Pulse ablation guide wire
By integrating the conductive wrap and electrode set on the guide wire, the combination of guidance and pulse discharge ablation is achieved, and the problem of existing guide wires needing to cooperate with the ablation catheter is solved, which improves surgical efficiency and reduces patient pain.
Patent Information
- Application Number
- CN202510683860.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-26
- Publication Date
- 2025-07-22
AI Technical Summary
Existing guidewires only have a guiding role in interventional therapy and need to be used with pulsed electric field ablation catheters, resulting in low surgical efficiency and increased patient pain.
A pulse ablation guide wire is designed, including a central steel wire, a conductive wound body and an electrode group. The conductive wound body is connected to the positive and negative electrode wires, and the electrode group is arranged at the distal end of the guide wire to achieve the combination of guidance and pulse discharge ablation functions.
It simplifies the use of equipment, improves surgical efficiency, and reduces the pain and risks of patients.
Smart Images
Figure CN120346434A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of interventional medical devices, and in particular to a pulse ablation guidewire. Background Art
[0002] In interventional treatment applications, interventional medical devices are receiving more and more attention and are gradually being widely promoted and applied. The distal part of the device is the front working part of the entire interventional medical device. When working, the distal part is delivered to the patient's position to be treated with the help of the channel established in the body, such as the catheter ablation device for treating atrial fibrillation.
[0003] Atrial fibrillation is the most common arrhythmia. Catheter ablation is an important means to restore and maintain sinus rhythm in patients with atrial fibrillation. In clinical practice, pulsed electric field ablation catheters require the use of auxiliary consumables, such as guide wires. The guide wire is first extended from outside the body to the lesion site, and then the pulsed electric field ablation catheter is sent to the lesion site along the pathway established by the guide wire for treatment.
[0004] The existing guide wire only has a guiding function and does not have the pulse discharge treatment function. The guide wire and pulse electric field ablation catheter need to be used in combination and enter the human body in sequence, which not only affects the efficiency of the operation, but is also painful for the patient and increases the risk. Summary of the invention
[0005] The purpose of the present invention is to provide a pulse ablation guidewire to solve the technical problem that the guidewire used in the pulse electric field ablation treatment process in the prior art can only play a guiding role and requires a separate ablation catheter to be inserted, resulting in low surgical efficiency and inconvenient operation.
[0006] The technical problem to be solved by the present invention can be achieved by the following technical solutions:
[0007] The pulse ablation guide wire comprises a central steel wire and a developing ring, wherein a fixed tail end is fixedly installed at the proximal end of the central steel wire, and further comprises:
[0008] A conductive winding body, the conductive winding body is arranged outside the central steel wire, a power supply wire is arranged on the side of the fixed tail end away from the central steel wire, the power supply wire includes a positive wire and a negative wire, and the power supply wire is used for external discharge treatment equipment; the power supply wire is electrically connected with the conductive winding body;
[0009] The electrode group is arranged at a position of the conductive winding body close to the distal end of the central steel wire. The conductive winding body is used to set the electrode group at an exposed position, and the remaining positions are insulated. The power supply wire supplies power to the electrode group through the conductive winding body.
[0010] Preferably, the electrode group includes a bare electrode and a distal head electrode. The conductive winding body is a single conductive wire. The bare electrode is arranged at a position of the conductive winding body close to the distal end of the central steel wire. The bare electrode is the bare part of the conductive winding body. The distal head electrode is fixedly installed at the distal end of the central steel wire. The bare electrode is electrically connected to the positive wire of the power supply wire through the conductive winding body. The distal head electrode is electrically connected to the negative wire of the power supply wire through the central steel wire.
[0011] Preferably, the bare electrode is a continuous ring.
[0012] Preferably, the developing ring annularly covers the surface of the bare electrode which is a continuous ring.
[0013] Preferably, the bare electrode is a single point-like body.
[0014] Preferably, the bare electrode is multiple point-like bodies.
[0015] Preferably, the conductive winding body includes two conductive wires. The two conductive wires are alternately wound and connected to the outside of the central steel wire. One of the conductive wires is connected to the positive wire, and the other conductive wire is electrically connected to the negative wire. The electrode group includes a bare electrode, and bare electrodes are connected to the ends of the two conductive wires.
[0016] Preferably, the conductive winding body is in the shape of a spring and is wound and attached to the outer wall of the central steel wire.
