Application of fenoxazole glycyrrhiza as active ingredient of wheat herbicide and weeding composition

Abstract

The invention discloses an application of fenoxazole liquiritiamine as an active ingredient of a wheat herbicide and a weeding composition, and mainly relates to the technical field of pesticides. The weeding composition is applied to post-emergence weeding of wheat, weeds removed by the weeding composition are gramineous resistant weeds including beckmannia syzigachne, alopecurus ramosutus, alopecurus aequalis, alopecurus japonicus, lolium multiflorum and bromegrass, the weeding composition is compounded with an active component B for use during specific application, and the active component B is selected from one or a combination of more of an ALS inhibitor, an HPPD inhibitor, substituted urea and an ACCase inhibitor. The weeding composition has the beneficial effects that the weeding composition is used before wheat jointing and a four-leaf stage of weeds, has a synergistic effect, and can solve the problem of resistant gramineous weeds in wheat fields.

Description

Technical Field

[0001] The present invention relates to the technical field of pesticides, in particular to the application of fenoxaprop-glycyrrhizin as an active ingredient of a wheat herbicide and a herbicidal composition. Background Art

[0002] Wheat has long been the world's largest grain crop, topping all cereal crops in both acreage and yield. my country's wheat planting area consistently stands at approximately 350 million mu (approximately 1.5 million hectares). Wheat fields are plagued by numerous weed species, causing significant damage and significant yield losses. Surveys show that weed-infested wheat fields account for over 30% of the cultivated area, with 8% experiencing severe damage. Annual wheat production losses due to weed damage total 15%, or approximately 1.5 million tons.

[0003] While chemical control can address weed problems, the widespread use of single pesticides has led to the emergence of weed resistance. Resistance is particularly prevalent among grass weeds in wheat fields, with resistant ryegrass in Henan, resistant bromegrass in Hebei, and resistant alopecuroides in Jiangsu being the most severe. Summary of the Invention

[0004] The object of the present invention is to provide the use of fenoxaprop-glycyrrhizin as an active ingredient of a wheat herbicide and a herbicidal composition. The herbicidal composition has a synergistic effect when used before wheat jointing and before the weeds reach the 4-leaf stage, and can solve the problem of resistant grass weeds in wheat fields.

[0005] To achieve the above-mentioned purpose, the present invention is implemented through the following technical solutions:

[0006] A wheat field weed control composition comprises fenoxaprop-glycyrrhizin and an active ingredient B, wherein the active ingredient B is selected from one or a combination of ALS inhibitors, HPPD inhibitors, substituted ureas and ACCase inhibitors.

[0007] Preferably, the ALS inhibitor includes one or a combination of mesosulfuron, thiamethoxam, pyrasulfuron, and fluazifop-methyl;

[0008] and / or

[0009] The HPPD inhibitor includes one or a combination of cypermethrin;

[0010] and / or

[0011] The substituted urea is isoproturon;

[0012] and / or

[0013] The ACCase inhibitor includes one or a combination of trimethylol, pinoxaden, clodinafop-butyl, and fenoxaprop-butyl.

[0014] Preferably, the active ingredient B includes one or a combination of mesosulfuron, formosulam, fluazifop-butyl, isoproturon, trimethylol, pinoxaden, and clodinafop-butyl.

[0015] Preferably, the weight ratio of the oxadiazol glycyrrhizin to the active ingredient B is 1:28 to 20:1.

[0016] Preferably, the content of the oxadiazol glycyrrhizin and active ingredient B in the herbicidal composition is 20%-80% by mass, and the composition also includes adjuvants and / or solvents and / or carriers allowed in pesticide formulations to prepare a dosage form allowed by the pesticide, and the dosage form includes oil suspension, suspension concentrate, aqueous emulsion, microemulsion, water dispersible granules, and wettable powder.

[0017] Preferably, the auxiliary agent is one or more of an emulsifier, a synergist, a stabilizer, a dispersant, a wetting agent, a penetrant, an antifreeze agent and a spreader;

[0018] The solvent is one or more of dimethyl sulfoxide, acetone, butanone, cyclohexanone, pyrrolidone, isopropyl alcohol, butanol, ethylene glycol, ethyl acetate, butyl acetate, acetonitrile, tetrahydrofuran, engine oil, vegetable oil and methyl oleate;

[0019] The carrier is one or more of bentonite, diatomaceous earth, kaolin, talc, clay, mica, zeolite, pyrophyllite, white carbon black, light calcium carbonate and ammonium sulfate.

