POCT detection card box and POCT detection equipment

Abstract

The invention belongs to the technical field of POCT detection, and discloses a POCT detection card box and POCT detection device.The POCT detection card box comprises a detection card box body and further comprises a reagent cavity. According to the technical scheme, by arranging a shielding assembly, a first fixing assembly and a second fixing assembly, the whole shielding assembly can be fixed through the design of the first fixing assembly; then, when a reagent needs to be dropwise added into the reagent cavity, the first fixing assembly can be pushed to drive the whole shielding assembly to move outwards, so that the two ends of the second fixing assembly are partially inserted into inner cavities in the two sides of the first fixing assembly; then the first fixing assembly and the shielding assembly are integrally fixed, then a reagent can be smoothly dropwise added into the reagent cavity, and finally the first fixing assembly is pushed to reset, so that the shielding assembly shields and seals the top of the reagent cavity, the reagent in the reagent cavity can be smoothly shielded and sealed, and pollution caused by entering of external dust is avoided.

Description

Technical Field

[0001] The present invention belongs to the technical field of POCT detection, and specifically relates to a POCT detection cartridge and a POCT detection device. Background Art

[0002] POCT detection, which also accounts for an increasingly large proportion in medical examinations, is a subdivision of the IVD (in vitro diagnosis) industry. It refers to rapid diagnosis immediately at the sampling site, eliminating the complex processing of specimens in the laboratory. It is a detection method that uses portable analytical instruments and supporting reagents to quickly obtain detection results. Usually, corresponding POCT detection cartridges and POCT detection devices are used. The POCT detection cartridge mainly consists of a cartridge, a reagent chamber, and a reaction chamber.

[0003] When the POCT detection cartridge is in use, the reagent is directly dropped and stored in the reagent chamber, then flows to the reaction chamber for mixing, and then is placed inside the detection device for real-time detection. However, since the reagent chamber is directly exposed to the outside, dust from the outside will enter when it is idle. Summary of the Invention

[0004] To solve the problems raised in the above background art, the present invention provides a POCT detection cartridge and a POCT detection device, which have the advantage of being convenient for shielding and dust-proofing the idle reagent chamber.

[0005] To achieve the above object, the present invention provides the following technical solution: A POCT detection cartridge includes a detection cartridge body, and further includes: a reagent chamber, which is opened on both sides inside the detection cartridge body; a shielding component, which is movably installed inside the reagent chamber; a first fixing component, which is arranged outside the shielding component; a second fixing component, which is arranged on the top of the detection cartridge body and is located outside the first fixing component; wherein, the first fixing component includes a sliding block fixedly installed outside the shielding component, a first magnet is arranged at the bottom of the inner cavity of the sliding block, and a second magnet is arranged inside the detection cartridge body and is located inside the first magnet; the second fixing component includes a rectangular shell fixedly installed on the outer top of the detection cartridge body, clamping blocks are movably installed on both sides of the inner cavity of the rectangular shell, a lifting column is movably installed in the middle of the inner cavity of the rectangular shell and is located above the inner side of the clamping blocks, a linkage arm is hinged between the two bottom sides of the lifting column and the inner side of the clamping blocks, and the lifting column is elastically connected to the inside of the rectangular shell through a second power spring.

[0006] Preferably, a reaction chamber is opened in the middle of the detection cartridge body, and the outside of the reaction chamber is connected to the reagent chamber through a flow channel.

[0007] Preferably, the shielding component includes a shielding plate, a movable column, a pressing disc and a first power spring; The shielding plate is movably installed at the top of the inner cavity of the reagent chamber. The movable column is movably sleeved in the middle of the shielding plate. The pressing disc is arranged at the bottom end of the movable column. The top of the pressing disc is elastically connected to the bottom of the shielding plate through the first power spring.

[0008] Preferably, the inner wall of the first power spring is slidably connected to the surface of the movable column.

