Lotus leaf and cassia seed medicinal and edible composition for reducing blood fat and preparation method of lotus leaf and cassia seed medicinal and edible composition

Abstract

The invention discloses a lotus leaf and cassia seed medicinal and edible composition for reducing blood fat and a preparation method thereof, and belongs to the technical field of health food. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 2-5 parts of lotus leaves, 2-5 parts of cassia seeds, 2-8 parts of cinnamon, 2-8 parts of astragalus membranaceus, 2-5 parts of liquorice and 10-15 parts of poria cocos. The invention provides a safe and effective medicinal and edible composition of lotus leaf and cassia seed and a preparation method of a product. The medicinal and edible composition has remarkable health-care effects in the aspects of diseases such as lowering lipid, regulating blood lipid metabolism and the like.

Description

Technical Field

[0001] The present invention relates to the technical field of health-care foods, in particular to a blood lipid-lowering lotus leaf and cassia seed medicinal and edible composition and a preparation method thereof. Background Art

[0002] In 2022, over one billion people worldwide will be obese, the vast majority of whom are adults. The 2024 World Obesity Report indicates that by 2025, overweight or obese adults will reach 46% of the global adult population. This will lead to an annual increase in the number of people suffering from complications such as high blood lipids, high blood pressure, high blood sugar, and heart disease, posing a serious threat to human health. The World Health Organization (WHO) and other organizations have called on governments to adopt comprehensive measures to address obesity, including improving dietary habits, increasing physical activity, strengthening health education, and providing obesity treatment services. Ingredients with both medicinal and edible properties are widely used in various weight loss supplements and functional foods. For example, lotus leaves, cassia seeds, and hawthorn are often used in tea substitutes, capsules, and tablets to meet consumer demand for healthy and natural weight loss products. Guided by Traditional Chinese Medicine (TCM), edible and medicinal herbs can be combined with other ingredients to create medicated diets, which can be used as part of daily diet to achieve weight loss. This approach not only maximizes the pharmacological effects of TCM, but also ensures a balanced taste and nutritional profile. The effectiveness of traditional Chinese medicine formulas is widely recognized and supported by scientific research. However, some of these herbs contain ingredients with significant toxic side effects, which are prohibited from use in food. With the modern society's pursuit of a healthy lifestyle, ingredients that combine medicinal and edible properties are widely used in the production of both regular and functional foods. These ingredients aim to improve health by adjusting dietary intake, providing an effective non-drug intervention for chronic sub-health conditions.

[0003] At present, there is a lack of preparation methods for medicinal and edible compositions that can be directly used in functional foods, which limits the research on the combination of medicinal and edible raw materials with nutrition, and makes it impossible to provide consumers with personalized and precise functional fat-reducing products. Summary of the Invention

[0004] The purpose of the present invention is to provide a lotus leaf and cassia seed medicinal and edible composition for lowering blood lipids and a preparation method thereof, so as to solve the problems existing in the above-mentioned prior art.

[0005] To achieve the above object, the present invention provides the following solutions:

[0006] One of the technical solutions of the present invention is a lotus leaf and cassia seed medicinal and edible composition for lowering blood lipids, which comprises the following raw materials in parts by weight: 2-5 parts of lotus leaf, 2-5 parts of cassia seed, 2-8 parts of cinnamon bark, 2-8 parts of astragalus, 2-5 parts of licorice and 10-15 parts of poria.

[0007] The second technical solution of the present invention is a rice porridge containing a medicinal and edible composition of lotus leaves and cassia seeds, which includes the following raw materials, by weight: 20-40 parts of polished rice, 20-40 parts of oats, 10-30 parts of soybeans, 5-15 parts of whey protein powder, 5-10 parts of freeze-dried powder of the medicinal and edible composition of lotus leaves and cassia seeds, and 2-8 parts of medium-chain fatty acids.

[0008] The third technical solution of the present invention is a method for preparing the lotus leaf and cassia seed medicinal and edible composition, comprising the following steps:

[0009] (1) Crush lotus leaves, cassia seeds, cinnamon bark, astragalus root, licorice root, and poria cocos and soak them;

[0010] (2) First, boil the liquid with high heat, then simmer with low heat, and filter to obtain the liquid;

[0011] (3) The liquid is subjected to rotary evaporation, concentration, and freeze-drying to obtain freeze-dried powder of the lotus leaf and cassia seed medicinal and edible composition.

