Patch production system

Abstract

The invention discloses a patch production system which comprises a rack, and a release film unwinding device, a coating device, a non-woven fabric unwinding device, a laminating film-combining device, a cooling device, a traction device, a winding and unwinding device and a release film deviation rectifying device which are arranged on the rack, the laminating and film-fitting device is arranged between the coating device and the traction device, and the cooling device is arranged below the laminating and film-fitting device; and the release film deviation rectifying device is arranged below the coating device. The patch production system has the advantages of reasonable layout, small occupied space, good coating effect, high production quality and the like.

Description

Technical Field

[0001] The present invention relates to the technical field of food and drug packaging machinery and equipment, and specifically relates to a patch production system. Background Art

[0002] With the rapid development of technology, people's living standards have steadily improved, and people's health has become the primary issue in today's society. The intake methods of injection and oral medications may not meet the needs of many patients. Therefore, with the advancement of research, a third method of drug intake has gradually emerged - transdermal patch administration. This method involves evenly coating the drug on a roll of material and then packaging it through corresponding technological processes. When a patient needs to use it, they only need to apply it to the skin surface of the body. The drug comes into close contact with the skin and is absorbed by the skin and then ingested by the patient to treat various diseases. The hot melt adhesive patch, as a new type of transdermal preparation, has better drug release properties, fewer side effects, and is more convenient to use compared to traditional rubber patches.

[0003] To meet the market demand for hot melt adhesive patch drugs, pharmaceutical companies generally have steps such as stirring, coating, cutting, stacking, and four-side sealed inner packaging in the front-end process of producing hot melt patches. For example, a hot melt adhesive patch production line with the application number 202410739855.X includes a coater, a die cutter, a patch weighing machine, a stacker, and a four-side sealed packaging machine. The coater is located upstream of the die cutter, and the die cutter, patch weighing machine, stacker, and four-side sealed packaging machine are connected in sequence. Its unwind roller, coater, laminating roller, cooling roller, and windup roller are arranged in sequence along the length direction of the frame, occupying a large overall space and having an unreasonable layout. Another example is a coater with the application number 202420943198.6, which includes a drying area. At one end of the drying area, there are a release film unwind component, a coating die head, a coating roller, and a material conveying component. The coating die head is located on the side of the coating roller, and the material conveying component is connected to the coating die head. At the other end of the drying area, there are a slitting device and a windup component. The drying area includes at least one hot air drying sub-area and at least one cold air drying sub-area. Its release film unwind component and windup component are both located between the coating roller and the film combining device, resulting in a relatively long overall layout, large space occupation, and unreasonable layout.

[0004] Moreover, the film combining device of the existing coater generally bypasses the release film and the non-woven fabric around the film combining roller and hot-presses and combines the films through a hot pressing mechanism on one side of the film combining roller. This method is prone to wrinkles during the lamination process of the non-woven fabric and the release film, resulting in unqualified product quality. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to overcome the deficiencies of the prior art and provide a patch production system with a reasonable layout, small space occupation, good coating effect, and high production quality.

[0006] To solve the above technical problems, the present invention adopts the following technical solutions:

[0007] A patch production system includes a frame, a release film unwinding device, a coating device, a non-woven fabric unwinding device, a laminating film device, a cooling device, a traction device, a winding and unwinding device, and a release film deviation rectifying device arranged on the frame; the laminating film device is arranged between the coating device and the traction device, the cooling device is arranged below the laminating film device; the release film deviation rectifying device is arranged below the coating device.

[0008] As a further improvement of the above technical solution:

[0009] A flattening device for flattening the non-woven fabric is arranged between the laminating film device and the non-woven fabric unwinding device.

[0010] The flattening device includes an arc roller and a traction roller assembly arranged on the frame in sequence, the traction roller assembly is used for pulling the non-woven fabric in the front side direction of the laminating film device towards the laminating film device, and the arc roller is used for flattening the non-woven fabric.

[0011] A first tension sensor is arranged between the flattening device and the laminating film device.

[0012] The laminating film device includes a pair of laminating rollers, a heating mechanism is arranged in each laminating roller, and each laminating roller is respectively connected with an independent driving mechanism.

