A user-friendly drug susceptibility testing instrument
By designing a drug sensitivity detector with a drug storage cylinder and ratchet linkage mechanism, the problem of cumbersome drug sensitivity testing operation is solved, enabling rapid drug identification and positioning, simplifying the drug dosing process, improving efficiency and reducing the risk of contamination, and making it suitable for use in a constant temperature chamber.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-21
- Publication Date
- 2026-04-03
AI Technical Summary
Existing drug sensitivity testing procedures are cumbersome, time-consuming, and labor-intensive, especially when placing tablets, which requires frequent twisting of the bottle cap and the use of tweezers.
A drug sensitivity detector was designed, comprising a drug storage cylinder, a limiting protrusion, a sliding cover plate, and a ratchet linkage mechanism. This device enables rapid drug identification and positioning, ensuring accurate single drug addition. It can complete drug addition for multiple culture dishes through mechanical linkage, simplifying the operation process. Furthermore, the drug addition operation is carried out in a constant temperature chamber to reduce the risk of contamination.
It simplifies the operation steps of drug sensitivity testing, improves drug dosing efficiency, reduces the risk of external contamination, ensures the stability of the experimental environment, and does not require an external power supply, making it suitable for long-term stable operation in a constant temperature chamber.
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Figure CN120349864B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of drug sensitivity testing technology, specifically to a drug sensitivity testing instrument that is easy to operate. Background Technology
[0002] Drug susceptibility testing refers to the determination of the sensitivity of microorganisms such as bacteria, fungi, or tumor cells to antibacterial and chemotherapeutic drugs. By detecting the inhibitory effect of drugs on pathogens or cancer cells, it provides a basis for precise clinical drug use.
[0003] Currently, when testing drug sensitivity, the usual method is to first spread the pathogen material evenly on an agar medium, then place the various tablets to be tested in different positions within the medium, and after incubation at a constant temperature for a period of time, determine the drug sensitivity by observing the inhibition zone near the drug. However, when placing the tablets, it is usually necessary to manually loosen multiple bottle caps, then use tweezers to remove the tablets from different bottles and place them on multiple culture media, making the overall operation process cumbersome, time-consuming, and labor-intensive. Summary of the Invention
[0004] The purpose of this invention is to provide a drug sensitivity testing instrument that is easy to operate, so as to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, the present invention provides the following technical solution:
[0006] A user-friendly drug sensitivity testing instrument includes a constant temperature chamber and a dosing assembly. The constant temperature chamber has a door panel on one side, and a storage seat is connected to one side of the door panel. The dosing assembly is located on the top of the constant temperature chamber and includes a support plate. The support plate is mounted on the top of the constant temperature chamber, and a horizontal shaft is fixed to one side of the support plate. A drug storage cylinder is rotatably connected to the outer side of the horizontal shaft, and a support is slidably connected to the lower part of the drug storage cylinder. A drug storage cavity is formed inside the drug storage cylinder, and a sliding cover plate is slidably connected to the outer side of the drug storage cylinder. A partition plate is fitted into one side of the sliding cover plate and is slidably connected to the drug storage cylinder. A drug outlet hole is formed at the top of the sliding cover plate, and a first spring seat is mounted at one end of the sliding cover plate, and the first spring seat is in contact with the drug storage cylinder.
[0007] Furthermore, guide rails are slidably connected to both sides of the placement base, and the guide rails are fixedly connected to the constant temperature box. A culture dish is symmetrically arranged above the placement base, and a top cover is slidably connected to the top of the culture dish.
[0008] Furthermore, the inner top of the constant temperature chamber is symmetrically provided with a drug guide tube, and a slot is opened on one side of the drug storage tube. A limit plate is slidably connected inside the slot, and a magnet is magnetically connected to one end of the limit plate, and the magnet is fixedly connected to the drug storage tube.
