Hydrophobic physical sun-screening agent composition and preparation method and application thereof

Abstract

The invention provides a composition of a hydrophobic physical sun-screening agent as well as a preparation method and application of the composition, and belongs to the field of cosmetics. The composition comprises a hydrophobic physical sun-screening agent, nonionic polyglycerol fatty acid ester, an alkyl glycoside emulsifier, polysaccharide, an amino acid emulsifier, polyol and a solvent, the solvent is water. The composition is prepared by adopting the composition formula provided by the invention, the hydrophobic physical sun-screening agent is high in dispersion speed and dispersion uniformity, does not need to be wetted by grease, can disperse the high-content hydrophobic physical sun-screening agent, has excellent high-temperature stability and mechanical stability, and has unexpected excellent technical effects.

Description

Technical Field

[0001] The present invention relates to the field of cosmetics, and in particular to a hydrophobic physical sunscreen composition, a preparation method and an application thereof. Background Art

[0002] my country's Cosmetics Safety Technical Specifications stipulate that physical sunscreens include titanium dioxide and zinc oxide. To reduce the photochemical activity of physical sunscreens, prevent aggregation, and optimize skin feel, they are typically treated with hydrophobic surface treatments, typically with stearic acid, triethoxycaprylylsilane, or hydrogenated polydimethylsiloxane.

[0003] Typically, physical sunscreens with hydrophobic surface treatments require about 0.8-1.5 times the amount of oil to wet and disperse them. This means that when the amount of physical sunscreen added is high, the amount of oil used is also relatively high. High oil content in products has the following four disadvantages:

[0004] (1) The skin feels greasy and the consumer experience is poor;

[0005] (2) Oil and fat account for a large proportion of the cost, and the total cost of the product is high;

[0006] (3) The total amount of oil phase is large, and the flexibility of formula preparation is low;

[0007] (4) High amounts of oil added may lead to the risk of osmotic irritation.

[0008] Therefore, there is still an urgent need for a composition of a physical suntanning agent with a hydrophobic surface treatment that has good skin feel, low oil phase content or even no oil phase required, low irritation, good dispersibility, and fast dispersion speed, and a preparation method thereof. Summary of the Invention

[0009] In order to solve the above technical problems, the present invention provides the following technical solutions.

[0010] In a first aspect, the present invention provides a composition of a hydrophobic physical sunscreen agent.

[0011] A hydrophobic physical sunscreen composition comprises: a hydrophobic physical sunscreen, a nonionic polyglycerol fatty acid ester, an alkyl glycoside emulsifier, a polysaccharide, an amino acid emulsifier, a polyol and a solvent; the solvent is water.

[0012] In some embodiments, the hydrophobic physical sunscreen comprises at least one of titanium dioxide with a hydrophobic surface treatment or zinc oxide with a hydrophobic surface treatment.

[0013] In some embodiments, the surface hydrophobic treatment includes treatment with a hydrophobic surface treatment agent; the hydrophobic surface treatment agent includes one or more of stearic acid, isostearic acid, aluminum hydroxide, hydrated silica, triethoxycaprylylsilane, hydrogenated polydimethylsiloxane, etc.

[0014] In some embodiments, the hydrophobic physical sunscreen includes at least one of titanium dioxide hydrophobized with aluminum hydroxide and stearic acid, titanium dioxide hydrophobized with aluminum hydroxide and isostearic acid, titanium dioxide hydrophobized with aluminum hydroxide, hydrated silica and hydrogenated polydimethylsiloxane, titanium dioxide hydrophobized with aluminum hydroxide and hydrogenated polydimethylsiloxane, titanium dioxide hydrophobized with triethoxycaprylylsilane, zinc oxide hydrophobized with triethoxycaprylylsilane, zinc oxide hydrophobized with hydrated silica and hydrogenated polydimethylsiloxane, and zinc oxide hydrophobized with polyhydroxystearic acid.

[0015] In some embodiments, the nonionic polyglyceryl fatty acid ester is polyglyceryl-10 diisostearate.

[0016] In some embodiments, the alkyl glycoside emulsifier is an aqueous solution of octyl / decyl glucoside or octyl / decyl glucoside.

[0017] In some embodiments, the polysaccharide is inulin.

[0018] In some embodiments, the amino acid emulsifier is an aqueous solution of sodium di(laurylamideglutamine)lysine or sodium di(laurylamideglutamine)lysine.

[0019] In some embodiments, the polyols are glycerol and butylene glycol.

[0020] In some embodiments, the octyl / decyl glucoside aqueous solution is composed of 50 wt% to 70 wt% octyl / decyl glucoside, with the balance being water. In some embodiments, the octyl / decyl glucoside aqueous solution is composed of 50 wt%, 55 wt%, 60 wt%, 65 wt% or 70 wt% octyl / decyl glucoside, with the balance being water. In some embodiments, the octyl / decyl glucoside aqueous solution is composed of 55 wt% to 65 wt% octyl / decyl glucoside, with the balance being water. In some embodiments, the octyl / decyl glucoside aqueous solution is composed of 60 wt% octyl / decyl glucoside, with the balance being water.

