Whitening composition suitable for sensitive skin and application thereof

Abstract

The invention discloses a whitening composition suitable for sensitive skin and application of the whitening composition, and particularly belongs to the field of dressing preparations. The composition comprises a palmaria palmata extract, a myrothamnus flabellifolia leaf / stem extract, a grape seed extract and nicotinamide. The whitening composition suitable for sensitive skin provided by the invention can effectively inhibit synthesis of tyrosinase, and has an excellent whitening effect; the essence containing the whitening composition suitable for sensitive skin provided by the invention has an excellent whitening effect.

Description

Technical Field

[0001] The present invention belongs to the field of cosmetics, and in particular relates to a whitening composition suitable for sensitive skin and an application thereof. Background Art

[0002] In recent years, the market for whitening cosmetics has continued to expand, driven by consumers' growing demand for skin health and aesthetics. However, those with sensitive skin face significant challenges in their pursuit of whitening results. Traditional whitening ingredients (such as high-concentration vitamin C derivatives and fruit acids) can easily cause redness, stinging, dryness, and even allergic reactions. Their potent whitening mechanisms often come at the expense of skin barrier function, further exacerbating sensitivity. Furthermore, single whitening ingredients often have a narrow pathway of action, making it difficult to achieve a comprehensive, "source-blocking" and metabolically accelerated, regulation of melanin production. This results in limited whitening effectiveness and a tendency for darkening to reappear.

[0003] Current research and development of whitening compounds often focuses on optimizing a single target (such as simply inhibiting tyrosinase activity or promoting exfoliation), neglecting systematic adaptation to the physiological characteristics of sensitive skin. For example, while niacinamide effectively blocks the transport of melanosomes into the stratum corneum, its use in high concentrations can easily induce skin intolerance. The strong irritation of plant extracts (such as arbutin and kojic acid) can exacerbate inflammatory responses in sensitive skin. More critically, most formulations fail to balance the synergistic effects of barrier repair and moisturizing in sensitive skin, resulting in difficulties in the stable penetration and long-lasting effects of whitening active ingredients. This can even lead to secondary hyperpigmentation due to disrupted skin metabolic environment.

[0004] In response to the above technical bottlenecks, there is an urgent need to build a composite whitening system with high-efficiency whitening and moisturizing effects to provide a safe, gentle and long-lasting whitening solution for people with sensitive skin. Summary of the Invention

[0005] In view of the shortcomings of the prior art, the present invention aims to provide a composition with whitening effect, in which the components in the composition synergize with each other and have significant whitening effect.

[0006] In order to achieve the above object, the present invention discloses the following technical solutions: In a first aspect, the present invention provides a whitening composition suitable for sensitive skin, the composition comprising the following components: palmatum extract, mirabilis leaf / stem extract, grape seed extract, and niacinamide; The mass ratio of palm tree extract, myrrh leaf / stem extract, grape seed extract and niacinamide is 1: (1-3): (1.5-2.5): (0.2-0.6).

[0007] Preferably, the mass ratio of the palm tree extract, the myrtlesia leaf / stem extract, the grape seed extract, and niacinamide is 1:(1-2):(2-2.5):(0.4-0.6).

[0008] Further preferably, the mass ratio of the Palmatum palmatum extract, the Myrtillus niger leaf / stem extract, the grape seed extract, and niacinamide is 1:2:2:0.4.

[0009] Further preferably, the palm tree extract is a water extract using palm-shaped dulse as the extraction raw material; the myrrh leaf / stem extract is an alcohol extract using myrrh leaf / stem as the extraction raw material; and the grape seed extract is an alcohol extract using grape seeds as the extraction raw material.

[0010] In a second aspect, the present invention provides use of the whitening composition suitable for sensitive skin described in the first aspect in the preparation of a skin care product.

[0011] Preferably, the skin care product dosage form is any one of lotion, cream, essence, eye cream, lotion, and facial mask.

[0012] In a third aspect, the present invention provides an essence with whitening effect suitable for sensitive skin, comprising the whitening composition suitable for sensitive skin described in the first aspect, wherein the amount of the whitening composition suitable for sensitive skin added to the essence is 1-5wt%.

[0013] Preferably, the essence further comprises a moisturizer, a preservative, an emulsifier, and a solvent.

[0014] More preferably, the moisturizing agent is at least one of glycerin, butylene glycol, propylene glycol, 1,2-pentanediol, and dipropylene glycol.

[0015] More preferably, the preservative is phenoxyethanol and / or methylparaben.

[0016] Further preferably, the emulsifier is at least one of PPG-26-butanediol polyether-26, PEG / PPG-17 / 6 copolymer, and glycerol polyether-26.

[0017] More preferably, the solvent is deionized water.

