Micellar two-phase cosmetic spray in non-aerosol mist package

Abstract

A cleansing composition comprising: an oily blend comprising one or more branched or linear liquid alkanes having a carbon chain length of C11 to C20, the branched or linear liquid alkanes comprising isohexadecane and isododecane, and one or more emollient esters; at least one polymeric thickener for use in water-based systems; at least one polyglycerol nonionic surfactant; and water, in a two-phase micelle system having an oil phase and an aqueous phase, the aqueous phase comprising water present in the range of from about 30% to about 70% by weight of the cleansing composition, where water and oil are present in a water to oil ratio of from about 1.5: 1 to about 1: 1.5. The product is removed by wiping without flushing with water.

Description

[0001] Related Applications

[0002] This application claims priority to U.S. Provisional Application No. 63 / 387,848, filed on December 16, 2022, entitled "MICELLAR BI-PHASE MAKEUP SPRAY IN A NON-AEROSOL FINE MIST PACKAGING", and French Application No. FR2303507, filed on April 7, 2023. The entire contents of these applications are incorporated herein by reference. Technical Field

[0003] The present invention relates to a makeup removing composition, and more particularly to a non-aerosol spray micellar bi-phase makeup removing composition. Background Art

[0004] Removing heavy makeup has always been a challenge and a pain point for consumers, especially for waterproof mascaras, long-lasting foundations, and longer-lasting lip products. Typical makeup removing products are unable to effectively remove heavy makeup, thus requiring repeated tugging and rubbing on the skin and / or delicate eye area, which can cause irritation. Some oil-based makeup removing products can easily remove makeup, but they can cause discomfort and greasiness to the skin. In addition, many commercially available makeup removing products require the use of wipes or pads for application, and can be cumbersome and result in product waste due to the saturation or dripping of the pads.

[0005] Spray-type products are easier to apply and can be applied more evenly, and then manually rubbed without wipes / pads, thus avoiding tugging on sensitive tissues. The main drawback of existing spray formulations is that they contain large amounts of oils, which can create a greasy feeling and leave the skin feeling far from the fresh and clean effect that most consumers desire. Other undesirable components in current makeup removing products include alcohols (which can cause dry skin), as well as sulfate-based surfactants, silicones, VOC propellants, and other synthetic components, which are less appealing to consumers seeking products containing natural components.

[0006] Therefore, there is a need for a composition in spray form that will provide easy and efficient makeup removal, leaving the skin feeling clean and fresh after use, and without the use of silicones, alcohols, and sulfates. Summary of the Invention

[0007] The present disclosure describes exemplary embodiments in accordance with the general inventive concept and is not intended to limit the scope of the present invention in any way. Indeed, the present invention as described in this specification is broader than and not limited to the exemplary embodiments set forth herein, and the terms used herein have their full ordinary meaning.

[0008] In various embodiments, the present disclosure provides a non-aerosol spray micellar two-phase makeup removing composition.

[0009] According to various embodiments, the makeup removing composition according to the present disclosure comprises: an oil blend comprising one or more branched or straight-chain liquid alkanes having a carbon chain length of C11 to C20, the branched or straight-chain liquid alkanes comprising isocetane and isododecane, and one or more emollient esters; at least one polymeric thickener for aqueous systems; at least one polyglycerol nonionic surfactant; and water, in a two-phase micellar system comprising an oil phase and an aqueous phase, the aqueous phase comprising water present in an amount of about 30 wt% to about 70 wt% of the makeup removing composition, wherein the water and the oil are present in a water-to-oil ratio of about 1.5:1 to about 1:1.5.

[0010] In one embodiment, the present disclosure provides a makeup removing composition comprising: a two-phase micellar system comprising an oil phase and an aqueous phase, the system comprising:

[0011] a. an oil blend comprising

[0012] i. one or more branched or straight-chain liquid alkanes having a carbon chain length of C11 to C20, which comprise isocetane and isododecane, and

[0013] ii. one or more emollient esters;

[0014] b. at least one polymeric thickener for aqueous systems;

[0015] c. at least one polyglycerol nonionic surfactant; and

[0016] d. water present in an amount of about 30 wt% to about 70 wt% of the makeup removing composition;

[0017] wherein the composition is a micellar two-phase system, wherein the water and the oil are present in a water-to-oil ratio of about 1.5:1 to about 1:1.5.

[0018] According to various embodiments, the makeup removing composition is formulated as an aesthetic two-phase preparation having a phase interface that allows for easy makeup removal without greasiness and contains few or no components that may be irritating to the skin or eyes.

[0019] In some embodiments, the makeup removing composition is substantially free of silicone.

[0020] In some embodiments, the composition does not contain silicone and one or more of the following: alcohols, sulfate-containing compounds, PEG surfactants, xanthan gum, or combinations thereof.

[0021] In various embodiments, the makeup removing composition may further comprise one or more additives, including preservatives, fragrances, active substances, pH regulators, and other cosmetically acceptable additives.

[0022] In some embodiments, one or more emollient esters comprise isopropyl myristate, and at least one polymeric thickener for aqueous systems comprises hydroxyethyl cellulose.

[0023] In some embodiments, based on the weight of the makeup removing composition, isoeicosane is present in an amount of about 15 wt% to about 30 wt%, and isododecane is present in an amount of about 10 wt% to about 20 wt%.

[0024] In some embodiments, based on the weight of the makeup removing composition, isoeicosane is present in an amount of about 28 wt%, and isododecane is present in an amount of about 15 wt%.

[0025] In some embodiments, based on the weight of the makeup removing composition, one or more emollient esters are present in an amount of about 1 wt% to about 8 wt%.

[0026] In some embodiments, based on the weight of the makeup removing composition, one or more emollient esters comprise isopropyl myristate present in an amount of about 1 wt% to about 8 wt%.

[0027] In some embodiments, the total amount of emollient esters does not exceed a total of about 10 wt% of the makeup removing composition.

[0028] In some embodiments, based on the weight of the makeup removing composition, at least one polymeric thickener for aqueous systems is present in an amount of about 0.01 wt% to about 1.0 wt%.

[0029] In some embodiments, at least one polymeric thickener for aqueous systems comprises hydroxyethyl cellulose.

[0030] In some embodiments, based on the weight of the composition, at least one polyglycerol nonionic surfactant is present in a total amount of about 0.01 wt% to about 0.2 wt%.

[0031] In some embodiments, at least one polyglycerol nonionic surfactant comprises polyglyceryl-6 caprylate and polyglyceryl didecanoate.

[0032] In some embodiments, based on the weight of the composition, at least one polyglycerol nonionic surfactant comprises polyglyceryl-6 caprylate present in an amount of about 0.025 wt% and polyglyceryl didecanoate present in an amount of about 0.025 wt%.

[0033] In some embodiments, the makeup removing composition comprises triethyl citrate.

[0034] In some embodiments, the makeup removing composition comprises one or a combination of additives selected from the following: sodium hydroxide, panthenol, hydroxyacetophenone, gluconolactone, myristyl trimethyl ammonium bromide, sodium citrate, sodium chloride, dioctyl ether, citric acid, or a combination thereof.

[0035] In some embodiments, the present disclosure provides a makeup removing composition comprising: a biphasic micellar system comprising an oil phase and an aqueous phase, the system comprising:

[0036] a. An oil blend comprising

[0037] i. One or more branched or straight-chain liquid alkanes having a carbon chain length of C11 to C20, comprising isododecane present at about 28% by weight and isocetane present at about 15% by weight, and

[0038] ii. One or more emollient esters, comprising isopropyl myristate present at about 1% by weight;

[0039] b. At least one polymeric thickener for an aqueous system, comprising hydroxyethyl cellulose present at about 0.025% by weight;

[0040] c. At least one polyglycerol nonionic surfactant, comprising polyglyceryl-6 caprylate present at about 0.025% by weight and polyglyceryl didodecanoate present at about 0.025% by weight;

[0041] d. Water present at about 45% to about 55% by weight;

[0042] e. Triethyl citrate; and

[0043] f. One or a combination of additives selected from the following: sodium hydroxide, panthenol, hydroxyacetophenone, gluconolactone, myristyl trimethyl ammonium bromide, sodium citrate, sodium chloride, dioctyl ether, citric acid, or a combination thereof,

[0044] All amounts are by weight based on the weight of the makeup removing composition,

[0045] wherein the composition is a micellar biphasic system, wherein water and oil are present in a water-to-oil ratio of about 1:1.

[0046] In some embodiments, the present disclosure provides a product comprising: a container containing a makeup removing composition according to the present invention; an outlet in communication with the container, such as an outlet of a spray nozzle; and a spraying device, wherein the spraying device is capable of releasing the makeup removing composition in the container via the outlet, wherein the spray nozzle is a fine mist nozzle, the fine mist nozzle has a pump volume for delivering mist of about 0.02 ml (about 0.01 to about 1.0 ml / pump), and has particles (droplets) in the micron size range of about 10 microns to about 900 microns or about 40 microns to about 300 microns or an average size of about 80 to about 100 microns. In some such embodiments, the makeup removing composition contained in the container is transparent or translucent, wherein the term "translucent" refers to the property of a material that allows light to pass through a 5 mm thick sample without being able to distinguish alphanumeric characters, and the term "transparent" refers to the property of a material that allows light to pass through a 5 mm thick sample and is able to distinguish alphanumeric characters. In some specific embodiments, the atomized droplets are also transparent or translucent.