[0020] Preferably, the emulsifier is a monomer or compound preparation of a nonionic surfactant, a cationic surfactant or an anionic surfactant;

[0021] The synergist is methylated and / or ethylated vegetable oil, and / or menthol;

[0022] The penetrant is one or more of sulfated castor oil, sodium alkyl sulfonate, sodium alkylbenzene sulfonate, azone, thiazone and organosilicon.

[0023] Preferably, the nonionic surfactant is one or more of alkylphenol polyoxyethylene ether, alkylphenol polyoxypropylene ether, benzylphenol polyoxyethylene ether, phenethyl polyoxyethylene polyoxypropylene ether, fatty acid ethylene oxide ester and sorbitan fatty acid ester;

[0024] The cationic surfactant is one or more of fatty amine salts, fatty primary amine salts and fatty secondary amine salts;

[0025] The anionic surfactant is one or more of alkylbenzene sulfonate calcium, alkyl calcium sulfonate, alkyl sodium sulfate, fatty alcohol polyoxyethylene ether calcium sulfate, phenethylphenol polyoxyethylene ether sulfate and alkyl polyoxyethylene ether phosphate.

[0026] Preferably, the invention is used for weeding after wheat seedlings, and the weeds removed are resistant grass weeds, including foxtail millet, foxtail alopecuroides, foxtail alopecuroides, Japanese foxtail alopecuroides, multiflora ryegrass, and brome.

[0027] The application of fenoxaprop glycyrrhizin as an active ingredient of a wheat herbicide is applied to post-emergence weeding of wheat. The weeds to be removed are resistant grass weeds, including gramineous weed, giant alopecuroid, alopecuroides, Japanese alopecuroides, multiflora ryegrass, and brome. In specific applications, the active ingredient B is used in combination with an active ingredient B, and the active ingredient B is selected from one or a combination of ALS inhibitors, HPPD inhibitors, substituted ureas, and ACCase inhibitors.

[0028] Compared with the prior art, the beneficial effects of the present invention are:

[0029] The active ingredient, fenoxazol glycyrrhizin, is chemically known as (R)-(2-(4-(6-chlorobenzoxazole-2-oxy)phenoxy)propionyl)glycine ethyl ester. Its synergistic combination with active ingredient B is an effective measure to expand the weed control spectrum, improve control efficacy, and reduce weed resistance. It is highly effective against difficult-to-control weeds in wheat fields, including multiflora ryegrass, bromegrass, and alopecuroides. It is also safe for wheat and can effectively control difficult-to-control grass weeds in wheat fields. It has the advantages of expanding the weed control spectrum, reducing application rates, producing synergistic effects, and addressing resistant weeds. Its advantages include:

[0030] 1. High herbicidal activity: The mixed herbicidal composition of the present invention can kill weeds through two different mechanisms of action, reduce the development of weed resistance, and greatly improve the herbicidal activity of the herbicide.

[0031] 2. Control resistant weeds and delay weed resistance. The mixed herbicidal composition of the present invention improves the control effect on resistant weeds and reduces weed resistance to the agent, thereby extending the service life of the agent by compounding high-efficiency ingredients with different action mechanisms.

[0032] 3. Complete weed control without rebound. The active ingredient, oxazolidinone, in this invention has not been used in wheat fields. Through extensive experimental research, the inventors found that oxazolidinone has high activity against grass weeds in wheat fields and has a synergistic effect when used in combination with active ingredient B, achieving the effect of completely killing weeds without rebound.

[0033] 4. Highly safe for wheat: The herbicidal composition of the present invention is highly safe for wheat when sprayed on the stems and leaves from the 3-leaf 1-heart stage to the greening and jointing stage. DETAILED DESCRIPTION

[0034] Below in conjunction with specific embodiment, further set forth the present invention.Should be understood that these embodiments are only used to illustrate the present invention and are not used in limiting the scope of the present invention.In addition, should be understood that after reading the content taught by the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalent forms fall within the scope limited by the application equally.

