Preparation method of Miao medicine aromatic beads

Abstract

The preparation method comprises the following steps: pretreating traditional Chinese medicinal materials, drying the traditional Chinese medicinal materials, crushing the traditional Chinese medicinal materials, extracting effective components of a Miao medicine prescription, preparing the aromatic beads, processing a finished product and storing. The traditional Chinese medicine residue base material preparation technology is adopted, efficient recycling of waste resources is achieved, the low-temperature sectional drying and superfine grinding technology is adopted, the adsorbability and forming stability of the traditional Chinese medicine residue powder are improved, and the particle size is smaller than or equal to 100 micrometers. By adopting a Miao medicine directional extraction technology and combining an ultrasonic-assisted extraction method, functional components for soothing nerves, repelling mosquitoes and the like in the Miao medicine are accurately extracted, the extraction efficiency is improved by 30%, the active components of the Miao medicine are combined with a traditional incense preparation process, and new age vitality is given to non-abandoned techniques. The plant bonding formula is adopted, the nanmu incense powder and xanthan gum compound adhesive is innovatively used, zero chemical addition of the incense is achieved, no harmful substance is generated during combustion, and solid waste pollution of the traditional Chinese medicine industry is reduced.

Description

Technical Field

[0001] The present invention belongs to the field of preparation of fragrant beads, and particularly relates to a method for preparing fragrant beads of Miao medicine. Background Art

[0002] Traditional Chinese medicine is a treasure of the Chinese nation. As an important part of traditional Chinese medicine, Miao medicine has unique medicinal value and ethnic cultural connotations. At present, the research on Miao medicine mainly focuses on the analysis of medicinal components and clinical applications, but there is still much room for cultural inheritance and productization. Similarly, as an important part of China's intangible cultural heritage, the traditional incense-making technique is at risk of being replaced by modern industrial incense products, and there is also a danger of the traditional incense-making technique being lost. In the current utilization of traditional Chinese medicine residues, most of them focus on composting or fuelization, and there is a lack of development in high-value-added products. Summary of the Invention

[0003] Object of the Invention: To solve the deficiencies of the prior art, the present invention provides a method for preparing fragrant beads of Miao medicine, which combines Miao medicine culture with the ancient non-heritage incense-making method to create an innovative product with oriental aesthetics and cultural connotations; develops a technology for reusing traditional Chinese medicine residues, endows waste resources with new value, and promotes environmental protection and resource recycling; takes fragrant beads as a carrier, integrates the triple values of health, culture, and environmental protection, and meets the pursuit of modern consumers for a high-quality life.

[0004] Technical Solution: A method for preparing fragrant beads of Miao medicine, comprising the following steps:

[0005] Step 1. Pretreat traditional Chinese medicine materials:

[0006] a. Cleaning: Rinse the recycled and used traditional Chinese medicine materials with clean water to remove sediment and impurities;

[0007] b. Drainage: Drain the water from the cleaned traditional Chinese medicine materials, and then dehydrate them with a centrifuge to avoid mildew caused by excessive water during the subsequent drying process;

[0008] Step 2. Dry traditional Chinese medicine materials: Adopt a low-temperature segmented drying process. During the drying process, maintain the low humidity of the hot air through dehumidification technology to improve the drying efficiency; the specific operation is as follows:

[0009] The first stage: Use hot air at a relatively low temperature to pre-dry the materials to reduce the moisture content of the materials to a certain extent;

[0010] The second stage: Further dry under the combined action of microwave and hot air;

[0011] The third stage: Use hot air to dry again until the materials reach the required final moisture content requirement;

[0012] Step 3. Crushing Chinese medicinal materials: The ultrafine crushing process is adopted, and the specific operation is as follows:

[0013] (1) Preparation work: Prepare the Chinese medicinal materials to be crushed; check whether the equipment is normal, whether each component is fastened, and whether the power cord and power plug are normal; put the Chinese medicinal materials into the hopper, turn on the power switch, and after confirming that the voltage is stable and correct, turn on the power switch;

[0014] (2) Start crushing: According to the types and crushing requirements of the Chinese medicinal materials, adjust the parameters of rotation speed, temperature, and crushing time, press the start button to start working. During the crushing process, observe the working state of the crusher and adjust the parameters to obtain a better crushing effect;

[0015] (3) Crushing completion: When the crushing time reaches the preset time or the ideal crushing degree is achieved, stop working, turn off the power switch, take out the ultrafine powder of the crushed Chinese medicine, and carry out packaging and storage;

[0016] (4) Cleaning and disinfection: After use, it needs to be cleaned and disinfected. First, clean the residues in the crusher, and then disinfect each component of the crusher with a disinfectant to ensure hygienic safety during the next use;

[0017] Step 4. Extracting the active ingredients of the Miao medicine prescription: The ultrasonic-assisted extraction method is adopted for extraction, and the specific operation is as follows:

[0018] A. Preparation work: Configure the Miao medicine materials according to the proportion of the Miao medicine prescription, crush the Miao medicine materials to increase their surface area for better contact with the extraction solvent;

[0019] B. Mixing the medicine powder and the extraction solvent: Select ethanol as the extraction solvent, mix the crushed medicine powder with ethanol at a ratio of 1:10 g / mL, and put it into a distillation flask;

[0020] C. Ultrasonic treatment: Place the container containing the sample and ethanol in an ultrasonic water bath or an ultrasonic extractor, set the corresponding parameters for ultrasonic treatment. The ultrasonic power is in the range of 200 - 1000 W, and an appropriate power can be selected according to the sample amount and equipment capacity; the ultrasonic frequency is between 20 - 40 kHz. Different frequencies have an impact on the extraction effect and need to be adjusted according to the specific situation;

[0021] D. Monitoring the extraction process: During the ultrasonic treatment process, take samples regularly for analysis to monitor the extraction situation of the target components;

[0022] E. Extract Separation: After the ultrasonic treatment, first use filter paper or filter cloth to roughly filter the extract to remove medicinal residues and large particle impurities; then further use a microfiltration membrane for fine filtration to remove fine particles; finally, centrifuge the extract by putting it into a centrifuge to separate solid impurities and the supernatant.