[0047] The makeup removing composition can be applied and removed by wiping without rinsing with water.

[0048] These and other aspects of the invention are set forth in the appended claims and are described in more detail in the detailed description of the invention.

[0049] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and do not limit the present disclosure. BRIEF DESCRIPTION OF THE DRAWINGS

[0050] The features and advantages of the general concept of the present invention become apparent by reference to the following detailed description taken in conjunction with the drawings.

[0051] Figure 1 is a chart showing the test characteristics of the makeup removing composition of the present invention;

[0052] Figure 2 is a chart showing the test characteristics of the makeup removing composition of the present invention;

[0053] Figure 3 is a chart showing the clinical test experience of subjects using the makeup removing composition of the present invention and a comparative composition.

[0054] Figure 4 is a chart showing the clinical test experience of subjects using the makeup removing composition of the present invention and a comparative composition with a nebulizing pump and an aerosol spray device, respectively. DETAILED DESCRIPTION

[0055] "Keratin matrix" and "keratin tissue" each include, but are not limited to, skin, hair, and nails.

[0056] "Cosmetically acceptable" means a vehicle that is compatible with any horny substrate.

[0057] "Silicone-free" means that, based on the total weight of the makeup remover composition, it contains less than 5% by weight, or less than 4% by weight, or less than 3% by weight, or less than 2% by weight, or less than 1% by weight, or less than 0.1% by weight of silicone, such as silicone polymers, for example selected from dimethicone and other silicone oils, and silicone elastomers.

[0058] "Stability" is demonstrated by one or both of naked-eye or microscopic examination. For the purposes of this article, a composition shows physical stability, does not show phase instability, and maintains two stable phases that are mixed essentially only by agitation. In various embodiments, the compositions of the present invention remain stable at a temperature of about 4°C to about 45°C for at least one month, or at least two months or longer, or any value, range, or sub-range therebetween. In some embodiments, the makeup remover composition is stable at 25°C for at least one month, or at least two months, or at least three months or longer, or any value, range, or sub-range therebetween. In some embodiments, the makeup remover composition is stable at 37°C for at least one month, or at least two months, or at least three months or longer, or any value, range, or sub-range therebetween. As disclosed and exemplified herein, the makeup remover composition is stable at 4°C for at least one month, or at least two months, or at least three months or longer, or any value, range, or sub-range therebetween. And as disclosed and exemplified herein, the makeup remover composition remains stable through at least 10 freeze-thaw cycles.

[0059] According to the present disclosure, the compositions of the present invention overcome the disadvantages of the prior art and provide unexpected benefits, including easy overall makeup removal, easy removal of liquid foundation, leaving the skin feeling clean, fresh, soft, and smooth, easy removal of mascara (ordinary and waterproof types) by gentle wiping, and leaving no greasy feeling or residue.

[0060] In some embodiments, the makeup remover composition is a silicone-free, alcohol-free two-phase makeup remover in a spray-form product that is non-aerosol and produces a fine mist, wherein the aqueous phase is proven to be a micellar technology and the ingredients are mainly natural or nature-based. In some embodiments, the makeup remover composition is a two-phase system having 50% oil and 50% water (by mass).

[0061] In various embodiments, the makeup removing composition is shaken or stirred immediately before application to form an emulsion. In some embodiments, the makeup removing composition of the present invention exhibits phase separation after shaking. In some embodiments, upon stirring, the makeup removing composition forms a milky white single phase, which separates back into three or more distinct phases over a period of up to 24 hours. In some embodiments, the makeup removing composition of the present invention exhibits phase separation after shaking, wherein after stopping stirring, a slow initial phase separation is shown to achieve a sufficiently uniform emulsion before dispensing. In some embodiments, the makeup removing composition of the present invention shows clear container walls with very few visible droplets to the naked eye after stopping stirring, with substantially no adhering or trailing layer on the container walls and no or very few visible droplets at any phase interface. In some embodiments, the makeup removing composition shows excellent ability to remove long-lasting mascara and long-lasting foundation.

[0062] Spray delivery of the makeup removing composition allows for more contact time of the composition on the skin, most effectively removing makeup. The optimized oil-to-water ratio within the ranges disclosed and exemplified herein provides an ideal makeup removing effect for all types of cosmetics. The optimized water content as disclosed and exemplified herein eliminates residues on the skin, especially compared to anhydrous, highly oily and silicone-containing compositions. The optimized combination and composition of hydrocarbons of different chain lengths in the oil phase provide an ideal makeup removing effect, especially for waterproof cosmetics, most especially waterproof mascara.

[0063] Compared to a reference product containing a propellant, silicone, alcohols and other less desirable ingredients, the makeup removing composition according to the present disclosure differs from the reference in that it is dispensed as a fine mist without using an aerosolizing propellant upon leaving the aerosol package, providing a pleasant mist and enhanced stability. Due to the lack of silicone, the makeup removing composition addresses the greasiness and oiliness after use, which are the main areas of negative reviews for competing products. In addition, the makeup removing composition does not contain irritating chemicals (silicone, alcohols, parabens, fragrances, sulfates). Compared to traditional micelles without a spray, the spray form of the makeup removing composition is most effective in removing makeup. This biphasic nature removes all types of cosmetics at once, including long-lasting mascara. In addition, as exemplified herein, compared to 100% anhydrous competing formulations, the aqueous phase of the makeup removing composition is micellar, showing loosening of heavy makeup and no greasy residue, and further enhancing the cleaning ability. The makeup removing composition is gentle on the skin, non-irritating to the skin and eyes, and provides a clean skin surface to reduce the need for rinsing after application, thereby reducing water consumption.

[0064] Through expert evaluation of the makeup removal effect, the makeup removal composition according to the present disclosure shows comparable performance to competing silicone-containing anhydrous compositions in removing liquid foundation and is excellent in removing eye and lip cosmetics. Consumer tests also show that the makeup removal composition is more popular than the competing benchmark and does not leave any greasy residue. And the makeup removal composition is also rated highly efficient in removing mascara and is gentle on the skin. In vitro tests prove that the composition does not adversely affect the skin condition, and the osmotic pressure data together with the clinical tests indicate that the makeup removal composition is non-irritating to the eyes.

[0065] According to various embodiments, the makeup removal composition according to the present disclosure comprises: an oil blend comprising one or more branched or straight-chain liquid alkanes having a carbon chain length of C11 to C20, the branched or straight-chain liquid alkanes comprising isocetane and isododecane, and one or more emollient esters; at least one polymeric thickener for water-based systems; at least one polyglycerol nonionic surfactant; and water, in a biphasic micellar system comprising an oil phase and an aqueous phase, the aqueous phase comprising water present in an amount of about 30 wt% to about 70 wt% of the makeup removal composition, wherein the water and the oil are present in a water-to-oil ratio of about 1.5:1 to about 1:1.5. The removal of the composition can be accomplished by wiping without the need for rinsing or washing as is typically required for compositions loaded with oils and surfactants such as the benchmark.

[0066] (i) Branched or straight-chain liquid paraffin

[0067] According to the present disclosure, the makeup removal composition comprises at least one branched or straight-chain liquid alkane having a carbon chain length of C11 to C20. In various embodiments, the liquid alkane can be selected from those liquid alkanes having a carbon chain length of C11 to C20. The liquid alkane can be selected from those liquid alkanes having a carbon chain length of C11 to C20, or C15 to C19, or one of C11, C12, C13, C14, C15, C16, C17, C18 to C19. In some specific embodiments, suitable liquid alkanes that can be used according to the present disclosure include hydrocarbon-based oils containing 8 to 16 carbon atoms, especially branched C8-C16 alkanes, such as C8-C16 isoparaffins. In some exemplary embodiments, such liquid alkanes can be selected from isoparaffins, such as isododecane (also known as 2,2,4,4,6-pentamethylheptane), isodecane, and isocetane.

[0068] In some embodiments, at least one branched or straight-chain liquid alkane comprises isocetane, C15-19 alkanes, isododecane, undecane, tridecane, and combinations thereof. In some embodiments, the makeup removal composition comprises two or more branched or straight-chain liquid alkanes.

[0069] In some embodiments, the branched or straight-chain liquid alkane comprises isocetane and isododecane.

[0070] In some embodiments, based on the weight of the makeup removing composition, isoeicosane is present in an amount of from about 15% to about 30% by weight, and isododecane is present in an amount of from about 10% to about 20% by weight.

[0071] In some embodiments, based on the weight of the makeup removing composition, isoeicosane is present in an amount of about 28% by weight, and isododecane is present in an amount of about 15% by weight.

[0072] Based on the weight of the makeup removing composition, the amount of each of at least one branched or straight-chain liquid alkane present in the makeup removing composition is from about 1% to about 35% by weight, or from about 15% to about 30% by weight, or from about 10% to about 20% by weight, or any suitable combination, sub-combination, range or sub-range thereof. However, those of ordinary skill in the art will understand that other ranges are within the scope of the present invention.