[0018] Beneficial effects of the present invention: The present invention innovatively combines Palmaria palmata extract, Myrothamnus leaf / stem extract, grape seed extract, and niacinamide to produce a whitening composition suitable for sensitive skin. Palmaria palmata extract, also known as palm-shaped dulse extract, is rich in essential amino acids and polysaccharides, exhibiting antioxidant properties, enhancing skin repair ability, inhibiting tyrosinase catalytic reactions, and promoting collagen synthesis. Myrothamnus flabellifolia leaf / stem extract contains ceramides, squalene, proanthocyanidins, polyphenols, and flavonoids, exhibiting excellent antioxidant properties, strengthening the skin barrier, and enhancing stratum corneum metabolism. Grape seed extract is rich in active substances such as proanthocyanidins, polyphenols, and unsaturated fatty acids, exhibiting tyrosinase inhibition, antioxidant properties, and sebum regulation. Niacinamide can inhibit the transport of melanin into the stratum corneum, reduce pigmentation, promote epidermal cell renewal, and accelerate the shedding of melanin-containing keratin. The four together can achieve full regulation of melanin production, transport and metabolism, and have excellent whitening effects. DETAILED DESCRIPTION

[0019] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0020] The technical solutions of the present invention are further described in detail below with reference to specific embodiments. It should be understood that the following embodiments are merely used to explain the present invention and are not intended to limit the present invention.

[0021] In the present invention: raw material Purchased from Product Name Extract type Palmatum Extract Guangzhou Baoyi Biotechnology Co., Ltd. Palmatum Extract Water extraction Mirifica Leaf / Stem Extract Guangzhou Aoxue Chemical Co., Ltd. Mirifica Leaf / Stem Extract alcohol extract grape seed extract Guangzhou Lingyu Trading Co., Ltd. Composite whitening agent alcohol extract Niacinamide Guangzhou Baihaobo Co., Ltd. Niacinamide - Other raw materials Commercially available - - Preparation of whitening composition suitable for sensitive skin The whitening compositions suitable for sensitive skin are prepared by compounding the following components in parts by mass: Composition 1: 1 part of Palmyra palmatum extract, 2 parts of Myrtillus niger leaf / stem extract, 2 parts of Grape seed extract, and 0.4 parts of Niacinamide.

[0022] Composition 2: 1 part of Palmatum chinense extract, 1 part of Mironia suffruticosa leaf / stem extract, 2.5 parts of Grape seed extract, and 0.2 parts of Niacinamide.

[0023] Composition 3: 1 part of Palmatum chinense extract, 3 parts of Mironia suffruticosa leaf / stem extract, 1.5 parts of Grape seed extract, and 0.6 parts of Niacinamide.

[0024] Composition ①: Different from composition 1, niacinamide was not added, and the missing parts by mass were made up with deionized water.

[0025] Composition ②: Different from composition 1, no Myrtillus chinensis leaf / stem extract, Palmatum chinense extract, or grape seed extract was added, and the missing parts by mass were made up with deionized water.

[0026] Composition ③: Different from composition 1, no mirabilis leaf / stem extract and grape seed extract were added, and the missing parts by weight were made up with deionized water.

[0027] Composition ④: Different from composition 1, no palm leaf extract and grape seed extract were added, and the missing parts by mass were made up with deionized water.

[0028] Composition ⑤: Different from composition 1, no palm leaf extract and iris leaf / stem extract were added, and the missing parts by weight were made up with deionized water.

[0029] Preparation of whitening serum for sensitive skin: The components of the essence are shown in Table 1. The preparation method of the essences 1-5 comprises the following steps: S1: Heat deionized water to 60°C, add palm leaf extract, mirabilis leaf / stem extract, and grape seed extract, and stir well to obtain a mixed solution; S2: Cool the mixed solution to 50°C, add a moisturizer, a preservative, and an emulsifier, and stir evenly to obtain a mixed solution A; S3: Cool the mixed solution A to 40°C, add niacinamide, and stir evenly to obtain a whitening essence suitable for sensitive skin; If a component in a certain step in the above steps does not exist, deionized water is used to replace the component for addition.

[0030] Table 1 Composition of whitening serums suitable for sensitive skin

[0031] Note: “-” means the item does not exist.

[0032] Performance test of whitening composition suitable for sensitive skin: Test samples: Essence 1-5, Essence ①-⑤, blank.

[0033] Test area: Whitening and moisturizing effect test area: whole face Irritation test test area: 2 × 2 cm area on the inner side of the forearm of the left or right arm.

[0034] Whitening and Moisturizing Efficacy Test Method: Volunteers aged 30-50 years with whitening needs and positive lactic acid stimulation were selected as subjects. They were evenly divided into 11 groups of 10 participants each, with each group corresponding to one test sample. During the 28-day trial, volunteers used 3 mL of the product once daily.

[0035] Data Collection: Whitening efficacy data collection: A skin red-melanin tester was used to assess changes in melanin content in the test area of the subjects before and after application of the test sample. The measured value is proportional to the melanin content. Before application of the test sample, the melanin content of the test area was measured, recorded as M0. On the 29th day after the experiment, the melanin content of the test area was measured, recorded as M1. The melanin content change rate, X, = (M0 - M1) / M0 × 100%. The results are shown in Table 2.