[0023] F. Post-treatment of the Extract: Adopt the method of reduced-pressure concentration to avoid damaging heat-sensitive components in traditional Chinese medicine at high temperatures. Pour the extract into the evaporation flask of a rotary evaporator; set the water bath temperature, turn on the vacuum pump, reduce the system pressure, and evaporate the solvent at a lower temperature. Collect the concentrated solution until the required volume or concentration is reached.

[0024] Step Five: Making Incense Beads:

[0025] 1) Powder Mixing: Use a 1500-mesh sieve to screen the medicinal powder and Phoebe zhennan powder in a ratio of 7:3, and mix them evenly.

[0026] 2) Adding and Mixing the Extract: Add the extracted Miao medicine extract to the mixture. The ratio of the mixture to the extract is 1:1. Stir while adding, and knead the mixture into a uniform dough-like shape, ensuring that there is no dry powder or excessive wetness, and it is appropriate to be able to form a ball without sticking to the hands.

[0027] 3) Shaping: Seal the dough-like mixture with plastic wrap and ferment for 1 hour. Take an appropriate amount of the mixture and roll it into small balls with a diameter of 1 - 1.5 cm, ensuring that the surface of the incense beads is smooth without cracks; Fill the mixture into a mold, press it firmly and then demold to obtain incense beads with regular shapes. If there are cracks on the surface of the incense beads, moisten your finger with a little water and gently smooth them.

[0028] 4) Natural Drying: Place the shaped incense beads on a drying rack and let them dry naturally in a ventilated and cool place. The drying time is 3 - 5 days, depending on the specific environment.

[0029] 5) Sanding, Polishing and Waxing: The surface of the dried incense beads may be slightly rough. Gently sand it with fine sandpaper of 800 - 1000 meshes to make the surface smooth, wipe the incense beads with a polishing board to make the surface shiny, and finally apply wood wax oil to prevent insects and moisture.

[0030] Step Six: Processing Finished Products: Package the made incense beads into bracelets, necklaces, hairpins, hair clips, etc. to improve the aesthetic value and commercial value.

[0031] Step Seven: Storage: Put the incense products into a sealed bag or sealed jar and store them in a cool and dry place.

[0032] As an optimization: In the step of drying traditional Chinese medicine in Step Two, in the first stage, use hot air at a temperature of 40 - 60 °C to pre-dry the material for 15 - 30 minutes.

[0033] As an optimization: in the second step of drying Chinese medicinal materials, in the second stage, further drying is carried out under the combined action of microwaves of 2000 - 3000 MHz and hot air of 40 - 60 °C for a duration of 10 - 15 min.

[0034] As an optimization: in the second step of drying Chinese medicinal materials, in the third stage, hot air of 40 - 55 °C is used again for drying for a duration of 10 - 15 min until the material meets the requirement of a final moisture content ≤ 5%.

[0035] As an optimization: in the third step of crushing Chinese medicinal materials, the preset crushing time is 30 min, and the particle size requirement for crushing reaches 1250 - 2000 mesh.

[0036] As an optimization: in the fourth step of extracting the active ingredients of the Miao medicine prescription, the extraction conditions are as follows: the extraction time is 10 - 60 min; the extraction temperature is usually between room temperature and 80 °C to prevent the loss of thermosensitive components due to temperature, and multiple extractions are carried out to improve the extraction rate.

[0037] As an optimization: in the fourth step of extracting the active ingredients of the Miao medicine prescription, the extraction liquid is separated using a microporous filter membrane with a pore size of 0.22 - 0.45 μm, and the extraction liquid is centrifuged in a centrifuge at 3000 - 5000 rpm for 10 - 15 min.

[0038] As an optimization: in the fourth step of extracting the active ingredients of the Miao medicine prescription, the water bath temperature for the post-treatment of the extraction liquid is 40 °C - 60 °C.

[0039] Beneficial effects: The specific advantages of the present invention are as follows:

[0040] (1) The present invention adopts the technology of preparing Chinese medicine residue base materials, realizes the efficient reuse of waste resources, and adopts the processes of low-temperature segmented drying and ultrafine grinding to improve the adsorption and forming stability of Chinese medicine residue powder, with a particle size ≤ 100 μm.

[0041] (2) The present invention adopts the Miao medicine directional extraction technology, combined with the ultrasonic-assisted extraction method, to accurately extract the efficacy components such as calming the nerves and repelling mosquitoes in the Miao medicine, with the extraction efficiency increased by 30%. Combining the active ingredients of the Miao medicine with the traditional incense-making process endows the intangible cultural heritage skills with new vitality in the new era.

[0042] (3) The present invention adopts a plant binder formula, innovatively uses a compound binder of Phoebe zhennan wood powder and xanthan gum with a ratio of 3:1, realizes zero chemical addition in the incense product and no harmful substances during combustion, reduces the solid waste pollution in the Chinese medicine industry, and meets the compound consumption demands of health, culture, and environmental protection. Specific implementation manners

[0043] The technical solutions in the embodiments of the present invention will be clearly and completely described below, so that those skilled in the art can better understand the advantages and features of the present invention, and thus more clearly define the protection scope of the present invention. The embodiments described in the present invention are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts belong to the protection scope of the present invention.

[0044] Specific Embodiment 1: Exorcising and Soothing Fragrant Beads

[0045] The raw materials are as follows: mugwort (30 grams), semen platycladi (20 grams), acorus tatarinowii (20 grams), angelica dahurica (10 grams), sandalwood powder (10 grams), and natural binder.

[0046] Mugwort is the holy herb for exorcising evil spirits in the "Five Poisonous Months" of the Miao nationality. Acorus tatarinowii is used in Miao medicine to awaken the mind and open the orifices. The combination of the two reflects the concept of "removing filth and strengthening the healthy qi". Among them, the volatile oil of mugwort (cineole, camphor) can inhibit pathogenic bacteria in the air, and the purification rate reaches 85%. Semen platycladi contains cupressol, which regulates GABA receptors through the olfactory nerve and relieves anxiety. The effects of this exorcising and soothing fragrant bead are as follows: relieving stress, refreshing the air, soothing the nerves and helping sleep, and expelling insects.

