Sample analyzer and sample analysis method

Abstract

The embodiment of the invention provides a sample analyzer and a sample analysis method.The sample analysis method comprises the steps that an analyzer execution main body is controlled to execute first pretreatment operation on a sample, and the first pretreatment operation comprises the steps that the analyzer execution main body is controlled to inject the sample and a first magnetic bead reagent into a first reaction container; mixing the sample and the first magnetic bead reagent to form a first mixed solution; the analyzer execution main body is controlled to magnetically adsorb the first mixed solution, so that the first mixed solution is separated to form first magnetic bead particles and a first to-be-detected solution, and the first to-be-detected solution contains a to-be-detected substance; after the execution of the first pretreatment operation is completed, the analyzer execution main body is controlled to suck a first to-be-detected liquid from the first reaction container and separately inject the first to-be-detected liquid into a second reaction container, and a first target reagent is injected into the second reaction container to prepare a first target reaction liquid; and controlling the analyzer execution main body to detect the first target reaction liquid, and outputting a first detection result.

Description

Technical Field

[0001] This application relates to the technical field of medical devices, and particularly to a sample analyzer and a sample analysis method. Background Art

[0002] Taking an immunoassay analyzer as an example, this is a type of analytical instrument with high sensitivity and high specificity, and is often used in clinical laboratories to detect various immune indexes in blood, urine or other body fluids. The principle is the combination of antibody-antigen reaction and chemiluminescence technologies to achieve high specificity and high sensitivity.

[0003] During the sample detection process, since there are usually some interfering substances in the sample that can affect the detection results, the detection results of the immunoassay analyzer are inaccurate.

[0004] In related technologies, to solve the problem of inaccurate detection results, usually the sample is diluted multiple times to reduce the concentration of interfering substances in the sample, and then the diluted sample is retested. However, multiple dilutions and retesting of the sample greatly reduce the detection efficiency, and the concentration of the active ingredients in the sample after multiple dilutions will also decrease, affecting the accuracy of sample detection. Summary of the Invention

[0005] The main purpose of the embodiments of this application is to provide a sample analyzer and a sample analysis method, aiming to solve the problem of inaccurate detection results.

[0006] In a first aspect, the embodiments of this application provide a sample analyzer, including:

[0007] An analyzer execution body and a controller communicatively connected to the analyzer execution body, where the analyzer execution body at least includes a dispensing device, a reaction device, a magnetic adsorption device, and a detection device;

[0008] The dispensing device is at least used for dispensing samples and / or reagents;

[0009] The reaction device is provided with at least one reaction position for placing a reaction container, and the reaction container is used to receive the samples and reagents dispensed by the dispensing device;

[0010] The magnetic adsorption device is used for magnetically adsorbing the mixed solution, and the mixed solution is at least formed by mixing a sample and a pretreated magnetic bead reagent;

[0011] The detection device is used for detecting the reaction solution to obtain corresponding detection data;

[0012] The controller is at least used for:

[0013] Control the analyzer execution entity to perform a first pretreatment operation on the sample. The first pretreatment operation includes: controlling the dispensing device to dispense the sample and a first magnetic bead reagent into the first reaction container, so that the sample and the first magnetic bead reagent are mixed to form a first mixed solution, and the first magnetic bead reagent is used to adsorb interfering substances in the sample; and controlling the magnetic adsorption device to perform magnetic adsorption on the first mixed solution, so that the first mixed solution is separated to form a first magnetic bead particulate matter and a first test solution, and the first test solution contains the analyte;

[0014] After the first pretreatment operation is completed, control the dispensing device to aspirate the first test solution from the first reaction container and dispense it into the second reaction container, and add a first target reagent to the second reaction container to prepare a first target reaction solution;

[0015] Control the detection device to detect the first target reaction solution to obtain first detection data.

[0016] In a second aspect, an embodiment of the present application further provides a sample analyzer, including:

[0017] An analyzer execution entity and a controller communicatively connected to the analyzer execution entity. The analyzer execution entity at least includes a dispensing device, a reaction device, a magnetic adsorption device, and a detection device;

[0018] The dispensing device is at least used for dispensing samples and / or reagents;

[0019] The reaction device is provided with at least one reaction position for placing a reaction container, and the reaction container is used to receive the samples and reagents dispensed by the dispensing device;

[0020] The magnetic adsorption device is used to perform magnetic adsorption on the mixed solution, and the mixed solution is at least formed by mixing a sample and a pretreatment magnetic bead reagent;

[0021] The detection device is used to detect the reaction solution to obtain corresponding detection data;

[0022] The controller is at least used for:

[0023] Control the analyzer execution body to perform a second pretreatment operation on the sample. The second pretreatment operation includes: controlling the analyzer execution body to dispense the sample and a second magnetic bead reagent into a third reaction container so that the sample and the second magnetic bead reagent are mixed to form a second mixed solution, and the second magnetic bead reagent is used to adsorb the analyte in the sample; controlling the analyzer execution body to perform magnetic adsorption on the second mixed solution so that the second mixed solution is separated into a second magnetic bead particulate matter and a second liquid, and controlling the analyzer execution body to aspirate the second liquid in the third reaction container; controlling the analyzer execution body to dispense a displacement reagent into the third reaction container carrying the second magnetic bead particulate matter so that the displacement reagent and the second magnetic bead particulate matter are mixed to form a third mixed solution, and the displacement reagent is used to displace the analyte from the second magnetic bead particulate matter; controlling the analyzer execution body to perform magnetic adsorption on the third mixed solution so that the third mixed solution is separated into a third magnetic bead particulate matter and a second analyte solution, and the second analyte solution contains the analyte;

[0024] After the second pretreatment operation is completed, control the analyzer execution body to aspirate the second analyte solution and dispense it into a fourth reaction container, and dispense a third target reagent into the fourth reaction container to prepare a third target reaction solution;

[0025] Control the analyzer execution body to detect the third target reaction solution to obtain third detection data.

[0026] In a third aspect, an embodiment of the present application further provides a sample analysis method applied to a sample analyzer. The sample analyzer includes an analyzer execution body. The method includes:

[0027] Control the analyzer execution body to perform a first pretreatment operation on the sample. The first pretreatment operation includes: controlling the dispensing device of the analyzer execution body to add the sample and a first magnetic bead reagent into a first reaction container so that the sample and the first magnetic bead reagent are mixed to form a first mixed solution, and the first magnetic bead reagent is used to adsorb the interfering substances in the sample; and controlling the magnetic adsorption device of the analyzer execution body to perform magnetic adsorption on the first mixed solution so that the first mixed solution is separated into a first magnetic bead particulate matter and a first analyte solution, and the first analyte solution contains the analyte;

[0028] After the first pretreatment operation is completed, control the dispensing device to aspirate the first analyte solution from the first reaction container and dispense it into a second reaction container, and add a first target reagent to the second reaction container to prepare a first target reaction solution;

[0029] Control the detection device of the analyzer execution body to detect the first target reaction solution and output a first detection result.

[0030] In a fourth aspect, an embodiment of the present application further provides a sample analysis method applied to a sample analyzer. The sample analyzer includes an analyzer execution body. The method includes:

[0031] The analyzer execution body of the sample analyzer performs a second pretreatment operation on the sample. The second pretreatment operation includes: controlling the analyzer execution body to dispense the sample and a second magnetic bead reagent into a third reaction vessel so that the sample and the second magnetic bead reagent are mixed to form a second mixed solution, where the second magnetic bead reagent is used to adsorb the analyte in the sample; controlling the analyzer execution body to perform magnetic adsorption on the second mixed solution so that the second mixed solution is separated to form second magnetic bead particles and a second liquid, and controlling the analyzer execution body to aspirate the second liquid in the third reaction vessel; controlling the analyzer execution body to dispense a displacement reagent into the third reaction vessel carrying the second magnetic bead particles so that the displacement reagent and the second magnetic bead particles are mixed to form a third mixed solution, where the displacement reagent is used to displace the analyte from the second magnetic bead particles; controlling the analyzer execution body to perform magnetic adsorption on the third mixed solution so that the third mixed solution is separated to form third magnetic bead particles and a second analyte solution, and the second analyte solution contains the analyte;

[0032] After the second pretreatment operation is completed, control the analyzer execution body to aspirate the first analyte solution from the first reaction vessel and dispense it into the second reaction vessel, and dispense the third target reagent into the fourth reaction vessel to prepare a third target reaction solution;

[0033] Control the analyzer execution body to detect the third target reaction solution to obtain third detection data.

[0034] As can be seen from the technical solutions provided in the present application above, during the detection of the sample to be tested by the sample analyzer, by adding the sample and the first magnetic bead reagent into the first reaction vessel to form a first mixed solution, the first magnetic bead reagent is used to adsorb the interfering substances in the sample, that is, the first magnetic bead reagent is used to combine with the interfering substances in the sample to form first magnetic bead particles, so that the effective analyte in the sample remains in the solution. At the same time, the magnetic adsorption device is used to perform magnetic adsorption on the first mixed solution, and the first magnetic bead particles and the first analyte solution containing the analyte are separated by the magnetic force, thereby completing the impurity removal pretreatment of the sample. After the sample pretreatment is completed, the first analyte solution with the analyte in the first reaction vessel is aspirated by the dispensing device and the first analyte solution is dispensed into the second reaction vessel, and the first target reagent is dispensed into the second reaction vessel, so that the first analyte solution with the analyte and the first target reagent are mixed to form a first target reaction solution. Based on the impurity removal pretreatment of the sample, the concentration of impurities in the sample can be effectively reduced, so that it is not necessary to dilute the sample multiple times, effectively improving the efficiency of sample detection. And after the impurity removal pretreatment, the concentration of impurities in the first target reaction solution formed by mixing the first analyte solution and the first target reagent can be effectively reduced. Furthermore, by detecting the first target reaction solution, the accuracy of sample analysis can be effectively improved.

[0035] Alternatively, during the detection of the sample to be tested, the sample analyzer adds the sample and the second magnetic bead reagent to the third reaction vessel to form a second mixture. The second magnetic bead reagent is used to adsorb the analyte in the sample. That is, the second magnetic bead particulate is formed by the combination of the second magnetic bead reagent and the analyte in the sample. At this time, the impurities in the sample are retained in the solution. The second mixture is separated by magnetic adsorption to form the second magnetic bead particulate and the second liquid. At this time, the second liquid is aspirated out, and a replacement reagent is added to the third reaction vessel carrying the second magnetic bead particulate to displace the analyte attached to the second magnetic bead particulate into the solution to form a second test solution, thereby completing the impurity removal pretreatment of the sample. After the sample pretreatment is completed, the dispensing device aspirates the second test solution containing the analyte in the third reaction vessel and distributes the second test solution to the fourth reaction vessel, and the third target reagent is dispensed into the fourth reaction vessel, so that the second test solution containing the analyte and the third target reagent are mixed to form a third target reaction solution. Based on the impurity removal pretreatment of the sample, the concentration of impurities in the sample can be effectively reduced, so that the sample does not need to be diluted multiple times, effectively improving the efficiency of sample detection. And after the impurity removal pretreatment, the concentration of impurities in the third target reaction solution formed by mixing the second test solution and the third target reagent can be effectively reduced. Furthermore, by detecting the third target reaction solution, the accuracy of sample analysis can be effectively improved.