[0021] In some embodiments, the di(laurylamide glutamine) sodium lysine aqueous solution is composed of 20wt%-40wt% of di(laurylamide glutamine) sodium lysine, and the balance is water. In some embodiments, the di(laurylamide glutamine) sodium lysine aqueous solution is composed of 20wt%, 25wt%, 26wt%, 27wt%, 28wt%, 29wt%, 30wt%, 31wt%, 32wt%, 33wt%, 34wt%, 35wt% or 40wt% of di(laurylamide glutamine) sodium lysine, and the balance is water. In some embodiments, the di(laurylamide glutamine) sodium lysine aqueous solution is composed of 25wt%-35wt% or 40wt% of di(laurylamide glutamine) sodium lysine, and the balance is water. In some embodiments, the di(laurylamide glutamine) sodium lysine aqueous solution is composed of 29wt% of di(laurylamide glutamine) sodium lysine, and the balance is water.

[0022] In some embodiments, the content of the hydrophobic physical sunscreen is ≤70.000 wt % based on the total mass of the composition. In some embodiments, the content of the hydrophobic physical sunscreen is 30.000 wt %-70.000 wt % based on the total mass of the composition. In some embodiments, the content of the hydrophobic physical sunscreen is 30.000 wt %, 35.000 wt %, 40.000 wt %, 45.000 wt %, 50.000 wt %, 55.000 wt %, 60.000 wt %, 65.000 wt % or 70.000 wt % based on the total mass of the composition.

[0023] In some embodiments, the content of the nonionic polyglycerol fatty acid ester is 1.000wt%-6.000wt% based on the gross mass of the composition. In some embodiments, the content of the nonionic polyglycerol fatty acid ester is 1.000wt%, 2.000wt%, 3.000wt%, 4.000wt%, 5.000wt% or 6.000wt% based on the gross mass of the composition.

[0024] In some embodiments, the content of octyl / decyl glucoside or octyl / decyl glucoside in the aqueous solution of octyl / decyl glucoside in the composition is 0.060 wt%-3.600 wt% based on the total mass of the composition. In some embodiments, the content of octyl / decyl glucoside or octyl / decyl glucoside in the aqueous solution of octyl / decyl glucoside in the composition is 0.060 wt%, 0.100 wt%, 0.150 wt%, 0.180 wt%, 0.200 wt%, 0.250 wt%, 0.300 wt%, 0.400 wt%, 0.500 wt%, 0.600 wt%, 0.700 wt%, 0.800 wt%, 0.900 wt%, 1.000 wt%, 1.10 0wt%, 1.200wt%, 1.300wt%, 1.400wt%, 1.500wt%, 2.000wt%, 2.100wt%, 2.200wt%, 2.300wt%, 2.400wt%, 2.500wt%, 2.600wt%, 2.700wt%, 2.800wt%, 2.900wt%, 3.000wt%, 3.100wt%, 3.200wt%, 3.300wt%, 3.400wt%, 3.500wt% or 3.600wt%.

[0025] In some embodiments, the content of the octyl / decyl glucoside aqueous solution in the composition is 0.100 wt%-6.000 wt%, calculated based on the total mass of the composition. In some embodiments, the content of the octyl / decyl glucoside aqueous solution in the composition is 0.100 wt%, 0.200 wt%, 0.300 wt%, 0.400 wt%, 0.500 wt%, 1.000 wt%, 1.500 wt%, 2.000 wt%, 2.500 wt%, 3.000 wt%, 3.500 wt%, 4.000 wt%, 4.500 wt%, 5.000 wt%, 5.500 wt% or 6.000 wt%, calculated based on the total mass of the composition.

[0026] In some embodiments, the polysaccharide content is 0.500 wt%-12.000 wt% based on the total weight of the composition. In some embodiments, the polysaccharide content is 0.500 wt%, 1.000 wt%, 2.000 wt%, 3.000 wt%, 4.000 wt%, 5.000 wt%, 6.000 wt%, 7.000 wt%, 8.000 wt%, 9.000 wt%, 10.000 wt%, 11.000 wt% or 12.000 wt% based on the total weight of the composition.