[0047] The usage scenario of this embodiment is as follows: It is suitable for hanging in the bedroom or making into a sachet to wear, and has a significant effect on people with insomnia and dreaminess.

[0048] Specific Embodiment 2: Mosquito-Repellent and Insect-Repellent Fragrant Beads

[0049] The raw materials are as follows: artemisia annua (25 grams), mint leaves (15 grams), atractylodes lancea (20 grams), camphorwood powder, and beeswax.

[0050] Artemisia annua is a traditional insect-repellent medicine in the mountainous areas of the Miao nationality. Its active ingredient, artemisinin derivatives, can interfere with the olfactory receptors of mosquitoes. Menthol in mint has an effective mosquito-repellent duration of up to 5 hours and is non-irritating to the skin. Camphorwood powder contains natural camphor, and the insect-repellent rate is 98%, which is better than chemical mosquito repellents, as shown in Table 1 below. The effects of this mosquito-repellent and insect-repellent fragrant bead are as follows: repelling insects, cooling and refreshing.

[0051] Table 1: Comparative Test Table of Mosquito-Repellent and Insect-Repellent Fragrant Beads

[0052]

[0053] Note: The mosquito-repellent effect is tested by simulating the mosquito environment in the laboratory.

[0054] The usage scenario of this embodiment is as follows: It can be embedded in outdoor clothing or made into a car perfume tablet, which is environmentally friendly, safe, and suitable for mothers and infants.

[0055] Specific Embodiment 3: Blood-Activating and Heart-Nourishing Fragrant Beads

[0056] The raw materials are as follows: safflower (25g), angelica powder (20g), dried osmanthus (12g), frankincense powder (15g), and appropriate amount of natural clay.

[0057] Safflower has the effect of "activating meridians and dissipating stasis", and angelica has the effect of "tonifying blood and restoring the yuan", which conforms to the principle of "dual regulation of qi and blood" in Miao medicine. Carthamin in safflower can dilate microvessels, and the hand temperature increases by 2 - 3°C after wearing (infrared thermal imaging test). Linalool in osmanthus stimulates the parasympathetic nerve through smell, and the heart rate fluctuation decreases by 15% (measured by users wearing the monitor), as shown in Table 2 below. The effects of this blood-activating and heart-nourishing fragrant bead are as follows: promoting qi and blood circulation, removing blood stasis and promoting blood circulation, and regulating qi and blood.

[0058] Table 2 Comparative test table of blood-activating and heart-nourishing fragrant beads

[0059]

[0060] Note: Heart rate variability is measured by a heart rate monitor, and sleep quality is evaluated through a user questionnaire.

[0061] The usage scenario of this embodiment is as follows: It is suitable for sedentary office workers and women with qi and blood deficiency, and can be worn with wrist acupoints to enhance absorption.

[0062] Specific Example 4: Miao Ling Qing Xiang Zhu

[0063] The raw materials are as follows: houttuynia cordata (25g), mountain spicy tree (20g), dried tangerine peel (15g), pine needle powder (15g), and natural resin glue.

[0064] Houttuynia cordata (heartleaf houttuynia) is a daily food therapy material for the Miao people, and mountain spicy tree is a unique spice in the Miao Mountains, reflecting "the homology of medicine and food". The adsorption rate of volatile oil (decanoyl acetaldehyde) in houttuynia cordata to formaldehyde exceeds 90%, which is suitable for removing formaldehyde in new houses. The citral content in mountain spicy tree reaches 70%, and the refreshing effect is better than caffeine. The effects of this Miao Ling Qing Xiang Zhu are as follows: purifying the air, relieving fatigue, regulating qi and strengthening the spleen.

[0065] The usage scenario of this embodiment is as follows: It can be made into bookmark incense tablets or office ornaments, combining functionality and cultural aesthetics.

[0066] Specific Example 5: Miao Ethnic Mosquito-Repellent Fragrant Beads

[0067] The raw materials are as follows: 10 grams each of mugwort leaf, dahurian angelica root, clove, honeysuckle flower, mint, calamus, perilla leaf, and agastache rugosa, and appropriate amount of natural binder.

[0068] Compound mosquito repellent, using Artemisia argyi and Syzygium aromaticum in synergy to interfere with the CO2 perception ability of mosquitoes (the repellent rate is increased by 40%). Chlorogenic acid in honeysuckle can soothe the skin and avoid the allergy risk of chemical mosquito repellents. The effects of this Miao mosquito repellent incense beads are as follows: mosquito repellent, calming the nerves, helping sleep, clearing heat and detoxifying. The patterns of the sachet adopt the Miao totem "Mother Butterfly", combining intangible cultural heritage techniques and practical functions.

[0069] Specific Example 6 Adult mosquito repellent incense beads

[0070] The raw materials are as follows: 8 grams each of honeysuckle, Artemisia argyi, Perilla frutescens, Syzygium aromaticum, Pogostemon cablin, Mentha haplocalyx, and Citrus reticulata Blanco, and an appropriate amount of natural binder.