[0017] Preferably, at least one developing ring is provided and is fixedly arranged on the outer surface of the conductive winding body.
[0018] Preferably, the distal end of the central steel wire is a variable diameter end and the diameter gradually becomes smaller.
[0019] Advantages of the present invention:
[0020] 1. In the present invention, a conductive winding body is wound around the central steel wire, and the positive and negative wires are externally connected by the conductive winding body and the central steel wire, which is convenient for supplying power to the distal head electrode and the bare electrode arranged at the distal end of the guide wire, so as to facilitate pulsed discharge ablation. The guiding function and the discharge ablation function are combined, and there is no need to separately use a guide wire for guiding and an ablation catheter, thus achieving the effects of simplifying the use of equipment, improving the surgical efficiency and reducing the pain of patients.
[0021] 2. In the present invention, the developing ring can be arranged on the outer surface of the conductive winding body and combined with the position where the bare electrode is located, so that it can be used for imaging and discharging.
[0022] 3. The bare electrode of the present invention can be set as a single point-like body, multiple point-like bodies or a continuous ring according to actual use needs, which is convenient for use in different situations. Brief Description of the Drawings
[0023] Figure 1 is a schematic diagram of the overall structure of the present invention;
[0024] Figure 2 is a partial structural schematic diagram when the conductive winding body in the present invention is provided with two conductive wires;
[0025] Figure 3 is a structural schematic diagram when the exposed electrode in the present invention is provided as a single point-like body;
[0026] Figure 4 is a structural schematic diagram when the exposed electrode in the present invention is provided as multiple point-like bodies;
[0027] Figure 5 is a structural schematic diagram of the combination of the developing ring and the exposed electrode in the present invention;
[0028] Figure 6 is a partial structural schematic diagram of the connection between the central steel wire and the fixed tail end in the present invention.
[0029] Description of the Reference Numerals:
[0030] 1, central steel wire; 2, conductive winding body; 3, fixed tail end; 4, positive electrode wire; 5, negative electrode wire; 6, developing ring; 7, exposed electrode; 8, distal head electrode. Detailed Description of the Embodiment
[0031] The following is a detailed description of the specific embodiments of the present invention, but it should be understood that the protection scope of the present invention is not limited by the specific embodiments.
[0032] As Figures 1 - 6 shown, the pulsed ablation guide wire can be used for ablation treatment of diseases such as atrial fibrillation, and can be directly inserted into the body of a living subject for pulsed ablation. The guide wire includes a central steel wire 1 and a developing ring 6. A fixed tail end 3 is fixedly installed at the proximal end of the central steel wire 1. The fixed tail end 3 can be used to externally connect an external handheld instrument or other instruments that need to be connected and supported relatedly, and belongs to the non-invasive part. And the fixed tail end 3 is made of a medical-grade material to ensure harmlessness to the human body; the guide wire also includes a conductive winding body 2 and an electrode group;
[0033] The conductive winding body 2 is arranged outside the central steel wire 1, and the conductive winding body 2 wraps the entire central steel wire 1. A power supply wire is arranged on the side of the fixed tail end 3 away from the central steel wire 1. The power supply wire includes a positive electrode wire 4 and a negative electrode wire 5. The power supply wire is used to externally connect a discharge treatment device; the power supply wire is electrically connected in cooperation with the conductive winding body 2;
[0034] The electrode group is arranged at a position of the conductive winding body 2 close to the distal end of the central steel wire 1; the position of the conductive winding body 2 for arranging the electrode group is an exposed part, and the rest positions except the exposed part are insulated; and the power supply wire supplies power to the electrode group through the conductive winding body 2, which is convenient for ablation.
[0035] The whole guide wire is inserted into the diseased position of the human body through the guiding action of the central steel wire 1, and the position of the guide wire intervention is determined by relying on the imaging ring 6 and the supporting imaging examination equipment, and then the power supply wire is externally connected to the discharge treatment equipment to realize power-on. In this way, the conductive winding body 2 can be used to power the electrode group, and the electrode group discharges to realize pulsed discharge ablation treatment of the diseased position.