[0036] It should be understood that the above general description and the following detailed description are only exemplary and explanatory, and cannot limit the disclosure of the embodiments of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for the description of the embodiments will be briefly introduced below. Obviously, the drawings in the following description are some embodiments of the present application. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0038] Figure 1 is a block diagrammatic structural schematic diagram of a sample analyzer in an embodiment;

[0039] Figure 2 is a structural layout schematic diagram of a sample analyzer in an embodiment;

[0040] Figure 3 is a structural schematic diagram of a dispensing device of a sample analyzer in an embodiment;

[0041] Figure 4 is a schematic diagram of a scenario where a sample analyzer performs a first pretreatment operation on a sample in an embodiment;

[0042] Figures 5 to 6It is a schematic diagram of the scenario where a sample analyzer performs a second preprocessing operation on a sample in an embodiment. Specific Embodiments

[0043] Next, the technical solutions in the embodiments of the present application will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present application without creative efforts shall fall within the protection scope of the present application.

[0044] In the description of the present application, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" shall be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific situations.

[0045] The flowcharts shown in the accompanying drawings are only illustrative examples, and do not necessarily include all the contents and operations / steps, nor do they necessarily need to be executed in the described order. For example, some operations / steps can also be decomposed, combined, or partially merged, so the actual execution order may be changed according to the actual situation.

[0046] Next, some embodiments of the present application will be described in detail in conjunction with the accompanying drawings. Without conflict, the features in the following embodiments and embodiments can be combined with each other.

[0047] Please refer to Figure 1 , the present application provides a sample analyzer for analyzing a sample to be tested to obtain corresponding analysis results.

[0048] In some embodiments, the sample analyzer includes but is not limited to at least one of the following: a biochemical analyzer, an immunoassay analyzer, a coagulation analyzer, and a urine analyzer.

[0049] As Figure 1 shown, the sample analyzer 100 includes an analyzer execution body (not shown in the figure) and a controller 70 communicatively connected to the analyzer execution body. The analyzer execution body includes a dispensing device 10, a sample supply device 20, a reagent supply device 30, a reaction device 40, a magnetic adsorption device 50, and a detection device 60.

[0050] The sample supply device 20 is used to provide samples to be tested, and the reagent supply device 30 is used to provide reagents that react with the samples. Among them, the reagents include, but are not limited to, chromogenic reagents, diluents, substrate solutions, enzyme-labeled reagents, magnetic bead reagents, etc. The dispensing device 10 is used to dispense samples and / or reagents. The reaction device 40 is provided with at least one reaction position for placing reaction containers. The reaction container is used to receive samples and reagents and provide a mixing place for the samples and reagents. The reaction container includes, but is not limited to, reaction cups. For example, the sample analyzer 100 is provided with a sample suction position and a reagent suction position. During the mixing process of the sample and the reagent, the dispensing device 10 sucks the sample supplied by the sample supply device 20 at the sample suction position and the reagent supplied by the reagent supply device 30 at the reagent suction position, and respectively dispenses the sucked sample and reagent into the reaction container placed at the preset operation position.

[0051] Optionally, the reaction device 40 is also used to incubate the mixture formed by mixing the sample and the reagent.

[0052] The magnetic adsorption device 50 is used to perform magnetic adsorption operations to agglomerate the magnetic particles in the solution carried by the reaction container, so as to achieve the rapid separation of the magnetic particles and the liquid in the solution carried by the reaction container.

[0053] The detection device 60 is used to detect the reaction solution to obtain detection data. For example, the detection device 60 is used to measure the reaction solution in the reaction container to obtain the reaction data of the sample.

[0054] Optionally, the detection device 60 includes a photometric mechanism. The photometric mechanism is used to detect the luminescence intensity of the reaction solution, and calculate the concentration of the component to be measured in the sample through a calibration curve. Optionally, the detection device 60 is separately arranged on the periphery of the reaction device 40.

[0055] In another embodiment, the detection device 60 includes an electrical detection mechanism (such as an impedance measurement mechanism) or a detection mechanism based on other principles (such as an imaging measurement mechanism).

[0056] Those skilled in the art should understand that Figure 1 This is only an example of the sample analyzer 100 and does not constitute a limitation on the sample analyzer 100. The sample analyzer 100 may include Figure 1 more or fewer components than shown, or combine some components, or different components. For example, the sample analyzer 100 may also include input / output devices, network access devices, etc.

[0057] Please refer to Figure 2, in some embodiments, the reaction device 40 has a support portion 401, and at least one reaction site is provided on the support portion 401. The reaction site is used to place a reaction vessel (such as a reaction cup 4011). The reaction vessel is used to receive samples and reagents and provide a reaction site for the samples and reagents. For example, the reaction vessel receives the sample obtained by the dispensing device 10 from the sample supply device 20 and the reagent obtained from the reagent supply device 30, so that the sample and the reagent are mixed in the reaction vessel.

[0058] Optionally, the support portion 401 of the reaction device 40 may be a reaction disk, such as Figure 2 As shown, it is arranged as a disk-shaped component and has one or more reaction sites for placing reaction vessels. The reaction disk can incubate the reaction solution in the reaction vessel and can rotate to drive the reaction vessel placed in the reaction site to rotate, so as to realize the scheduling of the reaction vessel in the reaction disk within a preset area. For example, the reaction vessel located in the reaction site is scheduled to the position for reagent addition.

[0059] It can be understood that the reaction site for carrying the reaction vessel can be provided not only on the reaction disk of the reaction device 40 but also independently of the reaction disk of the reaction device 40. The reaction site being provided independently of the reaction disk means that the setting of the reaction site does not interfere with the rotation of the reaction disk itself.

[0060] Please refer to Figures 2 to 3 , in some embodiments, the sample supply device 20 may include a sample distribution module (SDM, Sample Delivery Module) and a front-end track; the sample supply device 20 may also be a sample disk. The sample disk includes a plurality of sample positions for placing sample tubes such as sample tubes. By rotating its disk-shaped component, the sample disk can schedule the sample to the corresponding position. For example, the sample is scheduled to the sample suction position where the dispensing device 10 sucks the sample. The dispensing device 10 is used to suck the sample and discharge it into the reaction vessel to be loaded with the sample.

[0061] In some embodiments, the dispensing device 10 is used to dispense samples and / or reagents. For example, the dispensing device 10 sucks the sample supplied by the sample supply device 20 and transfers the sample to the reaction vessel to be loaded with the sample.

[0062] Optionally, the dispensing device 10 includes a sample dispensing device 10a. The sample dispensing device 10a is configured to aspirate the sample supplied by the sample supply device 20 and transfer the sample to a preset position. For example, the sample supply device 20 carries a sample container containing the sample to be tested. The sample container includes but is not limited to a sample tube. The sample dispensing device 10a aspirates the sample to be tested from the sample tube carried by the sample supply device 20 and discharges the sample into the reaction container to be loaded with the sample. Alternatively, the sample supply device 20 carries a sample tube containing the sample to be tested. The scheduling device of the analyzer main body schedules the sample tube containing the sample to be tested to the sample aspiration position. The sample dispensing device 10a aspirates the sample to be tested from the sample tube located at the sample aspiration position and discharges the sample into the reaction container to be loaded with the sample.

[0063] The sample dispensing device 10a includes a sample needle 101, a first needle moving mechanism 102, and a first power mechanism 103. The first needle moving mechanism 102 is configured to support the sample needle 101 and drive the sample needle 101 to move. For example, the sample needle 101 performs two-dimensional or three-dimensional movement in space through the two-dimensional or three-dimensional first needle moving mechanism 102, so that the sample needle 101 can move to aspirate the sample carried by the sample supply device 20.

[0064] The first power mechanism 103 is configured to aspirate the sample through the sample needle 101. For example, when the sample to be tested is a blood sample to be tested, the sample needle 101 moves under the drive of the first needle moving mechanism 102 into the sample tube containing the blood sample carried on the sample supply device 20, and aspirates the blood sample to be tested under the drive of the first power mechanism 103, and transports the blood sample to be tested into the reaction container at the reaction position in the reaction device 40. Thus, the blood sample to be tested aspirated by the dispensing device 10 is mixed with the reagent provided by the reagent supply device 20 in the reaction container.

[0065] As Figure 3 shown, in some embodiments, the first needle moving mechanism 102 includes a support frame 1021. The support frame 1021 is fixed on a support rod 1022. The support rod 1022 can move vertically and rotate. Driven by the support rod 1022, the support frame 1021 realizes vertical movement and horizontal rotation. The sample needle 101 is arranged on the support frame 1021 and can reach the target position under the drive of the support frame 1021. Exemplarily, the first needle moving mechanism 102 further includes a driver 1023 for driving the movement of the support rod 1022. For example, the driver is a stepper motor, but is not limited thereto. Optionally, the sample needle 101 is detachably or fixedly connected to the first needle moving mechanism 102.

[0066] Optionally, the first power mechanism 103 includes a pipeline 1031 and a power component 1033. The pipeline 1031 is used to transport a fluid medium. One end of the pipeline 1031 is connected to the pipetting needle 101, and the other end is connected to the power component 1033, so as to change the flow direction of the fluid medium in the pipeline 1031 under the action of the power component 1033, enabling the pipetting needle 101 to transfer samples and / or reagents. The power component 1033 includes, but is not limited to, a syringe and a pump.

[0067] In some embodiments, the dispensing device 10 further includes a reagent dispensing device 10b. The reagent supply device 30 includes a reagent carrying component 301 for carrying reagents. The reagent dispensing device 10b of the dispensing device 10 aspirates the reagents carried by the reagent supply device 30 and supplies them to the reaction device 40.

[0068] Optionally, the reagent carrying component 301 can be a reagent tray, which is arranged as a disc-shaped component and has a plurality of positions for carrying reagent containers. The reagent carrying component 301 can rotate and drive the reagent containers carried by it to rotate, so as to rotate the reagent containers to a specific position, such as the reagent aspiration position where the reagent is aspirated by the reagent dispensing device 10b. The number of the reagent carrying components 301 can be one or more.

