0056] When the target item is a first type of item, according to the information of the sample to be tested, selecting one of at least a first sampling mode and a second sampling mode as the sampling mode for the sample to be tested when performing the first type of item. In the first sampling mode: controlling to aspirate the sample to be tested from a first sample container and dispense it to a reaction component. In the second sampling mode: controlling a dispensing component to aspirate the sample to be tested from the first sample container and dispense it to a second sample container, and then aspirate the sample to be tested from the second sample container and dispense it to the reaction component; the specification of the second sample container is smaller than that of the first sample container, and the sample to be tested corresponding to the first type of item is a whole blood sample.

[0057] In one embodiment, the information of the sample to be tested is used to characterize the erythrocyte sedimentation rate of the sample to be tested. When the sample to be tested selects the first sampling mode, the erythrocyte sedimentation rate characterized by the information of the sample to be tested is less than the erythrocyte sedimentation rate characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode.

[0058] In one embodiment, the information of the sample to be tested is used to characterize the degree of erythrocyte sedimentation of the sample to be tested. When the sample to be tested selects the first sampling mode, the degree of erythrocyte sedimentation characterized by the information of the sample to be tested is lower than the degree of erythrocyte sedimentation characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode.

[0059] In one embodiment, the information of the sample to be tested includes at least one of the following: the medical history information of the subject to whom the sample to be tested belongs, the test results of the second type of test items (also referred to as the second type of items) of the sample to be tested.

[0060] In one embodiment, when the medical history information indicates that the subject has a history of anemia or tuberculosis, the controller selects the second sampling mode according to the medical history information.

[0061] In one embodiment, the test results of the second type of test items of the test sample include the blood routine erythroid test results of the test sample and / or the erythrocyte sedimentation rate test results of the test sample; the blood routine erythroid test results include at least one of hemoglobin concentration, hematocrit, and erythrocyte aggregation index. Among them, the higher the hemoglobin concentration of the test sample, the smaller the erythrocyte sedimentation rate of the test sample is characterized; the higher the hematocrit of the test sample, the smaller the erythrocyte sedimentation rate of the test sample is characterized; the higher the hemoglobin concentration of the test sample, the smaller the erythrocyte aggregation index of the test sample is characterized.

[0062] In one embodiment, the first type of items includes at least one of glycated hemoglobin, glucose-6-phosphate dehydrogenase, and 6-phosphogluconate dehydrogenase.

[0063] According to the sample analysis device and sample analysis method of the above embodiments, two sampling modes are provided for specific items (such as the first type of items), and one of the sampling modes is selected based on the information of the test sample as the sampling mode for performing the above specific items. This can achieve a better balance between the sampling stroke of the sample needle and factors such as erythrocyte sedimentation rate that affect sampling and test results. Description of the Drawings

[0064] Figure 1 It is a schematic structural diagram of a sample analysis device according to an embodiment;

[0065] Figure 2 It is a schematic structural diagram of a dispensing component according to an embodiment;

[0066] Figure 3 It is a schematic structural diagram of a sample analysis device according to an embodiment;

[0067] Figure 4 It is a schematic structural diagram of a sample analysis device according to an embodiment;

[0068] Figure 5 It is a schematic structural diagram of a sample analysis device according to an embodiment;

[0069] Figure 6 It is a schematic structural diagram of a sample analysis device according to an embodiment;

[0070] Figure 7 It is a schematic diagram of the first sampling mode and the second sampling mode in an embodiment;

[0071] Figure 8 It is a comparative schematic diagram of a first sample container and a second sample container in an embodiment;

[0072] Figure 9 It is a flowchart of a sample analysis method according to an embodiment;

[0073] Figure 10 It is a flowchart of a sample analysis method for an embodiment. Specific implementation manners

[0074] The present invention will be further described in detail below in conjunction with the accompanying drawings through specific implementation manners. Similar elements in different implementation manners adopt related similar element numbers. In the following implementation manners, many detailed descriptions are provided to enable a better understanding of the present application. However, those skilled in the art can easily recognize that some of the features can be omitted in different situations, or can be replaced by other elements, materials, or methods. In some cases, some operations related to the present application are not shown or described in the specification to avoid overwhelming the core part of the present application with excessive descriptions. For those skilled in the art, it is not necessary to describe these related operations in detail, and they can fully understand the related operations based on the descriptions in the specification and the general technical knowledge in the art.

[0075] In addition, the features, operations, or characteristics described in the specification can be combined in any appropriate manner to form various implementation manners. At the same time, the steps or actions in the method description can also be reordered or adjusted in a manner obvious to those skilled in the art. Therefore, the various sequences in the specification and the drawings are only for clearly describing a certain embodiment and do not mean that they are necessary sequences, unless it is stated that a certain sequence must be followed.

[0076] The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the described objects and do not have any sequential or technical meanings. And the "connection" and "coupling" mentioned in the present application, unless otherwise specified, both include direct and indirect connections (couplings).

[0077] The above describes the solutions of centrifuging the sample and then aspirating the sample at the bottom of the sample tube, as well as the solution of directly aspirating the sample at the bottom of the sample tube without centrifuging, and explains the advantages and disadvantages of these solutions; for the solution of directly aspirating the sample at the bottom of the sample tube, since it is not centrifuged, there are more interfering substances at the bottom of the sample tube than in the centrifuged sample, resulting in the problem of sample interference.

[0078] In some embodiments of the present application, the mixing treatment is replaced with the centrifuging treatment. By performing a mixing treatment on the whole blood sample, the red blood cells are more evenly distributed throughout the sample container (such as a sample tube). Therefore, the device can aspirate the sample from the upper part of the mixed whole blood sample for subsequent detection. This can make the travel of the sample needle in the sample container shorter. Therefore, it is easier to clean the outer wall of the sample needle, and the short travel of the sample needle also reduces the risk of needle blockage, etc.

[0079] In some embodiments of the present application, considering that factors such as a relatively high erythrocyte sedimentation rate may cause a decrease in the red blood cell density in the sample at the upper part of the sample container when the device aspirates the sample, thereby affecting the detection result, two sample aspiration modes are specifically proposed. For example, one sample aspiration mode is applicable to samples with a relatively high erythrocyte sedimentation rate, and the other sample aspiration mode is suitable for samples with a normal or even slow erythrocyte sedimentation rate.

[0080] First, a description will be given of the sample analysis device 100.

[0081] Please refer to Figure 1 , in some embodiments, the sample analysis device 100 includes a dispensing component 10, a reagent component 20, a reaction component 30, a detection component 40, and a controller 50. The following is a specific description.

[0082] The dispensing component 10 is used to aspirate a sample from the sample container 01 containing the sample to be tested and dispense it to the reaction component 30. In some embodiments, please refer to Figure 2 , the dispensing component 10 includes a sample needle 11. The sample needle 11 is used to aspirate the sample to be tested from the sample container 01 containing the sample to be tested and dispense it to the reaction component 30. In some embodiments, the dispensing component 10 may further include a driving mechanism 12 and a pressure source 13. The driving mechanism 12 is used to drive the sample needle 11 to move in space, such as two-dimensional or three-dimensional movement, so that the sample needle 11 can move above the sample container 01 and then descend into the sample container 01 to aspirate the sample to be tested, and the sample needle 11 can move to the reaction component 30 to dispense the sample to be tested; the pressure source 13 can provide corresponding pressures for the sample needle 11 to aspirate and dispense the sample to be tested.

[0083] The reagent component 20 is used to provide reagents to the reaction component 30. There are various implementation manners for the reagent component 20. For example, the reagent component 20 is connected to the reaction component 30 through a liquid path and provides reagents to the reaction component 30 through the liquid path; for another example, the reagent component 20 aspirates reagents from a reagent container through a reagent needle structure and provides them to the reaction component 30.

[0084] The reaction component 30 is used to form a reaction solution based on the sample to be tested and the reagent. The detection component 40 is used to detect the reaction solution to obtain the detection result of an item (such as a target item). In some embodiments, please refer to Figure 3 , the detection component 40 includes a light source assembly 41 and a light measurement assembly 42. The light source assembly 41 is used to generate irradiation light to irradiate the reaction solution, and the light measurement assembly 42 is used to detect the light signal corresponding to the transmitted light and / or scattered light formed after the irradiation light passes through the reaction solution, and obtain the detection result of the target item according to the light signal.

[0085] Please refer to Figure 4, in some embodiments, the sample analysis device 100 further includes a mixing component 60 for performing a mixing process. For example, the mixing component 60 mixes the reaction solution formed by the sample to be tested and the reagent; for another example, the mixing component 60 is used to mix the sample to be tested in the sample container 01 for the dispensing component 10 to aspirate the sample to be tested. The mixing component 60 can be implemented in various ways. For example, the mixing component 60 reuses the sample needle 11 and mixes the liquid by aspirating and discharging the sample needle 11 once or multiple times; for another example, the mixing component 60 includes a stirring rod structure and mixes the liquid in the container by stirring the stirring rod structure; for another example, the mixing component 60 includes an oscillation or shaking structure and oscillates or shakes the container through the oscillation or shaking structure to perform the mixing process; for another example, the mixing component 60 includes an ultrasonic generating structure and transmits ultrasonic waves to the liquid in the container through the ultrasonic generating structure to perform the mixing process.