[0071] Technical upgrade:

[0072] Perillaldehyde and eugenol form a sustained-release microcapsule structure, and the mosquito repellent time is extended to 8 hours. Hesperidin in Citrus reticulata Blanco can neutralize the sour smell of sweat and is suitable for outdoor use by sports people. The effects of this adult mosquito repellent incense beads are as follows: mosquito repellent, calming the nerves, helping sleep, clearing heat and detoxifying, featuring "natural + long-lasting". Specific Example 7

[0074] A preparation method of Miao medicine incense beads includes the following steps:

[0075] Step 1. Pretreat the Chinese medicinal materials:

[0076] a. Cleaning: Rinse the recycled used Chinese medicinal materials with clean water to remove sediment and impurities;

[0077] b. Draining: Drain the water from the cleaned Chinese medicinal materials, and then dehydrate them with a centrifuge to avoid mildew caused by excessive moisture during the subsequent drying process;

[0078] Step 2. Dry the Chinese medicinal materials: Adopt a low-temperature segmented drying process. During the drying process, maintain the low humidity of the hot air through dehumidification technology to improve the drying efficiency; the specific operation is as follows:

[0079] The first stage: Use hot air at a temperature of 40°C to pre-dry the material for 15 minutes to reduce the moisture content of the material to a certain extent;

[0080] The second stage: Further dry under the combined action of microwave at 2000 MHz and hot air at 40°C for 10 minutes;

[0081] The third stage: Use hot air at 40°C to dry again for 10 minutes until the material reaches the final moisture content requirement ≤5%;

[0082] Step 3. Crush the Chinese medicinal materials: Adopt an ultrafine crushing process, and the specific operation is as follows:

[0083] (1) Preparation: Prepare the traditional Chinese medicine materials to be pulverized; check whether the equipment is normal, whether each component is fastened, and whether the power cord and power plug are normal; put the traditional Chinese medicine materials into the hopper, turn on the power switch, and after confirming that the voltage is stable and correct, turn on the power switch;

[0084] (2) Start pulverizing: According to the types and pulverizing requirements of the traditional Chinese medicine materials, adjust parameters such as rotation speed, temperature, and pulverizing time, press the start button to start working. During the pulverizing process, observe the working state of the pulverizer and adjust the parameters to obtain a better pulverizing effect;

[0085] (3) Pulverizing completed: When the pulverizing time reaches the preset time of 30 min or reaches the ideal pulverizing degree and the pulverizing particle size reaches 1250 mesh, stop working and turn off the power switch. Take out the pulverized traditional Chinese medicine ultrafine powder and carry out packaging and storage;

[0086] (4) Cleaning and disinfection: After use, it needs to be cleaned and disinfected. First, clean the residues in the pulverizer, and then disinfect each component of the pulverizer with a disinfectant to ensure hygienic safety for the next use;

[0087] Step 4. Extract the active ingredients of the Miao medicine prescription: Use ultrasonic-assisted extraction method for extraction. The specific operations are as follows:

[0088] A. Preparation: Configure the Miao medicine materials according to the proportion of the Miao medicine prescription, pulverize the Miao medicine materials to increase their surface area for better contact with the extraction solvent;

[0089] B. Mix the medicine powder and the extraction solvent: Select ethanol as the extraction solvent, mix the pulverized medicine powder and ethanol at a ratio of 1:10 g / mL, and put them into a distillation flask;

[0090] C. Ultrasonic treatment: Place the container containing the sample and ethanol in an ultrasonic water bath or an ultrasonic extractor, set the corresponding parameters for ultrasonic treatment. Ultrasonic power: within the range of 200 - 1000 W, a suitable power can be selected according to the sample amount and equipment capacity. Ultrasonic frequency: between 20 - 40 kHz, different frequencies have an impact on the extraction effect and need to be adjusted according to specific circumstances;

[0091] D. Monitoring of the extraction process: During the ultrasonic treatment process, regularly take samples for analysis to monitor the extraction of the target components: Extraction time: 10 min; Extraction temperature: usually between room temperature and 80 °C to prevent the loss of thermosensitive components due to temperature, and perform multiple extractions to improve the extraction rate;

[0092] E. Extract separation: After the ultrasonic treatment, first use filter paper or filter cloth to roughly filter the extract to remove medicinal residues and large particle impurities; then further use a 0.22 μm microporous filter membrane for fine filtration to remove fine particles; finally, centrifuge. Put the extract into a centrifuge and centrifuge at 3000 rpm for 10 min to separate solid impurities and supernatant;

[0093] F. Post-treatment of the extract: Adopt the vacuum concentration method to avoid destroying the thermosensitive components in traditional Chinese medicine at high temperature. Pour the extract into the evaporation flask of a rotary evaporator; set the water bath temperature to 40 °C, turn on the vacuum pump, reduce the system pressure, and evaporate the solvent at a lower temperature. Collect the concentrated solution until the required volume or concentration is reached;

[0094] Step Five: Making incense beads:

[0095] 1) Medicinal powder mixing: Sieve the medicinal powder and Phoebe nanmu adhesive powder in a ratio of 7:3 with a 1500-mesh sieve and mix evenly;

[0096] 2) Adding and mixing the extract: Add the extracted Miao medicine extract to the mixture. The ratio of the mixture to the extract is 1:1. Stir while adding and knead the mixture into a uniform dough shape, ensuring that there is no dry powder or excessive moisture, and it is appropriate to be able to knead into a ball without sticking to the hands;

[0097] 3) Shaping: Seal the dough-like mixture with plastic wrap and ferment for 1 hour. Take an appropriate amount of the mixture and roll it into small balls with a diameter of about 1 cm, ensuring that the surface of the incense beads is smooth and crack-free; Fill the mixture into a mold, compact it and then demold to obtain incense beads with regular shapes. If there are cracks on the surface of the incense beads, moisten your finger with a little water and gently smooth them;

[0098] 4) Natural drying: Place the shaped incense beads on a drying rack and let them dry naturally in a ventilated and cool place. The drying time is 3 days, depending on the specific environment;

[0099] 5) Sanding, polishing and waxing: The surface of the dried incense beads may be slightly rough. Gently sand it with 800-mesh fine sandpaper to make the surface smooth, wipe the incense beads with a polishing board to make the surface shiny, and finally apply wood wax oil to prevent insects and moisture;

[0100] Step Six: Processing the finished product: Package the made incense beads into incense bead bracelets, necklaces, hairpins, hair clips, etc. to improve the aesthetic value and commercial value;

[0101] Step Seven: Storage: Put the incense products into a sealed bag or sealed jar and store them in a cool and dry place. Specific Example 8

[0103] A preparation method of Miao medicine incense beads includes the following steps:

[0104] Step One: Pretreating traditional Chinese medicine materials:

[0105] a. Cleaning: Rinse the recycled and used Chinese medicinal materials with clean water to remove sediment and impurities.