[0073] Thus, based on the total weight of the makeup removing composition, each of at least one branched or straight-chain liquid alkane in the makeup removing composition can be present in an amount of about 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34% to about 35% by weight (including increments and ranges therein and therebetween).

[0074] (ii) Emollient ester

[0075] According to the present disclosure, the makeup removing composition comprises at least one emollient ester, which in some embodiments is a branched alkylated alcohol ester.

[0076] In some embodiments, suitable emollient esters that can be used according to the present disclosure may be selected from isopropyl myristate, isopropyl palmitate, ethylhexyl palmitate, methyl palmitate, 2-ethylhexyl palmitate, hexyl laurate, ethylhexyl laurate, isopropyl laurate, ethylhexyl oleate, ethylhexyl isononanoate, isononyl isononanoate, myristyl myristate, 2-ethylhexyl octanoate / caprate (or octyl octanoate / caprate), isostearyl neopentanoate, cetearyl ethylhexanoate, isopropyl isostearate, diisopropyl sebacate, coco-caprylate / caprate, diisopropyl adipate, and combinations of esters of lactic acid and fatty alcohols containing 12 or 13 carbon atoms, and combinations thereof.

[0077] In some specific embodiments, at least one emollient ester comprises isopropyl myristate.

[0078] In some embodiments, based on the weight of the makeup removing composition, one or more emollient esters are present in an amount of about 1 wt% to about 8 wt%.

[0079] In some embodiments, based on the weight of the makeup removing composition, one or more emollient esters comprise isopropyl myristate present in an amount of about 1 wt% to about 8 wt%.

[0080] In some embodiments, the total amount of emollient esters does not exceed about 10 wt% of the total makeup removing composition.

[0081] In some embodiments, the makeup removing composition comprises two or more emollient esters. In some such embodiments, at least one emollient ester comprises isopropyl myristate and one or more additional emollient esters. In some specific embodiments, the makeup removing composition comprises isopropyl myristate, isopropyl palmitate, and ethylhexyl palmitate.

[0082] According to various embodiments, based on the weight of the makeup removing composition, each of at least one emollient ester is present in the makeup removing composition in an amount of about 0.1 wt% to about 15 wt%, or about 1 wt% to about 10 wt%, or about 1 wt% to about 8 wt%, or about 1 wt%, or any suitable combination, sub - combination, range, or sub - range thereof. Based on the weight of the makeup removing composition, the total amount of emollient esters present in the makeup removing composition is about 0.1 wt% to about 15 wt%, or about 1 wt% to about 8 wt%, or any suitable combination, sub - combination, range, or sub - range thereof. However, one of ordinary skill in the art will understand that other ranges are within the scope of the present invention.

[0083] Thus, based on the total weight of the makeup removing composition, each of at least one emollient ester in the makeup removing composition can be present in an amount of about 0.1 wt%, 0.2 wt%, 0.3 wt%, 0.4 wt%, 0.5 wt%, 0.6 wt%, 0.7 wt%, 0.8 wt%, 0.9 wt%, 1 wt%, 2 wt%, 3 wt%, 4 wt%, 5 wt%, 6 wt%, 7 wt%, 8 wt%, 9 wt%, 10 wt%, 11 wt%, 12 wt%, 13 wt%, 14 wt% to about 15 wt% (including increments and ranges therein and therebetween).

[0084] (iii) Polymer

[0085] In various embodiments, the makeup removing composition comprises at least one polymer. In some embodiments, at least one polymer is selected from the group consisting of cellulose, gums, hydrocolloids, and combinations thereof.

[0086] The polymer can be selected from the group consisting of: nonionic, anionic, cationic, and amphoteric polymers, such as polysaccharides, including chitosan, chitin, starch, alginate, cellulose; galactomannans, such as guar gum and its derivatives, including hydroxypropyl guar gum, cationic guar gum derivatives, gums from microbial sources (including xanthan gum, scleroglucan gum, mucopolysaccharides, chondroitin sulfate, and mixtures thereof), and gums derived from plant exudates (including locust bean gum, gum arabic, ghatti gum, karaya gum, tragacanth gum, carrageenan, agar gum, and carob gum); cellulose-based polymers, including methylcellulose, hydroxyalkylcellulose, ethylhydroxyethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, cationic cellulose ether derivatives, quaternized cellulose derivatives, nitrocellulose, hemicellulose, and hemicellulose derivatives; mannans, xylans, lignin, arabinans, galacturonans, alginate-based compounds, glucuronoxylan, arabinoxylan, xyloglucan, glucomannan, fructans (such as inulin, pectic acid, and pectin), arabinogalactan, agar, mucopolysaccharides, gelatin, gellan gum, crosslinked homopolymers of acrylic acid; and combinations thereof.

[0087] In some specific embodiments, the makeup removing composition comprises at least one polymer, and the at least one polymer comprises hydroxyethylcellulose. In some embodiments, the makeup removing composition does not comprise a thickening agent, and the thickening agent includes xanthan gum.

[0088] In some embodiments, based on the weight of the makeup removing composition, at least one polymeric thickening agent for aqueous systems is present in an amount of from about 0.01 wt% to about 1.0 wt%.

[0089] In some embodiments, at least one polymeric thickening agent for aqueous systems comprises hydroxyethylcellulose.

[0090] Based on the weight of the makeup removing composition, the at least one polymer present in the makeup removing composition according to the present disclosure is from about 0.01 wt% to about 10 wt%, or from about 0.01 wt% to about 5 wt%, or from about 0.01 wt% to about 1 wt%, or from about 0.0 wt% to about 0.03 wt%, or about 0.025 wt%, or any suitable combination, sub-combination, range, or sub-range thereof.

[0091] Thus, based on the total weight of the makeup removing composition, one or a combination of the polymers may be present in an amount of from about 0.01 wt%, 0.015 wt%, 0.02 wt%, 0.025 wt%, 0.03 wt%, 0.035 wt%, 0.04 wt%, 0.045 wt%, 0.05 wt%, 0.055 wt%, 0.06 wt%, 0.065 wt%, 0.07 wt%, 0.075 wt%, 0.08 wt%, 0.085 wt%, 0.09 wt%, 0.095 wt%, 0.1 wt%, 0.2 wt%, 0.3 wt%, 0.4 wt%, 0.5 wt%, 0.6 wt%, 0.7 wt%, 0.8 wt%, 0.9 wt%, 1.0 wt%, 2 wt%, 3 wt%, 4 wt%, 5 wt%, 6 wt%, 7 wt%, 8 wt%, 9 wt% to about 10 wt% (including increments and ranges therein and therebetween).

[0092] (iv) Polyglycerol nonionic surfactant

[0093] According to various embodiments, the makeup removing composition comprises at least one polyglycerol nonionic surfactant. In some embodiments, the at least one nonionic surfactant may be selected from polyglycerol nonionic surfactants selected from the group consisting of: polyglycerol esters, polyglycerol ethers, polyglycerol sorbitan fatty acid esters, combinations of two or more thereof, and the like. In some embodiments, the at least one nonionic surfactant is selected from polyglycerol esters, polyglycerol ethers, and combinations of two or more thereof.

[0094] In some embodiments, at least one nonionic surfactant is selected from polyglycerol nonionic surfactants, and the polyglycerol nonionic surfactants are selected from the group consisting of: polyglycerol-4 caprylate / caprate, polyglycerol-5 caprylate / caprate, polyglycerol-6 caprylate / caprate, polyglycerol-7 caprylate / caprate, polyglycerol-8 caprylate / caprate, polyglycerol-9 caprylate / caprate, polyglycerol-10 caprylate / caprate, polyglycerol-4 caprate, polyglycerol-5 caprate, polyglycerol-6 caprate, polyglycerol-7 caprate, polyglycerol-8 caprate, polyglycerol-9 caprate, polyglycerol-10 caprate, polyglycerol-4 laurate, polyglycerol-5 laurate, polyglycerol-6 laurate, polyglycerol-7 laurate, polyglycerol-8 laurate, polyglycerol-9 laurate, polyglycerol-10 laurate, polyglycerol-6 cocoate, polyglycerol-7 cocoate, polyglycerol-8 cocoate, polyglycerol-9 cocoate, polyglycerol-10 cocoate, polyglycerol-11 cocoate, polyglycerol-12 cocoate, polyglycerol-6 myristate, polyglycerol-7 myristate, polyglycerol-8 myristate, polyglycerol-9 myristate, polyglycerol-10 myristate, polyglycerol-11 myristate, polyglycerol-12 myristate, polyglycerol-10 oleate, polyglycerol-11 oleate, polyglycerol-12 oleate, polyglycerol-10 stearate, polyglycerol-11 stearate, polyglycerol-12 stearate, and combinations of two or more thereof.