[0086] Please refer to Figure 5 , in some embodiments, the sample container 01 has a label. Correspondingly, the sample analysis device 100 includes a label reader 91 for reading the information of the label. In some embodiments, the controller 50 obtains the information of the label through the label reader 91, and based on the information of the label, it can obtain what the target item applied for by the sample to be tested is. The label can be, for example, a barcode, and the label reader 91 can be, for example, a scanner.

[0087] Please refer to Figure 6 , in some embodiments, the sample analysis device 100 further includes a camera 92 for taking images. For example, it takes an image of the sample container 01 carrying the sample to be tested to obtain the image information of the sample to be tested; the timing of taking the image can be, for example, before aspirating the sample to be tested.

[0088] In some embodiments, the controller 50 obtains the image information of the sample to be tested - which may be referred to as the second image information. When it is determined according to the second image information of the sample to be tested that there is a risk of needle clogging during aspiration, the controller 50 controls the sample needle 11 to stop aspirating the sample to be tested and issues a prompt; in some embodiments, when there is no risk of needle clogging, the controller 50 controls the sample needle 11 to aspirate the sample to be tested from the sample container containing the sample to be tested and dispense it to the reaction component 30

[0089] There are various ways for the controller 50 to determine whether there is a risk of needle clogging based on the second image information of the sample to be tested. It can be through traditional image recognition methods or through methods such as machine learning. Existing or future proposed solutions can be adopted. This application does not make any limitations in this regard.

[0090] The sample analysis device 100 of some embodiments further has an emergency function, which means that emergency samples are preferentially tested (such as preferentially aspirated) relative to non-emergency samples. There are various ways to achieve preferential testing or so-called cutting in line testing, and existing or future solutions can be adopted. This application does not limit this.

[0091] In some embodiments, by default, the sample to be tested is a non-emergency sample. After the sample to be tested is set as an emergency sample, the controller 50 will then control to preferentially test the sample to be tested.

[0092] The above are some descriptions of the sample analysis device 100. In some embodiments, the sample analysis device 100 of this application can test whole blood samples, that is, the sample to be tested carried in the sample container 01 can be a whole blood sample. In some embodiments, the sample analysis device 100 of this application can test serum samples, that is, the sample to be tested carried in the sample container 01 can be a serum sample.

[0093] In some embodiments, the sample analysis device 100 can be an ion exchange chromatograph, an affinity chromatography instrument, an electrophoresis instrument or a biochemical analyzer.

[0094] In some embodiments, the sample analysis device 100 of this application has at least two sample aspiration modes, or it can also be said that the dispensing component 10 has at least two sample aspiration modes. For example, the first sample aspiration mode and the second sample aspiration mode, and for another example, the first sample aspiration mode, the second sample aspiration mode and the third sample aspiration mode. The following will be specifically described.

[0095] In some embodiments, in the first sample aspiration mode, the sample needle 11 extends into the sample container 01 and aspirates the sample at a first height; in some embodiments, in the second sample aspiration mode: the sample needle 11 extends into the sample container 01 and aspirates the sample at a second height, and the first height is greater than the second height.

[0096] In some embodiments, the sample to be tested is a whole blood sample and needs to be tested for target items; the controller 50 is used to select one of at least the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode when the sample to be tested is performing the target item according to the information of the sample to be tested; wherein, in the first sample aspiration mode: the sample needle 11 extends into the sample container 01 and aspirates the sample to be tested at a first height, and in the second sample aspiration mode: the sample needle 11 extends into the sample container 01 and aspirates the sample to be tested at a second height, and the first height is greater than the second height.

[0097] In some embodiments, when the target item is a first - type item, the controller 50 is configured to select, according to the information of the sample to be tested, one of at least a first sampling mode and a second sampling mode as the sampling mode for the sample to be tested when performing the first - type item. Wherein, in the first sampling mode: the sample needle 11 extends into the sample container 01 and aspirates the sample to be tested at a first height; in the second sampling mode: the sample needle 11 extends into the sample container 01 and aspirates the sample to be tested at a second height, and the first height is greater than the second height. In some embodiments, the sample to be tested corresponding to the first - type item is a whole - blood sample.

[0098] In some embodiments, the whole - blood sample is a whole - blood sample after mixing treatment. It can be that the user uses other devices to mix the whole - blood sample placed in the sample container 01, and then places the mixed whole - blood sample in the sample analysis device 100 for the sample needle 11 to aspirate the sample; or it can be that the user places the sample container 01 carrying the whole - blood sample in the sample analysis device 100, and the sample analysis device 100 mixes the whole - blood sample in the sample container 01 through the mixing component 60 for the sample needle 11 to aspirate the sample.

[0099] In some embodiments, the first sampling mode and the second sampling mode are for the same type of sample container 01, for example, with the same specifications, which is reflected in that the capacity, shape, etc. of the sample container 01 are all the same. In one example, this same - type sample container 01 can be the first sample container 01a mentioned in this article.

[0100] Therefore, for the same type of sample container 01, in the second sample - aspirating mode, the sample needle 11 needs to be deeper into the sample container 01 than in the first sampling mode. In the second sample - aspirating mode, the sample needle 11 descends a greater height and a greater distance. Figure 7 FIG. is a schematic diagram of two sampling modes, where the left side is an example of the first sampling mode and the right side is an example of the second sampling mode. H1 represents the first height and H2 represents the second height.

[0101] Therefore, in some embodiments, the first sampling mode can be used to aspirate the sample in the upper half of the sample container 01 - this can be achieved by setting the specific value of the first height, and the second sampling mode can be used to aspirate the sample in the lower half of the sample container 01 - this can be achieved by setting the specific value of the second height.

[0102] The above are some descriptions of the first sampling mode and the second sampling mode. One difference between the first sampling mode and the second sampling mode is the different sampling heights of the sample needle 11.

[0103] In some embodiments, the cleaning parameters of the sample needle 11 are different in the first sampling mode and the second sampling mode. Since the sampling heights of the sample needle 11 in the first sampling mode and the second sampling mode are different, that is, the parts of the needle body of the sample needle 11 contacting the sample to be tested are different. The part of the sample needle 11 in the second sampling mode contacting the sample to be tested not only includes the part of the sample needle 11 in the first sampling mode contacting the sample to be tested, but also has other parts contacting the sample to be tested. Therefore, different cleaning parameters are adopted for the two to ensure that there is no contamination caused by carrying the sample when the sample needle 11 performs the next sampling.

[0104] In some embodiments, the sample to be tested is a serum sample, which needs to be tested for target items; the controller 50 controls the dispensing component 10 to aspirate the sample to be tested from the sample container 01 containing the sample to be tested and dispense it to the reaction component 30 in the third sampling mode.

[0105] In some embodiments, when the target item is a third type of item, the controller 50 controls the dispensing component 10 to aspirate the sample to be tested from the sample container 01 containing the sample to be tested and dispense it to the reaction component 30 in the third sampling mode; in some embodiments, the sample to be tested corresponding to the third type of item is a serum sample. In some embodiments, the third type of item is different from the first type of item and the third type of item is a biochemical item.

[0106] In some embodiments, in the third sampling mode: the sample needle 11 extends into the sample container 01 and aspirates the sample to be tested at the fourth height.

[0107] In some embodiments, the fourth height is different from both the first height and the second height.

[0108] In some embodiments, the fourth height is the same as the first height - in such an example, the third sampling mode can also be combined into the first sampling mode, that is, it is considered that the third sampling mode is essentially the first sampling mode. In some embodiments, the fourth height is greater than the first height. In some embodiments, the fourth height is between the first height and the second height, that is, the fourth height is less than the first height and greater than the second height.

[0109] In some embodiments, the first sampling mode, the second sampling mode, and the third sampling mode are all for the same type of sample container 01, for example, with the same specifications, which is reflected in that the capacity, shape, etc. of the sample container 01 are all the same; in one example, this same type of sample container 01 can be the first sample container 01a mentioned below.

[0110] In some embodiments, different sampling modes can also be different sampling processes, which will be specifically described below.

[0111] In some embodiments, the sample container 01 includes two types of sample containers: a first sample container 01a and a second sample container 01b; that is, the first sample container 01a and the second sample container 01b are two different types of sample containers, and the specification of the second sample container 01b is smaller than that of the first sample container 01a. The specification of the second sample container 01b being smaller than that of the first sample container 01a allows, with the end faces of the open ends of both as a reference, when the sample needle 11 extends downward by the same distance, the distance from the lower end of the sample needle 11 to the bottom of the second sample container 01b to be less than the distance from the lower end of the sample needle 11 to the bottom of the first sample container 01a. In some embodiments, the specification refers to the capacity of the sample container; this can be reflected in the sample container as different lengths of the sample container; Figure 8 are examples of the first sample container 01a and the second sample container 01b. The first sample container 01a is longer than the second sample container 01b. For example, the first sample container 01a can be a sample tube of a normal specification or a long sample tube, and the second sample container 01b is a sample tube of a small specification or a short sample tube.

[0112] In some embodiments, in the first sample aspiration mode: the dispensing component 10 aspirates a sample from the first sample container 01a and dispenses it to the reaction component 30. In the second sample aspiration mode: the dispensing component 10 aspirates a sample from the first sample container 01a and dispenses it to the second sample container 01b, and then aspirates a sample from the second sample container 01b and dispenses it to the reaction component 30. That is, the difference between the first sample aspiration mode and the second sample aspiration mode lies in whether a transfer operation using the second sample container 01b is required.