[0009] Furthermore, a limiting component is provided on the top of the support plate. The limiting component includes a second spring seat. The second spring seat is placed on the top of the support plate, and one end of the second spring seat is connected to a limiting protrusion. A limiting groove is opened at equal intervals around the middle of the other side of the medicine storage cylinder, and an identification plate is provided at equal intervals around the outer end of the other side of the medicine storage cylinder.
[0010] Furthermore, an adjustment assembly is connected to one side of the door panel. The adjustment assembly includes a slide rod. The slide rod is fixed to one side of the door panel, and a slide seat is slidably connected to the outer side of the slide rod. Magnetic rings are symmetrically arranged on both sides of the slide seat, and the slide seat is slidably connected to the door panel. A connecting rod is rotatably connected to one end of the slide seat, and a toothed plate is rotatably connected to the end of the connecting rod. A guide sleeve is slidably connected to the outer side of the middle part of the toothed plate, and the guide sleeve is fixedly connected to the storage seat.
[0011] Furthermore, a toothed ring is engaged at the top of one end of the toothed plate, and a fixed plate is rotatably connected to one end of the toothed ring. The fixed plate is fixedly connected to the storage seat. A torsion spring shaft is arranged on the other side of the toothed plate, and a first pawl is connected to one end of the torsion spring shaft. A ratchet is provided at the end of the first pawl, and a second pawl is connected to the outer side of one end of the ratchet. The second pawl is rotatably connected to the fixed plate.
[0012] Furthermore, a synchronous shaft is fixed inside the ratchet, and the synchronous shaft is rotatably connected to the placement seat. A bevel gear set is installed at both ends of the synchronous shaft, and a rotating seat is connected to the top of the bevel gear set, and the rotating seat is fitted into the culture dish.
[0013] Furthermore, an obstacle avoidance assembly is connected to one side of the constant temperature chamber, and the obstacle avoidance assembly includes a screw. The screw is threadedly connected to one side of the constant temperature chamber, and a sliding frame is rotatably connected to one end of the screw. The sliding frame is slidably connected to the constant temperature chamber. Baffles are symmetrically arranged on the top of the sliding frame, and the baffles are fixedly connected to the drug delivery cartridge.
[0014] Furthermore, a pressure block is symmetrically arranged on one side of the sliding frame, and a top block is slidably connected to one side of the pressure block. A baffle is fixed to one side of the top block, and the baffle is slidably connected to the top cover.
[0015] Furthermore, a third spring seat is connected to one side of the baffle frame, and the third spring seat is fixedly connected to the top cover. The top of the top cover has equidistant circumferential dosing holes, and the dosing holes correspond one-to-one with the baffle frame.
[0016] The drug sensitivity testing instrument provided by this invention has the following beneficial effects:
[0017] 1. This invention achieves rapid identification and positioning of medicines through the classification and storage design of the medicine storage cylinder and the label plate. During operation, the medicine storage cylinder is rotated to align the target medicine cavity with the medicine guide cylinder. The spring of the limiting protrusion and the limiting groove cooperates to produce a positioning prompt sound. With the push-type separation mechanism of the sliding cover, it is ensured that only one piece of medicine is dropped at a time, and multiple culture dishes are added at the same time. This structure simplifies the traditional steps of picking up the medicine with tweezers and opening the bottle cap, and significantly improves the efficiency of medicine addition. At the same time, the medicine addition operation is carried out in a constant temperature chamber, which effectively reduces the risk of external contamination and maintains the stability of the experimental environment.
[0018] 2. This invention uses a ratchet linkage mechanism to achieve precise angle adjustment of the culture dish. The sliding block drives the toothed plate and toothed ring to mesh and transmit power. With the anti-reverse locking function of the double pawl, it ensures that each push of the sliding block produces an equidistant rotation of one-sixth of the circumference, so that the tablets are evenly distributed and do not interfere with each other. The magnetic ring and connecting block adsorption design enhances the stability of the device after adjustment. Compared with electronic positioning, this mechanical angle control is more resistant to high temperature and high humidity environments and does not require an external power supply. It is especially suitable for long-term stable operation in a constant temperature chamber.