[0027] In some embodiments, the content of sodium di(laurylamide glutamine) lysine or sodium di(laurylamide glutamine) lysine in the aqueous solution of sodium di(laurylamide glutamine) lysine in the composition is 0.020 wt % to 1.800 wt % based on the total mass of the composition. In some embodiments, the content of sodium di(laurylamide glutamine) lysine or sodium di(laurylamide glutamine) lysine in the aqueous solution of sodium di(laurylamide glutamine) lysine in the composition is 0.029 wt % to 1.740 wt % based on the total mass of the composition. In some embodiments, based on the total mass of the composition, the content of sodium di(laurylamide glutamine) lysine or sodium di(laurylamide glutamine) lysine in the aqueous solution of sodium di(laurylamide glutamine) lysine in the composition is 0.020 wt%, 0.029 wt%, 0.050 wt%, 0.100 wt%, 0.200 wt%, 0.250 wt%, 0.290 wt%, 0.300 wt%, 0.350 wt%, 0.400 wt%, 0.450 wt%, 0.500 wt%, 0.580 wt%. %, 0.600wt%, 0.650wt%, 0.700wt%, 0.750wt%, 0.800wt%, 0.850wt%, 0.870wt%, 0.900wt%, 0.950wt%, 1.000wt%, 1.100wt%, 1.150wt%, 1.160wt%, 1.200wt%, 1.300wt%, 1.400wt%, 1.450wt%, 1.500wt%, 1.600wt%, 1.700wt%, 1.740wt% or 1.800wt%.

[0028] In some embodiments, the content of the sodium di(laurylamide glutamine) lysine aqueous solution in the composition is 0.100wt%-6.000wt% based on the total mass of the composition. In some embodiments, the content of the sodium di(laurylamide glutamine) lysine aqueous solution in the composition is 0.100wt%, 0.200wt%, 0.500wt%, 1.000wt%, 2.000wt%, 3.000wt%, 4.000wt%, 5.000wt% or 6.000wt% based on the total mass of the composition.

[0029] In some embodiments, the content of the polyol is 10.000 wt% to 20.000 wt% based on the total mass of the composition. In some embodiments, the content of the polyol is 10.000 wt%, 12.000 wt%, 15.000 wt% or 20.000 wt% based on the total mass of the composition.

[0030] In some embodiments, the sum of the content of octyl / decyl glucoside or octyl / decyl glucoside in the aqueous solution of octyl / decyl glucoside plus the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in the composition is 1.400 wt % to 3.700 wt %, calculated based on the total mass of the composition. In some embodiments, based on the total mass of the composition, the sum of the content of octyl / decyl glucoside in the composition or the octyl / decyl glucoside aqueous solution plus the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine is 1.400 wt%, 1.450 wt%, 1.460 wt%, 1.470 wt%, 1.480 wt%, 1.490 wt%, 1.500 wt%, 1.600 wt%, 1.630 wt%, 1.700 wt%, 1.710 wt%, 1.720 wt%, 1.730 wt%, 1.740 wt%, 1.750 wt%, 1.760 wt%, 1.770 wt%, 1.780 wt%, 1.790 wt%, 1.800 wt%, 1.810 wt%, 1.820 wt%, 1.830 wt%, 1.840 wt%, 1.850 wt%, 1.860 wt%, 1.870 wt%, 1.880 wt%, 1.890 wt%, 1.900 wt%, 1.910 wt%, 1.920 wt%, 1.930 wt%, 1.940 wt%, 1.950 wt%, 1.960 wt%, 1.970 wt%, 1.980 wt%, 1 .650wt%, 1.700wt%, 1.750wt%, 1.760wt%, 1.770wt%, 1.780wt%, 1.790wt%, 1.800wt%, 1.810wt%, 1.820wt%, 1.850wt%, 1.900wt%, 1.950wt%, 2.000wt%, 2.500wt%, 2.600wt%, 2.650wt%, 2.690wt%, 2.700wt%, 3.000wt%, 3.500wt% or 3.700wt%.

[0031] In some embodiments, the sum of the content of the aqueous solution of octyl / decyl glucoside plus the content of the aqueous solution of sodium di(laurylamide glutamine)lysine in the composition is 4.000 wt% to 6.500 wt%, calculated based on the total mass of the composition. In some embodiments, the sum of the content of the aqueous solution of octyl / decyl glucoside plus the content of the aqueous solution of sodium di(laurylamide glutamine)lysine in the composition is 4.000 wt%, 4.500 wt%, 5.000 wt%, 5.100 wt%, 5.200 wt%, 5.300 wt%, 5.400 wt%, 5.500 wt%, 6.000 wt%, 6.100 wt%, 6.200 wt%, 6.300 wt%, 6.400 wt% or 6.500 wt%, calculated based on the total mass of the composition.

[0032] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 30.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 1.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 3.600 wt%; the content of the polysaccharide is 0.500 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 0.029 wt%; the content of the polyol is 20.000 wt%; and the balance is water.

[0033] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 30.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 1.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 3.600 wt%; the content of the polysaccharide is 0.500 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 0.029 wt%; the content of the polyol is 20.000 wt%; the balance is water; the polyol is glycerol and butylene glycol, and the mass ratio of glycerol to butylene glycol is 1:1. In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 40.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 2.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 2.400 wt%; the content of the polysaccharide is 2.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 0.290 wt%; the content of the polyol is 20.000 wt%; and the balance is water.