[0106] b. Drainage: Drain the water from the cleaned Chinese medicinal materials, and then dehydrate them with a centrifuge to avoid mildew caused by excessive moisture during the subsequent drying process.

[0107] Step Two: Dry the Chinese medicinal materials: Adopt a low-temperature segmented drying process. During the drying process, maintain the low humidity of the hot air through dehumidification technology to improve the drying efficiency. The specific operations are as follows:

[0108] The first stage: Pre-dry the materials with hot air at a temperature of 60°C for 30 minutes to reduce the moisture content of the materials to a certain extent.

[0109] The second stage: Further dry under the combined action of microwave at 3000 MHz and hot air at 60°C for 15 minutes.

[0110] The third stage: Dry again with hot air at 55°C for 15 minutes until the materials reach the final moisture content requirement ≤ 5%.

[0111] Step Three: Crush the Chinese medicinal materials: Adopt an ultrafine crushing process. The specific operations are as follows:

[0112] (1) Preparation work: Prepare the Chinese medicinal materials to be crushed; check whether the equipment is normal, whether each component is fastened, and whether the power cord and power plug are normal; put the Chinese medicinal materials into the hopper, turn on the power switch, and after confirming that the voltage is stable and correct, turn on the power switch.

[0113] (2) Start crushing: According to the type and crushing requirements of the Chinese medicinal materials, adjust parameters such as rotation speed, temperature, and crushing time, press the start button to start working. During the crushing process, observe the working state of the crusher and adjust the parameters to obtain a better crushing effect.

[0114] (3) Crushing completion: When the crushing time reaches the preset time of 30 minutes or reaches the ideal crushing degree and the crushing particle size reaches 2000 mesh, stop working and turn off the power switch. Take out the crushed ultrafine powder of Chinese medicine and package it for storage.

[0115] (4) Cleaning and disinfection: After use, it needs to be cleaned and disinfected. First, clean the residues in the crusher, and then disinfect each component of the crusher with a disinfectant to ensure hygienic safety during the next use.

[0116] Step Four: Extract the effective components of the Miao medicine prescription: Adopt ultrasonic-assisted extraction method for extraction. The specific operations are as follows:

[0117] A. Preparation: Configure the Miao medicine herbs according to the proportion of the Miao medicine formula, and pulverize the Miao medicine herbs to increase their surface area for better contact with the extraction solvent;

[0118] B. Mixing the medicine powder and the extraction solvent: Select ethanol as the extraction solvent, mix the pulverized medicine powder and ethanol at a ratio of 1:10 g / mL, and put them into a distillation flask;

[0119] C. Ultrasonic treatment: Place the container containing the sample and ethanol in an ultrasonic water bath or an ultrasonic extractor, set the corresponding parameters for ultrasonic treatment. Ultrasonic power: within the range of 200 - 1000 W, an appropriate power can be selected according to the sample amount and the equipment capacity. Ultrasonic frequency: between 20 - 40 kHz. Different frequencies have an impact on the extraction effect and need to be adjusted according to specific circumstances;

[0120] D. Monitoring the extraction process: During the ultrasonic treatment process, sample regularly for analysis to monitor the extraction of the target components. Extraction time: 60 min; Extraction temperature: usually between room temperature and 80 °C to prevent the loss of heat-sensitive components due to temperature. Conduct multiple extractions to improve the extraction rate;

[0121] E. Separation of the extract: After the ultrasonic treatment, first use filter paper or filter cloth to coarsely filter the extract to remove the medicinal residues and large particle impurities; then further use a 0.45 μm microporous filter membrane for fine filtration to remove fine particles; finally, centrifuge. Put the extract into a centrifuge and centrifuge at 5000 rpm for 15 min to separate the solid impurities and the supernatant;

[0122] F. Post-treatment of the extract: Adopt the method of vacuum concentration to avoid destroying the heat-sensitive components in traditional Chinese medicine. Pour the extract into the evaporation flask of a rotary evaporator; Set the water bath temperature to 60 °C, turn on the vacuum pump to reduce the system pressure, so that the solvent evaporates at a lower temperature, and collect the concentrated solution until the required volume or concentration is reached;

[0123] Step Five: Making fragrant beads:

[0124] 1) Mixing the medicine powder: Sieve the medicine powder and Phoebe nanmu adhesive powder with a ratio of 7:3 through a 1500-mesh sieve and mix them evenly;

[0125] 2) Adding and mixing the extract: Add the extracted Miao medicine extract to the mixture. The ratio of the mixture to the extract is 1:1. Stir while adding, and knead the mixture into a uniform dough-like shape, ensuring that there is no dry powder or excessive moisture, and it is appropriate to be able to knead into a ball and not stick to the hands;

[0126] 3) Shaping: Seal the dough-like mixture with plastic wrap and ferment it for 1 hour. Take an appropriate amount of the mixture and roll it into small balls with a diameter of about 1.5 cm by hand, ensuring that the surface of the incense beads is smooth and free of cracks. Fill the mixture into the mold, compact it and then demold to obtain incense beads with regular shapes. If there are cracks on the surface of the incense beads, moisten your finger with a small amount of water and gently smooth them out.

[0127] 4) Natural drying: Place the shaped incense beads on a drying rack and let them dry naturally in a well-ventilated and cool place. The drying time is 5 days, depending on the specific environment.

[0128] 5) Sanding, polishing and waxing: The surface of the dried incense beads may be slightly rough. Gently sand them with fine sandpaper of 1000 mesh to make the surface smooth, wipe the incense beads with a polishing board to make the surface shiny, and finally apply wood wax oil to prevent insects and moisture.

[0129] Step Six: Processing the finished product: Package the made incense beads into bracelets, necklaces, hairpins, hair clips, etc. to improve the aesthetic value and commercial value.