[0019] 3. The screw-driven sliding frame of this invention realizes the linkage control between the drug delivery channel and the baffle. The inclined surfaces of the pressure block and the top block cooperate to trigger the spring reset action of the baffle frame, forming an automatic opening and closing system for the drug delivery hole. This mechanical linkage ensures that the drug delivery hole switches synchronously when the culture dish rotates. At the same time, the baffle's secondary sealing design for the opening of the constant temperature box forms a physical isolation barrier during the non-drug delivery stage, eliminating the need for multiple steps and making it more convenient. Attached Figure Description
[0020] Figure 1 This is a three-dimensional front view schematic diagram of the overall structure of a drug sensitivity testing instrument that is easy to operate according to the present invention;
[0021] Figure 2 This is a schematic diagram of the overall three-dimensional rear view structure of a drug sensitivity testing instrument that is easy to operate according to the present invention;
[0022] Figure 3 This is a three-dimensional structural diagram of the shielding component of a convenient drug sensitivity detector according to the present invention.
[0023] Figure 4 This is a schematic cross-sectional view of the dosing component of a drug sensitivity testing instrument that is easy to operate according to the present invention.
[0024] Figure 5 This is a three-dimensional structural diagram of the sliding cover plate of a drug sensitivity testing instrument that is easy to operate according to the present invention;
[0025] Figure 6 This is a bottom view schematic diagram of the adjustment component of a drug sensitivity detector that is easy to operate according to the present invention.
[0026] Figure 7 This is a three-dimensional structural diagram of the adjustment component of a drug sensitivity testing instrument that is easy to operate according to the present invention.
[0027] Figure 8 This is a schematic diagram of the three-dimensional structure of the toothed ring of a drug sensitivity testing instrument that is easy to operate according to the present invention.
[0028] Figure 9 This invention relates to a convenient drug sensitivity testing instrument. Figure 3 Enlarged structural diagram at point A in the middle.
[0029] In the diagram: 1. Incubator; 2. Door panel; 3. Storage seat; 4. Guide rail; 5. Petri dish; 6. Top cover; 7. Dosing assembly; 701. Support plate; 702. Horizontal axis; 703. Drug storage cylinder; 704. Support; 705. Drug storage chamber; 706. Sliding cover; 707. Partition; 708. Drug outlet; 709. First spring seat; 8. Drug guide cylinder; 9. Slot; 10. Limiting plate; 11. Magnet; 12. Limiting assembly; 1201. Second spring seat; 1202. Limiting protrusion; 1203. Limiting groove; 1204. Identification plate; 13. Adjustment assembly; 1301. Slide rod; 1302, Slide; 1303, Magnetic ring; 1304, Connecting rod; 1305, Gear plate; 1306, Guide sleeve; 1307, Gear ring; 1308, Fixing plate; 1309, Torsion spring shaft; 1310, First pawl; 1311, Ratchet; 1312, Second pawl; 1313, Synchronous shaft; 1314, Bevel gear set; 1315, Rotating seat; 14, Clearance assembly; 1401, Screw; 1402, Sliding frame; 1403, Baffle; 1404, Pressure block; 1405, Top block; 1406, Baffle frame; 1407, Third spring seat; 1408, Dosing hole. Detailed Implementation
[0030] The embodiments of the technical solution of this application will now be described in detail with reference to the accompanying drawings. These embodiments are only used to more clearly illustrate the technical solution of this application and are therefore merely examples, and should not be used to limit the scope of protection of this application.
[0031] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains; the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the application; the terms “comprising” and “having”, and any variations thereof, in the specification, claims, and foregoing description of the drawings are intended to cover non-exclusive inclusion.