[0034] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 40.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 2.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 2.400 wt%; the content of the polysaccharide is 2.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 0.290 wt%; the content of the polyol is 20.000 wt%; the balance is water; the polyol is glycerol and butylene glycol, and the mass ratio of glycerol to butylene glycol is 1:1.

[0035] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 2.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 1.200 wt%; the content of the polysaccharide is 4.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 0.580 wt%; the content of the polyol is 20.000 wt%; and the balance is water.

[0036] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 2.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 1.200 wt%; the content of the polysaccharide is 4.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 0.580 wt%; the content of the polyol is 20.000 wt%; the balance is water; the polyol is glycerol and butylene glycol, and the mass ratio of glycerol to butylene glycol is 1:1.

[0037] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 60.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 4.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.600 wt%; the content of the polysaccharide is 6.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 0.870 wt%; the content of the polyol is 20.000 wt%; and the balance is water.

[0038] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 60.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 4.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.600 wt%; the content of the polysaccharide is 6.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 0.870 wt%; the content of the polyol is 20.000 wt%; the balance is water; the polyol is glycerol and butylene glycol, and the mass ratio of glycerol to butylene glycol is 1:1.

[0039] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 70.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 4.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.300 wt%; the content of the polysaccharide is 8.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.160 wt%; the content of the polyol is 10.000 wt%; and the balance is water.

[0040] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 70.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 4.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.300 wt%; the content of the polysaccharide is 8.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.160 wt%; the content of the polyol is 10.000 wt%; the balance is water; the polyol is glycerol and butylene glycol, and the mass ratio of glycerol to butylene glycol is 1:1.

[0041] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 60.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 6.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.180 wt%; the content of the polysaccharide is 10.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.450 wt%; the content of the polyol is 12.000 wt%; and the balance is water.

[0042] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 60.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 6.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.180 wt%; the content of the polysaccharide is 10.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.450 wt%; the content of the polyol is 12.000 wt%; the balance is water; the polyol is glycerol and butylene glycol, and the mass ratio of glycerol to butylene glycol is 1:1.

[0043] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 6.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.060 wt%; the content of the polysaccharide is 12.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.740 wt%; the content of the polyol is 20.000 wt%; and the balance is water.

[0044] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 6.000 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.060 wt%; the content of the polysaccharide is 12.000 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.740 wt%; the content of the polyol is 20.000 wt%; the balance is water; and the polyol is glycerol.

[0045] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50 wt%; the content of the nonionic polyglycerol fatty acid ester is 5.00 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.24 wt%; the content of the polysaccharide is 10.00 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.45 wt%; the content of the polyol is 15.00 wt%; and the balance is water.

[0046] In some embodiments, based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50 wt%; the content of the nonionic polyglycerol fatty acid ester is 5.00 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.24 wt%; the content of the polysaccharide is 10.00 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.45 wt%; the content of the polyol is 15.00 wt%; the balance is water; and the polyol is glycerol.

[0047] In a second aspect, the present invention provides a method for preparing the composition described in the first aspect.

[0048] A method for preparing the composition of the first aspect comprises the following steps:

[0049] After the solvent, nonionic polyglycerol fatty acid ester, alkyl glycoside emulsifier, polysaccharide, amino acid emulsifier and polyol are uniformly dissolved, the hydrophobic physical sunscreen is added under stirring and then uniformly dispersed to obtain the composition.

[0050] In some embodiments, the speed of the homogeneous dispersion is 1000 rpm-10000 rpm. In some embodiments, the speed of the homogeneous dispersion is 1000 rpm, 2000 rpm, 3000 rpm, 4000 rpm, 5000 rpm, 6000 rpm, 7000 rpm, 8000 rpm, 9000 rpm or 10000 rpm.

[0051] In a third aspect, the present invention provides an application of the composition described in the first aspect or the composition prepared by the preparation method described in the second aspect.

[0052] A use of the composition of the first aspect or the composition prepared by the preparation method of the second aspect in preparing a sunscreen product.

[0053] Beneficial effects

[0054] Compared with the prior art, the technical solution provided by the present invention has at least one of the following beneficial technical effects:

[0055] (1) Compared with the composition obtained by lacking some components, the present invention contains non-ionic polyglycerol fatty acid ester, alkyl glycoside emulsifier, polysaccharide and amino acid emulsifier at the same time, which is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent, and has unexpected technical effects.

[0056] (2) Compared with other non-ionic polyglycerol fatty acid esters, the present invention uses polyglycerol-10 diisostearate, which is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent, and has unexpected technical effects.

[0057] (3) Compared with other alkyl glycoside emulsifiers, the present invention uses octyl / decyl glucoside or its solution as the alkyl glycoside emulsifier, which is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent, and has unexpected technical effects.

[0058] (4) Compared with other polysaccharides, the use of inulin in the present invention is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent, and has unexpected technical effects.

[0059] (5) Compared with other amino acid emulsifiers, the present invention uses sodium di(laurylamide glutamine) lysine or its solution as an amino acid emulsifier, which is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent, and has unexpected technical effects.