[0069] In some embodiments, the reagent dispensing device 10b can include a reagent needle, a second needle moving mechanism, and a second power mechanism. The reagent needle moves in two or three dimensions in space through the two-dimensional or three-dimensional second needle moving mechanism, so that the reagent needle can move and cooperate with the second power mechanism to aspirate the reagents carried by the reagent carrying component 301, and move to the reaction container to be added with reagents and discharge the reagents into the reaction container.

[0070] In some embodiments, the second needle moving mechanism and the first needle moving mechanism 102 have the same structure, and / or the second power mechanism and the first power mechanism 103 have the same structure, which will not be elaborated here.

[0071] In some embodiments, the reagent dispensing device 10b does not add reagents by means of a reagent needle, but adds the reagents in the reagent tube to the reaction container through a dedicated pipeline. In such embodiments, there is only the sample needle 101 and no reagent needle.

[0072] It can be understood that, depending on the different body fluids to be detected and the different detection items, the sample and the reagent have different addition methods. For example, both the sample and the reagent can be added using the sample needle 101, or the sample is added using the sample needle 101 and the reagent is added using the reagent needle, or only the sample is added using the sample needle 101 and the reagent is added in other ways. That is, the sample dispensing device 10a of the dispensing device 10 is used for both transferring the sample and transferring the reagent; or the sample dispensing device 10a of the dispensing device 10 is used for sample transfer, and the reagent dispensing device 10b is used for reagent transfer; or the sample dispensing device 10a of the dispensing device 10 is used for sample transfer, and the reagent is connected to the reagent container carrying the reagent through a dedicated pipeline to add the reagent to the reaction container. Therefore, the sample needle 101 and / or the reagent needle are also called pipetting needles, that is, the pipetting needle includes at least any one of the sample needle 101 and the reagent needle.

[0073] In some embodiments, the sample analyzer 100 further includes at least one scheduling device (not shown in the figure). The scheduling device is used to perform scheduling operations. Specifically, the scheduling device can grasp or clamp the target object and drive the target object to move in a two-dimensional or three-dimensional space to achieve the scheduling of the target object. The target object includes, but is not limited to, the reaction container. For example, the scheduling device schedules the reaction container to a preset operation position (such as the sample addition position) inside the sample analyzer, so that after the sample dispensing device 10a completes the sample aspiration operation, it performs a sample addition operation on the reaction container placed at the sample addition position. Or, the scheduling device schedules the reaction container to the reagent addition position inside the sample analyzer, so that after the reagent dispensing device 10b completes the reagent aspiration operation, it performs a reagent addition operation on the reaction container placed at the reagent addition position.

[0074] It can be understood that the at least one scheduling device can include a first scheduling device and a second scheduling device. Different scheduling devices are used to perform different scheduling operations at different time nodes, or different scheduling devices are used to perform different scheduling operations at the same time node, which is not limited here.

[0075] In some embodiments, the sample analyzer 100 further includes a magnetic separation device 80, which is used to perform magnetic separation cleaning on the reaction solution to extract the magnetic particles enriched with the analyte in the reaction solution and clean the impurities attached to the surface of the magnetic particles, improve the purity of the analyte in the test sample, and further improve the accuracy of the sample detection result.

[0076] As Figure 1 shown, in some embodiments, the controller 70 can be one or more, and the controller 70 can be arranged on the analyzer execution body or can be arranged independently of the analyzer execution body, which is not limited here.

[0077] Optionally, the controller 70 at least includes a processor 701, a memory 702, a communication interface (not shown in the figure), and an I / O interface (not shown in the figure). The processor 701, the memory 702, the communication interface, and the I / O interface communicate via a bus. The processor 701 may be a Central Processing Unit (CPU), or the processor may also be other general-purpose processors, Digital Signal Processors (DSPs), Application Specific Integrated Circuits (ASICs), Field-Programmable Gate Arrays (FPGAs), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. Among them, the general-purpose processor may be a microprocessor or the processor may also be any conventional processor, etc.

[0078] The memory 702 stores various computer programs for the processor 701 to execute, such as an operating system and application programs, as well as data required to execute the computer programs. During the analysis of the sample to be tested, if there is data that needs to be locally stored, it can be stored in the memory 702. The I / O interface includes, but is not limited to, serial interfaces such as USB, IEEE1394, or RS-232C, parallel interfaces such as SCSI, IDE, or IEEE1284, and analog signal interfaces composed of D / A converters and converters, etc. An input component is connected to the I / O interface, and the user can directly input data to the controller 70 using the input component. The input component includes, but is not limited to, a keyboard, a mouse, a touch screen, or control buttons. The display component can be communicatively connected to the controller 70 through the I / O interface for relevant information prompting. The communication interface can be an interface of any currently known communication protocol. The communication interface communicates with the outside world through a network. The controller 70 can transmit data with any component connected through the network in a preset communication protocol through the communication interface.

[0079] In some embodiments, the controller 70 is at least used to, specifically, the processor 701 of the controller 70 calls the computer program in the memory 702 to implement the following method steps:

[0080] Control the analyzer to execute a first pretreatment operation on the sample. Among them, the first pretreatment operation includes: controlling the dispensing device 10 to add the sample and the first magnetic bead reagent to the first reaction vessel so that the sample and the first magnetic bead reagent are mixed to form a first mixed solution, and the first magnetic bead reagent is used to adsorb interfering substances in the sample; and controlling the magnetic adsorption device 50 to perform magnetic adsorption on the first mixed solution so that the first mixed solution is separated into a first magnetic bead particulate matter and a first test solution, and the first test solution contains the analyte;

[0081] After the first pretreatment operation is completed, the dispensing device 10 sucks the first test solution from the first reaction vessel and dispenses it into the second reaction vessel, and adds the first target reagent to the second reaction vessel to prepare the first target reaction solution.

[0082] The detection device 60 is controlled to detect the first target reaction solution to obtain the first detection data.

[0083] Please refer to Figure 4 , exemplarily, usually the sample contains the analyte and impurities, and the impurities usually affect the accuracy of the sample detection result. Therefore, they are also called interferents. In order to reduce the content of impurities in the sample and improve the accuracy of the sample detection, the controller 70 controls the analyzer main body to perform the first pretreatment operation on the sample. In this first pretreatment operation, the controller 70 controls the dispensing device 10 to add the test sample and the first magnetic bead reagent to the first reaction vessel, so that the sample and the first magnetic bead reagent are mixed in the first reaction vessel to form the first mixed solution. The test sample contains the effective analyte and the interferents that affect the detection of the analyte. The first magnetic bead reagent is used to adsorb the interferents in the sample. For example, the first magnetic bead reagent has the first magnetic bead particles, and the interferents in the sample can adhere to the surface of the first magnetic bead particles to form the corresponding first magnetic bead particles.

[0084] After the sample and the first magnetic bead reagent are mixed in the first reaction vessel to form the first mixed solution, the first mixed solution at this time contains at least the first magnetic bead particles and the first test solution, and the analyte in the sample remains in the first test solution. Based on the fact that the first magnetic bead particles can be magnetically adsorbed, in order to better separate the first magnetic bead particles and the first test solution, the magnetic adsorption device 50 is controlled to perform magnetic adsorption on the first mixed solution, so that the magnetic bead particles in the first mixed solution quickly precipitate under the magnetic adsorption of the magnetic adsorption device 50 and are separated to form the first magnetic bead particles and the first test solution.

[0085] After the magnetic adsorption device 50 performs magnetic adsorption on the first mixed solution in the first reaction vessel for a duration exceeding the preset duration, the first magnetic bead particles and the first test solution can be better separated. At this time, the controller 50 controls the dispensing device 10 to suck the first test solution from the first reaction vessel and dispense it into the second reaction vessel, and adds the first target reagent to the second reaction vessel to prepare the first target reaction solution. Furthermore, the detection device 60 can be used to detect the first target reaction solution to obtain the corresponding detection data.

[0086] Since the interferents in the sample adhere to the first magnetic bead reagent, the purity of the analyte in the obtained first test solution is relatively high. Therefore, effective purification of the analyte in the sample is achieved, and the concentration of interferents in the first target reaction solution prepared from the first test solution and the first target reagent is effectively reduced. Furthermore, by detecting the first target reaction solution, the accuracy of sample analysis can be effectively provided. Moreover, after the sample is pretreated by magnetic bead impurity removal, there is no need to dilute the sample multiple times, which can effectively improve the efficiency of sample detection.

[0087] It can be understood that the way the magnetic adsorption device 50 magnetically adsorbs the solution in the reaction vessel can be that the magnetic adsorption device moves to the position where the reaction vessel is located and magnetically adsorbs the solution in the reaction vessel.

[0088] Another way for the magnetic adsorption device 50 to magnetically adsorb the solution in the reaction vessel can be to dispatch the reaction vessel into the magnetic region formed when the magnetic adsorption device is working, so as to magnetically adsorb the solution in the reaction vessel within the magnetic region.

[0089] It can be understood that the way the dispensing device 10 dispenses the first target reagent and the first test solution into the second reaction vessel can be that the dispensing device 10 aspirates the first test solution from the first reaction vessel and adds it to the second reaction vessel, and then adds the first target reagent to the second reaction vessel containing the first test solution, so that the first test solution and the first target reagent are mixed to form the first target reaction solution, as Figure 4 shown.

[0090] The way the dispensing device 10 dispenses the first target reagent and the first test solution into the second reaction vessel can be that the dispensing device 10 adds the first target reagent to the second reaction vessel, and then aspirates the first test solution from the first reaction vessel and discharges the first test solution into the second reaction vessel containing the first target reagent, so that the first test solution and the first target reagent are mixed to form the first target reaction solution.

[0091] The way the dispensing device 10 dispenses the first target reagent and the first test solution into the second reaction vessel can be that the dispensing device 10 adds a part of the first target reagent to the second reaction vessel, and then aspirates the first test solution from the first reaction vessel and discharges the first test solution into the second reaction vessel containing the first target reagent. After the first test solution is added, another part of the first target reagent is added to the second reaction vessel, so that the first test solution and the first target reagent are mixed to form the first target reaction solution.

[0092] It can be understood that when the dispensing device 10 dispenses reagents or waste liquids, it is executed by the reagent dispensing device 10b of the dispensing device 10. When the dispensing device 10 dispenses samples or test liquids to be measured, it is executed by the sample dispensing device 10a of the dispensing device 10. Alternatively, the dispensing device 10 executes the dispensing of samples, reagents, and waste liquids through either the reagent dispensing device 10b or the sample dispensing device 10a, which is not limited herein.

[0093] In some embodiments, the controller 70 is further configured to: during the process of the dispensing device 10 sucking the first test liquid to be measured from the first reaction vessel, control the magnetic adsorption device 50 to magnetically adsorb the solution in the first reaction vessel, so as to effectively reduce the probability of the first magnetic bead particles in the first reaction vessel being transferred during the process of the dispensing device 10 sucking the first test liquid to be measured, thereby improving the purity of the analyte in the transferred first test liquid to be measured.

