Ovarian tissue sampling device

Abstract

The invention provides an ovarian tissue sampling device which comprises a connecting sleeve with an opening in one end, an outer sleeve needle tube communicated with the connecting sleeve is outwards arranged on the connecting sleeve, the position, close to the connecting sleeve, of the outer sleeve needle tube is outwards communicated with a connecting sleeve, the connecting sleeve is in sliding connection with a driving needle cylinder, and one end of the driving needle cylinder is communicated with an inner sleeve needle tube extending into the outer sleeve needle tube; a plurality of supporting sliding strips making contact with the inner wall of the outer sleeve needle tube are arranged on the outer wall of the inner sleeve needle tube, a suction cup capable of retracting into the outer sleeve needle tube is arranged at the free end of the inner sleeve needle tube, and a plurality of negative pressure holes communicated with the interior of the outer sleeve needle tube are formed in the suction cup in a penetrating mode. The driving needle cylinder is connected with a sampling needle which extends into the inner sleeve needle tube and can penetrate out of the suction cup, a sampling hook groove is formed in the side, away from one end of the pressed piston, of the sampling needle, the driving needle cylinder is connected with a piston rod used for driving the sampling needle to stretch out and draw back, and a push piece is arranged at the free end of the piston rod. When ovary puncture sampling is carried out, an ovary can be fixed, and the accuracy of puncture sampling is effectively improved.

Description

Technical Field

[0001] The invention belongs to the technical field of medical devices and relates to an ovarian tissue sampling device. Background Art

[0002] Accurately obtaining ovarian tissue samples for pathological examination is crucial for the diagnosis and treatment of gynecological diseases, especially for the early detection and confirmation of ovarian cancer. As a highly malignant tumor of the female reproductive system, ovarian cancer often presents with subtle early symptoms, often leading to late-stage diagnosis, which increases the difficulty and complexity of treatment. Therefore, effective ovarian sampling and pathological examination are crucial steps in the early detection and diagnosis of ovarian cancer.

[0003] Traditional methods for diagnosing ovarian cancer mainly include imaging examinations (such as ultrasound, CT or MRI) and blood tumor marker tests (such as CA-125). However, these methods can only provide indirect evidence and cannot directly determine the nature of the lesion. In order to make a clear diagnosis, it is usually necessary to obtain ovarian tissue samples for pathological analysis. Existing methods for ovarian tissue sampling mainly include surgical resection and fine needle aspiration (FNA), among which fine needle aspiration is widely used due to its minimally invasive nature.

[0004] However, in actual operation, especially when using fine needle aspiration for ovarian tissue sampling, the ovary is located in the pelvic cavity and is surrounded by abundant ligament structures (such as the suspensory ligament and the proper ligament of the ovary), which allows it to move to a certain extent. This sliding phenomenon may bring certain difficulties to the sampling process, which may not only affect the accuracy of sampling, but also lead to sampling failure or require multiple attempts to successfully obtain sufficient tissue samples. Summary of the Invention

[0005] The object of the present invention is to provide an ovarian tissue sampling device, which can fix the ovary during ovarian puncture sampling and effectively improve the accuracy of puncture sampling.

[0006] In order to solve the above technical problems, the present invention provides an ovarian tissue sampling device, comprising a connecting sleeve with an opening at one end, the connecting sleeve being connected to an outer sleeve needle tube in a direction away from the opening, the outer sleeve needle tube being connected to a connecting sleeve outwardly near the connecting sleeve, the connecting sleeve being slidably connected to a driving syringe, one end of the driving syringe being connected to an inner sleeve needle tube extending into the outer sleeve needle tube, the outer diameter of the inner sleeve needle tube being smaller than the inner diameter of the outer sleeve needle tube, the outer wall of the inner sleeve needle tube being provided with a plurality of supporting slide bars arranged along the length direction thereof and in contact with the inner wall of the outer sleeve needle tube, the end of the inner sleeve needle tube away from the driving syringe being provided with a suction cup capable of being retracted into the outer sleeve needle tube, the suction cup being provided with a plurality of negative pressure holes communicating with the inner sleeve needle tube;