[0060] (6) The hydrophobic physical sunscreen composition provided by the present invention has excellent high temperature stability and mechanical stability, and has unexpected technical effects.

[0061] (7) The present invention can disperse the hydrophobic physical sunscreen agent without using an oil phase, and can disperse a high content of the hydrophobic physical sunscreen agent. The resulting hydrophobic physical sunscreen agent composition has excellent dispersion speed, dispersion uniformity, high temperature stability and mechanical stability, and has unexpected technical effects.

[0062] (8) The composition of the hydrophobic physical sunscreen provided by the present invention is used to prepare a sunscreen product with good stability, good safety and good mildness.

[0063] Terminology

[0064] In the foregoing text of the present invention, all numerical values disclosed herein are approximate, regardless of whether the word "about" or "approximately" is used. Based on the disclosed numbers, the value of each numerical value may vary by less than ±10% or by a reasonable difference deemed by a person skilled in the art, such as ±1%, ±2%, ±3%, ±4%, or ±5%.

[0065] The terms "optional," "optional," or "optionally" mean that the subsequently described event or circumstance may but need not occur.

[0066] The term "and / or" should be understood to mean any one of the options or a combination of any two or more of the options.

[0067] The term "wt%" means percentage by mass.

[0068] The term "W / W" means mass ratio.

[0069] In the description of this specification, the reference terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" mean that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art can combine and combine different embodiments or examples described in this specification and features of different embodiments or examples without contradiction. DETAILED DESCRIPTION

[0070] In order to enable those skilled in the art to better understand the technical solutions of the present invention, some non-limiting embodiments are further disclosed below to further illustrate the present invention in detail.

[0071] The reagents used in the present invention can be purchased from the market or prepared by the method described in the present invention.

[0072] 1. Sources of some reagents of the present invention:

[0073] Table 1: Sources of some reagents of the present invention

[0074]

[0075]

[0076] Table 2: Sources of the reagents in the following examples and comparative examples of the sunscreen products of the present invention

[0077]

[0078]

[0079] 2. Test methods

[0080] 1. Dispersion consumption time (based on the material weight of 500g):

[0081] After uniformly dissolving all components except the hydrophobic physical sunscreen, the hydrophobic physical sunscreen was added at a stirring speed of 200 rpm. The mixture was then transferred to a homogenizer and dispersed at a homogenization speed of 3000 rpm. The homogenization time required in the homogenizer until the powder was completely wetted (no dry powder was visible to the naked eye) was examined.

[0082] 2. Investigation of dispersion uniformity

[0083] Use a four-sided applicator to apply the dispersed physical sunscreen to a 5-micron film on black artificial leather. Allow the film to sit for 30 minutes. Use a colorimeter to measure the color difference ΔE*ab at 10 different locations. A smaller ΔE*ab value indicates more uniform dispersion.

[0084] Examples 1-8: Compositions of hydrophobic physical sunscreens

[0085] Recipe: See Table 3.

[0086] Table 3: Example 1-Example 8 formulations and their dispersion consumption time and dispersion uniformity

[0087]

[0088]

[0089]

[0090] Preparation method: The preparation was carried out according to the operation described in "1. Dispersion consumption time (based on a material weight of 500 g)" above to obtain compositions of hydrophobic physical sunscreen agents of various formulas.

[0091] Comparative Examples 1-4: Missing Elements Test

[0092] Recipe: The recipe of Example 3 was used for investigation. The specific recipe is shown in Table 4.

[0093] Table 4: Comparative Examples 1-4 formulations and their dispersion time and uniformity

[0094]

[0095]

[0096] Preparation method: Prepare according to the operation described in "1. Dispersion consumption time (based on the material weight of 500g)" above.

[0097] Conclusion: Compared with the composition obtained by lacking some components, the present invention contains non-ionic polyglycerol fatty acid ester, alkyl glycoside emulsifier, polysaccharide and amino acid emulsifier at the same time, which is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent.

[0098] Comparative Examples 5-7: Investigation of Nonionic Polyglycerol Fatty Acid Esters

[0099] Formula: The formula of Example 3 was used for investigation. The specific formula is shown in Table 5.

[0100] Table 5: Comparative Examples 5-7 formulations and their dispersion time and uniformity

[0101]

[0102]

[0103] Preparation method: Prepare according to the operation described in "1. Dispersion consumption time (based on the material weight of 500g)" above.

[0104] Conclusion: Compared with other non-ionic polyglycerol fatty acid esters, the use of polyglycerol-10 diisostearate in the present invention is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent.

[0105] Comparative Example 8-Comparative Example 9: Investigation of Alkyl Glycoside Emulsifiers

[0106] Recipe: The recipe was investigated based on Example 3. The specific recipe is shown in Table 6.

[0107] Table 6: Comparative Examples 8-9 formulations and their dispersion time and uniformity

[0108]

[0109]

[0110] Preparation method: Prepare according to the operation described in "1. Dispersion consumption time (based on the material weight of 500g)" above.