[0094] In some embodiments, the sample analyzer 100 is provided with a first detection process and a second detection process for detecting samples. When the sample analyzer 100 uses the first detection process to detect samples, the controller 70 executes:

[0095] Control the analyzer execution body to perform a first pre-treatment operation on the sample;

[0096] After the first pre-treatment operation is completed, control the dispensing device 10 to suck the first test liquid to be measured from the first reaction vessel and dispense it into the second reaction vessel, and add a first target reagent to the second reaction vessel to prepare a first target reaction solution;

[0097] Control the detection device 60 to detect the first target reaction solution to obtain first detection data;

[0098] When the sample analyzer uses the second detection process to detect samples, the controller 70 executes:

[0099] Control the dispensing device 10 to add the sample and a second target reagent to the reaction vessel to mix the sample and the second target reagent to form a second target reaction solution; and control the detection device 60 to detect the second target reaction solution to obtain second detection data.

[0100] Exemplarily, the sample analyzer 100 is provided with at least two detection processes, and the at least two detection processes include a first detection process and a second detection process. For different sample detection requirements, an adapted detection process can be used to detect the samples to effectively improve the accuracy of sample detection.

[0101] For example, when the content of interfering substances in the sample is relatively high, the first detection process can be used to detect the sample to remove impurities from the sample through the pre-treatment operation of the sample, thereby improving the accuracy of sample detection.

[0102] When the content of the interfering substance in the sample is within a controllable range, the second detection process can be used to detect the sample to improve the efficiency of sample detection.

[0103] In some embodiments, the analyzer execution body further includes an input device, and the controller 70 is further configured to:

[0104] Obtain the input information of the input device, and control the analyzer execution body to detect the sample using the first detection process or the second detection process according to the input information.

[0105] Exemplarily, the input device includes but is not limited to a mouse, a keyboard, a button, a touch panel, a voice collection device, a gesture collection device, etc. An operator can use the input device to input corresponding input information to the sample analyzer 100, and the controller 70 determines to use the first detection process or the second detection process to detect the sample according to the information input by the input device.

[0106] It can be understood that the input information includes but is not limited to the detection item information of the sample, the detection process selection instruction, the detection item code of the sample, the sample type, etc.

[0107] For example, when it is indicated in the input information that the first detection process is used to detect the sample, the controller 70 controls the analyzer execution body to detect the sample using the first detection process. Or, when the controller 70 analyzes from the input information that the current sample needs to be detected using the first detection process, the controller 70 controls the analyzer execution body to detect the sample using the first detection process.

[0108] In some embodiments, the analyzer execution body further includes a scanning device, the sample is carried in a sample container, and the controller 70 is further configured to:

[0109] Control the scanning device to scan the barcode information set on the sample container, and obtain the detection item information corresponding to the sample according to the scanning result of the barcode information;

[0110] When the detection item information is preset detection item information, the first detection process is used to detect the sample;

[0111] When the detection item information is non-preset detection item information, the second detection process is used to detect the sample.

[0112] Exemplarily, the barcode information includes, but is not limited to, two-dimensional codes, barcodes, and RFID. The sample analyzer 100 stores the association relationship between the detection item information and the target detection process. The target detection process includes a first detection process and a second detection process. After determining the detection item information corresponding to the current sample, the controller can determine to use the first detection process or the second detection process to detect the sample according to the detection item information.

[0113] In some embodiments, the analyzer execution body further includes an image processing device, and the controller 70 is further configured to:

[0114] Control the image processing device to collect a sample image of the sample and obtain the interference information in the sample;

[0115] Detect the sample using the first detection process or the second detection process according to the interference information.

[0116] Exemplarily, the image processing device includes an image acquisition component and an image analysis component. The sample image of the sample is collected by the image acquisition component, and the sample image is analyzed by the image analysis component to obtain the interference information in the sample. The sample analyzer 100 is provided with the association relationship between the interference information and the target detection process. After obtaining the interference information in the sample, it is possible to determine that the current sample needs to be detected by the first detection process or the second detection process according to the interference information.

[0117] In some embodiments, the controller 70 is further configured to: obtain the detection item information corresponding to the sample, control the dispensing device 10 to dispense the sample and the second target reagent into the reaction container so that the sample and the second target reagent are mixed to form a second target reaction solution; and control the detection device 60 to detect the second target reaction solution to obtain second detection data;

[0118] When it is determined according to the second detection data that the sample needs to be retested, control the analyzer execution body to perform a first pretreatment operation on the sample;

[0119] After the first pretreatment operation is completed, control the dispensing device 10 to aspirate the first test solution from the first reaction container and dispense it into the second reaction container, and add the first target reagent to the second reaction container to prepare a first target reaction solution;

[0120] Control the detection device 60 to detect the first target reaction solution to obtain first detection data and output a detection result according to the first detection data;

[0121] When it is determined according to the project detection data that the sample does not need to be retested, output a detection result according to the second detection data.

[0122] Exemplarily, during the detection of a sample, the detection item information of the sample can be obtained first, and the second target reagent required for the detection of the sample can be determined according to the detection item information. Then, the dispensing device 10 is controlled to dispense the sample and the second target reagent into the reaction container, so that the sample and the second target reagent are mixed in the reaction container to form a second target reaction solution. Then, the second target reaction solution is detected by the detection device 60 to obtain corresponding second detection data. By analyzing the second detection data, it can be determined whether the currently obtained second detection data meets the preset requirements. For example, by analyzing the second detection data, it can be known whether there is a preset abnormal type in the current second detection data (such as the sample may contain a certain type of interferent).

[0123] When the second detection data meets the preset requirements, it indicates that there is no abnormality in the current sample detection, and then the detection result corresponding to the sample is output based on the second detection data.

[0124] When there is a preset abnormal type in the second detection data, it indicates that there may be a problem with the excessive interference concentration in the current sample, and then the sample needs to be retested. During the retesting process, the controller 70 controls the analyzer main body to perform a first pretreatment operation on the sample, so as to reduce the concentration of interferents in the sample. After the first pretreatment operation is completed, the dispensing device 10 is controlled to aspirate the first test solution from the first reaction container and dispense it into the second reaction container, and the first target reagent is added to the second reaction container to prepare a first target reaction solution; the detection device 60 is controlled to detect the first target reaction solution, obtain the first detection data and output the detection result based on the first detection data, so that the output detection result is more accurate and reliable.

[0125] In some embodiments, the analyzer main body further includes a first scheduling device and a second scheduling device. When the controller 70 controls the magnetic adsorption device 50 to perform magnetic adsorption on the first mixed solution, it includes:

[0126] Controlling the first scheduling device to schedule the first reaction container carrying the first mixed solution to the carrying position on the second scheduling device, and controlling the second scheduling device to schedule the first reaction container to the aspiration position where the dispensing device 10 aspirates the first test solution; wherein, during the process of the second scheduling device scheduling the first reaction container to the aspiration position, the magnetic adsorption device 50 is controlled to perform magnetic adsorption on the first mixed solution in the first reaction container located at the carrying position.

[0127] By arranging the magnetic adsorption device 50 on the carrying position of the corresponding scheduling device, the solution in the reaction container can be magnetically adsorbed during the scheduling process of the reaction container, and the magnetic adsorption of the solution in the reaction container can be reused during the scheduling cycle, so that there is no need to set an independent cycle for magnetic adsorption, which can effectively save the sample detection cycle.

[0128] In some embodiments, the analyzer execution body performs a detection operation on a sample during a sample detection cycle, and the sample detection cycle includes at least a dispensing action cycle and a detection action cycle;

[0129] The controller 70 is configured to: during the dispensing action cycle, control the dispensing device 10 to perform sample dispensing and reagent dispensing into corresponding reaction vessels, and during the detection action cycle, control the detection device 60 to detect the reaction solution;

[0130] The controller 70 is further configured to insert a first sample pretreatment cycle before the analyzer execution body performs the dispensing action cycle, before controlling the analyzer execution body to perform the first pretreatment operation on the sample;

[0131] During the first sample pretreatment cycle, the controller 70 controls the analyzer execution body to perform the first pretreatment operation on the sample.

[0132] Optionally, the first cycle duration corresponding to the first sample pretreatment cycle is an integer multiple of the second cycle duration corresponding to the dispensing action cycle.

[0133] Exemplarily, when the sample needs to be pretreated, the controller 70 inserts a corresponding sample pretreatment cycle before the normal sample cycle, so as to perform the corresponding sample pretreatment operation during the sample pretreatment cycle, and thus there is no need to perform the corresponding sample pretreatment operation during other adjacent normal sample detection cycles, so that the first pretreatment operation does not affect the normal operation of other sample detection cycles.

[0134] In some embodiments, during the process of the execution body performing the same detection item on the sample, the first detection process has a first calibration coefficient, and the second detection process has a second calibration coefficient different from the first calibration coefficient; wherein, after the controller 70 controls the detection device 60 to detect the first target reaction solution and obtains the first detection data, it performs: obtaining the first detection result of the sample according to the first detection data and the first calibration coefficient, and outputting the first detection result;

[0135] After the controller 70 controls the detection device 60 to detect the second target reaction solution and obtains the second detection data, it performs: obtaining the second detection result of the sample according to the second detection data and the second calibration coefficient, and outputting the second detection result.

[0136] Exemplarily, in the same detection item, the concentrations of the reaction solutions prepared by different detection processes are different. Therefore, in order to obtain more accurate detection results, different calibration coefficients need to be set according to different detection processes. After obtaining the corresponding detection data by detecting the reaction solution through the detection device 60, the detection result of the sample is obtained according to the detection data and the corresponding matching calibration coefficient to ensure the accuracy of the detection result.

[0137] For example, after the sample undergoes the first pretreatment operation, a first test solution is obtained by adding a first magnetic bead reagent to the sample for pretreatment. The concentration of the first test solution has changed relative to the concentration of the initial sample. Therefore, after the reaction solution is detected by the detection device 60 to obtain corresponding detection data, the detection data is calibrated using a preset calibration coefficient to make the obtained detection result more accurate.

[0138] Optionally, the second calibration coefficient is 1, that is, the second detection data is not calibrated to obtain the second detection result.

