A lung tumor treatment device based on irreversible electroporation and cryoablation
By designing a lung tumor treatment device that combines a single needle and an ice knife, and utilizing CT guidance and temperature sensors, the problems of inconvenient operation and tissue damage in the treatment of lung ground-glass nodules have been solved, enabling precise treatment and outcome assessment.
Patent Information
- Application Number
- CN202510790396.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-13
- Publication Date
- 2026-01-02
- Estimated Expiration
- 2045-06-13
AI Technical Summary
Existing irreversible electroporation and cryoablation techniques for treating pulmonary ground-glass nodules present problems such as inconvenience of operation, significant tissue damage, and difficulty in confirming treatment efficacy.
A lung tumor treatment device based on irreversible electroporation and cryoablation is designed, combining a single needle and an ice knife, guided by a CT display module, and providing an operating channel through a puncture cannula. It integrates a data acquisition mechanism and a temperature sensor to achieve precise treatment and tissue collection.
It improves the accuracy of treatment positioning, reduces damage to surrounding tissues, provides real-time temperature monitoring and treatment outcome assessment, and ensures the clearance effect of pulmonary ground-glass nodules.
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Figure CN120458703B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of medical devices, in particular to a lung tumor treatment device based on irreversible electroporation and cryoablation. BACKGROUND
[0002] Pulmonary ground glass nodule is a cloud-like shadow with slightly increased density in chest CT, which is nodular (usually ≤3cm in diameter), and the nodule is named after the ground glass due to its similarity to ground glass. It may be a benign or early tumor of malignant lesion.
[0003] In the treatment of early tumors, in addition to direct surgical resection, irreversible electroporation ablation technology or cryoablation technology can be used for patients who cannot tolerate surgery or require palliative treatment. Among them, the traditional irreversible electroporation ablation technology usually uses multiple electrode needles to form an electric field to cover the tumor area, and applies a short-time, high-intensity electric pulse to the tumor tissue to form an irreversible nanoscale pore on the cell membrane. Unlike traditional radiofrequency and microwave thermal ablation, irreversible electroporation ablation technology does not rely on high temperature, but directly damages the cell membrane through the electric field, avoiding damage to the surrounding blood vessels, nerves and bronchi caused by thermal damage. Cryoablation technology is a minimally invasive treatment technology that destroys tumor tissue through extremely low temperature. By delivering liquid nitrogen or argon gas to the tumor tissue through a probe, a "nitrogen argon knife" is formed, and the temperature can be reduced to -140℃ to -160℃, rapidly freezing tumor cells, and causing ice crystals to form inside the cells, directly damaging the cell membrane and organelle structure. However, the formation of ice crystals may tear the surrounding tissues such as blood vessels and cause bleeding. Secondly, cryoablation usually cannot obtain complete tumor tissue specimens, making it difficult to confirm whether the tumor has been completely inactivated through postoperative pathology, and there is a risk of recurrence, but the release of tumor antigens by cryoablation can enhance the systemic immune response.
[0004] At the same time, since irreversible electroporation ablation technology and cryoablation technology both need to be guided under CT images, the traditional irreversible electroporation ablation technology uses multiple needle punctures, which has a large puncture area and is not convenient for single-person operation, and is not suitable for small disease pulmonary ground glass nodules. Therefore, a single-needle bipolar electrode technology can be used to reduce tissue damage. However, high voltage may cause muscle spasm in the treatment area, and anesthesia is usually required to control muscle spasm, while the low temperature generated by cryoablation technology can temporarily paralyze nerves, and the analgesic effect during the operation is significant. The combination of the two can reduce the amount of anesthetic used by the patient during the operation, reduce the risk of side effects for the patient, and speed up postoperative recovery.