[0012] The fourth technical solution of the present invention is a method for preparing rice porridge, comprising the following steps:

[0013] Polished rice, oats and soybeans are crushed and then soaked, cooked for gelatinization, pulped, cooked and crushed; and then mixed with freeze-dried powder of a medicinal and edible composition of lotus leaf and cassia seed, whey protein powder and medium-chain fatty acids to obtain the medicinal and edible composition of lotus leaf and cassia seed.

[0014] Based on the above technical solution, the present invention has the following technical effects:

[0015] The present invention provides a safe and effective lotus leaf and cassia seed medicinal and edible composition and a preparation method of the product. The medicinal and edible composition exhibits significant health-care effects in reducing blood lipids, regulating blood lipid metabolism and other diseases. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0017] Figure 1 This is a graph showing the effect of the composition of the present invention on the body weight changes of mice fed a high-fat diet.

[0018] Figure 2 The present invention shows the effect of the composition on the liver quality of mice fed a high-fat diet.

[0019] Figure 3 The present invention shows the effect of the composition of the present invention on the epididymal fat mass of mice fed a high-fat diet.

[0020] Figure 4 The present invention shows the effect of the composition of the present invention on glucose homeostasis in mice fed a high-fat diet.

[0021] Figure 5 The present invention shows the effect of the composition on the blood lipid level of mice fed a high-fat diet. DETAILED DESCRIPTION

[0022] Various exemplary embodiments of the present invention will now be described in detail. This detailed description should not be considered as limiting the present invention, but rather as a more detailed description of certain aspects, features, and embodiments of the present invention.

[0023] It should be understood that the terms described herein are intended only to describe particular embodiments and are not intended to limit the present invention. In addition, for numerical ranges herein, it should be understood that each intermediate value between the upper and lower limits of the range is also specifically disclosed. Each smaller range between any intermediate value within a stated value or stated range and any other stated value or intermediate value within the stated range is also encompassed by the present invention. The upper and lower limits of these smaller ranges may be independently included or excluded within the scope.

[0024] Unless otherwise indicated, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art. Although only preferred methods and materials are described herein, any methods and materials similar or equivalent to those described herein may also be used in the practice or testing of the present invention. All documents mentioned in this specification are incorporated by reference to disclose and describe the methods and / or materials associated with the documents. In the event of any conflict with any incorporated document, the contents of this specification shall prevail.

[0025] It will be apparent to those skilled in the art that various modifications and variations may be made to the specific embodiments of the present invention without departing from the scope or spirit of the invention. Other embodiments will be apparent to those skilled in the art from the present invention. The present description and examples are intended to be illustrative only.

[0026] The words “include,” “including,” “have,” “contain,” etc. used in this document are open-ended terms, meaning including but not limited to.

[0027] Unless otherwise specified, the technical solutions described in the present invention are all conventional solutions in the field, and the reagents or raw materials used, unless otherwise specified, are purchased from commercial channels or have been disclosed.

[0028] The embodiment of the present invention provides a lotus leaf and cassia seed medicinal and edible composition for lowering blood lipids, which comprises the following raw materials in parts by weight: 2-5 parts of lotus leaves, 2-5 parts of cassia seeds, 2-8 parts of cinnamon, 2-8 parts of astragalus, 2-5 parts of licorice and 10-15 parts of poria.

[0029] In some specific embodiments, the following raw materials are included, by weight: 3 parts of lotus leaves, 3 parts of cassia seeds, 6 parts of cinnamon bark, 6 parts of astragalus, 4 parts of licorice and 12 parts of poria.

[0030] An embodiment of the present invention also provides a rice porridge containing a lotus leaf and cassia seed medicinal and edible composition, which includes the following raw materials, in parts by weight: 20-40 parts of japonica rice, 20-40 parts of oats, 10-30 parts of soybeans, 5-15 parts of whey protein powder, 5-10 parts of freeze-dried powder of the lotus leaf and cassia seed medicinal and edible composition, and 2-8 parts of medium-chain fatty acids.

[0031] In some specific embodiments, the following raw materials are included, by weight: 31 parts of polished rice, 31 parts of oats, 15 parts of soybeans, 10 parts of whey protein powder, 8 parts of freeze-dried powder of lotus leaf and cassia seed medicinal and edible composition, and 5 parts of medium-chain fatty acids.