[0035] Unless otherwise specified, the instruments, reagents, and materials used in the following examples are all conventional instruments, reagents, and materials available in the prior art and can be obtained through regular commercial channels. The experimental methods and detection methods used in the following examples are all conventional experimental methods and detection methods available in the prior art, unless otherwise specified.

[0036] Example 1:

[0037] The composition of this example includes 20% of fenoxaprop-glycyrrhizin, 5% of fluazifop-methyl, 8% of adjuvant, and 67% of carrier.

[0038] Among them, the additives are 2.5% dispersant 2700 and 5.5% wetting agent T-1004;

[0039] The carrier is 15% ammonium sulfate and 52% kaolin.

[0040] The above composition ratios are all percentages by weight.

[0041] Based on the above components and proportions, all raw materials are fully mixed, air flow crushed, mixed, granulated, dried and sieved to obtain a granular agent with a moisture content of 25%.

[0042] Example 2:

[0043] The composition of this example includes 12% of fenoxaprop-glycyrrhizin, 13% of mesosulfuron-methyl, 18% of an adjuvant, 40.5% of a solvent and 16.5% of a carrier.

[0044] Among them, the adjuvants are 7% dispersant T-80, 3% Nongru 601# and 11% Nongru 500#;

[0045] The solvent was methyl oleate;

[0046] The carrier is 7.5% organic bentonite and 9% white carbon black.

[0047] The above composition ratios are all percentages by weight.

[0048] Based on the above components and proportions, all raw materials are fully mixed and then sand-milled to obtain a 25% oil suspension.

[0049] Example 3:

[0050] The composition of this example includes 5% of fenoxaprop-glycyrrhizin, 70% of isoproturon, 5% of an adjuvant and 20% of a carrier.

[0051] Among them, 2% wetting agent K-12 and 3% dispersant MF-5;

[0052] The carrier is 13% white carbon black and 7% kaolin.

[0053] The above composition ratios are all percentages by weight.

[0054] Based on the above components and proportions, all raw materials are fully mixed and then subjected to air flow grinding to obtain 75% wettable powder.

[0055] Example 4:

[0056] The composition of this example includes 16% of fenoxaprop-glycyrrhizin, 2% of formosansulfuron, 21% of adjuvant, 44.5% of solvent and 16.5% of carrier.

[0057] Among them, the adjuvants are 7% dispersant T-80, 3% Nongru 601# and 11% Nongru 500#;

[0058] The solvent was methyl oleate;

[0059] The carrier is 6.5% organic bentonite and 9% white carbon black.

[0060] The above composition ratios are all percentages by weight.

[0061] Based on the above components and proportions, all raw materials were fully mixed and then sand-milled to obtain an 18% oil suspension.

[0062] Example 5:

[0063] The composition of this example includes 6% of fenoxaprop-glycyrrhizin, 36% of mesotrione, 17% of adjuvant, 24.5% of solvent and 16.5% of carrier.

[0064] Among them, the adjuvants are 7% dispersant T-80, 3% Nongru 601# and 7% Nongru 500#;

[0065] The solvent is water;

[0066] The carrier is 7.5% organic bentonite and 9% white carbon black.

[0067] The above composition ratios are all percentages by weight.

[0068] Based on the above components and proportions, all raw materials were fully mixed and then sand-milled to obtain a 42% suspension concentrate.

[0069] Example 6:

[0070] The composition of this example includes 16% of pinoxazoline, 10% of pinoxazoline-butyl, 21% of adjuvant, 36.5% of solvent and 16.5% of carrier.

[0071] Among them, the adjuvants are 7% dispersant T-80, 3% Nongru 601# and 11% Nongru 500#;

[0072] The solvent was methyl oleate;

[0073] The carrier is 6.5% organic bentonite and 9% white carbon black.

[0074] The above composition ratios are all percentages by weight.

[0075] Based on the above components and proportions, all raw materials were fully mixed and then sand-milled to obtain a 26% oil suspension.

[0076] Example 7:

[0077] The composition of this example includes 16% of fenoxaprop-propargyl, 15% of clodinafop-propargyl, 18% of adjuvant, 32.5% of solvent and 18.5% of carrier.

[0078] Among them, the adjuvants are 7% dispersant T-80, 4% Nongru 601# and 7% Nongru 500#;

[0079] The solvent is water;

[0080] The carrier is 8.5% organic bentonite and 10% white carbon black.

[0081] The above composition ratios are all percentages by weight.