[0111] Conclusion: Compared with other alkyl glycoside emulsifiers, the use of octyl / decyl glucoside or its solution as the alkyl glycoside emulsifier in the present invention is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent.

[0112] Comparative Examples 10-12: Investigation of Polysaccharides

[0113] Recipe: The recipe was investigated based on Example 3. The specific recipe is shown in Table 7.

[0114] Table 7: Comparative Examples 10-12 formulations and their dispersion time and uniformity

[0115]

[0116]

[0117] Preparation method: Prepare according to the operation described in "1. Dispersion consumption time (based on the material weight of 500g)" above.

[0118] Conclusion: Compared with other polysaccharides, the use of inulin in the present invention is more conducive to improving the dispersion speed and uniformity of hydrophobic physical sunscreen agents.

[0119] Recipe: The recipe was investigated based on Example 3. The specific recipe is shown in Table 8.

[0120] Table 8: Comparative Examples 13-15 formulations and their dispersion time and uniformity

[0121]

[0122]

[0123] Preparation method: Prepare according to the operation described in "1. Dispersion consumption time (based on the material weight of 500g)" above.

[0124] Conclusion: Compared with other amino acid emulsifiers, the use of sodium di(laurylamide glutamine) lysine or its solution as an amino acid emulsifier in the present invention is more conducive to improving the dispersion speed and uniformity of the hydrophobic physical sunscreen agent.

[0125] Test Example 1: Stability Investigation

[0126] Day 0 test: The hydrophobic physical sunscreen compositions obtained in the above-mentioned Examples or Comparative Examples that were completely wettable within 12 hours were respectively taken and tested for appearance, dispersion uniformity, and odor. The results are shown in Table 9.

[0127] High-Temperature Stability Test: The hydrophobic physical sunscreen compositions obtained in the Examples or Comparative Examples that were completely wettable within 12 hours were placed in sealed containers and then subjected to high-temperature conditions (50°C ± 2°C) for a 30-day stability test. The hydrophobic physical sunscreen compositions of each Example or Comparative Example were tested for appearance, dispersion uniformity, and odor at 0 days and after 30 days of exposure to high-temperature conditions (50°C ± 2°C). If delamination occurred, the compositions were manually shaken until uniform, and the dispersion uniformity was then measured. The results are shown in Table 10.

[0128] Table 9: 0-day test results

[0129]

[0130]

[0131]

[0132] Table 10: Test results after 30 days at high temperature (50°C ± 2°C)

[0133]

[0134]

[0135] Conclusion: The hydrophobic physical sunscreen composition provided by the present invention has excellent high temperature stability.

[0136] Test Example 2: Mechanical Test

[0137] The hydrophobic physical sunscreen compositions of the above-mentioned Examples or Comparative Examples that were completely wettable within 12 hours were centrifuged at 4000 rpm for 30 minutes, samples obtained after 30 days of exposure to high temperature stability test conditions (50°C ± 2°C), and samples obtained after seven cycles of variable temperature testing (50°C for 24 hours followed by exposure to -5°C for 24 hours, for seven cycles). The stability was then compared with that observed under static conditions. The results are shown in Table 11.

[0138] Table 11: Mechanical test stability results

[0139]

[0140]

[0141]

[0142] Conclusion: The composition of the hydrophobic physical sunscreen provided by the present invention has good mechanical stability.

[0143] Example 9 and Comparative Example 16: Preparation of Sunscreen Products

[0144] 1. Preparation of sunscreen products: The hydrophobic physical sunscreen agent composition obtained in Example 3 was used to prepare sunscreen products according to the formula in Table 12, to obtain the sunscreen products of Example 9 and Comparative Example 16, respectively.

[0145] Preparation process:

[0146] (1) Aqueous phase: Mix phase B at 200 rpm, heat to 90°C, and keep warm for 15 min;

[0147] (2) Oil phase: Heat phase A to 90°C and mix well;

[0148] (3) Emulsification: Add the oil phase to the water phase under stirring at 200 rpm and homogenize at 7000 rpm for 5 min, then stir at 150 rpm to cool down;

[0149] (4) Cool to 35°C, add phase C and phase D (do not add phase D in comparative example 16), and stir at 300 rpm for 5 min.

[0150] 2. Accelerated Stability: The sunscreen products of Example 9 and Comparative Example 16 were placed under accelerated conditions (40°C ± 2°C, 75% ± 5% RH) for 6 months. Stability was tested according to the accelerated test method in T_SHFCA 002-2021 Cosmetic Stability Testing Guidelines (issued by the Jiangsu Health Food and Cosmetics Safety Association). Samples were taken at 0 days, 1 month, 2 months, 3 months, and 6 months to test color, properties, odor, cold resistance, heat resistance, pH value, and centrifugation. The results are shown in Table 12.