[0113] In some embodiments, the sample to be tested is a whole blood sample, which needs to be tested for target items; the controller 50 selects one of at least the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target items according to the information of the sample to be tested; wherein, in the first sample aspiration mode: the dispensing component 10 aspirates the sample to be tested from the first sample container 01a and dispenses it to the reaction component 30. In the second sample aspiration mode: the dispensing component 10 aspirates the sample to be tested from the first sample container 01a and dispenses it to the second sample container 01b, and then aspirates the sample to be tested from the second sample container 01b and dispenses it to the reaction component 30.

[0114] In some embodiments, when the target item is a first - type item, the controller 50 is configured to select, according to the information of the sample to be tested, one of at least a first sample - aspiration mode and a second sample - aspiration mode as the sample - aspiration mode for the sample to be tested when performing the first - type item; wherein, in the first sample - aspiration mode: the dispensing component 10 aspirates the sample to be tested from the first sample container 01a and dispenses it to the reaction component 30; in the second sample - aspiration mode: the dispensing component 10 aspirates the sample to be tested from the first sample container 01a and dispenses it to the second sample container 01b, and then aspirates the sample to be tested from the second sample container 01b and dispenses it to the reaction component 30; in some embodiments, the sample to be tested corresponding to the first - type item is a whole - blood sample.

[0115] It can be seen that in the first sample - aspiration mode, after the dispensing component 10 aspirates the sample to be tested from the first sample container 01a, it directly dispenses it to the reaction component 30 without passing through the second sample container 01b; while in the second sample - aspiration mode, the dispensing component 30 aspirates the sample to be tested from the first sample container 01a and dispenses it to the second sample container 01b, and then the dispensing component 30 aspirates the sample to be tested from the second sample container 01b and dispenses it to the reaction component 30.

[0116] In some embodiments, for the sample to be tested determined to be in the second sample - aspiration mode, the controller 50 can first queue - jump the sample to be tested for priority sample aspiration, that is, first aspirate the sample to be tested from the first sample container 01a and dispense it to the second sample container 01b, and then, according to the normal test timing sequence and normal sample - aspiration order of the sample to be tested, arrange to aspirate the sample to be tested in the second sample container 01b. For example, if the sample to be tested has a first test timing sequence and a first priority level, when the sample to be tested is determined to be in the second sample - aspiration mode, the controller 50 can control the dispensing component 10 to aspirate the sample to be tested from the first sample container 01a and dispense it to the second sample container 01b in a priority order faster than the first test timing sequence and higher than the first priority level (such as the priority order of the emergency priority level); then, according to the first test timing sequence or the first priority level, control the dispensing component 10 to aspirate the sample to be tested from the second sample container 01b and dispense it to the reaction component 30.

[0117] In some embodiments, initially, the samples to be tested are all carried in the first sample container 01a.

[0118] In some embodiments, the whole blood sample is a whole blood sample after mixing treatment. It can be that the user uses other devices to mix the whole blood sample placed in the first sample container 01a, and then places the mixed whole blood sample in the sample analysis device 100 for the dispensing component 10 to aspirate the sample; it can also be that the user places the first sample container 01a carrying the whole blood sample in the sample analysis device 100, and the sample analysis device 100 mixes the whole blood sample in the first sample container 01a through the mixing component 60 for the dispensing component 10 to aspirate the sample.

[0119] In some embodiments, in the first sampling mode: the sampling needle 11 extends into the first sample container 01a and aspirates the sample at the first height; in the second sampling mode: the sampling needle 11 extends into the first sample container 01a and aspirates the sample to be tested at the first height, and the sampling needle 11 extends into the second sample container 01b and aspirates the sample to be tested at the third height.

[0120] In some embodiments, the difference between the third height and the first height is less than the threshold.

[0121] In some embodiments, the third height is approximately equal to the first height.

[0122] In some embodiments, the third height is equal to the first height, that is, in the second sampling mode: the sampling needle 11 extends into the first sample container 01a and aspirates the sample to be tested at the first height, and the sampling needle 11 extends into the second sample container 01b and aspirates the sample to be tested at the first height.

[0123] In some embodiments, the first sampling mode can be used to aspirate the sample in the upper half of the sample container 01a - this can be achieved by setting the specific value of the first height.

[0124] In some embodiments, the second sampling mode can be used to aspirate the sample in the upper half of the sample container 01a - this can be achieved by setting the specific value of the first height.

[0125] In one embodiment, for the two cases of the sampling needle 11 extending into the first sample container 01a to aspirate the sample and the sampling needle 11 extending into the second sample container 01b to aspirate the sample, the end faces of the open ends of the first sample container 01a and the second sample container 01b are at the same height.

[0126] The above are some descriptions of the first sampling mode and the second sampling mode. One difference between the first sampling mode and the second sampling mode is that the second sampling mode also borrows another type of sample container.

[0127] In some embodiments, the sample to be tested is a serum sample, which needs to be tested for target items; the controller 50 controls the dispensing component 10 to aspirate the sample to be tested from a sample container 01 containing the sample to be tested, such as the first sample container 01a, in the third sample aspiration mode and dispense it to the reaction component 30.

[0128] In some embodiments, when the target item is a third - type item, the controller 50 controls the dispensing component 10 to aspirate the sample to be tested from a sample container 01 containing the sample to be tested, such as the first sample container 01a, in the third sample aspiration mode and dispense it to the reaction component 30; in some embodiments, the sample to be tested corresponding to the third - type item is a serum sample. In some embodiments, the third - type item is different from the first - type item and the third - type item is a biochemical item.

[0129] In some embodiments, in the third sample aspiration mode: the sample needle 11 extends into the first sample container 01a and aspirates the sample to be tested at a fifth height.

[0130] In some embodiments, the fifth height is different from the first height. In some embodiments, the fifth height is different from the third height.

[0131] In some embodiments, the fifth height is the same as the first height - in such an example, the third sample aspiration mode can also be combined into the first sample aspiration mode, that is, it is considered that the third sample aspiration mode is essentially the first sample aspiration mode.

[0132] In some embodiments, the fifth height is greater than the first height.

[0133] The following describes how to specifically select the sample aspiration mode.

[0134] As described above, when the target item is a first - type item or the sample to be tested is a whole - blood sample, the controller 50 selects one of at least the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item, such as the first - type item, according to the information of the sample to be tested.

[0135] In some embodiments, the first - type items include at least one of glycated hemoglobin, glucose - 6 - phosphate dehydrogenase, and 6 - phosphogluconate dehydrogenase.

[0136] In some embodiments, the information of the sample to be tested is used to characterize the erythrocyte sedimentation rate of the sample to be tested.

[0137] The erythrocyte sedimentation rate (ESR), also simply referred to as sedimentation rate, refers to the speed at which erythrocytes sediment under certain conditions. For example, when anticoagulated whole blood is placed statically in a vertically erected glass tube, due to the relatively large specific gravity of erythrocytes, they naturally sink under the action of gravity. Under normal circumstances, the sinking is very slow. Clinically, the sedimentation rate of erythrocytes is often represented by the distance that erythrocytes sink at the end of the first hour; generally speaking, the ESR values of ordinary people fluctuate within a relatively narrow range, while many pathological conditions can significantly increase the ESR. The erythrocyte sedimentation rate can be the result of the interaction of multiple factors.

[0138] In some embodiments, when the test sample selects the first sampling mode, the erythrocyte sedimentation rate characterized by the information of the test sample is less than the erythrocyte sedimentation rate characterized by the information of the test sample when the test sample selects the second sampling mode.

[0139] In some embodiments, the information of the test sample includes at least one of the following: the medical history information of the subject to whom the test sample belongs, the test results of the second type of test items (also referred to as the second type of items) of the test sample, and the first image information of the test sample.

[0140] In some embodiments, when the medical history information indicates that the subject has a medical history of anemia or tuberculosis, the controller 50 selects the second sampling mode according to the medical history information. Generally speaking, if the subject has a medical history of anemia or tuberculosis, their erythrocyte sedimentation rate will be larger than that of a normal test sample.

[0141] In some embodiments, the medical history information can be manually input by the user into the sample analysis device 100 through an input tool such as a keyboard, so that the controller 50 can obtain the medical history information of the subject to whom the test sample belongs.

[0142] In some embodiments, the controller 50 can obtain the medical history information of the subject to whom the test sample belongs based on other systems that register the test sample, such as the medical history information.

[0143] In some embodiments, after the controller 50 obtains the information of the label through the label reader 91, it can obtain the medical history information of the subject to whom the test sample belongs based on the information of the label.

[0144] In some embodiments, the test results of the second type of test items of the sample to be tested include the blood routine erythroid test results of the sample to be tested and / or the erythrocyte sedimentation rate test results of the sample to be tested. In some embodiments, the blood routine erythroid test results include at least one of hemoglobin concentration, hematocrit, and erythrocyte aggregation index. Among them, the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte sedimentation rate of the sample to be tested is characterized; the higher the hematocrit of the sample to be tested, the smaller the erythrocyte sedimentation rate of the sample to be tested is characterized; the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte aggregation index of the sample to be tested is characterized.