[0032] The present invention also provides a method for preparing the lotus leaf and cassia seed medicinal and edible composition, comprising the following steps:

[0033] (1) Crush lotus leaves, cassia seeds, cinnamon bark, astragalus root, licorice root, and poria cocos and soak them;

[0034] (2) First, boil the liquid with high heat, then simmer with low heat, and filter to obtain the liquid;

[0035] (3) The liquid is subjected to rotary evaporation, concentration, and freeze-drying to obtain freeze-dried powder of the lotus leaf and cassia seed medicinal and edible composition.

[0036] In some specific embodiments, in step (1), the pulverization method is: passing through a 60-mesh sieve after pulverization; and the soaking time is 30 minutes.

[0037] In some specific embodiments, in step (2), the "slow fire" decocting time is 30-60 minutes; the filtering method is: filtering through 200 mesh gauze.

[0038] The present invention also provides a method for preparing the rice porridge, comprising the following steps:

[0039] Polished rice, oats and soybeans are crushed and then soaked, cooked for gelatinization, pulped, cooked and crushed; and then mixed with freeze-dried powder of a medicinal and edible composition of lotus leaf and cassia seed, whey protein powder and medium-chain fatty acids to obtain the medicinal and edible composition of lotus leaf and cassia seed.

[0040] In some specific embodiments, the pulverizing method is: pulverizing and then passing through a 200-mesh sieve.

[0041] This invention aims to improve the safety of traditional Chinese medicine formulas while maintaining their effectiveness by replacing ingredients with ingredients derived from both food and medicine, thereby creating a new composition formula that can be used in functional foods. With the modern society's pursuit of a healthy lifestyle, ingredients derived from both food and medicine are widely used in the production of both conventional and functional foods. This invention aims to improve health by adjusting dietary intake, providing an effective non-drug intervention for sub-healthy chronic diseases.

[0042] The whey protein powder used in the embodiments of the present invention was purchased from Nestle, and the medium-chain fatty acids were purchased from Shaanxi Cuiyajia Biotechnology Co., Ltd.

[0043] Example 1

[0044] A lotus leaf and cassia seed medicinal and edible composition comprises the following ingredients in parts by weight: 3 parts of lotus leaf, 3 parts of cassia seed, 6 parts of cinnamon bark, 6 parts of astragalus root, 4 parts of liquorice and 12 parts of poria.

[0045] The preparation method thereof comprises the following steps:

[0046] Step 1: Wash, dry and crush lotus leaves, cassia seeds, cinnamon bark, astragalus root, licorice root and poria cocos;

[0047] Step 2: Pass the medicinal and edible powder obtained from each material in step 1 through a 60-mesh sieve;

[0048] Step 3: Mix the materials thoroughly;

[0049] Step 4: Place the mixed powder of medicinal and edible properties prepared in step 3 into a Chinese medicine casserole, mix thoroughly with deionized water, and soak for 30 minutes;

[0050] Step 5: First, use the "high heat" function of the Chinese medicine casserole to boil the liquid;

[0051] Step 6: Use the "simmer" function of the Chinese medicine casserole to keep the liquid at a slight boil and simmer for 30-60 minutes;

[0052] Step 7: After frying, filter the liquid with 200 mesh gauze;

[0053] Step 8: Rotary evaporation, concentration and freeze-drying of the liquid material to obtain the lotus leaf and cassia seed medicinal and edible composition.

[0054] The freeze-dried powder of the lotus leaf and cassia seed medicinal and edible composition involved in this embodiment was used for subsequent in vivo animal experiment verification.

[0055] Example 2

[0056] In parts by weight, the raw materials of rice porridge include: 31 parts of polished round-grained rice, 31 parts of oats, 15 parts of soybeans, 10 parts of whey protein powder, 8 parts of freeze-dried powder of lotus leaf and cassia seed medicinal and edible composition, and 5 parts of medium-chain fatty acids.