[0009] Preferably, an elliptical groove is formed at the top of the movable column.

[0010] Preferably, the first magnet and the second magnet are identical in size and opposite in magnetic pole.

[0011] Preferably, clamping grooves are formed on both sides of the sliding block, and the size of the clamping grooves is adapted to the inner cavity size of the clamping block.

[0012] Preferably, a one-way valve flap is arranged on the inner side of the inner cavity of the flow channel.

[0013] A PCT detection device further includes a detection instrument, a display screen and a cartridge placement slot, and the diameter of the size of the cartridge placement slot is adapted to the detection cartridge body.

[0014] A POCT detection method is as follows: S1. Sampling: Push the top of the shielding component upward, and then push the first fixing component to drive the whole shielding component outward to release the shielding of the reagent chamber. At this time, the first fixing component and the shielding component are fixed after moving outward through the second fixing component. Then, the reagent sample is dropped into the reagent chamber. S2. Reaction: Push the first fixing component and the shielding component to reset and fix. Then, when the bottom of the shielding component pushes the reagent inside the reaction chamber into the flow channel, it will push the one-way valve flap to flip open and enter the reaction chamber for mixing reaction. S3. Detection: Place the whole detection cartridge body after the mixing reaction into the cartridge placement slot of the detection instrument, and then control the detection instrument to detect the detection cartridge body through the display screen.

[0015] Compared with the prior art, the beneficial effects of the present invention are as follows: Through the above technical solution, by setting the shielding component, the first fixing component and the second fixing component, the overall shielding component can be fixed through the design of the first fixing component, so as to shield and seal the top of the reagent chamber when it is idle. Then, when it is necessary to drop reagents into the reagent chamber, the first fixing component can be pushed to drive the overall shielding component to move outward, so that both ends of the second fixing component are inserted into the inner cavities on both sides of the first fixing component, and then the overall first fixing component and the shielding component are fixed. Subsequently, reagents can be smoothly dropped into the reagent chamber. Finally, the first fixing component is pushed to reset, so that the shielding component shields and seals the top of the reagent chamber, and the reagents in the reagent chamber can be smoothly shielded and sealed to prevent external dust from entering and causing pollution.

[0016] In the present invention, by setting the shielding component and the one-way valve flap, when the shielding component is reset to shield the reagent chamber after dropping reagents, the bottom of the shielding component will be released. At this time, it can assist in squeezing and pushing the reagents inside the reagent chamber through the inside of the flow groove, pushing the one-way valve flap to flip and open to one side. Finally, the reagents inside the reagent chamber can quickly pass through the one-way valve flap unidirectionally and enter the inside of the reaction chamber for mixing reaction, greatly improving the mixing reaction efficiency, and further improving the subsequent detection efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a schematic structural diagram of the present invention; Figure 2 is a sectional structural diagram of the reaction chamber of the present invention; Figure 3 is Figure 2 a partial enlarged structural diagram at A in Figure 4 is a partial sectional structural diagram of the shielding component; Figure 5 is Figure 4 a partial enlarged structural diagram at B in Figure 6 is a structural diagram of the clamping block of the present invention; Figure 7 is a structural diagram of the second fixing component of the present invention.