[0095] In some embodiments, at least one nonionic surfactant is selected from: polyglyceryl-2 oleate, polyglyceryl-4 caprylate / caprate, polyglyceryl-5 caprylate / caprate, polyglyceryl-6 didecanoate, polyglyceryl-6 caprylate / caprate, polyglyceryl-7 caprylate / caprate, polyglyceryl-8 caprylate / caprate, polyglyceryl-9 caprylate / caprate, polyglyceryl-10 caprylate / caprate, polyglyceryl-4 decanoate, polyglyceryl-5 decanoate, polyglyceryl-6 decanoate, polyglyceryl-7 decanoate, polyglyceryl-8 decanoate, polyglyceryl-9 decanoate, polyglyceryl-10 decanoate, polyglyceryl-4 laurate, polyglyceryl-5 laurate, polyglyceryl-6 laurate, polyglyceryl-7 laurate, polyglyceryl-8 laurate, polyglyceryl-9 laurate, polyglyceryl-10 laurate, polyglyceryl-6 cocoate, polyglyceryl-7 cocoate, polyglyceryl-8 cocoate, polyglyceryl-9 cocoate, polyglyceryl-10 cocoate, polyglyceryl-11 cocoate, polyglyceryl-12 cocoate, polyglyceryl-6 myristate, polyglyceryl-7 myristate, polyglyceryl-8 myristate, polyglyceryl-9 myristate, polyglyceryl-10 myristate, polyglyceryl-11 myristate, polyglyceryl-12 myristate, polyglyceryl-10 oleate, polyglyceryl-11 oleate, polyglyceryl-12 oleate, polyglyceryl-10 stearate, polyglyceryl-11 stearate, polyglyceryl-12 stearate, and combinations of two or more thereof.

[0096] In some embodiments, the makeup removing composition comprises one nonionic surfactant. In some embodiments, the makeup removing composition comprises at least two or more nonionic surfactants.

[0097] In some embodiments, the makeup removing composition comprises polyglyceryl-6 caprylate and polyglyceryl didecanoate.

[0098] In some embodiments, based on the weight of the composition, at least one polyglyceryl nonionic surfactant is present in a total amount of from about 0.01 wt% to about 0.2 wt%.

[0099] In some embodiments, based on the weight of the composition, at least one polyglyceryl nonionic surfactant comprises polyglyceryl-6 caprylate present at about 0.025 wt% and polyglyceryl didecanoate present at about 0.025 wt%.

[0100] In some embodiments, each of at least one nonionic surfactant in the makeup removing composition is present in an amount of from about 0.01 wt% to about 1 wt%, or from about 0.01 wt% to about 0.2 wt%, or from about 0.02 wt% to about 0.03 wt%, or any suitable combination, sub-combination, range or sub-range, based on the weight of the makeup removing composition. However, those of ordinary skill in the art will appreciate that other ranges are within the scope of the present invention.

[0101] Thus, each of at least one nonionic surfactant is present in an amount of from about 0.01 wt%, 0.015 wt%, 0.02 wt%, 0.025 wt%, 0.03 wt%, 0.035 wt%, 0.04 wt%, 0.045 wt%, 0.05 wt%, 0.055 wt%, 0.06 wt%, 0.065 wt%, 0.07 wt%, 0.075 wt%, 0.08 wt%, 0.085 wt%, 0.09 wt%, 0.095 wt%, 0.1 wt%, 0.2 wt%, 0.3 wt%, 0.4 wt%, 0.5 wt%, 0.6 wt%, 0.7 wt%, 0.8 wt%, 0.9 wt% to about 1.0 wt% (including increments and ranges therein and therebetween), based on the total weight of the makeup removing composition.

[0102] (v) Water

[0103] According to various embodiments, water is present in the makeup removing composition in an amount of from about 30 wt% to about 70 wt%, or from about 35 wt% to about 65 wt%, or from about 40 wt% to about 60 wt%, or from about 45 wt% to about 55 wt%, or about 50 wt%, or any suitable combination, sub-combination, range or sub-range, based on the weight of the makeup removing composition. However, those of ordinary skill in the art will appreciate that other ranges are within the scope of the present invention. Thus, water is present in an amount of from about 30 wt%, 35 wt%, 40 wt%, 45 wt%, 50 wt%, 55 wt%, 60 wt%, 65 wt% to about 70 wt% (including increments and ranges therein and therebetween), based on the total weight of the makeup removing composition.

[0104] The water used may be sterile demineralized water; and / or floral water, such as rose water, cornflower water, chamomile water or lime water; and / or natural thermal water or mineral water, such as: water from Vittel, water from the Vichy basin, water from Uriage, water from La Roche Posay, water from La Bourboule, water from Enghien-les-Bains, water from Saint Gervais-les-Bains, water from Neris-le s-Bains, water from Allevar-les-Bains, water from Digne, water from Maizieres, water from Neyrac-les-Bains, water from Lons-le-Saunier, water from Eaux Bonnes, water from Rochefort, water from Saint Christau, water from Les Fumades, water from Tercis-les-Bains or water from Aven e. The aqueous phase may also contain reconstituted thermal water, i.e., water having the characteristics of reconstituted thermal water containing trace elements such as zinc, copper, magnesium.

[0105] There is no limitation on the pH value of the makeup removing composition, but it is generally from 2 to 12, and in some embodiments is one of 3 to 11, 5 to 9 and 6 to 8, and in some embodiments is 7. In some specific embodiments, the pH of the makeup removing composition is from about pH 4 to about pH 7. The pH value can be adjusted to the desired value by adding a base (organic or inorganic), such as ammonia or a primary (poly)amine, secondary (poly)amine or tertiary (poly)amine, such as monoethanolamine, diethanolamine, triethanolamine, isopropanolamine or 1,3-propanediamine, or alternatively by adding an inorganic acid or an organic acid, advantageously a carboxylic acid, such as citric acid.

[0106] In some embodiments, the makeup removing composition does not contain alcohols, such as monohydric alcohols, such as monohydroxy C1-C8 alcohols, such as ethanol, propanol, butanol, isopropanol, isobutanol and benzyl alcohol and phenethyl alcohol.

[0107] Optional component

[0108] In some embodiments, one or more active substances may be present in the cosmetic composition according to the present disclosure, and the additives are selected from, for example, preservatives / antimicrobials (e.g., chlorphenesin, salicylic acid, phenoxyethanol, potassium sorbate, and caprylyl glycol); active substances (e.g., hydroxyacetophenone); vitamins (e.g., vitamin A, β-carotene, tocopherol / vitamin E, panthenol, retinol, resveratrol, vitamin C, niacinamide, their derivatives, and combinations thereof); hyaluronic acid in the form of hydrolyzed hyaluronic acid or sodium hyaluronate; coloring materials / pigments; essential oils; antioxidants (phenolic compounds such as chalcones, flavonoids, flavanones, flavanols, flavonols, dihydroflavonols, isoflavonoids, neoflavonoids, catechols, anthocyanins, tannins, lignans, aurones, stilbenoids, curcuminoids, alkylphenols, betalains, capsinoids, hydroxybenzophenones, methoxyphenols, naphthoquinones, and phenoterpenes, resveratrol, curcumin, pinoresinol, ferulic acid, hydroxytyrosol, cinnamic acid, caffeic acid, p-coumaric acid, baicalin (Scutellaria root extract), pine bark extract (coastal pine bark / bud extract), ellagic acid); vitamins and vitamin derivatives such as calcium pantothenate, tocopherol, and ascorbic acid; hydroxy acids; citric acid, sodium citrate, sodium chloride; neutralizing agents, chelating agents, or pH regulators (e.g., triethylamine (TEA), trisodium ethylenediaminedisuccinate, EDTA, and sodium hydroxide); powders, fragrances, dyes, pigments; organic or mineral ultraviolet filters; and combinations thereof.

[0109] In some specific embodiments, the composition according to the present disclosure may comprise one or a combination of additives selected from the following: sodium hydroxide, panthenol, hydroxyacetophenone, gluconolactone, myristyl trimethyl ammonium bromide, sodium citrate, sodium chloride, dicaprylyl ether, citric acid, or combinations thereof.

[0110] Although the above-mentioned optional components are given as examples, it will be understood that other optional components compatible with cosmetic applications known in the art may be used.

[0111] According to various embodiments, when present in a composition according to the present disclosure, the amount of one or more active substances and additives, alone or in combination, can be from about 0.0001 wt% to about 20 wt%, based on the total weight of the composition, and in some embodiments from about 0.005 wt% to about 0.01 wt%, and in some embodiments from about 0.01 wt% to about 0.1 wt%, and in some embodiments from about 0.15 wt% to about 5 wt%, and in some embodiments from about 0.40 wt% to about 4 wt%, and in some embodiments from about 0.5 wt% to about 2.5 wt%, and in some embodiments from about 0.1 wt% to about 0.5 wt%, and in some embodiments from about 1 wt% to about 2 wt%, or any suitable combination, sub-combination, range, or sub-range thereof. However, those of ordinary skill in the art will understand that other ranges are within the scope of the present invention.