[0013] The cooling device includes a cooling roller rotatably arranged on the frame and a rotary driving mechanism for driving the cooling roller to rotate, and a spiral cooling channel extending spirally around the central axis is arranged in the cooling roller.

[0014] A turning device, a half-cutting device and a full-cutting device are further arranged on the frame, the full-cutting device is arranged on the side of the traction device far away from the coating device, the turning device is arranged on the side of the cooling device far away from the laminating film device, the winding and unwinding device is located below the non-woven fabric unwinding device and on the side of the release film unwinding device facing the full-cutting device, and the half-cutting device is arranged between the cooling device and the traction device.

[0015] The turning device is located between the release film unwinding device and the winding and unwinding device.

[0016] Both the half-cutting device and the full-cutting device are located between the non-woven fabric unwinding device and the winding and unwinding device.

[0017] A tensioning device is arranged on the frame between the release film unwinding device and the coating device, a film laminating deviation rectifying device and a second tension sensor are arranged on the frame between the turning device and the half-cutting device, a transfer mechanism, a product conveying mechanism and a film laminating traction mechanism are arranged downstream of the full-cutting device, and the transfer mechanism is used for transferring the product to the product conveying mechanism.

[0018] Compared with the prior art, the advantages of the present invention are:

[0019] The patch production system of the present invention, each device is neither arranged in sequence along the length direction of the frame, and the release film deviation correction device and the unwinding and reeling device are not located between the coating device and the lamination film device, and the layout is reasonable, and the space occupied is small. In addition, the release film deviation correction device is arranged below the coating device, which is conducive to ensuring that the release film from the release film unwinding device to the release film of the coating device has no deflection, and improves the coating effect of the release film. Moreover, a cooling device is arranged below the lamination film device, so as to achieve the effect of timely cooling of the medicine film and improve production quality.

[0020] The patch production system of the present invention can realize the coating and cutting two processes of patch simultaneously. When coating, release film and non-woven fabric are unwound respectively, and after release film arrives at coating device, the stirred medicine is coated on release film, and then non-woven fabric and the release film coated with medicine are laminated in lamination film device, and medicine is transferred to non-woven fabric, and after cooling, deviation correction, tension control, rewinding is carried out, and medicine film can be left to stand at rewinding and unwinding station, and after medicine ripening, cutting (partial medicine that does not need ripening can not be rolled up, directly cut) is carried out. When cutting, the medicine film composed of release film and non-woven fabric passes through half-cut device, traction device and full-cut device successively. Half-cut device only cuts release film, forms easy-tear mouth, and is convenient for the use of product (such as medicine patch). Full-cut device cuts release film into pieces of products (such as medicine patch) of specified size, and redundant waste edge can be pulled to waste edge collection box by traction device. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the coating structure of the patch production system of the present invention.

[0022] Figure 2 It is a schematic diagram of the cutting structure of the patch production system of the present invention.

[0023] Figure 3 It is a structural schematic diagram of the flattening device of the patch production system of the present invention.

[0024] Figure 4 It is a schematic structural diagram of a cooling device of a patch production system of the present invention.

[0025] The symbols in the figure represent:

[0026] 1. Frame; 2. Release film unwinding device; 3. Coating device; 4. Non-woven fabric unwinding device; 5. Laminating film device; 51. Laminating roller; 6. Cooling device; 61. Cooling roller; 62. Rotary drive mechanism; 63. Spiral cooling channel; 7. Steering device; 8. Semi-cutting device; 9. Traction device; 10. Full-cutting device; 11. Rewinding and unwinding device; 12. Flattening device; 121. Arc roller; 122. Traction roller assembly; 123. First tension sensor; 13. Tensioning device; 14. Release film deviation rectifying device; 15. Film laminating deviation rectifying device; 16. Second tension sensor; 17. Transfer mechanism; 18. Product conveying mechanism; 19. Film laminating traction mechanism. Detailed implementation mode

[0027] The present invention will be further described in detail below in conjunction with the accompanying drawings of the specification and specific embodiments.

[0028] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention.

[0029] In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present invention, "a plurality" means two or more, unless otherwise specifically defined.