[0057] A rice porridge containing lotus leaf and cassia seed medicinal and edible components is prepared by the following method:

[0058] Step 1: Select, wash, and dry the raw materials of polished rice, oats, and soybeans for later use;

[0059] Step 2: Crush the polished rice, oats and soybeans and soak them;

[0060] Step 3: Cook the compound from step 2 until it is gelatinized;

[0061] Step 4: Beating the gelatinized compound;

[0062] Step 5: Spread the rice paste obtained in step 4 on a baking tray and let it cook;

[0063] Step 6: Grind the cooked rice paste and pass it through a 200-mesh sieve for later use;

[0064] Step 7: Weigh the freeze-dried powder of the lotus leaf and cassia seed medicinal and edible composition, whey protein powder, and medium-chain fatty acids in proportion, mix them with rice flour, sieve, and package to obtain the finished product.

[0065] Example 3

[0066] The experimental methods and experimental results of the efficacy of the lotus leaf and cassia seed medicinal and edible composition in alleviating fat loss in mice induced by a high-fat diet are as follows:

[0067] 1. Experimental Methods

[0068] 1 Experimental animals and materials

[0069] SPF-grade 6-week-old male C57BL / 6J mice, weighing 20 ± 2 g, were fed with daily basal maintenance feed purchased from Jiangsu Jicui Yaokang Biotechnology Co., Ltd.; 60% high-fat feed D124492 was purchased from Research Diets, USA; blood glucose test strips were purchased from Roche, Germany; triglycerides (TC), total cholesterol (TG), low-density lipoprotein (LDL-C), and high-density lipoprotein (HDL-C) were purchased from Nanjing Jiancheng Bioengineering Institute.

[0070] 2 High-fat diet-induced obesity in mice and intervention

[0071] After one week of rest, the mice were randomly divided into three groups, 6 mice in each group, namely the control group (CON group, fed with daily basic maintenance feed), the model group (HFD group, fed with 60% high-fat feed D124492), and the lotus leaf and cassia seed combination group (JH group, fed with 60% high-fat feed D124492).

[0072] After 8 weeks of feeding, the CON and HFD groups were gavaged with normal saline (8 g / kg), and the JH group was gavaged with 8 g / kg of the lotus leaf and cassia seed medicinal and edible composition solution, once a day.

[0073] 3 Physiological index measurement

[0074] Body weight monitoring: The body weight of mice in each group was recorded regularly after administration;

[0075] Determination of organ weight index: At the end of the experiment, the liver and epididymal fat were weighed;

[0076] Glucose tolerance test: After the animals were fasted for 6 hours, the basal blood glucose was measured at 0 min and then 1.5 g / kg glucose was gavaged. Blood was collected from the tail vein of the mice and the blood glucose was measured at 30, 60, 90 and 120 min after glucose gavage using a Roche blood glucose meter to draw the blood glucose-time curve.

[0077] Blood lipid determination: After the administration, the animals were fasted for 12 h, blood was collected from the orbital cavity, and the blood was kept at room temperature for 2 h. The serum was separated by centrifugation (3000 rpm, 4°C, 15 min), and the serum total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels were determined according to the kit instructions.

[0078] 2. Experimental Results

[0079] Effects of the composition of the present invention on body weight, organ mass, oral glucose tolerance and blood lipid content of mice fed a high-fat diet Figure 1-5 shown.

[0080] The weight change trend of mice fed a high-fat diet treated with the composition of the present invention is shown in the figure below. Figure 1 As shown. Figure 1 It can be seen that after 8 weeks of high-fat diet feeding, the weight gain level of the HFD group was significantly higher than that of the CON group (p<0.05). After administration of the medicine-food composition of the present invention, the weight gain rate slowed down, slightly lower than that of the HFD group, and significantly higher than that of the control group.

[0081] The results of the effect of the composition of the present invention on the liver quality of mice fed a high-fat diet are as follows: Figure 2 As shown. Figure 2It can be seen that after 8 weeks of high-fat diet feeding, the liver weight of the HFD group was significantly higher than that of the CON group (p<0.05). After administration of the medicine-food composition of the present invention, the liver weight of the JH group was significantly reduced compared to the HFD group and slightly higher than that of the CON group.

[0082] The results of the effect of the composition of the present invention on the epididymal fat mass of mice fed a high-fat diet are as follows: Figure 3 As shown. Figure 3 It can be seen that after 8 weeks of high-fat diet feeding, the epididymal fat mass of the HFD group was significantly higher than that of the CON group (p<0.05). After administration of the medicine-food composition of the present invention, the epididymal fat mass of the JH group was significantly reduced compared to the HFD group and was significantly higher than that of the CON group.