[0151] Patch test: The sunscreen products of Example 9 and Comparative Example 16 were respectively taken and 50 people were selected for safety evaluation according to the human skin patch test investigation plan in the "Technical Specification for Safety of Cosmetics" (2015 edition). The results are shown in Table 12.

[0152] Table 12: Preparation formula of sunscreen products

[0153]

[0154]

[0155] Results: The sunscreen product prepared using the composition of the hydrophobic physical sunscreen provided by the present invention has good stability, good safety, and good mildness. The method of the present invention has been described through preferred embodiments. It is obvious that relevant personnel can modify or appropriately change and combine the methods and applications described herein within the content, spirit and scope of the present invention to implement and apply the technology of the present invention. Those skilled in the art can refer to the content of this article and appropriately improve the process parameters to achieve it. It is particularly important to point out that all similar replacements and modifications are obvious to those skilled in the art, and they are all considered to be included in the present invention.

Claims

1. A composition of a hydrophobic physical sunscreen, characterized in that: include: Hydrophobic physical sunscreen, nonionic polyglycerol fatty acid ester, alkyl glycoside emulsifier, polysaccharide, amino acid emulsifier, polyol and solvent; the solvent is water.

2. The composition according to claim 1, wherein the hydrophobic physical sunscreen comprises at least one of titanium dioxide having a surface hydrophobic treatment or zinc oxide having a surface hydrophobic treatment.

3. The composition according to claim 2, wherein the surface hydrophobization treatment comprises treatment with a hydrophobic surface treatment agent; the hydrophobic surface treatment agent comprises one or more of stearic acid, isostearic acid, aluminum hydroxide, hydrated silica, triethoxycaprylylsilane, hydrogenated polydimethylsiloxane, etc.; and / or The hydrophobic physical sunscreen includes at least one of titanium dioxide hydrophobized by aluminum hydroxide and stearic acid, titanium dioxide hydrophobized by aluminum hydroxide and isostearic acid, titanium dioxide hydrophobized by aluminum hydroxide, hydrated silica and hydrogenated polydimethylsiloxane, titanium dioxide hydrophobized by aluminum hydroxide and hydrogenated polydimethylsiloxane, titanium dioxide hydrophobized by triethoxycaprylylsilane, zinc oxide hydrophobized by triethoxycaprylylsilane, zinc oxide hydrophobized by hydrated silica and hydrogenated polydimethylsiloxane, and zinc oxide hydrophobized by polyhydroxystearic acid.

4. The composition according to any one of claims 1 to 3, wherein the nonionic polyglycerol fatty acid ester is polyglycerol-10 diisostearate; and / or The alkyl glycoside emulsifier is an aqueous solution of octyl / decyl glucoside or octyl / decyl glucoside; and / or The polysaccharide is inulin; and / or The amino acid emulsifier is a di(laurylamide glutamine) sodium lysine aqueous solution or a di(laurylamide glutamine) sodium lysine; and / or The polyol is selected from at least one of glycerol and butylene glycol.

5. The composition according to claim 4, wherein the octyl / decyl glucoside aqueous solution is composed of 50 wt% to 70 wt% of octyl / decyl glucoside and the balance is water; The sodium di(laurylamide glutamine) lysine aqueous solution consists of 20wt%-40wt% of sodium di(laurylamide glutamine) lysine and the balance is water.

6. The composition according to any one of claims 4-5, wherein the content of the hydrophobic physical sunscreen agent is ≤70.000 wt% or 30.000 wt%-70.000 wt%, calculated based on the total mass of the composition; and / or Calculated based on the total mass of the composition, the content of the nonionic polyglycerol fatty acid ester is 1.000wt%-6.000wt%; and / or The content of octyl / decyl glucoside or octyl / decyl glucoside in the aqueous solution of octyl / decyl glucoside in the composition is 0.060 wt% to 3.600 wt% based on the total mass of the composition; or the content of the aqueous solution of octyl / decyl glucoside in the composition is 0.100 wt% to 6.000 wt% based on the total mass of the composition; and / or The content of the polysaccharide is 0.500 wt% to 12.000 wt% based on the total mass of the composition; and / or Calculated based on the total mass of the composition, the content of sodium di(laurylamide glutamine) lysine or sodium di(laurylamide glutamine) lysine in the aqueous solution of sodium di(laurylamide glutamine) lysine in the composition is 0.020wt%-1.800wt% or 0.029wt%-1.740wt%; or, calculated based on the total mass of the composition, the content of the aqueous solution of sodium di(laurylamide glutamine) lysine in the composition is 0.100wt%-6.000wt%; and / or Calculated based on the total mass of the composition, the content of the polyol is 10.000wt%-20.000wt%; and / or Calculated based on the total mass of the composition, the sum of the content of octyl / decyl glucoside or the octyl / decyl glucoside in the aqueous solution of octyl / decyl glucoside plus the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine is 1.400 wt% to 3.700 wt%; or, calculated based on the total mass of the composition, the sum of the content of the aqueous solution of octyl / decyl glucoside plus the content of the aqueous solution of sodium di(lauryl glutamine) lysine is 4.000 wt%. wt%-6.500wt%.