[0112] Thus, any one or a combination of the active substances and additives can be present, each or the combination being present in an amount from about 0.0001 wt%, 0.0005 wt%, 0.001 wt%, 0.002 wt%, 0.003 wt%, 0.004 wt%, 0.005 wt%, 0.006 wt%, 0.007 wt%, 0.008 wt%, 0.009 wt%, 0.01 wt%, 0.02 wt%, 0.03 wt%, 0.04 wt%, 0.05 wt%, 0.06 wt%, 0.07 wt%, 0.08 wt%, 0.09 wt%, 0.10 wt%, 0.20 wt%, 0.30 wt%, 0.40 wt%, 0.50 wt%, 0.60 wt%, 0.70 wt%, 0.80 wt%, 0.90 wt%, 1.0 wt%, 2 wt%, 3 wt%, 4 wt%, 5 wt%, 6 wt%, 7 wt%, 8 wt%, 9 wt%, 10 wt%, 11 wt%, 12 wt%, 13 wt%, 14 wt%, 15 wt%, 16 wt%, 17 wt%, 18 wt%, 19 wt% to about 20 wt% (including increments and ranges therein and therebetween).

[0113] Product / manufactured article

[0114] The present invention also relates to a cosmetic comprising a makeup removing composition according to the present invention. The product according to the present invention comprises a makeup removing composition according to the present invention and a container or packaging containing the makeup removing composition.

[0115] The makeup remover composition of the present invention is sprayable, or in other words, capable of being dispensed in the form of fine particles or a mist. This means using a dispenser with a spray nozzle to contain and dispense the makeup remover composition, which in some embodiments is a high-precision spray nozzle capable of delivering a mist of particles (droplets) having a micron size or average size in the range of about 10 microns to about 900 microns or about 40 microns to about 300 microns or about 80 to about 100 microns.

[0116] Accordingly, the present invention also relates to a product comprising a container and a spray nozzle, wherein the container contains the makeup remover composition of the present invention.

[0117] The makeup remover composition of the present invention can be adapted to any container having a spraying device, including suitable aerosol spraying devices, most preferably non-aerosol spraying devices. Thus, non-aerosol spraying devices are preferred and include, for example, atomizing pumps or spray pumps such as the following pumps: Eurogel spray pump (available from Seqquist Perfect, Cary Ill.), PI spray pump (available from Precision, Ajax, Canada), APTAR oil mist pump, [Rare Beauty] atomizing pump, Calmar spray pump (Calmar, Inc., City of Industry, Calif) and Mitani atomizing pump (available from MITANI VALVECO., LTD).

[0118] In a specific embodiment of the present invention, the present disclosure provides a product comprising: a container containing the makeup remover composition according to the present invention; an outlet connected to the container, such as the outlet of a spray nozzle; and a spraying device, wherein the spraying device is capable of releasing the makeup remover composition in the container via the outlet, wherein the spray nozzle is a fine mist nozzle that delivers a pumping volume of the mist of about 0.02 ml (about 0.01 to about 1.0 ml / pump) and has particles (droplets) having a micron size or average size in the range of about 10 microns to about 900 microns or about 40 microns to about 300 microns or about 80 to about 100 microns. In some such embodiments, the makeup remover composition contained in the container is transparent or translucent, where the term "translucent" refers to the property of a material that allows light to pass through a 5 mm thick sample without being able to distinguish alphanumeric characters, and the term "transparent" refers to the property of a material that allows light to pass through a 5 mm thick sample and is able to distinguish alphanumeric characters. In some specific embodiments, the atomized droplets are also transparent or translucent.

[0119] The following examples according to the present invention are given by way of illustration and are not limiting. The names are chemical names or INCI names. Unless otherwise mentioned, the amounts are given therein in weight %.

[0120] Example

[0121] Example 1: Raw materials

[0122] Table 1: Raw Materials

[0123] INCI name Water Isocetane Isododecane Isopropyl myristate Polyglyceryl-6 caprylate Polyglyceryl didodecanoate Hydroxyethyl cellulose

[0124] Example 2: Composition of the present invention:

[0125] Various representative embodiments of the compositions of the present invention are illustrated herein by way of example.

[0126] Table 2: Composition Ingredients of the Present Invention

[0127] Invention 1 INCI US Isopropyl myristate* Sodium hydroxide Panthenol Water Sodium citrate Hydroxyethyl cellulose Triethyl citrate* Sodium chloride Isocetane* Isododecane* Dioctyl ether Polyglyceryl-6 didodecanoate* Hydroxyacetophenone Polyglyceryl-6 caprylate* Glucono delta-lactone Myristyl trimethyl ammonium bromide Citric acid

[0128] Table 3: Compositions of the Present Invention (Water / Oil Ratio Changed), wherein the water-to-oil ratio of INV 1 (also known as INV 1) is about 50 / 50, and each VAR embodiment has a different water-to-oil ratio as exemplified and further shown in Example 4.

[0129]

[0130] Table 4: Compositions of the Present Invention (Continued; Water / Oil Ratio Changed)

[0131]

[0132]

[0133] Example 3: Comparative Composition #1

[0134] Table 5: Comparative Compositions

[0135] INCI US (AEROSOL) Ethyl trisiloxane Isododecane Cyclopentasiloxane Cetyl ethylhexanoate Isoamyl cocoate Isopropyl isostearate Isostearyl isostearate Jojoba (SIMMONDSIA CHINENSIS) seed oil Rosa rubiginosa seed oil Fragrance / flavor

[0136] Table 6: Comparative Composition #2

[0137]

[0138]

[0139] Table 7: Comparative Composition #3

[0140] INCI US (NOT SPRAY) Water (WATER / AQUA) Cyclopentasiloxane Isocetane Potassium phosphate Sodium chloride Hexylene glycol Dipotassium hydrogen phosphate Disodium EDTA Decyl glucoside Polyaminopropyl biguanide

[0141] Table 8: Comparative Composition #6

[0142] INCI US Cyclopentasiloxane Octyl polymethylsiloxane Tocopheryl acetate

[0143] Table 9: Comparative Composition #5

[0144] INCI US (AEROSOL) Caprylic / capric triglyceride C12-15 alkyl benzoate Butane Isobutane Propane Tocopheryl acetate

[0145] Table 10: Comparative Composition #7

[0146]

[0147]

[0148] Example 4: Demonstration of the Spraying and Sensory Characteristics of Different Water-to-Oil Ratios of the Invention

[0149] Table 11: Jetting Test & Sensory Test of Different O / W & Spraying Modes from 10:90 to 90:10

[0150]

[0151] Example 5: Demonstration of Makeup Removing with Different Water-to-Oil Ratios

[0152] Table 12: Different O / W & Mascara and Foundation Removal Tests from 10:90 to 90:10 (Comparing the Number of Rounds Required to Reach Cleanliness)

[0153]

[0154] Example 6: Stability Demonstration

[0155] Table 13: Stability Test

[0156]

[0157] Example 7: Osmotic Pressure Test

[0158] Table 14: Osmotic Pressure

[0159]

[0160] The osmotic pressure of the aqueous phase was tested according to Var 9, where the aqueous phase also contained a colorant, a fragrance, and 0.02% hydroxyethyl cellulose. Briefly, the equipment used included an automatic osmometer: OSK 40BU201 (Ogawa-seiki), and the test protocol included preparing the composition; shaking 20 times and allowing to stand for at least 8 hours (e.g., overnight); extracting the aqueous phase and measuring the osmotic pressure with an osmometer (unit of measurement: mOsm / l, number of molecules per liter of test material).

[0161] Therefore, there is a close transfer relationship between the tested compositions and Var 9 and INV 1 (the latter two only vary in oil / water concentration). It is understood in the art that based on the knowledge that the osmotic pressure value of tears is in the range of 260 - 290 and the closer the osmotic pressure (mOsm / l) of the product is to this range, the milder the product is to the eyes, the osmotic pressure can be used as an indirect way to evaluate whether the preparation may be irritating to the eyes. Therefore, since the value of 315 mOsm / l is close to the osmotic pressure of tears, it is concluded empirically that the listed preparations are suitable for use as eye makeup removers around the eyes without causing discomfort. These results have been confirmed in clinical studies, which have shown that the study subjects did not report skin irritation or mention any eye irritation. According to various embodiments, the osmotic pressure is from about 260 to about 350 mOsm / l, and in some embodiments from about 300 to about 330 mOsm / l.

[0162] Although consumer tests have shown that the compositions of the present invention are generally non-irritating to the skin and eyes, this osmotic pressure test more specifically shows whether it is mild to the eyes, which is a key part of the makeup removal process.

[0163] Example 8: CMC surface tension test

[0164] Using Var 9 of the present invention, the critical micelle concentration was evaluated to demonstrate the concentration of surfactant in the bulk phase above which aggregates of surfactant molecules, micelles, begin to form. The measurement of CMC surface tension was carried out on a tensiometer. Now referring to Figure 1 , the curve shows a decrease in the slope of the surface tension, enters a plateau and the surface tension becomes constant. The intersection of the decreasing slope and the surface tension plateau indicates the presence of micelles. The shape of the curve demonstrates that the aqueous phase of the present invention 1 tested is micellar.

[0165] Example 9: In vitro study: Evaluation of the effect of makeup removal dissolving atomizing spray on skin barrier function in vitro using biophysical tests and zein protein model

[0166] The purpose of this experiment was to demonstrate the effect of the makeup remover on stratum corneum (SC) lipids and proteins, and to demonstrate the effect of different formulation components (i.e., surfactants, humectants, etc.) on the mildness potential of the cleanser.