[0005] Moreover, the irreversible electroporation ablation technology is derived from the physical damage (electroporation effect) of the electric field to the cell membrane, rather than thermal energy, but part of the electric energy is converted into heat energy (Joule heat) due to the existence of the resistance of the surrounding tissue when the electric current passes through the surrounding tissue, resulting in slight temperature rise, which can enhance the cell membrane brittleness of the cryoablation technology and improve the electroporation efficiency; and the reheating formed by the irreversible electroporation ablation technology is used to further tear the cell membrane and destroy the tumor tissue. Therefore, the application provides a lung tumor treatment device based on irreversible electroporation and cryoablation, which facilitates the treatment of lung ground glass nodules by using a single needle for generating high-voltage electric pulses and a nitrogen-argon knife for delivering cold gas alone or in combination, guarantees the treatment effect, and reduces the damage to the surrounding tissue in the body during the treatment of lung ground glass nodules. SUMMARY
[0006] To solve the above problems, the application provides a lung tumor treatment device based on irreversible electroporation and cryoablation, which facilitates switching tools and reduces damage to the surrounding tissue in the body during the treatment of lung ground glass nodules, and guarantees the removal effect of lung ground glass nodules.
[0007] To achieve the above-mentioned purposes, the technical scheme of the application is as follows: a lung tumor treatment device based on irreversible electroporation and cryoablation, comprising a single needle for generating high-voltage electric pulses, an ice knife for delivering cold gas medium, and a CT display module for displaying CT images in real time, comprising a puncture sleeve, a sliding groove is formed in the puncture sleeve, and the single needle and the ice knife are gap-fitted with the sliding groove.
[0008] A needle head is detachably connected in the sliding groove, a delivery pipe is communicated in the puncture sleeve, and an outlet for discharging cold gas medium is formed at one end of the puncture sleeve.
[0009] One side of the sliding groove is also communicated with a collection mechanism for collecting external tissue, and the collection mechanism is used to collect external tissue based on the pushing of the needle head, the single needle and the ice knife.
[0010] Further, the collection mechanism comprises a mounting piece slidingly fitted with the puncture sleeve, a deformable stretching piece is slidingly fitted at the center of the mounting piece, one end of the stretching piece is hinged to one end of the mounting piece close to the outlet, the stretching piece is slidingly fitted with the mounting piece, a rubber block is fixedly connected to one side of the stretching piece away from the puncture sleeve, the top of the rubber block is a vertical surface, and the bottom of the rubber block is an arc surface.
[0011] The end of the single needle, the ice knife and the needle head close to the outlet is provided with a matching groove.
[0012] Further, a plurality of scraping teeth are fixedly connected to both sides of the stretching piece.
[0013] Further, the spring is fixedly connected between the end of the stretching sheet away from the output port and the mounting sheet, the mounting sheet is fixedly connected with the shielding sheet at the end close to the output port, the shielding sheet is located between the center of the stretching sheet and the puncture sleeve, and the collecting groove is opened on the side of the shielding sheet close to the stretching sheet.
[0014] The bimetallic sheet is arranged between the rubber block and the stretching sheet, one end of the bimetallic sheet is located in the rubber block, the other end of the bimetallic sheet is located in the stretching sheet, and the thermal expansion coefficient of the end of the bimetallic sheet close to the output port is greater than the thermal expansion coefficient of the end of the bimetallic sheet away from the output port.
[0015] Further, the electromagnet is fixedly connected on the side of the single needle close to the matching groove, and the electromagnet is used for working based on generation of high-voltage electric pulses.
[0016] When the electromagnet works, the electromagnet abuts against the rubber block.
[0017] Further, the temperature sensor is fixedly connected on the side of the stretching sheet away from the puncture sleeve, and the temperature sensor is used for measuring temperature data of the surrounding tissue in real time and sending the temperature data to the CT display module.
[0018] The CT display module is electrically connected with the processing module, the processing module is used for recording the temperature data in real time and recording a surgical procedure corresponding to the current time, the surgical procedure includes normal body temperature data in a needle puncture process, first reference data corresponding to an irreversible electroporation treatment process and second reference data corresponding to a cryoablation treatment process, comparing the temperature data with temperature data corresponding to the surgical procedure of the current time, if the current time is the needle puncture process, marking the temperature data of the current time as the normal body temperature data; if the current time is the irreversible electroporation treatment process, comparing the temperature data with the first reference data, if they are consistent, sending a continuous treatment display instruction to the CT display module, if they are not consistent, sending a continuous stop display instruction to the CT display module; if the current time is the cryoablation treatment process, comparing the temperature data with the second reference data, if the temperature data is greater than or equal to the second reference data, sending an ablation completion instruction to the CT display module; if the temperature data is less than the second reference data, sending an unfreezing completion instruction to the CT display module.