[0139] Please refer to Figures 5 to 6 , in some embodiments, the controller 70 is at least used for: controlling the analyzer execution body to perform a second pretreatment operation on the sample. Among them, the second pretreatment operation includes: controlling the analyzer execution body to dispense the sample and a second magnetic bead reagent into a third reaction container to mix the sample and the second magnetic bead reagent to form a second mixed solution, and the second magnetic bead reagent is used to adsorb the analyte in the sample; controlling the analyzer execution body to perform magnetic adsorption on the second mixed solution to separate the second mixed solution into a second magnetic bead particulate matter and a second liquid, and controlling the analyzer execution body to aspirate the second liquid in the third reaction container; controlling the analyzer execution body to dispense a displacement reagent into the third reaction container carrying the second magnetic bead particulate matter to mix the displacement reagent and the second magnetic bead particulate matter to form a third mixed solution, and the displacement reagent is used to displace the analyte from the second magnetic bead particulate matter; controlling the analyzer execution body to perform magnetic adsorption on the third mixed solution to separate the third mixed solution into a third magnetic bead particulate matter and a second test solution, and the second test solution contains the analyte;

[0140] After the second pretreatment operation is completed, controlling the analyzer execution body to aspirate the second test solution and dispense it into a fourth reaction container, and dispensing a third target reagent into the fourth reaction container to prepare a third target reaction solution;

[0141] Controlling the analyzer execution body to detect the third target reaction solution to obtain third detection data.

[0142] As Figure 5 shown, exemplarily, in order to reduce the content of impurities in the sample and improve the accuracy of sample detection, the controller 70 controls the analyzer execution body to perform a second pretreatment operation on the sample. In this second pretreatment operation, the controller 70 controls the dispensing device 10 to add the test sample and the second magnetic bead reagent to the third reaction container to mix the sample and the second magnetic bead reagent in the third reaction container to form a second mixed solution. The test sample contains effective analytes and interfering substances that affect the detection of analytes. The second magnetic bead reagent is used to adsorb the analytes in the sample. For example, the second magnetic bead reagent has second magnetic beads, and the analytes in the sample can adhere to the surface of the second magnetic beads to form corresponding second magnetic bead particulate matters.

[0143] After the sample and the second magnetic bead reagent are mixed in the third reaction vessel to form a second mixed solution, the second mixed solution at this time contains at least second magnetic bead particles and a second liquid. Most of the analytes in the sample adhere to the second magnetic bead particles. The second liquid is waste liquid. After the analytes adhere to the second magnetic bead particles, most of the interfering substances in the sample are left in the second liquid. Based on the fact that the second magnetic bead particles can be magnetically adsorbed, in order to better separate the second magnetic bead particles and the second liquid, the magnetic adsorption device 50 is controlled to perform magnetic adsorption on the second mixed solution, so that the magnetic bead particles in the second mixed solution quickly precipitate under the magnetic adsorption of the magnetic adsorption device 50 and are separated to form second magnetic bead particles and a second liquid.

[0144] After the magnetic adsorption device 50 performs magnetic adsorption on the second mixed solution in the third reaction vessel for a duration exceeding the preset duration, the second magnetic bead particles and the second liquid can be better separated. At this time, the controller 50 controls the dispensing device 10 to aspirate the second liquid from the third reaction vessel and discharge it into a preset waste liquid treatment container, so that the second magnetic bead particles are retained in the third reaction vessel.

[0145] After completing the second liquid aspiration operation, the dispensing device 10 is controlled to dispense a replacement reagent into the third reaction vessel carrying the second magnetic bead particles, so that the replacement reagent and the second magnetic bead particles are mixed to form a third mixed solution. The replacement reagent is used to displace the analytes from the second magnetic bead particles, so that the analytes are remixed in the solution.

[0146] As Figure 6 shown, after the dispensing device 10 dispenses a replacement reagent into the third reaction vessel carrying the second magnetic bead particles to form a third mixed solution, the third mixed solution at this time contains at least third magnetic bead particles and a second analyte solution. The second analyte solution contains analytes. Based on the fact that the third magnetic bead particles can be magnetically adsorbed, in order to better separate the third magnetic bead particles and the second analyte solution, the magnetic adsorption device 50 is controlled to perform magnetic adsorption on the third mixed solution, so that the magnetic bead particles in the third mixed solution quickly precipitate under the magnetic adsorption of the magnetic adsorption device 50 and are separated to form third magnetic bead particles and a second analyte solution.

[0147] After the magnetic adsorption device 50 performs magnetic adsorption on the third mixed solution in the third reaction vessel for a duration exceeding the preset duration, the third magnetic bead particles and the second analyte solution can be better separated. At this time, the controller 50 controls the dispensing device 10 to aspirate the second analyte solution from the third reaction vessel and dispense it into the fourth reaction vessel, and adds a third target reagent to the fourth reaction vessel to prepare a third target reaction solution, and then the detection device 60 can detect the third target reaction solution to obtain corresponding detection data.

[0148] Based on the analyte in the sample adhering to the second magnetic bead reagent, the second mixed solution is separated by magnetic adsorption to form second magnetic bead particles and a second liquid. At this time, the second liquid is aspirated, and a displacement reagent is added to the third reaction container carrying the second magnetic bead particles, so as to displace the analyte adhering to the second magnetic bead particles into the solution to form a second test solution, thereby completing the impurity removal pretreatment of the sample. After completing the sample pretreatment, the dispensing device aspirates the second test solution containing the analyte in the third reaction container and distributes the second test solution to the fourth reaction container, and a third target reagent is dispensed into the fourth reaction container, so that the second test solution containing the analyte and the third target reagent are mixed to form a third target reaction solution. Based on the impurity removal pretreatment of the sample, the concentration of impurities in the sample can be effectively reduced, so that it is not necessary to dilute the sample multiple times, effectively improving the efficiency of sample detection. And after the impurity removal pretreatment, the concentration of impurities in the third target reaction solution formed by mixing the second test solution and the third target reagent can be effectively reduced. Furthermore, by detecting the third target reaction solution, the accuracy of sample analysis can be effectively provided.

[0149] Optionally, after the dispensing device 10 dispenses the displacement reagent to the third reaction container carrying the second magnetic bead particles, the mixing device is controlled to mix the solution in the third reaction container so that the displacement reagent and the second magnetic bead particles are fully mixed to form a third mixed solution.

[0150] It can be understood that the way the dispensing device 10 dispenses the third target reagent and the second test solution to the fourth reaction container can be that the dispensing device 10 aspirates the second test solution from the third reaction container and injects it into the fourth reaction container, and then injects the third target reagent into the fourth reaction container carrying the second test solution, so that the second test solution and the third target reagent are mixed to form a third target reaction solution, as Figure 5 shown.

[0151] Another way for the dispensing device 10 to dispense the third target reagent and the second test solution to the fourth reaction container can be that the dispensing device 10 injects the third target reagent into the fourth reaction container, and then aspirates the second test solution from the third reaction container and discharges the second test solution into the fourth reaction container carrying the third target reagent, so that the second test solution and the third target reagent are mixed to form a third target reaction solution.

[0152] Another way for the dispensing device 10 to dispense the third target reagent and the second test solution to the fourth reaction container can be that the dispensing device 10 injects a part of the third target reagent into the fourth reaction container, and then aspirates the second test solution from the third reaction container and discharges the second test solution into the fourth reaction container carrying the third target reagent. After the injection of the second test solution is completed, another part of the third target reagent is injected into the fourth reaction container, so that the second test solution and the third target reagent are mixed to form a third target reaction solution.

[0153] It can be understood that in some embodiments, the analyzer execution body includes a waste liquid suction device, and when sucking the second liquid in the third reaction container, it is sucked through the waste liquid suction device.

[0154] Optionally, the controller 70 is further configured to: during the process of the dispensing device 10 sucking the second liquid from the third reaction container, control the magnetic adsorption device 50 to magnetically adsorb the solution in the third reaction container, so as to effectively reduce the probability that the magnetic bead particles in the third reaction container are transferred during the process of the dispensing device 10 sucking the second liquid, so that more analytes are retained in the third reaction container.

[0155] Optionally, the controller 70 is further configured to: during the process of the dispensing device 10 sucking the second test solution from the third reaction container, control the magnetic adsorption device 50 to magnetically adsorb the solution in the third reaction container, so as to effectively reduce the probability that the magnetic bead particles in the third reaction container are transferred during the process of the dispensing device 10 sucking the second test solution, thereby improving the purity of the analytes in the transferred first test solution.

[0156] In some embodiments, the analyzer execution body further includes a substrate dispensing device (not shown in the figure) and a magnetic separation device 80, and the third target reagent includes a third magnetic bead reagent and an enzyme-labeled reagent; when the controller 70 controls the analyzer execution body to dispense the third target reagent into the fourth reaction container to prepare the third target reaction solution, it performs:

[0157] Control the dispensing device 10 to dispense the third magnetic bead reagent and the enzyme-labeled reagent into the fourth reaction container carrying the second test solution, so that the sample, the third magnetic bead reagent and the enzyme-labeled reagent are mixed to form an initial reaction solution;

[0158] Control the magnetic separation device 70 to perform magnetic separation cleaning on the initial reaction solution to clean the impurities in the initial reaction solution;

[0159] After the magnetic separation cleaning is completed, control the substrate dispensing device to add the substrate to the fourth reaction container to prepare and form the third target reaction solution.

[0160] Exemplarily, the device used for the cleaning and separation technology in the present application is the magnetic separation device 80. By performing magnetic separation on the reaction solution through the magnetic separation device 80, the effective components in the reaction solution, that is, the analytes, can be extracted.

[0161] The sample in the reaction vessel is mixed with the target reagent to form a reaction solution. The reaction device 40 can incubate the reaction solution in the reaction vessel, enabling the residual sample and the target reagent in the reaction solution to react fully. At this time, the reaction solution in the reaction vessel includes the analyte and impurities. The incubated reaction solution presents in the reaction vessel in the form of the analyte and impurities. The impurities can be substances that have not reacted fully, by-products generated from side reactions, or other substances that affect the detection of the detection device, etc., or a combination of at least two of the above. The magnetic separation device 80 cleans the analyte and impurities in the reaction vessel to remove the impurities in the reaction vessel and retain the analyte in the reaction vessel. The detection device 60 can detect the analyte in the reaction vessel to obtain various parameters of the sample. If a substrate is added to the reaction vessel after separation and cleaning, at this time, the reaction solution in the reaction vessel is a reaction solution formed by mixing the substrate and the analyte. Since the substrate does not change the properties of the analyte but only increases the luminescence value of the analyte, the solution formed by mixing the substrate and the analyte is still a reaction solution.

[0162] In some embodiments, the analyzer execution body is provided with a third detection process and a second detection process for detecting the sample. When the analyzer execution body uses the third detection process to detect the sample, the controller 70 executes:

[0163] Control the analyzer execution body to perform a second pretreatment operation on the sample;

[0164] After the second pretreatment operation is completed, control the analyzer execution body to aspirate the second test solution and dispense it into the fourth reaction vessel, and add a third target reagent to the fourth reaction vessel to prepare a third target reaction solution; control the detection device 60 to detect the third target reaction solution to obtain third detection data;

[0165] When using the second detection process to detect the sample, the controller 70 executes:

[0166] Control the dispensing device 10 to add the sample and the second target reagent to the reaction vessel so that the sample and the second target reagent are mixed to form a second target reaction solution; and control the detection device 60 to detect the second target reaction solution to obtain second detection data.