[0007] The driving syringe is provided with an extrusion chamber and a piston chamber that are interconnected. The inner diameter of the extrusion chamber is larger than the inner diameter of the piston chamber. A telescopic sliding hole that is connected to the inner trocar tube is provided at the bottom of the extrusion chamber. A pressure piston is slidably connected to the extrusion chamber. The pressure piston is connected to a sampling needle that passes through the telescopic sliding hole, extends into the inner trocar tube and can pass through the suction cup. A sampling hook groove is provided on one side of the free end of the sampling needle. A driving piston is slidably connected to the piston chamber. Hydraulic oil is provided between the driving piston and the pressure piston. The driving piston is connected to a piston rod outwardly. A push piece is provided at the free end of the piston rod.

[0008] By adopting the above technical solution, when sampling ovarian tissue, first use the puncture needle to puncture, and after the puncture is completed, use the cannula needle to widen it. After removing the puncture needle, use the device to insert the outer needle tube into the cannula needle. After entering, push the driving syringe into the connecting sleeve to extend the inner needle tube, push the suction cup to extend from the outer needle tube and expand, and after connecting the connecting sleeve to the negative pressure device, the outer needle tube is generated by the negative pressure device. Then, negative pressure is generated at the suction cup along the negative pressure hole, and the ovary is aimed at, and the suction cup can be used to suck the ovary;

[0009] After positioning is completed, the push piece is pressed, and the driving piston is pushed by the piston rod to push the hydraulic oil from the piston chamber into the extrusion chamber. During the process, since the inner diameter of the extrusion chamber is larger than the inner diameter of the piston chamber, the displacement path of the driving piston is larger than the displacement path of the pressure piston. A longer displacement path can make the sampling needle move shorter, which is convenient for fine control of puncture and allows the sampling needle to penetrate into the ovary. Then, the push piece is pushed in the opposite direction to transfer the hydraulic oil from the extrusion chamber to the piston chamber. The sampling needle is pulled back into the inner needle tube through the pressure piston, and the sampling is completed through the sampling hook groove.

[0010] Turn the inner airway tube to connect the airway hole with the ventilation tube, so that the suction cup loses negative pressure and releases the ovary, and then the driving syringe can be pulled out from the connecting sleeve, so that the inner needle tube drives the suction cup back into the outer needle tube, and finally the outer needle tube is pulled out, and the push piece is pushed to extend the sampling needle out of the sampling hook groove, and the sample tissue is removed from the sampling hook groove to complete a biopsy sampling.

[0011] The present invention is further configured such that each supporting slide does not extend to the connecting sleeve, the connecting sleeve is externally connected to a negative pressure connecting pipe and a ventilation pipe, an inner air guide pipe is rotatably connected inside the connecting sleeve, the outer diameter of the inner air guide pipe is equal to the inner diameter of the connecting sleeve, an air guide hole that cooperates with the negative pressure connecting pipe and the ventilation pipe is opened on the side wall of the inner air guide pipe, a knob is provided at one end of the inner air guide pipe extending out of the connecting sleeve, and an arrow pointing to the air guide hole is provided on the outside of the knob.

[0012] The present invention is further configured such that the inner wall of the connecting sleeve is symmetrically provided with two limit slots arranged along its length direction between the negative pressure connecting pipe and the ventilation pipe, and the outer wall of the inner air guide pipe is provided with a limit strip that cooperates with the limit slots. When the limit strip is respectively engaged with the two limit slots, the air guide hole is respectively connected with the negative pressure connecting pipe or the ventilation pipe.

[0013] The present invention is further configured such that the inner wall of the connecting sleeve is provided with an internal thread, and the outer wall of the driving syringe is provided with an internal thread threadedly connected to the inner wall of the connecting sleeve.

[0014] The present invention is further configured such that the suction cup is made of silicone material.

[0015] The present invention is further configured such that the piston rod outer sleeve is provided with a return spring located between the push piece and the drive syringe.