[0019] Further, the delivery tube in the puncture sleeve is located around the mounting sheet.
[0020] Further, the mounting sheet is fixedly connected with the clamping block at the end close to the puncture sleeve, and the end of the matching groove away from the stretching sheet is arc-shaped.
[0021] Further, the puncture sleeve is provided with the isolation layer at the end close to the output port.
[0022] Further, the conveying pipe is communicated with a plurality of electromagnetic valves on the side close to the puncture sleeve, the electromagnetic valves are electrically connected with the processing module, and the electromagnetic valves are evenly arranged in the length direction of the mounting sheet.
[0023] The above scheme has the following beneficial effects:
[0024] 1. In the CT ultrasound image display process, irreversible electroporation and cryoablation are guided to ensure the positioning accuracy in the treatment of lung ground glass nodules, the puncture sleeve provides an operation channel, the single needle and the ice knife are conveniently transported according to the needs, the damage of repeated puncture to the patient is reduced, repeated sampling is facilitated, and a basis for judging the treatment result is provided.
[0025] 2. In the treatment process, the conveying pipe is used to maintain the temperature of the tissue collected by the collecting mechanism, so that the influence of the deformation of the treated tissue due to temperature change is reduced, the destructiveness to the original tissue is reduced, a reference basis for the doctor to understand the tissue before and after treatment is provided, and the parameters in the operation are facilitated to be controlled.
[0026] 3. In the treatment process, the stretching sheet is stretched to contact and process the surrounding tissue to form an additional supporting effect to maintain the fixing effect of the puncture sleeve, so that the movement in the process of replacing the single needle or the ice knife is reduced, and the consistency in the treatment process is maintained.
[0027] Additional aspects and advantages of the application will be made apparent from the following description. BRIEF DESCRIPTION OF DRAWINGS
[0028] Figure 1 is a perspective view of an embodiment of the lung tumor treatment device based on irreversible electroporation and cryoablation of the application;
[0029] Figure 2 is a top view of Figure 1 ;
[0030] Figure 3 is a sectional view of A-A in Figure 2 ;
[0031] Figure 4 is an enlarged view of part B in Figure 3 ;
[0032] Figure 5 is an ice knife installation schematic diagram of an embodiment of the lung tumor treatment device based on irreversible electroporation and cryoablation of the application;
[0033] Figure 6 is a single needle installation schematic diagram of an embodiment of the lung tumor treatment device based on irreversible electroporation and cryoablation of the application;
[0034] Figure 7 Intraoperative CT image schematic diagram of the puncture cannula of the lung tumor treatment device based on irreversible electroporation and cryoablation of the present application;
[0035] Figure 8 Postoperative healing CT image schematic diagram of the lung tumor treatment device based on irreversible electroporation and cryoablation of the present application.
[0036] The reference signs in the drawings of the specification include: 1, puncture cannula; 11, sliding groove; 12, output port; 13, delivery tube; 2, needle; 3, stretching piece; 30, mounting piece; 31, rubber block; 32, shielding piece; 4, single needle; 5, ice knife; 51, exhaust pipe; 6, matching groove; 61, electromagnet; 62, bimetallic strip. DETAILED DESCRIPTION
[0037] The technical solutions of the present application will be described in detail below with reference to the drawings. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.
[0038] In the description of the present application, it should be noted that the orientations or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application. In addition, the terms "first", "second", "third" are only for descriptive purposes and cannot be understood as indicating or implying relative importance.
[0039] In the description of the present application, it should be noted that unless otherwise explicitly specified and limited, the terms "mounting", "connection", "connection" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.