[0130] Step Seven: Storage: Put the incense products into a sealed bag or sealed jar and store them in a cool and dry place. Specific Example 9

[0132] A preparation method of Miao medicine incense beads includes the following steps:

[0133] Step One: Pretreating traditional Chinese medicine materials:

[0134] a. Cleaning: Rinse the recycled and used traditional Chinese medicine materials with clean water to remove sand and impurities.

[0135] b. Draining: Drain the water from the cleaned traditional Chinese medicine materials, and then dehydrate them with a centrifuge to avoid mildew caused by excessive moisture during the subsequent drying process.

[0136] Step Two: Drying traditional Chinese medicine materials: Adopt a low-temperature segmented drying process. During the drying process, maintain the low humidity of the hot air through dehumidification technology to improve the drying efficiency. The specific operation is as follows:

[0137] The first stage: Use hot air at a temperature of 50 °C to pre-dry the materials for 24 minutes, so that the moisture content of the materials is reduced to a certain level.

[0138] The second stage: Further dry under the combined action of microwave at 2500 MHz and hot air at 50 °C for 12 minutes.

[0139] The third stage: Use hot air at 48 °C to dry again for 14 minutes until the materials meet the final moisture content requirement ≤ 5%.

[0140] Step 3. Crushing Chinese medicinal materials: The ultrafine crushing process is adopted, and the specific operation is as follows:

[0141] (1) Preparation work: Prepare the Chinese medicinal materials to be crushed; check whether the equipment is normal, whether each component is fastened, and whether the power cord and power plug are normal; put the Chinese medicinal materials into the hopper, turn on the power switch, and after confirming that the voltage is stable and correct, turn on the power switch;

[0142] (2) Start crushing: According to the types and crushing requirements of the Chinese medicinal materials, adjust parameters such as rotation speed, temperature, and crushing time, press the start button to start working. During the crushing process, observe the working state of the crusher and adjust the parameters to obtain a better crushing effect;

[0143] (3) Crushing completion: When the crushing time reaches the preset time of 30 minutes or reaches the ideal crushing degree and the crushing particle size reaches 1800 mesh, stop working and turn off the power switch. Take out the crushed ultrafine powder of Chinese medicine and carry out packaging and storage;

[0144] (4) Cleaning and disinfection: After use, it needs to be cleaned and disinfected. First, clean the residues in the crusher, and then disinfect each component of the crusher with a disinfectant to ensure hygienic safety during the next use;

[0145] Step 4. Extracting the effective components of the Miao medicine prescription: The ultrasonic-assisted extraction method is adopted for extraction, and the specific operation is as follows:

[0146] A. Preparation work: Configure the Miao medicine materials according to the proportion of the Miao medicine prescription, and crush the Miao medicine materials to increase their surface area for better contact with the extraction solvent;

[0147] B. Mixing the medicine powder and the extraction solvent: Select ethanol as the extraction solvent, mix the crushed medicine powder and ethanol at a ratio of 1:10 g / mL, and put them into a distillation flask;

[0148] C. Ultrasonic treatment: Place the container containing the sample and ethanol in an ultrasonic water bath or an ultrasonic extractor, and set the corresponding parameters for ultrasonic treatment. Ultrasonic power: within the range of 200 - 1000 W, a suitable power can be selected according to the sample amount and equipment capacity. Ultrasonic frequency: between 20 - 40 kHz. Different frequencies have an impact on the extraction effect and need to be adjusted according to specific circumstances;

[0149] D. Monitoring the extraction process: During the ultrasonic treatment process, take samples regularly for analysis to monitor the extraction of the target components. Extraction time: 40 minutes; Extraction temperature: usually between room temperature and 80 °C to prevent the loss of heat-sensitive components due to temperature. Conduct multiple extractions to improve the extraction rate;

[0150] E. Extract separation: After the ultrasonic treatment, first use filter paper or filter cloth to roughly filter the extract to remove medicinal residues and large particle impurities; then further use a 0.37 μm microporous membrane for fine filtration to remove fine particles; finally, centrifuge. Put the extract into a centrifuge and centrifuge at 4000 rpm for 13 min to separate solid impurities and supernatant;

[0151] F. Post-treatment of the extract: Adopt the method of reduced pressure concentration to avoid destroying the thermosensitive components in traditional Chinese medicine at high temperature. Pour the extract into the evaporation flask of a rotary evaporator; set the water bath temperature to 50 °C, turn on the vacuum pump to reduce the system pressure, so that the solvent evaporates at a lower temperature, and collect the concentrated solution until the required volume or concentration is reached;

[0152] Step Five: Making incense beads:

[0153] 1) Powder mixing: Use a 1500-mesh sieve to sieve medicinal powder and Phoebe zhennan powder in a ratio of 7:3, and mix them evenly;

[0154] 2) Adding and mixing the extract: Add the extracted Miao medicine extract to the mixture. The ratio of the mixture to the extract is 1:1. Stir while adding, and knead the mixture into a uniform dough-like shape, ensuring that there is no dry powder or excessive moisture, and it is appropriate to be able to knead into a ball without sticking to the hands;

[0155] 3) Shaping: Seal the dough-like mixture with plastic wrap and ferment for 1 hour. Take an appropriate amount of the mixture and roll it into small balls with a diameter of about 1.2 cm, ensuring that the surface of the incense beads is smooth and without cracks; Fill the mixture into a mold, press it firmly and then demold to obtain incense beads with regular shapes. If there are cracks on the surface of the incense beads, moisten your fingers with a little water and gently smooth them;

[0156] 4) Natural drying: Place the shaped incense beads on a drying rack and let them dry naturally in a ventilated and cool place. The drying time is 4 days, depending on the specific environment;

[0157] 5) Sanding, polishing and waxing: The surface of the dried incense beads may be slightly rough. Gently sand it with 900-mesh fine sandpaper to make the surface smooth. Wipe the incense beads with a polishing board to make the surface shiny. Finally, apply wood wax oil to prevent insects and moisture;

[0158] Step Six: Processing the finished product: Package the made incense beads into bracelets, necklaces, hairpins, hair clips, etc. to improve the aesthetics and commercial value;

[0159] Step Seven: Storage: Put the incense products into a sealed bag or sealed jar and store them in a cool and dry place.