7. The composition according to any one of claims 1 to 6, wherein, calculated based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 30.000 wt%; the content of the nonionic polyglycerol fatty acid ester is 1.000 wt%; the content of the octyl / decyl glucoside or the octyl / decyl glucoside aqueous solution in the composition is 3.600 wt%; the content of the polysaccharide is 0.500 wt%; the content of sodium di(laurylamide glutamine) lysine or the sodium di(laurylamide glutamine) lysine aqueous solution in the composition is 0.029 wt%; the content of the polyol is 20.000 wt%; and the balance is water; or Calculated based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 40.000wt%; the content of the nonionic polyglycerol fatty acid ester is 2.000wt%; the content of the octyl / decyl glucoside or the octyl / decyl glucoside aqueous solution in the composition is 2.400wt%; the content of the polysaccharide is 2.000wt%; the content of sodium di(lauryl glutamine) lysine or the sodium di(lauryl glutamine) lysine aqueous solution in the composition is 0.290wt%; the content of the polyol is 20.000wt%; and the balance is water; or Calculated based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50.000wt%; the content of the nonionic polyglycerol fatty acid ester is 2.000wt%; the content of the octyl / decyl glucoside or the octyl / decyl glucoside aqueous solution in the composition is 1.200wt%; the content of the polysaccharide is 4.000wt%; the content of sodium di(lauryl glutamine) lysine or the sodium di(lauryl glutamine) lysine aqueous solution in the composition is 0.580wt%; the content of the polyol is 20.000wt%; and the balance is water; or Calculated based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 60.000wt%; the content of the nonionic polyglycerol fatty acid ester is 4.000wt%; the content of the octyl / decyl glucoside or the octyl / decyl glucoside aqueous solution in the composition is 0.600wt%; the content of the polysaccharide is 6.000wt%; the content of sodium di(lauryl glutamine) lysine or the sodium di(lauryl glutamine) lysine aqueous solution in the composition is 0.870wt%; the content of the polyol is 20.000wt%; and the balance is water; or Calculated based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 70.000wt%; the content of the nonionic polyglycerol fatty acid ester is 4.000wt%; the content of the octyl / decyl glucoside or the octyl / decyl glucoside aqueous solution in the composition is 0.300wt%; the content of the polysaccharide is 8.000wt%; the content of sodium di(lauryl glutamine) lysine or the sodium di(lauryl glutamine) lysine aqueous solution in the composition is 1.160wt%; the content of the polyol is 10.000wt%; and the balance is water; or Calculated based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 60.000wt%; the content of the nonionic polyglycerol fatty acid ester is 6.000wt%; the content of the octyl / decyl glucoside or the octyl / decyl glucoside aqueous solution in the composition is 0.180wt%; the content of the polysaccharide is 10.000wt%; the content of sodium di(laurylamide glutamine) lysine or the sodium di(laurylamide glutamine) lysine aqueous solution in the composition is 1.450wt%; the content of the polyol is 12.000wt%; and the balance is water; or Calculated based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50.000wt%; the content of the nonionic polyglycerol fatty acid ester is 6.000wt%; the content of the octyl / decyl glucoside or the octyl / decyl glucoside aqueous solution in the composition is 0.060wt%; the content of the polysaccharide is 12.000wt%; the content of sodium di(lauryl glutamine) lysine or the sodium di(lauryl glutamine) lysine aqueous solution in the composition is 1.740wt%; the content of the polyol is 20.000wt%; and the balance is water; or Calculated based on the total mass of the composition, the content of the hydrophobic physical sunscreen is 50 wt%; the content of the nonionic polyglycerol fatty acid ester is 5.00 wt%; the content of octyl / decyl glucoside or octyl / decyl glucoside in an aqueous solution of octyl / decyl glucoside in the composition is 0.24 wt%; the content of the polysaccharide is 10.00 wt%; the content of sodium di(lauryl glutamine) lysine or sodium di(lauryl glutamine) lysine in an aqueous solution of sodium di(lauryl glutamine) lysine in the composition is 1.45 wt%; the content of the polyol is 15.00 wt%; and the balance is water.

8. A method for preparing the composition according to any one of claims 1 to 7, characterized in that: The following steps are involved: After the solvent, nonionic polyglycerol fatty acid ester, alkyl glycoside emulsifier, polysaccharide, amino acid emulsifier and polyol are uniformly dissolved, the hydrophobic physical sunscreen is added under stirring and then uniformly dispersed to obtain the composition. 9 . The preparation method according to claim 8 , wherein the speed of the homogeneous dispersion is 1000 rpm-10000 rpm.

10. Use of the composition according to any one of claims 1 to 7 or the composition prepared by the preparation method according to any one of claims 8 to 9 in preparing a sunscreen product.

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