[0167] This study also demonstrated the performance of the compositions of the present invention (INV 1) in DSC, TEWL and zein tests.

[0168] The mildness of the makeup removal dissolving atomizing spray INV 1 was evaluated in vitro. In summary, INV 1 falls within the target mildness region (roughly delimited by the light green rectangle), where it neither disturbs lipids (DSC) nor increases water loss (TEWL).

[0169] Permeation of water vapor through the SC (in vitro TEWL)

[0170] The surface of the SC sample was cleaned with isooctane and placed in the sample holder for TEWL. The sample holder was then immersed in Evian water to wet the SC and dried in the ambient atmosphere for at least 1 hour. The surface of the SC sample was pre-wetted with a mixture solution of 10 μl of water and n-propanol (8:2) per sample, and then conditioned in a glove box under a controlled atmosphere (30 °C, 30% RH) for 8 hours. The control TEWL measurement value "T0" was recorded. Then the SC sample was immersed in a detergent formulation diluted 4-fold (25%) with water for 2 hours, gently stirred on a shaker, washed three times in succession with water rinses, and the sample was left at room temperature for at least 4 hours to ensure drying. Then the SC sample was placed in a temperature and humidity control chamber and equilibrated at 30 °C and 30% RH. After equilibration overnight, the TEWL measurement value "T1" was recorded.

[0171] Measure the water flow through the SC sample located above the water tank. The measurement was carried out in a glove box maintained at 30 °C and 30% RH using a hygrometry probe connected to a robotic sample holder and a data acquisition system Dermalab. The hygrometry probe includes two humidity sensors at different heights in a cylindrical probe chamber, so that the humidity gradient can be measured and used to calculate the flux of water vapor. The measurements were carried out before and after processing each sample, so each sample served as its own control to ensure robust measurements.

[0172] Reference Figure 2 And Table 15, which provides the test results shown below. Due to the high inherent variability of the SC matrix, the results are expressed as the relative change in TEWL for each sample: Δ(TEWL) = (T1 - T0) / T0 × 100%. A positive change corresponds to a diffusion effect (weakening of the barrier function), and a negative value corresponds to an occlusion effect. The average value is represented by an open square for reference.

[0173] Evaluation of intercellular SC lipid disorder by DSC

[0174] After the TEWL measurement, the same samples were used for DSC analysis after re-equilibration at 75% RH and 25 °C for 4 hours.

[0175] The DSC pan was placed on an analytical balance and weighed. The SC sample was removed from the glove box / temperature and humidity chamber and the sample was removed from the sample holder. Two pieces of SC were rolled together and placed in the weighed DSC pan and sealed using a press. The weight of the DSC pan was recorded and subjected to DSC analysis.

[0176] Measurements were carried out using an aluminum-sealed pan, heating from 10 °C to 110 °C at a rate of 5 °C / min.

[0177] Reference Figure 2 and Table 15, which provides the test results as shown below. The linear combination of the measured displacements of the T2 and T3 transitions for each treatment was used as the measure of post-treatment SC lipid disorder: ΔT 有效值 = 0.7ΔT m (T2) + 0.3ΔT m (T2). The T2 transition was given a higher weight because, by accepted understanding, it is the primary criterion for lipid disorder; the contribution of T3 was also included.

[0178] Protein solubility was evaluated by the zein test

[0179] The irritation of surfactants was evaluated by using the zein solubility test, where zein is a yellow corn protein similar to keratin present in the skin, has limited solubility in water, and is denatured (dissolved) by surfactants. The ability of surfactants to denature and dissolve zein is related to their skin irritation potential. Soluble zein was measured using a spectrophotometer by the modified Lowry method. Absorbance is related to the solubility of zein and can thus be considered as a measure of the irritation potential or irritancy of the product. The irritation of the analyzed samples was graded, and a 1.5% sodium lauryl sulfate (SLS) solution was used as a positive control for comparison. The irritation data of the samples were expressed as a percentage of the SLS score.

[0180] The percentage of zein score calculated for the corresponding blank is provided in Table 15 below. The ranking of the samples based on the irritation (zein score %) analyzed relative to SLS is shown in Figure 2 . Now refer to Figure 2 , which shows that the zein score is a function of the DSC and TEWL scores, as explained above. The zein score for Invention 1 was 48, just below the cusp of strong protein denaturation and falling into the upper right corner of the plotted rectangle, indicating that it is within the range considered a mild formulation. The zein scores for the compositions according to the present disclosure were from about 88 to about 13, which was accomplished by using the surfactants according to the present disclosure and avoiding irritating surfactants that would cause lipid disorder and high zein solubility.

[0181] A cleaner map was plotted based on three mildness tests

[0182] The results of the three above-mentioned tests (TEWL, DSC, and zein) can be conveniently combined in a single graph to visually represent the performance of each formulation based on these three metrics. In the following graph, the abscissa shows the effect on the barrier property related to water penetration (TEWL), and the ordinate shows the effect on lipid order (DSC). The light green rectangle corresponds to the target mildness region where neither SC penetration nor lipid disorder occurs. The zein score is represented by the color of the data points, with a red shade indicating a high score (strong protein dissolution / denaturation) and a green shade indicating a low score (little protein dissolution / denaturation).

[0183] Table 15: Mildness Test Score

[0184]

[0185] Example 10: Clinical Study: Study A

[0186] A clinical study was conducted to compare the makeup remover of the present invention with a commercially available benchmark and other commercially available spray and non-spray makeup removers.

[0187] Clinical Study A: Comparison 1 is a continuous mist that glides over the skin and immediately dissolves all makeup upon contact without leaving the skin feeling tight or dry. This droplet-free, ultra-fine mist is the secret of Comparison 1 to easily remove full makeup. The formulation has calming jojoba and brightening rosehip oil to soothe the skin, and the fragrance notes of green tea, cucumber, and rose to refresh the skin. The composition of the present invention was evaluated relative to this competitive benchmark.

[0188] Method ■ Blind sequential univariate design ■ 2 products ■ INV 1 ■ Comparison 1 ■ Recruited online and arranged in person ■ Used for 5 days, with online surveys and videos taken after using each product

[0189] Recruitment criteria ■ N = 37, women ■ Age 18 - 55 years old ■ Current users remove makeup 5 days or more per week – in any form ■ Cannot use only makeup removal wipes ■ Must be a user of waterproof mascara (can be a dual user, but agrees to use WP for 10 days), and long-lasting foundation and / or lipstick ■ Willing to use spray makeup remover ■ Users in the mass and / or luxury markets ■ All skin types: oily, dry, normal, combination ■ All skin tones ■ All ethnicities ■ Standard safety screening

[0190] Exclusions: ■ Users who only use makeup removal wipes ■ Allergies or known sensitivity to skin care products or cosmetics ■ Currently receiving care from a facial dermatologist ■ Very / extremely sensitive skin and eyes ■ Prone to severe acne ■ Have had facial surgery in the past 3 months ■ Pregnancy or lactation

[0191] Test: INV 1 relative to Comparison 1: ReferenceFigure 3 This graph details the consumer's sensory experience journey and reports the overall feeling based on the tests conducted in the above-mentioned clinical study. The specific data points are described in Table 16.

[0192] Referring again to Figure 3 it is noted that there are significant differences in the amount and nature of the oil content in these compositions. Comparison 1 is anhydrous, containing silicone oil / silicone and a strong surfactant. INV 1 shows an overall satisfactory user experience journey, with the opportunity to improve the amount of rubbing required for complete removal. Comparison 1 is similar to INV 1 before and during the use journey. However, Comparison 1 is less satisfactory and less popular after use because it makes the skin feel clean, leaves no residue, and requires washing the face after application, which is unusual.

[0193] As shown, INV 1 is superior to Comparison 1 in terms of product consistency and shows a very large advantage in the post-use feeling. Consumers prefer this product over the top benchmark Comparison 1 because the formulation INV 1 of the present invention has a clean appearance, makes the skin feel comfortable (no face washing is required afterwards), and is gentle on the face.

[0194] Users consider both products to be effective, gentle on the skin, and provide a quick removal method. It is worth noting that although the overall performance of the present invention and the comparison is proven to be comparable, the main benefit of the present invention is the surprisingly effective removal in a water-based composition that does not require rinsing after use but leaves the skin without a greasy or oily feeling.

[0195] Table 16: User Qualitative Experience Journey (corresponding to Figure 3 )

[0196]

[0197]

[0198] Example 11: Clinical Study B: Mascara Removal; Evaluation of Removal Effect

[0199] Comparison 1 and INV 1 were evaluated. The target N = 18 white female volunteers; aged 18 - 60 years, medium to long eyelashes, no drooping eyelids, and the test product was Maybelline Colossal Big Shot Ultra Black Waterproof Mascara.

[0200] All subjects applied the cosmetics in the same manner according to a standard procedure including prior cleansing. The removal of mascara for all subjects was completed through the same standard procedure.