[0145] In some embodiments, when the hemoglobin concentration of the sample to be tested is less than the first value, the controller 50 selects the second sampling mode according to the detection result of the hemoglobin concentration; otherwise, it selects the first sampling mode.

[0146] In some embodiments, when the hematocrit of the sample to be tested is less than the second value, the controller 50 selects the second sampling mode according to the detection result of the hematocrit; otherwise, it selects the first sampling mode.

[0147] In some embodiments, when the erythrocyte aggregation index of the sample to be tested is less than the third value, the controller 50 selects the second sampling mode according to the detection result of the erythrocyte aggregation index; otherwise, it selects the first sampling mode.

[0148] In some embodiments, the erythrocyte sedimentation rate test results include direct erythrocyte sedimentation rate results and / or indirect erythrocyte sedimentation rate results.

[0149] In some embodiments, when the erythrocyte sedimentation rate test result of the sample to be tested is greater than the fourth value, the controller 50 selects the second sampling mode according to the detection result of the erythrocyte sedimentation rate test result; otherwise, it selects the first sampling mode.

[0150] In some embodiments, the controller 50 can obtain the test results of the second type of test items of the sample to be tested through, such as, the LIS system. The LIS system (Laboratory Information System) is the laboratory (clinical laboratory) information system, which is one of the important components of hospital information management.

[0151] In some embodiments, the sample analysis device 100 itself can perform the second type of test items. Therefore, the controller 50 can obtain the test results based on the second type of test items performed on the sample to be tested on the machine. For example, the controller 50 can control the sample to be tested to first perform the second type of test items, and then perform the first type of test items after the test results come out. In some embodiments, the second type of test items can be the same test items as the third type of items mentioned in this article, or the two include some of the same test items.

[0152] In some embodiments, the information of the sample to be tested is used to characterize the erythrocyte sedimentation degree of the sample to be tested.

[0153] The erythrocyte sedimentation degree is used to characterize the situation of the erythrocyte sedimentation of the sample to be tested in the current actual or expected situation. Under the same time, the lower the erythrocyte sedimentation degree, generally speaking, the smaller its erythrocyte sedimentation rate.

[0154] In some embodiments, when the sample to be tested selects the first sampling mode, the erythrocyte sedimentation degree characterized by the information of the sample to be tested is lower than that when the sample to be tested selects the second sampling mode.

[0155] In some embodiments, the information of the sample to be tested includes at least one of the following: the medical history information of the subject to whom the sample to be tested belongs, the test results of the second type of test items (also referred to as the second type of items) of the sample to be tested, and the first image information of the sample to be tested.

[0156] In some embodiments, when the medical history information indicates that the subject has a medical history of anemia or tuberculosis, the controller 50 selects the second sampling mode according to the medical history information. Generally speaking, when the subject has a medical history of anemia or tuberculosis, the actual or expected erythrocyte sedimentation degree during sampling will be relatively high and large.

[0157] For the acquisition of the medical history information, reference can be made to the above text, which will not be elaborated here.

[0158] In some embodiments, the test results of the second type of test items of the sample to be tested include the test results of the routine blood test erythroid series of the sample to be tested and / or the test results of the erythrocyte sedimentation of the sample to be tested. In some embodiments, the test results of the routine blood test erythroid series include at least one of hemoglobin concentration, hematocrit, and erythrocyte aggregation index. Among them, the higher the hemoglobin concentration of the sample to be tested, the lower the current actual or expected erythrocyte sedimentation degree of the sample to be tested; the higher the hematocrit of the sample to be tested, the lower the current actual or expected erythrocyte sedimentation degree of the sample to be tested; the higher the hemoglobin concentration of the sample to be tested, the lower the current actual or expected erythrocyte sedimentation degree of the sample to be tested.

[0159] In some embodiments, when the hemoglobin concentration of the sample to be tested is less than the first value, the controller 50 selects the second sampling mode according to the test results of the hemoglobin concentration, and vice versa, selects the first sampling mode.

[0160] In some embodiments, when the hematocrit of the sample to be tested is less than the second value, the controller 50 selects the second sampling mode according to the test results of the hematocrit, and vice versa, selects the first sampling mode.

[0161] In some embodiments, when the erythrocyte aggregation index of the sample to be tested is less than a third value, the controller 50 selects the second sampling mode according to the detection result of the erythrocyte aggregation index; otherwise, the first sampling mode is selected.

[0162] In some embodiments, the erythrocyte sedimentation test result includes a direct erythrocyte sedimentation result and / or an indirect erythrocyte sedimentation result.

[0163] In some embodiments, when the erythrocyte sedimentation test result of the sample to be tested is greater than a fourth value, the controller 50 selects the second sampling mode according to the detection result of the erythrocyte sedimentation test result; otherwise, the first sampling mode is selected.

[0164] In some embodiments, the controller 50 can obtain the detection results of the second type of test items of the sample to be tested through, such as, a LIS system. The LIS system (Laboratory Information System) is the laboratory (clinical laboratory) information system, which is one of the important components of hospital information management.

[0165] In some embodiments, the sample analysis device 100 itself can perform the second type of test items. Therefore, the controller 50 can obtain the detection results based on the second type of test items performed on the sample to be tested by the device itself. For example, the controller 50 can control the sample to be tested to first perform the second type of test items, and then perform the first type of test items after the test results are obtained. In some embodiments, the second type of test items can be the same test items as the third type of items mentioned in this article, or the two include some identical test items.

[0166] In some embodiments, the first image information of the sample to be tested can characterize the erythrocyte sedimentation degree of the sample to be tested. In some embodiments, when it is determined according to the first image information of the sample to be tested that the erythrocyte sedimentation degree of the sample to be tested is low - for example, most of the erythrocytes are focused on the upper-middle part of the sample container, the controller 50 selects the first sampling mode according to the detection result of the erythrocyte sedimentation test result; otherwise, the second sampling mode is selected.

[0167] In some embodiments, the information of the sample to be tested includes the first image information of the sample to be tested. The controller 50 can select one of at least the first sampling mode and the second sampling mode as the sampling mode of the sample to be tested when performing a target item, such as the first type of item, based on the first image information of the sample to be tested.

[0168] In some embodiments, the shooting opportunity can be before sampling the sample to be tested, for example, before the controller 50 determines which sampling mode to use for the sample to be tested. The controller 50 can obtain the first image information of the sample to be tested through the camera 91 mentioned above.

[0169] In some embodiments, the first image information and the second image information of the sample to be tested are the image information obtained by the camera 92 taking a single shot of the sample to be tested.

[0170] The above are some descriptions for determining whether to use the first sampling mode or the second sampling mode as the sampling mode of the sample to be tested when performing a target item, such as a first type of item, based on the information of the sample to be tested.

[0171] By the information of the sample to be tested, the erythrocyte sedimentation rate or degree of the sample to be tested is judged, so as to determine whether to use the first sampling mode or the second sampling mode as the sampling mode of the sample to be tested when performing a target item, such as a first type of item. This can achieve a better balance between the sampling stroke of the sampling needle 11 and factors such as erythrocyte sedimentation rate that affect sampling and test results.

[0172] In some embodiments, when the target item applied for by the sample to be tested is a first type of item, the controller 50 sets the sample to be tested as an emergency sample, so as to preferentially test and sample the sample to be tested. This can further reduce the influence of factors such as erythrocyte sedimentation rate on sampling and test results.

[0173] Simple combination of emergency and two sampling modes can obtain more solutions. In some embodiments, when the target item applied for by the sample to be tested is a first type of item, the controller 50 sets the sample to be tested as an emergency sample, so as to preferentially test and sample the sample to be tested; when determining the sampling mode of the sample to be tested when performing a first type of item, the controller 50 selects one from at least the first sampling mode and the second sampling mode as the sampling mode of the sample to be tested when performing a first type of item according to the information of the sample to be tested. For example, when the information of the sample to be tested indicates a relatively high erythrocyte sedimentation rate or a relatively high degree of erythrocyte sedimentation, the controller 50 uses the second sampling mode as the sampling mode of the sample to be tested when performing a first type of item. On the contrary, the controller 50 uses the first sampling mode as the sampling mode of the sample to be tested when performing a first type of item.

[0174] In addition, in some embodiments, when the target item applied for by the sample to be tested is a first type of item, the controller 50 sets the sample to be tested as an emergency sample, so as to preferentially test and sample the sample to be tested; in this case, it can be determined that the sampling mode of the sample to be tested when performing a first type of item is uniformly the first sampling mode or uniformly the second sampling mode, rather than selecting one from at least the first sampling mode and the second sampling mode as the sampling mode of the sample to be tested when performing a first type of item according to the information of the sample to be tested.

[0175] In some embodiments, the controller 50 is capable of selecting one of a first sample aspiration mode, a second sample aspiration mode, and a third sample aspiration mode as the sample aspiration mode for the sample to be tested when performing a target item based on the sample type and the information of the sample to be tested. When the sample type is a whole blood sample, it indicates that the sample aspiration mode of the sample to be tested is the first sample aspiration mode or the second sample aspiration mode, and the controller 50 is capable of selecting one of the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the sample type is a serum sample, it indicates that the sample aspiration mode of the sample to be tested is the third sample aspiration mode, and thus the controller 50 selects the third sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item.