[0167] Exemplarily, the sample analyzer 100 is provided with at least two detection processes, and the at least two detection processes include a third detection process and a second detection process. For different sample detection requirements, an appropriate detection process can be used to detect the sample to effectively improve the accuracy of sample detection.

[0168] For example, when the content of interfering substances in the sample is relatively high, the third detection process can be used to detect the sample to remove impurities from the sample through a pretreatment operation on the sample and improve the accuracy of sample detection.

[0169] When the content of the interfering substance in the sample is within a controllable range, the second detection process can be adopted to detect the sample, so as to improve the efficiency of sample detection.

[0170] In some embodiments, the analyzer execution body further includes an input device, and the controller 70 is further configured to:

[0171] Obtain the input information of the input device, and control the analyzer execution body to detect the sample by adopting the third detection process or the second detection process according to the input information.

[0172] In some embodiments, the analyzer execution body further includes a scanning device, the sample is carried on a sample container, and the controller 70 is further configured to:

[0173] Control the scanning device to scan the barcode information set on the sample container, and obtain the detection item information corresponding to the sample according to the scanning result of the barcode information;

[0174] When the detection item information is preset detection item information, the third detection process is adopted to detect the sample;

[0175] When the detection item information is non-preset detection item information, the second detection process is adopted to detect the sample.

[0176] In some embodiments, the analyzer execution body further includes an image processing device, and the controller 70 is further configured to:

[0177] Control the image processing device to collect the sample image of the sample, and obtain the interfering substance information in the sample;

[0178] Detect the sample by adopting the third detection process or the second detection process according to the interfering substance information.

[0179] In some embodiments, the controller 70 is further configured to: obtain the detection item information corresponding to the sample, control the dispensing device 10 to dispense the sample and the second target reagent into the reaction container, so that the sample and the second target reagent are mixed to form a second target reaction solution; and control the detection device 60 to detect the second target reaction solution to obtain second detection data;

[0180] When it is determined according to the second detection data that the sample needs to be retested, control the analyzer execution body to perform a second pretreatment operation on the sample;

[0181] After the second pretreatment operation is completed, control the dispensing device 10 to suck the second test solution from the third reaction container and dispense it into the fourth reaction container, and add the third target reagent to the fourth reaction container to prepare a third target reaction solution;

[0182] The control detection device 60 detects the third target reaction liquid, obtains the third detection data, and outputs a detection result according to the third detection data;

[0183] When it is determined according to the project detection data that there is no need to perform a re-examination on the sample, a detection result is output according to the second detection data.

[0184] In some embodiments, the analyzer execution body further includes a first scheduling device and a second scheduling device. When the controller controls the magnetic adsorption device to magnetically adsorb the third mixed liquid, it includes:

[0185] Controlling the first scheduling device to schedule the third reaction vessel carrying the third mixed liquid to the carrying position on the second scheduling device, and controlling the second scheduling device to schedule the third reaction vessel to the liquid suction position where the dispensing device 10 sucks the second liquid to be detected;

[0186] Wherein, during the process of the second scheduling device scheduling the third reaction vessel to the liquid suction position, the magnetic adsorption device is controlled to magnetically adsorb the third mixed liquid in the third reaction vessel located at the carrying position.

[0187] In some embodiments, the analyzer execution body further includes a first scheduling device and a second scheduling device. When the controller controls the magnetic adsorption device to magnetically adsorb the second mixed liquid, it includes:

[0188] Controlling the first scheduling device to schedule the third reaction vessel carrying the second mixed liquid to the carrying position on the second scheduling device, and controlling the second scheduling device to schedule the third reaction vessel to the liquid suction position where the dispensing device 10 sucks the second liquid;

[0189] Wherein, during the process of the second scheduling device scheduling the third reaction vessel to the liquid suction position, the magnetic adsorption device is controlled to magnetically adsorb the second mixed liquid in the third reaction vessel located at the carrying position.

[0190] In some embodiments, the analyzer execution body performs a detection operation on the sample within the sample detection period, and the sample detection period at least includes a dispensing action period and a detection action period;

[0191] The controller 70 is configured to: within the dispensing action period, control the dispensing device 10 to perform sample dispensing and reagent dispensing to the corresponding reaction vessels, and within the detection action period, control the detection device 60 to detect the reaction liquid;

[0192] The controller 70 is further configured to insert a second sample pretreatment period before the analyzer execution body performs the third pretreatment operation on the sample and before the analyzer execution body performs the dispensing action period; during the second sample pretreatment period, the controller controls the analyzer execution body to perform the third pretreatment operation on the sample.

[0193] Optionally, the first cycle duration corresponding to the second sample preprocessing cycle is an integer multiple of the second cycle duration corresponding to the dispensing operation cycle.

[0194] In some embodiments, during the process of the execution subject performing the same detection item on the sample, the third detection process has a third calibration coefficient, and the second detection process has a second calibration coefficient different from the third calibration coefficient;

[0195] Wherein, after the controller controls the detection device to detect the third target reaction solution and obtains the third detection data, it performs: obtaining the third detection result of the sample according to the third detection data and the third calibration coefficient, and outputting the third detection result;

[0196] After the controller controls the detection device to detect the second target reaction solution and obtains the second detection data, it performs: obtaining the second detection result of the sample according to the second detection data and the second calibration coefficient, and outputting the second detection result.

[0197] The sample analysis method provided by the embodiments of the present application will be described below in conjunction with the working principle of the sample analyzer 100.

[0198] The embodiments of the present application further provide a sample analysis method, which is applied to the aforementioned sample analyzer 100. This analyzer includes an analyzer execution subject, and the method includes:

[0199] Controlling the analyzer execution subject to perform a first preprocessing operation on the sample. Among them, the first preprocessing operation includes: controlling the dispensing device 10 of the analyzer execution subject to add the sample and the first magnetic bead reagent to the first reaction container, so that the sample and the first magnetic bead reagent are mixed to form a first mixed solution. The first magnetic bead reagent is used to adsorb interfering substances in the sample; and controlling the magnetic adsorption device 50 of the analyzer execution subject to perform magnetic adsorption on the first mixed solution, so that the first mixed solution is separated to form a first magnetic bead particulate matter and a first test solution, and the first test solution contains the analyte;

[0200] After the first preprocessing operation is completed, controlling the dispensing device 10 to aspirate the first test solution from the first reaction container and dispense it into the second reaction container, and adding the first target reagent to the second reaction container to prepare the first target reaction solution;

[0201] Controlling the detection device 60 of the analyzer execution subject to detect the first target reaction solution and output the first detection result.

[0202] In some embodiments, the sample analyzer is provided with a first detection process and a second detection process for detecting the sample. When using the first detection process to detect the sample, it includes:

[0203] Control the analyzer execution body to perform the first pretreatment operation on the sample;

[0204] After the first pretreatment operation is completed, control the dispensing device to aspirate the first test solution from the first reaction container and dispense it into the second reaction container, and add a first target reagent to the second reaction container to prepare a first target reaction solution;

[0205] Control the detection device to detect the first target reaction solution to obtain first detection data;

[0206] When the sample analyzer uses the second detection process to detect the sample, the controller performs:

[0207] Control the dispensing device to add the sample and a second target reagent to the reaction container so that the sample and the second target reagent are mixed to form a second target reaction solution; and control the detection device to detect the second target reaction solution to obtain second detection data.

[0208] In some embodiments, the analyzer execution body further includes an input device, and the method further includes:

[0209] Obtain the input information of the input device, and control the analyzer execution body to use the first detection process or the second detection process to detect the sample according to the input information.

[0210] In some embodiments, the analyzer execution body further includes a scanning device, the sample is carried in a sample container, and the method further includes:

[0211] Control the scanning device to scan the barcode information set on the sample container, and obtain the detection item information corresponding to the sample according to the scanning result of the barcode information;

[0212] When the detection item information is preset detection item information, use the first detection process to detect the sample;

[0213] When the detection item information is non-preset detection item information, use the second detection process to detect the sample.

[0214] In some embodiments, the analyzer execution body further includes an image processing device, and the method further includes:

[0215] Control the image processing device to collect a sample image of the sample and obtain interference information in the sample;

[0216] Detect the sample using the first detection process or the second detection process according to the interference information.

[0217] In some embodiments, the method further includes:

[0218] Obtaining the detection item information corresponding to the sample, controlling the aliquoting device to aliquot the sample and the second target reagent into the reaction vessel so that the sample and the second target reagent are mixed to form a second target reaction solution; and controlling the detection device to detect the second target reaction solution to obtain second detection data;

[0219] When it is determined according to the second detection data that the sample needs to be re - examined, controlling the analyzer execution body to perform the first pretreatment operation on the sample;

[0220] After the first pretreatment operation is completed, controlling the aliquoting device to aspirate the first test solution from the first reaction vessel and aliquot it into the second reaction vessel, and adding the first target reagent to the second reaction vessel to prepare a first target reaction solution;

[0221] Controlling the detection device to detect the first target reaction solution to obtain first detection data and output a detection result according to the first detection data;

[0222] When it is determined according to the item detection data that the sample does not need to be re - examined, outputting a detection result according to the second detection data.

[0223] In some embodiments, the method further includes: during the process of the aliquoting device aspirating the first test solution from the first reaction vessel, controlling the magnetic adsorption device to perform magnetic adsorption on the solution in the first reaction vessel.

[0224] In some embodiments, the analyzer execution body further includes a first scheduling device and a second scheduling device. During the process of controlling the magnetic adsorption device to perform magnetic adsorption on the first mixed solution, it includes:

[0225] Controlling the first scheduling device to schedule the first reaction vessel carrying the first mixed solution to the carrying position on the second scheduling device, and controlling the second scheduling device to schedule the first reaction vessel to the aspiration position where the aliquoting device aspirates the first test solution;

[0226] Wherein, during the process of the second scheduling device scheduling the first reaction vessel to the aspiration position, controlling the magnetic adsorption device to perform magnetic adsorption on the first mixed solution in the first reaction vessel located at the carrying position.

[0227] In some embodiments, the analyzer execution body performs a detection operation on a sample within a sample detection cycle, and the sample detection cycle includes at least an aliquoting action cycle and a detection action cycle;

[0228] The method includes: during the dispensing action cycle, controlling the dispensing device to perform sample dispensing and reagent dispensing into corresponding reaction vessels, and during the detection action cycle, controlling the detection device to detect the reaction solution;

[0229] The method further includes: before controlling the analyzer execution body to perform a first pretreatment operation on the sample, inserting a sample pretreatment cycle before the analyzer execution body executes the dispensing action cycle;

[0230] During the sample pretreatment cycle, the controller controls the analyzer execution body to perform the first pretreatment operation on the sample.