[0082] Based on the above components and proportions, all raw materials were fully mixed and then sand-milled to obtain a 31% suspension concentrate.

[0083] Example 8:

[0084] The herbicide compositions prepared in Examples 1-8 were used to conduct indoor herbicidal activity and wheat safety tests.

[0085] Test method: Indoor potting method, a certain amount of resistant alopecuroides, resistant multiflora ryegrass, and resistant brome were sown in 9 cm diameter seedling pots, with about 20 weed seeds sown in each pot. They were cultured in a plant culture room. When the resistant alopecuroides, resistant multiflora ryegrass, and resistant brome were in the 3-leaf stage, they were sprayed on a 3WP-2000 walking spray tower, with 3 pots of seeds per treatment. The materials were placed in the plant culture room for cultivation, and the effects of each treatment on weed control were observed regularly. After 15 days, the aboveground part Fresh weight, fresh weight inhibition rate (%) was used to evaluate the toxicity of the pesticide to the target weeds.

[0086] Calculation method:

[0087]

[0088] Test results:

[0089] Table 1 Results of indoor toxicity test of the herbicidal composition of the present invention on wheat field weeds

[0090]

[0091] The results of the indoor weed toxicity test show that the composition of the present invention has excellent control effects on the difficult-to-control weeds in wheat fields, such as Alopecurus alopecurus, Lolium multiflorum, and Bromus spp., and the combination of the active ingredient oxazolidinone and the active ingredient B has a significant synergistic effect.

[0092] Safety investigations were conducted on wheat under each treatment, and visual inspections showed that all treatments were safe for wheat, with no obvious symptoms of phytotoxicity.

[0093] Example 9

[0094] Field efficacy and safety test of the composition of the present invention on wheat

[0095] A total of 6 test sites were selected in Yangzhou, Jiangsu, Zhumadian, Henan, and Handan, Hebei for field efficacy tests.

[0096] Test agent:

[0097] The seven binary compound herbicides in Examples 1 to 7.

[0098] Control agents: 36% clomazone SC + 50% isoproturon WP, 6% pinoxafil-butyl EC, 70% fluazifop-methyl WG + 4% pinoxafil OD.

[0099] Test crop: wheat

[0100] Treatment method: Spray treatment on stems and leaves during the three-leaf stage of wheat seedlings

[0101] Targets:

[0102] Jiangsu region: Mainly Alopecurus mume, with a small amount of sedge, hard grass, and multi-flowered ryegrass in Henan region, a small amount of brome, mainly brome in Hebei region, and a small amount of large-eared Alopecurus mume.

[0103] Test method:

[0104] Accurately weigh each pesticide according to the size of the test plot, dilute with water, and evenly spray using a backpack sprayer. Use a fan-shaped nozzle designed for herbicides. Ensure the pesticide solution is evenly applied to the test plot, avoiding any missed or oversprayed areas.

[0105] In the wheat field test, the weed mortality was investigated 15 days after the application of the medicine, and the herbicidal activity of various pesticides was compared. In addition, the growth of wheat was observed within 1 to 25 days after the application of the medicine (the dosage was the dosage of the active ingredient per mu of land) to examine whether the pesticide had any phytotoxicity to the crops.

[0106] Digital survey method:

[0107]

[0108] Results of pesticide efficacy 15 days after spraying on wheat stems and leaves (Yangzhou, Jiangsu)

[0109]

[0110]

[0111] Results of pesticide efficacy 15 days after spraying on wheat stems and leaves (Zhumadian, Henan)

[0112]

[0113] Results of pesticide efficacy 15 days after spraying on wheat stems and leaves (Handan, Hebei)

[0114]

[0115] After the application of the medicine, the safety of wheat in each test plot was continuously observed and recorded. There was no obvious phytotoxicity symptom in the growth of wheat in each treatment compared with the blank control, and the wheat in each treatment was safe.

[0116] The present invention has been verified through a large number of experiments and field trials in typical resistant weed areas. The active ingredient oxazolidinone and active ingredient B can be used in combination to achieve excellent control effects on difficult-to-control resistant weeds in wheat fields, which is significantly higher than the control effects of local conventional pesticides. At the same time, the active ingredient oxazolidinone has not been used in wheat fields. The combination of different ingredients can reduce the development of weed resistance, and each treatment is safe for wheat.