[0030] In the present invention, unless otherwise clearly defined and limited, the terms "assembled", "connected", "connected", "fixed", etc. should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or integrated; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the internal communication of two elements or the interaction relationship between two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0031] Figures 1 to 4An embodiment of the patch production system of the present invention is shown. The patch production system of this embodiment includes a frame 1, a release film unwinding device 2, a coating device 3, a non-woven fabric unwinding device 4, a laminating film device 5, a cooling device 6, a traction device 9, a winding and unwinding device 11, and a release film deviation rectifying device 14 provided on the frame 1; the laminating film device 5 is arranged between the coating device 3 and the traction device 9, and the cooling device 6 is arranged below the laminating film device 5; the release film deviation rectifying device 14 is arranged below the coating device 3.

[0032] The patch production system of this embodiment is used in the coating process, such as Figure 1 shown:

[0033] Under the unwinding action of the release film unwinding device 2 and the winding action of the winding and unwinding device 11, a release film line is formed for the release film; the release film sequentially passes through the release film deviation rectifying device 14, the coating device 3, the laminating film device 5, the cooling device 6, and the traction device 9. The release film deviation rectifying device 14 rectifies the release film, which is beneficial to ensuring that the release film has no yaw from the release film unwinding device 2 to the coating device 3. The coating device 3 coats the drug on the release film.

[0034] Under the unwinding action of the non-woven fabric unwinding device 4 and the winding action of the winding and unwinding device 11, a non-woven fabric line is formed for the non-woven fabric; the non-woven fabric sequentially passes through the laminating film device 5, the cooling device 6, and the traction device 9. When the non-woven fabric passes through the laminating film device 5, it is laminated to the release film by the laminating film device 5. The laminated drug film (release film and non-woven fabric) jointly passes through the cooling device 6 under the traction action of the traction device 9 and the winding action of the winding and unwinding device 11. The cooling device 6 cools the laminated drug film to cool the drug film to room temperature.

[0035] In this patch production system, the devices are not arranged in sequence along the length direction of the frame 1, and the release film deviation rectifying device 14 and the winding and unwinding device 11 are not located between the coating device 3 and the laminating film device 5. The layout is reasonable and the occupied space is small. Moreover, setting the release film deviation rectifying device 14 below the coating device 3 is beneficial to ensuring that the release film has no yaw from the release film unwinding device 2 to the coating device 3 and improving the coating effect of the release film. Furthermore, setting the cooling device 6 below the laminating film device 5 can achieve the function of timely cooling the drug film and improve the production quality.

[0036] Furthermore, in this embodiment, a flattening device 12 for flattening the non-woven fabric is provided between the laminating film device 5 and the non-woven fabric unwinding device 4. After the non-woven fabric is flattened by the flattening device 12, it enters the laminating film device 5, preventing the non-woven fabric from wrinkling and improving the film laminating effect of the laminating film device 5 on the release film and the non-woven fabric.

[0037] Furthermore, as Figure 3As shown in the figure, in this embodiment, the flattening device 12 includes an arc-shaped roller 121 and a traction roller assembly 122 that are sequentially arranged on the front and rear of the frame 1. The traction roller assembly 122 is used to pull the non-woven fabric in the front lateral direction of the laminating film device 5 towards the laminating film device 5, and the arc-shaped roller 121 is used to flatten the non-woven fabric. The traction roller assembly 122 is used to cut off the tension of the non-woven fabric so that the non-woven fabric is in a tension-free state when entering the laminating film device 5. At the same time, the arc-shaped roller 121 can flatten the non-woven fabric to prevent wrinkles.

[0038] Further, in this embodiment, a first tension sensor 123 is provided between the flattening device 12 and the laminating film device 5. The first tension sensor 123 is used to detect the tension of the non-woven fabric between the flattening device 12 and the laminating film device 5.

[0039] Further, in this embodiment, the laminating film device 5 includes a pair of laminating rollers 51. A heating mechanism is provided in each laminating roller 51, and each laminating roller 51 is respectively connected to an independent driving mechanism. After the coating is completed, the release film and the non-woven fabric jointly pass between a pair of laminating rollers 51, and laminating is performed between the pair of laminating rollers 51. Each laminating roller 51 is respectively connected to an independent driving mechanism, which is beneficial to ensuring that there are no wrinkles, bubbles and other problems in the laminated product.