[0032] In the description of the embodiments of this application, the term "multiple" refers to two or more (including two), similarly, "multiple sets" refers to two or more (including two sets), and "multiple pieces" refers to two or more (including two pieces).
[0033] In the description of the embodiments of this application, the technical terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the embodiments of this application and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the embodiments of this application.
[0034] In the description of the embodiments of this application, unless otherwise expressly specified and limited, technical terms such as "installation," "connection," "joining," and "fixing" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. For those skilled in the art, the specific meaning of the above terms in the embodiments of this application can be understood according to the specific circumstances.
[0035] Please see Figures 1 to 5 The present invention provides an easy-to-operate drug sensitivity testing instrument, including a constant temperature chamber 1 and a drug dosing assembly 7. A door panel 2 is provided on one side of the constant temperature chamber 1, and a place seat 3 is connected to one side of the door panel 2. Guide rails 4 are slidably connected to both sides of the place seat 3, and the guide rails 4 are fixedly connected to the constant temperature chamber 1. A culture dish 5 is symmetrically arranged above the place seat 3, and a top cover 6 is slidably connected to the top of the culture dish 5. The drug dosing assembly 7 is located on the top of the constant temperature chamber 1.
[0036] In some embodiments, the dosing assembly 7 includes a support plate 701. The support plate 701 is mounted on the top of the constant temperature chamber 1, and a horizontal shaft 702 is fixed on one side of the support plate 701. A storage cylinder 703 is rotatably connected to the outer side of the horizontal shaft 702, and a support 704 is slidably connected to the lower part of the storage cylinder 703. A storage cavity 705 is opened inside the storage cylinder 703, and a sliding cover plate 706 is slidably connected to the outer side of the storage cylinder 703. A partition plate 707 is fitted on one side of the sliding cover plate 706, and the partition plate 707 is slidably connected to the storage cylinder 703. A dispensing hole 708 is opened on the top of the sliding cover plate 706, and a first spring seat 709 is mounted on one end of the sliding cover plate 706, and the first spring seat 709 is in contact with the storage cylinder 703.
[0037] A medicine guide tube 8 is symmetrically arranged on the top inner side of the constant temperature chamber 1. A slot 9 is opened on one side of the medicine storage tube 703, and a limit plate 10 is slidably connected inside the slot 9. A magnet 11 is magnetically connected to one end of the limit plate 10, and the magnet 11 is fixedly connected to the medicine storage tube 703. A limit component 12 is provided on the top of the support plate 701. The limit component 12 includes a second spring seat 1201. The second spring seat 1201 is placed on the top of the support plate 701, and a limit protrusion 1202 is connected to one end of the second spring seat 1201. A limit groove 1203 is opened at equal intervals around the middle of the other side of the medicine storage tube 703, and an identification plate 1204 is provided at equal intervals around the outer end of the other side of the medicine storage tube 703.
[0038] When adding medicine, since the commonly used test tablets are pre-stacked in the storage cavity 705 on the storage cylinder 703, and the name of the medicine is written on the label plate 1204, it is convenient to quickly select the corresponding type of tablet and rotate it to the bottom. During the forceful rotation, the limiting protrusion 1202 will squeeze the second spring seat 1201 under the guidance of the limiting groove 1203.
[0039] When the positions are aligned, the limiting protrusion 1202 will slide into the next limiting groove 1203 and make a clicking sound to remind the personnel that the positions are aligned. At this time, simply press the first spring seat 709, and the partition 707 will be inserted between the two tablets to separate them and prevent too many tablets from falling. When the dispensing hole 708 on the sliding cover 706 is completely aligned with the storage cavity 705, a tablet will fall onto the agar culture medium under the guidance of the drug delivery tube 8.