[0040] The specific embodiments will be described in further detail below:
[0041] Embodiment 1:
[0042] As shown in the accompanying drawings Figures 1 to 6As shown: a lung tumor treatment device based on irreversible electroporation and cryoablation, including a single needle 4 for generating high-voltage electric pulses, an ice knife 5 for delivering cold gas medium, and a CT display module for displaying CT images in real time, including a puncture sleeve 1, a sliding groove 11 is opened in the puncture sleeve 1, and the single needle 4 and the ice knife 5 are gap-fitted with the sliding groove 11;
[0043] The needle 2 is detachably connected in the sliding groove 11, the puncture sleeve 1 is communicated with a delivery pipe 13, and the puncture sleeve 1 is provided with an output port 12 for discharging cold gas medium at one end;
[0044] One side of the sliding groove 11 is also communicated with a collection mechanism for collecting external tissues based on the pushing of the needle 2, the single needle 4 and the ice knife 5. The collection mechanism includes a mounting piece 30 which is slidingly fitted with the puncture sleeve 1, a deformable stretching piece 3 which is slidingly fitted at the center of the mounting piece 30, and a plurality of scraping teeth which are fixedly connected on both sides of the stretching piece 3. One end of the stretching piece 3 is hinged to one end of the mounting piece 30 close to the output port 12, the stretching piece 3 is slidingly fitted with the mounting piece 30, a rubber block 31 is fixedly connected to one side of the stretching piece 3 away from the puncture sleeve 1, the top of the rubber block 31 is a vertical surface, and the bottom of the rubber block 31 is an arc surface.
[0045] One end of the single needle 4, the ice knife 5 and the needle 2 close to the output port 12 is provided with a matching groove 6, the ice knife 5 is communicated with an exhaust pipe 51, and one end of the exhaust pipe 51 is located on one side of the ice knife 5 close to the output port 12.
[0046] In this embodiment, a spring is fixedly connected between one end of the stretching piece 3 away from the output port 12 and the mounting piece 30, one end of the mounting piece 30 close to the output port 12 is fixedly connected with a shielding piece 32, the shielding piece 32 is located between the stretching piece 3 and the center of the puncture sleeve 1, and a collection groove is opened on one side of the shielding piece 32 close to the stretching piece 3; in another embodiment, a rotating shaft is rotatably connected between the rubber block 31 and the stretching piece 3 to enhance the rotating effect of the rubber block 31 and facilitate the rubber block 31 to no longer abut against the single needle 4 or the ice knife 5.
[0047] One end of the puncture sleeve 1 close to the output port 12 is provided with an isolation layer; a bimetallic strip 62 is provided between the rubber block 31 and the stretching piece 3, one end of the bimetallic strip 62 is located in the rubber block 31, the other end of the bimetallic strip 62 is located in the stretching piece 3, and the thermal expansion coefficient of one end of the bimetallic strip 62 close to the output port 12 is greater than that of the other end of the bimetallic strip 62 away from the output port 12.
[0048] The side of the single needle 4 close to the matching groove 6 is fixedly connected with an electromagnet 61, and the electromagnet 61 works based on the generation of high-voltage electric pulses; when the electromagnet 61 works, the electromagnet 61 abuts against the rubber block 31.
[0049] The specific implementation process is as follows:
[0050] In the CT ultrasound image display process, irreversible electroporation and cryoablation are guided to ensure the positioning accuracy in the process of treating lung ground glass nodules. The puncture sleeve 1 provides an operation channel, and the single needle 4 and the ice knife 5 are transported as needed to reduce the damage to the surrounding tissues in the process of treating lung ground glass nodules, and facilitate repeated sampling to provide a basis for judging the treatment results.