[0036] In some specific embodiments, refer to Figure 1 As shown, the electrode group includes an exposed electrode 7 and a distal head electrode 8. The conductive winding body 2 is a single conductive wire. The exposed electrode 7 is arranged at a position of the conductive winding body 2 close to the distal end of the central steel wire 1. The exposed electrode 7 is the exposed part of the conductive winding body 2. The distal head electrode 8 is fixedly installed at the distal end of the central steel wire 1. The central steel wire 1 is a conductor. The exposed electrode 7 is electrically connected to the positive wire 4 of the power supply wire through the conductive winding body 2, and the distal head electrode 8 is electrically connected to the negative wire 5 of the power supply wire through the central steel wire 1. The positive and negative attributes of the exposed electrode 7 and the distal head electrode 8 can be freely switched, that is, the exposed electrode 7 can also be electrically connected to the negative wire 5 through the conductive winding body 2, and the distal head electrode 8 is electrically connected to the positive wire 4 of the power supply wire through the central steel wire 1.
[0037] In some specific embodiments, such as Figure 1 As shown, the exposed electrode 7 is a continuous ring.
[0038] In some specific embodiments, such as Figure 5 As shown, the imaging ring 6 annularly covers the surface of the exposed electrode 7 which is a continuous ring. It can play the roles of imaging and discharging at the same time.
[0039] In some other specific embodiments, such as Figure 2 As shown, the exposed electrode 7 is a single point-shaped body.
[0040] In still some specific embodiments, such as Figure 4 As shown, the exposed electrode 7 is a plurality of point-shaped bodies.
[0041] In some specific embodiments, such as Figure 2As shown, the conductive winding body 2 includes two conductive wires, which are alternately wound and connected to the outside of the central steel wire 1. One of the conductive wires is connected to the positive electrode wire 4, and the other conductive wire is electrically connected to the negative electrode wire 5, that is, the two conductive wires correspond to the positive and negative electrodes respectively. The electrode group includes the exposed electrode 7. In this solution, the distal head electrode 8 is not provided. The ends of the two conductive wires are both provided with the exposed electrode 7, and except for the positions where the exposed electrode 7 is provided, the rest of the positions of the two conductive wires are insulated. In this way, the exposed electrode 7 at the corresponding position can be used as the positive or negative electrode to achieve discharge ablation treatment, that is, only the exposed electrode 7 exists in this solution.
[0042] In some specific implementation schemes, such as Figure 1 As shown, the conductive winding body 2 is in the shape of a spring and is wound and attached to the outer wall of the central steel wire 1, which is convenient for better force application and facilitates the overall pushing and insertion of the guide wire to the corresponding diseased position in the human body.
[0043] In some specific implementation schemes, except for the positions where the exposed electrode 7 is located on the conductive winding body 2, the rest of the parts are insulated. The insulation treatment methods include: coating an insulating lubricating coating, and the coating can be a Teflon coating.
[0044] In some specific implementation schemes, at least one imaging ring 6 is provided and is fixedly arranged on the outer surface of the conductive winding body 2. The imaging ring 6 is made of precious metals with good imaging properties, such as platinum-iridium, gold, silver and other good conductive materials, and the shape is annular; the thickness of the imaging ring 6 is in the micron level, so that the imaging ring 6 can better fit on the surface of the conductive winding body 2 and has good flexibility.
[0045] In some specific implementation schemes, the distal end of the central steel wire 1 is a variable diameter end, and the diameter gradually becomes smaller, which is convenient for interventional insertion.
[0046] In some specific implementation schemes, the central steel wire 1 is made of stainless steel or nitinol.
[0047] In some specific implementation schemes, in order to facilitate the fixed connection between the central steel wire 1 and the fixed tail end 3, a slot matching the proximal diameter of the central steel wire 1 can be opened on the fixed tail end 3, and the proximal end of the central steel wire 1 is inserted into the slot, and the bonding and fixing are realized by injecting medical-grade glue. And some wire grooves can also be opened on the fixed tail end 3 for threading and installing the positive and negative electrode wires.