[0040] After releasing the pressure, the first spring seat 709 will drive the sliding cover 706 to reset, automatically blocking the end of the drug storage cavity 705. Therefore, during the drug addition operation, simply rotate the tablet to be tested downwards and press the first spring seat 709 once to simultaneously add drugs to multiple culture dishes 5, eliminating the need to frequently twist the cap and place it with tweezers, making the operation more convenient. At the same time, the drug addition operation is carried out in the constant temperature chamber 1, effectively isolating external contamination and ensuring the normal progress of the test experiment. Furthermore, the transparent observation windows on the top of the constant temperature chamber 1 and the right side of the drug storage cylinder 703 facilitate the observation of the tablet's fall and storage status. When replenishing the tablet, simply push the limiting plate 10 to slide it out of the slot 9, releasing the blocking of the first spring seat 709. As the first spring seat 709 moves, the blocking of the upper part of the drug storage cavity 705 will be released, facilitating the replenishment of drugs. During installation, the limiting plate 10 can be quickly positioned by using the magnet 11 to attract it, making assembly very convenient.
[0041] Please see Figure 1 , Figures 6 to 8 An adjustment assembly 13 is connected to one side of the door panel 2.
[0042] The adjustment assembly 13 includes a slide rod 1301. The slide rod 1301 is fixed to one side of the door panel 2, and a slide seat 1302 is slidably connected to the outer side of the slide rod 1301. Magnetic rings 1303 are symmetrically arranged on both sides of the slide seat 1302, and the slide seat 1302 is slidably connected to the door panel 2. A connecting rod 1304 is rotatably connected to one end of the slide seat 1302, and a toothed plate 1305 is rotatably connected to the end of the connecting rod 1304. A guide sleeve 1306 is slidably connected to the outer side of the middle part of the toothed plate 1305, and the guide sleeve 1306 is fixedly connected to the storage seat 3. A toothed ring 1307 is engaged at the top of one end of the toothed plate 1305, and a fixing plate 1308 is rotatably connected to one end of the toothed ring 1307. 1308 is fixedly connected to the placement base 3. A torsion spring shaft 1309 is arranged on the other side of the toothed plate 1305. One end of the torsion spring shaft 1309 is connected to a first pawl 1310. A ratchet 1311 is provided at the end of the first pawl 1310. A second pawl 1312 is connected to the outer side of one end of the ratchet 1311. The second pawl 1312 is rotatably connected to the fixing plate 1308. A synchronous shaft 1313 is fixed inside the ratchet 1311. The synchronous shaft 1313 is rotatably connected to the placement base 3. A bevel gear set 1314 is arranged at both ends of the synchronous shaft 1313. A rotating seat 1315 is connected to the top of the bevel gear set 1314. The rotating seat 1315 is fitted into the culture dish 5.
[0043] When it is necessary to adjust the position of the tablet in the culture dish 5, simply move the slide block 1302 to the other end of the slide rod 1301. At this time, the connecting rod 1304 will drive the toothed plate 1305 to slide inside the guide sleeve 1306, so that the toothed ring 1307 rotates inside the fixed plate 1308. At the same time, the torsion spring shaft 1309 will drive the first pawl 1310 to engage with the ratchet 1311. Therefore, when the toothed ring 1307 rotates, it can synchronously drive the ratchet 1311 to rotate, and through the synchronous shaft 1313, the bevel gear set 1314 and the rotating seat 1315, drive the culture dish 5 to rotate one-sixth of a turn, so as to adjust the position of the tablet in the culture dish 5.
[0044] When the slide block 1302 is pushed back, the connecting rod 1304 will pull the toothed plate 1305. At this time, when the toothed ring 1307 rotates in the opposite direction, the second pawl 1312 will engage with the ratchet 1311 under the action of gravity, preventing it from rotating in the opposite direction. The first pawl 1310 will slide between itself and the ratchet 1311, and no transmission will occur. Thus, during use, simply pushing the slide block 1302 back and forth will ensure that the angle of rotation of the culture dish 5 is the same each time, so that the tablets can be evenly distributed on the culture dish 5, reducing interference between the tablets. Furthermore, when the slide block 1302 moves to the end of the slide rod 1301, it can attract the connecting block at the end of the slide rod 1301 through the magnetic ring 1303, which helps to enhance the stability after adjustment.