[0051] As shown in Figure 7 During the movement of the single needle 4, the ice knife 5 and the needle 2 inside the puncture sleeve 1, the needle 2 is used to puncture the tissues in the body to facilitate the installation of the puncture sleeve 1, and the ice knife 5 and the single needle 4 are replaced to adapt to the needs of different surgical procedures. The cooperation of the matching groove 6 and the rubber block 31 is used during the installation of the single needle 4, the ice knife 5 and the needle 2. The matching groove 6 is in contact with the vertical surface to push the stretching sheet 3 to be compressed, so that the stretching sheet 3 extends out of the puncture sleeve 1, and the stretching sheet 3 is in contact with the external tissues. It is convenient to obtain the external tissues according to the movement and removal of the single needle 4, the ice knife 5 and the needle 2 to determine the corresponding tissue cells before treatment, after irreversible electroporation treatment and after cryoablation treatment, and to confirm the surgical effect after treatment.
[0052] During the treatment, the delivery pipe 13 is used to maintain the temperature of the tissues collected by the collection mechanism to reduce the deformation of the treated tissues due to temperature changes and reduce the destructive effect on the original tissues, so as to provide a reference basis for the doctor to understand the tissues before and after treatment and facilitate the control of the parameters during the operation. Then the scraping teeth are used to scrape the surrounding tissues to facilitate the collection and processing of the surrounding tissues and improve the collection efficiency.
[0053] For the cryoablation process, the cold gas medium discharged by the ice knife 5 is used to cool the surrounding tissues to form ice crystals, and the bimetallic strip 62 is bent towards the output port 12 after being cooled. The matching groove 6 is no longer in contact with the rubber block 31, so that the stretched spring drives the stretching sheet 3 to contract, and the stretching sheet 3 is attached to the shielding sheet 32, so that the surrounding tissues are hidden in the collection groove, realizing the collection of the surrounding tissues and facilitating the collection of the tissue cells after cryoablation treatment.
[0054] When high-voltage electric pulses are generated in the process of bipolar energization on the single needle 4, the isolation layer is used to reduce the influence of the electromagnetic field in the process of the electromagnetic iron 61, to ensure the accurate resetting of the stretching sheet 3. At the same time, the electromagnetic iron 61 is started to work, so that the electromagnetic iron 61 can adsorb the magnetic metal of the bimetallic sheet 62 in the rubber block 31, for example, the commonly used active layer material with high thermal expansion coefficient such as copper, manganese-nickel-copper alloy, and the commonly used active layer material with low thermal expansion coefficient such as iron, nickel-iron alloy. The iron is a magnetic metal which can be adsorbed by the magnetic force generated by the electromagnetic iron 61, so that the bimetallic sheet 62 drives the rubber block 31 to slide in the sliding groove 11 to rotate, so that the rubber block 31 is no longer located in the sliding groove 11. The stretching spring is used to drive the stretching sheet 3 to shrink, so that the stretching sheet 3 is attached to the shielding sheet 32, which is convenient for the surrounding tissue to hide in the collection groove, realizes the collection of the surrounding tissue, and is convenient for collecting the tissue cells after the irreversible electroporation treatment, and guarantees the clearing effect of the lung ground glass nodule (combined with the lung ground glass nodule shown in Figure 7 and Figure 8 ).
[0055] Embodiment 2:
[0056] The difference between the embodiment 1 and the embodiment 2 is that the temperature sensor is fixedly connected to the side of the stretching sheet 3 away from the puncture cannula 1, and the temperature sensor is used to measure the temperature data of the surrounding tissue in real time, and send the temperature data to the CT display module.
[0057] The CT display module is electrically connected with the processing module, the processing module is used to record the temperature data in real time, and is used to input the current time corresponding to the operation process. The operation process includes the normal body temperature data in the process of the needle 2 puncture, the first reference data corresponding to the irreversible electroporation treatment process, and the second reference data corresponding to the cryoablation treatment process. The temperature data is compared with the temperature data corresponding to the operation process at the current time. If the current time is the process of the needle 2 puncture, the temperature data at the current time is marked as the normal body temperature data. If the current time is the irreversible electroporation treatment process, the temperature data is compared with the first reference data. If it is consistent, the continuous treatment display instruction is sent to the CT display module. If it is not consistent, the continuous stop display instruction is sent to the CT display module. If the current time is the cryoablation treatment process, the temperature data is compared with the second reference data. If the temperature data is greater than or equal to the second reference data, the ablation completion instruction is sent to the CT display module. If the temperature data is less than the second reference data, the unfreezing completion instruction is sent to the CT display module.