[0160] The test of the influence of the ultra-fine grinding particle size on the quality of incense beads in the present invention is as follows:

[0161] Test method: The dried Chinese medicinal materials were respectively pulverized to 1250 mesh, 1800 mesh, and 2000 mesh, and 50 g of powder was taken from each. Through the adsorption test, the powder was placed in a closed container containing volatile organic gases (VOCs) at a certain concentration. After a period of time, the gas concentration in the container was detected, and the adsorption rate of the powder to VOCs was calculated; for the forming stability test, the powder was made into incense bead blanks, and the deformation and cracking conditions during natural drying were observed, and the forming success rate was recorded.

[0162] Test results: The adsorption rate of the 1250-mesh powder to VOCs was 75%, and the forming success rate was 80%; the adsorption rate of the 1800-mesh powder reached 85%, and the forming success rate was 90%; the adsorption rate of the 2000-mesh powder was 90%, and the forming success rate was 92%. Considering comprehensively, the 1800-mesh powder showed a relatively balanced performance in terms of adsorption and forming stability. It could not only effectively adsorb odors but also ensure a high forming quality. The particle size was detected to be ≤100 μm, meeting the expected requirements, as shown in Table 3 below.

[0163] Table 3 Influence of ultra-fine grinding particle size on the quality of incense beads

[0164] Particle size (mesh) Hardness of the incense beads Uniformity of the incense beads Duration of fragrance retention (hours) 1000 3.8 85％ 48 1500 4.2 92％ 60 2000 4.5 95％ 72

[0165] Note: The hardness of the incense beads was measured by a Shore hardness tester, the uniformity was evaluated by visual inspection, and the aroma persistence was evaluated by sensory testing.

[0166] The test on the influence of ultrasonic-assisted extraction on the extraction efficiency in the present invention is as follows:

[0167] Taking the formula of the exorcising and calming the nerves incense beads as an example, different ultrasonic powers (200 W, 600 W, 1000 W), frequencies (20 kHz, 30 kHz, 40 kHz), and extraction times (10 min, 40 min, 60 min) were set respectively, and each group of tests was repeated 3 times. High-performance liquid chromatography (HPLC) was used to determine the contents of the target efficacy components such as calming the nerves and repelling mosquitoes in the extract, and the extraction efficiency was calculated.

[0168] Test results: When the ultrasonic power was 600 W, the frequency was 30 kHz, and the extraction time was 40 min, the extraction efficiency was the best. Compared with the traditional extraction method, the extraction efficiency of the target components was increased by 30%. Under these conditions, the contents of the main efficacy components in the extract reached a relatively high level. The content of cineole in the volatile oil of Artemisia argyi was 5 mg / g, and the content of camphor was 3 mg / g; the content of cedrol in Platycladus orientalis seeds was 4 mg / g, which could effectively ensure the efficacy of the incense beads, as shown in Table 4 below.

[0169] Table 4 Influence of ultrasonic-assisted extraction on the extraction efficiency

[0170] Extraction method Extraction time (minutes) Extraction rate (%) Purity of the extract (%) Traditional extraction 120 65 82 Ultrasound-assisted extraction 60 85 88

[0171] Note: The extraction rate and purity were analyzed by high performance liquid chromatography (HPLC).

[0172] The present invention has successfully developed an incense product with the efficacy of Miao medicine. The recycled traditional Chinese medicine residue material meets environmental protection standards, has a long-lasting fragrance and does not release harmful substances. By adopting the original preparation of traditional Chinese medicine residue substrate and directional extraction technology of Miao medicine, the in-depth integration of intangible cultural heritage skills and Miao medicine culture has been achieved. The technology of recycling traditional Chinese medicine residues can be popularized to traditional Chinese medicine production enterprises to contribute to green and sustainable development.

[0173] Table 5 Market acceptance of incense beads

[0174]

[0175] Note: The user satisfaction and purchase intention were counted through market research questionnaires.

[0176] As shown in Table 5, the incense bead products of the present invention can be applied to multiple scenarios such as home fragrance, personal wearing, and cultural gifts, and have a wide range of market demands. The products have both efficacy, environmental protection and cultural added value. The technical solutions have the value of industrial promotion. At the same time, through productization, the inheritance and development of Miao medicine and the ancient incense-making skills are promoted.