[0201] The invention 1 mentioned in this embodiment contains the same preparation in a specific package (SP).

[0202] The different actuators result in a great difference in the volunteers' experience. Comparison 1 (aerosol spray) is a light mist that looks as if nothing has been applied to the face. Sometimes, the volunteers even ask if there is anything. INV 1 has a stronger wetting effect during application. The subjects can feel the product on their faces, indicating that it is delivered to the skin.

[0203] Dry - hand emulsification is the key to making the spray makeup remover work best. After making the first round of circular motions around the eyelashes, it is obvious that the product decomposes immediately. Comparison 1 spray decomposes slightly faster due to the amount of oil in it. The two products look and are reported to feel different on the skin. Comparison 1 has an oily feeling / oily appearance on the face. Due to the large mist, oily particles are left around the hairline, making the hair greasy (which may or may not be acceptable to consumers). Once applied, INV 1 has a very wet appearance, decomposes easily during emulsification, is easily removed overall, and has very little resistance on the eyelashes during removal with a cotton pad because the product itself does not slide much (not noticed by consumers).

[0204] In summary, when emulsified with dry hands, both makeup remover sprays perform efficiently. Comparison 1 performs slightly better than the market - leading Comparison 2. INV 1 performs similarly to Comparison 2 and Comparison 3. The biphasic and spray formulations use different removal methods. However, in general, both products are highly efficient waterproof mascara removers.

[0205] Table 17: Mascara removal with the present invention compared to comparative products

[0206]

[0207] Example 12: Clinical study C: Mascara removal; Evaluation of removal effect

[0208] Tests were conducted to demonstrate the performance of the new packaging options of INV 1. The target N = 6 white female volunteers; aged 18 - 60 years, medium - long eyelashes, no drooping eyelids, test products INV 1, INV 1CP, and Comparisons 1 - 7, and Maybelline Colossal Big Shot ultra - black waterproof mascara.

[0209] The invention 1 mentioned in this embodiment includes the same preparation in different packages (SP and CP).

[0210] According to the standard procedure including prior cleansing, all subjects applied cosmetics in the same way. The mascara removal for all subjects was completed through the same standard procedure.

[0211] In summary, compared to the original prototype makeup remover INV 1CP, the makeup removing effect of INV 1 with a spray device similar to Inv 8 is much lower. The original prototype is a highly efficient heavy makeup mascara remover. However, after INV 1 replaced the pump, the efficiency dropped to a medium level. The formula is the same, but the impact of the amount of product sprayed onto the target area is different. The pump of INV 1 sprays everywhere around the face, but it is not close enough to the eyes to achieve proper saturation for removal, so the effect is lower. Two competing products, Inv 5 and 6 makeup remover sprays, perform like medium to highly efficient heavy makeup mascara removers. Inv 8 is slightly more efficient than Inv 7, with a difference of 1 makeup remover cotton (median).

[0212] Table 18: Mascara removal of the present invention with alternative pump forms compared to comparative products

[0213]

[0214] Example 13: Clinical Study D: Mascara removal; Evaluation of removal effect

[0215] Tests were conducted to demonstrate the performance of new packaging options of INV 1 with specific different actuators (CP, HDM, and OP). The target N = 6 white female volunteers; aged 18 - 60 years, medium to long eyelashes, no drooping eyelids, test products INV 1, INV 1CP, INV1HDM, and INV1OP, and comparisons 1 - 7.

[0216] The invention 1 mentioned in this example includes the same preparation in different packages (SP, CP, HDM, and OM).

[0217] According to the standard procedure including prior cleaning, all subjects applied cosmetics in the same way. The mascara removal of all subjects was completed through the same standard procedure.

[0218] In summary, when emulsified with dry hands, both makeup remover sprays perform efficiently. Comparison 1 performs slightly better than the market - leading makeup remover Comparison 2. The 2 test formulas (INV 1HDM & INV 1OM) perform similarly to the biphasic products Comparison 2 and Comparison 3. The biphasic and spray formulations use different removal methods. However, in general, both products are highly efficient waterproof mascara removers.

[0219] Table 19: Mascara removal of the present invention compared to comparative products (approx. 0.2 g / spray)

[0220]

[0221] These results provide evidence that the fine mist spray packaging produces the same high efficiency in a biphasic composition having an aqueous phase and an oil phase as a competing product (Comparison 1) having a 100% oil composition.

[0222] Example 14: Clinical Study E: Evaluation of the atomizing spray pump container of the present invention (INV 1) relative to a reference aerosol (Comparison 1) (propellant-based) spray

[0223] A study was conducted to explore consumers' feelings and preferences for the formulation and packaging by evaluating the entire product experience journey, including application, texture, feel, final appearance, durability, and removal.

[0224] Method: A 14-day home use test was conducted; 42 female users aged 18 - 30 years, with a mix of different ethnicities, skin types, and skin tones, users of both mass and luxury brand cosmetics had a 4-day active period, and the INV1 and Comparison 1 products were tested in two consumer markets using a randomized sequential one-way design; a product usage protocol was provided, including specific instructions for product application, makeup, and mascara removal; the subjects provided responses to questions regarding product application and sensory experience.

[0225] The results are listed in Table 20 below.

[0226] Test: INV 1 relative to Comparison 1: Reference Figure 4 , and the chart details the experience journey of consumers using the dispensing atomizing pump of INV 1 and the aerosol spray device of Comparison 1.

[0227] Refer again to Figure 4 , noting that there are significant differences in the amount and nature of the oil content in these compositions, where Comparison 1 is anhydrous, including silicone oil / silicone and strong surfactants, and INV 1 dispensed in the atomizing pump showed an overall satisfactory user experience, and both products showed opportunities for improvement in the initial oily feel on the face and on the skin upon direct application.

[0228] Users found both products to be effective, gentle on the skin, and provided a quick removal method. Notably, the overall performance of the present invention and the comparative dispensing containers was proven to be comparable, and the main benefit of the present invention is the elimination of the use of aerosol propellants and an overall reduction in the use of silicone and surfactants without compromising effectiveness.

[0229] Table 20: Qualitative experience journey of user product applicators

[0230]

[0231] While the present disclosure has been described with reference to preferred embodiments, those skilled in the art will understand that various changes can be made and equivalents can be substituted for elements of the present disclosure without departing from the scope of the present disclosure. In addition, many modifications can be made to adapt a particular situation or material to the teachings of the present disclosure without departing from the basic scope thereof. Therefore, it is intended that the present disclosure not be limited to the particular embodiments disclosed as the best mode contemplated for carrying out the present disclosure, and that the present disclosure will include all embodiments falling within the scope of the appended claims.

[0232] As used herein, the article "a / an" when applied to any feature of the embodiments of the present disclosure described in the specification and claims means one or more. The use of "a / an" does not limit the meaning to a single feature unless such a limitation is specifically stated. The article "the" preceding a singular or plural noun or noun phrase indicates one or more specifically specified features and can have a singular or plural meaning depending on the context in which it is used. The adjective "any" means, without selection, any number of one, some, or all.

[0233] As used herein, "at least one" means one or more, and thus includes individual components as well as mixtures / combinations.

[0234] When used in the appended claims in their original and amended forms, the transitional terms "comprising", "consisting essentially of", and "consisting of" define the scope of the claim with respect to the exclusion of additional claim elements or steps (if any) not recited. The term "comprising" is intended to be inclusive or open-ended and does not exclude any additional, unrecited elements, methods, steps, or materials. The term "consisting of" excludes any element, step, or material other than those specified in the claim, and in the latter case, excludes impurities normally associated with the specified materials. The term "consisting essentially of" limits the scope of the claim to the specified elements, steps, or materials and those that do not materially affect the basic and novel features of the claimed disclosure. In alternative embodiments, all materials and methods embodying the present disclosure described herein can be more specifically defined by any one of the transitional terms "comprising", "consisting essentially of", and "consisting of".