[0045] Please see Figure 3 and Figure 9 One side of the constant temperature chamber 1 is connected to a clearance assembly 14, which includes a screw 1401. The screw 1401 is threadedly connected to one side of the constant temperature chamber 1, and one end of the screw 1401 is rotatably connected to a sliding frame 1402. The sliding frame 1402 is slidably connected to the constant temperature chamber 1. A baffle 1403 is symmetrically arranged on the top of the sliding frame 1402, and the baffle 1403 is fixedly connected to the drug delivery cartridge 8. A clearance assembly 1402 is symmetrically arranged on one side of the sliding frame 1402. A pressure block 1404 is provided, and a top block 1405 is slidably connected to one side of the pressure block 1404. A baffle 1406 is fixed to one side of the top block 1405, and the baffle 1406 is slidably connected to the top cover 6. A third spring seat 1407 is connected to one side of the baffle 1406, and the third spring seat 1407 is fixedly connected to the top cover 6. The top of the top cover 6 has equidistant circumferential dosing holes 1408, and the dosing holes 1408 correspond one-to-one with the baffle 1406.
[0046] When the screw 1401 is rotated, the sliding frame 1402 slides under the limit of the constant temperature chamber 1, causing the baffle 1403 to align the drug delivery cylinder 8 with the top opening of the constant temperature chamber 1. At the same time, the pressure block 1404 presses the top block 1405, causing the baffle frame 1406 to release its obstruction of the drug delivery hole 1408, allowing the tablet to fall into the culture dish 5 under the guidance of the drug delivery cylinder 8. When the adjusting component 13 rotates the culture dish 5, since the culture dish 5 and the top cover 6 are slidably connected and cannot rotate relative to each other, the top block 1405 can slide outside the pressure block 1404. When block 1404 separates, the third spring seat 1407 will drive the baffle 1406 to reset, automatically blocking the dosing hole 1408. The next top block 1405 will slide along the inclined surface of the pressure block 1404, thereby pushing the baffle 1406 to expose the corresponding dosing hole 1408, realizing automatic opening and closing operation, which is more convenient. After dosing, the screw 1401 can be rotated to move the sliding frame 1402 to the rear of the constant temperature chamber 1. At this time, the pressure block 1404 will separate from the top block 1405, and at the same time, the baffle 1403 will also block the top opening of the constant temperature chamber 1.
[0047] When using the drug sensitivity tester of this application, first mark the side of the culture dish 5 with a marker to facilitate the subsequent differentiation of the tablets placed in that area. Then rotate the screw 1401, and the sliding frame 1402 will slide under the limit of the constant temperature chamber 1, so that the baffle 1403 drives the drug delivery tube 8 to align with the top opening of the constant temperature chamber 1. Then place the agar culture dish 5 coated with the disease material on the rotating seat 1315, and then push the door plate 2. The placement seat 3 will slide into the interior of the constant temperature chamber 1 under the guidance of the guide rail 4. Then turn the handle to lock the door plate 2. At the same time, the pressure block 1404 will squeeze the top block 1405, so that the baffle 1406 will release the obstruction of the drug addition hole 1408.
[0048] Secondly, the corresponding type of tablet can be quickly and easily selected according to the label 1204. The tablet is then rotated downwards. During this rotation, the limiting protrusion 1202, guided by the limiting groove 1203, presses against the second spring seat 1201. When the positions are aligned, the limiting protrusion 1202 slides into the next limiting groove 1203, making a clicking sound to indicate that the position is aligned. At this point, simply pressing the first spring seat 709 will insert the partition 707 between the two tablets. To prevent excessive tablets from falling, and when the dispensing hole 708 on the sliding cover 706 is fully aligned with the storage cavity 705, a tablet will fall onto the agar medium under the guidance of the guide tube 8. After releasing the handle, the first spring seat 709 will drive the sliding cover 706 to reset, which will automatically block the end of the storage cavity 705. The falling and storage status of the tablets can be easily observed through the transparent observation windows on the top of the constant temperature chamber 1 and the right side of the storage tube 703.