Claims

1. A preparation method of Miao medicine fragrant beads, characterized in that: It includes the following steps: Step 1. Pretreat traditional Chinese medicinal materials: a. Cleaning: Rinse the recycled and used traditional Chinese medicinal materials with clean water to remove sediment and impurities; b. Drainage: Drain the water from the cleaned traditional Chinese medicinal materials, and then dehydrate them with a centrifuge to avoid mildew caused by excessive moisture during subsequent drying; Step 2. Dry traditional Chinese medicinal materials: Adopt a low-temperature segmented drying process. During the drying process, maintain the low humidity of the hot air through dehumidification technology to improve the drying efficiency. The specific operations are as follows: The first stage: Use hot air at a relatively low temperature to pre-dry the material to reduce the moisture content of the material to a certain extent; The second stage: Further dry under the combined action of microwave and hot air; The third stage: Use hot air for drying again until the material reaches the required final moisture content requirement; Step 3. Crush traditional Chinese medicinal materials: Adopt an ultrafine crushing process. The specific operations are as follows: (1) Preparation work: Prepare the traditional Chinese medicinal materials to be crushed; Check whether the equipment is normal, whether each component is fastened, and whether the power cord and power plug are normal; Put the traditional Chinese medicinal materials into the hopper, turn on the power switch, and after confirming that the voltage is stable and correct, turn on the power switch; (2) Start crushing: According to the types and crushing requirements of traditional Chinese medicinal materials, adjust the parameters of rotation speed, temperature, and crushing time, press the start button to start working. During the crushing process, observe the working state of the crusher and adjust the parameters to obtain a better crushing effect; (3) Crushing completion: When the crushing time reaches the preset time or reaches the ideal crushing degree, stop working, turn off the power switch, take out the ultrafine powder of the crushed traditional Chinese medicine, and carry out packaging and storage; (4) Cleaning and disinfection: After use, it needs to be cleaned and disinfected. First, clean the residues in the crusher, and then disinfect each component of the crusher with a disinfectant to ensure hygienic safety during the next use; Step 4. Extract the effective components of the Miao medicine prescription: Adopt ultrasonic-assisted extraction method for extraction. The specific operations are as follows: A. Preparation work: Configure Miao medicine materials according to the proportion of the Miao medicine prescription, and crush the Miao medicine materials to increase their surface area for better contact with the extraction solvent; B. Mix the medicine powder and the extraction solvent: Select ethanol as the extraction solvent, mix the crushed medicine powder with ethanol at a ratio of 1:10 g / mL, and put it into a distillation flask; C. Ultrasonic treatment: Place the container containing the sample and ethanol in an ultrasonic water bath or an ultrasonic extractor, set the corresponding parameters for ultrasonic treatment. The ultrasonic power ranges from 200 - 1000 W, and an appropriate power can be selected according to the sample amount and the equipment capacity; The ultrasonic frequency is between 20 - 40 kHz, and different frequencies have an impact on the extraction effect, which needs to be adjusted according to specific circumstances; D. Monitoring of the extraction process: During the ultrasonic treatment process, regularly take samples for analysis to monitor the extraction situation of the target components; E. Separation of the extract: After the ultrasonic treatment is completed, first use filter paper or filter cloth to roughly filter the extract to remove medicinal residues and large particle impurities; Then further use a microporous filter membrane for fine filtration to remove fine particles; Finally, centrifuge, put the extract into a centrifuge to separate solid impurities and the supernatant; F. Post-treatment of the extract: The vacuum concentration method is adopted to avoid damaging the thermosensitive components in traditional Chinese medicine at high temperature. Pour the extract into the evaporation flask of the rotary evaporator; set the water bath temperature, turn on the vacuum pump, reduce the system pressure, and evaporate the solvent at a lower temperature. Collect the concentrated solution until the required volume or concentration is reached; Step Five: Making fragrant beads: 1) Powder mixing: Sieve the medicinal powder and Phoebe zhennan powder with a ratio of 7:3 through a 1500-mesh sieve and mix them evenly; 2) Adding the extract and mixing: Add the extracted Miao medicine extract to the mixture. The ratio of the mixture to the extract is 1:

1. Stir while adding and knead the mixture into a uniform dough-like state, ensuring that there is no dry powder or excessive moisture, and it is appropriate that it can be kneaded into a ball and does not stick to the hands; 3) Shaping: Seal the dough-like mixture with plastic wrap and ferment it for 1 hour. Take an appropriate amount of the mixture and roll it into small balls with a diameter of 1 - 1.5 cm, ensuring that the surface of the fragrant beads is smooth and has no cracks; Fill the mixture into the mold, compact it and then demold it to obtain fragrant beads with regular shapes. If there are cracks on the surface of the fragrant beads, moisten your fingers with a small amount of water and gently smooth them; 4) Natural drying: Place the shaped fragrant beads on a drying rack and let them dry naturally in a ventilated and shady place. The drying time is 3 - 5 days, depending on the specific environment; 5) Sanding, polishing and waxing: The surface of the dried fragrant beads may be slightly rough. Gently sand them with fine sandpaper of 800 - 1000 meshes to make the surface smooth, wipe the fragrant beads with a polishing board to make the surface shiny, and finally apply wood wax oil to prevent insects and moisture; Step Six: Processing the finished product: Package the made fragrant beads into fragrant bead bracelets, necklaces, hairpins, hair clips, etc. to improve the aesthetics and commercial value; Step Seven: Storage: Put the fragrant products into a sealed bag or sealed jar and store them in a cool and dry place.

2. The preparation method of the Miao medicine fragrant beads according to claim 1, wherein: In the drying of traditional Chinese medicine in Step Two, in the first stage, hot air with a temperature of 40 - 60 °C is used to pre-dry the material, and the duration is 15 - 30 min.

3. The preparation method of the Miao medicine fragrant beads according to claim 1, characterized in that: In the drying of traditional Chinese medicine in Step Two, in the second stage, the material is further dried under the combined action of microwave with a frequency of 2000 - 3000 MHz and hot air with a temperature of 40 - 60 °C, and the duration is 10 - 15 min.

4. The preparation method of the Miao medicine fragrant beads according to claim 1, characterized in that: In the drying of traditional Chinese medicine in Step Two, in the third stage: Hot air with a temperature of 40 - 55 °C is used for drying again, and the duration is 10 - 15 min until the material meets the requirement of the final moisture content ≤ 5%.

5. The preparation method of the Miao medicine fragrant beads according to claim 1, wherein: In the pulverization of traditional Chinese medicine in Step Three, the preset pulverization time is 30 min, and the pulverization particle size requirement reaches 1250 - 2000 meshes.

6. The preparation method of the Miao medicine fragrant beads according to claim 1, wherein: In the extraction of the effective components of the Miao medicine prescription in Step Four, the extraction conditions are as follows: The extraction time is: 10 - 60 min; The extraction temperature is: usually between room temperature and 80 °C to prevent the loss of thermosensitive components due to temperature, and multiple extractions are carried out to improve the extraction rate.

7. The preparation method of the Miao medicine fragrant beads according to claim 1, characterized in that: In the extraction of the effective components of the Miao medicine prescription in Step Four, the extraction liquid is separated by a microporous membrane with a pore size of 0.22 - 0.45 μm, and the extraction liquid is centrifuged at 3000 - 5000 rpm in a centrifuge for 10 - 15 min.

8. The preparation method of the Miao medicine fragrant beads according to claim 1, characterized in that: In the extraction of the effective components of the Miao medicine prescription in Step Four, the water bath temperature for the post-treatment of the extraction liquid is 40 °C - 60 °C.

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