[0235] In some embodiments, the terms "excluding", "free of", and "substantially free of" mean that, based on the total weight of the makeup removing composition, there is no reliably measurable excluded substance (usually 0% by weight) in the makeup removing composition; or, for example, based on the total weight of the makeup removing composition, there is no amount greater than about 5% by weight of any excluded substance as described herein. The terms "excluding", "free of", and "substantially free of" mean that while it is preferred that there be no excluded substances in the makeup removing composition, there may be very small amounts of excluded substances in the makeup removing composition of the present invention, provided that these amounts do not substantially affect the advantageous properties of the makeup removing composition. In particular, the terms "excluding", "free of", and "substantially free of" mean that, based on the total weight of the makeup removing composition, the substance may be present in the makeup removing composition in an amount less than 5% by weight, or less than 4% by weight, or less than 3% by weight, or less than 2% by weight, or less than 1% by weight, or less than 0.1% by weight.According to various embodiments, some or all of the following ingredients may be excluded from the makeup removing composition according to the present invention: alcohols, such as but not limited to monohydric alcohols; powders including nylon-12, polymethyl methacrylate, polyethylene beads, and powders considered to be microplastics; lactic acid, glycolic acid, tartaric acid, mandelic acid, citric acid, salicylic acid and their derivatives (including 5-n-octanoyl salicylic acid, salicylates, sodium salicylate and willow bark extract), octanoyl salicylic acid, β-hydroxybutyric acid, propionic acid, β-hydroxy-β-methylbutyric acid, carnitine tropate and tresca acid; alkyl glycosides selected from the group consisting of: decyl glucoside, lauryl glucoside, octyl glucoside, cocoyl glucoside, octyl / decyl glucoside and sodium methyl glucoside and combinations thereof; surfactants of C10–C20 fatty alcohol or fatty acid hydrophobes condensed with about 2 to about 100 moles of ethylene oxide or propylene oxide per mole of hydrophobe; C2-C10 alkyl phenols condensed with 2 to 20 moles of alkylene oxide; ethylene glycol mono- and di-fatty acid esters; glycerol monofatty acid esters; sorbitan; mono- and di-C8-C20 fatty acids; polyoxyethylene sorbitan; alkyl glycosides and sugar fatty acid amides (e.g., methyl glucamide); alkyl ether sulfates / esters and sulfonates / esters; alkyl sulfates / esters and sulfonates / esters; alkyl benzene sulfonates / esters; alkyl and dialkyl sulfosuccinates / esters; C8–C20 acyl hydroxyethane sulfonates / esters; C8–C20 alkyl ether phosphates / esters; alkyl ether carboxylates / esters, PEG-100 stearate; PEG-20 stearate and other ethers of poly(ethylene glycol); polyethylene glycol (PEG) surfactants, polypropylene glycol (PPG) surfactants, sulfate surfactants; taurates, such as taurate surfactants; sucrose stearate and other sugar ester-based emulsifiers; glycerol stearate and other glycerol esters; ethyldicocamide PEG-15 disodium sulfate; sodium stearoyl glutamate and other fatty acid amides; Steareth-100 and other fatty ethers, cationic surfactants and other cationic compounds; silicones, such as silicone polymers, silicone elastomers and silicone oils, for example selected from dimethicone, cyclopentasiloxane, cyclohexasiloxane and combinations thereof; phthalates, parabens, sulfates / esters, polyquaternium, microplastics, synthetic dyes, gelling agents and combinations thereof.

[0236] Except in the operating examples, or where otherwise indicated, all numbers expressing amounts of ingredients and / or reaction conditions are to be understood as being modified in all instances by the term “about,” which means within 10% of the indicated number (e.g., “about 10%” means 9% to 11%, and “about 2%” means 1.8% to 2.2%).

[0237] Unless otherwise indicated, all percentages and ratios are by weight. Unless otherwise indicated, all percentages are based on the total composition. In general, unless otherwise expressly stated herein, the "weight" or "amount" of a percentage amount relative to an ingredient as used herein refers to the amount of the raw material including said ingredient, where the raw material may be described herein as including less than or up to 100% active of said ingredient. Thus, the weight percentage of the active substance in the composition represents the amount of the raw material containing the active substance used, and may or may not reflect the final percentage of the active substance, where the final percentage of the active substance depends on the weight percentage of the active substance in the raw material.

[0238] All ranges and amounts given herein are intended to include sub-ranges and amounts using any of the disclosed points as endpoints. Thus, a range of "1% to 10%, such as 2% to 8%, such as 3% to 5%" is intended to cover "1% to 8%", "1% to 5%", "2% to 10%", etc. All numbers, amounts, ranges, etc. are intended to be modified by the term "about", whether or not so expressly stated. Similarly, a range of "about 1% to 10%" given is intended to have the term "about" modify the 1% and 10% endpoints. In addition, it should be understood that when an amount of a component is given, unless otherwise specifically stated, it is intended to represent the amount of the active material.

[0239] Although the numerical ranges and parameters setting forth the broad scope of this disclosure are approximations, the numerical values set forth in the specific examples are reported as accurately as possible unless otherwise indicated. However, any numerical value inherently contains certain errors necessarily resulting from the standard deviations found in their respective testing measurements. The following examples are illustrative of the embodiments of this disclosure and are not restrictive in nature.

[0240] All publications and patent applications cited in this specification are incorporated herein by reference and, for any and all purposes, as if each individual publication or patent application were specifically and individually indicated to be incorporated by reference. If there is any inconsistency between this disclosure and any publication or patent application incorporated herein by reference, then this disclosure shall govern.

Claims

1. A makeup removing composition, comprising: a biphasic micellar system comprising an oil phase and an aqueous phase, said system comprising: a. An oil blend, comprising iii. One or more branched or straight-chain liquid alkanes having a carbon chain length of C11 to C20, comprising isocetane and isododecane, and iv. One or more emollient esters; b. At least one polymeric thickener for aqueous systems; c. At least one polyglycerol nonionic surfactant; and d. Water present in an amount of about 30% to about 70% by weight of the makeup removing composition; wherein the composition is a micellar biphasic system, wherein water and oil are present in a water-to-oil ratio of about 1.5:1 to about 1:1.

5.

2. The makeup removing composition according to claim 1, wherein the composition does not comprise one or more of silicone, alcohols, sulfate-containing compounds, PEG surfactants, xanthan gum, or combinations thereof.

3. The makeup removing composition according to claim 1, wherein the one or more emollient esters comprise isopropyl myristate, and the at least one polymeric thickener for aqueous systems comprises hydroxyethyl cellulose.

4. The makeup removing composition according to claim 1, wherein, based on the weight of the makeup removing composition, isocetane is present in an amount of about 15% to about 30% by weight, and isododecane is present in an amount of about 10% to about 20% by weight.

5. The makeup removing composition according to claim 1, wherein, based on the weight of the makeup removing composition, isocetane is present in an amount of about 28% by weight, and isododecane is present in an amount of about 15% by weight.

6. The makeup removing composition according to claim 1, wherein, based on the weight of the makeup removing composition, the one or more emollient esters are present in an amount of about 1% to about 8% by weight.

7. The makeup removing composition according to claim 1, wherein, based on the weight of the makeup removing composition, the one or more emollient esters comprise isopropyl myristate present in an amount of about 1% to about 8% by weight.

8. The makeup removing composition according to claim 1, wherein the total amount of emollient esters does not exceed a total of about 10% by weight of the makeup removing composition.

9. The makeup removing composition according to claim 1, wherein, based on the weight of the makeup removing composition, the at least one polymeric thickener for aqueous systems is present in an amount of about 0.01% to about 1.0% by weight.

10. The makeup removing composition according to claim 1, wherein the at least one polymeric thickener for aqueous systems comprises hydroxyethyl cellulose, and wherein the at least one polyglycerol nonionic surfactant comprises polyglycerol-6 caprylate and polyglycerol dicaprate.

11. The makeup removing composition according to claim 1, wherein, based on the weight of the composition, the at least one polyglycerol nonionic surfactant is present in a total amount of about 0.01% to about 0.2% by weight.

12. The makeup removing composition according to claim 1, wherein, based on the weight of the composition, the at least one polyglycerol nonionic surfactant comprises polyglycerol-6 caprylate present in an amount of about 0.025% by weight and polyglycerol dicaprate present in an amount of about 0.025% by weight.

13. The makeup removing composition according to claim 1, wherein the makeup removing composition comprises one or a combination of additives selected from the following: triethyl citrate, sodium hydroxide, panthenol, hydroxyacetophenone, gluconolactone, myristyl trimethyl ammonium bromide, sodium citrate, sodium chloride, dicaprylyl ether, citric acid, or a combination thereof.

14. The makeup removing composition according to claim 1, wherein a. the oil blend comprises: i. the one or more branched or straight-chain liquid alkanes having a carbon chain length of C11 to C20, which comprises isododecane present at about 28% by weight and isoisohexadecane present at about 15% by weight, and ii. the one or more emollient esters, which comprises isopropyl myristate present at about 1% by weight; b. the at least one polymeric thickener for the aqueous system comprises hydroxyethyl cellulose present at about 0.025% by weight; c. the at least one polyglycerol nonionic surfactant comprises polyglycerol-6 caprylate present at about 0.025% by weight and polyglycerol didecanoate present at about 0.025% by weight; d. water is present at about 45% to about 55% by weight; the composition comprises: e. triethyl citrate; and f. one or a combination of additives selected from the following: sodium hydroxide, panthenol, hydroxyacetophenone, gluconolactone, myristyl trimethyl ammonium bromide, sodium citrate, sodium chloride, dicaprylyl ether, citric acid, or a combination thereof, all amounts being by weight based on the weight of the makeup removing composition, wherein the composition is a micellar two-phase system, wherein water and oil are present in a water-to-oil ratio of about 1:1, and wherein the makeup removing composition can be applied and removed by wiping without rinsing with water.

15. The makeup removing composition according to claim 14, which comprises: a container containing the makeup removing composition; an outlet connected to the container, such as the outlet of a spray nozzle; and a spraying device, wherein the spraying device can release the makeup removing composition in the container via the outlet, wherein the spray nozzle is a fine mist nozzle, and the pump volume of the fine mist nozzle for delivering the mist is about 0.01 to about 1.0 ml / pump and generates micron-sized atomized particles in the range of about 10 to about 900 microns.

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