[0036] Moisturizing data collection: On the first day of the test, before applying the test sample, the skin moisture content of the test area was measured using a skin moisture tester and recorded as N0. The skin moisture content in the test area was measured again 120 minutes after applying the test sample and recorded as N1. The 2h moisturizing rate = (N1-N0) / N0×100%. The results are shown in Table 2.

[0037] The melanin content or water content mentioned in the data collection are the average values within the group.

[0038] Two days before the whitening and moisturizing performance tests, the irritation of the essence was evaluated. The irritation evaluation criteria are as follows: Irritation evaluation method: Volunteers aged 30-50 years with whitening needs and positive lactic acid irritation were selected as subjects and evenly divided into 11 groups, with 10 people in each group. Each group corresponded to one test sample. 0.5 mL of the test sample was applied to the test area of each volunteer. After the volunteer used the test sample for 30 minutes, the volunteer's skin condition was observed. If the result was negative, the observation was continued for 24 hours. If the evaluation standard was above level 2, the experiment was terminated. The results are shown in Table 2.

[0039] Judging criteria: Grade 0: negative reaction; Grade 1: Suspicious reaction, only slight erythema; Grade 2: weak positive reaction, erythema, infiltration, edema, and papules may be present; Grade 3: Strong positive reaction, with erythema, infiltration, edema, papules, and the reaction may extend beyond the test area; Grade 4: Very strong positive reaction, obvious erythema, severe infiltration, edema, confluent blister, and reaction beyond the test area.

[0040] Table 2 Performance test results Group Change rate X / % Irritation (level) 2h moisturizing rate / % Essence 1 24.36 0 69.52 Essence 2 10.28 0 46.37 Essence 3 28.72 0 72.33 Essence 4 23.68 0 63.14 Essence 5 24.15 0 63.58 Essence ① 11.64 0 49.55 Essence ② 6.53 0 38.77 Essence ③ 8.72 0 43.36 Essence ④ 9.21 0 45.57 Essence ⑤ 11.67 0 45.14 blank -0.07 0 29.63 Result analysis: According to the test results in Table 2, the essence provided by the present invention has a whitening effect. Comparing the results of essences 1, 4-5, it can be seen that the dosage ratio of the various raw materials in the whitening composition suitable for sensitive skin has a certain effect on the whitening and moisturizing effects.

[0041] Comparing the results of Essence 1 with Essences ①-②, it can be seen that the use of palm leaf extract, myrrh leaf / stem extract, grape seed extract and niacinamide together can enhance the whitening and moisturizing effects of the composition, and there is a synergistic effect between the raw materials in the composition.

[0042] Comparing the results of Essence ① with Essence ②-⑤, it can be seen that, after removing the influence of niacinamide, the combination of palm leaf extract, mirabilis leaf / stem extract and grape seed extract can also enhance the whitening and moisturizing effects of the composition. The three together also have a synergistic effect.

[0043] According to the results of the irritation test, the essence provided by the present invention is safe and non-irritating, and is suitable for people with sensitive skin.

[0044] Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or substitute equivalents for some of the technical features. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. A whitening composition suitable for sensitive skin, characterized in that: Including the following ingredients: Palmatum Extract, Myrtillus Leaf / Stem Extract, Grape Seed Extract, Niacinamide.

2. The whitening composition according to claim 1, characterized in that The mass ratio of the palm tree extract, the myrtlesia leaf / stem extract, the grape seed extract and the niacinamide in the whitening composition is 1:(1-3):(1.5-2.5):(0.2-0.6).

3. The whitening composition according to claim 1, characterized in that The mass ratio of the palm tree extract, the myrtlesia leaf / stem extract, the grape seed extract and the niacinamide in the whitening composition is 1:(1-2):(2-2.5):(0.4-0.6).

4. The whitening composition according to claim 1, characterized in that The mass ratio of the palm tree extract, the myrtlesia leaf / stem extract, the grape seed extract and the niacinamide in the whitening composition is 1:2:2:0.

4.

5. Use of the whitening composition according to any one of claims 1 to 4 in the preparation of skin care products.

6. The use according to claim 5, characterized in that The skin care product dosage form is any one of lotion, cream, essence, eye cream, lotion, and facial mask.

7. A whitening essence suitable for sensitive skin, characterized in that: The essence contains the following components in percentage by weight: 1-5% of the whitening composition according to any one of claims 1-4; Moisturizer 1-3%; Preservatives 0.1-0.5%; Emulsifier 0.1-0.5%; Make up to 100% with deionized water.

8. The essence according to claim 7, characterized in that The moisturizing agent is at least one of glycerin, butylene glycol, propylene glycol, 1,2-pentanediol, and dipropylene glycol; and the preservative is phenoxyethanol and / or methylparaben.

9. The essence according to claim 7, characterized in that The emulsifier is at least one of PPG-26-butanol polyether-26, PEG / PPG-17 / 6 copolymer, and glycerol polyether-26.

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