[0018] In the figure: 1. Detection cartridge body; 2. Reagent chamber; 3. Reaction chamber; 4. Flow groove; 5. Shielding component; 501. Shielding plate; 502. Movable column; 503. Pressing disc; 504. First power spring; 6. First fixing component; 601. Sliding block; 602. First magnet; 603. Second magnet; 7. Second fixing component; 701. Rectangular shell; 702. Clamping block; 703. Lifting column; 704. Linkage arm; 705. Second power spring; 8. One-way valve flap. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0019] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0020] As Figures 1 to 7 shown, the present invention provides a POCT test cartridge, including a test cartridge body 1, and further including: a reagent chamber 2, which is opened on both sides inside the test cartridge body 1; a shielding assembly 5, which is movably installed in the inner cavity of the reagent chamber 2; a first fixing assembly 6, which is arranged outside the shielding assembly 5; a second fixing assembly 7, which is arranged on the top of the test cartridge body 1 and is located outside the first fixing assembly 6; wherein, the first fixing assembly 6 includes a sliding block 601 fixedly installed outside the shielding assembly 5, a first magnet 602 is arranged at the bottom of the inner cavity of the sliding block 601, and a second magnet 603 is arranged inside the test cartridge body 1 and is located inside the first magnet 602; the second fixing assembly 7 includes a rectangular shell 701 fixedly installed on the outer top of the test cartridge body 1, two clamping blocks 702 are movably installed on both sides of the inner cavity of the rectangular shell 701, a lifting column 703 is movably installed in the middle of the inner cavity of the rectangular shell 701 and is located above the inner sides of the clamping blocks 702, a linkage arm 704 is hinged between the two bottom ends of the lifting column 703 and the inner sides of the clamping blocks 702, and the lifting column 703 is elastically connected to the inside of the rectangular shell 701 through a second power spring 705.

[0021] By pushing the sliding block 601 to move to one side, the first magnet 602 and the second magnet 603 will be separated, thereby releasing the overall fixing effect on the sliding block 601. Then, when pushing it outward, the two sides of the sliding block 601 will squeeze and push the inner inclined surfaces of the clamping blocks 702, causing the two clamping blocks 702 to move away from each other. Until the inner ends of the clamping blocks 702 are completely opposite to the outside of the sliding block 601, the elastic force of the second power spring 705 will be released to push the lifting column 703 upward, causing the linkage arm 704 to drive the clamping blocks 702 to move towards each other, so that the inner ends can be smoothly inserted into the inside of the outside of the sliding block 601.

[0022] As Figure 1 and Figure 2 shown, a reaction cavity 3 is opened in the middle of the test cartridge body 1, and the outside of the reaction cavity 3 is communicated with the reagent chamber 2 through a flow channel 4.

[0023] Adopting the above solution: by providing the flow channel 4, when a reagent is dropped into the reagent chamber 2, it will smoothly enter the inside of the flow channel 4 for subsequent entry into the inside of the reaction cavity 3 for mixing reaction.

[0024] As shown Figure 4 in the figure, the shielding component 5 includes a shielding plate 501, a movable column 502, a pressing disc 503 and a first power spring 504; The shielding plate 501 is movably installed at the top inside the reagent chamber 2. The movable column 502 is movably sleeved in the middle of the shielding plate 501. The pressing disc 503 is arranged at the bottom end of the movable column 502. The top of the pressing disc 503 is elastically connected to the bottom of the shielding plate 501 through the first power spring 504.

[0025] With the above solution: By providing the first power spring 504, when the reagent is dropped into the inner cavity of the reagent chamber 2 and the whole shielding plate 501 is reset, the elastic force of the first power spring 504 will be released, thereby pushing the whole pressing disc 503 to move downward as a whole, so as to squeeze the reagent inside the reagent chamber 2.

[0026] As shown Figure 4 in the figure, the inner wall of the first power spring 504 is slidably connected to the surface of the movable column 502.

[0027] With the above solution: When the whole of the first power spring 504 and the pressing disc 503 move, the first power spring 504 can perform telescopic movement in the vertical direction along the surface of the movable column 502.

[0028] As shown Figure 4 in the figure, an elliptical groove is formed at the top of the movable column 502.

[0029] With the above solution: Through the design of the elliptical groove at the top of the movable column 502, the user can smoothly pull the movable column 502 through this position to drive the whole pressing disc 503 to move upward.

[0030] As shown Figure 5 in the figure, the first magnet 602 and the second magnet 603 are completely identical in size and have opposite magnetic poles.

[0031] With the above solution: Due to the design that the first magnet 602 and the second magnet 603 have opposite magnetic poles, they will adsorb each other to fix the whole sliding block 601 and the shielding plate 501.