[0231] In some embodiments, a first cycle duration corresponding to the sample pretreatment cycle is an integer multiple of a second cycle duration corresponding to the dispensing action cycle.

[0232] In some embodiments, during the process of the execution body performing the same detection item on the sample, the first detection process has a first calibration coefficient, and the second detection process has a second calibration coefficient different from the first calibration coefficient;

[0233] Wherein, after controlling the detection device to detect the first target reaction solution to obtain first detection data, the method further includes:

[0234] Obtaining a first detection result of the sample according to the first detection data and the first calibration coefficient, and outputting the first detection result;

[0235] After controlling the detection device to detect the second target reaction solution to obtain second detection data, the method further includes:

[0236] Obtaining a second detection result of the sample according to the second detection data and the second calibration coefficient, and outputting the second detection result.

[0237] It should be noted that those skilled in the art can clearly understand that for the convenience and brevity of description, the specific working process of the above-described sample analysis method can refer to the corresponding working process of the foregoing sample analyzer, and will not be elaborated herein.

[0238] An embodiment of the present application further provides a sample analysis method, which is applied to the foregoing sample analyzer 100. This analyzer includes an analyzer execution body, and the method includes:

[0239] The analyzer execution body of the sample analyzer performs a second pretreatment operation on the sample. The second pretreatment operation includes: controlling the analyzer execution body to dispense the sample and a second magnetic bead reagent into a third reaction container so that the sample and the second magnetic bead reagent are mixed to form a second mixed solution, and the second magnetic bead reagent is used to adsorb the analyte in the sample; controlling the analyzer execution body to perform magnetic adsorption on the second mixed solution so that the second mixed solution is separated to form second magnetic bead particles and a second liquid, and controlling the analyzer execution body to aspirate the second liquid in the third reaction container; controlling the analyzer execution body to dispense a replacement reagent into the third reaction container carrying the second magnetic bead particles so that the replacement reagent and the second magnetic bead particles are mixed to form a third mixed solution, and the replacement reagent is used to displace the analyte from the second magnetic bead particles; controlling the analyzer execution body to perform magnetic adsorption on the third mixed solution so that the third mixed solution is separated to form third magnetic bead particles and a second analyte solution, and the second analyte solution contains the analyte;

[0240] After the second pretreatment operation is completed, control the analyzer execution body to aspirate the second analyte solution from the third reaction container and dispense it into a fourth reaction container, and dispense a third target reagent into the fourth reaction container to prepare a third target reaction solution;

[0241] Control the analyzer execution body to detect the third target reaction solution to obtain third detection data.

[0242] In some embodiments, the sample analyzer is provided with a third detection process and a second detection process for detecting the sample. When using the third detection process to detect the sample, it includes:

[0243] Control the analyzer execution body to perform the second pretreatment operation on the sample;

[0244] After the second pretreatment operation is completed, control the dispensing device to aspirate the second analyte solution from the third reaction container and dispense it into a fourth reaction container, and add a third target reagent to the fourth reaction container to prepare a third target reaction solution;

[0245] Control the detection device to detect the third target reaction solution to obtain third detection data;

[0246] When the sample analyzer uses the second detection process to detect the sample, the controller performs:

[0247] Control the dispensing device to add the sample and a second target reagent to the reaction container so that the sample and the second target reagent are mixed to form a second target reaction solution; and control the detection device to detect the second target reaction solution to obtain second detection data.

[0248] In some embodiments, the analyzer execution body further includes an input device, and the method further includes:

[0249] Obtain the input information of the input device, and control the analyzer execution body to use the third detection process or the second detection process to detect the sample according to the input information.

[0250] In some embodiments, the analyzer execution body further includes a scanning device, and the sample is carried in a sample container. The method further includes:

[0251] Control the scanning device to scan the barcode information set on the sample container, and obtain the detection item information corresponding to the sample according to the scanning result of the barcode information;

[0252] When the detection item information is preset detection item information, use the third detection process to detect the sample;

[0253] When the detection item information is non-preset detection item information, use the second detection process to detect the sample.

[0254] In some embodiments, the analyzer execution body further includes an image processing device, and the method further includes:

[0255] Control the image processing device to collect the sample image of the sample and obtain the interference information in the sample;

[0256] Detect the sample by using the third detection process or the second detection process according to the interference information.

[0257] In some embodiments, the method further includes:

[0258] Obtain the detection item information corresponding to the sample, control the dispensing device to dispense the sample and the second target reagent into the reaction container, so that the sample and the second target reagent are mixed to form a second target reaction solution; and control the detection device to detect the second target reaction solution to obtain second detection data;

[0259] When it is determined according to the second detection data that the sample needs to be retested, control the analyzer execution body to perform the second pretreatment operation on the sample;

[0260] After the second pretreatment operation is completed, control the dispensing device to aspirate the second test solution from the third reaction container and dispense it into the fourth reaction container, and add the third target reagent to the fourth reaction container to prepare a third target reaction solution;

[0261] Control the detection device to detect the third target reaction solution, obtain third detection data, and output a detection result according to the third detection data;

[0262] When it is determined according to the item detection data that there is no need to perform a re - inspection on the sample, output a detection result according to the second detection data.

[0263] In some embodiments, the method further includes: during the process of the dispensing device sucking the third test solution from the third reaction container, controlling the magnetic adsorption device to perform magnetic adsorption on the solution in the third reaction container.

[0264] In some embodiments, the analyzer execution body further includes a first scheduling device and a second scheduling device. The magnetic adsorption of the third mixed solution by the magnetic adsorption device includes:

[0265] Control the first scheduling device to schedule the third reaction container carrying the third mixed solution to the carrying position on the second scheduling device, and control the second scheduling device to schedule the third reaction container to the suction position where the dispensing device performs sucking the third test solution;

[0266] Wherein, during the process of the second scheduling device scheduling the third reaction container to the suction position, control the magnetic adsorption device to perform magnetic adsorption on the third mixed solution in the third reaction container located at the carrying position.

[0267] In some embodiments, the analyzer execution body performs a detection operation on a sample within a sample detection cycle, and the sample detection cycle at least includes a dispensing action cycle and a detection action cycle;

[0268] The method includes: within the dispensing action cycle, controlling the dispensing device to perform sample dispensing and reagent dispensing into corresponding reaction containers, and within the detection action cycle, controlling the detection device to detect the reaction solution;

[0269] The method further includes: before controlling the analyzer execution body to perform a third pre - treatment operation on the sample, inserting a second sample pre - treatment cycle before the analyzer execution body executes the dispensing action cycle;

[0270] Within the second sample pre - treatment cycle, the controller controls the analyzer execution body to perform the first pre - treatment operation on the sample.

[0271] In some embodiments, the first cycle duration corresponding to the sample pre - treatment cycle is an integer multiple of the second cycle duration corresponding to the dispensing action cycle.

[0272] In some embodiments, during the execution entity's execution of the same detection item on the sample, the third detection process has a third calibration coefficient, and the second detection process has a second calibration coefficient different from the third calibration coefficient;

[0273] Wherein, after controlling the detection device to detect the third target reaction solution to obtain third detection data, the method further includes:

[0274] Obtaining a third detection result of the sample based on the third detection data and the third calibration coefficient, and outputting the third detection result;

[0275] After controlling the detection device to detect the second target reaction solution to obtain second detection data, the method further includes:

[0276] Obtaining a second detection result of the sample based on the second detection data and the second calibration coefficient, and outputting the second detection result.

[0277] It should be noted that those skilled in the art can clearly understand that for the convenience and brevity of description, the specific working process of the above-described sample analysis method can refer to the corresponding working process of the foregoing sample analyzer, which will not be elaborated herein.

[0278] It should be understood that the terms used in this specification of the present application are only for the purpose of describing specific embodiments and are not intended to limit the present application. As used in this specification of the present application and the appended claims, unless the context clearly indicates otherwise, the singular forms "a", "an" and "the" are intended to include the plural forms.

[0279] It should also be understood that the term "and / or" used in this specification of the present application and the appended claims refers to any combination and all possible combinations of one or more of the associated listed items, and includes these combinations. It should be noted that in this text, the term "comprises", "comprising" or any other variation thereof is intended to cover a non-exclusive inclusion, such that a process, method, article or system comprising a series of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article or system. Without further limitation, an element defined by the phrase "comprising a..." does not exclude the existence of additional identical elements in the process, method, article or system comprising the element.

[0280] The serial numbers of the embodiments of the present application above are only for description and do not represent the superiority or inferiority of the embodiments. As described above, the above is only a specific implementation manner of the present application, but the protection scope of the present application is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present application can easily think of various equivalent modifications or substitutions, and these modifications or substitutions should all be covered within the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims

1. A sample analyzer, characterized in that, Including: An analyzer execution body and a controller communicatively connected to the analyzer execution body, where the analyzer execution body at least includes a dispensing device, a reaction device, a magnetic adsorption device, and a detection device; The dispensing device is at least used for dispensing samples and / or reagents; The reaction device is provided with at least one reaction position for placing a reaction container, and the reaction container is used for receiving the samples and reagents dispensed by the dispensing device; The magnetic adsorption device is used for performing magnetic adsorption on the mixed solution, and the mixed solution is at least formed by mixing the sample and a pretreated magnetic bead reagent; The detection device is used for detecting the reaction solution to obtain corresponding detection data; The controller is at least used for: Controlling the analyzer execution body to perform a first pretreatment operation on the sample. Wherein, the first pretreatment operation includes: controlling the dispensing device to add the sample and a first magnetic bead reagent to a first reaction container so that the sample and the first magnetic bead reagent are mixed to form a first mixed solution, and the first magnetic bead reagent is used for adsorbing interfering substances in the sample; and controlling the magnetic adsorption device to perform magnetic adsorption on the first mixed solution so that the first mixed solution is separated into a first magnetic bead particulate matter and a first test solution, and the first test solution contains the analyte; After the first pretreatment operation is completed, controlling the dispensing device to aspirate the first test solution from the first reaction container and dispense it into a second reaction container, and adding a first target reagent to the second reaction container to prepare a first target reaction solution; Controlling the detection device to detect the first target reaction solution to obtain first detection data.