[0176] In some embodiments, the information of the sample to be tested can characterize the sample type; in such an example, the controller 50 can then select one of a first sample aspiration mode, a second sample aspiration mode, and a third sample aspiration mode as the sample aspiration mode for the sample to be tested when performing a target item based on the information of the sample to be tested.

[0177] In some embodiments, the controller 50 is capable of selecting one of a first sample aspiration mode, a second sample aspiration mode, and a third sample aspiration mode as the sample aspiration mode for the sample to be tested when performing a target item based on the target item to be performed on the sample to be tested and the information of the sample to be tested. When the target item to be performed on the sample to be tested is a first type of item, it indicates that the sample aspiration mode of the sample to be tested is the first sample aspiration mode or the second sample aspiration mode, and the controller 50 is capable of selecting one of the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the target item to be performed on the sample to be tested is a third type of item, it indicates that the sample aspiration mode of the sample to be tested is the third sample aspiration mode, and thus the controller 50 selects the third sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item.

[0178] In some embodiments, the information of the sample to be tested can characterize whether the target item to be performed on the sample to be tested is a first type of item or a third type of item; in such an example, the controller 50 can then select one of a first sample aspiration mode, a second sample aspiration mode, and a third sample aspiration mode as the sample aspiration mode for the sample to be tested when performing a target item based on the information of the sample to be tested.

[0179] In some embodiments, the controller 50 is capable of selecting one of a first sampling mode, a second sampling mode, and a third sampling mode as the sampling mode for the sample to be tested when performing the target item based on the sample type, the target item to be performed on the sample to be tested, and the information of the sample to be tested. When the sample type is a whole blood sample and the target item to be performed is a first type of item, it indicates that the sampling mode of the sample to be tested is the first sampling mode or the second sampling mode, and the controller 50 is capable of selecting one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the sample type is a serum sample and the target item to be performed is a third type of item, it indicates that the sampling mode of the sample to be tested is the third sampling mode, and thus the controller 50 selects the third sampling mode as the sampling mode for the sample to be tested when performing the target item.

[0180] In some embodiments, the information of the sample to be tested can characterize the sample type and / or whether the target item to be performed on the sample to be tested is a first type of item or a third type of item.

[0181] In some embodiments, the third sampling mode and the first sampling mode can be the same sampling mode.

[0182] Therefore, in some embodiments, the controller 50 is capable of selecting one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the sample type and the information of the sample to be tested. When the sample type is a whole blood sample, the controller 50 is capable of selecting one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the sample type is a serum sample, it indicates that the sampling mode of the sample to be tested is the first sampling mode, and thus the controller 50 selects the first sampling mode as the sampling mode for the sample to be tested when performing the target item.

[0183] In some embodiments, the information of the sample to be tested can characterize the sample type; in such an example, the controller 50 is then capable of selecting one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested.

[0184] In some embodiments, the controller 50 is capable of selecting one of a first sampling mode and a second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the target item to be performed on the sample to be tested and the information of the sample to be tested. When the target item to be performed on the sample to be tested is a first type of item, the controller 50 is capable of selecting one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the target item to be performed on the sample to be tested is a third type of item, it indicates that the sampling mode of the sample to be tested is a third sampling mode. Therefore, the controller 50 selects the third sampling mode as the sampling mode for the sample to be tested when performing the target item.

[0185] In some embodiments, the information of the sample to be tested can characterize whether the target item to be performed on the sample to be tested is a first type of item or a third type of item; in such an example, the controller 50 can then select one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested.

[0186] In some embodiments, the controller 50 is capable of selecting one of a first sampling mode and a second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the sample type, the target item to be performed on the sample to be tested, and the information of the sample to be tested. When the sample type is a whole blood sample and the target item to be performed is a first type of item, the controller 50 is capable of selecting one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the sample type is a serum sample and the target item to be performed is a third type of item, it indicates that the sampling mode of the sample to be tested is a third sampling mode. Therefore, the controller 50 selects the third sampling mode as the sampling mode for the sample to be tested when performing the target item.

[0187] In some embodiments, the information of the sample to be tested can characterize the sample type and / or whether the target item to be performed on the sample to be tested is a first type of item or a third type of item.

[0188] Some embodiments also disclose a sample analysis method, which can be applied to the sample analysis device 100 in some embodiments herein.

[0189] Please refer to Figure 9 , the sample analysis method of some embodiments includes the following steps:

[0190] Step 110: Obtain the target item applied for by the sample to be tested.

[0191] Step 120: Obtain the information of the sample to be tested.

[0192] In some embodiments, the information of the sample to be tested is used to characterize the erythrocyte sedimentation rate and / or the degree of erythrocyte sedimentation of the sample to be tested.

[0193] Step 130: Determine the sampling mode of the sample to be tested from at least a first sampling mode and a second sampling mode.

[0194] In some specific embodiments, when the target item is a first type of item, in step 130, according to the information of the sample to be tested, one of at least a first sampling mode and a second sampling mode is selected as the sampling mode of the sample to be tested when performing the first type of item; in the first sampling mode, the sample needle 11 extends into the sample container 01 and aspirates the sample at a first height; in some embodiments, in the second sampling mode: the sample needle 11 extends into the sample container 01 and aspirates the sample at a second height, and the first height is greater than the second height. In some embodiments, the sample to be tested corresponding to the first type of item is a whole blood sample.

[0195] In some embodiments, the first sampling mode and the second sampling mode are for the same type of sample container 01, for example, the specifications are the same, which is reflected in that the capacity, shape, etc. of the sample container 01 are all the same; in one example, this same type of sample container 01 can be the first sample container 01a mentioned in this article.

[0196] In some embodiments, the first sampling mode can be used to aspirate the sample to be tested in the upper half of the sample container 01 - this can be achieved by setting the specific value of the first height, and the second sampling mode can be used to aspirate the sample to be tested in the lower half of the sample container 01 - this can be achieved by setting the specific value of the second height.

[0197] In some embodiments, the whole blood sample is a whole blood sample after being mixed. It can be that the user uses other devices to mix the whole blood sample placed in the sample container 01, and then places the mixed whole blood sample in the sample analysis device 100 for the sample needle 11 to aspirate the sample; it can also be that the user places the sample container 01 carrying the whole blood sample in the sample analysis device 100, and the sample analysis device 100 mixes the whole blood sample in the sample container 01 through the mixing component 60 for the sample needle 11 to aspirate the sample.

[0198] The above are some descriptions of the first sampling mode and the second sampling mode, and one difference between the first sampling mode and the second sampling mode is that the sampling height of the sample needle 11 is different.

[0199] In some embodiments, when the target project is a third - type project in step 130, the controller 50 controls the dispensing component 10 to aspirate the sample to be tested from the sample container 01 containing the sample to be tested and dispense it to the reaction component 30 in the third sample aspiration mode; in some embodiments, the sample to be tested corresponding to the third - type project is a serum sample. The third - type project and the third sample aspiration mode can refer to some records above and will not be elaborated here.

[0200] In some embodiments, different sample aspiration modes can also be different sample aspiration processes, which will be specifically described below.

[0201] In some specific embodiments, when the target project is a first - type project in step 130, according to the information of the sample to be tested, one of at least the first sample aspiration mode and the second sample aspiration mode is selected as the sample aspiration mode for the sample to be tested when performing the first - type project; in the first sample aspiration mode: control the dispensing component 10 to aspirate the sample from the first sample container 01a and dispense it to the reaction component 30, in the second sample aspiration mode: control the dispensing component 10 to aspirate the sample from the first sample container 01a and dispense it to the second sample container 01b, and then aspirate the sample from the second sample container 01b and dispense it to the reaction component 30; the specification of the second sample container 01b is smaller than that of the first sample container 01a, and the sample to be tested corresponding to the first - type project is a whole - blood sample. Further descriptions of the first sample container 01a and the second sample container 01b can refer to the descriptions above and will not be elaborated here.

[0202] In some embodiments, in the first sample aspiration mode: the sample needle 11 extends into the first sample container 01a and aspirates the sample at the first height; in the second sample aspiration mode: the sample needle 11 extends into the first sample container 01a and aspirates the sample to be tested at the first height, and the sample needle 11 extends into the second sample container 01b and aspirates the sample to be tested at the third height.

[0203] In some embodiments, the difference between the third height and the first height is less than the threshold.

[0204] In some embodiments, the third height is approximately equal to the first height.

[0205] In some embodiments, the third height is equal to the first height, that is, in the second sample aspiration mode: the sample needle 11 extends into the first sample container 01a and aspirates the sample to be tested at the first height, and the sample needle 11 extends into the second sample container 01b and aspirates the sample to be tested at the first height.

[0206] In some embodiments, the first sample aspiration mode can be used to aspirate the upper - half part of the sample in the sample container 01a - this can be achieved by setting the specific value of the first height.

[0207] In some embodiments, in the second sample aspiration mode, it is possible to aspirate the sample in the upper half of the sample container 01a - this can be achieved by setting a specific value for the first height.

[0208] In one embodiment, for the two cases where the sample needle 11 extends into the first sample container 01a to aspirate the sample and the sample needle 11 extends into the second sample container 01b to aspirate the sample, the end faces of the open ends of the first sample container 01a and the second sample container 01b are at the same height.