[0040] Further, as Figure 4 shown, in this embodiment, the cooling device 6 includes a cooling roller 61 rotatably arranged on the frame 1 and a rotary driving mechanism 62 for driving the cooling roller 61 to rotate. A spiral cooling channel 63 extending helically around the central axis is provided in the cooling roller 61. The design of the spiral cooling channel 63 in the cooling roller 61, through simulation analysis and in cooperation with the use of a cooling medium, can quickly and evenly reduce the product to room temperature. Preferably, the cooling medium flows into the cooling channel 63 from one side of the cooling roller 61, and after flowing through the cooling channel 63, it returns to the inflow side through a return pipe, so that the pipeline for transporting the cooling medium can form a closed loop on one side of the cooling roller 61 without having to be routed back through other means.

[0041] Further, in this embodiment, a steering device 7, a semi-cutting device 8 and a full-cutting device 10 are also provided on the frame 1. The full-cutting device 10 is arranged on the side of the traction device 9 away from the coating device 3, the steering device 7 is arranged on the side of the cooling device 6 away from the laminating film device 5, the winding and unwinding device 11 is located below the non-woven fabric unwinding device 4 and on the side of the release film unwinding device 2 facing the full-cutting device 10, and the semi-cutting device 8 is arranged between the cooling device 6 and the traction device 9. Preferably, the release film unwinding device 2 is arranged below the laminating film device 5, and the cooling device 6 is arranged between the release film unwinding device 2 and the laminating film device 5. The steering device 7 is located between the release film unwinding device 2 and the winding and unwinding device 11.

[0042] The patch production system of this embodiment is used in the cutting process, as Figure 2 shown below:

[0043] Under the unwinding action of the release film unwinding device 2 and the winding action of the winding and unwinding device 11, a release film line is formed. The release film sequentially passes through the release film deviation rectifying device 14, the coating device 3, the turning device 7, the semi-cutting device 8, the traction device 9, and the full-cutting device 10. The release film deviation rectifying device 14 rectifies the release film, which is beneficial to ensuring that the release film has no deflection from the release film unwinding device 2 to the coating device 3. The coating device 3 coats the release film with medicine. The turning device 7 turns and supports the release film. The semi-cutting device 8 only cuts the release film to form an easy-to-tear opening, which is convenient for the use of the product. The full-cutting device 10 cuts the release film into products of a specified size, and the excess waste edges can be pulled by the traction device 9 to the waste edge collection box.

[0044] This patch production system can simultaneously implement two processes of coating and cutting of the patch. When coating, the release film and the non-woven fabric are unwound separately. After the release film reaches the coating device 3, the well-stirred medicine is coated on the release film. Then, the non-woven fabric and the release film coated with medicine are laminated in the laminating film device 5, and the medicine is transferred to the non-woven fabric. After cooling, deviation rectification, and tension control, winding is carried out. The medicine film can be statically placed at the winding and unwinding station. After the medicine is matured, cutting is carried out (for some medicines that do not require maturation, winding can be omitted and cutting can be directly carried out). When cutting, the medicine film composed of the release film and the non-woven fabric sequentially passes through the semi-cutting device 8, the traction device 9, and the full-cutting device 10. The semi-cutting device 8 only cuts the release film to form an easy-to-tear opening, which is convenient for the use of the product (such as a medical patch). The full-cutting device 10 cuts the release film into products of a specified size (such as a medical patch), and the excess waste edges can be pulled by the traction device 9 to the waste edge collection box.

[0045] Furthermore, in this embodiment, the turning device 7 is located between the release film unwinding device 2 and the winding and unwinding device 11. The semi-cutting device 8 and the full-cutting device 10 are both located between the non-woven fabric unwinding device 4 and the winding and unwinding device 11. The layout is reasonable and compact.