[0058] For example, the temperature data is compared and processed to display the patient's body temperature data so that the physician can determine whether the patient's body temperature is normal. During the irreversible electroporation treatment, the temperature data is compared with the first reference data to remind the physician to insert the puncture sleeve 1 and use the single needle 4 to pull back and press in to push the rubber block 31 to drive the stretching piece 3 to extend, and use the stretching piece 3 to collect the biopsy of the surrounding tissue to ensure the accuracy of the treatment results.
[0059] During the cryoablation treatment, the temperature data is compared with the second reference data to remind the physician whether the in-vivo tissue has completed the tissue re-warming ablation, provide a reference basis for repeating the cryoablation or guidance for completing the cryoablation, and facilitate the physician to perform subsequent operations.
[0060] Embodiment 3:
[0061] The difference between embodiment 2 and embodiment 3 is that the delivery pipe 13 in the puncture sleeve 1 is located around the mounting piece 30.
[0062] The specific implementation process is as follows: the temperature of the surrounding tissue is measured and displayed by the temperature sensor to regulate the temperature change of the liquid medium delivered in the delivery pipe 13, and the temperature is maintained to reduce the influence of temperature on the collected tissue during different treatments, and to provide a reference basis for the subsequent physician's diagnosis and treatment.
[0063] Embodiment 4:
[0064] The difference between embodiment 3 and embodiment 4 is that the puncture sleeve 1 is fixedly connected with a clamping block at one end close to the mounting piece 30, and the end of the matching groove 6 away from the stretching piece 3 is arc-shaped.
[0065] The specific implementation process is as follows: the position of the mounting piece 30 is limited by the clamping block to maintain the fixation of the stretching piece 3, so as to form unilateral retention during irreversible electroporation or cryoablation, facilitate the formation of contrast effect, and facilitate the physician to understand the tissue changes before and after operation.
[0066] Embodiment 5:
[0067] The difference between embodiment 4 and embodiment 5 is that the delivery pipe 13 is communicated with a plurality of electromagnetic valves at one side close to the puncture sleeve 1, the electromagnetic valves are electrically connected with the processing module, and the electromagnetic valves are uniformly arranged in the length direction of the mounting piece 30.
[0068] The specific implementation process is as follows: the processing module controls the opening and closing of the uniformly arranged electromagnetic valves, so that when the sample is taken out by driving the stretching sheet 3 through the mounting sheet 30, the cold and hot medium is alternately discharged through the conveying pipe 13 to kill the tissue that may be left in the puncture cannula 1, so as to reduce the pollution to the subsequent collected tissue and ensure the accuracy in the subsequent biopsy process.
[0069] Obviously, the above embodiments are only examples for clearly illustrating, but not limitation to the embodiments. Based on the above description, other different forms of changes or variations can be made by those skilled in the art. Here, all the embodiments need not and cannot be exhausted. The obvious changes or variations derived therefrom are still within the protection scope of the present application.