[0209] In some embodiments, when the target item is a third - type item, the controller 50 controls the dispensing component 10 to aspirate the sample to be tested from the sample container 01 containing the sample to be tested, such as the first sample container 01a, in the third sample aspiration mode and dispense it to the reaction component 30; in some embodiments, the sample to be tested corresponding to the third - type item is a serum sample. In some embodiments, the third - type item is different from the first - type item and the third - type item is a biochemical item.

[0210] In some embodiments, in the third sample aspiration mode: the sample needle 11 extends into the first sample container 01a and aspirates the sample to be tested at the fifth height.

[0211] In some embodiments, the fifth height is different from the first height. In some embodiments, the fifth height is different from the third height.

[0212] In some embodiments, the fifth height is the same as the first height - in such an example, the third sample aspiration mode can also be combined into the first sample aspiration mode, that is, it is considered that the third sample aspiration mode is essentially the first sample aspiration mode.

[0213] In some embodiments, the fifth height is greater than the first height.

[0214] The above are some descriptions of different sample aspiration modes. One difference between the first sample aspiration mode and the second sample aspiration mode is that the second sample aspiration mode also borrows another type of sample container.

[0215] Next, an explanation will be given on how step 130 selects the sample aspiration mode based on the information of the sample to be tested.

[0216] As described above, when the target item is a first - type item or the sample to be tested is a whole - blood sample, step 130 selects one of at least the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item, such as the first - type item, according to the information of the sample to be tested.

[0217] In some embodiments, the first - type items include at least one of glycated hemoglobin, glucose - 6 - phosphate dehydrogenase, and 6 - phosphogluconate dehydrogenase.

[0218] In some embodiments, the information of the sample to be tested is used to characterize the erythrocyte sedimentation rate of the sample to be tested.

[0219] In some embodiments, when the sample to be tested selects the first sampling mode, the erythrocyte sedimentation rate characterized by the information of the sample to be tested is less than the erythrocyte sedimentation rate characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode.

[0220] In some embodiments, the information of the sample to be tested includes at least one of the following: the medical history information of the subject to whom the sample to be tested belongs, the test results of the second type of test items (also referred to as the second type of items) of the sample to be tested, and the first image information of the sample to be tested.

[0221] In some embodiments, when the medical history information indicates that the subject has a history of anemia or tuberculosis, step 130 selects the second sampling mode according to the medical history information. Generally speaking, if the subject has a history of anemia or tuberculosis, the erythrocyte sedimentation rate is larger than that of a normal sample to be tested.

[0222] In some embodiments, the medical history information can be manually input by the user into the sample analysis device 100 through an input tool such as a keyboard, so that step 130 can obtain the medical history information of the subject to whom the sample to be tested belongs.

[0223] In some embodiments, step 130 can obtain the medical history information of the subject to whom the sample to be tested belongs based on other systems that register the sample to be tested, such as the medical history information system.

[0224] In some embodiments, after step 130 obtains the information of the label through the label reader 91, it can obtain the medical history information of the subject to whom the sample to be tested belongs based on the information of the label.

[0225] In some embodiments, the test results of the second type of test items of the sample to be tested include the test results of the routine blood test erythroid series of the sample to be tested and / or the test results of the erythrocyte sedimentation rate of the sample to be tested. In some embodiments, the test results of the routine blood test erythroid series include at least one of hemoglobin concentration, hematocrit, and erythrocyte aggregation index. Among them, the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte sedimentation rate characterized by the sample to be tested; the higher the hematocrit of the sample to be tested, the smaller the erythrocyte sedimentation rate characterized by the sample to be tested; the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte aggregation index characterized by the sample to be tested.

[0226] In some embodiments, when the hemoglobin concentration of the sample to be tested is less than the first value, step 130 selects the second sampling mode according to the test results of the hemoglobin concentration, and vice versa, selects the first sampling mode.

[0227] In some embodiments, when the hematocrit of the sample to be tested is less than the second value, step 130 selects the second sampling mode according to the detection result of the hematocrit; otherwise, the first sampling mode is selected.

[0228] In some embodiments, when the erythrocyte aggregation index of the sample to be tested is less than the third value, step 130 selects the second sampling mode according to the detection result of the erythrocyte aggregation index; otherwise, the first sampling mode is selected.

[0229] In some embodiments, the erythrocyte sedimentation test result includes a direct erythrocyte sedimentation result and / or an indirect erythrocyte sedimentation result.

[0230] In some embodiments, when the erythrocyte sedimentation test result of the sample to be tested is greater than the fourth value, step 130 selects the second sampling mode according to the detection result of the erythrocyte sedimentation test result; otherwise, the first sampling mode is selected.

[0231] In some embodiments, step 130 can obtain the detection results of the second type of test items of the sample to be tested through, such as, an LIS system. The LIS system (Laboratory Information System) is the laboratory (clinical laboratory) information system and is one of the important components of hospital information management.

[0232] In some embodiments, the sample analysis device 100 itself can perform the second type of test items. Therefore, step 130 can obtain the detection results based on the second type of test items performed on the sample to be tested on the device itself. For example, step 130 can control the sample to be tested to first perform the second type of test items, and then perform the first type of test items after the test results are obtained. In some embodiments, the second type of test items can be the same test items as the third type of items mentioned in this article, or the two include some of the same test items.

[0233] In some embodiments, the information of the sample to be tested is used to characterize the degree of erythrocyte sedimentation of the sample to be tested.

[0234] In some embodiments, when the first sampling mode is selected for the sample to be tested, the degree of erythrocyte sedimentation characterized by the information of the sample to be tested is lower than that when the second sampling mode is selected for the sample to be tested.

[0235] In some embodiments, the information of the sample to be tested includes at least one of the following: the medical history information of the subject to whom the sample to be tested belongs, the detection results of the second type of test items (also referred to as the second type of items) of the sample to be tested, and the first image information of the sample to be tested.

[0236] In some embodiments, when the medical history information indicates that the subject has a history of anemia or tuberculosis, step 130 selects a second sampling mode according to the medical history information. Generally speaking, if the subject has a history of anemia or tuberculosis, the actual or expected erythrocyte sedimentation degree during sampling will be relatively high and large.

[0237] For the acquisition of medical history information, reference can be made to the above, which will not be elaborated here.

[0238] In some embodiments, the test results of the second type of test items of the sample to be tested include the test results of the routine blood test erythroid series of the sample to be tested and / or the erythrocyte sedimentation test results of the sample to be tested. In some embodiments, the test results of the routine blood test erythroid series include at least one of hemoglobin concentration, hematocrit, and erythrocyte aggregation index. Among them, the higher the hemoglobin concentration of the sample to be tested, the lower the current actual or expected erythrocyte sedimentation degree of the sample to be tested; the higher the hematocrit of the sample to be tested, the lower the current actual or expected erythrocyte sedimentation degree of the sample to be tested; the higher the hemoglobin concentration of the sample to be tested, the lower the current actual or expected erythrocyte sedimentation degree of the sample to be tested.

[0239] In some embodiments, when the hemoglobin concentration of the sample to be tested is less than the first value, step 130 selects a second sampling mode according to the test result of the hemoglobin concentration; otherwise, it selects the first sampling mode.

[0240] In some embodiments, when the hematocrit of the sample to be tested is less than the second value, step 130 selects a second sampling mode according to the test result of the hematocrit; otherwise, it selects the first sampling mode.

[0241] In some embodiments, when the erythrocyte aggregation index of the sample to be tested is less than the third value, step 130 selects a second sampling mode according to the test result of the erythrocyte aggregation index; otherwise, it selects the first sampling mode.

[0242] In some embodiments, the erythrocyte sedimentation test results include direct erythrocyte sedimentation results and / or indirect erythrocyte sedimentation results.

[0243] In some embodiments, when the erythrocyte sedimentation test result of the sample to be tested is greater than the fourth value, step 130 selects a second sampling mode according to the test result of the erythrocyte sedimentation test; otherwise, it selects the first sampling mode.

[0244] In some embodiments, step 130 can obtain the test results of the second type of test items of the sample to be tested through, such as, an LIS system. The LIS system (Laboratory Information System) is the laboratory (clinical laboratory) information system, which is one of the important components of hospital information management.

[0245] In some embodiments, the sample analysis device 100 itself is capable of performing a second type of test item. Therefore, step 130 can obtain the test result based on the second type of test item performed on the sample to be tested on the device itself. For example, step 130 can control the sample to be tested to first perform the second type of test item, and then perform the first type of test item after the test result is obtained. In some embodiments, the second type of test item can be the same test item as the third type of item mentioned in this document, or the two include some identical test items.

[0246] In some embodiments, the first image information of the sample to be tested can characterize the erythrocyte sedimentation degree of the sample to be tested. In some embodiments, when it is determined based on the first image information of the sample to be tested that the erythrocyte sedimentation degree of the sample to be tested is low - for example, most of the erythrocytes are focused on the upper-middle part of the sample container, then step 130 selects the first sampling mode according to the test result of the erythrocyte sedimentation test. Conversely, the second sampling mode is selected.

[0247] In some embodiments, the information of the sample to be tested includes the first image information of the sample to be tested. Step 130 can select one of at least the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing a target item, such as the first type of item, based on the first image information of the sample to be tested.

[0248] In some embodiments, the shooting timing can be before sampling the sample to be tested. For example, before step 130 determines which sampling mode to use for the sample to be tested. Step 130 can obtain the first image information of the sample to be tested through the camera 91 mentioned above.