[0048] To facilitate the understanding of this solution by those skilled in the art, the working principle of this solution will be briefly described below in combination with a specific application scenario:
[0049] The conductive winding body 2 is wound around the outer part of the central steel wire 1. It can be wound with a single conductive wire, or two conductive wires can be alternately and tightly wound around the central steel wire 1. If there are two conductive wires, the two conductive wires of the conductive winding body 2 are respectively electrically connected to the positive electrode wire 4 and the negative electrode wire 5. And the imaging ring 6 is installed on the conductive winding body 2. In this way, when the whole guide wire is inserted into the corresponding position of the human body, the intervention position is determined by relying on the imaging ring 6 provided. Then, power is supplied through the positive electrode wire 4 and the negative electrode wire 5 of the externally connected pulse discharge device, so that the exposed electrodes 7 at the ends of the two conductive wires of the conductive winding body 2 discharge, realizing pulsed ablation treatment;
[0050] If the conductive winding body 2 is a single conductive wire, a distal head electrode 8 is installed at the distal end of the central steel wire 1, so that the distal head electrode 8 is electrically connected to the positive pole of the power supply wire by relying on the central steel wire 1, and the exposed electrode 7 exposed on the conductive winding body 2 is electrically connected to the negative pole of the power supply wire. Then, discharge is carried out to realize pulsed ablation, integrating the functions of guiding and conductive ablation into one body, without the need for an additional catheter, with a simple structure and being easier to enter small parts.
[0051] And this solution also conducts potato pulsed discharge ablation experiments on the samples with different discharge parameters. The experiments show that the guide wire sample can effectively discharge, achieving the expected test effect. The specific data shown in the following charts can be referred to:
[0052]
[0053]
[0054] 3 groups of parameters are set in the experiment, and 3 parallel samples are designed for each group. All ablation targets are obvious and the boundaries are clear;
[0055] As the parameters increase, the ablation depth gradually deepens to 3.5 - 4.7 - 5.1 mm.
[0056] Only several specific embodiments of the present invention are disclosed above. However, the embodiments of the present invention are not limited thereto, and any changes that can be thought of by those skilled in the art should fall within the protection scope of the present invention.
Claims
1. Pulse ablation guide wire, comprising a central wire (1) and a visualization ring (6), wherein a fixed tail end (3) is fixedly installed at the proximal end of the central wire (1), and is characterized in that, Further comprising: A conductive winding body (2), the conductive winding body (2) is disposed outside the central steel wire (1), a power supply wire is disposed on a side of the fixed end (3) away from the central steel wire (1), the power supply wire includes a positive wire (4) and a negative wire (5), and the power supply wire is used for externally connecting a discharge treatment device; the power supply wire is electrically connected in cooperation with the conductive winding body (2); An electrode group, the electrode group is disposed at a position of the conductive winding body (2) close to the distal end of the central steel wire (1), a position of the conductive winding body (2) for disposing the electrode group is an exposed part, and the remaining positions are all insulated, and the power supply wire supplies power to the electrode group through the conductive winding body (2).
2. The pulsed ablation guide wire according to claim 1, wherein The electrode group includes an exposed electrode (7) and a distal head electrode (8), the conductive winding body (2) is a single conductive wire, the exposed electrode (7) is disposed at a position of the conductive winding body (2) close to the distal end of the central steel wire (1), the exposed electrode (7) is an exposed part of the conductive winding body (2), the distal head electrode (8) is fixedly installed at the distal end of the central steel wire (1), the exposed electrode (7) is electrically connected to the positive wire (4) of the power supply wire through the conductive winding body (2), and the distal head electrode (8) is electrically connected to the negative wire (5) of the power supply wire through the central steel wire (1).
3. The pulsed ablation guide wire according to claim 2, wherein, The exposed electrode (7) is a continuous ring body.
4. The pulsed ablation guide wire according to claim 3, wherein, The developing ring (6) annularly covers the surface of the exposed electrode (7) which is a continuous ring body.
5. The pulsed ablation guide wire according to claim 2, wherein The exposed electrode (7) is a single point-shaped body.
6. The pulsed ablation guide wire according to claim 2, characterized in that, The exposed electrode (7) is a plurality of point-shaped bodies.
7. The pulsed ablation guide wire according to claim 1, characterized in that, The conductive winding body (2) includes two conductive wires, the two conductive wires are alternately wound and connected outside the central steel wire (1), one of the conductive wires is connected to the positive wire (4), the other conductive wire is electrically connected to the negative wire (5), the electrode group includes an exposed electrode (7), and exposed electrodes (7) are disposed at the ends of the two conductive wires.
8. The pulsed ablation guide wire according to claim 1, wherein The conductive winding body (2) is in a spring shape and is wound and attached to the outer wall of the central steel wire (1).
9. The pulsed ablation guide wire according to claim 1, wherein, At least one developing ring (6) is provided and is fixedly disposed on the outer surface of the conductive winding body (2).
10. The pulsed ablation guide wire according to claim 1, wherein, The distal end of the central steel wire (1) is a variable diameter end and the diameter gradually becomes smaller.