[0032] As shown Figure 6 in the figure, clamping grooves are formed on both sides of the sliding block 601, and the size of the clamping grooves is adapted to the inner cavity size of the clamping block 702.

[0033] With the above solution: When the elastic force of the second power spring 705 is released to push the whole lifting column 703 downward, the linkage arm 704 drives the clamping block 702 to move towards each other, so that the inner end of the rectangular shell 701 is stuck in the clamping grooves on both sides of the sliding block 601 to fix the sliding block 601 after it moves outward.

[0034] As Figure 3 and Figure 4 shown, a check valve flap 8 is provided on the inner side of the inner cavity of the flow groove 4.

[0035] With the above solution: when the whole of the pressing disk 503 is pushed downward to make the reagent in the reagent chamber 2 enter the flow groove 4, it will squeeze and push the check valve flap 8 to turn over and open unidirectionally, so that the corresponding reagent can smoothly enter the reaction cavity 3 for internal mixing.

[0036] A POCT detection device further includes a detection instrument, a display screen and a cartridge placement slot, and the size diameter of the cartridge placement slot is adapted to the detection cartridge body 1.

[0037] A POCT detection method is as follows: S1. Sampling: Push the top of the shielding assembly 5 upward, and then push the first fixing assembly 6 to drive the whole of the shielding assembly 5 outward to release the shielding of the reagent chamber 2. At this time, the first fixing assembly 6 and the shielding assembly 5 are fixed after moving outward by the second fixing assembly 7, and then the reagent sample is dropped into the reagent chamber 2; S2. Reaction; Push the first fixing assembly 6 and the shielding assembly 5 to reset and fix. After that, when the bottom of the shielding assembly 5 pushes the reagent in the reaction cavity 3 into the flow groove 4, it will push the check valve flap 8 to turn over and open and enter the reaction cavity 3 for mixing reaction; S3. Detection; Place the whole detection cartridge body 1 after the mixing reaction into the cartridge placement slot of the detection instrument, and then control the detection instrument to detect the detection cartridge body 1 through the display screen.

[0038] The working principle and usage process of the present invention: First, when the user needs to drop the reagent into the reagent chamber 2, the movable column 502 can be pulled to drive the whole of the pressing disk 503 to move upward, and then the sliding block 601 can be pushed to move outward as a whole, so that the first magnet 602 and the second magnet 603 are separated, thereby releasing the magnetic attraction fixing effect on the sliding block 601. After that, when moving outward, the two sides of the sliding block 601 will contact the inner inclined surface of the clamping block 702, and then the whole clamping block 702 will be pushed away from each other, and the linkage arm 704 will deflect to drive the whole lifting column 703 to move downward, and at the same time compress the second power spring 705.

[0039] Afterwards, when the inner end part of the clamping block 702 is exactly aligned with the clamping grooves on both sides of the sliding block 601, the elastic force of the second dynamic spring 705 will be smoothly released, thereby pushing the entire lifting column 703 downward. Furthermore, the linkage arm 704 will deflect to drive the two clamping blocks 702 to move towards each other, enabling the inner ends of the clamping blocks 702 to be smoothly stuck in the clamping grooves on both sides of the sliding block 601, thus fixing the entire sliding block 601 and the shielding plate 501. Then, the reagent can be dropped into the corresponding reagent chamber 2. Since there are multiple reagent chambers 2 designed, different reagents can be dropped respectively.