2. The sample analyzer according to claim 1, characterized in that, The sample analyzer is provided with a first detection process and a second detection process for detecting the sample. When the sample analyzer uses the first detection process to detect the sample, the controller executes: Controlling the analyzer execution body to perform the first pretreatment operation on the sample; After the first pretreatment operation is completed, controlling the dispensing device to aspirate the first test solution from the first reaction container and dispense it into a second reaction container, and adding a first target reagent to the second reaction container to prepare a first target reaction solution; Controlling the detection device to detect the first target reaction solution to obtain first detection data; When the sample analyzer uses the second detection process to detect the sample, the controller executes: Controlling the dispensing device to add the sample and a second target reagent to the reaction container so that the sample and the second target reagent are mixed to form a second target reaction solution; and controlling the detection device to detect the second target reaction solution to obtain second detection data.

3. The sample analyzer according to claim 2, characterized in that, The analyzer execution body further includes an input device, and the controller is further used for: Obtaining the input information of the input device and controlling the analyzer execution body to use the first detection process or the second detection process to detect the sample according to the input information.

4. The sample analyzer according to claim 2, wherein The analyzer execution body further includes a scanning device, the sample is carried on a sample container, and the controller is further used for: Control the scanning device to scan the barcode information set on the sample container, and obtain the detection item information corresponding to the sample according to the scanning result of the barcode information; When the detection item information is preset detection item information, use the first detection process to detect the sample; When the detection item information is non-preset detection item information, use the second detection process to detect the sample.

5. The sample analyzer according to claim 2, characterized in that, The analyzer execution body further includes an image processing device, and the controller is further used for: Control the image processing device to collect the sample image of the sample, and obtain the interference information in the sample; Detect the sample according to the interference information by using the first detection process or the second detection process.

6. The sample analyzer according to claim 1, wherein The controller is further used for: Obtain the detection item information corresponding to the sample, control the dispensing device to dispense the sample and the second target reagent into the reaction container, so that the sample and the second target reagent are mixed to form a second target reaction solution; And control the detection device to detect the second target reaction solution to obtain second detection data; When it is determined according to the second detection data that the sample needs to be retested, control the analyzer execution body to perform the first pretreatment operation on the sample; After the first pretreatment operation is completed, control the dispensing device to suck the first test solution from the first reaction container and dispense it into the second reaction container, and add the first target reagent to the second reaction container to prepare a first target reaction solution; Control the detection device to detect the first target reaction solution, obtain the first detection data and output the detection result according to the first detection data; When it is determined according to the project detection data that the sample does not need to be retested, output the detection result according to the second detection data.

7. The sample analyzer according to any one of claims 1-6, characterized in that, The controller is further used for: during the process of the dispensing device sucking the first test solution from the first reaction container, control the magnetic adsorption device to perform magnetic adsorption on the solution in the first reaction container.

8. The sample analyzer according to any one of claims 1-7, characterized in that, The analyzer execution body further includes a first scheduling device and a second scheduling device. During the process of the controller controlling the magnetic adsorption device to perform magnetic adsorption on the first mixed solution, it includes: Control the first scheduling device to schedule the first reaction container carrying the first mixed solution to the carrying position located on the second scheduling device, and control the second scheduling device to schedule the first reaction container to the suction position where the dispensing device sucks the first test solution; Wherein, during the process of the second scheduling device scheduling the first reaction container to the suction position, control the magnetic adsorption device to perform magnetic adsorption on the first mixed solution in the first reaction container located at the carrying position.

9. The sample analyzer according to any one of claims 1-8, characterized in that, The analyzer execution body performs a detection operation on the sample within the sample detection cycle, and the sample detection cycle at least includes a dispensing action cycle and a detection action cycle; The controller is used for: within the dispensing action cycle, control the dispensing device to perform sample dispensing and reagent dispensing to the corresponding reaction container, and within the detection action cycle, control the detection device to detect the reaction solution; The controller is further configured to insert a sample pre - treatment cycle before the analyzer execution body executes the dispensing action cycle and before controlling the analyzer execution body to perform a first pre - treatment operation on the sample; During the sample pre - treatment cycle, the controller controls the analyzer execution body to perform the first pre - treatment operation on the sample.

10. The sample analyzer according to claim 9, wherein, The first cycle duration corresponding to the sample pre - treatment cycle is an integer multiple of the second cycle duration corresponding to the dispensing action cycle.

11. The sample analyzer according to any one of claims 2-10, characterized in that, During the process of the execution body performing the same detection item on the sample, the first detection process has a first calibration coefficient, and the second detection process has a second calibration coefficient different from the first calibration coefficient; Wherein, after the controller controls the detection device to detect the first target reaction liquid and obtains first detection data, it performs: Obtaining a first detection result of the sample according to the first detection data and the first calibration coefficient, and outputting the first detection result; After the controller controls the detection device to detect the second target reaction liquid and obtains second detection data, it performs: Obtaining a second detection result of the sample according to the second detection data and the second calibration coefficient, and outputting the second detection result.

12. A sample analyzer, characterized in that, Including: An analyzer execution body and a controller communicatively connected to the analyzer execution body, where the analyzer execution body at least includes a dispensing device, a reaction device, a magnetic adsorption device, and a detection device; The dispensing device is at least used for dispensing samples and / or reagents; The reaction device is provided with at least one reaction position for placing reaction containers, and the reaction containers are used to receive the samples and reagents dispensed by the dispensing device; The magnetic adsorption device is used for performing magnetic adsorption on the mixed liquid, and the mixed liquid is at least formed by mixing the sample and a pretreatment magnetic bead reagent; The detection device is used for detecting the reaction liquid to obtain corresponding detection data; The controller is at least used for: Controlling the analyzer execution body to perform a second pre - treatment operation on the sample. Wherein, the second pre - treatment operation includes: controlling the analyzer execution body to dispense the sample and a second magnetic bead reagent into a third reaction container so that the sample and the second magnetic bead reagent are mixed to form a second mixed liquid, and the second magnetic bead reagent is used to adsorb the analyte in the sample; controlling the analyzer execution body to perform magnetic adsorption on the second mixed liquid so that the second mixed liquid is separated into a second magnetic bead particulate matter and a second liquid, and controlling the analyzer execution body to aspirate the second liquid in the third reaction container; controlling the analyzer execution body to dispense a displacement reagent into the third reaction container carrying the second magnetic bead particulate matter so that the displacement reagent and the second magnetic bead particulate matter are mixed to form a third mixed liquid, and the displacement reagent is used to displace the analyte from the second magnetic bead particulate matter; controlling the analyzer execution body to perform magnetic adsorption on the third mixed liquid so that the third mixed liquid is separated into a third magnetic bead particulate matter and a second analyte - containing liquid; After the execution of the second pretreatment operation is completed, control the analyzer execution body to aspirate the second test solution and dispense it into the fourth reaction container, and dispense a third target reagent into the fourth reaction container to prepare a third target reaction solution; Control the analyzer execution body to detect the third target reaction solution to obtain third detection data.

13. The sample analyzer according to claim 12, characterized in that, The analyzer execution body further includes a substrate dispensing device and a magnetic separation device. The third target reagent includes a third magnetic bead reagent and an enzyme-labeled reagent. During the process of the controller controlling the analyzer execution body to dispense the third target reagent into the fourth reaction container to prepare the third target reaction solution, the following operations are performed: Control the dispensing device to dispense the third magnetic bead reagent and the enzyme-labeled reagent into the fourth reaction container carrying the second test solution, so that the sample, the third magnetic bead reagent, and the enzyme-labeled reagent are mixed to form an initial reaction solution; Control the magnetic separation device to perform magnetic separation cleaning on the initial reaction solution to clean the impurities in the initial reaction solution; After the magnetic separation cleaning is completed, control the substrate dispensing device to add a substrate to the fourth reaction container to prepare and form the third target reaction solution.

14. The sample analyzer according to claim 12, characterized in that, The analyzer execution body is provided with a third detection process and a second detection process for detecting a sample. When the analyzer execution body uses the third detection process to detect the sample, the controller performs the following operations: Control the analyzer execution body to perform the second pretreatment operation on the sample; After the execution of the second pretreatment operation is completed, control the analyzer execution body to aspirate the second test solution and dispense it into the fourth reaction container, and add a third target reagent to the fourth reaction container to prepare a third target reaction solution; control the detection device to detect the third target reaction solution to obtain third detection data; When using the second detection process to detect the sample, the controller performs the following operations: Control the dispensing device to add the sample and a second target reagent to the reaction container, so that the sample and the second target reagent are mixed to form a second target reaction solution; and control the detection device to detect the second target reaction solution to obtain second detection data.

15. A sample analysis method, applied to a sample analyzer, the sample analyzer including an analyzer execution main body, characterized in that, The method includes: Control the analyzer execution body to perform a first pretreatment operation on the sample. The first pretreatment operation includes: controlling the dispensing device of the analyzer execution body to add the sample and a first magnetic bead reagent to the first reaction container, so that the sample and the first magnetic bead reagent are mixed to form a first mixed solution. The first magnetic bead reagent is used to adsorb the interfering substances in the sample; and controlling the magnetic adsorption device of the analyzer execution body to perform magnetic adsorption on the first mixed solution, so that the first mixed solution is separated to form a first magnetic bead particulate matter and a first test solution, and the first test solution contains the analyte; After the execution of the first pretreatment operation is completed, control the dispensing device to aspirate the first test solution from the first reaction container and dispense it into the second reaction container, and add a first target reagent to the second reaction container carrying the second reaction container to prepare a first target reaction solution; Control the detection device of the analyzer execution body to detect the first target reaction solution and output a first detection result.

16. A sample analysis method, applied to a sample analyzer, the sample analyzer including an analyzer execution main body, characterized in that, The method includes: Controlling the analyzer execution body of the sample analyzer to perform a second pretreatment operation on the sample, wherein the second pretreatment operation includes: controlling the analyzer execution body to dispense the sample and a second magnetic bead reagent into a third reaction container so that the sample and the second magnetic bead reagent are mixed to form a second mixed solution, and the second magnetic bead reagent is used to adsorb the analyte in the sample; controlling the analyzer execution body to perform magnetic adsorption on the second mixed solution so that the second mixed solution is separated to form second magnetic bead particles and a second liquid, and controlling the analyzer execution body to aspirate the second liquid in the third reaction container; controlling the analyzer execution body to dispense a displacement reagent into the third reaction container carrying the second magnetic bead particles so that the displacement reagent and the second magnetic bead particles are mixed to form a third mixed solution, and the displacement reagent is used to displace the analyte from the second magnetic bead particles; controlling the analyzer execution body to perform magnetic adsorption on the third mixed solution so that the third mixed solution is separated to form third magnetic bead particles and a second analyte solution, and the second analyte solution contains the analyte; After the second pretreatment operation is completed, controlling the analyzer execution body to aspirate the second analyte solution from the third reaction container and dispense it into a fourth reaction container, and dispense a third target reagent into the fourth reaction container to prepare a third target reaction solution; Controlling the analyzer execution body to detect the third target reaction solution to obtain third detection data.

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