Claims

1. A wheat field herbicidal composition, characterized in that: The components include fenoxapro glycyrrhizin and active ingredient B, wherein the active ingredient B is selected from one or a combination of ALS inhibitors, HPPD inhibitors, substituted ureas and ACCase inhibitors.

2. A wheat field herbicidal composition according to claim 1, characterized in that, The ALS inhibitor includes one or a combination of mesosulfuron, thiamethoxam, pyrasulfuron, and fluazifop-methyl; and / or The HPPD inhibitor includes one or a combination of cypermethrin; and / or The substituted urea is isoproturon; and / or The ACCase inhibitor includes one or a combination of trimethylol, pinoxaden, clodinafop-butyl, and fenoxaprop-butyl.

3. A wheat field herbicidal composition according to claim 2, characterized in that, The active ingredient B includes one or a combination of several of mesosulfuron, pyrasulfuron, fluazifop-butyl, isoproturon, trimethylol, pinoxaden, and clodinafop-butyl.

4. A wheat field herbicidal composition according to claim 1, characterized in that: The weight ratio of the oxadiazol glycyrrhizin to the active ingredient B is 1:28 to 20:

1.

5. A wheat field herbicidal composition according to claim 1, characterized in that, The content of the oxazolidinone glycyrrhizin and active ingredient B in the herbicidal composition is 20%-80% by mass, and the composition also includes adjuvants and / or solvents and / or carriers allowed in pesticide formulations to be formulated into a dosage form allowed for pesticides, and the dosage form includes oil suspensions, suspension concentrates, aqueous emulsions, microemulsions, water dispersible granules, and wettable powders.

6. A wheat field herbicidal composition according to claim 1, characterized in that: The auxiliary agent is one or more of an emulsifier, a synergist, a stabilizer, a dispersant, a wetting agent, a penetrant, an antifreeze agent and a spreader; The solvent is one or more of dimethyl sulfoxide, acetone, butanone, cyclohexanone, pyrrolidone, isopropyl alcohol, butanol, ethylene glycol, ethyl acetate, butyl acetate, acetonitrile, tetrahydrofuran, engine oil, vegetable oil and methyl oleate; The carrier is one or more of bentonite, diatomaceous earth, kaolin, talc, clay, mica, zeolite, pyrophyllite, white carbon black, light calcium carbonate and ammonium sulfate.

7. A wheat field herbicidal composition according to claim 6, characterized in that: The emulsifier is a monomer or compound preparation of a nonionic surfactant, a cationic surfactant or an anionic surfactant; The synergist is methylated and / or ethylated vegetable oil, and / or menthol; The penetrant is one or more of sulfated castor oil, sodium alkyl sulfonate, sodium alkylbenzene sulfonate, azone, thiazone and organosilicon.

8. A wheat field herbicidal composition according to claim 1, characterized in that: The nonionic surfactant is one or more of alkylphenol polyoxyethylene ether, alkylphenol polyoxypropylene ether, benzylphenol polyoxyethylene ether, phenylethyl polyoxyethylene polyoxypropylene ether, fatty acid ethylene oxide ester and sorbitan fatty acid ester; The cationic surfactant is one or more of fatty amine salts, fatty primary amine salts and fatty secondary amine salts; The anionic surfactant is one or more of alkylbenzene sulfonate calcium, alkyl calcium sulfonate, alkyl sodium sulfate, fatty alcohol polyoxyethylene ether calcium sulfate, phenethylphenol polyoxyethylene ether sulfate and alkyl polyoxyethylene ether phosphate.

9. A wheat field herbicidal composition according to claim 1, characterized in that: In specific application, it is used for post-emergence weeding of wheat, and the weeds removed are resistant weeds of the Poaceae family, including foxtail millet, giant foxtail, foxtail, Japanese foxtail, multiflora ryegrass, and brome.

10. Use of fenoxapro glycyrrhizin as an active ingredient in a wheat herbicide, characterized in that: The invention is used for post-emergence weeding of wheat. The weeds removed are resistant grass weeds, including gramineous weed, giant alopecuroides, alopecuroides, Japanese alopecuroides, multiflora ryegrass, and brome. When used, the invention is compounded with active ingredient B, which is selected from one or a combination of ALS inhibitors, HPPD inhibitors, substituted ureas, and ACCase inhibitors.

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