[0016] The present invention is further configured such that a limiting sliding hole is provided at the top of the piston cavity, and the free end of the piston rod passes through the limiting sliding hole.

[0017] The present invention is further configured such that a plurality of through holes are provided at the bottom of the driving syringe, a plurality of air inlet and outlet holes are provided at the bottom of the connecting sleeve, and an inner diameter of the limiting sliding hole is larger than an outer diameter of the piston rod.

[0018] The present invention is further configured such that ears are provided on two opposite sides of the driving syringe away from one end of the inner sleeve needle tube.

[0019] The present invention is further configured such that the hydraulic oil is silicone oil.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] First, when performing ovarian puncture sampling, the present invention uses a suction cup that can be extended to generate negative pressure to suck the ovary and locate the ovary. After the sampling needle is extended from the middle of the suction cup, the ovary is punctured and sampled. This can effectively prevent the ovary from sliding and displacement, reduce the difficulty of puncture, and facilitate complete sampling in one go.

[0022] Secondly, the present invention drives the design of the extrusion chamber and the piston chamber in the syringe. Since the inner diameter of the extrusion chamber is larger than that of the piston chamber, the displacement path of the driving piston is larger than that of the pressure piston. A longer displacement path can make the sampling needle move shorter, which is convenient for fine control of puncture. At the same time, it meets the usage habits of the syringe and can achieve puncture with a shorter path by pushing deeply enough, which is more convenient to use.

[0023] Third, by connecting the inner airway tube and the connecting sleeve, the negative pressure and non-negative pressure states of the suction cup can be easily adjusted, which is convenient for rapid adjustment according to needs, and the position of the ovary adsorption can be quickly adjusted. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0025] Figure 2 Used to demonstrate the connection between the connecting sleeve and the inner airway tube;

[0026] Figure 3 Used to show the air inlet and outlet holes at the bottom of the connecting sleeve;

[0027] Figure 4 Used to demonstrate the connection between the drive syringe, inner needle tube and suction cup;

[0028] Figure 5 It is a partial cross-sectional view used to show the pressurized piston and the driving piston in the driving syringe;

[0029] Figure 6 It is a partial cross-sectional view used to show the internal structure of the driving syringe;

[0030] Figure 7 It is a schematic diagram of the overall structure of the sampling needle.

[0031] Among them, 1. connecting sleeve; 2. outer needle tube; 3. driving syringe; 4. inner needle tube; 5. supporting slide; 6. suction cup; 7. negative pressure hole; 8. connecting sleeve; 9. negative pressure connecting tube; 10. ventilation tube; 11. inner air guide tube; 12. air guide hole; 13. knob; 14. limiting card slot; 15. limiting card strip; 16. extrusion chamber; 17. piston chamber; 18. through hole; 19. air inlet and outlet holes; 20. telescopic slide hole; 21. pressure piston; 22. sampling needle; 23. sampling hook groove; 24. perforation; 25. limiting slide hole; 26. driving piston; 27. piston rod; 28. push piece; 29. reset spring; 30. ear. DETAILED DESCRIPTION

[0032] The following is a detailed description of an ovarian tissue sampling device according to the present invention, with reference to the accompanying drawings and specific embodiments. The advantages and features of the present invention will become more apparent from the following description. It should be noted that the drawings are highly simplified and not to exact scale, and are intended solely to facilitate and clearly illustrate the embodiments of the present invention. Identical or similar reference numerals in the drawings represent identical or similar components.