[0040] Finally, by pushing the entire lifting column 703 downward, the linkage arm 704 can be deflected to push the clamping blocks 702 to move away from each other, causing the inner sides of the clamping blocks 702 to disengage from the clamping grooves on both sides of the sliding block 601, thus releasing the fixing effect on the entire sliding block 601. Subsequently, by pushing the sliding block 601, the entire shielding plate 501 can be driven to move inward, causing the first magnet 602 and the second magnet 603 to contact and magnetically fix the sliding block 601. Meanwhile, the shielding plate 501 completely shields the reagent on the top of the reagent chamber 2. At the same time, the elastic force of the first dynamic spring 504 will be released, further pushing the entire movable column 502 and the pressing plate 503 downward. Finally, the reagent in the inner cavity of the reagent chamber 2 is squeezed and pushed through the flow channel 4 to push the one-way valve flap 8 to open unidirectionally and enter the interior of the reaction cavity 3 for mixing reaction. After that, the entire detection cartridge body 1 can be placed in the cartridge placement groove inside the detection instrument, and then the display screen can be used to control the detection instrument to perform the detection operation.

[0041] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or sequence between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements not only includes those elements, but also includes other elements not expressly listed, or elements inherent to such process, method, article or device.

[0042] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A POCT detection cartridge, comprising a detection cartridge body (1), characterized in that: It further includes: A reagent chamber (2), which is provided on both sides inside the detection cartridge body (1); A shielding component (5), which is movably installed in the inner cavity of the reagent chamber (2); A first fixing component (6), which is arranged outside the shielding component (5); A second fixing component (7), which is arranged on the top of the detection cartridge body (1) and is located outside the first fixing component (6); Among them, the first fixing component (6) includes a sliding block (601) fixedly installed outside the shielding component (5), a first magnet (602) is arranged at the bottom of the inner cavity of the sliding block (601), and a second magnet (603) is arranged inside the detection cartridge body (1) and is located inside the first magnet (602); The second fixing component (7) includes a rectangular shell (701) fixedly installed on the outer top of the detection cartridge body (1), clamping blocks (702) are movably installed on both sides of the inner cavity of the rectangular shell (701), a lifting column (703) is movably installed in the middle of the inner cavity of the rectangular shell (701) and is located above the inner sides of the clamping blocks (702), a linkage arm (704) is hinged between the two sides of the bottom end of the lifting column (703) and the inner sides of the clamping blocks (702), and the lifting column (703) is elastically connected to the inside of the rectangular shell (701) through a second power spring (705).

2. The POCT test cartridge according to claim 1, wherein: A reaction cavity (3) is opened in the middle of the detection cartridge body (1), and the outer side of the reaction cavity (3) is connected to the reagent chamber (2) through a flow-through groove (4).

3. The POCT test cartridge according to claim 1, wherein: The shielding component (5) includes a shielding plate (501), a movable column (502), a pressing plate (503) and a first power spring (504); The shielding plate (501) is movably installed on the top of the inner cavity of the reagent chamber (2), the movable column (502) is movably sleeved in the middle of the shielding plate (501), and the pressing plate (503) is arranged at the bottom end of the movable column (502).

4. The POCT test cartridge according to claim 3, wherein: The top of the pressing plate (503) is elastically connected to the bottom of the shielding plate (501) through a first power spring (504).

5. The POCT test cartridge according to claim 4, wherein: The inner wall of the first power spring (504) is slidably connected to the surface of the movable column (502).

6. The POCT test cartridge according to claim 4, wherein: An elliptical groove is opened at the top of the movable column (502).

7. The POCT test cartridge according to claim 1, wherein: The first magnet (602) and the second magnet (603) are exactly the same in size and have opposite magnetic poles.

8. The POCT test cartridge according to claim 1, wherein: Slots are opened on both sides of the sliding block (601), and the size of the slots is adapted to the size of the inner cavity of the clamping block (702).

9. The POCT test cartridge according to claim 2, wherein: A one-way valve flap (8) is arranged on the inner side of the inner cavity of the flow-through groove (4).

10. A POCT detection device, characterized in that, It includes the POCT detection cartridge according to any one of claims 1-8, and further includes a detection instrument, a display screen and a cartridge placement slot, and the diameter of the size of the cartridge placement slot is adapted to the detection cartridge body (1).

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