[0249] In some embodiments, the first image information and the second image information of the sample to be tested are the image information obtained by the camera 92 taking the same shot of the sample to be tested.

[0250] The above are some descriptions for determining whether to use the first sampling mode or the second sampling mode as the sampling mode for the sample to be tested when performing a target item, such as the first type of item, based on the information of the sample to be tested.

[0251] Judging the speed or degree of erythrocyte sedimentation of the sample to be tested through the information of the sample to be tested, so as to determine whether to use the first sampling mode or the second sampling mode as the sampling mode for the sample to be tested when performing a target item, such as the first type of item, can achieve a better balance between the sampling stroke of the sample needle 11 and factors such as erythrocyte sedimentation that affect sampling and test results.

[0252] In some embodiments, step 130 can select one of a first sampling mode, a second sampling mode, and a third sampling mode as the sampling mode for the sample to be tested when performing the target item based on the sample type and the information of the sample to be tested. When the sample type is a whole blood sample, it indicates that the sampling mode of the sample to be tested is the first sampling mode or the second sampling mode, and step 130 can select one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the sample type is a serum sample, it indicates that the sampling mode of the sample to be tested is the third sampling mode, so step 130 selects the third sampling mode as the sampling mode for the sample to be tested when performing the target item.

[0253] In some embodiments, the information of the sample to be tested can characterize the sample type; in such an example, step 130 can then select one of a first sampling mode, a second sampling mode, and a third sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested.

[0254] In some embodiments, step 130 can select one of a first sampling mode, a second sampling mode, and a third sampling mode as the sampling mode for the sample to be tested when performing the target item based on the target item to be performed on the sample to be tested and the information of the sample to be tested. When the target item to be performed on the sample to be tested is a first type of item, it indicates that the sampling mode of the sample to be tested is the first sampling mode or the second sampling mode, and step 130 can select one of the first sampling mode and the second sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the target item to be performed on the sample to be tested is a third type of item, it indicates that the sampling mode of the sample to be tested is the third sampling mode, so step 130 selects the third sampling mode as the sampling mode for the sample to be tested when performing the target item.

[0255] In some embodiments, the information of the sample to be tested can characterize whether the target item to be performed on the sample to be tested is a first type of item or a third type of item; in such an example, step 130 can then select one of a first sampling mode, a second sampling mode, and a third sampling mode as the sampling mode for the sample to be tested when performing the target item based on the information of the sample to be tested.

[0256] In some embodiments, step 130 can select one of a first sample aspiration mode, a second sample aspiration mode, and a third sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item based on the sample type, the target item to be performed on the sample to be tested, and the information of the sample to be tested. When the sample type is a whole blood sample and the target item to be performed is a first type of item, it indicates that the sample aspiration mode of the sample to be tested is the first sample aspiration mode or the second sample aspiration mode, and step 130 can select one of the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the sample type is a serum sample and the target item to be performed is a third type of item, it indicates that the sample aspiration mode of the sample to be tested is the third sample aspiration mode. Therefore, step 130 selects the third sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item.

[0257] In some embodiments, the information of the sample to be tested can characterize the sample type and / or whether the target item to be performed on the sample to be tested is a first type of item or a third type of item.

[0258] In some embodiments, the third sample aspiration mode and the first sample aspiration mode can be the same sample aspiration mode.

[0259] Therefore, in some embodiments, step 130 can select one of the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item based on the sample type and the information of the sample to be tested. When the sample type is a whole blood sample, step 130 can select one of the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item based on the information of the sample to be tested; when the sample type is a serum sample, it indicates that the sample aspiration mode of the sample to be tested is the first sample aspiration mode. Therefore, step 130 selects the first sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item.

[0260] In some embodiments, the information of the sample to be tested can characterize the sample type; in such an example, step 130 can then select one of the first sample aspiration mode and the second sample aspiration mode as the sample aspiration mode for the sample to be tested when performing the target item based on the information of the sample to be tested.

[0261] In some embodiments, step 130 can select one of the first sampling mode and the second sampling mode as the sampling mode for the test sample when performing the target item based on the target item to be performed on the test sample and the information of the test sample. When the target item to be performed on the test sample is a first type of item, step 130 can select one of the first sampling mode and the second sampling mode as the sampling mode for the test sample when performing the target item; when the target item to be performed on the test sample is a third type of item, it indicates that the sampling mode of the test sample is the third sampling mode. Therefore, step 130 selects the third sampling mode as the sampling mode for the test sample when performing the target item.

[0262] In some embodiments, the information of the test sample can characterize whether the target item to be performed on the test sample is a first type of item or a third type of item; in such an example, step 130 can then select one of the first sampling mode and the second sampling mode as the sampling mode for the test sample when performing the target item based on the information of the test sample.

[0263] In some embodiments, step 130 can select one of the first sampling mode and the second sampling mode as the sampling mode for the test sample when performing the target item based on the sample type, the target item to be performed on the test sample, and the information of the test sample. When the sample type is a whole blood sample and the target item to be performed is a first type of item, step 130 can select one of the first sampling mode and the second sampling mode as the sampling mode for the test sample when performing the target item; when the sample type is a serum sample and the target item to be performed is a third type of item, it indicates that the sampling mode of the test sample is the third sampling mode. Therefore, step 130 selects the third sampling mode as the sampling mode for the test sample when performing the target item.

[0264] In some embodiments, the information of the test sample can characterize the sample type and / or whether the target item to be performed on the test sample is a first type of item or a third type of item.

[0265] Please refer to Figure 10 , the sample analysis method of some embodiments further includes step 112: when the target item applied for by the test sample is a first type of item, set the test sample as an emergency sample, so as to preferentially test the test sample and preferentially sample. This can further reduce the influence of factors such as erythrocyte sedimentation rate on the sampling and test results.

[0266] A simple combination of emergency and two sampling modes can yield more solutions. In some embodiments, when the target item of the sample to be tested is a first type of item, in step 112, the sample to be tested is set as an emergency sample, so as to preferentially test and preferentially sample the sample to be tested; when determining the sampling mode of the sample to be tested for the first type of item, in step 130, according to the information of the sample to be tested, one of at least a first sampling mode and a second sampling mode is selected as the sampling mode of the sample to be tested when performing the first type of item. For example, when the information of the sample to be tested indicates a relatively high erythrocyte sedimentation rate or a relatively high degree of erythrocyte sedimentation, then in step 130, the second sampling mode is used as the sampling mode of the sample to be tested when performing the first type of item. On the contrary, in step 130, the first sampling mode is used as the sampling mode of the sample to be tested when performing the first type of item.

[0267] In addition, in some embodiments, when the target item of the sample to be tested is a first type of item, in step 112, the sample to be tested is set as an emergency sample, so as to preferentially test and preferentially sample the sample to be tested; in this case, in step 130, it can also be determined that the sampling mode of the sample to be tested when performing the first type of item is uniformly the first sampling mode or uniformly the second sampling mode, rather than having to select one of at least a first sampling mode and a second sampling mode as the sampling mode of the sample to be tested when performing the first type of item according to the information of the sample to be tested.

[0268] This document is described with reference to various exemplary embodiments. However, those skilled in the art will recognize that changes and modifications can be made to the exemplary embodiments without departing from the scope of this document. For example, various operation steps and the components for performing the operation steps can be implemented in different ways according to a specific application or considering any number of cost functions associated with the operation of the system (e.g., one or more steps can be deleted, modified, or combined into other steps).

[0269] In the above embodiments, it can be implemented in whole or in part by software, hardware, firmware, or any combination thereof. Additionally, as understood by those skilled in the art, the principles herein can be embodied in a computer program product on a computer-readable storage medium that is preloaded with computer-readable program code. Any tangible, non-transitory computer-readable storage medium can be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROMs, DVDs, Blu-ray discs, etc.), flash memories, and / or the like. These computer program instructions can be loaded onto a general-purpose computer, a special-purpose computer, or other programmable data processing devices to form a machine, such that the instructions executed on the computer or other programmable data processing devices can generate a device for implementing the specified functions. These computer program instructions can also be stored in a computer-readable memory, which can direct the computer or other programmable data processing devices to operate in a specific manner, so that the instructions stored in the computer-readable memory can form a manufactured article, including a device for implementing the specified functions. The computer program instructions can also be loaded onto a computer or other programmable data processing devices, thereby performing a series of operation steps on the computer or other programmable devices to generate a computer-implemented process, such that the instructions executed on the computer or other programmable devices can provide steps for implementing the specified functions.

[0270] Although the principles herein have been shown in various embodiments, many modifications of the structures, arrangements, proportions, elements, materials, and components, which are particularly applicable to specific environments and operational requirements, may be used without departing from the principles and scope of this disclosure. The above modifications and other changes or revisions will be included within the scope of this disclosure.

[0271] The foregoing detailed description has been described with reference to various embodiments. However, those skilled in the art will recognize that various modifications and changes can be made without departing from the scope of this disclosure. Therefore, the consideration of this disclosure will be in an illustrative rather than a restrictive sense, and all such modifications will be included within its scope. Similarly, the advantages, other advantages, and solutions to problems of the various embodiments have been described above. However, benefits, advantages, solutions to problems, and any elements that can produce these, or solutions that make them more explicit, should not be construed as critical, essential, or necessary. The term "comprising" and any other variants used herein are non-exclusive inclusions, such that a process, method, article, or device that includes a list of elements not only includes those elements but also other elements not explicitly listed or belonging to the process, method, system, article, or device. Additionally, the term "coupled" and any other variants used herein refer to physical connection, electrical connection, magnetic connection, optical connection, communication connection, functional connection, and / or any other connection.