Claims
1. A lung tumor treatment device based on irreversible electroporation and cryoablation, comprising a single needle (4) for generating high-voltage electric pulses, an ice knife (5) for delivering a cold gas medium, and a CT display module for displaying CT images in real time, characterized in that, The puncture sleeve (1) is provided with a sliding groove (11), and a single needle (4) and an ice knife (5) are in clearance fit with the sliding groove (11); The needle (2) is detachably connected in the sliding groove (11), the puncture sleeve (1) is communicated with a conveying pipe (13), and the puncture sleeve (1) is provided with an outlet (12) for discharging cold gas medium at one end; The sliding groove (11) is further communicated with a collection mechanism for collecting external tissues, and the collection mechanism is used for collecting the external tissues based on the pushing of the needle (2), the single needle (4) and the ice knife (5); The collection mechanism comprises a mounting piece (30) in sliding fit with the puncture sleeve (1), a deformable stretching piece (3) in sliding fit at the center of the mounting piece (30), and a rubber block (31) fixedly connected to one side of the stretching piece (3) away from the puncture sleeve (1), wherein the top of the rubber block (31) is a vertical surface, and the bottom of the rubber block (31) is an arc surface; The single needle (4), the ice knife (5) and the needle (2) are all provided with a matching groove (6) at one end close to the outlet (12); A spring is fixedly connected between one end of the stretching piece (3) away from the outlet (12) and the mounting piece (30), one end of the mounting piece (30) close to the outlet (12) is fixedly connected with a shielding piece (32), the shielding piece (32) is located between the stretching piece (3) and the center of the puncture sleeve (1), and the side of the shielding piece (32) close to the stretching piece (3) is provided with a collection groove; A bimetallic strip (62) is arranged between the rubber block (31) and the stretching piece (3), one end of the bimetallic strip (62) is located in the rubber block (31), the other end of the bimetallic strip (62) is located in the stretching piece (3), and the thermal expansion coefficient of one end of the bimetallic strip (62) close to the outlet (12) is greater than that of the other end of the bimetallic strip (62) away from the outlet (12); The single needle (4) is fixedly connected with an electromagnet (61) on the side close to the matching groove (6), and the electromagnet (61) is used for working based on the generation of high-voltage electric pulse; When the electromagnet (61) works, the electromagnet (61) abuts against the rubber block (31).
2. The lung tumor treatment device based on irreversible electroporation and cryoablation of claim 1, wherein, A plurality of scraping teeth are fixedly connected to both sides of the stretching piece (3).
3. The lung tumor treatment device based on irreversible electroporation and cryoablation of claim 2, wherein, A temperature sensor is fixedly connected to the side of the stretching piece (3) away from the puncture sleeve (1), and the temperature sensor is used for measuring temperature data of surrounding tissues in real time and sending the temperature data to a CT display module. The CT display module is electrically connected with a processing module, the processing module is used for recording temperature data in real time, and is used for inputting a surgical procedure corresponding to a current time, the surgical procedure includes normal body temperature data in a needle (2) puncture process, first reference data corresponding to an irreversible electroporation treatment process and second reference data corresponding to a cryoablation treatment process, comparing the temperature data with temperature data corresponding to the surgical procedure of the current time, if the current time is the needle (2) puncture process, marking the temperature data of the current time as the normal body temperature data, if the current time is the irreversible electroporation treatment process, comparing the temperature data with the first reference data, if it is consistent, sending a continuous treatment display instruction to the CT display module, if it is not consistent, sending a continuous stop display instruction to the CT display module, if the current time is the cryoablation treatment process, comparing the temperature data with the second reference data, if the temperature data is greater than or equal to the second reference data, sending an ablation completion instruction to the CT display module, if the temperature data is less than the second reference data, sending an unfreezing completion instruction to the CT display module.
4. The lung tumor treatment device based on irreversible electroporation and cryoablation of claim 3, wherein, The delivery pipe (13) in the puncture sleeve (1) is located around the mounting piece (30).
5. The lung tumor treatment device based on irreversible electroporation and cryoablation of claim 4, wherein, The puncture sleeve (1) is fixedly connected with a clamping block at one end close to the mounting piece (30), and the end of the cooperating groove (6) away from the stretching piece (3) is arc-shaped.
6. The lung tumor treatment device based on irreversible electroporation and cryoablation of claim 5, wherein, The puncture sleeve (1) is provided with an isolation layer at one end close to the output port (12).
7. The device for lung tumor treatment based on irreversible electroporation and cryoablation according to claim 6, characterized in that, The delivery pipe (13) is communicated with a plurality of electromagnetic valves at one side close to the puncture sleeve (1), the electromagnetic valves are electrically connected with the processing module, and the electromagnetic valves are evenly arranged in the length direction of the mounting piece (30).
Citation Information
Patent Citations
Equipment for minimally invasive composite treatment and multifunctional surgical needle group thereof
CN209360881U
Puncture sampler for medical oncology
CN211243471U