[0049] Next, slide block 1302 is moved to the other end of slide rod 1301. At this time, connecting rod 1304 will drive toothed plate 1305 to slide inside guide sleeve 1306, causing toothed ring 1307 to rotate inside fixed plate 1308. At the same time, torsion spring shaft 1309 will drive first pawl 1310 to engage with ratchet 1311. Therefore, when toothed ring 1307 rotates, it can synchronously drive ratchet 1311 to rotate, and through synchronous shaft 1313, bevel gear set 1314 and rotating seat 1315, drive culture dish 5 to rotate one-sixth of a turn, thereby adjusting the placement of tablets in the culture dish. The position inside the culture dish 5. At the same time, when the culture dish 5 rotates, since the culture dish 5 and the top cover 6 are slidably connected and cannot rotate relative to each other, the top block 1405 can be driven to slide outside the pressure block 1404. When the top block 1405 separates from the pressure block 1404, the third spring seat 1407 will drive the baffle 1406 to reset and automatically block the dosing hole 1408. The next top block 1405 will slide along the inclined surface of the pressure block 1404, thereby pushing the baffle 1406 to expose the corresponding dosing hole 1408, realizing the automatic opening and closing operation.
[0050] Then, when the slide block 1302 is pushed back, the connecting rod 1304 will pull the toothed plate 1305. At this time, when the toothed ring 1307 rotates in the opposite direction, the second pawl 1312 will engage with the ratchet 1311 under the action of gravity to prevent it from rotating in the opposite direction. The first pawl 1310 will slide between the ratchet 1311 and will not transmit power. Thus, during use, only the slide block 1302 needs to be pushed back and forth to make the angle of the culture dish 5 the same each time it rotates, so that the tablets can be evenly distributed on the culture dish 5, reducing the interference between the tablets. Furthermore, when the slide block 1302 moves to the end of the slide rod 1301, it can attract the connecting block at the end of the slide rod 1301 through the magnetic ring 1303, which helps to enhance the stability after adjustment.
[0051] Finally, after adding the medicine, the screw 1401 can be rotated to move the sliding frame 1402 to the rear of the interior of the constant temperature chamber 1. At this time, the pressing block 1404 will separate from the top block 1405. At the same time, the baffle 1403 will also block the top opening of the constant temperature chamber 1. After culturing in the constant temperature chamber 1 for a period of time, the culture dish 5 can be taken out to observe the size of the antibacterial zone around the tablet to test the drug sensitivity performance. After multiple uses, when it is necessary to replenish the tablet, simply push the limiting plate 10 to slide it out of the slot 9 to release the obstruction of the first spring seat 709. At this time, as the first spring seat 709 moves, the obstruction of the upper part of the drug storage cavity 705 will be released, making it convenient to replenish the medicine. During installation, the limiting plate 10 can be quickly positioned by using the magnet 11 to attract it, making the assembly very convenient.
[0052] This article uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only for the purpose of helping to understand the method and core ideas of the present invention. The above descriptions are only preferred embodiments of the present invention. It should be noted that due to the limitations of textual expression, while there are objectively infinite specific structures, those skilled in the art can make several improvements, modifications, or changes without departing from the principles of the present invention, and can also combine the above technical features in an appropriate manner. These improvements, modifications, changes, or combinations, or the direct application of the inventive concept and technical solution to other situations without modification, should all be considered within the scope of protection of the present invention.