[0272] Those skilled in the art will recognize that many changes may be made to the details of the above-described embodiments without departing from the basic principles of the present invention. Therefore, the scope of the present invention should be determined solely by the claims.

Claims

1. A sample analysis device, characterized in that: include: Dispensing components, reagent components, reaction components, detection components and controllers; The dispensing component includes a sample needle, and the sample needle is used to draw the sample to be tested from the sample container containing the sample and dispense it to the reaction component; The reagent component is used to provide reagents to the reaction component; The reaction component is used to form a reaction solution based on the sample to be tested and the reagent; The detection component is used to detect the reaction liquid to obtain the detection result of the target item; The controller is used to select one of at least a first sampling mode and a second sampling mode as the sampling mode of the sample to be tested when the target item is a first category item, according to information of the sample to be tested, wherein in the first sampling mode: the sample needle extends into the sample container and absorbs the sample to be tested at a first height; in the second sampling mode: the sample needle extends into the sample container and absorbs the sample to be tested at a second height, the first height is greater than the second height, and the sample to be tested corresponding to the first category item is a whole blood sample.

2. A sample analysis device, characterized in that: include: Dispensing components, reagent components, reaction components, detection components and controllers; The dispensing component is used to draw the sample to be tested from the sample container containing the sample to be tested and dispense it to the reaction component; the sample container includes a first sample container and a second sample container, and the specification of the second sample container is smaller than that of the first sample container; The reagent component is used to provide reagents to the reaction component; The reaction component is used to form a reaction solution based on the sample to be tested and the reagent; The detection component is used to detect the reaction liquid to obtain the detection result of the target item; The controller is used to select one of at least a first sampling mode and a second sampling mode as the sampling mode of the sample to be tested when the target project is a first category project, according to information of the sample to be tested, in the first sampling mode: the dispensing component draws the sample to be tested from the first sample container and dispenses it to the reaction component; in the second sampling mode: the dispensing component draws the sample to be tested from the first sample container and dispenses it to the second sample container, and then draws the sample to be tested from the second sample container and dispenses it to the reaction component; the sample to be tested corresponding to the first category project is a whole blood sample.

3. The sample analysis device according to claim 1 or 2, characterized in that: The information of the sample to be tested is used to characterize the erythrocyte sedimentation rate of the sample to be tested. When the sample to be tested selects the first sampling mode, the erythrocyte sedimentation rate characterized by the information of the sample to be tested is less than the erythrocyte sedimentation rate characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode.

4. The sample analysis device according to claim 3, characterized in that: The information of the sample to be tested includes at least one of the following: medical history information of the subject to whom the sample to be tested belongs, and the test result of the second category of test items of the sample to be tested.

5. The sample analysis device according to claim 4, characterized in that: When the medical history information indicates that the subject has a medical history of anemia or tuberculosis, the controller selects the second sample suction mode according to the medical history information.

6. The sample analysis device according to claim 4, characterized in that: The test results of the second category of test items of the sample to be tested include the blood routine erythrocyte test results of the sample to be tested and / or the erythrocyte sedimentation rate test results of the sample to be tested; the blood routine erythrocyte test results include at least one of hemoglobin concentration, hematocrit and red blood cell aggregation index, wherein, the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte sedimentation rate of the sample to be tested, the higher the hematocrit of the sample to be tested, the smaller the erythrocyte sedimentation rate of the sample to be tested, and the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte aggregation index of the sample to be tested.

7. The sample analysis device according to claim 1 or 2, characterized in that: The information of the sample to be tested is used to characterize the red blood cell sedimentation degree of the sample to be tested. When the sample to be tested selects the first sampling mode, the red blood cell sedimentation degree represented by the information of the sample to be tested is lower than the red blood cell sedimentation degree represented by the information of the sample to be tested when the sample to be tested selects the second sampling mode. 8 . The sample analysis device according to claim 1 , wherein the information of the sample to be tested comprises first image information of the sample to be tested.

9. The sample analysis device according to claim 1 or 2, characterized in that: When the target project applied for by the sample to be tested is the first category project, the controller sets the sample to be tested as an emergency sample.

10. The sample analysis device according to claim 1, 8 or 9, characterized in that: The first category of items includes at least one of glycated hemoglobin, glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase.

11. The sample analysis device according to claim 1 or 2, characterized in that: The controller also obtains second image information of the sample to be tested. When it is determined that there is a risk of needle blockage during sample aspiration based on the second image information of the sample to be tested, the controller controls the sample needle to stop aspirating the sample to be tested and issues a prompt; when there is no risk of needle blockage, the controller controls the sample needle to aspirate the sample to be tested from the sample container containing the sample to be tested and dispenses it into the reaction component.

12. The sample analysis device according to claim 1 or 2, characterized in that: The whole blood sample is a whole blood sample that has been mixed.

13. The sample analysis device according to claim 1, wherein: In the first sample aspiration mode and the second sample aspiration mode, the cleaning parameters of the sample needle are different.

14. The sample analysis device according to claim 1 or 2, characterized in that: When the target item is a third category item, the controller controls the dispensing component to adopt a third sample suction mode to draw the sample to be tested from the sample container containing the sample to be tested and dispense it to the reaction component, and the sample to be tested corresponding to the third category item is a serum sample; the detection component includes a light source component and a photometric component, the light source component is used to generate irradiation light to irradiate the reaction liquid, and the photometric component is used to detect a light signal corresponding to the transmitted light and / or scattered light formed after the irradiation light passes through the reaction liquid, and the detection result of the target item is obtained according to the light signal.

15. The sample analysis device according to claim 2, wherein: The dispensing component includes a sample needle. In the first sample suction mode: the sample needle extends into the first sample container and absorbs the sample at a first height; in the second sample suction mode: the sample needle extends into the first sample container and absorbs the sample to be tested at the first height, and the sample needle extends into the second sample container and absorbs the sample to be tested at the first height.

16. A sample analysis method, characterized in that: include: Obtain the target project applied for by the sample to be tested; Obtaining information of the sample to be tested; When the target item is a first category item, according to the information of the sample to be tested, one of at least the first sampling mode and the second sampling mode is selected as the sampling mode of the sample to be tested when performing the first category item. In the first sampling mode: the sample needle is controlled to extend into the sample container and absorb the sample to be tested at a first height. In the second sampling mode: the sample needle is controlled to extend into the sample container and absorb the sample to be tested at a second height. The first height is greater than the second height. The sample to be tested corresponding to the first category item is a whole blood sample.

17. A sample analysis method, characterized in that: include: Obtain the target project applied for by the sample to be tested; Obtaining information of the sample to be tested; When the target project is a first category project, according to the information of the sample to be tested, one of at least the first sampling mode and the second sampling mode is selected as the sampling mode of the sample to be tested when performing the first category project. In the first sampling mode: control the sample to be tested to be sucked from the first sample container and dispensed to the reaction component; in the second sampling mode: control the dispensing component to suck the sample to be tested from the first sample container and dispense it to the second sample container, and then suck the sample to be tested from the second sample container and dispense it to the reaction component; the specification of the second sample container is smaller than that of the first sample container, and the sample to be tested corresponding to the first category project is a whole blood sample.

18. The sample analysis method according to claim 16 or 17, characterized in that: The information of the sample to be tested is used to characterize the erythrocyte sedimentation rate of the sample to be tested, and when the sample to be tested selects the first sampling mode, the erythrocyte sedimentation rate characterized by the information of the sample to be tested is less than the erythrocyte sedimentation rate characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode; and / or, the information of the sample to be tested is used to characterize the erythrocyte sedimentation degree of the sample to be tested, and when the sample to be tested selects the first sampling mode, the erythrocyte sedimentation degree characterized by the information of the sample to be tested is less than the erythrocyte sedimentation degree characterized by the information of the sample to be tested when the sample to be tested selects the second sampling mode.

19. The sample analysis method according to claim 18, characterized in that: The information of the sample to be tested includes at least one of the following: medical history information of the subject to whom the sample to be tested belongs, and the test result of the second category of test items of the sample to be tested.

20. The sample analysis method according to claim 19, characterized in that: When the medical history information indicates that the subject has a medical history of anemia or tuberculosis, the controller selects the second sample suction mode according to the medical history information.

21. The sample analysis method according to claim 19, characterized in that: The test results of the second category of test items of the sample to be tested include the blood routine erythrocyte test results of the sample to be tested and / or the erythrocyte sedimentation rate test results of the sample to be tested; the blood routine erythrocyte test results include at least one of hemoglobin concentration, hematocrit and red blood cell aggregation index, wherein, the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte sedimentation rate of the sample to be tested, the higher the hematocrit of the sample to be tested, the smaller the erythrocyte sedimentation rate of the sample to be tested, and the higher the hemoglobin concentration of the sample to be tested, the smaller the erythrocyte aggregation index of the sample to be tested.

22. The sample analysis method according to claim 16 or 17, characterized in that: The first category of items includes at least one of glycated hemoglobin, glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase.

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