[0083] The results of the effects of the composition of the present invention on glucose homeostasis in mice fed a high-fat diet are as follows: Figure 4 As shown. Figure 4 It can be seen that after 8 weeks of high-fat diet feeding, the blood glucose level of the HFD group was significantly higher than that of the CON group (p<0.05). After administration of the medicine-food composition of the present invention, the blood glucose index of the JH group was significantly lower than that of the HFD group.

[0084] The results of the effects of the composition of the present invention on the blood lipid levels of mice fed a high-fat diet are as follows: Figure 5 As shown. Figure 5 It can be seen that after 8 weeks of high-fat diet feeding, the TC, TG, and LDL-C levels in the HFD group were significantly higher than those in the CON group (p < 0.05), and the HDL-C level showed a downward trend. After administration of the medicine-food composition of the present invention, the TC, TG, and LDL-C levels in the JH group were significantly lower than those in the HFD group, and the HDL-C level showed an upward trend.

[0085] Obviously, the above embodiments of the present invention are merely examples for the purpose of clearly illustrating the present invention and are not intended to limit the implementation methods of the present invention. A person skilled in the art will be able to make other variations or modifications based on the above description. It is not necessary and impossible to enumerate all implementation methods here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the claims of the present invention.

Claims

1. A lotus leaf and cassia seed medicinal and edible composition for lowering blood lipids, characterized in that: The preparation comprises the following raw materials in parts by weight: 2-5 parts of lotus leaves, 2-5 parts of cassia seeds, 2-8 parts of cinnamon bark, 2-8 parts of astragalus root, 2-5 parts of liquorice and 10-15 parts of poria cocos.

2. The medicinal and edible composition of lotus leaf and cassia seed according to claim 1, characterized in that: The preparation comprises the following raw materials in parts by weight: 3 parts of lotus leaves, 3 parts of cassia seeds, 6 parts of cinnamon bark, 6 parts of astragalus root, 4 parts of liquorice and 12 parts of poria cocos.

3. A rice porridge comprising the medicinal and edible composition of lotus leaf and cassia seed according to claim 1 or 2, characterized in that: The composition comprises the following raw materials in parts by weight: 20-40 parts of polished rice, 20-40 parts of oats, 10-30 parts of soybeans, 5-15 parts of whey protein powder, 5-10 parts of freeze-dried powder of lotus leaf and cassia seed medicinal and edible composition, and 2-8 parts of medium-chain fatty acids.

4. The rice porridge according to claim 3, wherein The preparation comprises the following raw materials in parts by weight: 31 parts of polished round-grained rice, 31 parts of oats, 15 parts of soybeans, 10 parts of whey protein powder, 8 parts of freeze-dried powder of lotus leaf and cassia seed medicinal and edible composition, and 5 parts of medium-chain fatty acids.

5. The method for preparing the lotus leaf and cassia seed medicinal and edible composition according to claim 1 or 2, characterized in that: The following steps are involved: (1) Crush lotus leaves, cassia seeds, cinnamon bark, astragalus root, licorice root, and poria cocos and soak them; (2) First, boil the liquid with "high heat", then simmer with "low heat", and filter to obtain the liquid; (3) The liquid is subjected to rotary evaporation, concentration, and freeze-drying to obtain freeze-dried powder of the lotus leaf and cassia seed medicinal and edible composition.

6. The preparation method according to claim 5, characterized in that In step (1), the crushing method is: after crushing, the mixture is passed through a 60-mesh sieve; and the soaking time is 30 minutes.

7. The preparation method according to claim 5, characterized in that In step (2), the simmering time is 30-60 minutes; and the filtering method is: filtering through 200-mesh gauze.

8. The method for preparing rice porridge as claimed in claim 3 or 4, wherein The following steps are involved: Polished rice, oats and soybeans are crushed and then soaked, cooked for gelatinization, pulped, cooked and crushed; and then mixed with freeze-dried powder of a medicinal and edible composition of lotus leaf and cassia seed, whey protein powder and medium-chain fatty acids to obtain the medicinal and edible composition of lotus leaf and cassia seed.

9. The preparation method according to claim 8, characterized in that The pulverizing method is as follows: after pulverizing, the granules are sieved through a 200-mesh sieve.

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