[0033] Example, see Figure 1-7An ovarian tissue sampling device includes a connecting sleeve 1 with an opening at one end. The connecting sleeve 1 is provided with an outer sleeve needle tube 2 connected to it in the direction away from its opening. The connecting sleeve 1 is slidably connected to a driving syringe 3. The inner wall of the connecting sleeve 1 is provided with an internal thread, and the outer wall of the driving syringe 3 is provided with an internal thread connected to the inner wall of the connecting sleeve 1, so as to facilitate the adjustment of the depth of the driving syringe 3 inserted into the connecting sleeve 1. One end of the driving syringe 3 is connected to an inner sleeve needle tube 4 that extends into the outer sleeve needle tube 2 and is slidably connected thereto. The outer diameter of the inner sleeve needle tube 4 is smaller than the inner diameter of the outer sleeve needle tube 2. The outer wall of the inner sleeve needle tube 4 is provided with a plurality of support slides 5 arranged along its length direction and in contact with the inner wall of the outer sleeve needle tube 2. A ventilation channel is formed between every two support slides 5. The end of the inner sleeve needle tube 4 away from the driving syringe 3 is provided with a suction cup 6 that can be retracted into the outer sleeve needle tube 2. The suction cup 6 is made of silicone material. A plurality of negative pressure holes 7 that are connected to the inner sleeve needle tube 2 are opened through the suction cup 6. The negative pressure holes 7 are connected to the ventilation channel, so that the suction cup 6 can generate negative pressure.

[0034] The outer sleeve needle tube 2 is connected to a connecting sleeve 8 outward near the connecting sleeve 1. Each support slide 5 does not extend to the connecting sleeve 8. The connecting sleeve 8 is connected to a negative pressure connecting pipe 9 and a ventilation pipe 10 outward. An inner air guide tube 11 is rotatably connected to the connecting sleeve 8. The outer diameter of the inner air guide tube 11 is equal to the inner diameter of the connecting sleeve 8. The side wall of the inner air guide tube 11 is provided with an air guide hole 12 that cooperates with the negative pressure connecting pipe 9 and the ventilation pipe 10. A knob 13 is provided at one end of the inner air guide tube 11 extending from the connecting sleeve 8. The connecting sleeve 8 The inner wall of the inner air guide tube 11 is symmetrically provided with two limit slots 14 arranged along its length direction between the negative pressure connecting tube 9 and the ventilation tube 10, and the outer wall of the inner air guide tube 11 is provided with a limit card strip 15 that cooperates with the limit card slot 14. When the limit card strip 15 is respectively engaged with the two limit card slots 14, the air guide hole 12 is respectively connected with the negative pressure connecting tube 9 or the ventilation tube 10, which is convenient for adjusting the negative pressure and non-negative pressure states, and an arrow pointing to the air guide hole 12 is provided on the outside of the knob 13, which is convenient for judging whether the air guide hole 12 is connected with the negative pressure connecting tube 9 or the ventilation tube 10.

[0035] The driving syringe 3 is provided with an extrusion chamber 16 and a piston chamber 17 which are interconnected. The inner diameter of the extrusion chamber 16 is larger than the inner diameter of the piston chamber 17. The bottom of the driving syringe 3 is provided with a plurality of through holes 18, and the bottom of the connecting sleeve 1 is provided with a plurality of air inlet and outlet holes 19, so that air can be discharged or inhaled from the extrusion chamber 16. The bottom of the extrusion chamber 16 is provided with a telescopic sliding hole 20 which is connected to the inner trocar tube 4. A pressure-bearing piston 21 is slidably connected to the extrusion chamber 16. The pressure-bearing piston 21 is connected to a sampling needle 22 which passes through the telescopic sliding hole 20 and extends into the inner trocar tube 4 and can pass through the suction cup 6. The free end of the sampling needle 22 is pointed. A sampling hook groove 23 is provided on the side of the sampling needle 22 away from the end of the pressure piston 21. A through hole 24 for the sampling needle 22 to extend is provided in the middle of the suction cup 6. A limiting sliding hole 25 is provided on the top of the piston chamber 17. 7 is slidably connected to a driving piston 26, and hydraulic oil is provided between the driving piston 26 and the pressure piston 21. The hydraulic oil is silicone oil. The driving piston 26 is connected outwardly to a piston rod 27 extending out of the limiting sliding hole 25. The inner diameter of the limiting sliding hole 25 is larger than the outer diameter of the piston rod 27, so that the piston cavity 17 can discharge or inhale air. The free end of the piston rod 27 is provided with a push piece 28, and the piston rod 27 is covered with a return spring 29 located between the push piece 28 and the driving syringe 3. The driving syringe 3 is provided with ears 30 on both sides opposite to the end away from the inner sleeve needle tube 4.