[0046] Further, in this embodiment, a tension device 13 is provided between the release film unwinding device 2 and the coating device 3 on the frame 1. A film combining deviation rectifying device 15 and a second tension sensor 16 are provided between the turning device 7 and the semi-cutting device 8 on the frame 1. A transfer mechanism 17, a product conveying mechanism 18 and a film combining traction mechanism 19 are provided downstream of the full-cutting device 10 on the frame 1. The transfer mechanism 17 is used to transfer the product to the product conveying mechanism 18. The tension device 13 is used to tension the release film, further improving the coating effect of the coating device 3. The medicine film formed by laminating and combining by the laminating and film combining device 5 sequentially passes through the turning device 7, the film combining deviation rectifying device 15, the second tension sensor 16, the semi-cutting device 8, the traction device 9, the full-cutting device 10 to the winding and unwinding device 11. The film combining deviation rectifying device 15 is used to rectify the deviation of the combined medicine film, which is beneficial to improving the subsequent cutting effect. The second tension sensor 16 can be used to detect the tension of the medicine film. The transfer mechanism 17 can be used to transfer the products produced by cutting to the product conveying mechanism 18, and the product conveying mechanism 18 is used to output the products. Preferably, the tension device 13 is located on the side of the release film unwinding device 2 away from the winding and unwinding device 11. The coating device 3 is located above the tension device 13.

[0047] Although the present invention has been disclosed above with preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make many possible changes and modifications to the technical solution of the present invention, or modify it into an equivalent embodiment with equivalent changes, without departing from the scope of the technical solution of the present invention. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention without departing from the content of the technical solution of the present invention shall fall within the scope of protection of the technical solution of the present invention.

Claims

1. A patch production system, characterized in that: It includes a frame (1), a release film unwinding device (2), a coating device (3), a non-woven fabric unwinding device (4), a laminating film device (5), a cooling device (6), a traction device (9), a winding and unwinding device (11) and a release film deviation rectifying device (14) provided on the frame (1); the laminating film device (5) is arranged between the coating device (3) and the traction device (9), and the cooling device (6) is arranged below the laminating film device (5); the release film deviation rectifying device (14) is arranged below the coating device (3).

2. The patch production system according to claim 1, characterized in that: A flattening device (12) for flattening the non-woven fabric is provided between the laminating film device (5) and the non-woven fabric unwinding device (4).

3. The patch production system according to claim 2, characterized in that: The flattening device (12) includes an arc roller (121) and a traction roller assembly (122) sequentially arranged on the frame (1) from front to back. The traction roller assembly (122) is used to pull the non-woven fabric in the front side direction of the laminating film device (5) towards the laminating film device (5), and the arc roller (121) is used to flatten the non-woven fabric.

4. The patch production system according to claim 2, characterized in that: A first tension sensor (123) is provided between the flattening device (12) and the laminating film device (5).

5. The patch production system according to claim 1, characterized in that: The laminating film device (5) includes a pair of laminating rollers (51). A heating mechanism is provided in each of the laminating rollers (51), and each of the laminating rollers (51) is respectively connected with an independent driving mechanism.

6. The patch production system according to claim 1, characterized in that: The cooling device (6) includes a cooling roller (61) rotatably arranged on the frame (1) and a rotary driving mechanism (62) for driving the cooling roller (61) to rotate. A spiral cooling channel (63) extending spirally around the central axis is provided in the cooling roller (61).

7. The patch production system according to any one of claims 1 to 6, characterized in that: A turning device (7), a semi-cutting device (8) and a full-cutting device (10) are further provided on the frame (1). The full-cutting device (10) is arranged on one side of the traction device (9) away from the coating device (3), the turning device (7) is arranged on one side of the cooling device (6) away from the laminating film device (5), the winding and unwinding device (11) is located below the non-woven fabric unwinding device (4) and on one side of the release film unwinding device (2) facing the full-cutting device (10), and the semi-cutting device (8) is arranged between the cooling device (6) and the traction device (9).

8. The patch production system according to claim 7, wherein: The turning device (7) is located between the release film unwinding device (2) and the winding and unwinding device (11).

9. The patch production system according to claim 7, wherein: Both the semi-cutting device (8) and the full-cutting device (10) are located between the non-woven fabric unwinding device (4) and the winding and unwinding device (11).

10. The patch production system according to claim 7, characterized in that: A tensioning device (13) is provided on the frame (1) between the release film unwinding device (2) and the coating device (3). A film laminating deviation rectifying device (15) and a second tension sensor (16) are provided on the frame (1) between the turning device (7) and the semi-cutting device (8). A transfer mechanism (17), a product conveying mechanism (18) and a film laminating traction mechanism (19) are provided downstream of the full-cutting device (10) on the frame (1). The transfer mechanism (17) is used to transfer the product to the product conveying mechanism (18).

Images