Claims
1. A user-friendly drug sensitivity testing instrument, characterized in that, The device includes a thermostat and a dosing assembly. The thermostat has a door panel on one side, with a storage base connected to one side of the door panel. The dosing assembly is located on top of the thermostat and includes a support plate. The support plate is mounted on the top of the thermostat, and a horizontal shaft is fixed to one side of the support plate. A storage cylinder is rotatably connected to the outer side of the horizontal shaft, and a support is slidably connected to the lower part of the storage cylinder. The storage cylinder has a storage chamber inside, and a sliding cover is slidably connected to the outer side of the storage cylinder. A partition is fitted into one side of the sliding cover and is slidably connected to the storage cylinder. An outlet is located on the top of the sliding cover. The medicine inlet has a sliding cover plate with a first spring seat at one end, which fits against the medicine storage cylinder. A clearance assembly, including a screw, is connected to one side of the constant temperature chamber. The screw is threadedly connected to one side of the constant temperature chamber, and a sliding frame is rotatably connected to one end of the screw. The sliding frame is slidably connected to the constant temperature chamber. Symmetrically arranged baffles are mounted on the top of the sliding frame and are fixedly connected to the medicine guide cylinder. A pressure block is symmetrically arranged on one side of the sliding frame, and a top block is slidably connected to one side of the pressure block. A baffle frame is fixed to one side of the top block and is slidably connected to the top cover. One side of the baffle frame... A third spring seat is connected to the side and is fixedly connected to the top cover. The top cover has equidistant circumferential dosing holes, each corresponding to a baffle frame. An adjustment assembly is connected to one side of the door panel. The adjustment assembly includes a slide rod. The slide rod is fixed to one side of the door panel, and a slide seat is slidably connected to the outer side of the slide rod. Magnetic rings are symmetrically arranged on both sides of the slide seat, and the slide seat is slidably connected to the door panel. A connecting rod is rotatably connected to one end of the slide seat, and a toothed plate is rotatably connected to the end of the connecting rod. A guide sleeve is slidably connected to the outer side of the middle of the toothed plate, and the guide sleeve is fixedly connected to a storage base. One end of the toothed plate is engaged with a toothed ring, and one end of the toothed ring is rotatably connected to a fixed plate. The fixed plate is fixedly connected to the placement base. A torsion spring shaft is arranged on the other side of the toothed plate. One end of the torsion spring shaft is connected to a first pawl, and the end of the first pawl is provided with a ratchet. A second pawl is connected to the outer side of one end of the ratchet, and the second pawl is rotatably connected to the fixed plate. A synchronous shaft is fixed inside the ratchet, and the synchronous shaft is rotatably connected to the placement base. Both ends of the synchronous shaft are provided with bevel gear sets, and the top of the bevel gear sets is connected to a rotating seat, which is fitted into the culture dish.
2. The drug sensitivity testing instrument that is easy to operate according to claim 1, characterized in that, The two sides of the placement base are slidably connected to guide rails, and the guide rails are fixedly connected to the constant temperature box. A culture dish is symmetrically arranged above the placement base, and a top cover is slidably connected to the top of the culture dish.
3. The drug sensitivity testing instrument that is easy to operate according to claim 2, characterized in that, The constant temperature chamber has symmetrically arranged medicine guide tubes on the top inner side. A slot is opened on one side of the medicine storage tube, and a limit plate is slidably connected inside the slot. A magnet is magnetically connected to one end of the limit plate, and the magnet is fixedly connected to the medicine storage tube.
4. The drug sensitivity testing instrument that is easy to operate according to claim 3, characterized in that, The top of the support plate is provided with a limiting component, which includes a second spring seat. The second spring seat is placed on the top of the support plate, and one end of the second spring seat is connected to a limiting protrusion. A limiting groove is opened at equal intervals around the middle of the other side of the medicine storage cylinder, and an identification plate is provided at equal intervals around the outer end of the other side of the medicine storage cylinder.
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