[0036] Working principle: When sampling ovarian tissue, first use the puncture needle to puncture. After the puncture is completed, use the cannula needle to widen it. After removing the puncture needle, use this device to insert the outer sleeve needle tube 2 into the cannula needle. After entering, rotate the driving syringe 3 to extend the inner sleeve needle tube 4, push the suction cup 6 to extend from the outer sleeve needle tube 2 and expand. After connecting the negative pressure connecting tube 9 to the negative pressure device, rotate the inner air guide tube 11 to connect the air guide hole 12 with the negative pressure connecting tube 9. The negative pressure device generates negative pressure on the outer sleeve needle tube 2, and then generates negative pressure on the suction cup 6 along the negative pressure hole 7. Aim at the ovary, and then use the suction cup 6 to suck the ovary;

[0037] After positioning is completed, the push piece 28 is pressed, and the driving piston 26 is pushed by the piston rod 27 to push the hydraulic oil from the piston chamber 17 into the extrusion chamber 16. During the process, since the inner diameter of the extrusion chamber 16 is larger than the inner diameter of the piston chamber 17, the displacement path of the driving piston 26 is larger than the displacement path of the pressure piston 21. A longer displacement path can make the sampling needle 22 move shorter, which is convenient for fine control of puncture, so that the sampling needle 22 is inserted into the ovary. After releasing the push piece 28, the piston rod 27 is pushed back to its original position under the action of the reset spring 29, so that the hydraulic oil is transferred from the extrusion chamber 16 to the piston chamber 17, and the sampling needle 22 is pulled back into the inner cannula tube 4 through the pressure piston 21, and the sampling is completed through the sampling hook groove 23;

[0038] The inner airway tube 11 is rotated to connect the airway hole 12 with the ventilation tube 10, so that the suction cup 6 loses the negative pressure and releases the ovary. The drive syringe 3 can then be rotated in the reverse direction, so that the inner needle tube 4 drives the suction cup 6 back into the outer needle tube 2. Finally, the outer needle tube 2 is pulled out, and the push piece 28 is pushed to extend the sampling needle 22 out of the sampling hook groove 23. The sample tissue is removed from the sampling hook groove 23 to complete a biopsy.

[0039] It should also be noted that all “disposed” and similar descriptive words in this application (especially in the specification) express that there is or exists a connection relationship between two structures, but the specific means by which the two are connected are not too limited, and are generally conventional connection means, that is, it should be understood that the means are prior art and do not need to be elaborated on. For example, “n is disposed on m” simply expresses that structure n is present on structure m, and the two are specifically connected by welding, riveting, adhesive bonding or integral molding, which are all within the scope of protection of this application; for another example, “y is rotatably disposed on x” simply expresses that y and x can rotate relative to each other, and whether the two are connected by bearings, or y directly passes through x and is connected to x by rotation, or other feasible methods, are all within the scope of protection of this application.

[0040] The above description is only a description of the preferred embodiments of the present invention and does not limit the scope of the present invention. Any changes and modifications made by ordinary technicians in the field of the present invention based on the above disclosure shall fall within the scope of protection of the claims.

Claims

1. An ovarian tissue sampling device, comprising a connecting sleeve (1) with an open end, characterized in that: The connecting sleeve (1) is connected to an outer sleeve needle tube (2) in a direction away from its opening, and the outer sleeve needle tube (2) is connected to a connecting sleeve (8) outward near the connecting sleeve (1). The connecting sleeve (1) is slidably connected to a driving syringe (3), and one end of the driving syringe (3) is connected to an inner sleeve needle tube (4) extending into the outer sleeve needle tube (2). The outer diameter of the inner sleeve needle tube (4) is smaller than the inner diameter of the outer sleeve needle tube (2). The outer wall of the inner sleeve needle tube (4) is provided with a plurality of supporting slides (5) arranged along its length direction and in contact with the inner wall of the outer sleeve needle tube (2). The end of the inner sleeve needle tube (4) away from the driving syringe (3) is provided with a suction cup (6) that can be retracted into the outer sleeve needle tube (2), and a plurality of negative pressure holes (7) communicating with the inner sleeve needle tube (2) are opened through the suction cup (6); The driving syringe (3) is provided with an extrusion chamber (16) and a piston chamber (17) which are communicated with each other. The inner diameter of the extrusion chamber (16) is larger than the inner diameter of the piston chamber (17). A telescopic sliding hole (20) which is communicated with the inner trocar tube (4) is provided at the bottom of the extrusion chamber (16). A pressure piston (21) is slidably connected in the extrusion chamber (16). The pressure piston (21) is connected with a sampling needle (22) which passes through the telescopic sliding hole (20) and extends into the inner trocar tube (4) and can pass through the suction cup (6). A sampling hook groove (23) is provided on one side of the free end of the sampling needle (22). A driving piston (26) is slidably connected in the piston chamber (17). Hydraulic oil is provided between the driving piston (26) and the pressure piston (21). The driving piston (26) is externally connected to a piston rod (27). A push piece (28) is provided at the free end of the piston rod (27).

2. The ovarian tissue sampling device according to claim 1, characterized in that: Each supporting slide bar (5) does not extend to the connecting sleeve (8), the connecting sleeve (8) is connected to the negative pressure connecting pipe (9) and the ventilation pipe (10) outwardly, the connecting sleeve (8) is rotatably connected to the inner air guide pipe (11), the outer diameter of the inner air guide pipe (11) is equal to the inner diameter of the connecting sleeve (8), the side wall of the inner air guide pipe (11) is provided with an air guide hole (12) that matches the negative pressure connecting pipe (9) and the ventilation pipe (10), and a knob (13) is provided at one end of the inner air guide pipe (11) extending out of the connecting sleeve (8), and an arrow pointing to the air guide hole (12) is provided on the outer side of the knob (13).

3. The ovarian tissue sampling device according to claim 2, characterized in that: The inner wall of the connecting sleeve (8) is symmetrically provided with two limit slots (14) arranged along its length direction between the negative pressure connecting pipe (9) and the ventilation pipe (10); the outer wall of the inner air guide pipe (11) is provided with a limit clip (15) matched with the limit slots (14); when the limit clip (15) is respectively engaged with the two limit slots (14), the air guide hole (12) is respectively communicated with the negative pressure connecting pipe (9) or the ventilation pipe (10).

4. The ovarian tissue sampling device according to claim 1, characterized in that: The inner wall of the connecting sleeve (1) is provided with an internal thread, and the outer wall of the driving syringe (3) is provided with an internal thread that is threadedly connected to the inner wall of the connecting sleeve (1).

5. The ovarian tissue sampling device according to claim 1, characterized in that: The suction cup (6) is made of silica gel.

6. The ovarian tissue sampling device according to claim 1, characterized in that: The piston rod (27) is covered with a return spring (29) located between the push piece (28) and the driving syringe (3).

7. The ovarian tissue sampling device according to claim 1, characterized in that: A limiting sliding hole (25) is provided at the top of the piston cavity (17), and the free end of the piston rod (27) passes through the limiting sliding hole (25).

8. The ovarian tissue sampling device according to claim 7, characterized in that: The bottom of the driving syringe (3) is provided with a plurality of through holes (18), the bottom of the connecting sleeve (1) is provided with a plurality of air inlet and outlet holes (19), and the inner diameter of the limiting sliding hole (25) is larger than the outer diameter of the piston rod (27).

9. The ovarian tissue sampling device according to claim 1, characterized in that: Ears (30) are provided on both sides of the driving syringe (3) that are opposite to one end away from the inner sleeve needle tube (4).

10. The ovarian tissue sampling device according to claim 1, characterized in that: The hydraulic oil is silicone oil.

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